LOCUS       gnlProkkaJJNGJEDH_187   8309 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJNGJEDH_187.
ACCESSION   gnlProkkaJJNGJEDH_187
VERSION     gnlProkkaJJNGJEDH_187
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 17:18:21
            Original ID  :: gnl|Prokka|JJNGJEDH_187
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8309
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8309
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7963:8308]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7964..8308
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..8309
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8309
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             114..1124
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg187_1"
                     /sec_met_domain="PF04055 (E-value: 1.2e-18, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVELQSLTKRLGMPGFAAKQIASWLYEKKVASIDDMTNLSLKH
                     RELLKQNYEVGAEAPVDEMRSVDGTVKYLYKVGENHFVESVYIPDDDRATLCVSSQVGC
                     KMNCKFCMTGKQGYTANLTASQIINQIHSLPERDKLTNVVMMGMGEPLDNLDEVLKALE
                     LLTATYGYAWSPKRITLSTVGLRKGLQRFIEENDCHLAISLHSPLTVQRAELMPAEKAF
                     SITEMVELLKNYDFSKQRRLSFEYIVFKGLNDSQVYAKELLKLLRGLDCRVNLIRFHAI
                     PGVDLEGADMDTMTRFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEKNNES"
     CDS             1143..2183
                     /locus_tag="ctg187_2"
                     /transl_table=11
                     /translation="MKKYSFILCIALVAFVVASCGLKGNHTSSGRAYELLVVVDHGVWD
                     RAAGRALHDALDADMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIIIVDIQDIYTKASF
                     KYAKDVYANPQMILTIQAPNEEEFEKFVEENKKTIVDFFTRAEMNRQITFLEGKHSNFI
                     SQKVDSLFGCDIWVDAELANSKTGDDFFWASTNTGTADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGFKEGVYMSTDSLLTDVRPINVQNSYTMEARGLWRMKGDFMGGPYV
                     SHTRLDEKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPNEVQQKQIPLGEASKE
                     AEQTNK"
     CDS             2188..3282
                     /locus_tag="ctg187_3"
                     /transl_table=11
                     /translation="MEDNKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDIQANFSIVNSATEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGDKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEVIIPAMKEMEEKGILCYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARAN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             3292..4533
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg187_4"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             4520..5047
                     /locus_tag="ctg187_5"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             5053..5826
                     /locus_tag="ctg187_6"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCKKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             5833..6228
                     /locus_tag="ctg187_7"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPATETPAPAAE"
     CDS             6478..7866
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg187_8"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             7964..8308
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg187_9"
                     /sec_met_domain="PqqD_RRE (E-value: 2.1e-11, bitscore:
                     32.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.5e-18, bitscore: 53.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYELRVSAYLSQMQ
