LOCUS       c00044_gnlPro..        17569 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMJBEFCL_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:34:00
            Original ID  :: gnl|Prokka|OMJBEFCL_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 10799
            Orig. end    :: 28368
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17569
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[20799:24270]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13471
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17569
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17569
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1733..2713
                     /locus_tag="ctg44_13"
                     /transl_table=11
                     /translation="MDILFLVGGLLLILLGANGLTDGAASVAKRFHIPSIVIGLTIVAF
                     GTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCTALFAPIAITRNTLKREIP
                     LCILSSFALLICANDVLLDSSGENILSITDGLLLLCFFTIFLSYTFAIAKRDGSMKEPE
                     KEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGASGIARGLGVSESIIGLTLV
                     AGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLGCSASITPLRLTGITNFDL
                     WVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVLIYNL"
     CDS             2864..4000
                     /locus_tag="ctg44_14"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             4136..6052
                     /locus_tag="ctg44_15"
                     /transl_table=11
                     /translation="MTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVRSGMYIG
                     RLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRGIPQGKL
                     VEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRTAIFEKGTL
                     LSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIYNGQRIV
                     SRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTTQGGTHQ
                     TALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNNMWPAAP
                     QEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGVTKLARE
                     RAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNTQAVFSL
                     RGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGMHIRLLI
                     ITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNPEITRFK
                     GLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINNLVIEED
                     LAS"
     CDS             6049..6507
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_16"
                     /sec_met_domain="CTP_transf_like (E-value: 1.2e-18,
                     bitscore: 58.6, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             6622..8145
                     /locus_tag="ctg44_17"
                     /transl_table=11
                     /translation="MAEFAITNLYVDKVDEDKLVEEAIIKMLAQLDPHSTYNNAEEVKK
                     MNEPLQGNFEGIGVQFQMIEDTLLVIQPVSNGPSEKVGILAGDRIVAVNDSAIAGVKMS
                     TEDIMSRLRGPKDSEVKLTIVRRGVDDQLYFTVKRDKIPILSLDASYMIQPKTGYIRIN
                     RFGATTAEEFAEALKSLQKKGMKDLILDLQGNGGGYLNAAIDLANEFLKQKELIVYTEG
                     RAARRSDFFAKGTGNFKNGRLIILVDEYSASASEIVTGAIQDWDRGVVVGRRTFGKGLV
                     QRPIDLPDGSMIRLTIARYYTPSGRCIQKPYDSTANLDGRLTGENSQDKYNQELIDRFN
                     HGEMIHADSIHFADSLKAQTKRMGRTVYGGGGIMPDFFVPIDTTQYTDYHRNLVAKGVV
                     IKATTGYIEKHRKELQNKYKRFEAFNEKFEIDDNFLAEIRTLADKEKIKFDEKQYNQSL
                     PLIKTQLKALIARDLWDMNEYFQVMNSTNQSVQQALKVLNEGIYSTIIQ"
     CDS             8330..8692
                     /locus_tag="ctg44_18"
                     /transl_table=11
                     /translation="MHSLVHTGNSHGTSPQGRRSYHIPFRILYTERGGKGKSRRRMSRR
                     KRRAAFMAICMHSVGIFIIRTLTVHQIFHSISHNKSPRYTCTYVDRIFQQTLIMFYPSG
