LOCUS       c00044_gnlPro..        15687 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IMGDKMAP_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 21:42:21
            Original ID  :: gnl|Prokka|IMGDKMAP_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15687
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..168
                     /locus_tag="ctg44_1"
                     /transl_table=11
                     /translation="VLRIISSFIYLMYARLSVNFCTLIAKTFVFFSHFGRSSKEFVSER
                     RFFVLLKLSD"
     protocluster    1..15687
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4210:5687]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4211..5687
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15687
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15687
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1490..3055)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_2"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.5e-48, bitscore:
                     154.8, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSAMKDQLSGIFSGLVSQYVFDIQVAPDHESRQELIDLLGDVA
                     SCSDHLSCSVADGEGLQFTIVKDGMPTGIRFRAVPNGHEFTSLLLAVLNSDGKGKNIPD
                     ESICARVRALNGPIKLTTYVSLTCTNCPDVVQALNVMATLNSRITHETVDGAINQKEVE
                     AMKVQGVPSVFADGKLINVGRSDLGELLSKLEAQYGINEGGVDNSVEKPVKNYDVLIVG
                     GGPAGAASAIYSARKGLNVAVIAERIGGQVKETVGIENLISVPQTTGKQLANDLLMHIN
                     DYPVDILEHRRVDKVELDGSAKLLTTSTGERFSAPALIVATGASWRKLNVPGEADYIGK
                     GVAFCPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADQVLQEK
                     AKSLPNVEVFLHSQSLEVVGDGDKVTGLRVKDRKTDAERVIDLDGIFVQIGLAANSGVF
                     RDVVETNKPGEIVIDAHCRTNVPGIYAAGDVSTVPYKQIIIAMGEGAKAALSAFEDRMR
                     GPIG"
     CDS             complement(3060..3626)
                     /locus_tag="ctg44_3"
                     /transl_table=11
                     /translation="MEPIINSQVPEFKVQAFQNGSFKTVSSEDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYGKFQEMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKIAEIHDNGIGRNADELLRKVEAAQFVASHP
                     NEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             complement(4211..4942)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73; E-value:
                     9.7e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.3e-35, bitscore:
                     114.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LINMLGRIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWE
                     VKRETPYLLEPEALLAEVLRYKNFIAKGGVTVTGGEPLLQPEFLKEFFRLCRENGIHTA
                     LDTSGYICSGKALEVLEQVDLVLLDIKTIDAGLHPRLTAVKLDNTLRFLDELEKRGIPV
                     WIRHVIVPGLTDDDEALSKLAEYISSYNVVQKAELLPYHTMGAYKYEAQGLDYKLKGVE
                     PLSAERLANAKAIFMKHGITV"
     CDS             complement(4950..5687)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_5"
                     /sec_met_domain="Gly_radical (E-value: 3.7e-46, bitscore:
                     147.4, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6e-39, bitscore:
                     125.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLHDGDVERIRATGIAGLSIVADSLAAIRDTKVKVIRDERGLAV
                     DFEREGEYVPFGNNDDRTDSIAVDITEKFMEYLRQHQTYRKATPTQSILTITSNVVYGK
                     KTGTTPDGRPGGTPFAPGANPMNGRDTKGAVAALASVAKLPFQHAHDGISYTFAVSPAT
                     LGKERDIQINNLVSLLDGYFTPDGGQHLNVNVFDKDLLVDAMEHPEKYPQLTIRVSGYA
                     VNFVKLTREQQLDVISRTINSSL"