                     KDGFIKLVIPV"
ORIGIN
        1 ccttttttgt taacttttac attcctgcta tacggaaatc gactttattt ccttacattt
       61 gcagatataa actatcaaca gaaagaagaa tgtctaaata tcccctttta ggaatgactc
      121 ttgtagagct tcaatcattg acaaaaagac tgggtatgcc cggctttgct gccaagcaga
      181 ttgcatcctg gctttacgaa aagaaggtag cctcgattga tgatatgact aatttgtcat
      241 tgaaacaccg ggagttgctc aagcagaact atgaggtggg agcggaagct ccggtagatg
      301 aaatgcgctc tgtagatggt acggtgaagt atctttataa agtgggtgag aaccattttg
      361 tagagtcggt ttatataccg gatgatgacc gggcaacgtt gtgcgtgtcg tcacaagtgg
      421 gctgcaaaat gaactgtaag ttctgtatga ccggcaaaca ggggtataca gctaacctga
      481 ccgccagcca gatcataaac cagattcatt cgctgccgga acgggacaaa ctgactaatg
      541 tcgtaatgat gggaatgggc gagccgctcg ataacctgga tgaggtattg aaggcattgg
      601 aactactgac cgctacctac ggttacgcat ggagtccgaa gcgtatcacg ctttctactg
      661 tcgggctacg gaaaggattg cagcgtttta tcgaagaaaa tgactgccac cttgccatca
      721 gccttcactc tccgctgacc gttcagcgtg ctgaattaat gccggcggaa aaggcgtttt
      781 caatcaccga aatggtggaa ctgttaaaaa actatgattt tagtaaacaa cgtcgacttt
      841 cgtttgaata tattgttttt aaagggctca atgattcgca ggtctatgcc aaagagttgc
      901 tgaaacttct tcgcgggctg gattgcaggg tgaatctgat tcgttttcat gccataccgg
      961 gggtagacct cgagggagcg gacatggata cgatgacccg ttttcgtgat tatctgacgt
     1021 cacacggact tttcaccact atccgttcat ccaggggcga agatattttt gccgcttgcg
     1081 gtatgctgtc gacagcgaaa caggagaaaa ataatgaaag ttaatatata aaaccgaaca
     1141 tcatgaaaaa gtactctttt attttatgca tcgctttggt agcctttgtc gttgcatctt
     1201 gtggtctgaa aggaaatcac acctctagtg gtcgtgctta cgagcttttg gttgtagtag
     1261 atcacggtgt ttgggatcgt gctgccggaa gggctttaca tgatgcgctc gatgctgata
     1321 tgcccggttt gccgcagtcg gaaccttctt tccggattat gtatacttcg ccgaaagatt
     1381 atgattctac gctgaagttg atacgtaaca ttattattgt agatatacag gatatatata
     1441 cgaaagcctc gttcaaatat gcgaaggacg tgtatgccaa tccgcagatg atattgacta
     1501 tccaggctcc gaacgaagaa gagttcgaga agtttgtgga agagaacaaa aagacgattg
     1561 tcgacttctt tacccgtgcg gagatgaacc gtcagattac gttcctggaa gggaaacaca
     1621 gtaatttcat ttcgcagaaa gtggacagtt tgttcggatg cgacatctgg gtggatgccg
     1681 aactggctaa ttcaaagacc ggggatgatt tcttctgggc ttctaccaac acaggtactg
     1741 ccgaccgtaa ctttgtgatg tactcttatc cgtacactga caaggatacg tttaccaaag
     1801 aatattttgt gcacaaacgt gactccgtga tgaaagccaa tatccccgga ttcaaggaag
     1861 gcgtttatat gtcgaccgat agtttgctga ccgatgtccg tccgatcaat gtacagaaca
     1921 gctacacaat ggaagcacgt ggcttgtggc gtatgaaggg cgactttatg ggtggtccgt
     1981 atgtatctca tactcgtctg gacgagaaaa accaacgaat tattactgca gaaatatttg
     2041 tttattcacc tgataaaatg aaacgcaacc tggtacgcca gatggaagca tctctgtata
     2101 cactgaaact tccgaatgaa gttcagcaga agcagattcc attgggagaa gcatccaagg
     2161 aagcggaaca aactaataaa taaaaacatg gaagataaca agataaggat aggtatcacc
     2221 caaggagata ttaacggggt gggctatgag gtgattctta agacattttc cgaccctacg
     2281 atgttggaac tatgtactcc gatcatttat ggctcaccga aagtagcggc ttatcatcgc
     2341 aaagcgctgg atatacaggc caattttagc attgtcaact ctgctaccga agcggggtac
     2401 aaccgtttga gcgtggtgaa ctgtacggat gatgaggtga aagtggaatt ttccaaaccc
     2461 gaccccgaag ccggtaaagc tgcgctgggg gctttggaac gtgccatcga agaatatcgc
     2521 gaagggttga tagacgttat cgtaacagct ccgatcaaca aacatacgat tcagtcggaa
     2581 gagttctcct tccccggaca tacggaatat atcgaagaac gtctgggcaa tggtgataag
     2641 tcattgatga ttttgatgaa gaatgacttc cgggtggctt tggtgacgac acatatccct
     2701 gtcagagaga tcgcgactac gattaccaaa gaactgattc aggagaaact gatgatattc