                     NRHRHRNTDSNIGLRT"
     CDS             9068..9838
                     /locus_tag="ctg44_19"
                     /transl_table=11
                     /translation="MIFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEY
                     IVYWFTELPLICEERYKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKY
                     IEMKCQELVYILTCYYPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYT
                     TTTFRRLFKNMYGVPVYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCK
                     DSFGDTPRALRKRSANGEKISIICKEQGKDQEDE"
     CDS             10001..10699
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_20"
                     /sec_met_domain="SucD_FumR (E-value: 2e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(10811..11875)
                     /locus_tag="ctg44_21"
                     /transl_table=11
                     /translation="LCNDIFTQTVDSFGEVKEYGKTGVVHAEALVAAFFGSAAGNVTRN
                     EVTECRITAFQVVVAVFLGNIFSLQCTFLQFLGIFQLLRNPDTTIVTQRFGHQSQLRLL
                     VTVNRDTSGVNLYVSRVGKPGTFTVASHCCRAVTCHCIGRKEVGIAVTTGSDYHSVGGK
                     TFQFTGNEVLCNDTAGTSVNEDNVFHFVAGIQFHSAYVHLAAQCRVCTQQQLLSGLTLG
                     IESTGYLSTTERTVVQCTAVFAGERNTLCNALVDNIVGYFSQTVNVGFAGTVVATLYCI
                     VEQTVYRVTVVLVILSSIDATLCSDGVCTARRVLDAEVEYSETHFAQRGGSTGTGKSGS
                     YYDDVQTTFVGRVY"
     CDS             11939..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_22"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.6e-13, bitscore:
                     38.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3e-38, bitscore:
                     121.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGA
                     SALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNIKGKK
                     SVDSIHKELGHIMWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDK
                     AIRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSD
                     EKEPVLLKEPLVYEAIKVQTRNYKS"
     CDS             12716..13471
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_23"
                     /sec_met_domain="Fer4_7 (E-value: 2.5e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 8e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.4e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(13610..14224)
                     /locus_tag="ctg44_24"
                     /transl_table=11
                     /translation="MTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQ
                     LFLESSKAYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVL
                     QNHAKVKTVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASIS
                     EICYKYGFESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             14276..14518
                     /locus_tag="ctg44_25"
                     /transl_table=11
                     /translation="MQHSSRILLTVDKHFSFQQENYNIFLTLSRRQMESSEVGSIYYCI
                     VHSLGTLSALFFTSASRRVGHRQVDLFVCCSDKNR"
     CDS             14574..14951
                     /locus_tag="ctg44_26"
                     /transl_table=11
                     /translation="MNKIEVIQFFIADSAVLFFHVRIISRTPWTNFRYKGYFCRLIGQR
                     QRITYLFAFTPGLCIIQVNGGSYSIKKNVFLIDVIDNIDFGIRIQRLGHQHPGCIHFHT
                     RCIHFQCTAGNRMRISGCSFL"
     CDS             15153..15578
                     /locus_tag="ctg44_27"
                     /transl_table=11
                     /translation="LGSYICYRISNGRIYSTSSRLIVRQGSGTRIPVSKELQVIRHWPI
                     ICSPSQTPVGSTIGYFNICHEFLHRIKSRNGGHCCRSRIISIHSEPYLLQFRQISHCGS
                     RSVTHYCSQFNLRLLSGILYLLTFRATHYCCCSQSQK"
     CDS             complement(15636..16619)
                     /locus_tag="ctg44_28"
                     /transl_table=11
