LOCUS       c00081_gnlPro..        15484 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LIIFOLDO_81.
ACCESSION   c00081_gnlPro..
VERSION     c00081_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:05:23
            Original ID  :: gnl|Prokka|LIIFOLDO_81
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15484
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..414
                     /locus_tag="ctg81_1"
                     /transl_table=11
                     /translation="SESINHTGFVEKIDGDTVFVRITQQSACSGCHAQSMCSASEKKDK
                     IIEVPDRSGRFHVNEEVIICGQNSMGLQAVLLAFVIPLVIVVGAIVIGTNLQWDETTSG
                     LTGLSLLLPYYCILYLMRDKLKRRFIFTLKKLN"
     protocluster    1..15484
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[423:5484]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      424..5484
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15484
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15484
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             424..1356
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 35.6; E-value:
                     3.5e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_2"
                     /sec_met_domain="Fer4_7 (E-value: 9.6e-12, bitscore: 35.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-11, bitscore: 34.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.7e-09, bitscore: 27.1,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2e-10, bitscore: 30.5,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAVGAVFLYAASKKFEVYEDPRIAQVQEVLPGA
                     NCGGCGYPGCAGFAGACVKADSLDGLLCPVGGGPVMAKVATILGKEAGTAEPMVAVVRC
                     NGTCQARPRTNSYDGTKSCAIASTLYGGETNCSFGCLGYGDCVNACAFDAIHINPATGI
                     AEVDEEKCTSCGACVKACPKNIIELRKKGPKSRRIYVSCVNKDKGAAARKACANACIGC
                     GKCAKECPFEAITVTNNVAYIDYTKCRMCRKCVAVCPTGAIHELNFPPRKEAAPAPKAE
                     TVKPAPKAEATVKPEATPKATSEEKTNLN"
     CDS             1368..2699
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_3"
                     /sec_met_domain="Fer4_10 (E-value: 1.1e-09, bitscore: 28.6,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4e-17, bitscore: 52.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.8e-50, bitscore:
                     161.0, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.5e-32, bitscore: 100.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-05, bitscore: 15.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITALATPKQVIIPLSQHIGAPAQ
                     AVVKKGDLVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEETIDRSETLVKECTLSSKEIVDKIAASGIVGLGGATFPTQVKLMPPPGNKAEIVIIN
                     AVECEPYLTSDHSLMLEKGEQILVGVTILMKAVNVNKAVIGIENNKPDAIAHLQKLAVN
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAYAVYEAVQKN
                     KPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKIIGGGPMMGKALIS
                     AEVPVCKGSSGVLLLTTEESVRKPIRDCIRCAKCVGVCPMGLNPTLLMNATEFQNWELA
                     EKNYITDCIECGSCSYTCPANRPLLDQIRLGKGKVMGIIRSRKS"
     CDS             2712..3680
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 8.2e-117,
                     bitscore: 379.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQTGA
                     TVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSAVALILGLLFMLWKKIITWQIPVSILA
                     TVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYGVGIGI
                     LTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             3713..4297
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_5"
                     /sec_met_domain="FMN_bind (E-value: 6e-26, bitscore: 81.1,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTGICLVAGAILAGVNQFTAGPIAVAKATALEEAIKAVAPE
