## Tue Jul  9 21:06:50 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_036816305.1/GCA_036816305.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_036816305.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_036816305.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
IHAFMDNN_00001	585394.RHOM_07265	1.08e-250	701.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
IHAFMDNN_00002	585394.RHOM_07265	1.24e-24	102.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
IHAFMDNN_00003	585394.RHOM_07270	0.0	994.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
IHAFMDNN_00004	585394.RHOM_07275	7.8e-38	127.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
IHAFMDNN_00005	585394.RHOM_07295	9.78e-260	713.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
IHAFMDNN_00006	665956.HMPREF1032_02998	3.76e-60	199.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IHAFMDNN_00007	585394.RHOM_07300	0.0	981.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
IHAFMDNN_00008	622312.ROSEINA2194_04359	9.24e-33	115.0	2EC2U@1|root,3361T@2|Bacteria,1VK1M@1239|Firmicutes,24RW0@186801|Clostridia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
IHAFMDNN_00009	622312.ROSEINA2194_04360	1.34e-68	210.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
IHAFMDNN_00010	585394.RHOM_16055	2.02e-154	436.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
IHAFMDNN_00011	1235802.C823_01323	1.62e-44	145.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
IHAFMDNN_00012	585394.RHOM_16045	4.29e-44	150.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
IHAFMDNN_00013	622312.ROSEINA2194_04364	5.73e-101	296.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
IHAFMDNN_00014	622312.ROSEINA2194_04365	0.0	926.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
IHAFMDNN_00015	585394.RHOM_16030	1.41e-159	452.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
IHAFMDNN_00016	622312.ROSEINA2194_04367	0.0	866.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
IHAFMDNN_00017	622312.ROSEINA2194_04368	8.76e-80	238.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
IHAFMDNN_00018	622312.ROSEINA2194_03516	8.33e-250	694.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00019	1235793.C809_01250	6.17e-13	72.4	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,27MRG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
IHAFMDNN_00022	622312.ROSEINA2194_03155	6.02e-105	310.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
IHAFMDNN_00023	622312.ROSEINA2194_03156	7.17e-235	647.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
IHAFMDNN_00024	585394.RHOM_02890	1.75e-74	229.0	2CB94@1|root,32XMH@2|Bacteria,1VCD1@1239|Firmicutes,24MX5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00025	622312.ROSEINA2194_03158	9.83e-190	530.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
IHAFMDNN_00026	585394.RHOM_02880	7.57e-26	97.4	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00027	622312.ROSEINA2194_03159	8.64e-73	221.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
IHAFMDNN_00028	622312.ROSEINA2194_03160	1.82e-129	372.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
IHAFMDNN_00029	622312.ROSEINA2194_03161	1.54e-89	263.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia	186801|Clostridia	K	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
IHAFMDNN_00030	622312.ROSEINA2194_03162	2.43e-65	204.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
IHAFMDNN_00031	622312.ROSEINA2194_00823	1.66e-113	329.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
IHAFMDNN_00032	622312.ROSEINA2194_00824	0.0	912.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
IHAFMDNN_00033	622312.ROSEINA2194_02050	1.59e-65	199.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
IHAFMDNN_00034	622312.ROSEINA2194_02051	9.66e-151	425.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
IHAFMDNN_00035	622312.ROSEINA2194_02052	1.43e-128	367.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
IHAFMDNN_00036	585394.RHOM_14605	1.07e-58	182.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
IHAFMDNN_00037	585394.RHOM_14600	2.06e-197	547.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
IHAFMDNN_00038	622312.ROSEINA2194_02055	4.17e-60	185.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
IHAFMDNN_00039	622312.ROSEINA2194_02056	7.16e-82	243.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
IHAFMDNN_00040	585394.RHOM_14585	1.69e-151	426.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
IHAFMDNN_00041	622312.ROSEINA2194_02058	2.11e-98	286.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
IHAFMDNN_00042	585394.RHOM_14575	5.47e-34	117.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
IHAFMDNN_00043	622312.ROSEINA2194_02060	3.48e-53	167.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
IHAFMDNN_00044	585394.RHOM_14565	2.87e-76	228.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
IHAFMDNN_00045	1235790.C805_00242	7.38e-61	187.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25WQ0@186806|Eubacteriaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
IHAFMDNN_00046	585394.RHOM_14555	9.01e-121	345.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
IHAFMDNN_00047	585394.RHOM_14550	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
IHAFMDNN_00048	585394.RHOM_14545	2.87e-88	259.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
IHAFMDNN_00049	585394.RHOM_14535	7.41e-120	343.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
IHAFMDNN_00051	585394.RHOM_12375	3.25e-252	692.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
IHAFMDNN_00052	585394.RHOM_12370	5.25e-201	557.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
IHAFMDNN_00053	585394.RHOM_12365	5.1e-125	357.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
IHAFMDNN_00054	585394.RHOM_12360	3.2e-137	395.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
IHAFMDNN_00055	585394.RHOM_12355	6.56e-264	728.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
IHAFMDNN_00056	1235790.C805_00459	3.07e-103	338.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,25Y5N@186806|Eubacteriaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
IHAFMDNN_00057	585394.RHOM_12340	8.8e-282	777.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
IHAFMDNN_00058	515620.EUBELI_00156	6.7e-253	702.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00059	585394.RHOM_03315	0.0	965.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
IHAFMDNN_00060	622312.ROSEINA2194_04415	6.74e-200	556.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
IHAFMDNN_00061	585394.RHOM_03305	5.31e-134	380.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
IHAFMDNN_00062	585394.RHOM_03300	0.0	1166.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
IHAFMDNN_00063	585394.RHOM_03295	6.72e-269	740.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
IHAFMDNN_00064	585394.RHOM_03290	6.78e-127	362.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
IHAFMDNN_00065	1121335.Clst_1077	0.0	1123.0	COG2182@1|root,COG2182@2|Bacteria,1UJPM@1239|Firmicutes,25F7T@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
IHAFMDNN_00066	1449050.JNLE01000003_gene2908	1.28e-157	450.0	COG1175@1|root,COG1175@2|Bacteria,1TR0M@1239|Firmicutes,24CRB@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IHAFMDNN_00067	1121335.Clst_1079	5.51e-156	444.0	COG0395@1|root,COG0395@2|Bacteria,1TRS1@1239|Firmicutes,24ARW@186801|Clostridia,3WH53@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
IHAFMDNN_00068	1094508.Tsac_1160	1.06e-173	504.0	COG3391@1|root,COG3391@2|Bacteria,1U3IC@1239|Firmicutes,2490J@186801|Clostridia,42I05@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Yip1
IHAFMDNN_00069	1121335.Clst_1081	1.54e-67	213.0	COG2881@1|root,COG2881@2|Bacteria,1VBWZ@1239|Firmicutes,24MD2@186801|Clostridia	186801|Clostridia	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
IHAFMDNN_00070	622312.ROSEINA2194_04145	0.0	2296.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
IHAFMDNN_00071	585394.RHOM_04830	0.0	1102.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,SBP_bac_3
IHAFMDNN_00072	585394.RHOM_04825	0.0	1023.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
IHAFMDNN_00073	585394.RHOM_03935	1.59e-248	689.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
IHAFMDNN_00074	622312.ROSEINA2194_03375	1.69e-113	332.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
IHAFMDNN_00075	622312.ROSEINA2194_03374	0.0	879.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
IHAFMDNN_00077	585394.RHOM_03955	3.67e-180	506.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
IHAFMDNN_00078	585394.RHOM_03960	8.88e-128	379.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia	186801|Clostridia	S	Secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
IHAFMDNN_00079	585394.RHOM_03965	0.0	948.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
IHAFMDNN_00080	622312.ROSEINA2194_03404	3.1e-137	394.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
IHAFMDNN_00081	622312.ROSEINA2194_03403	7.82e-129	369.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia	186801|Clostridia	K	domain protein	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IHAFMDNN_00082	585394.RHOM_11785	3.68e-293	807.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia	186801|Clostridia	EG	GerA spore germination protein	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
IHAFMDNN_00083	585394.RHOM_11780	1.68e-214	624.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25DGZ@186801|Clostridia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
IHAFMDNN_00084	622312.ROSEINA2194_03400	5.77e-71	222.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia	186801|Clostridia	S	stage ii sporulation protein r	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
IHAFMDNN_00085	397290.C810_01003	1.51e-71	218.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,27N6U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
IHAFMDNN_00086	585394.RHOM_11895	1.89e-294	806.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N
IHAFMDNN_00087	585394.RHOM_11890	2.67e-144	412.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
IHAFMDNN_00088	397291.C804_02341	2.88e-77	243.0	COG0127@1|root,COG0127@2|Bacteria,1V85S@1239|Firmicutes,24KX4@186801|Clostridia,27NVI@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Ham1 family	-	-	-	-	-	-	-	-	-	-	-	-	Ham1p_like
IHAFMDNN_00089	511680.BUTYVIB_00807	5.12e-77	233.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,4BZAJ@830|Butyrivibrio	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
IHAFMDNN_00090	585394.RHOM_03230	0.0	1043.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00091	585394.RHOM_03220	0.0	904.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00092	1280698.AUJS01000061_gene1112	3.71e-100	296.0	COG1403@1|root,COG1403@2|Bacteria,1V5KT@1239|Firmicutes,24N2K@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00093	457421.CBFG_05938	4.01e-156	454.0	COG3950@1|root,COG3950@2|Bacteria,1UJJK@1239|Firmicutes,24CJD@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
IHAFMDNN_00094	622312.ROSEINA2194_01607	1.28e-241	665.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