                     /translation="MSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSGVQIKLDW
                     KGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNTESIQIRG
                     DESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLNWKPEAVVDH
                     YSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLLWGYFSSF
                     VLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPDVGVPGSE
                     IHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             complement(16616..17191)
                     /locus_tag="ctg44_29"
                     /transl_table=11
                     /translation="MMSGQVIGQNKSVESHSHTCKTVLALKNKLLYDLALAPNIEVELP
                     LGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHTRGRLSGHFLGAYAEGG
                     TYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIGYLDTEYRKYTSYGNDL
                     VWVSCGKYHFIGPTKAKVSLVWFLTSGR"
ORIGIN
        1 catctatcac tccaggagta ttcaatgcag cctctatcaa cagctgatgt gtcttccgcc
       61 acggaacatc gtagccaata ctgacctccg aatggataat caatccatac tcacgggcag
      121 actggctgta attgaccgta tgggaagaca tgatgaaaga gttcggaatg gtcaccacct
      181 cattcttcgg agtacggatg cgggtgacga gcggtgtttt ctcaatgatg ttgcccgtag
      241 tatcgttcag cttgatgcgg tcacccagct tgaaaggccg catgtaggtt atgaccagtc
      301 ctgcaatgat attgccgata accgtactgg aaccgagcga aacaatcaag ccgacaaaca
      361 cggagattcc ctggaagact cccgacttgg aacccggcag ataagggtaa atcatggcaa
      421 tcataaacgc ataaagcaag aagcgcacaa tatgataggt aggaatggcc caatccggat
      481 agaagccgtt tatcttcagc cgttcagcct gcacctcatt ggcaagatag cgcaccagtc
      541 tgaccaggta cttcaccgca tagcatatca caaagattgt gaacagattg ggtatatagt
      601 cggttattcc attcagaata acctttatag gattccagat gtaggagaat aatgtataag
      661 ccaagctctt ggtctgaggg aaaatggaga ataataacgg aaccgtcagc agcaactgca
      721 acagcatgac tacataacgc accaggttgg caacaaacac cagcaggttg acctgcttct
      781 gcgtatccag caattcataa tcctgaatag agatcggttt cagcttggta tccttcagct
      841 tctgaatgcg tagtttgagt tttctgaaca gccagttggt aaacttgaac aagaagaact
      901 gtcccacaag caccaggata aagtacaaga tacgcttacc caactgccac aagctatgct
      961 ccttctgcat ggctttcagt ttgtccacca cgacatgcct cttgctggcg gccagctggt
     1021 cgcgggtaca gttttcccac aaagcatcct gatcggtaaa ggaaatgatg accttttcgc
     1081 catacatcaa gtctgtaaca atatccgtac tctctaaata aacagagtcc ggacgcagat
     1141 tgaaacgcgt gcccaatgct tcgatgacgt tgcttacatc tttggctcgc tgttggggcg
     1201 tatgccctcc acgcttggca tacagataga acaaagtgtc cttctccacc accaccggaa
     1261 tacccggtgt caccgtccgc aacgaatcaa tgcgttgttt ctgcaatgcc agcttcaccg
     1321 aatcggccgc atagcccgcc aacttcatct gctccatttc catccgcagg ttcgcctcat
     1381 tcagccgggc tgtttccaac tcctgccgga caagcgacaa ctgaatcgaa tcggagtcag
     1441 tccttgccac tgtgacactc cccacactat cctcacctaa aacactgagc actttatcta
     1501 ccaactgagc tgacactccg tccgccagca tcaacagcca acaaagacag aaagcacgga
     1561 taaccttcat atataaactt cttgatttga ttctttgcaa atatacccaa taaatgcttc
     1621 aaacatacgg aatgttttta acttcctact ctaatcgaca taactttttc atgcaaacat
     1681 gaaagttctg tatccggttt gcactatctt tgtactcaaa attgacatac ctatggatat
     1741 attgtttctt gtcggaggac tgctcctcat tcttctgggt gccaatggct tgacagacgg
     1801 tgccgcatcc gttgccaaac gtttccatat accgtccatc gtcatcgggc ttaccattgt
     1861 tgccttcggc acttccgcac cggaactcac cgtcagcata tcctctgctc tcaaaggcag
     1921 tgcagacatt gccattggca atgtggtggg aagcaatacg ttcaataccc tgatgattgt
     1981 gggttgtacg gccctttttg ccccgatagc cattacccgt aacacactga aacgcgaaat
     2041 ccccctttgc atcctttcat ccttcgccct gctgatttgt gccaacgacg tcttactgga
     2101 cagcagtggg gagaacatac tcagcatcac cgacggccta ttgctgctat gcttctttac
     2161 cattttcctg agttatactt ttgccattgc aaaaagggat ggaagtatga aggaaccgga
     2221 aaaggagcac ttacaggaag aagacgaaat caggctgtta cccgcgtgga agtccgccct
     2281 atacattctc ggcggacttg ccggcctcat catcggaggt aatttctttg tagacggtgc