     CDS             5715..6755
                     /locus_tag="ctg44_6"
                     /transl_table=11
                     /translation="VHVVNDLQCIDIDFCQPAHHLLVFLHHFVVVQILAGDRFETGSHL
                     HTRFLVTSAIDRIQQALCQVGTSSEILHLLTDLHWRNTAGDTVIVAIVRTHQIVVLVLD
                     GRGIDRYFCAEVFPVIRSIVEPKHRQIGFGCRAEVIQGMQITVRCLCHQRTAVNTLSAQ
                     RFSHPNRVAGEQVVVFRSTQETDNTQFDNKLVDQFLCLFFRQLAFANIFFDIDIEESRS
                     TSERHGCSILILYGCQVSQIQELHGFAGILCRTCHIETITGTHFLKCFQRFDLLRYLLT
                     ALNDFFCQFLYIETFLETFLFFDQDLGSVQRYTTVITDDTSASVSIRQPGNDGGTTCRN
                     HLVCIG"
     CDS             6771..7031
                     /locus_tag="ctg44_7"
                     /transl_table=11
                     /translation="VRLSVFGEDLFCHRVQMITIGFQTVFDHADTAFREDTTFQRGICL
                     QADDYFVFLIDVTGSVCVNPLGKLRFGIIYSFLPFNLKHLG"
     CDS             complement(7618..10722)
                     /locus_tag="ctg44_8"
                     /transl_table=11
                     /translation="MNKKFSTLLTMGLLATSSLCGSAWAQTAPTINGIELEKVAAPANN
                     AAWTGGPYVLVADEDGTLEGSDLLLQAVVSEDGKTVKYYGENLSAFATGAKLKEITWTF
                     TETPVKDVAGVPNGYYYTLTSAASGKPLTVNQSGDLIEKLENCKLDAANHLYTQFSVLS
                     NDFTSRFLQGSGLYPYAGGAGLNPVSLTRAELTSIVGLTGSKLYLYKLKTQELVDQVAV
                     EAMNETMAGEGFNFDFTPKKKLDWANDVLSDVKLKAFYVDNDFDLGNDMKIPAGVYFAT
                     SYPEELVGTDKIADSDLFKQCTFIAIDPTGNYDINATDRDNGLGYELITMQGSEMNFFH
                     GAATSDNFSHAEEVFVGNACFVVEVPNAVTAPETYNIKAKNIHVFVTATDNAAKKHVAK
                     AGLYIGCIADQNKNYMVTTVVTDALAFTTTNTTLLDGDGLVGFLQEEDAPSVYTIQFVS
                     GEKNEGASEYEQYLTVNKPAGFELASTVDFNEADPMYQFVVTGVDKTNKTITLANRQTK
                     VDFTVSLYENEDGVYTVLPATGSKDKVYVEYINGTVGNNSKDEVVTFEAIDLTNMKIVL
                     TPYTVEDKFATFVNRADNMGLVQFELALNSDIAPAFYVGGEKDVDGNLAPNKDILAYAD
                     ADSMVQFELIKSKKPVNVLNNYIYLDGKRIRTSTERDTVAFYTYAVKAFDDANDRYLSN
                     TWELEVATDVSADEFIIKQNLDGSVSLIKAATTTDVNGAFAMVNDLKKDRETAWKDAYN
                     YELEHKIDKGLKTFMVDETPAVSLEAVPQHVSFALTRGGFLTNKDNDAFQSIATEASED
                     LTFWVDTVKSDKNIPTFYISKAGHFLYNAEDSVEYYEARGNYRFNLENQKGEAAKLIFN
                     AGELVSSDTLRTVVDGKSVLVAEKDNAPKKIKGGLDNFQFQIIKAEDGSDEYVIRQGRA
                     NYVQMINSYFYLEANKNTAVRFLIESQSTPTANEGVAVSEVKVLAGEGNVTIAGAAGKK
                     VVISNILGQVVANTVISSDNAVIAAPAGVVVVAVEGEAAVKAIVK"
     CDS             complement(11204..11413)
                     /locus_tag="ctg44_9"
                     /transl_table=11
                     /translation="MKRSLHRHETLVGLFLLVFRADDVPQFHLVADLLFCDPSQASGDF
                     GAVLFHTEQIGGGDVRSIDFYILY"
     CDS             11808..11912
                     /locus_tag="ctg44_10"
                     /transl_table=11
                     /translation="MGNIGTFLPTNCDCTPLTAPLILPKIKKRNEKVN"
     CDS             complement(11929..12192)
                     /locus_tag="ctg44_11"
                     /transl_table=11
                     /translation="LGIEFVIESQDKTGYGDRIAMVFLASVVRTPETVDAVVHKVCEDL
                     PISAEAELVISVGINVCGLFHCGFFCRCFFLFLCKCRYTRGE"
     CDS             complement(12199..12474)
                     /locus_tag="ctg44_12"
                     /transl_table=11
                     /translation="MPGRRKDGRFAFRTRSSEEVDRLMMLVGQTDRDDQMTGTDIEGRM
                     DKTCDVELFQSNFTAFFNFHFVFSVFCVFYLIGTTRTSSLKFYFCS"
     CDS             complement(12661..13059)
