LOCUS       gnlProkkaOMJBEFCL_24   15034 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMJBEFCL_24.
ACCESSION   gnlProkkaOMJBEFCL_24
VERSION     gnlProkkaOMJBEFCL_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 16:00:21
            Original ID  :: gnl|Prokka|OMJBEFCL_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15034
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15034
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4623:5034]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4624..5034
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15034
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15034
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(2..109)
                     /locus_tag="ctg24_1"
                     /transl_table=11
                     /translation="MGYFLPLTITEHINGNINCLTERVLARQSLACDVIS"
     CDS             complement(161..682)
                     /locus_tag="ctg24_2"
                     /transl_table=11
                     /translation="MCQIDIGSRHHTHIRFLYFGRTYFHKLATLQYTEQTCLGRHRQLP
                     YFIKENSTTVGFAKVPFPFANRTGKRTLLMPEQFGINRALRNSTTVDSNILSVLPPAIL
                     MNNLRKTFFSDSTFSGNQHRQIGRSYLNGNIYGAQQCLGISDNTETLLHLLYLRFCHYF
                     LLIFVYCIQL"
     CDS             complement(713..1270)
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MYVIVILANRRLHGMNDRRYRRLVCRHYRSSNHRSHLSYLPHLSG
                     TFRHQVVHHLLQLRHFLAHIKQNRIKNLPFALKAFTLTRSHQRGKTLRILCGKIILQDS
                     SRNLPVGFNDRYLLGDVLQLTHVSGPRVSQQLFLRILRQLNSRHPVFLCKVCGKLTEQQ
                     KYIVTTFTQRRYLDRHRIQPVI"
     CDS             complement(1304..1489)
                     /locus_tag="ctg24_4"
                     /transl_table=11
                     /translation="MTTNGKPNSSKGRIIFLIQFIFFYFSIKCTLGNIQVLGRTLPLSM
                     MPLKCLAYHFFLHFVQ"
     CDS             1599..1955
                     /locus_tag="ctg24_5"
                     /transl_table=11
                     /translation="MATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQA
                     VSADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSK
                     EITDQIFNATVANW"
     CDS             1961..2722
                     /locus_tag="ctg24_6"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTVPEEVTARTSFDYSMDYTSFILEETPATEQPAEETPKLKGFDFIEKSESD
                     SPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKALEII
                     KKLSLKYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             2751..3116
                     /locus_tag="ctg24_7"
                     /transl_table=11
                     /translation="MLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKTTDFLEKE
                     TWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEAPQSEAPAA
                     TTPAETPAPAAEAPAAE"
     CDS             3270..4661
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 97; E-value: 1.6e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg24_8"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSFVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             4624..5034
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_9"
                     /sec_met_domain="PqqD_RRE (E-value: 6.1e-10, bitscore:
                     30.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.1e-16, bitscore: 52.5,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVISWKSLIFRNNRKSGYRMMEIPEGKVSLLDAVPVRCGHITTEW