IHAFMDNN_00095	585394.RHOM_02670	1.46e-72	225.0	COG1971@1|root,COG1971@2|Bacteria,1V25U@1239|Firmicutes	1239|Firmicutes	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
IHAFMDNN_00096	658086.HMPREF0994_00444	5.94e-29	108.0	COG2198@1|root,COG2198@2|Bacteria,1VG8R@1239|Firmicutes,24JZF@186801|Clostridia,27PU8@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
IHAFMDNN_00097	622312.ROSEINA2194_01595	4.29e-236	655.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
IHAFMDNN_00098	585394.RHOM_02635	2.15e-83	248.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
IHAFMDNN_00099	585394.RHOM_02630	3.29e-42	153.0	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
IHAFMDNN_00100	585394.RHOM_02625	9.99e-162	465.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia	186801|Clostridia	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00101	585394.RHOM_02620	3.68e-195	554.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
IHAFMDNN_00102	622312.ROSEINA2194_03131	4.39e-152	436.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IHAFMDNN_00103	622312.ROSEINA2194_03130	2e-92	271.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia	186801|Clostridia	C	assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
IHAFMDNN_00104	1298920.KI911353_gene3328	2.19e-265	732.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,21XFB@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	MET17	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IHAFMDNN_00105	1341157.RF007C_10565	1.93e-173	489.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
IHAFMDNN_00106	585394.RHOM_13855	3.19e-95	282.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
IHAFMDNN_00107	585394.RHOM_13850	3.79e-205	576.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
IHAFMDNN_00108	877424.ATWC01000015_gene633	9.78e-133	389.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,27IRU@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
IHAFMDNN_00109	622312.ROSEINA2194_02885	1.61e-203	571.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
IHAFMDNN_00110	397287.C807_00219	2.66e-83	254.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,27U4Q@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT,Response_reg
IHAFMDNN_00111	585394.RHOM_11560	2.39e-240	676.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
IHAFMDNN_00112	585394.RHOM_11415	9.04e-117	355.0	COG0840@1|root,COG0840@2|Bacteria,1TQW8@1239|Firmicutes,24EE8@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
IHAFMDNN_00113	556261.HMPREF0240_00860	8.09e-152	454.0	COG2199@1|root,COG2199@2|Bacteria,1TQKY@1239|Firmicutes,25EP8@186801|Clostridia,36V2W@31979|Clostridiaceae	186801|Clostridia	T	Pfam:Cache_1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
IHAFMDNN_00114	622312.ROSEINA2194_02159	9.99e-99	294.0	COG2186@1|root,COG2186@2|Bacteria,1V1Y0@1239|Firmicutes,249UW@186801|Clostridia	186801|Clostridia	K	FCD domain	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
IHAFMDNN_00115	585394.RHOM_04720	1.11e-155	452.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00116	411461.DORFOR_03011	3.48e-87	260.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
IHAFMDNN_00117	585394.RHOM_16785	2.14e-277	764.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00118	1280688.AUJB01000009_gene1639	1.34e-15	88.2	2EAR0@1|root,334T8@2|Bacteria,1VAT6@1239|Firmicutes,24NCB@186801|Clostridia,3NGVW@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00119	622312.ROSEINA2194_04314	1.53e-234	652.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
IHAFMDNN_00121	622312.ROSEINA2194_04317	1.13e-137	390.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
IHAFMDNN_00122	585394.RHOM_16745	4.46e-208	590.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IHAFMDNN_00123	1163671.JAGI01000003_gene928	9.97e-57	185.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia,36GXV@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_00124	1298920.KI911353_gene1189	2.75e-146	418.0	COG0395@1|root,COG0395@2|Bacteria,1TSX2@1239|Firmicutes,24891@186801|Clostridia,222N7@1506553|Lachnoclostridium	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_00125	1280668.ATVT01000001_gene794	6.9e-94	281.0	COG2755@1|root,COG2755@2|Bacteria,1V2SC@1239|Firmicutes,24H62@186801|Clostridia,4BWRN@830|Butyrivibrio	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IHAFMDNN_00126	515622.bpr_I1585	4.78e-210	601.0	COG3507@1|root,COG3507@2|Bacteria,1UDW2@1239|Firmicutes,24A81@186801|Clostridia,4BYGR@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
IHAFMDNN_00127	483218.BACPEC_01722	2.45e-275	774.0	COG0666@1|root,COG3507@1|root,COG0666@2|Bacteria,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,26AET@186813|unclassified Clostridiales	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Ank_2,Ank_4,Glyco_hydro_43
IHAFMDNN_00129	585394.RHOM_08175	4.71e-267	743.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
IHAFMDNN_00130	585394.RHOM_08170	4.03e-166	469.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
IHAFMDNN_00131	622312.ROSEINA2194_02777	3.85e-101	301.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
IHAFMDNN_00132	585394.RHOM_04945	0.0	897.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia	186801|Clostridia	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
IHAFMDNN_00133	585394.RHOM_04940	7.36e-95	285.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
IHAFMDNN_00134	585394.RHOM_04935	2.13e-238	661.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
IHAFMDNN_00135	622312.ROSEINA2194_03431	0.0	934.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
IHAFMDNN_00136	585394.RHOM_04925	3.56e-217	602.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
IHAFMDNN_00137	585394.RHOM_01040	9.5e-192	537.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia	186801|Clostridia	KT	PFAM Region found in RelA SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
IHAFMDNN_00138	877424.ATWC01000015_gene634	1.37e-20	98.6	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,27ISK@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,Hpt,Response_reg
IHAFMDNN_00139	877424.ATWC01000015_gene635	3.06e-265	768.0	COG0642@1|root,COG0784@1|root,COG1307@1|root,COG0784@2|Bacteria,COG1307@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DegV,HATPase_c,HisKA,Hpt,Response_reg
IHAFMDNN_00140	1321778.HMPREF1982_03315	2.39e-160	460.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,26A16@186813|unclassified Clostridiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
IHAFMDNN_00141	1341157.RF007C_08915	5.35e-89	268.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
IHAFMDNN_00142	1321778.HMPREF1982_03317	9.58e-242	669.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,26AE5@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
IHAFMDNN_00143	1410633.JHWR01000016_gene1040	1.13e-84	252.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,27M62@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
IHAFMDNN_00144	585394.RHOM_14415	7.6e-76	228.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IHAFMDNN_00145	585394.RHOM_13060	6.54e-97	311.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
IHAFMDNN_00146	622312.ROSEINA2194_01957	5.24e-92	285.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00147	585394.RHOM_14405	1.02e-76	235.0	COG1670@1|root,COG1670@2|Bacteria,1V1ZC@1239|Firmicutes,249K2@186801|Clostridia	186801|Clostridia	J	Acetyltransferase GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
IHAFMDNN_00148	585394.RHOM_14400	1.41e-97	285.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
IHAFMDNN_00149	1235790.C805_03317	2.21e-29	112.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,25XG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
IHAFMDNN_00150	585394.RHOM_14390	2.66e-223	617.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
IHAFMDNN_00151	585394.RHOM_14385	7.51e-255	706.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00152	622312.ROSEINA2194_03462	1.79e-67	215.0	28MTH@1|root,2ZB1P@2|Bacteria,1UYJE@1239|Firmicutes,24D9M@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF4007)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4007
IHAFMDNN_00153	622312.ROSEINA2194_03461	0.0	1221.0	COG0262@1|root,COG0262@2|Bacteria,1UIN4@1239|Firmicutes,25ENR@186801|Clostridia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00154	622312.ROSEINA2194_03460	3.88e-168	482.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia	186801|Clostridia	E	Cysteine desulfurase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
IHAFMDNN_00155	97139.C824_00955	4.31e-284	803.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1U5K1@1239|Firmicutes,24A01@186801|Clostridia,36I99@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
IHAFMDNN_00157	585394.RHOM_03340	2.75e-101	299.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IHAFMDNN_00159	585394.RHOM_03360	0.0	1457.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
IHAFMDNN_00160	585394.RHOM_03370	0.0	1732.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
IHAFMDNN_00161	1280390.CBQR020000094_gene2070	2.58e-104	310.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,4HIDF@91061|Bacilli,276ZZ@186822|Paenibacillaceae	91061|Bacilli	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
IHAFMDNN_00162	1235793.C809_02443	5.79e-50	167.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,27M8T@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
IHAFMDNN_00163	877420.ATVW01000017_gene1701	7.54e-139	407.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,27IYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
IHAFMDNN_00164	1280390.CBQR020000094_gene2073	9.59e-254	709.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,4HAQW@91061|Bacilli,26UJH@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
IHAFMDNN_00165	1280685.AUKC01000023_gene851	1.44e-192	558.0	COG1653@1|root,COG1653@2|Bacteria,1TQ1D@1239|Firmicutes,24AFW@186801|Clostridia,4BXI8@830|Butyrivibrio	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IHAFMDNN_00166	573061.Clocel_0036	8.6e-122	379.0	COG2972@1|root,COG2972@2|Bacteria,1UY73@1239|Firmicutes,24AX8@186801|Clostridia,36G3Y@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
IHAFMDNN_00167	515622.bpr_I1350	7.97e-128	367.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,4BXWJ@830|Butyrivibrio	186801|Clostridia	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
IHAFMDNN_00168	665956.HMPREF1032_02341	0.0	1468.0	COG0493@1|root,COG1143@1|root,COG4231@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,COG4231@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WHYH@541000|Ruminococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
IHAFMDNN_00169	515622.bpr_I1351	3.56e-52	167.0	COG0375@1|root,COG0375@2|Bacteria,1VABW@1239|Firmicutes,24NES@186801|Clostridia,4BZG4@830|Butyrivibrio	186801|Clostridia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
IHAFMDNN_00170	585394.RHOM_04670	5.81e-42	138.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00171	585394.RHOM_04675	3.23e-192	541.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
IHAFMDNN_00172	585394.RHOM_04680	0.0	892.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
IHAFMDNN_00173	585394.RHOM_14460	8.48e-216	597.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
