LOCUS       c00394_gnlPro..         3718 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FHMBPPGG_394.
ACCESSION   c00394_gnlPro..
VERSION     c00394_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:59:13
            Original ID  :: gnl|Prokka|FHMBPPGG_394
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3718
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3718
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:2780]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..2780
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3718
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3718
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..385
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg394_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.4e-33, bitscore:
                     104.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VCFFTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQE
                     LFFHERYSNTIMENPDFVAIAKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVET
                     CGMVYPMVPAGGSVTNMIMGDEK"
     CDS             401..955
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg394_2"
                     /sec_met_domain="ALS_ss_C (E-value: 8.5e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             962..1687
                     /locus_tag="ctg394_3"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             1737..2780
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg394_4"
                     /sec_met_domain="IlvN (E-value: 1.1e-47, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.5e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(2858..3199)
                     /locus_tag="ctg394_5"
                     /transl_table=11
                     /translation="MDGQLSRKKVIGSPIYEESLERIFVEGIERFGIFQARKYLEHILN
                     TVEKLENDYPYYPECRHLATKSRMYRNIILDSHLIIYRITEERIEVLDIAHSASSMRKI
                     KQARNIHIE"
     CDS             complement(3169..3402)
                     /locus_tag="ctg394_6"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTAKTRKAKTEPAKPKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFYPIEEVHQRIRSWMDNYQGKK"
     CDS             complement(3522..3716)
                     /locus_tag="ctg394_7"
                     /transl_table=11
                     /translation="LDQTYPYYPECRHLTTKSRMYRNIILDSHLIIYRITEERIEVLDI
                     VHSASSMRKIKKTRNIHIE"
ORIGIN
        1 ggtctgcttc tttaccggtg atgggggtat gcagatgacg attcaagaat tgggtaccat
       61 catgcaggaa aaactgaacg tgaagattat cattcttaat aataacttct taggtatggt
      121 acgtcagtgg caagaattgt tcttccacga gcgttattca aacaccatca tggagaatcc
      181 ggatttcgtg gcgatcgcta aagcctatgg tatcgccggt cgtgccgttg aaaagcggga
      241 ggaattggac gacgctatcg ctgagatgct aaaccacgac ggcgcttacg tgttggtcgc
      301 taacgtggag acttgcggaa tggtatatcc gatggttcct gccgggggaa gcgtgacaaa
      361 catgattatg ggagacgaga aataaggagg agatgaagct atgacaacaa agaaattata
      421 taccgttatt atcttttcag agaatatcgt aggtcttttg aaccagataa cgattatctt
      481 tacacgccga cagctgaaca tcgagactct gtccgtctct ccgtccgcta tcaagggcat
      541 ccataagttt acgatcacga cattcgccga tgaggatatg atcgataagg tggtgaaaca
      601 gatcgataaa cgtgtggata tcttgaaggc ttattataat acggatgagg atttggttta
      661 tcaagagatc gctctttata agctaagtac cgagcttttc atcaagatgg gaaccgtgga
      721 gggattgatc cgtaaataca acgcccgtat cttggagatg aacgagacct gcgtggtatt
      781 ggagaagagt ggccactatg acgagacaca agccttgttc aatgagttga gcgagacgat
      841 cggtgtcctg caattcatcc gctccggacg tgtggctatc acgaagagca aggtggagcg