                     FDNKPTEDVYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGEIRVIVGFDMDGK
                     ILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTKDGGDVDAITAATI
                     SSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     CDS             4315..4899
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.7e-69, bitscore:
                     221.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLKILMNGIITENPTFVLLLGMCPTLGTTSSAINGMSMGLATM
                     FVLICSNIVISALKNVIPDLVRIPGYIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGIGIGLGFTMALTLLGACREFLGTGKLFNVTLMP
                     EEYGSLIFVLAPGAFIALGYLVAIVNKLRKA"
     CDS             4912..5484
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg81_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.2e-65, bitscore:
                     210.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALIIFAGIREQLAMTHVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             5510..6550
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 1.1e-49, bitscore:
                     159.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNI
                     VTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQINEE
                     IIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSV
                     FGDDYDTADGSCIRDYINVVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELI
                     NTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRL
                     RERGIQ"
     CDS             complement(6619..9000)
                     /locus_tag="ctg81_9"
                     /transl_table=11
                     /translation="MTNTTLNLEELLCGVNELVDTLWIVTLGNEKVEIVKDSMTPEREG
                     ECLDYTELCQTYIQEYVYPADLGKWEEILSLNSLRQMAASGVANKKFDMRFCNDLLGFE
                     WHEAFIRILKDKSGIPDRVILFSRYVNHCRKAQIVEAAVQTEYDYVVYIEANTNSYVMY
                     TSNRESGTPVPPIASNDYEKEVAEFHHKYVPEDQRDELTRNLSLDHVLSVLRNSREYVL
                     FCQVMENGVFRDKKMRFSFFDKERNILLLTRTDIMEVREEERQRQLLQDALQVAKSANQ
                     AKSDFLSRMSHDIRTPMNAIIGMTTIASMHIDDRERIVDCLKKIMVSSKLLLNLINEVL
                     DMSKVESGHILLTDEEFDMGELLQSVITMVQTSVSQKFQDFRVHLFQVKHEKLIGDVQR
                     IQQVLLNLLSNAIKYTPDYGKITLEIREKPIKNGNYGLFEVTVIDNGIGIKPDFLHKVF
                     EPFERAEDATLRNIQGTGLGMAISRNIAHMMNGEIQVESEYGKGSVFTFTMQLKLQDQG
                     CFEDDHLRDLPVLVVDDDIVCCENACMRINEIGMKGEYAISGEEAIGKVERAHHLNDDY
                     FAVILDLKMPGMDGIETATRIRKVVGRDIPIIILSAYDCPHFEEIAQRAGVDGFISKPL
                     MKSKLFYLMKSFAIKQEEKEEETEKPQYPFGNFEGKRILLVEDNSLNREIATVLLEETG
                     AVVEEAENGLVAVNMVKNSSPGYYDLVFMDIQMPVMNGYDSTRHIRALERPDIKSMPII
                     AMSANAFAEDIKLCKESGMNEHIAKPIDFGKVLEILEKYL"
     CDS             complement(9039..9671)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_10"
                     /sec_met_domain="HAD_2 (E-value: 2.1e-09, bitscore: 27.9,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIKNIVFDLGGVIIDLDRDEPVRRLIEIGVKDADGLIDSYEQK
                     GVFQDLETGKIGVEEFCRYLRKHTGKDLSYEDICWAWFGFIGGVPQYKLDYILKLREKY
                     QVYLLSNTNPIIQLEWAQTKEFTPAGRPLNDYFDKLYLSYEIGVTKPDREIFDRMVLDS
                     GIRPEETLFVDDGKNNIVVGQELGFHTYQPLNGEDWRGRLDEILSKS"
     CDS             complement(9794..11041)
                     /locus_tag="ctg81_11"
                     /transl_table=11
                     /translation="MAKIKPFKGVRPPKEFIEEVASRPYDVLNSQEARAEAEGNEKSLY
                     HIIKPEIDFPEGTDEHDPAVYLKAAANFNNFQEKGWLVQDQKECYYVYAQTMNGKTQYG
                     LVVGAYVPDYMNGTIKKHELTRRDKEEDRMKHVRVNNANIEPVFFAYPDNSELDAIVMK
                     YTAREPEYNFVAKLDGFGHTFWIIDEDKDIARITELFGEMPALYIADGHHRSAAAALVG