                     EGECAVLAYPRFKYEWMRRFLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLA
                     RHFGEEENYIPRVTAYVMQLRKDGFIQLTIRN"
     CDS             complement(5042..6055)
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MSTTALAQTDVTTGVMRGKDYGVTYMLPKTEIEIVLQATKHTYTP
                     GEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKMKDKTVAPLMELT
                     EDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSAKMAELVAKEIYS
                     IRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKKEPKTFTIRLTPK
                     EMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKKKVDGVAYNLPGK
                     AQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTATGGLIKVDRE"
     CDS             complement(6162..7196)
                     /locus_tag="ctg24_11"
                     /transl_table=11
                     /translation="MLIGTYTNGSSKGIYTFRFNQETGTAVPLSSAALPNPSYLVPSED
                     GEFVYAVSEMNDSTAALSSLAFDRETGELRLLNTVPTFGADPCYVATNGREVLTANYSG
                     GTMSVFPLQKDGTLAPADTLFQGSATGPDAIRQATPHIHCTVFSPDGKYIFATDFSADR
                     ILRFVMHPDDPIPHASLEAVGIEADSGPRHLTFSPNGKFAYLITELSGKVIAFSYDDGC
                     LEQIQTITADTVAARGSADIHLSPDGKYLYASNRLKEDGIAIFAVNPENGTLAKVGYQP
                     TGIHPRNFNITPNGKYLLAACRDSNVIQVYKRNEVTGLLEDTHQDIVVDMPVCVQFVSS
                     VNNL"
     CDS             complement(7391..10363)
                     /locus_tag="ctg24_12"
                     /transl_table=11
                     /translation="MEDIFSKRKTLRTIKADTSDYFIPLFHTLAVFLSTKETIITKRFL
                     EHIMKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFNKNGVKDVYEDP
                     SAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLWKDGIGAIDEHL
                     NGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNEGIRGVESYRAT
                     NFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGES
                     PYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQMSPREVENIHIY
                     PFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVVSDSDAVEYLYT
                     KHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEEVINDRVRDILR
                     VKFLIGLFDAPYQTDLAGADREVEKEENEAIALQASRESIVLLKNAGELLPLDINSTKK
                     IAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGCDLVDAHWPESE
                     IIDYPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLDLPGRQLQLLQA
                     IQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGMALADILFGDYNPGGKLT
                     VTFPKTVGQIPFNFPCKPSSQIDGGKNLGPTGNMSRINGALYPFGYGLSYTTFEYSDLD
                     ITPRVITPNESATVHLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNLAGFQRIHLEPG
                     EAQELSFTIDRKHLELLDTDMKWVVEPGDFVLMAGASSEDIRLNGTLTVEDYQTRAKAI
                     EAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAIAFTRDN
                     NLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRVSIAEVK
                     F"
     CDS             10525..10674
                     /locus_tag="ctg24_13"
                     /transl_table=11
                     /translation="MAELLLVRKNFLFNLGMSKPNLGLDISRLGMEKPKFGIDCFLNSF
                     RFFS"
     CDS             complement(11386..11523)
                     /locus_tag="ctg24_14"
                     /transl_table=11
                     /translation="MNIKGRGSRRKEKAPELLEFKDLQTSFYYIRGAGGNRTLVQTRKS