                     /locus_tag="ctg44_13"
                     /transl_table=11
                     /translation="VLAFAFLLRVVVFVADERIDDGHVPVVFTNRTQVEPHFATIADRT
                     FGDRGCLCIRRTAALVVVDTAEVVGFAQVAVYHVCACGDIFVFVLQVGRIDAQRYVSIF
                     DVCFRFVGIGSRIVAIVEGTAYFQSRYS"
     CDS             complement(13117..13245)
                     /locus_tag="ctg44_14"
                     /transl_table=11
                     /translation="MLFLFAEEPADVGDGQAEFVFAVIFAASDFACCIVCFHDKIR"
     CDS             13273..14538
                     /locus_tag="ctg44_15"
                     /transl_table=11
                     /translation="MKKKNYFYLAALSLAMTFSMGACSDNNDPNPDGGGKDPVNLDYSS
                     ENASAWGNYMYNVAMLLNDDATTLYNSWVTDYVDEQGSHGPYATIFKDQTAGAYQSPLS
                     CIEEMIESGMWNIANEVGDAKIKDPYTKYTSGDKEGGLYAVESWYSWHSRDDYTNNIFS
                     IRNTYYGRIDDNDVSKVDGNLSAFNSYKDFDDEGDIAEHSLSKLIASTNPDLDEEIKTL
                     IFASAKAIQAIPQPFRNNIDSEESVAAMNTCMELANLLLNEVKPYVNQTFGDPEYDDDL
                     DAIAEQFVDAIVLPTYKDLQEKNKLLLDAVNQFRQNPSNDNFEKACNLWITAREPWEKS
                     EAFLIGPVANLGLDPNMDSWPLDQNGIVQVLNSQNWDDLEWSGNFDEEDEAIGAAQSVR
                     GYHTLEYLLFKDGQPRTVDGAK"
ORIGIN
        1 gtattaagaa taatttcttc ttttatatat ttaatgtacg caagactatc tgttaacttt
       61 tgtactttga tagcgaaaac gttcgttttt tttagtcatt ttgggcggtc ttcgaaagag
      121 tttgtatcgg aaaggcggtt tttcgtactc cttaagctat ctgattgata agaaagaata
      181 tagaaaaaga aaaaatattt gtggaaagga ttgcaggttc aaaaagtagt tgtatttttg
      241 tgcagtaaaa atgacgaatt aaaacgaacg tttttttagt cattttgttt ctgactacta
      301 tcttttttat tcccaataag ttacaagtaa aaacaagtaa ctttcacccc ttgaaaacgg
      361 gcttttttac tgttcttcac gaacacacat atcatcctta tttataatca cttataaatt
      421 tttactcaag taatactgca gtaacaaact gccattttga gaagaaggct ggggaaatgg
      481 agttaaaaac ggcctttagg tggcaaaaag aagaaaaatt atccataaaa taaaagaaag
      541 tgtgtcgtaa tgaacgatac gccattttgc agggcaactg cactaaaatt cagaaatcgt
      601 ataaaatata ccaaagaaaa aaatagggcc ttatcataca agtttttccc atttcctctg
      661 tcactgtatc actgatttct tttttatcga ttgatattca atctgtttcg ttagtgatat
      721 atgcccgttt tctctatcac tacggtatca ctaccctatc actggcaatt tagatgggaa
      781 acaggaatta cgcttataca catctgtaga ttagcgtatt ataaataaca caaacaataa
      841 acacccaatt tccatcccta taaatcactc gattatttta tgtaaaaacg gctataaaat
      901 aggtaaagcc gggtggtttt cattgttcgg cacggtactt ttgttgccgg acacccccat
      961 gttgccatcc ttaacatccg ggtgtagaga gccggtacac ccggatgtta aggatggcaa
     1021 catgggggtg tttacgaaat tatgtgcttg tctttgctaa aaaagagagg gcttttgtgg
     1081 aatgaagaac cgtatttcgc caatttaaca cctattgcat tcgtttttac atttgtttat
     1141 tcgattattt tatatgcttt ttcaaaggca aaagaaggca atatattggt ttccaatcat
     1201 atgataaaaa cgtcctgtta gaggagtgat agaggcagtg atacaggatg ttttcctcta
     1261 tcactcatct aacgcttgaa tattaatagc tacaaccttc gtagtgatag agtgatagag
     1321 gatttgtaga aacttcgtat ggagatcaca accttggaaa attttgatgc ggttgccctg
     1381 ttgtgaaagt cggggttttg tgcgtaaaaa agaaaaggtg tgcaattttg aacacacatt
     1441 cgtgtagttc aatttgcaca ccttcgtcgt tcatagcaaa tactaaatat taaccgattg
     1501 gacctctcat gcggtcttca aaagcagata gagccgcttt tgccccttct cccattgcta
     1561 tgattatctg tttatagggt acggtcgaga cgtcgcccgc cgcatagatg ccgggaacat
     1621 tcgtccgaca atgcgcatcg attacaatct cacccggttt gttcgtttcg acaacgtcgc
     1681 ggaaaacgcc actattggct gccaagccga tttggacaaa gattccgtcc aggtcgatca
     1741 cccgctccgc atccgtctta cggtctttta cacgaagacc tgttacctta tcaccgtcac