IHAFMDNN_00174	585394.RHOM_14465	1.58e-132	376.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
IHAFMDNN_00175	140626.JHWB01000013_gene268	1.94e-76	229.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
IHAFMDNN_00176	140626.JHWB01000013_gene267	2.27e-73	221.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
IHAFMDNN_00178	585394.RHOM_14490	6.91e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
IHAFMDNN_00179	397288.C806_00699	1.21e-18	80.1	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24UP0@186801|Clostridia	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00180	585394.RHOM_14500	2.38e-154	437.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
IHAFMDNN_00181	622312.ROSEINA2194_02071	1.63e-147	416.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
IHAFMDNN_00182	585394.RHOM_14510	3.47e-276	760.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
IHAFMDNN_00183	622312.ROSEINA2194_02069	9.85e-10	58.2	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
IHAFMDNN_00184	585394.RHOM_14520	3.04e-32	112.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
IHAFMDNN_00185	585394.RHOM_14525	1.84e-106	308.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
IHAFMDNN_00186	1282887.AUJG01000003_gene406	2.33e-42	140.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
IHAFMDNN_00187	622312.ROSEINA2194_01939	3.29e-42	147.0	2DSWH@1|root,32UTX@2|Bacteria,1VBEP@1239|Firmicutes,24PR0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00188	1235802.C823_02421	2.69e-136	389.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00189	622312.ROSEINA2194_01937	3.1e-253	707.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_00190	1235790.C805_02256	1.08e-26	110.0	2C0VN@1|root,32VTP@2|Bacteria,1VAWW@1239|Firmicutes,24N54@186801|Clostridia,25XSI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
IHAFMDNN_00192	585394.RHOM_11275	3.8e-199	553.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia	186801|Clostridia	T	response regulator receiver	cheV	-	2.7.13.3	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,Response_reg
IHAFMDNN_00193	622312.ROSEINA2194_01934	8.12e-41	160.0	2DM0G@1|root,31677@2|Bacteria,1UIGR@1239|Firmicutes,25EN6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00194	622312.ROSEINA2194_01933	1.52e-116	336.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IHAFMDNN_00195	622312.ROSEINA2194_01932	1.87e-170	477.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IHAFMDNN_00196	622312.ROSEINA2194_01931	7.45e-157	441.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
IHAFMDNN_00197	622312.ROSEINA2194_01336	7.32e-317	873.0	COG4870@1|root,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,248WA@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,Peptidase_C1,Rhodanese
IHAFMDNN_00198	585394.RHOM_02930	2.57e-258	710.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
IHAFMDNN_00199	585394.RHOM_02925	3.04e-38	130.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
IHAFMDNN_00201	585394.RHOM_02915	0.0	1103.0	COG0664@1|root,COG0664@2|Bacteria,1TSX5@1239|Firmicutes,24A8U@186801|Clostridia	186801|Clostridia	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
IHAFMDNN_00202	585394.RHOM_02910	7.2e-219	612.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
IHAFMDNN_00206	622312.ROSEINA2194_03457	3.04e-187	542.0	COG0419@1|root,COG0419@2|Bacteria,1TTBF@1239|Firmicutes,24CKY@186801|Clostridia	186801|Clostridia	L	DNA sulfur modification protein DndD	-	-	-	ko:K19171	-	-	-	-	ko00000,ko02048	-	-	-	AAA_23
IHAFMDNN_00207	1235790.C805_02970	1.01e-77	236.0	2E30B@1|root,32SUY@2|Bacteria,1UPTA@1239|Firmicutes,24T23@186801|Clostridia,25YY1@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00208	622312.ROSEINA2194_03455	0.0	1513.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,249YY@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_4
IHAFMDNN_00209	622312.ROSEINA2194_03454	1.52e-177	499.0	COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,24CB1@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
IHAFMDNN_00210	622312.ROSEINA2194_03453	2.91e-51	163.0	COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,24N00@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
IHAFMDNN_00211	585394.RHOM_05385	4.41e-151	435.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
IHAFMDNN_00212	585394.RHOM_05390	9.64e-179	510.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
IHAFMDNN_00213	585394.RHOM_05395	6.32e-178	499.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
IHAFMDNN_00214	585394.RHOM_11155	2.89e-227	627.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
IHAFMDNN_00215	397290.C810_01607	1.68e-239	685.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZ3@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
IHAFMDNN_00216	585394.RHOM_11145	1.11e-142	412.0	COG1879@1|root,COG1879@2|Bacteria,1UYPR@1239|Firmicutes,248AW@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K17213	ko02010,map02010	M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
IHAFMDNN_00217	397291.C804_05620	1.36e-76	233.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,27MP7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
IHAFMDNN_00218	585394.RHOM_05465	1.12e-253	702.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
IHAFMDNN_00219	622312.ROSEINA2194_01033	3.2e-53	167.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
IHAFMDNN_00220	622312.ROSEINA2194_01034	1.85e-85	253.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
IHAFMDNN_00221	622312.ROSEINA2194_01035	2.38e-36	124.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
IHAFMDNN_00222	585394.RHOM_05485	0.0	1020.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
IHAFMDNN_00223	622312.ROSEINA2194_01037	1e-47	155.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
IHAFMDNN_00224	585394.RHOM_05490	4.65e-55	178.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
IHAFMDNN_00225	622312.ROSEINA2194_01039	3.29e-124	357.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
IHAFMDNN_00226	622312.ROSEINA2194_01040	4.03e-280	767.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia	186801|Clostridia	O	peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
IHAFMDNN_00227	1235793.C809_01302	1.97e-125	380.0	2BP58@1|root,32HW3@2|Bacteria,1V8J8@1239|Firmicutes,24HB1@186801|Clostridia,27PAY@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
IHAFMDNN_00228	622312.ROSEINA2194_02923	9.12e-69	212.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
IHAFMDNN_00230	622312.ROSEINA2194_02236	1.79e-287	786.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
IHAFMDNN_00231	632245.CLP_0713	5.29e-134	386.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,36E3F@31979|Clostridiaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
IHAFMDNN_00233	1235802.C823_05092	1.44e-124	394.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25WEQ@186806|Eubacteriaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
IHAFMDNN_00234	1235802.C823_05093	6.62e-62	197.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,25X89@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
IHAFMDNN_00235	537007.BLAHAN_06528	4.37e-75	234.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
IHAFMDNN_00236	622312.ROSEINA2194_02467	9.5e-142	402.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IHAFMDNN_00237	585394.RHOM_03635	2.18e-238	681.0	COG2200@1|root,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
IHAFMDNN_00238	622312.ROSEINA2194_00344	3.32e-130	374.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
IHAFMDNN_00239	1007096.BAGW01000014_gene1156	1.51e-77	253.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
IHAFMDNN_00241	1121344.JHZO01000003_gene939	1.93e-59	190.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,3WM16@541000|Ruminococcaceae	186801|Clostridia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
IHAFMDNN_00242	411489.CLOL250_02693	4.38e-108	342.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Big_2,Big_5,CBM_48,Flg_new,Gram_pos_anchor,PUD,SLH
IHAFMDNN_00243	585394.RHOM_11010	7.74e-244	678.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IHAFMDNN_00244	585394.RHOM_11015	9.49e-147	415.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_00245	585394.RHOM_11020	2.39e-172	499.0	COG0845@1|root,COG0845@2|Bacteria,1V4XJ@1239|Firmicutes,25CIU@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
IHAFMDNN_00246	585394.RHOM_11025	1.71e-41	145.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
IHAFMDNN_00247	622312.ROSEINA2194_04095	2.4e-77	239.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
IHAFMDNN_00248	585394.RHOM_06185	1.76e-154	439.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
IHAFMDNN_00251	585394.RHOM_15800	1.64e-52	170.0	2EHCT@1|root,33B4M@2|Bacteria,1UPNG@1239|Firmicutes	1239|Firmicutes	S	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
IHAFMDNN_00252	585394.RHOM_15795	1.89e-92	286.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
IHAFMDNN_00253	585394.RHOM_15790	9.1e-196	554.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
IHAFMDNN_00254	585394.RHOM_15785	4.06e-79	245.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
IHAFMDNN_00255	622312.ROSEINA2194_00761	9.66e-94	295.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
IHAFMDNN_00256	397287.C807_03605	8.06e-11	58.2	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
IHAFMDNN_00257	585394.RHOM_15770	2.03e-104	328.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00258	622312.ROSEINA2194_00764	2.27e-67	217.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
IHAFMDNN_00259	1235793.C809_01839	2.26e-54	171.0	COG3695@1|root,COG3695@2|Bacteria,1UIU9@1239|Firmicutes,25ES2@186801|Clostridia,27UK4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
IHAFMDNN_00260	622312.ROSEINA2194_00788	6.32e-83	247.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
IHAFMDNN_00261	471875.RUMLAC_00843	4.72e-63	199.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3WK3Z@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
IHAFMDNN_00262	585394.RHOM_13905	0.0	1194.0	COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
IHAFMDNN_00263	1226325.HMPREF1548_05938	2.85e-65	200.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,36KQ7@31979|Clostridiaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
IHAFMDNN_00265	180332.JTGN01000006_gene3154	3.62e-173	496.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
IHAFMDNN_00268	1121115.AXVN01000018_gene50	5.68e-113	327.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
IHAFMDNN_00269	397291.C804_02843	1.4e-124	356.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,27K57@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
IHAFMDNN_00270	1121115.AXVN01000018_gene47	3.74e-208	583.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
IHAFMDNN_00271	1121115.AXVN01000018_gene46	0.0	1168.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
IHAFMDNN_00272	397288.C806_01988	7.85e-98	288.0	COG0705@1|root,COG0705@2|Bacteria,1V1C3@1239|Firmicutes,24GPR@186801|Clostridia,27KQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
IHAFMDNN_00273	585394.RHOM_12010	1.91e-236	651.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