      901 cttgagcgat atgttggccg atatggagcg aaagttacat gaaaagcaac aataataaga
      961 tatggagaaa gtaggattat ttcatttcgt ggcggagccg tatttgatgg attttagggg
     1021 acgtgtaacg ctccctatga ttggtaatta tttgattcac gccgcttcca gccatgccgg
     1081 agagcgtggg ttcggtttca atgatatgtc ggagcgtcat acggcttggg tgttgtcccg
     1141 tctggctatc gagatgaagg aatatcctac cgccttcgat aagattaatc tatacacttg
     1201 gatcgatgag gtcggacgcc tcttcaccag ccgttgtttt gagctggcgg atgagaatgg
     1261 gaaaaccttt ggattcgccc gttctatttg ggcggctatc gacgtggaga cccgccgtcc
     1321 taccttattg gatatagagg cattgggcaa atatatcgac gagcgtccgt gcccgatcga
     1381 gaagccgggc aagatcatgc cggcggagaa taaggcggag ggaatcccgt attcgatcaa
     1441 atacagtgac ttggatatca acggtcactt caatagcgtg aagtatatcg agcatctgct
     1501 ggatttgttc gatatcgacc aattcaagac ccgtgagatc ggccgtctgg agatcgccta
     1561 ccaatccgag ggtaaacaag gtatgccgct tacgcttcat aaggcggagt ccgctcccga
     1621 taagcaagac atggctattt gccatgaggg aaaggcgatc tgtcgtgcgg cggttacttg
     1681 gagataataa aagagataca taaataggtt tttaaacatt aatagttaaa aagaaaatgg
     1741 cacaaatgaa ttttggcggt gttgtagaga atgtaatgac ccgcgaggaa tttccgttgg
     1801 aaaaggcaag agagatatta aaagatgaga caatcgctgt tatcggctat ggcgtacagg
     1861 gaccgggaca gtcattgaac cttcgtgaca atggtttcaa cgtaatcgtt ggccagcgcc
     1921 aaggtaagac ttacgataaa gcggttgagg acggatgggt tccgggtgag actctgttcg
     1981 gtatcgagga ggcttgcgac aaggccacga tcatcatgtg cttgttgtcc gacgctgccg
     2041 taatgtctgt atggcctacg atgaagcctt atttgacagc tggcaaggcc ctgtatttct
     2101 ctcatggttt cgcgatcact tggaacgatc gtacgggcgt tgttcctccc gcggatattg
     2161 acgtgatcat ggtcgctccg aaggggtctg gtacgtcttt gcgttccatg ttccttgagg
     2221 gtcgtggctt gaactcttct ttcgctatct atcaagacgc tactggcaag gcgatggatc
     2281 gtacgttggc gttgggtatc ggtatcggtt ccggctactt gttcgagacg actttcatcc
     2341 gtgaggctac ttccgatttg actggtgagc gtggttcttt gatgggcgct atccaaggtt
     2401 tgttgttggc ccagtatgag gtattgcgcg agaatggaca cactccttcc gaggctttca
     2461 acgagacggt cgaggagttg actcaatcct tgatgccttt attcgccaag aatggtatgg
     2521 actggatgta cgcgaactgc tctactaccg cccagcgtgg cgctttggac tggatgggtc
     2581 cgttccacga cgcaatcaag ccggttgtcg agaaattgta cgcaaacgta aaatgcggta
     2641 acgaggctca gatctctatc gactcaaact ctaagccgga ttatcgtgag aaattggagg
     2701 ctgaattgaa ggcattgcgc gagagcgaga tgtggcagac agctgttact gtacgtaagc
     2761 ttcgtccgga gaataactaa tccaatctta atccttatat atcagcaaaa agaggcgggt
     2821 cacttacggg tggctcgcct ttttctgttt ctctgcatca ttcgatgtgg atattcctag
     2881 cctgtttgat ctttcgcatg ctggatgcgg aatgggcgat gtctagcact tcgatacgct
     2941 cctcggtgat gcggtagatg ataaggtgtg aatccaggat gatgttccgg tacatgcggc
     3001 ttttcgtagc taggtgtcgg cattcgggat aataaggata gtcgttttcc agtttctcga
     3061 ctgtattcaa tatgtgctca agatatttcc gggcttggaa tatgccgaat cgttctatac
     3121 cttccacgaa aatcctctca aggctttcct cgtaaatggg agaaccgatt acttttttcc
     3181 ttgatagttg tccatccatg atcttattct ttgatgtact tcttcaatag gatagaacgg
     3241 ccccttctcg atctcatgga tatgttccca gatctcctct tgtgtgaatt gcaccggctt
     3301 ggtgggatcc cacttgggct ttgcgggttc ggtcttggcc ttacgtgtct ttgcggtctt
     3361 ggccgtagtt tccttggcgg ggatgttgct taattttgtc atagtcgtaa tcgttattaa
     3421 ttagtactgt ggcaaatgta tggaataatt tccatgtaat aagatattta atgagtaaaa
     3481 aagaaggcgg gtcacttatg ggtggctcgc ctttcttcgt gttattcgat gtggatattc
     3541 ctagtcttct tgatctttcg catgctggat gctgaatgga cgatgtccag cacctcgatg
     3601 cgttcctcgg tgatgcggta gatgataagg tgtgaatcta ggatgatgtt ccggtacatg
     3661 cggcttttcg tggttaggtg tcggcattcg ggataataag gataggtttg gtctaact
//