                     "
     CDS             11640..12125
                     /locus_tag="ctg24_15"
                     /transl_table=11
                     /translation="MKIHEGKCTEKILKERERIGSRLAILRKKRNMTQEELANLCGVNR
                     VNIAKIEKGAYNVSIDILSKVTSALGFVIDIKVDSSVCPTHFSQRKPVKLVIGKDYYVS
                     FGNNEAHRCKLVDIPEMYQGQRIKIETPTPRGSITHILFADEIGTTPDEAVMNQVTM"
     CDS             complement(12325..13122)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 56; E-value: 7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_16"
                     /transl_table=11
                     /translation="MQKRHTDRESYFDEQSQTSKNYYIPYIKEVIGHIPDKVLEVGCGE
                     GGNLLPFAKAGCRVMGVDIDAMRIEQARTFFTQRHQQGQFISTDIFQLEDKATNFPLIL
                     LHDVIEHIRDKERFLSGLQKHLSADGAVFVGFPAWQMPFGGHQQIAHSHIVSHFPFLHL
                     LPRTLYRWILRLCGEQERVITELLDIKSTGCTIELFNRIARQANYQIIDRRLYLINPHY
                     KIKFGLSPRRLNGVIAAIPYIRNFFCTSCFYILKKGTKTVNHY"
     CDS             complement(13204..14634)
                     /locus_tag="ctg24_17"
                     /transl_table=11
                     /translation="MKKIMRNLALQYLNHANANPTIPLTDIPEEEEPAENPFCPDFISY
                     DKMLDIVESLPEGYCKVFKLAVLEGLSHKEIGDLLGIAPHSSSSQLFRAKILLKKMLAG
                     YRVFIVLTVLLLFPTLYDYLYREKKSIRENRLSKVSSRQAGSTQQTKKTDTPRTDEQCY
                     TKENLNKSERIIPPVPVSTEWPLAIPTMKDSIHKYPIPSPFTRQTITNRQMAFASSPSP
                     MPPTRKKKSGKWKLMLAGSLGPQLAQNLYKLIATPHTDGISSDFPQQVSTWEEYYSYLH
                     TRYQQGTLGKDSIGLMQIAQNNSGRIVENQQHHAPIVVGLSLSKKLNERWSLETGLQYT
                     LLRSEFTTGEAFRIQDNQKLHYIGIPLRLSYRFWHYKRFSGYATTGMQVDIPIKGTLQS
                     FHVTDSIPHKLGSHPVSAPWQWSVNTSIGIQYHLTPQAGIYLEPTVNYYIPDGSQLRTI
                     RKEHPFTFTLPVGLRISW"
ORIGIN
        1 ggcttatgac atcgcaggca agggactggc gagcgaggac tcgttccgtc aggcagttta
       61 tgttgccatt gatgtgttcc gtaatcgtca acgggagaaa gtagcccatg caaatccgtt
      121 gcggaaacag tattacgaga aacgggatga tagtgacaaa ctaaagctgg atacagtaga
      181 cgaagattaa taggaagtaa tgacaaaaac ggagatacaa caagtgaagc agcgtttcgg
      241 tattatcgga aataccgagg cattgttgcg cgccatagat gttgccattc aggtagctcc
      301 taccgatttg tctgtgctga ttaccggaga aagtggagtc ggaaaagaaa gttttccgca
      361 gattattcat caatatagcc ggaggaagca cggacagtat attgctgtca actgtggtgc
      421 tattccggag ggcacgattg attccgaact gttcgggcat gagaagggtg cgtttaccgg
      481 tgcgattggc gaacggaaag ggtactttgg cgaagccgac ggtggtacta ttttccttga
      541 tgaagtaggg gagttgccga tgtctaccca ggcacgtttg ctccgtgtac tggagagtgg
      601 cgagtttatg aaagtaggtt cgtccaaagt acaaaaaacg gatgtgcgtg tggtggcggc
      661 taccaatgtc aatctgacac aagcgattgc agaaggacgt ttccgtgaag atttatatta
      721 ccggttgaat acggtgccta tccaaatacc gcctttgcgt gaacgtggtg acgatgtact
      781 tttgttgttc cgtaagtttt ccgcagactt tgcagagaaa taccggatgc ctgctattca
      841 gttgacggag gatgcgaaga aagagttgtt ggcttacccg tggcccggaa acgtgcgtca
      901 gttgaagaac atcaccgagc aaatatctat cattgaaacc aacagggaga tttctgctgc
      961 tatcttgcag aattatcttc ccgcacaaaa tacgcaacgt cttcccgcgc tgatgggaac
     1021 gcgtgagagt aaaggctttg agagcgaacg ggagattctt tattctgttc tgtttgatat
     1081 gcgccaggaa gtggcggagc tgaagaagat ggtgcacaac ctgatggcgg aacgtgccgg
     1141 acaggtgggg caggtaggac aagtgggaac ggtggttact actccggtag tgacgacaca
     1201 ccagccttcg gtacctgcga tcattcatac catgcagcct gcggtttgca aggatgacga
     1261 tgacatacaa gacacggaag aatatgtaga agaatctcct ttgtcactgg acgaagtgga