IHAFMDNN_00274	585394.RHOM_12005	4.97e-221	610.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
IHAFMDNN_00275	585394.RHOM_12000	2.01e-257	713.0	COG0836@1|root,COG1917@1|root,COG0836@2|Bacteria,COG1917@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia	186801|Clostridia	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
IHAFMDNN_00276	585394.RHOM_11965	5.86e-61	189.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
IHAFMDNN_00279	585394.RHOM_11955	3.48e-156	445.0	COG2333@1|root,COG2333@2|Bacteria,1UEY5@1239|Firmicutes,24E8K@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
IHAFMDNN_00280	483218.BACPEC_02375	9.72e-209	585.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,2682F@186813|unclassified Clostridiales	186801|Clostridia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
IHAFMDNN_00281	622312.ROSEINA2194_04390	0.0	1399.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_00283	796942.HMPREF9623_01507	1.68e-159	466.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_00284	796942.HMPREF9623_01506	2.35e-118	343.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia	186801|Clostridia	T	response regulator receiver	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00286	622312.ROSEINA2194_04316	1.28e-80	241.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
IHAFMDNN_00287	1469948.JPNB01000002_gene3764	7.26e-21	93.2	COG1835@1|root,COG1835@2|Bacteria,1UY2A@1239|Firmicutes,24D38@186801|Clostridia,36IC7@31979|Clostridiaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IHAFMDNN_00288	1235800.C819_01132	1.38e-38	139.0	COG1835@1|root,COG1835@2|Bacteria,1UY2A@1239|Firmicutes,24D38@186801|Clostridia,27IZK@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IHAFMDNN_00289	428125.CLOLEP_03130	6.55e-29	108.0	COG1476@1|root,COG1476@2|Bacteria,1V72D@1239|Firmicutes,24GUG@186801|Clostridia,3WKCB@541000|Ruminococcaceae	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,MazE_antitoxin
IHAFMDNN_00290	556261.HMPREF0240_00813	8.36e-123	363.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,248BZ@186801|Clostridia,36E93@31979|Clostridiaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_00291	1469948.JPNB01000002_gene3622	9.18e-203	575.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
IHAFMDNN_00292	1469948.JPNB01000002_gene3616	0.0	1007.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,36FQM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_00293	658086.HMPREF0994_04316	1.46e-83	261.0	COG2207@1|root,COG2207@2|Bacteria,1UGXT@1239|Firmicutes,24EUQ@186801|Clostridia,27NK5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
IHAFMDNN_00294	1226325.HMPREF1548_02854	7.74e-213	595.0	COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,248Z1@186801|Clostridia,36F9Z@31979|Clostridiaceae	186801|Clostridia	S	Glucuronyl hydrolase	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
IHAFMDNN_00295	585394.RHOM_04080	1.72e-88	283.0	COG3387@1|root,COG3387@2|Bacteria,1UI0N@1239|Firmicutes,25DI4@186801|Clostridia	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_N
IHAFMDNN_00296	411469.EUBHAL_03045	4.2e-68	209.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
IHAFMDNN_00297	457421.CBFG_05476	2.62e-59	191.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,269B4@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
IHAFMDNN_00298	585394.RHOM_14370	2.55e-133	383.0	COG2357@1|root,COG2357@2|Bacteria	2|Bacteria	S	guanosine tetraphosphate metabolic process	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
IHAFMDNN_00299	622312.ROSEINA2194_01965	2.94e-251	694.0	COG4284@1|root,COG4284@2|Bacteria,1TQUD@1239|Firmicutes,24A8D@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
IHAFMDNN_00300	585394.RHOM_14380	1.04e-173	488.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IHAFMDNN_00301	742765.HMPREF9457_00411	5.49e-147	466.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27WC0@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
IHAFMDNN_00302	411461.DORFOR_00617	8.69e-56	183.0	COG0834@1|root,COG0834@2|Bacteria,1VTCR@1239|Firmicutes,24YIS@186801|Clostridia,27WVQ@189330|Dorea	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
IHAFMDNN_00303	1235790.C805_00476	4.9e-156	454.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,25VSZ@186806|Eubacteriaceae	186801|Clostridia	GM	CoA-binding domain	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
IHAFMDNN_00304	742735.HMPREF9467_03385	2.48e-72	240.0	COG3950@1|root,COG3950@2|Bacteria,1V5R6@1239|Firmicutes,24DVP@186801|Clostridia,222SD@1506553|Lachnoclostridium	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
IHAFMDNN_00305	526224.Bmur_1782	1.11e-27	110.0	2DPMA@1|root,332MS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00306	1121289.JHVL01000007_gene2812	1.98e-108	317.0	COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,24874@186801|Clostridia,36VHP@31979|Clostridiaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf,Epimerase
IHAFMDNN_00307	1235798.C817_00116	2.88e-97	295.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	wbpV	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
IHAFMDNN_00308	877421.AUJT01000004_gene2306	1.09e-88	269.0	COG1215@1|root,COG1215@2|Bacteria,1V4KD@1239|Firmicutes,24HZQ@186801|Clostridia,27KGG@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_00309	632335.Calkr_2278	5.34e-91	287.0	COG0297@1|root,COG0297@2|Bacteria,1TQWW@1239|Firmicutes,25FJB@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
IHAFMDNN_00310	1235802.C823_01905	5.17e-189	536.0	COG1479@1|root,COG1479@2|Bacteria,1V3XN@1239|Firmicutes,24PZA@186801|Clostridia,25YYZ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
IHAFMDNN_00311	585394.RHOM_08770	8.15e-245	684.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
IHAFMDNN_00312	585394.RHOM_08775	2.47e-183	538.0	28HJQ@1|root,2Z7UU@2|Bacteria,1UPMJ@1239|Firmicutes,24BW1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
IHAFMDNN_00313	411469.EUBHAL_02519	1.89e-186	559.0	28N1Z@1|root,2ZB7X@2|Bacteria,1UZID@1239|Firmicutes,24F7M@186801|Clostridia,25Y86@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00314	585394.RHOM_08780	1.37e-123	362.0	28H6W@1|root,2ZA4C@2|Bacteria,1UXGN@1239|Firmicutes,24AZN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00315	585394.RHOM_08785	8.51e-78	253.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
IHAFMDNN_00316	622312.ROSEINA2194_00064	5.19e-61	193.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
IHAFMDNN_00317	585394.RHOM_09775	7.46e-72	216.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
IHAFMDNN_00319	411474.COPEUT_00135	8.9e-86	268.0	COG1670@1|root,COG3393@1|root,COG1670@2|Bacteria,COG3393@2|Bacteria,1V1G4@1239|Firmicutes,24G4Y@186801|Clostridia	186801|Clostridia	J	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
IHAFMDNN_00320	585394.RHOM_05295	5.36e-271	744.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IHAFMDNN_00321	1280694.AUJQ01000005_gene1348	1.93e-66	229.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3NGP7@46205|Pseudobutyrivibrio	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,HisKA_7TM
IHAFMDNN_00322	140626.JHWB01000019_gene917	3.12e-24	103.0	COG2214@1|root,COG2214@2|Bacteria,1V4YZ@1239|Firmicutes,24U0J@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00323	457412.RSAG_01565	9.84e-131	372.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3WH3X@541000|Ruminococcaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
IHAFMDNN_00324	1173026.Glo7428_1322	7.89e-51	176.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
IHAFMDNN_00325	585394.RHOM_05520	9.48e-114	343.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia	186801|Clostridia	D	Sporulation integral membrane protein YtvI	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IHAFMDNN_00326	622312.ROSEINA2194_03512	4.54e-238	662.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
IHAFMDNN_00327	622312.ROSEINA2194_03511	0.0	885.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
IHAFMDNN_00328	622312.ROSEINA2194_03510	4.13e-215	599.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IHAFMDNN_00329	622312.ROSEINA2194_03509	4.97e-207	575.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IHAFMDNN_00330	742765.HMPREF9457_00204	1.49e-119	350.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,27VZT@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_00331	1232447.BAHW02000038_gene2598	3.87e-29	115.0	COG0791@1|root,COG4886@1|root,COG0791@2|Bacteria,COG4886@2|Bacteria,1VI5Y@1239|Firmicutes,25FC1@186801|Clostridia	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,NLPC_P60
IHAFMDNN_00332	622312.ROSEINA2194_04062	4.74e-157	449.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IHAFMDNN_00333	457412.RSAG_02477	4.64e-272	754.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
IHAFMDNN_00335	585394.RHOM_14345	7.9e-247	679.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
IHAFMDNN_00336	622312.ROSEINA2194_00449	7.95e-317	870.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
IHAFMDNN_00337	585394.RHOM_14335	1.71e-47	155.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
IHAFMDNN_00338	622312.ROSEINA2194_04436	9.42e-161	452.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00339	1469948.JPNB01000001_gene964	2.93e-249	691.0	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,36HI8@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
IHAFMDNN_00340	1469948.JPNB01000002_gene3625	0.0	1008.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,36FIY@31979|Clostridiaceae	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
IHAFMDNN_00341	585394.RHOM_04085	0.0	1028.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_00342	1469948.JPNB01000002_gene3623	3.12e-153	448.0	COG3507@1|root,COG5492@1|root,COG3507@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Glyco_hydro_43,Laminin_G_3
IHAFMDNN_00343	1469948.JPNB01000002_gene3621	1.24e-259	724.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia,36E91@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
IHAFMDNN_00344	622312.ROSEINA2194_03722	1.9e-61	188.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
IHAFMDNN_00345	622312.ROSEINA2194_03721	1.19e-62	192.0	COG2868@1|root,COG2868@2|Bacteria	2|Bacteria	J	Cysteine protease Prp	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
IHAFMDNN_00346	585394.RHOM_07535	6.63e-63	192.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
IHAFMDNN_00347	411463.EUBVEN_00827	1.85e-152	433.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
IHAFMDNN_00348	585394.RHOM_07470	1.71e-159	462.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
IHAFMDNN_00349	585394.RHOM_07465	2.31e-123	357.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
IHAFMDNN_00350	585394.RHOM_07460	0.0	1066.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
IHAFMDNN_00351	1280688.AUJB01000016_gene1536	3.32e-20	92.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3NHV9@46205|Pseudobutyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