                     AEKAKQNPDHKGDEEYNYFMAVCFPANQLTIIDYNRVVKDLNGLTEEQFVERLTKNFVV
                     EEKGSAIYKPGALHNFSLYLGGKWYSLTAKPGTYDDNDPIGVLDVTISSNLILDEILGI
                     KDLRSDKRIDFVGGIRGLGELKRRVDSGEMKVALALYPVTMKQLMDIADTGNIMPPKTT
                     WFEPKLRSGLVIHKLD"
     CDS             complement(11113..12036)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_12"
                     /sec_met_domain="Hacid_dh_C (E-value: 3.2e-36, bitscore:
                     114.5, seeds: 144, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKILVATEKPFAAVAVKGLREVVEGAGMELALLEKYTEKAQLLD
                     AVKDADAVIIRSDKVDAEVLDAAKNLKIVVRAGAGYDNVDLDAATAHKVCVMNTPGQNS
                     NAVAELVFGMLVYGVRNFYNGTSGTELKGKKLGILAYGNVGRNVARIAKGFGMEVYAYD
                     AFCPASVIEADGVKAVASTADLFKACQIVSLHIPATAETKGSINFELMNSMPKGAIVVN
                     TARKEVMDEAGLAKMLEERPDFKYLTDIMPAIHAELAEKYAGRYFSTPKKMGAQTAEAN
                     INAGIAAAKQIVDFLVNGNEKYRVNK"
     CDS             complement(12054..13121)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg81_13"
                     /sec_met_domain="Aminotran_5 (E-value: 7.2e-42, bitscore:
                     133.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKHNFYAGPSILSEYTIKNTAAAVENFAGMGLSLLEISHRSKEF
                     VAVNDEARALIKELLDVPAGYEVVFMGGGASMQFCMVPYNLLNKKASYLDTGTWASNAI
                     KEAKLFGEVDVVASSKDKNYTYIPKGYAIADDSDYFHFTSNNTIYGTEMRKDPDVKQRL
                     VCDMSSDIFSRPIDISKYDIIYAGAQKNLAPAGVTLAIVRVDALGHVDRPIPTMLNYAT
                     HIKKDSMFNTPPVLPIYAALQTLKWYKEQGGIAAMEKKDLENAAILYDEIDRNKLFRGT
                     VAEEDRSIMNVCFVMNDEYKELEDEFSKYATAAGMVGIKGHRSVGGFRASLYNAMPKSS
                     VEALVACMKEFEKQH"
     CDS             complement(13254..14525)
                     /locus_tag="ctg81_14"
                     /transl_table=11
                     /translation="MMSQPLAERLRPKTLDDYIGQKHLVGQGAVLRKMIDAGRVPSFIL
                     WGPPGVGKTTLAQIIANKLDAPFYTLSAISSGVKDVREVIEKAKSNRFFNTVSPILFID
                     EIHRFSKSQQDSLLNAVETGVVTLIGATTENPSFEVIRPLLSRCQVYVLKSLDKNDLLT
                     LLHKAIAEDVVLKDKNIRLTETDAMLRYSGGDARKLLNILELVVSAEESDNIEILDEKV
                     VERLQENPAAYDKGGEMHYDIISAFIKSIRGSDPDGAIYWLARMVAGGEDPEFIARRLV
                     ISASEDIGLANPNALLLANACFDALKKIGWPEGRIILAETTVYLACSPKSNSAYMAIND
                     ALALVNRTGNLPVPLHLRNAPTKLMAELEYGKEYKYAHDYENHFVKQEYLPKEILGERL
                     WKGQENPAEHKLIEQMRRLWGDRF"
     CDS             complement(14578..14673)
                     /locus_tag="ctg81_15"
                     /transl_table=11
                     /translation="MLVYYMGKSVFVVIVLSLCHYFLLFNILFIR"
ORIGIN
        1 agcgaaagta taaatcatac aggatttgta gagaagatcg atggcgacac cgtcttcgtc
       61 cgcattaccc aacaatccgc atgctcggga tgccacgcac agtctatgtg ctcggcatcc
      121 gagaaaaagg ataagatcat tgaggtaccc gatcggtcgg gacggtttca cgtaaacgag
      181 gaagtgataa tatgcggaca aaattccatg ggacttcagg ccgtattgct ggcatttgtc
      241 attcctttgg tgatagtcgt gggggccatc gtaatcggga cgaatctaca atgggacgag
      301 accacgagcg ggttaaccgg tttatcgctt ttactgcctt attactgtat actatactta
      361 atgcgtgaca aactaaaaag acgatttata tttactttga aaaaacttaa ttgataatat
      421 atcatgattt taattgccgt tatttcatta ggagcaatcg gggcggtcgg agcggttttc
      481 ctctacgctg cttccaagaa atttgaagtc tacgaagatc ctcgcatcgc acaagtacag
      541 gaagtccttc ccggggcgaa ctgtggaggt tgcggttatc cgggttgcgc cggattcgca
      601 ggcgcttgcg taaaagctga ctcattagac ggattgctct gccccgttgg tggtggcccg
      661 gtcatggcca aggtcgctac aatactgggt aaagaggcgg gtacagccga acccatggta
      721 gccgttgtcc gttgcaacgg aacttgtcag gcccgcccac gtacaaactc ttatgatgga