     2341 cagcggcata gcccgcggat tgggtgtcag cgaatccatc atcgggctga cgctcgtagc
     2401 aggcggcact tcactgcccg aactcgccac ctccatcgta gccgccttga agaaaaaccc
     2461 cgaaatagcc atcggaaacg tcatcggaag taatctcttc aatatattct tcgtactggg
     2521 ttgttcggcc tccatcactc cactgcgtct gacgggcatc accaatttcg atttgtgggt
     2581 actcgtaggg tccagcatcc tgctttggct gttcggtatc tttttcggga aacgcatcat
     2641 cacccgggtg gaaggaagca ttctgattct ctgctacatt gcctacacag cggtactaat
     2701 atacaacctc taacagcaaa tttacaaaca ccctatgcgg tattttaaag attatcacgt
     2761 atttttaaat aaggcaagct gtacctcggc ataaaaaata agcaagctta ttttgttctg
     2821 ctctcagttt gcattacctt tgtggtctca atattgaaca actatggcaa ttacaatcaa
     2881 gaaagtaacc acaagacggg aactggagcg ctttatccgt ttcaactacc tgctatacaa
     2941 aaacaaccct tattccgtcc ccgacctttt cgatgacatg ctcaacacct tcaacaagaa
     3001 gaaaaacgct gcattcgaat tttgtgaagc cgactatttc ctggcttatc gggaaggtaa
     3061 aatcgtagga cgtgtagctg ccatcatcaa ccacaaggca aaccaaacct ggaacaaaaa
     3121 ggaagtccgc ttcggctgga tagacttcat cgatgatgcg gaagtctccg atgccctgat
     3181 tcgcaccgtg gaagaatggg gaaaagaacg gggaatgaca catatacaag gcccgctggg
     3241 attcacagat ttcgatgccg aaggtatgct catcgaagga ttcgaccagc tcagcaccat
     3301 ggccaccatt tataactatc cctactatcc gcaacatctg gaacgcatgg gctttgagaa
     3361 ggatgccgat tgggtggagt acaaaatcta cattcccgac gccatacccg acaagcacaa
     3421 gcgcatctcc gacctcatcc agcgcaagta taacctcaag gtaaagaaat acacatctgc
     3481 caagaagatt gcccaagact acggtcaggc catcttcgaa ctgatgaacg aagcctatca
     3541 gccactctat ggctattctg cactgagcca acggcagatt gaccaatacg tcaagatgta
     3601 cctgcccatc ctcgacctac gcatggtgac attgattacc gatgccgatg accagctgct
     3661 tgccgtaggc atttccatgc cgtcactcgc cgaagcgttg caaaaagccc acgggcgcct
     3721 gcttcctatg ggttggtatc acctggccaa gaccatcttc ttgaagaaat atcccaagat
     3781 gctcgatttg ctgctggttg ccgtgaaacc ggagtatcag aacaaggggg taaatgcatt
     3841 gttgttctcc gaccttatcc ccgtctatca gcaacttggt ttcgagtatg ccgagagtaa
     3901 tccggagctg gagctgaacg gcaaggtgca agcgcagtgg gagtacttca agacggaaca
     3961 gcataaacgg agaagatgct ttgtgaaagg aataaaataa gttctaaatc cagaatataa
     4021 gcttgtcaga agtccataaa agacattatt tttttgcgaa cccccgaatt tctcattacc
     4081 tttgtcgcaa tgcgcaatat gaaggaataa cgtacttatg gaagataaca acaatatgac
     4141 cctgccgctg gaagaagcag acaacaatat cacagagagc cccgtttcca gcgtggaata
     4201 taccgacgac aacatccgcc acctggacga catggagcat atccgtgtcc gttccggtat
     4261 gtacataggc cgtctgggcg acggctcaca gaacgatgac ggcatctatg tgttgctgaa
     4321 agaagtgatg gacaacagca tcgacgagtt caagatgggt gccggaaagc gtatagaagt
     4381 gactatagaa gacagtctgc gtgtcagcgt acgcgactat ggacgaggca ttccgcaagg
     4441 caaactggta gaggcggtca gcaaactgaa taccgggggt aaatatgact cgaaggcttt
     4501 caagaaaagt gtcggactga acggcgtggg catcaaggcg gtcaatgcgc tgagtagccg
     4561 tttcgaggta cgcagttacc gcgacggcaa agtacgtacc gccatcttcg agaaaggaac
     4621 gctgttgagt gatgtgaccg aagactcgac agaagaaagc ggaacctata tcttcttcga
     4681 accggacgcc acactcttcc tgaactattc cttccagaac cagttcgtag aaaccctgct
     4741 gcgcaactac acctacctga atacgggcct caccttcatt tacaacggcc agcgcatcgt
     4801 ttcccgccac gggctggagg acttgctgaa agacaacatg accagcgaag gcctttacga
     4861 catcatccac ctgaaaggag aggacatcga gattgccttc acacacacca accaatacgg
     4921 cgaagagtac tactcctttg tcaacgggca acacaccacc caaggcggca cacaccagac
     4981 tgccttgaag gaacacattg cccgtaccat caaggagttc tacaacaaga accaggaata
     5041 tgccgacatc cgcaacggac tggtagccgc cattgccatc gacgtggagg aacccatgtt
     5101 cgagagccag accaaaacga aactgggcag caacaacatg tggcctgccg cgccgcagga
     5161 acacaagccc gccggcccca cggtgaacaa atacgtagga gacttcatca agacggaagt
     5221 ggacaactac ctccacaaga acccgcttgt ggccgaagtg atgctgcaaa agatacaaga
     5281 ctccgagaaa gagcgcaaag ccattgccgg cgtcaccaag ctggcacgcg aacgcgccaa