     1321 gaaagaaatg atacgcaagg cacttgagag gcatcatgga aagcggaaga gtgcggccaa
     1381 ggacttgaat atttccgagc gtacacttta tagaaaaata aaagaatatg aattggatta
     1441 agaaaataat acgccctttg ctactgttcg gcttgccgtt ggtagtcatt gcgtgcactg
     1501 tttcctataa gtttaacgga tcgtctatca attatgataa ggtaaagacc atttcgatag
     1561 ccgacttccc gatcaagtcg gagtatgtat atgctccgtt ggcaaccaaa ttcaatgagg
     1621 acctgaaaga tatcttcatt cggcagaccc gtctgcaact gctcaagccg aatcagaatg
     1681 ccgacttgca gattgacgga gaaatcacag ggtacaatca gtacaaccag gcagtatctg
     1741 ccgacggtta ttcttcggag acgaagttga ctattaccgt caatgtacgt tttgtcaaca
     1801 acaccaatca tgccgaagac tttgaacaac agttttctgc gttccgtacc tacgactcta
     1861 gccagttgtt gactgccgta caggacggat tgattgctga aatgtctaaa gagatcaccg
     1921 accaaatttt taatgcaact gtagcaaact ggtaatataa atgacttctg ttaactttca
     1981 acaatggatt cagcatcccg agacgctgaa tagggatact ttgtacgaac tgcgcaatct
     2041 tcttgcgagg tatccgtatt ttcagtcact tcgtctgctg tatctgaaga atctgtatat
     2101 tctccatgat attagttttg gtggagaact gcggaaagca gttctttaca ttgcagacag
     2161 acggcagttg ttccggttga ttgaaggtga ccgctatgat gtgcaggcac ggaaaaaggg
     2221 agtacctctc acggaggtgc tgaaagacga accgtctgta gaccgcacat tagcattgat
     2281 cgacgctttc ttgtccacag tacccgaaga ggtgactgcc cgcaccagct tcgactattc
     2341 gatggattac acctctttca ttttggagga gactccggcc acggaacagc cggctgaaga
     2401 aacgcccaaa ctcaaaggct tcgactttat agaaaagagc gagagcgact ctcccctctg
     2461 catgaaacct ttaagagaag aaatgccatc ttcgccaacc tcttcggacg aacttaccga
     2521 agaagaaacg atgaaggaag aagaggaaga tgacagctgt tttacggaaa ctttggcaaa
     2581 aatctatgtt aaacagcaac gatattcaaa agctcttgaa ataattaaaa aattaagctt
     2641 gaaatatcca aaaaaaaatg cttactttgc agaccaaatc agatttttgg agaaattgat
     2701 tattaacgct aaatcaaaat aacaaaatgt atttattatt agttatctta atgctgattg
     2761 catctgtgct gatgtgcttc attgtattga ttcaaaattc taaaggaggt ggtctggcat
     2821 caggcttttc atcatccaac caaattatgg gtgtgcgcaa gactacggac tttttggaaa
     2881 aagaaacctg gactctggca gctgtcatgg tagtcttcag tattgtttct gcttacacta
     2941 ttccttcttc cacaggcaag ggcggtgatg tgattctgga acaggcgcaa caagaagaaa
     3001 aaactaatcc ttataacatg cccgtaggta cagaagctcc gcaatcggag gcccctgcag
     3061 ctacaactcc ggctgaaact cctgctcctg cagcagaagc ccctgcagca gaataagata
     3121 aggatattgc ggatgactcc cgcttggaaa aataagagaa aggttgatac tgaaaaggtg
     3181 tcagcctttt ttcgttttga tgaagtattt atttaccttt gtcagcaatt tatgcaatct
     3241 gattaataaa ttgaaatcca aatagtacaa tgacagaaca actcaaactt aaattgaatg
     3301 attccaaggc tacccgttgg ggggcattgg tgattgttgc cttcacgatg atggcagctt
     3361 attatgtaaa cgacgtggta gcaccgttga agacaatgtt ggaaacggac ttggcttggt
     3421 cgagtaccga tttcggattc tttaccggtg gttatagttt tctgaatgtt tttttcctga
     3481 tgttgatttg gggaggatta atcctcgacc gctttggtat ccgtttcacc ggaaagctgg
     3541 caactatcct gatggtaggt ggtacagcac ttgaatacta tgcaatgacg ggacttgccg
     3601 gtgccgacgc gactttattc ggaatcaatg aaatatttgg ctataaaacg ggtgtgtttg
     3661 ttgcttttgc cggttattcc atttttggag taggagcgga ggtcgccggt attacagttt
     3721 ccaaaatcat agccaagtgg tttaagggga aagagcttgc cacggctatg ggggtacaag
     3781 tcgctttagc acgtatcggt tcgcaagccg gttatgccgt agccattcct ttggcccgcg
     3841 ctttcggtat ttccacaccg gtgttgttgg gtttggttct gttgttgggc ggtatgattg
     3901 ctttcttcat ctttgcagtg atggacaaga agctggacaa acagatggaa gctgctgcca
     3961 ttgctgccgg tacggaagat gaggaagaga agttctcttt taaggatgtg aagaatattc
     4021 tggtcaatcc cggtttctgg ctgatagcat tgctgtgtgt attgttctac tcttttgtat