     1801 caaccacttc caaagattgg gaatgcaaga aaacttctac attcggcaag ctctttgctt
     1861 tttcctgcaa cacttgatcg gcttttagct cgtccataaa ttccagaacc gtcactttcg
     1921 aacaaatgcc tgccaaatct atagccgctt cgatacccga atttccaccg ccgacaaccg
     1981 ctacgtgctt acctttatag aacggaccat cgcagtgagg gcaaaaagcg acaccttttc
     2041 cgatatagtc cgcttcgccc ggaacattca acttgcgcca gcttgcacct gtcgccacga
     2101 taagggcagg agcagaaaaa cgttcaccgg tagaagtggt cagaagtttc gccgatccat
     2161 ccagttcgac tttatccaca cggcgatgct ccagtatatc gaccggatag tcgttgatgt
     2221 gcatcagaag gtcgttcgcc aactgctttc cagtagtctg aggaacggaa atcaggttct
     2281 cgataccgac cgtttctttg acctgtcctc cgatacgttc ggctatcact gcgacattca
     2341 agcctttacg tgccgagtag atagcagaag ctgcaccggc aggtccaccc cccactatta
     2401 acacatcata gttcttaaca ggtttttcaa cagagttatc aacaccccct tcattaattc
     2461 cgtattgggc ttcgagtttg gaaagcaatt ctcccaaatc actacgcccc acattgatca
     2521 gtttgccatc ggcaaaaaca gaagggactc cctgtacttt cattgcctca acttcttttt
     2581 ggttgatagc gccatccacc gtttcgtggg tgatccggct attgagagta gccatgacat
     2641 tgagtgcctg cactacatcc ggacaattgg tgcaagtaag agaaacataa gtcgtcagct
     2701 tgatcgggcc gttcaaagct ctgacacggg cacagatact ttcgtccggt atatttttac
     2761 cttttccatc actattcagg acagctaaca acaaggatgt aaactcatgt ccgttaggta
     2821 ctgcacgaaa ccggataccg gtaggcatac cgtcttttac gattgtaaac tgaagtcctt
     2881 cgccatccgc aacgctgcat gacaaatgat ccgagcatga tgccacatca ccaagcaggt
     2941 ctattagctc ctgacggctt tcgtgatcgg gagcgacttg tatatcaaat acatattgag
     3001 ataccagtcc ggagaaaata cccgaaagct ggtctttcat tgctgagtct aacataactt
     3061 tagatcttac caaccaagtc gatgctcggc ttcaaggttg cttcgccttt tttccacttt
     3121 gcaggacaaa cttcgttcgg gtgagaagca acgaactggg cagcttcaac tttacgaagc
     3181 aattcgtctg cattacggcc gataccgtta tcgtggattt cggcaatctt gatctttccc
     3241 tcgggattta ccaggaacgt accgcgataa gccataccct cttcttcaat catcacaccg
     3301 aacgcacgac ttaaagcccc tgtcgggtct gccagcatcg gatatttgat cttacggatc
     3361 gtttcggaag catcatgcca tgctttgtgt acaaagtgcg agtctgtact tacggaatat
     3421 acttcgacac ccatttcctg aaatttgccg tacttgtcag ccatatcgac caattcggtc
     3481 ggacatacga acgtaaagtc ggcaggatag aagaaaaaga tggcccattt gcccttgata
     3541 tcttcgctac ttactgtctt gaaactacca ttctgaaaag cctgtacttt gaattcgggt
     3601 acttgtgaat tgataattgg ttccatgatt tttactattt aatttgttac tactattttt
     3661 tgtttaccct acaaaggtaa atcgtaagat actgattgaa agaatttttc aaattgataa
     3721 tttttatctg ccgatagacg gacttctatc tgcaagcata cttatctact atgacaatag
     3781 gaagcaaagt aatgttttcc ggaacaataa aaatatacct aattgtaggt aaaatacctt
     3841 tcggtcatac catgtgattc tttaattgtt acctttggat gttaacttaa aaatattcga
     3901 agatgagaag agctagtttg tataatacat tttcagcaag tctattgctc gtttgcagcg
     3961 catggctttc ttcatgtgtc tcacaaatac cccttacaaa ggaaaaaccg gtaaacaatt
     4021 ccacttatca agtcgaatat ctgttcgaac acgaagggtg taaggtctat cgtttcatgg
     4081 atatgggaca ttacatctat ttcaccaact gcgagggaga tgttaccagt attgaaagcg
     4141 acagtgtccg cacagtcaac cggatcagcc gtaaaccgat catcatcaaa gagcagacac
     4201 tcgattaggc ttatacggtt atcccgtgtt tcataaagat cgctttcgca ttggccagac
     4261 gctctgctga aagcggttcc acacctttca gcttatagtc caggccttgt gcctcatatt
     4321 tgtaagctcc cattgtatga taaggcagaa gttcggcttt ctggaccacg ttatatgaac
     4381 tgatatattc ggccagcttg ctcaaggctt catcatcgtc cgtcaggccg ggcacgatca
     4441 cgtggcgaat ccatacaggg atgccgcgtt tctccagttc atcaagaaag cgtaaagtat
     4501 tatcgagttt tacggccgtc aaacggggat gaagaccggc gtcgatcgtc ttgatatcta
     4561 acagaaccag atcgacctgt tcgagcacct ccaatgcttt accggaacag atatagccgg