     5341 gaaagccaat ctgcacaacc gcaagctgcg cgactgccgc taccacttga gtgacggtaa
     5401 aggcaaagac caggaaaccg aatcctgcat cttcattacc gagggagact ccgccagcgg
     5461 ttccatcacc aagagccgcg acgtgaatac ccaagcagta ttcagcctgc gtggtaaacc
     5521 gctaaattcc tacggactca ccaagaaagt agtttatgaa aacgaagaat tcaacttgct
     5581 tcaagcagcc ttgaatatag aagacggcat agagacactg cgctacaaca aagtcatcgt
     5641 agctaccgat gccgatgtgg acggcatgca catccgcctg ctcatcatca ccttcttcct
     5701 gcagttcttc cccgacctga taaagaaagg gcatgtatat atcctgcaaa cccctctctt
     5761 ccgcgtgcgc aacaaaaaga agacaagtta ttgctataca gaggaggaac gtgtgaaagc
     5821 cattgaagaa ctgggtccca accccgaaat cacccgattc aaaggtctgg gagaaatctc
     5881 gcccgacgag ttcaagcatt ttatcggcaa ggatatgcgt ctggaacaag tgtccctgcg
     5941 caagacagac ctcgtaaaag agctgctgga attctacatg ggtaagaata ccatggaacg
     6001 acaaaacttt attatcaaca acttggttat agaagaagat ttggcatcat gagaagagct
     6061 atctttccgg gaacattcga cccgtttact atcggacact cttcggtagt gagccgtgca
     6121 ctgactttta tagacgaaat cgtcataggc atcggcatca atgaaaataa gaatacgtat
     6181 ttccccctgg aaaagcgcga acaaatgata cgagactact accggaacga gccgcgcatc
     6241 attgtgcagt cctatgactg cctgactatc gactttgccc ggcaggtaga tgccagtctg
     6301 ataatacgcg gcatacgcac cgtgaaggat ttcgaatacg aggaaaccat tgccgacatc
     6361 aaccgcaaac tgaccggcat agaaaccatc ctgctcttca ccgagccgga acttacctgc
     6421 gtcagttcca ccaccgtgcg cgaactgctg caatacggca aggacataag catgttcata
     6481 ccggagggaa tggagattag ggattaagga ttagggatta aaatggaaat gatgaaaaaa
     6541 ctatttacta ttataatatg tatatgcgcg gtgacggcgc aagcgcaaaa gccgaacaat
     6601 gaagccctgc gcaaactgca aatggcagag tttgccatca ccaaccttta tgtggacaag
     6661 gtggatgaag acaagctggt ggaagaagcc atcatcaaga tgctggcaca actcgacccg
     6721 cactccacct acaacaacgc cgaagaagtg aagaagatga acgagccgtt gcaaggcaat
     6781 ttcgagggca tcggcgtaca gtttcagatg atagaagata ccctgcttgt gatacaaccc
     6841 gtgagcaacg gaccttccga gaaggtgggc atccttgccg gcgaccgtat cgtagccgtc
     6901 aatgacagcg ccattgccgg agtaaaaatg agcacggaag atattatgag ccgcctgcgc
     6961 ggaccgaaag actcggaagt gaaactcacc atcgtgcgcc gtggcgtgga cgaccagctg
     7021 tacttcaccg tgaagcgtga caaaattccc atcctcagcc tggacgcatc ttacatgata
     7081 caacccaaaa ccggctatat ccgtatcaac cgcttcgggg caaccaccgc cgaagagttt
     7141 gcagaagccc tgaaaagcct gcaaaagaaa ggaatgaaag acctcatcct cgacctgcaa
     7201 ggaaatggag gagggtatct gaatgccgcc atcgaccttg ccaacgaatt tctgaagcaa
     7261 aaagaactca tcgtctacac cgaaggaagg gccgcacgcc gcagtgattt ctttgccaaa
     7321 ggtacgggca acttcaagaa cggccgtctc atcatattgg tggacgagta ctccgcttct
     7381 gccagtgaaa tcgtgaccgg agccatccag gactgggaca gaggcgtggt agtaggacgc
     7441 cgcaccttcg gcaagggatt agtacagcgt cctatcgacc tgccggacgg ttccatgatt
     7501 cgcctcacta tcgcccgcta ctatactcct tcgggccgtt gtatccagaa gccttacgac
     7561 agcaccgcca acctcgacgg ccgcctaacc ggcgagaaca gtcaggataa gtataaccag
     7621 gaactgatag accgcttcaa tcatggagaa atgattcatg cggacagtat ccattttgcc
     7681 gactccctga aagcacagac caagcgtatg ggacgtaccg tttacggagg tggaggtatc
     7741 atgcccgact tcttcgtccc catcgacact acccagtaca cagactatca ccgcaacctc
     7801 gtagccaaag gcgtggttat caaagccact accggctaca tcgagaagca ccggaaggag
     7861 ttgcagaaca aatacaagag attcgaagcc ttcaacgaga agttcgagat agacgataac
     7921 ttccttgccg aaatacgtac gcttgccgac aaagagaaaa tcaagtttga cgagaaacag
     7981 tacaaccaat ccctaccgct catcaagaca caacttaaag ccttgatagc ccgtgaccta
     8041 tgggacatga acgaatactt ccaggtgatg aacagcacga accagagcgt gcagcaagct
     8101 ctaaaagtgc tgaacgaagg catctacagc actattatcc aatagccgac ttgaaacaaa
     8161 cttaggcgcg gattatgcgg atttagttta tctaactccg cgtattccgc gtaattcgcg
     8221 cctaaaatca ttctccgaac agccacttat tcagccactt gttgacgtag atgttgacca
     8281 cagcacatcc agcaccgatt gcagcccccg ccaacacatc tgacggataa tgcactccct
     8341 cgttcatacg ggaaactccc acggaacaag cccacagggc agacggagct atcacatacc