      781 acgaaaagtt gcgccatcgc ctctaccctt tacggaggcg agacgaattg ttctttcggt
      841 tgcctaggtt atggcgactg cgtgaacgcc tgcgctttcg acgccatcca catcaacccg
      901 gctacgggaa tcgccgaggt agacgaggaa aaatgtactt cctgtggtgc ttgtgtgaag
      961 gcttgcccga agaatatcat cgagctaaga aagaaaggac ctaaatcacg ccggatttac
     1021 gtgtcttgcg taaataagga caagggagcc gccgctcgca aggcttgtgc caacgcttgt
     1081 atcggctgtg gcaaatgtgc caaggaatgt ccgttcgagg cgatcaccgt aacaaataac
     1141 gtggcttata tcgattatac aaagtgccgg atgtgccgta aatgcgtggc tgtatgtccg
     1201 acaggagcta ttcatgagct gaatttccct cctcgcaagg aagccgctcc cgctccgaaa
     1261 gcggagaccg tgaaaccggc gccgaaggca gaggctaccg tgaaaccgga agccacaccg
     1321 aaagctacaa gtgaagaaaa aacaaatcta aattaaaatc taatagtatg ctaaggacat
     1381 ttcgaatcgg aggtatacat ccccccgaga ataaactgtc tgccggtaag aaaattacgg
     1441 ctctcgctac gcctaaacag gtgattatcc ccctcagcca gcatatcggt gccccagcgc
     1501 aggccgtggt gaagaaaggg gatctggtaa aggtgggtac attgctagcc aaggcgggtg
     1561 gtttcgtatc agcgaacatc cactcttccg tatccggcaa agtgaacaag atagataacg
     1621 ctctcgacgc tagcggatac aaacgtcccg ctatctatat agatgtggaa ggtgatgaat
     1681 gggaagagac gatcgaccgc agcgagacct tagtgaagga gtgcacgctg tcttccaagg
     1741 aaatcgtgga taagatcgcc gcttccggta tcgtcggtct gggtggagcg actttcccta
     1801 cgcaggtgaa attgatgccg cctcccggaa acaaggcaga gatcgtaatc atcaacgccg
     1861 tggagtgtga gccttatctt acttccgacc attcgttgat gctggagaaa ggcgagcaaa
     1921 tcctagtcgg tgtcacgatc ctaatgaaag cggtcaacgt gaacaaggcc gtgatcggta
     1981 tcgagaataa caagccggac gctatcgccc atctgcaaaa gttggcggta aattataaag
     2041 gtatagagat catgccgctt aaggtacaat atccgcaagg aggcgagaaa caattgatcg
     2101 acgccgttat tcgccgtcag gtaaaaagtg gtgcgcttcc tatctcggcg ggtgccgtgg
     2161 tacagaacgt aggaactgct tatgccgttt acgaggcggt acaaaagaat aaaccgttgt
     2221 tcgagcgtgt ggtgacgatc acgggtaagg cggtagctaa tccttccaat ttcttggttc
     2281 gtatgggaac accgatcagt tgcttgatcg aggccgcagg tggcctgccc gagaatacgg
     2341 gtaagattat cggtggcgga ccgatgatgg gtaaagcgtt gatcagcgcc gaggtgccgg
     2401 tttgcaaagg aagctccggt gttttattac tgacaacgga ggaatctgtc cgcaagccga
     2461 tccgggattg catccgttgc gccaaatgcg taggtgtctg cccgatggga ttgaacccta
     2521 ccctattgat gaacgccacg gaattccaga attgggaatt ggcggagaag aactatatca
     2581 ccgactgtat cgagtgcggg tcgtgtagtt atacctgtcc ggccaaccgt ccgttgctgg
     2641 atcagatccg gttgggtaaa ggaaaagtta tgggtattat ccggtctaga aagtcataaa
     2701 acaagagcaa catggaaaat aatttatacg tatcgccctc gccccacatc catggtggcg
     2761 acagcataag caaaaatatg tatggtgtac tgattgccct tatcccggct ttcttggtat
     2821 ccctttattt cttcggtctg ggagcgttga tcgttacggt cgtatcggtt ctggcctgta
     2881 tgatattcga gtatttgatc cagcgattcc tgatgaaaaa ggaaccgacc ctttgcgatg
     2941 gctccgctat cctgacgggc gtattgctgg ccttcaacct accttccaac cttccggtct
     3001 ggatcattat catcggagcg ttggcggcga tcggcatcgg caagatgtct ttcggtggat
     3061 taggtaataa tattttcaat ccggcgttgg tcggacgtgt attcttattg atctccttcc
     3121 cggcgcagat gacgacttgg ccggtggtag atgccttgaa cgttttcccg atgacttata
     3181 cggacgccca gaccggcgcg acggtactgt cgttgatgaa cgagggcgtg accgagcttc
     3241 cgtcttacgg gaatatgctt gtaggggcta tgggaggtag tctcggtgaa gtgagcgccg
     3301 tggccttgat cctcggtctt ttattcatgc tatggaaaaa gatcatcact tggcagatcc
     3361 cggtatccat cttggctacc gtattcgtat tcacgggcat catgcacttg gtgaatccgg
     3421 tacaatacgc cagcccgttc gttcatttat tatccggtgg tttgttatta ggctccatct
     3481 ttatggcgac cgactacgta acctcgccga tgagcaagaa cggaatgctt gtctacggcg
     3541 tgggaatcgg aatccttacc acggtgatcc gtttgttcgg gtcttacccg gaaggtatgt
     3601 cgttcgctat cctgatcatg aacgcattta ctccgctaat caacagctat atcaaaccta
     3661 aacatttcgg aggaaagtaa gcatggcaaa attaaaatca acattaccca atatgctcct