     4621 aagtgtccaa cgccgtatga ataccgttct cacggcaaag gcggaaaaac tctttaagga
     4681 attcaggttg taacaaaggc tcgccaccgg tcacggtaac accaccttta gcgataaaat
     4741 tcttatagcg cagcacttcg gcaagcaacg cttcaggttc cagcagataa ggcgtttcac
     4801 gctttacctc ccaggtatcc ggattgtggc aatacagaca acgaagcgga catccctgca
     4861 tgaaaacaac aaagcgaatt ccgggaccgt caacggtccc gaaactctct aaagaatgta
     4921 tacgccccaa catattaatc aatggacaat tataaactgc tgttgatggt gcgcgagatg
     4981 acgtcaagct gctgttcgcg tgtcagcttc acgaagttga cggcatagcc cgaaacacgg
     5041 atcgtaagct gtgggtattt ctccgggtgc tccatcgcat cgaccaacag gtccttatcg
     5101 aacacgttca cattcagatg ctggccgccg tcaggcgtga aatagccatc caacaggctc
     5161 accaggttat ttatctgaat atcgcgctcc ttacccaacg tagccggtga aacggcgaat
     5221 gtataggaaa taccgtcatg cgcatgctga aaaggcagtt tggcgacaga agccaaagcg
     5281 gcgacagccc ctttcgtatc gcgtccgttc atcgggttgg ctcccggagc aaacggcgta
     5341 ccgcccggac ggccgtcggg agtcgttccg gttttctttc cgtagaccac gtttgatgtg
     5401 atcgtcagga tagattgtgt cggagttgcc ttgcggtatg tctgatgctg gcgcagatat
     5461 tccataaact tctcagtaat gtcgacagca atactgtccg tgcggtcgtc attgtttccg
     5521 aaaggtacat attcgccttc gcgttcgaag tcgacagcca aaccacgttc gtcacggatc
     5581 actttcactt tcgtgtcacg gatggcagcc agcgagtcgg caacgataga aaggccggcg
     5641 ataccggttg cgcggatacg ttccacatct ccgtcatgaa gccccatctc gaatgcttca
     5701 tacgcatatt tgtcgtgcat gtagtgaatg atcttcagtg cattgacata gacttttgcc
     5761 aaccagcgca tcatctgctc gtatttctcc atcacttcgt tgtagtccag atactcgctg
     5821 gtgatcggtt cgaaacgggg agccacctgc acacccgatt tctcgtcacg tccgccattg
     5881 atcgcataca acaagcactt tgccaggttg gcacgagctc cgaaatactg catctgctta
     5941 ccgatcttca ttggagaaac acagcaggcg ataccgtaat cgtcgccata gtccggacgc
     6001 atcagatcgt cgttctcgta ctggatggca gaggtatcga tcgatacttt tgcgcagaag
     6061 tttttccagt tatccggagc attgttgaac caaagcaccg tcagattggg ttcgggtgcc
     6121 gggccgaggt tatacaaggt atgcagataa cggtaagatg tctttgtcac cagcgaacgg
     6181 ccgtcaacac cttgtccgcc cagcgattca gtcacccaaa cagggtcgcc ggagaacagg
     6241 tcgttgtatt ccggagtacg caggaaacgg acaatacgca gtttgataat aaactggtcg
     6301 atcaattcct gtgcctcttc ttccgtcagc ttgccttcgc aaatatcttt ttcgatatag
     6361 atatcgagga aagtagaagt acgtccgaga gacatggctg ctccatcctg atcctttacg
     6421 gctgccaggt aagccagata caagaactgc acggcttcgc gggcatcctt tgccggacgt
     6481 gtcacatcga aaccataacc ggcacacatt ttctcaaatg ctttcagcgc tttgatctgc
     6541 tccgttatct cctcacggct ctgaatgatt tcttctgtca gttcctgtat atcgagacgt
     6601 ttttggaaac gtttcttttc ttcgatcagg atctgggttc cgtacagagg tacacgacgg
     6661 taatcaccga tgatacgtcc gcgtccgtaa gcatcaggca acccggtaat gatggcggaa
     6721 cgacgtgccg caatcatctc gtctgtatag gctgaaaaaa cgccttcgtt gtgcgtcttt
     6781 ctgtatttgg tgaagatctc ttttgtcatc gggtccagat gataaccata ggcttccaga
     6841 ctgttttcga ccatgcggat accgcctttc gggaagatac cacgtttcaa cggggcatct
     6901 gtctgcaagc cgacgattac ttcgttttcc ttatcgatgt aaccgggtcc gtatgtgtca
     6961 atcccctggg gaagcttcgt ttcggcatca tatactcctt tctccctttc aaccttaaac
     7021 atctcggtta gtttgttcca cactttcttc gttttctccg aagagggtac gaggaacgta
     7081 tcgtctccgt tataaggttt gtaattgttc tggataaagt ctcttacatt gatctccttt
     7141 ttccaggttt ctcctttgaa ctgcgcccag ttctcgtttt caaacttcat aagcttatct
     7201 tgtctatttc ggtttaggca cgcaaagata cgtcttttcc ccctatctga aaaggattgt
     7261 aaaggacgag ggatgttaaa ccggagaaaa tacctacaaa tagggataag ggaaataaaa
     7321 acgaagcccc ggcagtacga ataccgccga ggcctgtttt ttgtctgccg tccggtcttc