     2761 catcgttgtc tgaaacagga tttcggtatc ggtgctccgc gtattgcggt gctctctctc
     2821 aatcctcatg ccggagacgg tggtttgttg ggaatggaag agcaggaagt gattatccct
     2881 gccatgaaag aaatggaaga gaaaggaatc ctttgctacg gtccttatgc ggccgacggc
     2941 tttatgggtt cgggcaatta tactcatttt gatggtatcc tggcgatgta tcacgatcag
     3001 gggctggctc cgttcaaggc cttggctatg gaagacgggg tgaactatac ggcaggactg
     3061 ccggtagtac gtacttctcc ggctcatgga acggcatacg atattgcagg taagggagtg
     3121 gcttgtgaag attctttccg tcaggcaatc tatgttgcca tcgacgtgtt ccgtaatcgt
     3181 cagcgggaaa aagtggctcg tgccaatccg ttgcgtaaac agtattacga gaaacgtgac
     3241 gatagtgata aactgaagct ggatacagta gacgaagatt aaaaacgagt gatgacgaaa
     3301 gcagagatac aacaagtgaa acagcgtttc ggtattattg gaaatactga agcattgtcg
     3361 cgcgccatag atgttgccat tcaggtagct cctaccgatt tgtctgtgct gattaccgga
     3421 gaaagtggag tcggaaaaga aagttttccg cagattattc atcaatatag ccggaggaag
     3481 cacggacagt atattgctgt caactgtggc gctattccgg aaggtacgat tgattccgaa
     3541 ctgttcggac atgagaaagg tgcgtttacc ggtgcgattg gcgaacggaa agggtacttt
     3601 ggcgaagctg acggtggtac tatttttctt gatgaagtag gggagttgcc gatgtctacc
     3661 caggcacgtt tgctccgtgt actggagagt ggcgagttta tgaaagtagg ttcgtccaaa
     3721 gtacaaaaaa cggatgtgcg tgtggtggcg gctaccaatg tcaatctgac acaagcgatt
     3781 gcagaaggac gtttccgtga agatttatat taccggttga atacggtgcc tatccaaata
     3841 ccgcctttgc gtgaacgtgg tgacgatgta cttttgttgt tccgtaagtt ttccgcagac
     3901 tttgcagaga aataccggat gcctgctatt cagttgacgg aggatgcgaa gaaagagttg
     3961 ttggcttacc cgtggcccgg aaacgtgcgc cagttgaaga acatcaccga gcaaatatct
     4021 atcattgaaa ccaacaggga gatctctgct gctatcttgc agaattatct tcctgcacaa
     4081 aatacgcaac gtcttcccgc gttgatggga acgcgtgaga gtaaaggctt tgagagcgaa
     4141 cgggagattc tttattccgt tctgttcgat atgcgccagg aagtggcgga gctgaagaag
     4201 atggtgcaca acctgatggc ggaacgtgcc ggacaggtgg ggcaggtagg acaaatggga
     4261 acggtggtta ctactccggt agtgacggcg catcaacctt cggtacctgc tattattcac
     4321 accatgcagc ctacggtttg caaggatgat gatgacatac aagacacgga agaatatgta
     4381 gaagaatctc ctttgtcact ggatgaagtg gagaaagaaa tgatacgcaa ggcacttgag
     4441 aggcatcatg gaaagcggaa gagtgcggcc aaggacttga atatttccga gcgtacactt
     4501 tatagaaaaa taaaagaata tgaattggat taagaaaata atacgccctt tgttactgtt
     4561 cggcttgccg ttggtagtca ttgcgtgcac tgtttcctat aagtttaacg gatcgtctat
     4621 caattatgat aaggtaaaga ccatttcgat agccgacttc ccgatcaagt cggagtatgt
     4681 atatgctccg ttggcaacca aattcaatga ggacctgaaa gatatcttca tccggcagac
     4741 ccgtctgcaa ctgctcaagc cgaatcagaa tgcggacttg cagattgacg gagaaatcac
     4801 aggatacaat cagtacaacc aggcagtatc tgccgacggt tattcttcgg agacgaagtt
     4861 gactattacc gtcaatgtac gttttgtcaa caacaccaat catgccgaag actttgaaca
     4921 acagttttct gcgttccgta cctacgactc tagccagttg ctgactgccg tacaggacgg
     4981 attgattgct gaaatgtcta aagagatcac cgaccaaatt tttaatgcaa ctgtagcaaa
     5041 ctggtaatat aaatgacttc tgttaacttt caacaatgga ttcagcatcc cgagacgctg
     5101 aatagggata ctttgtacga actgcgcaat cttcttgcga ggtatccgta ttttcagtca
     5161 cttcgtctgc tgtatctgaa gaatctgtat attctccatg atattagttt tggtggagaa
     5221 ctgcggaaag cagttcttta cattgcagac agacggcagt tgttccggtt gattgaaggt
     5281 gaccgctatg atgtgcaagc acggaaaaag ggagtacctc tcacggaggt gctgaaagac
     5341 gaaccgtccg tagaccgcac attagcattg atcgacgctt tcttgtccac agtacccgaa
     5401 gaggtgactg cccgcaccag cttcgactat tcgatggatt acacctctta tcttttggag
     5461 gagactccgg ccacggaaca gccggccgaa gaaacgccca aactcaaagg ctacgaactg