     3721 ttcactaaca ggcatttgct tggtagcagg ggcgatccta gccggagtga accagtttac
     3781 cgccggccct atagcggtag ccaaagcgac cgccttggag gaagcgatta aagccgttgc
     3841 tcccgagttc gacaacaaac cgactgagga cgtctatatg gccgtctcct ccgatggtga
     3901 ttccctcaag atttatcctg ccaagaaagg cggacaagtc gttggcggag ccgtagagag
     3961 taatacgaaa aaaggcttta gcggtgagat acgggttatc gtaggtttcg atatggatgg
     4021 caagatcttg aactattccg tattgcaaca cgccgagact ccgggcttgg gagccaagat
     4081 gcaagaatgg ttccgtgcgg acaagaacaa gcaaagtgtc ttgggacgta cgattccgga
     4141 cggaggctta aaagtaacaa aagatggtgg cgacgtggac gctatcacgg cagcgacaat
     4201 ctccagccgt gcgttcctcg atgccgtgaa ccgtgcgtat agcgcattcg ctggcgtaga
     4261 cggactaacg ggtgccactt caactgataa caaataaaaa gggaggacag aacaatgagt
     4321 aatctaaaaa tattgatgaa tggtatcatc acggagaacc cgacatttgt attactgtta
     4381 ggtatgtgtc ctaccttggg aacgacctct tcggccatca acggcatgag tatgggattg
     4441 gctacgatgt tcgtattgat ttgctcgaat atcgtgattt ccgccttgaa aaacgtaatc
     4501 cccgacttgg tgcgtatccc gggatatatc gttgtgatcg cgacgttcgt gaccgtagtg
     4561 cagatgtgca tggaagcgtt cgtcccggct ttatacgcta gcttgggatt atttatcccg
     4621 ttgatcgtgg taaactgtat cgtactagga cgtgccgagg ctttcgctgc gaagaacggc
     4681 gtaatcccat ccgctttcga cggaatcggt atcggactgg gctttacgat ggctcttacg
     4741 ctgctgggcg cttgccgtga gttcttggga accggtaagt tattcaacgt aaccttgatg
     4801 cccgaggaat atggttcgct gatcttcgta ttggctccgg gagcgtttat cgccttgggt
     4861 tatctggtag caatagtaaa caaactgcgt aaagcataat aaacggatca tatggaatat
     4921 atattgatat ttatcgccgc cgtattcgtt aataacgttg tactggcaca gttcttggga
     4981 atttgtccgt tcttgggggt atctaagaaa gtggagactg ccgcaggcat gggagccgcc
     5041 gttacgttcg tgcttacgat cgccacgatt gttacattcc tcgtgcaaaa atacatattg
     5101 gacgctttcg gattagggtt catgcagacg atcagtttca tcttgatcat cgccgccttg
     5161 gttcagatgg tggaaatcat attgaagaag gtctctcccg ccctttacca ggcgttgggc
     5221 gtattccttc cgttgatcac cacgaactgc tgtatcctgg gtgtagctat ccttgtaatc
     5281 caaaaagagt ataatttatt ggaatctgtg gtatatgcta tctcgaccgc tattggattt
     5341 gcgctagctt tgattatctt cgcgggtatt cgggagcaac tagccatgac gcatgttccg
     5401 gaaggcatga aaggcactcc tatcgccttg ataacggccg gtttgctagc tatggctttt
     5461 atgggattct cgggtatcgt ataacaaact tatctaaatg aacactagaa tgaaaaagaa
     5521 gattttagta gcgggcggaa ccggttatat cggctcacac accacagtag aattgcagaa
     5581 cgccggatat gaggtagtca ttatcgacga tttgtcaaac tcgaatatcg aggtgctcga
     5641 tggtatcgag aaaatcacgg gcatccgtcc ggagtttatc caattggatc taaaggataa
     5701 ggaaggtact cgcaaggcat tggaagctca tccgggcatc aaaggcatta tcttgttcgc
     5761 cgctagcaag gcggtaggag aatccgtaca gcagcctttg aagtattatc gcaataatat
     5821 tgtcactttg gtgaacttgt tggagatgat gcctgaattc aatatcgaag gtatcgtatt
     5881 ctcttcctct tgtacggtat acggacaacc ggatccggag aacttgccgg taaccgagaa
     5941 cgccccgatc aaacccgcta tgtctcctta tggaaacacg aagcagatca acgaggagat
     6001 tatccgggat acgatccatg cgggagcgcc tttcaagagt atcatcttgc gctacttcaa
     6061 cccgataggc gctcacccaa gcgcagagat cggcgagttg ccgaatgggg ttccccagaa
     6121 cttgatcccg tacttgacac agacggctat gggtatccgc aaggaattaa gcgtattcgg
     6181 cgatgattat gatacggcag acggctcttg catccgtgac tatatcaatg tcgtagactt
     6241 ggcgaaagca catgtaatcg ctatggaccg tatgcttgag aataagtctg atgagcatat
     6301 cgagatattc aacctaggta ccggtaatgg tgtttctgtc cttgaactga tcaatacctt
     6361 cgagcagaca acaggcgtta aggttccgca caagatcgtg ggccgtcgtg aaggtgatat
     6421 cgagaaggta tgggccaatc cggagcatgc gaataaggta ttaggctgga ccgccaagga
     6481 gactttagcc gacaccctgc aatccgcatg gaactggcag aaacgtttga gagaacgtgg
     6541 catccagtaa ataacacaaa aaagaggccg tatctgatag cgcttagcta agatatggcc
     6601 ttttttatat ccttatatct acaagtactt ctctaagatc tcaagaacct tcccgaaatc