     7381 acagagggaa aagcagtaga acttttaatt tcattacttt agtattatta atattaaatc
     7441 caaccgctcg ttcgcctgtc gcagggtaat tgaaaccgta gatcaagaaa acctcttaca
     7501 tacggtttca cgcaggttgt ctagaattat ttgattataa aatgtcattg tgcctgtgta
     7561 agggtggttc actaaccacc cttacgatag acagtattgt ttttttagta tcaatcgtta
     7621 cttaacgata gcttttacag cagcttcgcc ttcaacagct acaactacta cgcctgccgg
     7681 agcagcgatt acagcgttgt cagaagagat tactgtgttt gctactacct gacccaagat
     7741 gttgctgatg acaaccttct tgccggcagc acctgcgatt gtcacattgc cttcgccggc
     7801 gagaactttc acttcagata cggctacgcc ttcgttggct gtcggagtag actgggattc
     7861 gatcaggaag cgaacagccg tgttcttgtt tgcttccaga tagaagtagc tattgatcat
     7921 ctgaacatag tttgcacgac cctgacggat cacatattca tcgctaccat cttcagcctt
     7981 gatgatctgg aactggaagt tgtccaaacc gcctttgatt ttcttcggag cattgtcttt
     8041 ttctgctacc aggacagatt ttccgtcaac gacagtgcgc aatgtgtcgg aagagaccaa
     8101 ttcaccagca ttgaagatca gcttagcagc ttcacctttc tggttttcca agttgaagcg
     8161 gtagttgcca cgagcttcgt aatactcaac agagtcttct gcattgtata agaagtgacc
     8221 agccttagaa atgtagaacg taggaatatt cttgtcagat ttaactgtgt ctacccagaa
     8281 tgtcaagtct tcacttgctt ccgtcgcgat gctctggaac gcatcgttgt ccttgttcgt
     8341 caagaaaccg ccacgagtca gtgcgaaaga tacgtgctgc ggaacagctt ctaggctgac
     8401 agccggagtt tcgtcaacca tgaaggtctt caggcctttg tcgatcttat gctccaactc
     8461 gtagttgtat gcatctttcc aagcagtttc tctgtctttc tttaagtcat taaccattgc
     8521 gaaagctcca ttaacatcag ttgtagtcgc agctttgatc aatgatacgg aaccatccaa
     8581 attctgcttg atgatgaatt catctgcaga cacatctgtt gctacttcaa gttcccaagt
     8641 gttgctcaga tatctgtcgt ttgcatcatc aaacgcctta accgcataag tatagaaagc
     8701 gactgtgtct ctttctgttg aagtccgaat acgtttgcca tccaagtaga tgtaattgtt
     8761 caatacatta accggctttt tgctcttaat cagttcaaac tgaaccatgc tgtctgcatc
     8821 ggcataagcc aagatgtctt tgtttggtgc cagattgcca tctacgtctt tctcgccacc
     8881 aacatagaat gccggagcga tatcgctgtt aagggccaat tcgaactgaa ccaagcccat
     8941 gttgtcagct ctgttcacga atgtagcgaa cttgtcttct acagtgtacg gagtcaggac
     9001 gatcttcatg ttcgtcaagt caatagcttc aaaagtaacg acttcatcct ttgaattatt
     9061 tccaactgta ccattgatat attctacata taccttatcc ttgctgcctg ttgccggaag
     9121 tactgtatat acaccatctt cgttttcata cagcgaaaca gtgaaatcaa cttttgtttg
     9181 acggttagcc aaagtgattg tcttgtttgt cttgtcaaca cctgttacaa caaactggta
     9241 catcgggtct gcttcgttga aatcaacagt agaagctaat tcgaaaccag ccggtttatt
     9301 cacagtcaga tattgttcat actcagaagc accttcattc ttttcaccgc ttacaaactg
     9361 gattgtgtaa acagatggtg catcttcttc ctgcaagaag ccaactaaac catcaccatc
     9421 caacagagta gtattagtcg tagtgaaagc caaagcatca gtaacaacag tagttaccat
     9481 gtagttctta ttctgatcag cgatacaacc aatataaaga ccagccttgg cgacgtgctt
     9541 tttagctgca ttgtctgttg cagtaacaaa cacgtgaata ttcttggctt tgatattgta
     9601 tgtttccgga gcagtcactg cattaggaac ttcaactacg aaacaagcat tgcctacgaa
     9661 tacctcttct gcatgagaga agttgtcaga tgtagcagca ccatggaaaa agttcatttc
     9721 actaccctgc atagttatca gttcgtaacc taagccatta tcacggtcag tcgcgttgat
     9781 gtcatagttg cctgtcgggt cgatagcaat gaacgtgcac tgtttgaaca gatccgaatc
     9841 agcaatctta tctgttccga ccaattcttc cggataagaa gtagcaaagt aaacacctgc
     9901 gggaatcttc atgtcgttac ctaggtcaaa atcgttatca acataaaacg ctttcaattt
     9961 cacatcagac agaacatcgt ttgcccaatc caatttcttt ttaggagtga aatcgaagtt
    10021 aaaaccttcg ccagccatag tctcgttcat ggcttcaaca gctacttggt caaccaattc
    10081 ctgggtttta agtttgtaga gatacaactt gcttccagtt aaacctacaa tagaggtaag