     5521 attgacgact ttatagaaaa gagcgagagc gactctcccc tctgcaagaa acctttaaga
     5581 gaagaaatgc catcttcgcc aacctcttcg gacgaactta ccgaagaaga aacgatgaag
     5641 gaagaagagg aagatgacag ctgttttacg gaaactttgg caaaaatcta tgttaaacag
     5701 caacgatatt caaaagctct tgaaataatt aaaaaattaa gcttgaaata tccaaaaaaa
     5761 aatgcttact ttgcagacca aatcagattt ttggagaaat tgattattaa cgctaattca
     5821 aaataactaa aaatgtactt attattcgtt atcttaatgg ttattgcagc cttgttgatg
     5881 tgtttcatcg tgctgattca gaactcaaaa ggaggcggac ttgcttctgg tttctcttca
     5941 tctaacgcca tcatgggcgt gcgcaagact acagattttc tggaaaaagc aacatggggc
     6001 ttagctatct tcatggtggt aatgagcatt gctactgctt atgtagttcc tcgctctgct
     6061 gttgctaaag acgcagtgtt ggaacaggca cagaaagaac aacagactaa cccgtataac
     6121 ttacccgcag gtacggctgc gccgcaaact gaagctcctg ctaccaatgc acctgctaca
     6181 gaaactccgg caccggctac tgaaactcct gctcctgcag cagagtaatt cactccgttg
     6241 tcaggtaaga ctttggggta aaaccattaa tgggaaggtg cagacggatg ctgcatttct
     6301 ttgatattta agtgcggatt acgcagatta cacggatttt caatcttccg cgtggtcagt
     6361 gtaatccgca cttaactttt tcttgtaaaa acaatctctt tttgatagaa acaaacgaga
     6421 tttaactacc tttgttggtc gtatgaagat tattaactac tatttttaaa tataacaatg
     6481 acagaacatt tgaaacagaa attgaatgac tccgccgtac tccgatggag tgttctagca
     6541 ttagtcgcat ttactatgct atgcggctat ttcctcaccg acgtaatgtc tcctctaaaa
     6601 cccatgcttg agaaagaact actatgggac agtcttgatt atggtttctt cacaagcgct
     6661 tacgggtggt ttaatgtatt cctattgatg ctgattttcg gtggtatcat tttggataag
     6721 atgggagttc gtttcaccgg aatgggagct tgcttattga tggtgtttgg ttgtggattg
     6781 aaatactatg cgatttctac tacttttccg gaaggtgcca tgctcttcgg attcaaaaca
     6841 caggtaaccc tggctgcatt ggggtatgct atcttcggtg taggtgtgga aattgccggt
     6901 atcacagttt ccaaaattat cgtgaaatgg ttcaagggta aggaaatggc attggctatg
     6961 ggacttgaaa tggctacggc acgtatcgga acaactctgg caatggtgct cacggttcct
     7021 ttggccgact ttttcggatc tacggatgag agtggcacat tccataccaa tattcctgct
     7081 ccgattttgt tttgtctgat tatgttgtgc gtgggtacga ttgctttctt cctttatact
     7141 ttctatgata agaagttgga tgcttctttg gatgcagagg gattggaacc ggaagagccg
     7201 ttccgtatga aagatattgt gtatatcatt acgaataagg gattctggtt gattgcatta
     7261 ctatgtgtat tgttctactc ggctgtattc ccctttatca agtatgctgc cgacttgatg
     7321 gtgcagaagt ataatgtaga tccgaagttg gcgggaacga ttcccggatt gttgccgatt
     7381 ggtgcgatta tcctgactcc gttgttcggc tcgctttatg accgtattgg taagggagcc
     7441 acattgatga taatcggatc agtgatgctt atttttgtgc atacgatgtt tgctctgcct
     7501 atactgaata tatggtggtt tgctactatc atcatgatta tattgggatt tgccttctcg
     7561 ttggtgcctt cagctatgtg gccgtctgtt ccgaagatta ttccggaaaa acagttgggt
     7621 accgcatatg cattgatttt ctgggtacag aactggggat tgatgggtgt tcctttgttg
     7681 atcggatggg tgttgaatac ttattgcaaa ggtccggtag tagacggtgc acagacttat
     7741 gattacacgt tgccgatggc tatttttgct ctctttggtg tgcttgctct gattgtggct
     7801 ttgatgttga aggcagagaa caagaagaag ggatacggtt tggaagaggc gaatatccaa
     7861 aagtaactag gaaattcaat acctaaagta acaaaggaat tttgtatcaa ggtgtaaaca
     7921 gaagagtatc agtatgaata ctctgaaata aaaaataaga agtatggctg ccaaagagaa
     7981 aatcaacctg ttagaggtca ttccctgtcg cagtgaacat attacagcag aaagggaagg
     8041 ggagacaatt gtgctctcct ttccccgttt taaatatccg tggatgcaac gcttccttgt
     8101 gccaaaagga atgtcgaaag aacttcatgt gaaattggaa gaacacggta cagctgtatg
     8161 ggaactgata gatggaaaac gcaatgttcg tgagattata gaaaaactcg cagaccactt
     8221 tcaaaatgaa gagggctacg agttgcgtgt atcggcttat ctttctcaaa tgcagaaaga
     8281 tggatttata aaactggtga taccagtcg
//