     4081 tcccattcca gaagtttgct tccgagttga tgattatcaa atacggtatc aatgagaatg
     4141 tggccggtac atttgccgga cttccggcat tgggagcgct gattctgact ccggtctttg
     4201 gtggtttcat tgacaagcgg ggcaagtccg catctatcat gctgctgggc tcggccatgc
     4261 tgatatgtgt gcatttcatt tatgctattc ccgatataaa ctattggctg gtagctattg
     4321 tgctgatgat aattttgggt atcgctttct cgctggtacc ttctgccatg tggccggctg
     4381 tggccaagat attcccggta agccagttgg gtacggcata cgcattgatt ttctttatcc
     4441 agaatatcgg tctttggggt attcctacat tgatagggtg ggtgcttgat gcctattgta
     4501 tatccggcaa gaaaccagat ggaacgaata tgtatgacta tacggtgcct atgtgcattt
     4561 ttaccggtat tgcctgcttg tcccttatag tggctctact gctgaagaag gcagacaaga
     4621 agtatggtta taagctggaa gagcctaata ttcagaaata ataggaaaag cggataccgt
     4681 atgatggaaa tacccgaagg aaaagtaagt ctgttggacg ctgttccggt ccgctgtgga
     4741 catataacaa ccgaatggga aggtgagtgc gccgtactcg cctacccacg gtttaaatac
     4801 gaatggatgc gtcgtttttt attgccgaag gggatgtctc ctgacatcca tgtgaggctg
     4861 gaagaacacg gtacagctgt ctggaatctg atagatggac atcgtaccgt gcgcgaaatc
     4921 atctctctac ttgccaggca ctttggggag gaagagaatt atattccccg ggtcaccgcc
     4981 tacgtaatgc agttgcgtaa ggatggattt atccagttga caatccggaa ttagaattcc
     5041 tttattccct atccactttt atcaatcctc ccgttgccgt atcaaacagc actttgatgg
     5101 tagaattctt gttgaacagt accggtgcga ggtattctac ggtgccgaat tgggtaatgg
     5161 gaagttggtc gtcaaacaat ttcttattgt tatacatcaa tgtcacttgt gccttgcccg
     5221 gaaggttata ggctacaccg tccactttct ttttgccttc ctcggtggca gatacatcgg
     5281 gacttttgag gtcggtgacg ctaatataat acggttcacc ggcaaggtca ttattggcca
     5341 ccactcccag ctttcgggaa aaacggaaag ccacttcatc tttcatctct ttaggcgtca
     5401 gccggatggt gaatgtcttg ggttctttct ttattttgcc cgagaacatt tccgtcatag
     5461 ccgtttcctg ctggttcaga ttgtcaagca tcagcttgag ttgggcgccg tccttgggca
     5521 tattgtctgc ttcgccgcgc aggagggcat tcttgctttc gcggatgctg tatatttcct
     5581 tagccaccag ctcggccatc ttggcactgg agttggacat cagtatttct tccgtcagaa
     5641 aactgcgtgg gtcaatgctg ctttcggtgg ctttggcttc gggcgtcttg gcagcaggct
     5701 taccgctgaa cggaatgttg atggagcgga caattccgtc ttcggtaagc tccataaggg
     5761 gtgctacggt cttgtctttc atcttcacga aatagacgtt gtccttatcc ggtacaccgg
     5821 ctatgcgggt ttctatctta tccagtgtcc agaactcctc gggttcggca gacacgttgt
     5881 tgagacgcag atagcggtcg gcatatctgc aaaattctcc gggagtgtaa gtatgtttgg
     5941 tggcttgcaa tacgatttct atttctgttt tgggtaacat ataggtcact ccgtagtctt
     6001 tgccacgcat cacaccggtg gttacgtctg tttgcgccag ggcagtggta gacaagaaca
     6061 gagctgagag catcaatata ttcttcttca taatgtacat tcgtttagac tgatttagct
     6121 aagggacaaa gttaatgaag ttatctttgc taaatattgc tttataaatt attaacagag
     6181 ctgacgaact gtacgcaaac cggcatgtcg actacaatgt cctgatgagt atcttccaag
     6241 agtccggtaa cttcgtttcg tttgtatacc tgaatgacat tgctgtcgcg gcaggcggca
     6301 agcaagtatt taccgttggg cgtgatgttg aagttgcggg gatggatgcc ggtgggctga
     6361 taacctacct ttgccaaggt cccattttcg ggattcacgg caaagatggc gatgccgtct
     6421 tctttcagac ggttgctggc gtagaggtat ttcccatccg gactgaggtg gatgtctgca
     6481 cttccacggg cggctacggt gtcggctgtg atagtctgta tctgttccag gcagccgtcg
     6541 tcgtaactga aggcaatgac cttaccggac agttcggtga tgagataggc aaacttcccg
     6601 ttagggctga atgtcagatg gcgcgggccg gaatctgcct caatgccaac ggcttccaga
     6661 gaagcatgag gaatagggtc gtcggggtgc atcacaaagc gcaggatgcg gtcggcactg
     6721 aagtcggtgg cgaagatata ctttccgtcc ggtgaaaaga ccgtgcaatg gatgtgggga
     6781 gtggcttgcc gtatggcgtc gggaccggtg gcagagcctt gaaagagcgt gtctgcagga