IHAFMDNN_00352	411461.DORFOR_02251	8.94e-182	509.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,27W8Q@189330|Dorea	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00353	585394.RHOM_10150	0.0	1033.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IHAFMDNN_00354	411468.CLOSCI_03722	1.33e-185	526.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,21Y5G@1506553|Lachnoclostridium	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
IHAFMDNN_00355	622312.ROSEINA2194_02760	6.47e-137	395.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
IHAFMDNN_00357	1280680.AUJU01000016_gene3966	1.05e-102	317.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,4BYMU@830|Butyrivibrio	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
IHAFMDNN_00358	180332.JTGN01000007_gene3643	3.76e-57	179.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
IHAFMDNN_00359	585394.RHOM_08485	2.73e-167	474.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
IHAFMDNN_00360	622312.ROSEINA2194_00453	6.57e-154	440.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
IHAFMDNN_00361	585394.RHOM_08475	1.16e-171	484.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
IHAFMDNN_00362	585394.RHOM_08470	5.9e-165	476.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UBS0@1239|Firmicutes,25B2D@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
IHAFMDNN_00363	585394.RHOM_08465	3.3e-48	154.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
IHAFMDNN_00364	585394.RHOM_08460	0.0	1293.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
IHAFMDNN_00365	1235790.C805_03587	2.17e-117	356.0	COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,24GB5@186801|Clostridia,25WC7@186806|Eubacteriaceae	186801|Clostridia	N	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	CAP,SLH
IHAFMDNN_00366	585394.RHOM_14040	1.35e-42	140.0	2C5I7@1|root,330HE@2|Bacteria,1VJU8@1239|Firmicutes,24SCX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
IHAFMDNN_00369	622312.ROSEINA2194_02852	2.71e-176	498.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
IHAFMDNN_00370	585394.RHOM_14045	9.97e-77	231.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
IHAFMDNN_00372	622312.ROSEINA2194_00805	1.28e-166	473.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
IHAFMDNN_00373	585394.RHOM_14055	3.99e-312	859.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
IHAFMDNN_00374	483218.BACPEC_02584	7.75e-57	178.0	COG3668@1|root,COG3668@2|Bacteria,1V9NW@1239|Firmicutes,24KYQ@186801|Clostridia,2697W@186813|unclassified Clostridiales	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
IHAFMDNN_00375	585394.RHOM_09975	7.81e-89	268.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
IHAFMDNN_00376	585394.RHOM_09980	3.28e-128	367.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
IHAFMDNN_00377	585394.RHOM_09985	2.14e-162	460.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
IHAFMDNN_00378	585394.RHOM_09990	2.93e-284	802.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
IHAFMDNN_00379	622312.ROSEINA2194_03525	6.45e-125	361.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia	186801|Clostridia	T	Phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
IHAFMDNN_00380	622312.ROSEINA2194_03526	2.31e-193	541.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
IHAFMDNN_00381	585394.RHOM_03640	4.69e-267	751.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IHAFMDNN_00382	666681.M301_0409	3.2e-21	106.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria,2KKKT@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
IHAFMDNN_00385	1410618.JNKI01000001_gene1318	1.47e-30	124.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,4H30J@909932|Negativicutes	909932|Negativicutes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
IHAFMDNN_00386	585394.RHOM_03645	1.58e-73	223.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
IHAFMDNN_00387	622312.ROSEINA2194_02462	3.48e-134	385.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
IHAFMDNN_00388	585394.RHOM_05365	3.28e-159	450.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
IHAFMDNN_00389	585394.RHOM_05355	0.0	1160.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
IHAFMDNN_00390	585394.RHOM_05350	2.6e-149	424.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
IHAFMDNN_00391	585394.RHOM_05340	8.91e-179	501.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
IHAFMDNN_00392	33035.JPJF01000032_gene2180	0.0	952.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
IHAFMDNN_00393	33035.JPJF01000032_gene2181	9.02e-165	465.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
IHAFMDNN_00394	33035.JPJF01000032_gene2182	2.43e-188	526.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
IHAFMDNN_00395	33035.JPJF01000032_gene2183	3.93e-269	744.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	araN	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
IHAFMDNN_00396	33035.JPJF01000032_gene2184	0.0	967.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
IHAFMDNN_00397	742765.HMPREF9457_03255	7.21e-145	421.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
IHAFMDNN_00399	585394.RHOM_08515	3.83e-99	288.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
IHAFMDNN_00400	585394.RHOM_08510	1.18e-232	647.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
IHAFMDNN_00401	585394.RHOM_08505	1.74e-49	158.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
IHAFMDNN_00402	585394.RHOM_08500	1.52e-51	164.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
IHAFMDNN_00403	585394.RHOM_08495	0.0	1161.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
IHAFMDNN_00404	585394.RHOM_12410	1.42e-163	466.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00405	585394.RHOM_12405	9.81e-166	469.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
IHAFMDNN_00406	585394.RHOM_12400	3.51e-145	429.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
IHAFMDNN_00407	622312.ROSEINA2194_02611	4.67e-297	813.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IHAFMDNN_00408	585394.RHOM_12390	6.68e-52	164.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IHAFMDNN_00409	585394.RHOM_12385	2.05e-179	503.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
IHAFMDNN_00410	1226325.HMPREF1548_00432	3.79e-151	431.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
IHAFMDNN_00411	658086.HMPREF0994_04640	5.81e-189	529.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27MDB@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IHAFMDNN_00412	658086.HMPREF0994_04641	3.95e-151	435.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,27JBD@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IHAFMDNN_00413	658086.HMPREF0994_04642	9.88e-164	466.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27QSG@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
IHAFMDNN_00414	658086.HMPREF0994_04643	1.82e-297	823.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,27RMB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IHAFMDNN_00415	1235802.C823_03877	6.31e-28	110.0	COG2866@1|root,COG3409@1|root,COG2866@2|Bacteria,COG3409@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
IHAFMDNN_00416	411469.EUBHAL_02917	5.8e-144	415.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,25VJT@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
IHAFMDNN_00417	585394.RHOM_09385	1.2e-76	246.0	2DMDS@1|root,32QT4@2|Bacteria,1UINH@1239|Firmicutes,25EP3@186801|Clostridia	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
IHAFMDNN_00418	622312.ROSEINA2194_00480	1.98e-203	576.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
IHAFMDNN_00419	1414720.CBYM010000014_gene2732	1.56e-315	900.0	COG3250@1|root,COG3250@2|Bacteria,1TU92@1239|Firmicutes,248WD@186801|Clostridia,36FQK@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_00421	1121335.Clst_1083	7e-118	348.0	COG1175@1|root,COG1175@2|Bacteria,1U73Q@1239|Firmicutes,24AFP@186801|Clostridia,3WHI4@541000|Ruminococcaceae	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
IHAFMDNN_00422	1121335.Clst_1084	1.88e-130	381.0	COG0395@1|root,COG0395@2|Bacteria,1UYH5@1239|Firmicutes,24AMA@186801|Clostridia,3WH39@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IHAFMDNN_00423	1094508.Tsac_1165	8.57e-130	392.0	COG1653@1|root,COG1653@2|Bacteria,1TXES@1239|Firmicutes,25JZ6@186801|Clostridia,42INH@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	-
IHAFMDNN_00424	357809.Cphy_3376	1.45e-41	147.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,21YZW@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
IHAFMDNN_00425	1449050.JNLE01000003_gene2847	1.66e-101	309.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia,36HMC@31979|Clostridiaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_00426	397291.C804_03195	1.02e-224	623.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,27JZU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
IHAFMDNN_00427	585394.RHOM_02535	0.0	1315.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
IHAFMDNN_00429	397287.C807_03073	1.23e-12	62.4	2EIY3@1|root,33CP9@2|Bacteria,1VN11@1239|Firmicutes,24W71@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00430	411483.FAEPRAA2165_02657	8.46e-49	162.0	COG3597@1|root,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,249YT@186801|Clostridia,3WKSA@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
IHAFMDNN_00431	556261.HMPREF0240_04096	1.23e-16	75.1	COG5566@1|root,COG5566@2|Bacteria,1VK7Y@1239|Firmicutes,24SS6@186801|Clostridia,36MMH@31979|Clostridiaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
IHAFMDNN_00434	1095750.HMPREF9970_1659	1.98e-31	137.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pkinase
IHAFMDNN_00435	411462.DORLON_02611	0.0	989.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
IHAFMDNN_00436	411462.DORLON_02610	3.47e-153	432.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia	186801|Clostridia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
IHAFMDNN_00437	411462.DORLON_02609	3.79e-297	816.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea	186801|Clostridia	S	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
IHAFMDNN_00438	411462.DORLON_02608	2.74e-275	756.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
IHAFMDNN_00439	411462.DORLON_02607	7.65e-65	199.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,27VRH@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
IHAFMDNN_00440	877420.ATVW01000072_gene839	5.42e-14	74.7	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,27MRG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00441	515620.EUBELI_00788	6.49e-35	129.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,25WQJ@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
IHAFMDNN_00442	585394.RHOM_03050	9.9e-203	567.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IHAFMDNN_00443	585394.RHOM_03055	9.07e-68	211.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia	186801|Clostridia	E	Abc transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
IHAFMDNN_00444	622312.ROSEINA2194_00694	2.31e-75	230.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia	186801|Clostridia	E	Abc transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
IHAFMDNN_00445	622312.ROSEINA2194_00695	1.35e-150	425.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia	186801|Clostridia	E	Abc transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