     6661 gatcggctta gcgatatgct cattcattcc ggattcttta cacaacttga tgtcttccgc
     6721 aaatgcgttc gcagacatgg ctattatcgg catggacttg atatccggac gttctaatgc
     6781 ccgaatatgg cgagtagagt cgtacccgtt catgaccggc atctggatat ccataaatac
     6841 caagtcataa tatcccggac tagagttttt taccatattc accgcgacaa ggccattttc
     6901 cgcctcctct accaccgcac cggtctcttc tagtaacaca gtcgctattt ccctattcaa
     6961 gctattatct tccaccagca agatccgctt accctcaaag ttaccgaaag gatattgagg
     7021 cttctccgtc tcttcctctt tttcctcttg cttgatagcg aaacttttca tcaaataaaa
     7081 taacttggat ttcatcaacg gcttacttat gaatccatcg acaccggctc gttgggctat
     7141 ctcctcaaaa tgcggacaat cataagcgga aagaataatg atcggaatat cccggccaac
     7201 gacttttcgg atacgggtag cggtctcgat tccatccatt cccggcattt tcagatcaag
     7261 gataacggca aaatagtcat cattaagatg atgtgccctc tctactttcc cgatagcctc
     7321 ctcaccagaa atggcatatt cacctttcat accgatctcg ttaatcctca tacatgcgtt
     7381 ctcgcaacac acgatatcat cgtctaccac gagaaccggt aaatccctta aatgatcatc
     7441 ctcaaagcac ccttgatcct gcaatttcaa ctgcatcgta aatgtaaaaa cggaaccttt
     7501 gccatattca ctctccacct gaatctcacc attcatcata tgagcgatat tacggcttat
     7561 tgccatgcct aagccggttc cttgtatatt ccgcagggtt gcgtcttccg cacgttcaaa
     7621 tggctcgaaa accttgtgta agaaatccgg ctttatcccg ataccattgt ctataaccgt
     7681 aacctcaaat aaaccataat taccattttt aattggcttt tcccgtatct caagtgttat
     7741 tttcccatag tccggcgtat actttatggc gttcgacagc aaattcaaca atacttgctg
     7801 aatccgttgc acatcgccaa tcagcttttc atgtttgact tgaaacaagt gaacccggaa
     7861 atcctgaaac ttctgactga ccgaagtctg aaccatagta attacgcttt gcaataactc
     7921 gcccatatcg aactcctcgt ctgtcagcaa aatatgtccg ctctctacct tagacatatc
     7981 caagacctca ttgatcaagt tcaataacaa tttggaagaa accataatct tcttcaagca
     8041 atccactata cgctcccgat cgtcgatatg catactggcg atagtggtca taccgataat
     8101 ggcattcatc ggagtacgta tatcatggct catacgggat aagaaatccg atttagcctg
     8161 atttgccgat ttagccactt gtagggcatc ttgaagtaat tgcctttgcc gctcttcctc
     8221 acgaacctcc ataatatcgg tccgggtcaa aagaagtata ttcctctcct tatcgaaaaa
     8281 gctaaaacgc atcttcttat ccctaaaaac gccattctcc atcacctgac agaacaagac
     8341 atactcacgg gaatttcgta agacagataa gacatgatct agggaaagat ttcgggttaa
     8401 ctcatctcgc tgatcctccg gcacatattt gtggtggaac tcggctacct ctttttcata
     8461 gtcattactc gctatcgggg ggaccggcgt cccactttca cgattggaag tatacatgac
     8521 atagctattc gtgtttgcct ctatataaac gacataatca tactcagtct gaacggcagc
     8581 ctctacgatc tgtgccttgc gacaatgatt cacatagcgg ctgaaaagaa tgacacgatc
     8641 cggaattcca ctcttatctt tcaagatacg aataaaagcc tcatgccact caaaacccaa
     8701 caaatcatta cagaaacgca tgtcgaactt cttatttgct acgccgctag ccgccatttg
     8761 ccgcaatgaa ttcaaggata agatctcctc ccatttccct aaatccgcag gatatacata
     8821 ttcttgaatg taagtctggc aaagttctgt ataatccaaa cattctcctt ccctttcggg
     8881 agtcatcgaa tctttgacta tctcaacctt ttcattacct aatgtgacga tccaaagcgt
     8941 atcgactagc tcgtttacac cacagagtag ttcttccaaa tttaaagtag tatttgtcat
     9001 tttcaatgat atagatttaa ttaagaggaa tagagatcct atgattttga gagtatttca
     9061 tcgagcctcc ctctccaatc ctctccattc aaaggctgat aggtatggaa ccccagttcc
     9121 tgccccacta cgatattatt cttaccatca tctacaaata atgtttcctc tggtctgatt
     9181 cctgaatcca agaccatgcg atcaaaaatt tcacgatctg gcttcgtgac accgatttca
     9241 taagagagat acaatttatc gaaataatca tttaatggac ggcccgccgg cgtaaactct
     9301 tttgtctgtg cccattcaag ctgtatgatc ggatttgtat tgctcaataa atagacttga
     9361 tatttctcac ggagttttaa tatgtagtcc aatttatatt ggggaacgcc accaatgaag
     9421 ccaaaccaag cccaacaaat atcctcataa gaaaggtctt tacccgtatg cttccgtaaa
     9481 tagcgacaaa actcctctac tccgatcttt ccggtctcca gatcttgaaa aacccctttt
     9541 tgttcgtaag aatctatcaa tccatcggca tctttgaccc caatctctat taaacgacga