     6841 gccaaagtgc cgtctttctg taaaggaaag acggacatgg ttccaccgct gtagttggca
     6901 gtcaacactt cccggccatt ggtggccacg tagcaggggt cggcgccgaa ggtgggaacg
     6961 gtgttcagca ggcgcagttc tcccgtttcc cggtcgaagg caagggagct gagggctgct
     7021 gtgctgtcgt tcatttcact gacggcatag acaaattcgc catcttccga ggggacgagg
     7081 taggagggat tgggcaatgc cgctgaactg agcggaacgg ctgttcccgt ctcctgatta
     7141 aagcggaagg tatagatacc cttgcttgag ccattcgtgt aagtacctat tagcatggcg
     7201 agttcgtcct ggtcaccgtt agtgcccttt ggagaagagc cacatgctgt caaacctaat
     7261 ccgagcatac agaaaagaag tgttttcatt aattgaatgt gttaatgtgc caatatgcta
     7321 atgtgctaat tggctgcgct gtatatgctg catggtcatt ggtacattag catattggca
     7381 cattagcaca ttaaaattta acttcggcaa tactgacgcg gtcatcgttc agcacgatgc
     7441 ggaggtcgct ggcggtagtg cctttgaacg gataggaaat cagtttgccg tattcgctga
     7501 cggtgcccga atatacggtg aggaactgtc cgccaccgcc cgagagctgg atttcgaagg
     7561 ttgccggcag gttgttgtca cgtgtaaagg caatggcaac tttatctacc ttggctccgt
     7621 tcttcaaggc aaaggtaata taatctccct tatttccttg ccatgcggta ttgatttttt
     7681 cgtcgagcac gttttcggca tcctctgggt tggtgctggc actcacacgc tttgctggtt
     7741 tttgggcttc aatggctttg gcacgggtct ggtagtcttc tacggtcagc gttccgttca
     7801 ggcggatgtc ttcggaagag gcgccggcca tgagcacgaa gtcgccgggt tccaccaccc
     7861 atttcatgtc ggtgtccaga agctccaggt gcttgcggtc gatggtgaag gacagctcct
     7921 gggcttcgcc cggttcgagg tggatgcgct ggaagcctgc aagattcttt tcgtaggtgg
     7981 tgatgctgct cagtacgtcg cggatataga gctgcactac ttcatctccg gcacgtttgc
     8041 cggtgttggt caccttcagg tggacggtgg cagactcgtt cggggtgatg actcggggag
     8101 tgatgtcgag gtcggagtac tcgaaggtgg tgtagcttaa gccgtaaccg aaggggtaca
     8161 gtgctccgtt gatgcgtgac atgttgcccg tgggccccag attcttaccg ccgtctatct
     8221 gtgaagaagg cttgcagggg aagttgaagg ggatttgccc tacggtcttg gggaaggtca
     8281 ctgtcagctt tccaccaggg ttgtagtcgc cgaagaggat gtcggccagg gccattccgc
     8341 ctttggagcc gggataccag gcttcgagga tggcggggac gaacttgtct gcccagttga
     8401 tggagagcgg gcgtccgttg atgagtatca gtacgacggg cttgcccgtg gcttgtatgg
     8461 cttgaagcag ttgcaactgc cggccgggca ggtcgaggct ggtgcgcgat ttgttttcgc
     8521 cgcaggtgcg ttgtccaccg cccaatacta cgacggcaac atcagcttgg cgggcatttt
     8581 ctacggcttt gtctatctcg gcttgctcgt cgtcggtcag aggatagtct atgatttcac
     8641 tttcgggcca gtgggcatct accaggtcgc agcctttggt gtagagcacc tctgccttgc
     8701 cttttgtctt ttcttgaatg ccttccagta cagtggtcac ctctacggca agggggccgt
     8761 aatgggtcag cgcgtagcct tcttcgttgg cattgggacc acagacggca atcttcttgg
     8821 tggagttgat gtctaagggc aacagctcac cggcattctt cagcagaacg atggactcgc
     8881 gggatgcctg caaggcgatg gcttcgttct cttctttttc cacttcacgg tcggcaccgg
     8941 caaggtctgt ctggtagggg gcatcgaaca gaccaatgag gaactttacc cggaggatgt
     9001 cgcgcacacg gtcgttaatg acttcttcgc tcagcccgcc ttccttcacc agttcgcgga
     9061 ggggaaggac gaaggagtcg ggcgagcgga aggtacagcg tacgttcagc ccggcttcca
     9121 cgctttggcg gacggcttct ttcatgtctt tggcggtgcc gtgcttggtg tagaggtatt
     9181 ctacggcgtc actgtcggat acgacgtagc cacggaatcc catttcgcca cgcaggcggg
     9241 tggtgagcca gtagtagctg ccctgcacgg ggatgccgtc gtaatcgttg tacgaactca
     9301 ttacgcccag catgccagct tcccggatga cgcgtttgaa ggggtagatg tgtatgtttt
     9361 ccacttcgcg cggcgacatt tgcgggtcca cgcgtgccat gccttcgcgg gcgcctttgt
     9421 tgttactgta agcggcaaag tgcttgccgg tggcggccac ttggtggttg tgctgcaagc
     9481 cgcgcaccat ttcgatgccc agttcggcta cgaggtaggg agattcgccg taaacttctt