     8401 atttaggata ctttacactg agcgaggtgg caagggcaaa agccgtcgcc gtatgtccag
     8461 aaggaaaaga cgggctgcct tcatggctat atgcatgcac tctgtcggga tatttatcat
     8521 aaggacgctc acggtccacc agatatttca ttccataagt cacaacaaaa gcccccgcta
     8581 cacttgtacc tacgtagacc gcatctttca gcaaaccctt atcatgtttt atccaagcgg
     8641 caaccgccat cgccaccgga acaccgacag caacataggg ctccgaacgt gaaattatct
     8701 tattatagtt acggacaaac ttgccatccc aactgttaac ccggtgcaaa gtgttaatat
     8761 cccaattctg tgccgaaaga ccggatacaa caaggcagat aaaatataca aaaaaaatag
     8821 cctttttcat aagtccttta tattagtttg acgcaaagat aggacaaata gatagagttt
     8881 tcacaaaaaa attctatctt tgttgccaca tttataataa ttcgctaatc atttcatgag
     8941 actggaaact tgctgcaacc gacagattga ttgtatggta tgtccccaaa aatcagaagg
     9001 agtattggtt taccgccact accccaaggg acaacatttc tctgctgaaa agtgcacaca
     9061 gaacagcatg atatttatgc tgaaaggtga attacttgta aacagtgacg aatatccggg
     9121 caccactctc caaagccgcc agctcatctt gcaagccatc ggctccaaag tagaactcct
     9181 ggctttgacc gaagtggaat atattgtgta ttggttcacc gagcttcctc tgatttgcga
     9241 agagcgctac aaggagatac tgaaacgctc ggaagccccc ttgacttata ccccgcttac
     9301 cgcgatttcc atgctcgaag ggctcctgaa aagccttgcc tgctacctca acgagcaacc
     9361 ctatgcgtgc agcaaataca ttgaaatgaa atgccaggaa ttggtataca tattgacatg
     9421 ctactatccg ctacaccaaa tcagtacatt cttctacccc atcagcactt atacggaaag
     9481 cttccaatat ttcgtcatgc agaactacga caaggtgaag aatgtggaag agtttgccca
     9541 cctcggtgga tataccacca ccacattccg ccgtctgttt aaaaatatgt atggggtccc
     9601 ggtctatgaa tggattctgg acaagaaacg tgaaggaatt ctgaacgacc tgcaatacac
     9661 caaacaacgc atttcagtca tcagcgcccg ctatggcttt gattccctat cccactttgc
     9721 ccacttctgc aaagactctt tcggagacac gccccgcgcc ctgagaaaac gttcggcaaa
     9781 cggagaaaag atttccatta tctgcaaaga gcaaggcaaa gaccaggagg acgagtaaac
     9841 cttttacttg tccgtaaact tcgcattctg ccggattacg gaattatttc tttaatcgct
     9901 tgctttatcg ctggatttct cctatttttg cgaaacattt acagaagtat cctgatagaa
     9961 caaattttca aactattaaa taacttaaat tcaatcattt atgtggttaa gtaattcatc
    10021 tgtaggaagg aaagtggtga tgagcgttac cggtatcgcc cttgtcctgt ttctgacatt
    10081 tcacatggcg atgaacctgg ttgcattagt ctcggctaat ggctacaaca tggtttgtga
    10141 gttcctggga gcaaactggt acgcattggt ggctacggta ggtctggctg ccttattcat
    10201 catccacatc atctacgctt tctggctgac tatgcagaac cgtaaggcac gtggtagcga
    10261 acgctatgcc gttacggaaa agcccaagac tgtggaatgg gcttctcaga acatgctcgt
    10321 actgggtatc atcgtaatcg tgggtttggg cctgcacctg gtaaacttct gggctaaaat
    10381 gcagcttccc gagttgatgc acaacatggg catgcatgcc gacaccctca cgctggcata
    10441 tgcagccaac ggtgtctatc acattcaaaa caccttcagc aatccggtat tcgtagtgct
    10501 ttacctcgtt tggctgggcg cattgtggtt ccacctcact cacggtttct ggagctccat
    10561 gcagtctttg ggatggaaca acaaagtatg gattaaccgt tggaaatgta tctccaacat
    10621 ctattctact atcgttgtcc tctgcttcgc tctggtagtt gtcgtattct ttgcaaaatc
    10681 attgtgcggc gcttgctaaa ttcaaattgt aaatgactaa attgtaaatt gcattatgac
    10741 taagatagat tctaaaatac cggaaggacc ggtggctgag aaatggacca attataaggc
    10801 tcaccaaaaa ttagtaaacc ctgccaacaa acgtcgtctg gacatcatcg tagtaggaac
    10861 cggacttgcc ggtgccagtg ctgccgcctc tctgggcgaa atgggtttca gagtattcaa
    10921 cttctgcatc caggactctc cgcgccgtgc acactccatc gctgcacaag gtggcatcaa
    10981 tgctgctaag aattaccaaa acgacggtga ctctgtatac cgtctgttct acgatacagt
    11041 aaagggtggc gactaccgtg cccgcgaagc caacgtttac cgtctggctg aagtatccaa
    11101 caatattatc gaccaatgcg ttgcacaagg tgttcctttc gcccgcgaat acggcggtac
    11161 actggacaac cgttctttcg gtggtgctca ggtatcccgt actttctatg ccaagggtca
    11221 gaccggacag cagctgttgc tgggtgcata ctctgcattg agccgccagg tgaacgtagg
    11281 cactgtgaaa ctgtataccc gctacgaaat ggaagacgtt gtcctcattg acggacgtgc
    11341 ccgcggtatc attgcaaaga acctcgttac cggtaaattg gaacgttttg ccgcccacgc
    11401 tgtggtaatc gctaccggtg gttacggcaa tgcctacttc ctttctacca atgcaatggc