    10141 ttctgcacgt gtcaatgaaa caggattcaa ccctgcccct cctgcatagg gatacaatcc
    10201 tgaaccttgc aaaaagcggc ttgtaaaatc attagacagc actgagaatt gagtatacaa
    10261 atgattagcc gcatcaagtt tacaattttc taatttttct ataagatctc ctgattgatt
    10321 tactgtcaac ggcttaccag aagcagcgct agtcaaagtg taataatagc cattaggtac
    10381 accagcaaca tctttcacgg gtgtttcagt aaaagtccaa gtaatctctt tcaacttagc
    10441 accagttgcg aaagctgaaa gattttcacc atagtacttt acagttttac catcctcact
    10501 aactactgct tgcagcaaaa gatcagagcc ttcaagcgta ccatcctcat cagcaaccag
    10561 cacataagga ccgcccgtcc atgcagcatt attggcagga gcagcaacct tctccaattc
    10621 aatcccatta attgtaggag cagtctgcgc ccaagcacta ccacacaacg aacttgtagc
    10681 caacaagccc attgtcaaaa gagtagaaaa cttcttgttc ataatctaaa atgtttaatt
    10741 aataataata tgtatattga atatcgttct tacttcctgt ttaacaggtt tttaccaaat
    10801 tcctgtattt tgacgagata aaacgtacgt tttttcacca tttttcttct catacaccta
    10861 tacttcttat taacaacaat ttatagcacc caaaagtagc taaagccata tataaaagta
    10921 actgttttca atcattcgcc aaacctcttt acatcttcat taaaacaaag attatcagcc
    10981 acatacaaga caaacatcct ttactcgcat cggaagaaaa aatggcaaaa acaactggtt
    11041 tcgtaatttc ctcttggaga agcgtcccct tttgttaaag atatacaaaa tacggagata
    11101 tcgattgctt gctcaataac ggtttcaaga cttgcaaaac cttacattat tatgtatctt
    11161 tacatcaacg tccgttacag acggatcaaa caactataat acattaatat aatatataaa
    11221 aatcgatgct tctgacatcc ccgcctccta tctgttctgt atgaaacaag acagctccaa
    11281 agtcaccact tgcttgagaa ggatcgcaga acaacagatc ggcgacgagg tgaaactgtg
    11341 gcacgtcatc agccctaaat accaagagaa acaaaccgac cagtgtttca tgcctatgta
    11401 acgaccgttt catgccgagg aaacggttgt gccaagccga tgtaattgtt ttggcacagc
    11461 cgaagtagca aacataccct tgcgggaaca agtccaagac tcgacgccga acagattccg
    11521 gacagaagct aatgggaaac ggaaacataa aaaagaagcc tctcttcaca gagaggcttc
    11581 ttttttatat cgaaaataac caataaaaac tttccgatat agttaatcat cttatatgct
    11641 tacataaata gcaaaaggtt ttgatatagc gattatacta atagtgttac tttcttaatg
    11701 acattgcaaa gatacgggca cttcccacct cctacaatac ctatatgtga gtaaaaaaac
    11761 gtcttttact acctaatcaa ggtgatattc aggcgcaata cctacaaatg ggtaacatcg
    11821 gaaccttttt acctactaat tgcgattgca caccgttgac agcccctcta attttgccaa
    11881 aaattaaaaa acgcaatgaa aaggttaact aatttattag caatcactct actcacctct
    11941 tgtgtaacgg catttgcaca ggaacaagaa gaaacaacga cagaaaaatc cgcagtggaa
    12001 caatccgcag acatttatgc cgacggatat aacaagttcc gcttcggcgg atatggggag
    12061 atcctcgcaa actttatgga ctacggcatc aaccgtttcc ggggtacgga caacggaagc
    12121 aagaaagacc atcgcaattc gatctccata ccccgttttg tcttggcttt cgattacaaa
    12181 ttcaattccc aatgggtatt aggagcagaa atagaatttg aggctggagg tacgggtagt
    12241 gcctatgaga tagaaaacac agaaaacgga gaatacgaaa tggaagttga aaaaggcggt
    12301 gaagttgctt tggaacaatt ccacatcaca cgtcttatcc atccggcctt caatgtccgt
    12361 gccggtcatt tgatcgtccc ggtcggtttg accaacgagc atcatgagcc gatcaacttc
    12421 ttcggaactt ctcgtccgga aggcgaaacg accatccttc cttctacctg gcatgaaaac
    12481 ggtatcgaag tgttcggtac gttcggccga ggctacacac gtttcaacta ccaggctttg
    12541 gtcgttgccg gattgaacgc caacgggttc gaccgcaata catgggttgc cggcggcaag
    12601 cagggactat tcgaaacaga taacttcacc tcgccgggct atgtggcccg cctgaactat
    12661 ttaggagtac cgggattgaa aataggcggt tccttctact attgccacaa tacgggagcc
    12721 aattccgaca aaccggaaac atacgtcaaa tatggaaaca tacctttgcg catctatacg
    12781 gccgacctgc aatacaaaaa caaatatgtc accgcacgcg caaacatgat atacggcaac
    12841 ctgagcaaag ccgacgacct cagcagtgtc aacaaccacc aaagcggcgg ttctccttat