     9541 cgtagcgtcc ccagcgctgg tcgcgtccta cgtcgaggat gggggcgtag acgttggtgt
     9601 agcccagcat gcgggcttcg cgtccggtga tgagtcctac ttggcgaatc agttcacggt
     9661 tccaggtatg tcccagtccc agttgggtgg ggaagttggt ggcgcggtag ctttccacgc
     9721 cgcgtatgcc ttcgttggta aagtctacgg ggatgccgag acgggtatct tccacaaaga
     9781 accgttgcac ctcgttcagt gcccaggcgt ggcgcgaggc gggccagacg taggcattgt
     9841 ccgagggagg cagcccccat tgctggaagc cgttcaggtg ttcgtcgatg gcgccgatac
     9901 cgtctttcca gagcagctct ttccattcgg gggtggggag gtcgtctttc agtacgcgtt
     9961 tgtagccgta gagggtgacc atttggcagg tcttttcgtc cagcgtcatc tgttgcagca
    10021 ggttttcgat gcgtgcttcg agcggggcgg aggggtcttc gtacacgtct ttcactccgt
    10081 ttttgttgaa gtctatccaa cctttgcggt acatttcact tttcaccggc ttgtaggttg
    10141 ccggtgtttt ggcaggcttt tgtgcgcaga gcagtgtgct tcctccaagc agcagggtta
    10201 gggcaataag gttcttcatg atatgttcta aaaatctctt ggttattatt gtttcttttg
    10261 ttgacaaaaa tacggctaat gtgtgaaata aagggataaa atagtccgaa gtatcggctt
    10321 ttattgtccg aagggtcttc ctcttactaa aaatatcctc caagacgcta ccggggaatt
    10381 caaatcatta ttagacgaaa catatcattc acttttaaaa agaaagaaca ctataataac
    10441 ctgaaaagta gatgcaatcg cggtgtatac aagtattacg gctacatctg ttaaacgagg
    10501 gtgtatttat ataataggaa tctgttggcg gaattgttgc ttgtacggaa gaactttctt
    10561 ttcaaccttg ggatgtctaa accaaacctt ggtttagaca tctcaaggct gggtatggaa
    10621 aaaccaaagt ttgggataga ttgcttcctt aattctttcc ggtttttcag ttaacttcag
    10681 agactttttc cgttaacttc ccatctcttt tgtgcaaata tccattacag aagatagata
    10741 ttccctcttg cagggggtaa ttccgtcaac ggatactggc tttggtagct gtttgaacat
    10801 tgatgacaat ggggtgcaca tattctatgt atggaagatt attgttttta tcacgaaaag
    10861 tcagtattag ctaatatttg taaatatatg gtgattgcta ataaaagaat atgtatcttt
    10921 gggccaaaga aagcggtaga ggatgaaaaa taaagtagca tttatccctt tttcaccctc
    10981 cctacttagc aatgagttac gcaatctttt aaatttcaga ccgttacaaa gtcatggggt
    11041 tgactggatt tgacagcggg cagaaatggt aagtaagcat gcagtgcgtc gttgatttgc
    11101 actttaatct cagtcctcaa aattttatct ggcgaaactc gttacgctct cgctgcttaa
    11161 tcgaagtata gtagattgaa gcttaatccc ggcaccaggt gctgggacgt gacatcactc
    11221 ggaagctgtt gctccgaagc attccgataa agtggtgcag tcaaatcggg gatagttcgt
    11281 gtcagcctcg tggcgcgggt gaaaatttag aggataaggc aacggttgat ggctttggtt
    11341 ctgccgctgc acgaaaattt aggcaaagat aagcatgtag aaagcttatg atttcctcgt
    11401 ttggacgagg gttcgattcc ctccagctcc acggatatag taaaaagaag tttgtaagtc
    11461 cttgaattcc agtaattcag gggctttctc ttttcttcta ctccccctac cttttatatt
    11521 catttagaaa acggttgtag taaatgtgct acaatttaaa attaatatct acttttgtct
    11581 gttcaaaaac caataactat tagaagtggg ggcaacactt taaattctgc aacagattta
    11641 tgaaaattca cgaaggaaaa tgtacagaga agattttgaa agaacgtgaa cggattggta
    11701 gtcggttagc cattcttcgc aagaagagaa atatgaccca agaggaattg gctaatcttt
    11761 gtggtgttaa tcgtgttaat atagccaaga tagagaaagg ggcttataat gtgagcattg
    11821 atatactatc taaggtaaca tccgctcttg gttttgtgat agatataaaa gtggatagct
    11881 ctgtttgtcc gactcatttc tctcaacgta aacctgtaaa gctggtaata gggaaagact
    11941 attatgtcag ttttggcaat aacgaagccc atagatgtaa gctggttgat attccggaga
    12001 tgtaccaagg tcaaagaatt aaaatcgaaa ctccgacccc gagagggtct atcacccaca
    12061 tattatttgc cgatgaaata ggaacgacac ctgacgaggc tgtaatgaac caagtaacga
    12121 tgtaaaaaca ttaaaaggga ggaagtgcaa gttcctcttt tattgaaatc cccttcgcta
    12181 caaccatctg cagtgagggt gattttttag tttatgaggg tttctacacc ccctctttca
    12241 tcagagctat tcaaaaattt aatggtttct tctgaatata taatcttaaa ttgatggttc