     9601 acaggttcat cccggtccaa atctatgata acgcccccca gatcgaatac tatatttttt
     9661 attttaccca ttgcgatact atttaagtcc taaagataca atttattccg tatatctagg
     9721 ttacaaggat aaaaaagggt ataatcttca acgattatac cccaatccaa agctatattt
     9781 atgtatataa gacttaatcc aatttatgga tcaccaaacc ggagcgaagc ttcggttcga
     9841 accacgtcgt cttcggcggc ataatattac ccgtatcggc gatatccatc aattgcttca
     9901 tcgtaacggg atacaaagcc aaggcaacct tcatctcacc gctatccaca cggcgtttca
     9961 attcacccag gccacggata cctcccacga aatcgattcg cttgtccgaa cgtaaatcct
    10021 taatgcctaa aatctcatcc agaatcaagt tcgaagagat cgtgacatcc aatacgccta
    10081 tcgggtcatt gtcatcgtac gtaccgggct tagcggtcaa agaataccat ttccctccta
    10141 aatacaggga gaaattgtgc aaggcacccg gtttgtaaat agcagagccc ttctcctcta
    10201 ccacgaagtt tttcgttaat ctctcaacga attgttcctc ggtcaagccg ttcaagtctt
    10261 ttaccacacg gttgtaatcg ataatggtca attggttggc cgggaagcaa acagccatga
    10321 aatagttata ctcctcgtct cccttatgat ccgggttttg cttggccttc tccgctccta
    10381 ccaaagcagc ggcggcggaa cgatgatgtc cgtcggcaat atacaacgca ggcatctccc
    10441 cgaataactc cgtgatgcga gcgatgtcct tatcctcatc gataatccag aacgtatggc
    10501 cgaaaccgtc taatttcgcc acgaaattat attcaggctc acgagccgta tatttcatta
    10561 cgatagcgtc taactctgag ttgtcgggat aagcgaagaa taccggctcg atattagcgt
    10621 tgttgacacg tacgtgcttc atgcgatcct cctccttgtc acggcgggtc agctcatgtt
    10681 tcttgatcgt gccattcata taatcgggaa cataagcccc gactaccaac ccatattgag
    10741 tcttgccatt catagtttgg gcataaacat aatagcattc tttctgatcc tgaaccaacc
    10801 aacctttttc ctgaaaatta ttgaaattgg cggcggcctt caggtaaaca gccggatcat
    10861 gctcatccgt cccttctggg aaatcgattt ccggtttaat gatatggtaa agggatttct
    10921 cgtttccttc cgcttccgca cgagcttctt gcgagttcaa tacgtcatag gggcgggaag
    10981 ccacctcctc tataaattct tttggtggac gaactccctt gaaaggtttt atttttgcca
    11041 tggtaattaa atctaattgg tttatgtatc aatgtagaga cggggcgtac ccgtctctac
    11101 aaccggatat tctcatttat taacccgata cttttcattg ccattcacca agaaatcaac
    11161 gatctgcttg gcggcggcga taccagcgtt gatattagcc tcggcggtct gggcacccat
    11221 ctttttcggg gtgctgaaat aacgaccggc atatttttcg gccaattccg catggatagc
    11281 gggcataata tctgtcaagt acttgaaatc cggacgctct tccaacatct tagcgaggcc
    11341 agcctcatcc atcacctcct tacgagccgt attcactacg atagctccct tcggcatgga
    11401 attcatcaac tcgaaattga tagaaccctt cgtctcggcc gtagccggga tatgcaagga
    11461 aacgatctgg caagccttga acaagtccgc cgtagaagct acagccttca caccatcggc
    11521 ctcaatcacg gaagccggac agaacgcatc ataagcgtaa acctccatac cgaagccttt
    11581 agcgatacga gccacgttac ggcccacgtt tccataagcc aagataccca atttctttcc
    11641 tttcaactct gttccggaag ttccgttata gaaattacga accccgtaca ccaacatacc
    11701 gaataccaat tcggcgacag cgttagagtt ttgtcccggc gtattcatca cgcatacctt
    11761 atgggcagta gccgcatcca agtccacgtt atcatacccc gcaccggcac gaaccacgat
    11821 cttcaggttc ttagcggcat ccaatacctc agcgtccacc ttatcgctac ggataatcac
    11881 ggcatcggca tccttaaccg catccagcaa ttgcgccttc tctgtatatt tctccaaaag
    11941 agccagttcc ataccagcgc cttccactac ctcccggaga cctttcacag cgacagcggc
    12001 gaaaggtttc tctgtagcaa ctaatatctt tgccatgtct gaatcctcct tgattaatgt
    12061 tgtttctcga actctttcat gcaagctacc aaagcctcca cgctgctctt cggcatcgcg
    12121 ttataaagag aggcacggaa accacctaca gaacggtgtc ccttgatacc taccatacca
    12181 gcggcagtag catatttact gaactcgtcc tccaactcct tatactcatc attcatcacg
    12241 aaacaaacat tcatgatcga acgatcttcc tccgctaccg taccacggaa caacttattg
    12301 cgatcgatct catcgtataa gatcgccgcg ttctcaagat ccttcttctc catagcggcg
    12361 ataccacctt gttccttata ccatttcaag gtctgtaaag ccgcgtaaat aggcaataca
    12421 ggaggtgtat tgaacatgga atccttttta atatgggtag cgtagttcaa catggtcggg
    12481 atcggacggt ctacatgtcc taaagcgtcc acacgaacga tagccaaagt cacgccggca