    12901 acacagacaa ccccgatcgc caaacgtgcg gtcagctatg gtggcgaagt ggggttcaac
    12961 ctgcgtgcgg tttgtaaaga caacaggaac gtgcccgtca tctatccgtt cgtccgctac
    13021 gaatactaca acccgcagga gaaaggcgaa ggcaagcaca cgatggactt acgcaacaaa
    13081 gtaagcatgt ggacagccgg agccaattgg tatgctttac ctaatcttgt cgtgaaagca
    13141 gactatacaa cacgcaaaat cggaggcggc aaatataaca gcgaaaacga attcagcttg
    13201 gccatcgcct acatcagctg gttcctcagc aaataaaaac aacataaaca atttaatagc
    13261 ttaatcaata aaatgaaaaa gaaaaattat ttctatctgg cagccttatc gctcgccatg
    13321 acattctcga tgggagcatg tagcgacaac aacgacccca atccggatgg tggcggaaaa
    13381 gatccggtca acctggatta cagttctgaa aacgccagtg catggggtaa ctatatgtat
    13441 aacgtagcca tgctgctgaa tgacgacgca accacgctct acaactcctg ggtgaccgac
    13501 tacgtcgatg agcagggttc acacggccca tacgccacga tcttcaaaga ccagactgcc
    13561 ggggcttacc aaagcccgct ctcgtgtatc gaggaaatga tcgaaagcgg tatgtggaac
    13621 atcgccaacg aagtaggtga tgccaagatc aaggacccgt ataccaaata taccagcggt
    13681 gacaaagaag gcggtcttta tgccgtcgaa tcatggtata gctggcattc gcgcgacgac
    13741 tatacgaaca atatcttctc catccgtaac acatactacg gccgcatcga tgacaacgac
    13801 gtgtccaaag tagacggaaa cctgagtgca ttcaactctt acaaagattt cgacgatgaa
    13861 ggagacatcg cagaacactc gctttcaaaa ctgatcgctt caaccaaccc ggatctcgac
    13921 gaagaaatca aaacgctgat tttcgcttct gcaaaggcga tccaggctat tccgcaaccg
    13981 ttccgcaaca acatcgacag cgaagagtcc gttgccgcaa tgaacacttg catggaactg
    14041 gccaacctgt tgttaaatga agtaaaaccg tatgtaaacc aaacattcgg cgatcctgaa
    14101 tacgacgatg accttgatgc aatagccgaa cagtttgtcg atgcgatcgt tcttcctact
    14161 tataaagact tgcaggaaaa gaacaagctt ttgctggatg cggtaaacca gttcagacag
    14221 aacccaagca acgacaactt cgaaaaggcc tgcaacttat ggatcacggc acgcgaaccg
    14281 tgggaaaaga gcgaagcttt ccttatcggt ccggtcgcca acttaggttt ggaccccaac
    14341 atggacagct ggcctttgga ccagaacggc attgtacagg tattgaactc acagaactgg
    14401 gatgacctgg aatggagcgg aaactttgac gaagaagatg aagccatcgg agccgcacag
    14461 agcgtacgtg gttaccatac attggaatat ctcctgttca aagacgggca gccccgcact
    14521 gtcgatggag caaaataaac atgcctctga gacataaaac ttgataatag atcatgacaa
    14581 accttgaaac agcagacaaa tgcccgctgt ttcagggttt cagagtaatt acacaatgcg
    14641 actcgcgtta ttcggaaata aattcagaaa accaataaaa tgatatgaag caatcttacc
    14701 tgttaacatc ctcgctattc ctgctctttg catgcgcagc ttgtgaagag gacgataaaa
    14761 tggatatgga taaaatagat gtcccgaacg gatatgcgct gtcagcaggg acttcaacga
    14821 ttttcctaaa ctcatcggtc gcctacgata cgaacgccga ctggataaca ggagccaact
    14881 cgatccgttt caacaacggc gacggtctct acgacgatgt acgcaccagc aacaatggcg
    14941 acggaggcgg tctcggacct gtttatgccg gctattcctg cggcagttgc catcgcaacg
    15001 caggaaggac caaaccgaca ttgtgggaaa acggcggatc gggcaactac ggtttctctt
    15061 ccatgctggt ctatatctcc cgccgcaacg gtgctttctt ccgcgactac ggacgtgtat
    15121 tgcacgacca agccatctac ggcgtcaaac cggaaggtaa gttgtccgtc acatacgaca
    15181 agcagacttt ttccttcccc gacggagaga cttacgaact atgcaaaccc aattacacaa
    15241 taaccgaatg gtataaagac agtatcgccc cggaagattt gttctgcacc gtacgcatcc
    15301 cgttacgcca cgtcggtatg ggacagatga tggcaatcga ccgcagggaa atcgaagcgc
    15361 tcgctgccaa aagcaattat ccggaatatg gcatcagcgg acgttgcaac tatatcactg
    15421 agaagggtgt caccggtgtc ggcctttcag gaaacaaggc acagcatctt gacctgaccg
    15481 tcgaactggg cttttcaagc gatatgggcg tgacaaacag ccgctatccg gaagagattt
    15541 gcgaagggca ggctcagatc aaccaaggca gcatgatggg actctcgtac gaccagctcg
    15601 acatatcgac cgccgatatg gaagatgtgg acctttacat gcaaagcctc ggcgtaccgg
    15661 cacggcgcaa cataaacgac cctcagg
//