    12301 ggaatcaatt ctaaagctgg gaaatcagta gtgattaaca gttttagtcc ctttctttaa
    12361 tatgtaaaag caacttgtac aaaagaagtt tcttatgtac gggatagcag caataactcc
    12421 gttgagcctt cgtggggaca agccgaattt gattttataa tgtgggttta taaggtacag
    12481 tctccggtca atgatttgat agttggcttg ccgggcgatg cgattgaaca gttcgatggt
    12541 gcatccggtg ctctttatat ccagtagctc cgtgattacg cgttcctgct caccgcatag
    12601 tcttaatatc catctgtata aagtgcgggg aaggaggtgg agaaaaggga aatgtgaaac
    12661 aatgtggctg tgtgctatct gctggtggcc tccgaatggc atttgccagg cgggaaatcc
    12721 tacaaataca gctccgtcgg cagacaaatg tttttgtagg ccggagagga accgttcttt
    12781 gtctctgata tgctctatca catcgtgtag aagaatcagg ggaaaattcg tagccttgtc
    12841 ctcaagctgg aaaatgtcgg tggaaatgaa ctgtccctgc tgatgccttt gggtgaagaa
    12901 ggtcctggct tgctctattc gcatggcatc aatgtctacg cccatcaccc ggcaaccggc
    12961 tttggcaaag ggaagcagat tgcctccctc tccacagccc acttccagca ctttatcggg
    13021 gatgtgtccg atgacttcct ttatgtaggg gatataatag ttcttgctgg tctgtgactg
    13081 ttcatcaaag tagctttccc ggtcggtatg tcgtttctgc atgttctttg ttccttcttg
    13141 agtttgatta tccatataaa tagataatca gtcgggtaaa agactgcgtg gcgcatcgtt
    13201 tttttaccag gaaatgcgga ggcctaccgg gagggtgaat gtgaacgggt gttcctttcg
    13261 gatggtgcgc agttggctgc cgtcggggat gtaatagttt acagtcggct ccagatagat
    13321 gcctgcctgg ggtgtgaggt gatattgtat gcctatactt gtgttgaccg accactgcca
    13381 gggagcactt accggatgac tgccgagctt gtgtggaata ctgtccgtga catggaagct
    13441 ttggagtgtc ccttttatgg ggatatccac ctgcatgcct gtcgtggcat aaccggagaa
    13501 acgtttgtaa tgccagaaac ggtaggaaag ccggagaggg atgccgatat aatgcagctt
    13561 ctggttgtct tgaatgcgga atgcttcgcc ggtagtgaac tccgacctga gaagcgtata
    13621 ttgcaatccg gtttccagac tccaacgctc attcaatttc ttgctgagag agagtcccac
    13681 gacgatgggg gcatgatgtt gctggttctc aacaatcctg ccgctgttat tctgggcaat
    13741 ctgcatgagt ccgatggaat cttttcccag agtaccctgc tgatagcggg tgtgcagata
    13801 agaataatac tcttcccacg tactgacttg ttgagggaag tcacttgaaa tgccgtcggt
    13861 atgtggagtg gcaatcagct tatataggtt ctgtgccagt tgcggtccga gtgaacctgc
    13921 cagcatcaac ttccatttcc cggatttctt cttgcgggtt ggcggcatcg gggaagggga
    13981 ggaggcgaaa gccatctgtc ggttggtgat ggtctgtctg gtgaatggag aaggtatggg
    14041 atatttgtgg atactatctt tcattgtggg tatggcaagg ggccattctg tggaaactgg
    14101 aacgggaggg atgattcgtt cacttttgtt cagattttct ttggtatagc attgttcgtc
    14161 ggttcgggga gtatcggttt tctttgtttg ttgcgtactc ccggcttgcc tggaagaaac
    14221 tttggacaaa cggttttccc tgatactctt tttctctctg tacagatagt catacagcgt
    14281 tggaaagaga agcaatactg tcaaaacaat gaatacacgg tatcctgcca gcatcttttt
    14341 aagtaaaatt ttcgcccgga acaattggga ggaagaggag tgtggcgcta tacccagtaa
    14401 atctccgatt tctttgtggg acaatccttc cagtactgcc agtttaaata ccttgcagta
    14461 gccctccgga aggctctcca ctatatccag catcttatcg tacgaaatga aatccggaca
    14521 aaaaggattt tcagcaggct cttcctcttc cggaatatct gtcaatggga tggtggggtt
    14581 ggcattggca tggttgaggt attgcagtgc caggtttctc ataatctttt tcatccagta
    14641 ttccagtttc tccgggttgc gcagcgaatg aatggaagtg aatatgatga caaaaccgtc
    14701 gtgaagaaga tcttgggcta tcgttgggtc gggaatatag cgtaggcata ctttcagcat
    14761 tttctctgaa tagttttcgt agagcaggct caaggcctgc ccgtttccct tctggcataa
    14821 agtgacaaga gcttttgtat ccatgtgttt gtctcaatgt tatttcttaa ggatagagaa
    14881 gaacatgaat gactgcatgg atttttattt tttaactaag cctcccggtt gacttctgct
    14941 gcacagtccg gacaaatgcc tttcagtaca tagttgatgc tgttcagtgt aaatccttga
    15001 ggcagcttca ccaccggagt gggaatgttg gtga
//