    12541 ggagccaagt tcttttgagc acccgcatag ataatatcat atttggaaat atcgatcgga
    12601 cgagagaaaa tatcggaaga catatcgcaa accaaacgtt gcttcacatc tggatcttta
    12661 cgcatctctg ttccgtaaat cgtattatta gaagtaaaat ggaaataatc cgagtcatca
    12721 gcgatcgcat aacccttcgg gatgtaagta tagttcttgt ctttggaaga agcgacaaca
    12781 tctacctccc caaacaactt agcttccttg atagcgttcg aagcccatgt gccggtatcc
    12841 aaataagagg ctttcttatt caacagattg taaggaacca tacagaactg catgctggcg
    12901 ccaccgccca tgaatacaac ctcatagcct gccggaacat ccagtaattc cttgatcaac
    12961 gcacgtgcct cgtcgtttac ggctacaaac tccttacttc tatgagagat ctcaagaagt
    13021 gataacccca tacccgcaaa attttctacc gcagcggctg tattcttaat tgtatactcg
    13081 ctcaagatag aaggacctgc ataaaaattg tgcttcttca taccaatgtc tttttagaat
    13141 gttattataa ataaagtaac tattttttca aaaataggcg gctaatgtaa ctattttttc
    13201 tcatttgccg acacttttcg agcatttttt aatttacaat cagaatatgt caattaaaaa
    13261 cgatctcccc aaaggcgcct catttgctca attagtttgt gctcggccgg attttcctgt
    13321 cctttccaca aacgttcgcc caaaatttcc ttcggaagat actcctgctt tacaaaatga
    13381 ttttcgtagt cgtgcgcata tttatattcc ttgccatact ccaattcagc cattaatttg
    13441 gtaggcgcgt tgcgtagatg aagcggtacg ggtaaattcc cagtccggtt aacaagtgcc
    13501 aaagcgtcgt tgatcgccat ataggccgaa ttacttttcg ggctgcaagc cagataaacg
    13561 gtcgtctcgg ccagaatgat ccggccctcc ggccagccga tcttcttcaa ggcatcgaaa
    13621 catgcgttcg ccagcaaaag cgcattcgga ttcgccaatc cgatatcctc agaagcggag
    13681 atcaccaacc gccgtgcgat aaactcaggg tcttctcccc cggccaccat acgggcgagc
    13741 cagtaaatgg cgccatcggg atcgctaccc cggatcgact tgataaaagc ggagattata
    13801 tcgtaatgca tctcccctcc cttatcatac gccgcagggt tctcctgcaa cctctccact
    13861 accttctcat ccagaatctc aatattgtca ctctcctcgg cagacaccac cagttccaga
    13921 atattcagca acttccgggc atctcctccc gagtaacgta acatggcatc cgtttccgtc
    13981 agccttatgt ttttatcctt cagaacgaca tcctcggcga tcgccttatg caatagcgta
    14041 agcaagtcat tcttgtccag cgatttcaac acgtacacct gacaacggga taacaaagga
    14101 cggattacct cgaacgaggg attctccgtg gttgccccaa tcagcgtcac cacgcccgtc
    14161 tccacggcgt tcagcaatga gtcttgctgc gacttactga atcggtgtat ctcatcaata
    14221 aacaatatcg gcgataccgt attgaagaag cggttgctct tggccttctc tatcacctcc
    14281 cgcacgtcct tcactcccga actgatcgcg cttaacgtat aaaaaggcgc atccaactta
    14341 ttcgctatga tctgcgctaa ggtagtcttc ccgactcccg gcggccccca caatataaaa
    14401 gagggaaccc gtcccgcatc aatcatcttc ctcaacacgg ctccctggcc taccaggtgc
    14461 ttctgtccga tataatcatc caacgtcttc ggacgtaatc tctctgctaa tggttgactc
    14521 atcatggaag caaaagtcgg atattttatt tacttttcaa aggataagtc aagaaattta
    14581 tcgtataaaa agaatgttaa acaacaggaa atagtgacat aatgaaagaa caatcactac
    14641 aaatacactt ttacccatat aatatactaa cattatgaca atgaaaattt aacattccct
    14701 taattcccta tcctttttat cccatacttt tagcgatatc ttcttaacac attatacctt
    14761 ctttcttgaa gcattaaata tctatcaact ggtgcatgat cgtccaacag ttggtgcatg
    14821 atcatgcaac gtctgttaga tgatcatgca ccaattgtta gatgatctat atttccatat
    14881 aaaaccaata agccttccaa ggaaatggga taagggaagc tatcaaaaca tgtaagatat
    14941 ataacaaaaa aagatgcccc tccataatcg gagaggcacc ctatacatta tattatatat
    15001 gttagattag cgagttccgc cagcccacca tacaggctct gaatatacgt attgaccgtc
    15061 gccataagcg gcttttactt ccggatttga taccacgtca ctattaccat aaggcatacg
    15121 aagagggaat tttttcgtat tcgccaatgt cacgaaattc tctcctaatc ctttcattct
    15181 acggatatca ttaaaagtct cggtagcctc tcccgatgcc ccccacaaag ccagatattt
    15241 ctggatcatg gtctctttca aaggatttac agcaaacaac ggtttaactt ggttatcgaa
    15301 atatgtattg gccgtctcct ctgtcatttt ttctgaattc acgaccattt tgctacccat
    15361 ataagtgata gcagaagaga cacttctctc agcatttgcg attccggcag ctaccgcctc
    15421 tttcaacgct ttctcggcgt cagacgtacg gtttaagcga cataacgcct cagcttgcaa
    15481 gaat
//