IHAFMDNN_00446	585394.RHOM_03065	2.73e-122	351.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IHAFMDNN_00447	585394.RHOM_03075	7.95e-193	544.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
IHAFMDNN_00448	397287.C807_00819	4.68e-107	313.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,27KNA@186928|unclassified Lachnospiraceae	186801|Clostridia	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IHAFMDNN_00449	610130.Closa_2435	1.3e-177	511.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,21XK8@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IHAFMDNN_00450	622312.ROSEINA2194_03952	1.19e-187	526.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III (delta' subunit)	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
IHAFMDNN_00451	585394.RHOM_05630	4.28e-189	568.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
IHAFMDNN_00452	585394.RHOM_05625	2.47e-162	462.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
IHAFMDNN_00453	585394.RHOM_05620	1.5e-272	754.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_00454	585394.RHOM_05615	1.77e-50	164.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00455	585394.RHOM_05615	2.27e-64	202.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00456	1410632.JHWW01000002_gene2339	5e-48	169.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,27J3F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IHAFMDNN_00457	1235793.C809_01814	1.87e-180	522.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,27J3F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IHAFMDNN_00458	622312.ROSEINA2194_00851	0.0	1589.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_00459	622312.ROSEINA2194_00853	1.04e-127	364.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
IHAFMDNN_00460	622312.ROSEINA2194_03392	3.08e-57	184.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00463	397288.C806_04570	2.21e-05	53.5	COG1345@1|root,COG1345@2|Bacteria,1VU42@1239|Firmicutes,24Y6R@186801|Clostridia,27KHZ@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	FliD_C
IHAFMDNN_00464	585394.RHOM_06765	2.9e-58	182.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
IHAFMDNN_00465	585394.RHOM_06760	7.49e-130	372.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_00466	585394.RHOM_06755	1.56e-61	202.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00467	622312.ROSEINA2194_00367	0.0	940.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
IHAFMDNN_00468	585394.RHOM_05275	0.0	908.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
IHAFMDNN_00469	585394.RHOM_05270	1.21e-226	633.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
IHAFMDNN_00470	622312.ROSEINA2194_02750	1.18e-43	146.0	2FBHF@1|root,343NR@2|Bacteria,1W0XC@1239|Firmicutes,253BM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00471	1235790.C805_00453	1.68e-52	200.0	COG5279@1|root,COG5279@2|Bacteria	2|Bacteria	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Flg_new
IHAFMDNN_00472	585394.RHOM_06145	1.3e-139	401.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
IHAFMDNN_00473	585394.RHOM_06225	0.0	1073.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
IHAFMDNN_00474	622312.ROSEINA2194_02815	0.0	960.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IHAFMDNN_00475	585394.RHOM_06235	2.21e-255	701.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
IHAFMDNN_00476	585394.RHOM_06240	7.92e-253	696.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
IHAFMDNN_00477	585394.RHOM_09870	5.07e-39	129.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
IHAFMDNN_00478	622312.ROSEINA2194_00046	1.45e-94	278.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia	186801|Clostridia	S	acr, cog1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
IHAFMDNN_00479	585394.RHOM_09880	2.45e-254	701.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
IHAFMDNN_00480	622312.ROSEINA2194_00044	3.56e-134	399.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
IHAFMDNN_00481	585394.RHOM_09910	8.22e-269	737.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
IHAFMDNN_00482	622312.ROSEINA2194_00040	2.45e-154	435.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
IHAFMDNN_00483	1536773.R70331_07050	1.92e-122	385.0	COG2207@1|root,COG3664@1|root,COG2207@2|Bacteria,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,4HE9D@91061|Bacilli,26U5K@186822|Paenibacillaceae	91061|Bacilli	K	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	AraC_binding,Cupin_2,Glyco_hydro_39,HTH_18
IHAFMDNN_00484	1408312.JNJS01000002_gene213	2.05e-99	294.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,3NH8G@46205|Pseudobutyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
IHAFMDNN_00485	585394.RHOM_06060	2.8e-190	533.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
IHAFMDNN_00486	1235802.C823_03873	8.76e-257	720.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia,25V36@186806|Eubacteriaceae	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
IHAFMDNN_00487	33035.JPJF01000009_gene1487	2.19e-253	710.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IHAFMDNN_00488	1196322.A370_01851	6.25e-159	452.0	COG2730@1|root,COG2730@2|Bacteria,1TT32@1239|Firmicutes,24DD1@186801|Clostridia,36EG6@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00489	573061.Clocel_3339	9.11e-99	299.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,25BJI@186801|Clostridia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
IHAFMDNN_00490	622312.ROSEINA2194_02877	1.33e-85	271.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IHAFMDNN_00491	585394.RHOM_11490	5.18e-159	461.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia	186801|Clostridia	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
IHAFMDNN_00493	585394.RHOM_03980	8.41e-38	139.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
IHAFMDNN_00494	622312.ROSEINA2194_02883	1.14e-59	185.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
IHAFMDNN_00495	585394.RHOM_16890	2.79e-127	367.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
IHAFMDNN_00496	622312.ROSEINA2194_03228	0.0	1118.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
IHAFMDNN_00497	622312.ROSEINA2194_03229	5.01e-273	753.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
IHAFMDNN_00498	622312.ROSEINA2194_03230	1.05e-118	342.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
IHAFMDNN_00499	585394.RHOM_16915	1.17e-217	611.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
IHAFMDNN_00500	622312.ROSEINA2194_01364	2.68e-111	328.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,25B6T@186801|Clostridia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IHAFMDNN_00501	585394.RHOM_09350	8.03e-301	826.0	COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia	186801|Clostridia	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4
IHAFMDNN_00502	483218.BACPEC_02951	9.77e-127	376.0	COG2199@1|root,COG2199@2|Bacteria,1VBH6@1239|Firmicutes,24P8P@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IHAFMDNN_00503	483218.BACPEC_02952	1.9e-84	264.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,26BFC@186813|unclassified Clostridiales	186801|Clostridia	S	Serine hydrolase (FSH1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
IHAFMDNN_00505	622312.ROSEINA2194_02414	1.14e-121	352.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
IHAFMDNN_00506	585394.RHOM_01465	8.64e-151	427.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
IHAFMDNN_00507	1415775.U729_2947	1.89e-36	129.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,24R64@186801|Clostridia,36NH8@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
IHAFMDNN_00508	1235798.C817_02114	1.96e-100	309.0	COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,25AZB@186801|Clostridia	186801|Clostridia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
IHAFMDNN_00509	1235798.C817_02113	2.02e-17	74.3	2EJDK@1|root,33D4M@2|Bacteria,1VPVH@1239|Firmicutes,24VVZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
IHAFMDNN_00510	476272.RUMHYD_01730	7.48e-58	189.0	2DPEI@1|root,331RX@2|Bacteria,1VIYX@1239|Firmicutes,24REE@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5067)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
IHAFMDNN_00511	585394.RHOM_01470	3.97e-97	282.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
IHAFMDNN_00512	585394.RHOM_01475	3.52e-83	246.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
IHAFMDNN_00513	585394.RHOM_16670	4.05e-104	305.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia	186801|Clostridia	S	membrane protein required for spore maturation	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
IHAFMDNN_00514	622312.ROSEINA2194_04339	7.24e-231	654.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
IHAFMDNN_00515	585394.RHOM_16660	2.33e-84	253.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia	186801|Clostridia	S	PFAM nucleoside recognition domain protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
IHAFMDNN_00517	483218.BACPEC_02910	1.51e-148	446.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,268D0@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
IHAFMDNN_00518	585394.RHOM_16655	1.52e-156	441.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
IHAFMDNN_00519	1256908.HMPREF0373_02491	6.34e-31	112.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,25WX5@186806|Eubacteriaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
IHAFMDNN_00520	1123075.AUDP01000021_gene1398	1.13e-29	108.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,3WJCK@541000|Ruminococcaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
IHAFMDNN_00521	622312.ROSEINA2194_04343	1.88e-33	116.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
IHAFMDNN_00522	585394.RHOM_03450	7.15e-43	140.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IHAFMDNN_00523	1226325.HMPREF1548_05939	6.25e-36	122.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,36MP8@31979|Clostridiaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
IHAFMDNN_00524	658086.HMPREF0994_06533	0.0	962.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,27IHI@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_00525	1274374.CBLK010000070_gene1204	1.63e-200	604.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HB2V@91061|Bacilli,26SFU@186822|Paenibacillaceae	1239|Firmicutes	G	Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
IHAFMDNN_00526	622312.ROSEINA2194_01770	1.55e-65	201.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
IHAFMDNN_00527	585394.RHOM_03480	3.73e-40	133.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24R22@186801|Clostridia	186801|Clostridia	P	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
IHAFMDNN_00528	622312.ROSEINA2194_01772	0.0	972.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
IHAFMDNN_00529	411902.CLOBOL_05591	7.11e-34	120.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,2218J@1506553|Lachnoclostridium	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00530	585394.RHOM_10175	0.0	1105.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia	186801|Clostridia	P	heavy metal translocating P-type ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
IHAFMDNN_00531	622312.ROSEINA2194_00049	1.1e-220	612.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