    11461 atgtaactgc tctgcagcaa tggcttgcta ccgtaaaggt gcctggtttg ccaaccctgc
    11521 ttacgtacag attcacccca cttgtatccc ggttcacggt gacaagcaat ctaagctgac
    11581 tttgatgtcc gaatctctgc gtaacgatgg tcgtatctgg gttccgaaga agctggaaga
    11641 tgccaagaaa ctgcaggaag gtacactgca aggaaaagat attcccgagg aagaccgcga
    11701 ctactacctg gaacgccgtt atccggcatt cggtaacctc gttccgcgtg acgttgccag
    11761 ccgcgctgcc aaagaacgct gcgacaaggg cttcggcgtg aacaacaccg gtcttgccgt
    11821 attccttgac ttctccgaag ctatcaaccg tctgggtaaa gatgtcgttg cacaacgtta
    11881 cggcaacctc ttcgatatgt atgaagaaat cactgatgtc agcccatacg aaaacccgat
    11941 gatgatttat ccggctatcc actataccat gggtggtatc tgggttgact acgaactgat
    12001 gacctccatc aagggactgt tcgccatcgg tgaatgtaac ttctccgacc acggtgcaaa
    12061 ccgcctcggt gcttccgccc tgatgcaagg tctggccgat ggttacttcg tattgcctta
    12121 cactatccag aactatctgg ccgaccagat tacagttccc cgtttctcta ccgacctgcc
    12181 cgaatttgca gctgcagaaa aggccgttca ggagaagatt gactggatga tgaacatcaa
    12241 gggtaagaag tctgtagact ctatccacaa ggaactgggc cacattatgt gggaatatgt
    12301 aggtatggga cgtacggccg aaggcttgaa ggaaggtctg aagaagctga aagaagtccg
    12361 caaggagttc gagaaagaac tgttcatccc gggcgacaag gaaggtatga atgtagaact
    12421 cgacaaggct atccgtctgt acgacttcat cactatgggc gagctggttg cttacgatgc
    12481 actgaaccgt aacgaaagct gcggcggtca cttccgtgaa gaatatcaga ctgaagaagg
    12541 cgaagccaag cgtgacgatg aaaactactt ctacgtggct tgctgggaat atcagggttc
    12601 tgacgaaaag gaaccggtat tgctgaaaga gccgctggtt tacgaagcaa tcaaggtaca
    12661 gactcgtaac tacaagagct aatcgggaag ttgaacattt aaagaattaa agaaaatgga
    12721 taaaaatata tcatttacgc tcaaggtatg gcgccagaag ggtccgaaag caaaaggcgc
    12781 ttttgaaaca taccaaatga aagatatccc gggcgatact tcattcctcg aaatgctgga
    12841 tatcttgaac gaacagctga tttctgaagg taaagaaccg gttgtattcg accacgactg
    12901 ccgcgaaggt atctgcggta tgtgttcgct ctacatcaac ggacatcccc acggtcctgc
    12961 aaccggcgct acgacttgcc agatttatat gcgtcgtttc aacgacggcg ataccatcac
    13021 tgttgaaccg tggcgctctg ccggtttccc ggttatcaag gacttgatgg tcgaccgtac
    13081 ggcctacgac aagattatgc aggcaggcgg ctacgtcagc gtacgtaccg gtgctcccca
    13141 ggatgccaac gctatcctga ttccaaagcc catcgctgac gaggctatgg atgctgccag
    13201 ctgtattggt tgtggtgctt gtgtggctgc ttgtaagaac ggttctgcca tgttgttcgt
    13261 ttctgccaag gtgagccagc tgaacctgtt gccccaaggc aaaccggaag cattgcgccg
    13321 tgccaaggct atgttgagca agatggacga actcggtttc ggtaactgta caaacactcg
    13381 tgcgtgcgaa gctgaatgcc cgaagaatgt ttccatcagc aacattgccc gcctgaaccg
    13441 cgactttatc attgcgaaac tgaaagacta atccggtctt tctgcaaata atataggatg
    13501 cgcttcggat aaaccttctg agcaagctca gatttatcac tcagctttca ctatatttga
    13561 ttaatatcac aagagactcc tctgccggga aaccgccgga ggagtttttt tatgacatgc
    13621 cgtttacttc agataaattg ccggcacgca agctacgggg agaagccccg aaattctttt
    13681 tgcagaaatt ggaaaaatga ggcagcgatt caaagccata tttatagcaa atctctgata
    13741 tagaagcatc cgtataacga agttcataaa ccacgctttc cttcctccgt tccatcatcc
    13801 actcgtacac cggttgatga aaaacagaat tgaatatacg ccggaaagta gctactgtat
    13861 atcctcccaa ctgggcaagt tcctctaccg tcttgacttt ggcatgattc tgcaagacaa
    13921 agtagtggaa ggaattagta tactgggcaa gaggatgtat cagcatggaa agctcatagt
    13981 cggagtagta atttccaaga atgaaagcaa gttctttccg tttgaaacaa agcatttccc
    14041 ggcaaatctt ctcctcggac aaataggcct tggaactttc cagaaagagc tgcaactcgg
    14101 gagtaatggt caaaggatag aatatcaatg gaggggtaac ctctttcata atatggttat
    14161 accggtcctc acagaagaat tcaggcttac tgaaccggta acaaacgcat tccacatccg
    14221 tcatggcaag tatttcgtac ttggaaccaa tagcttgaag gatgaactca cctgcatgca
    14281 acacagttcc cgcatactcc ttactgttga caagcacttc tcctttcagc aggaaaatta
    14341 taatattttc ctcacacttt cgcgccggca gatggaatcc tctgaggtgg gaagcatata
    14401 ttattgcatt gtccacagcc ttgggacatt gagcgcattg ttttttacct ctgcaagcag
    14461 aagagttggg catcggcaag tagatttgtt tgtttgttgc agtgacaaaa atagataaat
    14521 aatactcata aaagaaacat tccccgaaaa ctttcataaa gaagtttcgg ggaatgaata
    14581 aaatagaagt aattcagttt tttattgcgg acagtgccgt tttatttttc cacgttcgta
    14641 tcatcagccg tactccatgg accaacttca ggtacaaagg ttacttttgc cgccttattg
    14701 gccagcgtca gcgtataacg tatctttttg ccttcacccc aggcttgtgt atcattcaag
    14761 tcaatggcgg aagttacagt atcaagaaga acgtctttct catagatgtc atagacaaca
    14821 ttgattttgg cattcgtatc caacgtctgg ggcatcaaca tccaggctgc attcatttcc
    14881 acacccgttg tattcacttc caatgcactg ccggcaatcg tatgcgcata agtggctgtt
    14941 ccttcttgtg acttccatgt tgaatcatca aaaccataag ttcccttatt gtgcacgccg
    15001 gatattgtaa gtgttttcag tttataagtc aaagcgtcgg ctgccttgac agtgaaattt
    15061 atttgggtca gtatatggcc gaatttcaaa gataccccac tggcatttga tgccttggtt
    15121 gcatccgtca ctttcgcggc taccaagtcc gtttgggcag ctacatctgc taccgtataa
    15181 gtaatggaag gatatatagc accagcagcc ggttgattgt acgtcaaggc tccggtaccc
    15241 ggattcccgt aagcaaagaa ctgcaagtta tccgtcattg gccaataata tgttccccca
    15301 gtcaaactcc agtcgggagc actataggtt actttaacat ctgtcatgaa ttccttcatc
    15361 gcatcaaaag tcgcaacgga ggccattgct gtcgctcccg tattataagc atacacagtg
    15421 aaccctacct tctgcaattc cggcaaatca gtcactgtgg ctctcgtagt gttacccact
    15481 actgttccca atttaatctc cgccttttgt ccggcattct ctatctcctc actttccgag
    15541 caactcatta ctgctgctgc agccaaagcc aaaaataaaa ccttcttcat aattgtctgt
    15601 tattaaagtt aatatattta tttgtctgtt tgctatcaat tcaccggtag ctccacatcc
    15661 gtctcatcat cccaatcatc cacatcgcca ccaatccctc catctccttc atcggttccc
    15721 ggttccaaat catccaccac aaccttgtcc tccggtacgg gaacctcgat atggatttcc
    15781 gacccaggaa cgcccacatc aggttcttct tcgcctcctc ctgagggagg agctgtttca
    15841 atcacttccg tgatatccac cttcacctct tgaaccgttt tatctcgttt cacaatcttc
    15901 agtgtcagca acataggact atccgcacgg gtcttggtat ctttcagtaa tacaaaactg
    15961 gagaaatacc cccataaaag cccgttttca cgctttgtat ccacacatat aggtacctcg
    16021 ctcaaatggc aagcacggtt gcctataaag taacttccgt tcaagccgtc cacatggcag
    16081 atgatgctcg atattctatc ccatccttcc acctttatat caaaggaata atggtccact
    16141 accgcttccg gcttccagtt caacggaagc gccacatcac tctgccttat ttccacctcg
    16201 tccaaagcca ccacatacaa agggtcgggc gaccaaacca tatcttcgtg tacatccagc
    16261 cccgtacagt gtcccgtaaa agcctcaatc gtctcataac tctcgtcgcc ccgtatctgt
    16321 atactctccg tattgaagtt ataggccacc accgcatact tccccggcgg taccttcacc
    16381 tcaccccctc cggcaggcag ataactttca acctttctcc cctgagtatc tttcggatag
    16441 aagataatcc gcatggtctg cggcagctta tccgtcaccc ctttccaatc cagtttaatc
    16501 tgtactccgc taacgggata atcatccagc atatcgcgga agtcacagct tcccagcatt
    16561 ggcaacagcc cgaagaacag ccagagaatc atatgccgtg catctttcat accactcatc
    16621 tccccgacgt tagaaaccac accaaagaaa cttttgcttt tgtcggcccg ataaagtgat
    16681 actttccaca gctgacccaa accaagtcat ttccataaga agtatatttc ctgtactccg
    16741 tatccaagta tccaatgccc acactgaatt caatcgccag atgccgagcc agtggacgca
    16801 cgtatccata agttattcct gcagctgcgt aatacttccc ccggtatccc ttctcctttt
    16861 tcaactgaaa atcataggta cctccttcgg catatgctcc caggaagtgt ccggacaatc
    16921 ttccgcgcgt atggcggttt cccaaccagt aacgcgcctc tgtccctccc gaaaggagct
    16981 gatagcaaaa attacatccg ctgtcagacc accaagggca tttgtactca acattcaaag
    17041 accacctctt tcccaatggc agctccactt ctatgttcgg agccaaggcc aggtcgtaaa
    17101 gcaacttatt ttttaacgcc agcaccgttt tacaagtatg gctatgggat tctaccgact
    17161 tattctgccc tattacctgc cccgacatca tgcaaaaaag gagtagccaa aagacatata
    17221 taaaaatgcg ttttcccata atttcgcgtt gtatacaaac aaaagtagaa gataattacc
    17281 gaataaaaat cactttccat cactcttttc aaaggctgaa aggttctgtg aaacgattga
    17341 aacagatttg caacttctgc cttatccggg acgctgtgaa tagattcttc tctctcaaaa
    17401 agtcaatccg tgtgcgaaaa cagtaaaatt cagtgaaaga aatacaaaag aagtagcagg
    17461 aacattctga aatttggaag ataacaacgg gaaccttaca tttgtaatgt gatttttttc
    17521 atagtattag atttaaggtt aacaaaggtt ggagtacagc ggtactcct
//