IHAFMDNN_00532	585394.RHOM_09845	1.51e-41	137.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
IHAFMDNN_00533	622312.ROSEINA2194_00051	1.2e-129	372.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
IHAFMDNN_00534	585394.RHOM_09830	0.0	1574.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
IHAFMDNN_00535	411474.COPEUT_01236	3.11e-299	894.0	COG4124@1|root,COG4733@1|root,COG4124@2|Bacteria,COG4733@2|Bacteria,1TSXQ@1239|Firmicutes,24CRT@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM27,CBM_11,CW_binding_1,Glyco_hydro_26,Gram_pos_anchor,SLH
IHAFMDNN_00536	641107.CDLVIII_5765	5.84e-101	300.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
IHAFMDNN_00537	641107.CDLVIII_5764	9.19e-81	248.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,36FAP@31979|Clostridiaceae	186801|Clostridia	E	acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
IHAFMDNN_00538	794846.AJQU01000046_gene4554	2.38e-74	232.0	COG0834@1|root,COG0834@2|Bacteria,1MXME@1224|Proteobacteria,2TT4J@28211|Alphaproteobacteria,4BBEK@82115|Rhizobiaceae	28211|Alphaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
IHAFMDNN_00539	585394.RHOM_10170	2.43e-147	424.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
IHAFMDNN_00540	483218.BACPEC_02957	1.51e-68	227.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26BFA@186813|unclassified Clostridiales	186801|Clostridia	NT	Single cache domain 3	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_3_3
IHAFMDNN_00541	1235800.C819_02568	1.14e-59	208.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27K3V@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,dCache_1
IHAFMDNN_00542	622312.ROSEINA2194_01368	1.55e-78	238.0	COG1051@1|root,COG1051@2|Bacteria,1UUZ0@1239|Firmicutes,24NDR@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IHAFMDNN_00543	585394.RHOM_09310	3.39e-98	286.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
IHAFMDNN_00544	585394.RHOM_09305	1.01e-177	498.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IHAFMDNN_00545	585394.RHOM_09300	4.49e-246	684.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00546	622312.ROSEINA2194_03328	2.45e-294	817.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
IHAFMDNN_00547	622312.ROSEINA2194_03329	1.33e-258	711.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
IHAFMDNN_00548	1408324.JNJK01000005_gene1128	1.65e-192	547.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,27JK2@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IHAFMDNN_00549	585394.RHOM_11030	7.5e-129	370.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
IHAFMDNN_00550	622312.ROSEINA2194_02729	1.42e-170	482.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
IHAFMDNN_00551	622312.ROSEINA2194_02730	8.71e-159	449.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
IHAFMDNN_00552	622312.ROSEINA2194_02731	1.36e-136	392.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
IHAFMDNN_00553	585394.RHOM_08675	1.66e-182	516.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
IHAFMDNN_00554	585394.RHOM_08680	1.6e-109	328.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00555	622312.ROSEINA2194_02735	2.08e-285	788.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
IHAFMDNN_00556	1120746.CCNL01000008_gene565	1.39e-96	289.0	COG2243@1|root,COG2243@2|Bacteria	2|Bacteria	H	precorrin-2 c20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151,4.99.1.3	ko:K02190,ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05807,R05808	RC00003,RC01012,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
IHAFMDNN_00557	585394.RHOM_08970	4.02e-39	131.0	COG2158@1|root,COG2158@2|Bacteria	2|Bacteria	S	Cysteine-rich small domain	cbiA	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
IHAFMDNN_00559	622312.ROSEINA2194_00478	1.79e-62	204.0	COG3773@1|root,COG3773@2|Bacteria,1VHG1@1239|Firmicutes,24SYE@186801|Clostridia	186801|Clostridia	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
IHAFMDNN_00560	1163671.JAGI01000002_gene2184	9.47e-55	187.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,36DIN@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
IHAFMDNN_00561	585394.RHOM_05970	4.04e-210	600.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
IHAFMDNN_00562	397290.C810_02248	5.99e-21	84.0	29VDD@1|root,325Y2@2|Bacteria,1UHHD@1239|Firmicutes,25JIV@186801|Clostridia,27SCF@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00563	397290.C810_02249	1.73e-35	122.0	COG5577@1|root,COG5577@2|Bacteria,1TU9X@1239|Firmicutes,25IH5@186801|Clostridia,27S9B@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F
IHAFMDNN_00564	585394.RHOM_10030	2.24e-219	623.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IHAFMDNN_00565	585394.RHOM_10035	2.14e-65	201.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IHAFMDNN_00566	585394.RHOM_10045	5.44e-200	556.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
IHAFMDNN_00567	585394.RHOM_10050	8.98e-47	153.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
IHAFMDNN_00568	622312.ROSEINA2194_03538	2.51e-119	344.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia	186801|Clostridia	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
IHAFMDNN_00569	585394.RHOM_04960	2.07e-137	394.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00570	585394.RHOM_03560	7.25e-107	322.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	araG_1	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
IHAFMDNN_00571	585394.RHOM_03565	5.86e-220	610.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IHAFMDNN_00572	585394.RHOM_03570	1.05e-214	596.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
IHAFMDNN_00573	585394.RHOM_03580	1.43e-167	477.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
IHAFMDNN_00574	585394.RHOM_09640	1.16e-115	350.0	28JJA@1|root,2Z9CD@2|Bacteria,1TPY4@1239|Firmicutes,24DSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00575	585394.RHOM_05225	4.54e-118	347.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
IHAFMDNN_00576	585394.RHOM_05230	2.39e-160	473.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00577	397288.C806_03858	4.48e-19	82.8	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24TDP@186801|Clostridia,27QMZ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00581	622312.ROSEINA2194_03514	0.0	1296.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
IHAFMDNN_00582	1235790.C805_02517	9.1e-151	463.0	COG4188@1|root,COG4188@2|Bacteria,1UGK7@1239|Firmicutes,24CXP@186801|Clostridia	186801|Clostridia	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
IHAFMDNN_00583	585394.RHOM_13045	1.43e-275	775.0	COG1609@1|root,COG2199@1|root,COG1609@2|Bacteria,COG3706@2|Bacteria,1TSMK@1239|Firmicutes,24EJV@186801|Clostridia	186801|Clostridia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Peripla_BP_3
IHAFMDNN_00584	622312.ROSEINA2194_01540	5.61e-127	361.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
IHAFMDNN_00585	1123313.ATUT01000016_gene618	3.71e-27	116.0	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,3VQ6J@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IHAFMDNN_00586	585394.RHOM_04970	1.64e-219	610.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
IHAFMDNN_00587	585394.RHOM_04975	4.32e-76	235.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
IHAFMDNN_00588	622312.ROSEINA2194_01132	0.0	1130.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
IHAFMDNN_00590	622312.ROSEINA2194_01272	1.36e-117	336.0	COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24G9Y@186801|Clostridia	186801|Clostridia	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
IHAFMDNN_00591	622312.ROSEINA2194_01273	1.35e-238	656.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
IHAFMDNN_00592	397291.C804_05719	0.0	1129.0	COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,25EI6@186801|Clostridia,27IJC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
IHAFMDNN_00593	622312.ROSEINA2194_01276	6.74e-126	359.0	28HKG@1|root,2Z7VB@2|Bacteria,1TZFI@1239|Firmicutes,24BXG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00594	622312.ROSEINA2194_01277	5.51e-60	184.0	2BXEN@1|root,32R17@2|Bacteria,1V7Y8@1239|Firmicutes,24SE0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00595	622312.ROSEINA2194_01278	3.31e-145	420.0	COG0270@1|root,COG0270@2|Bacteria,1TR36@1239|Firmicutes,249XY@186801|Clostridia	1239|Firmicutes	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
IHAFMDNN_00596	1089548.KI783301_gene2722	4.05e-16	75.1	2EIAE@1|root,33C1U@2|Bacteria,1VQ73@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00597	500632.CLONEX_03904	1.23e-85	259.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IHAFMDNN_00598	622312.ROSEINA2194_04469	5.1e-201	566.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IHAFMDNN_00599	585394.RHOM_05120	1.44e-191	547.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
IHAFMDNN_00600	483218.BACPEC_02966	1.55e-111	333.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,26A1M@186813|unclassified Clostridiales	186801|Clostridia	O	DnaJ molecular chaperone homology domain	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
IHAFMDNN_00601	1160721.RBI_I01639	5.82e-75	234.0	COG0726@1|root,COG0726@2|Bacteria,1V8XF@1239|Firmicutes,24JZT@186801|Clostridia,3WIMA@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Polysacc_deac_1
IHAFMDNN_00602	411474.COPEUT_00455	1.58e-69	231.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
IHAFMDNN_00603	585394.RHOM_09650	3.28e-269	780.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
IHAFMDNN_00604	585394.RHOM_09645	0.0	927.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
IHAFMDNN_00605	585394.RHOM_03545	5.95e-213	608.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
IHAFMDNN_00606	1256908.HMPREF0373_00101	0.0	1419.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
IHAFMDNN_00607	1235793.C809_01831	7.87e-34	119.0	COG4818@1|root,COG4818@2|Bacteria,1UN6A@1239|Firmicutes,25GXJ@186801|Clostridia,27Q73@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00608	585394.RHOM_11175	1.71e-148	420.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	vanR3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00609	622312.ROSEINA2194_00443	1.27e-55	182.0	2DSNT@1|root,33GUR@2|Bacteria,1VNR5@1239|Firmicutes,24WQ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00610	622312.ROSEINA2194_01974	5.51e-171	487.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
IHAFMDNN_00611	585394.RHOM_03910	6.02e-83	261.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia	186801|Clostridia	G	COG1879 ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
IHAFMDNN_00612	622312.ROSEINA2194_01972	0.0	932.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
IHAFMDNN_00613	622312.ROSEINA2194_01971	3.24e-195	558.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
IHAFMDNN_00614	622312.ROSEINA2194_02179	4.38e-22	89.4	2E5D8@1|root,33058@2|Bacteria,1VERG@1239|Firmicutes,24S0M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
IHAFMDNN_00615	658086.HMPREF0994_04050	1.68e-116	358.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,27KFI@186928|unclassified Lachnospiraceae	186801|Clostridia	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
IHAFMDNN_00616	585394.RHOM_03840	3.86e-74	228.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
IHAFMDNN_00618	585394.RHOM_04185	7.55e-143	405.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
IHAFMDNN_00619	585394.RHOM_04190	3.15e-61	193.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
IHAFMDNN_00620	1410630.JNKP01000001_gene1787	3.1e-118	346.0	COG0726@1|root,COG0726@2|Bacteria,1U0B6@1239|Firmicutes,24895@186801|Clostridia,27M6G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
IHAFMDNN_00621	1235792.C808_04909	1.12e-53	171.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
IHAFMDNN_00622	585394.RHOM_11700	4.26e-131	392.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
IHAFMDNN_00623	585394.RHOM_11695	1.29e-220	617.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IHAFMDNN_00624	585394.RHOM_11690	6.69e-175	501.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
IHAFMDNN_00625	622312.ROSEINA2194_04229	5.68e-297	811.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
IHAFMDNN_00626	585394.RHOM_11680	1.52e-120	344.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
IHAFMDNN_00627	585394.RHOM_05185	0.0	954.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
IHAFMDNN_00629	585394.RHOM_05175	2.9e-172	481.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
IHAFMDNN_00630	585394.RHOM_05170	5.56e-270	741.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
IHAFMDNN_00631	585394.RHOM_05165	3.88e-209	580.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
IHAFMDNN_00632	1120746.CCNL01000008_gene554	9.86e-129	370.0	COG1010@1|root,COG1010@2|Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,6.3.5.10	ko:K02232,ko:K05934,ko:K05936,ko:K13541	ko00860,ko01100,map00860,map01100	M00122	R05180,R05181,R05225,R05809,R05810,R07772	RC00003,RC00010,RC01293,RC01294,RC01302,RC01545,RC02049,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiC,TP_methylase
IHAFMDNN_00633	1469948.JPNB01000001_gene2323	1.44e-89	284.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,36DM5@31979|Clostridiaceae	186801|Clostridia	H	Cobalamin biosynthesis protein cbiG	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
IHAFMDNN_00634	622312.ROSEINA2194_01854	3.25e-135	388.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia	186801|Clostridia	H	precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
IHAFMDNN_00635	622312.ROSEINA2194_01855	2.37e-168	483.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
IHAFMDNN_00636	622312.ROSEINA2194_01856	2.31e-103	304.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia	186801|Clostridia	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
IHAFMDNN_00637	1280673.AUJJ01000018_gene953	1.84e-18	85.5	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,4BYXB@830|Butyrivibrio	186801|Clostridia	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
IHAFMDNN_00638	397291.C804_03982	0.0	1013.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27K0D@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
IHAFMDNN_00639	585394.RHOM_03610	0.0	1995.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia	186801|Clostridia	L	DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
IHAFMDNN_00640	585394.RHOM_01255	2.82e-155	462.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
IHAFMDNN_00641	748224.HMPREF9436_00019	3.18e-193	539.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN2S@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IHAFMDNN_00642	1235793.C809_00895	4.8e-235	649.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27JHK@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IHAFMDNN_00643	1235793.C809_00894	8.03e-217	602.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,27II5@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
IHAFMDNN_00644	1235793.C809_00893	2.47e-188	527.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27KXN@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
IHAFMDNN_00645	478749.BRYFOR_05623	1.52e-177	501.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
IHAFMDNN_00646	478749.BRYFOR_05622	0.0	919.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,24A64@186801|Clostridia	186801|Clostridia	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
IHAFMDNN_00647	478749.BRYFOR_05621	1.39e-146	418.0	COG0584@1|root,COG0584@2|Bacteria,1V404@1239|Firmicutes,24EP5@186801|Clostridia	186801|Clostridia	C	Domain of unknown function	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
IHAFMDNN_00648	478749.BRYFOR_05620	2.49e-88	267.0	COG1234@1|root,COG1234@2|Bacteria,1V1J7@1239|Firmicutes,24F18@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2,UPF0227
IHAFMDNN_00649	936574.HMPREF1508_0912	4.87e-118	342.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia	186801|Clostridia	E	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
IHAFMDNN_00650	622312.ROSEINA2194_04392	2.7e-125	363.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
IHAFMDNN_00651	742765.HMPREF9457_01596	0.0	885.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,27WC8@189330|Dorea	186801|Clostridia	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
IHAFMDNN_00652	483218.BACPEC_01486	5.25e-184	518.0	28JHK@1|root,2Z9B4@2|Bacteria,1TS7Y@1239|Firmicutes,249S0@186801|Clostridia,26AQK@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00653	585394.RHOM_09105	3.73e-125	367.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
IHAFMDNN_00654	397290.C810_02092	4.31e-09	60.5	29N29@1|root,30900@2|Bacteria,1U486@1239|Firmicutes,24GD0@186801|Clostridia,27PVV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Stage III sporulation protein AB (spore_III_AB)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AB
IHAFMDNN_00655	585394.RHOM_09095	1.58e-33	115.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
IHAFMDNN_00656	585394.RHOM_09090	2.48e-45	150.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
IHAFMDNN_00657	622312.ROSEINA2194_04272	1.5e-310	848.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00658	483218.BACPEC_02218	1.63e-137	393.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_00659	483218.BACPEC_02217	1.5e-277	763.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,26A6P@186813|unclassified Clostridiales	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
IHAFMDNN_00660	483218.BACPEC_02216	6.18e-219	604.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,2685W@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
IHAFMDNN_00661	483218.BACPEC_02215	2.33e-149	420.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,269T7@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
IHAFMDNN_00662	585394.RHOM_12030	5.76e-120	348.0	COG1922@1|root,COG1922@2|Bacteria,1UIHR@1239|Firmicutes,25BDH@186801|Clostridia	186801|Clostridia	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	CoA_binding_3,Glyco_tran_WecB
IHAFMDNN_00663	585394.RHOM_12035	4.76e-91	278.0	2DMX9@1|root,32U7V@2|Bacteria,1W0SU@1239|Firmicutes,24QVG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00664	585394.RHOM_12040	4.26e-253	713.0	COG1132@1|root,COG1132@2|Bacteria,1TQAN@1239|Firmicutes,24BEK@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00665	585394.RHOM_12075	1.46e-107	320.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1VABR@1239|Firmicutes,24F51@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
IHAFMDNN_00666	1123307.KB904364_gene1166	4.82e-76	255.0	COG1807@1|root,COG1807@2|Bacteria,1V11Z@1239|Firmicutes,4ISNZ@91061|Bacilli	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
IHAFMDNN_00667	585394.RHOM_07875	0.0	923.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
IHAFMDNN_00668	585394.RHOM_07870	3.78e-126	362.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24E6I@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
IHAFMDNN_00669	585394.RHOM_07865	5.04e-278	761.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
IHAFMDNN_00670	585394.RHOM_07860	0.0	973.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
IHAFMDNN_00671	411468.CLOSCI_00849	1.51e-22	88.6	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,223NI@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IHAFMDNN_00672	411490.ANACAC_03749	6.72e-23	97.4	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24NSX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
IHAFMDNN_00673	622312.ROSEINA2194_03787	0.0	1269.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
IHAFMDNN_00674	622312.ROSEINA2194_03788	7.67e-87	257.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia	186801|Clostridia	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
IHAFMDNN_00675	622312.ROSEINA2194_03789	4.99e-117	343.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
IHAFMDNN_00676	33035.JPJF01000004_gene1973	4.25e-53	180.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia	186801|Clostridia	V	PFAM SCP-like extracellular	safA	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
IHAFMDNN_00677	622312.ROSEINA2194_00072	5.35e-161	455.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
IHAFMDNN_00678	1235790.C805_02231	1.28e-74	230.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
IHAFMDNN_00679	585394.RHOM_09760	4.84e-135	387.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
IHAFMDNN_00680	585394.RHOM_09755	6.79e-198	578.0	28J8T@1|root,2Z93Y@2|Bacteria,1UZBP@1239|Firmicutes,24F5R@186801|Clostridia	186801|Clostridia	S	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
IHAFMDNN_00681	585394.RHOM_09750	5.68e-49	157.0	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,24QSW@186801|Clostridia	186801|Clostridia	S	cytoplasmic domain of flagellar protein FhlB	flhB1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
IHAFMDNN_00682	622312.ROSEINA2194_00076	1.71e-55	175.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
IHAFMDNN_00683	622312.ROSEINA2194_00938	0.0	1188.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
IHAFMDNN_00684	622312.ROSEINA2194_00937	4.31e-143	416.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
IHAFMDNN_00685	585394.RHOM_06900	1.93e-233	657.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
IHAFMDNN_00686	622312.ROSEINA2194_00935	3.41e-95	282.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
IHAFMDNN_00688	585394.RHOM_09140	6.68e-155	440.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
IHAFMDNN_00690	585394.RHOM_09155	3.96e-159	449.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
IHAFMDNN_00691	622312.ROSEINA2194_01235	0.0	907.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia	186801|Clostridia	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
IHAFMDNN_00692	622312.ROSEINA2194_01722	7.94e-207	572.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
IHAFMDNN_00693	622312.ROSEINA2194_01725	0.0	1282.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
IHAFMDNN_00694	622312.ROSEINA2194_01728	1.22e-129	374.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_00695	622312.ROSEINA2194_01729	4.99e-179	502.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_00696	585394.RHOM_04815	1.14e-106	330.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
IHAFMDNN_00698	622312.ROSEINA2194_00293	9.74e-38	127.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
IHAFMDNN_00699	585394.RHOM_05135	0.0	1204.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
IHAFMDNN_00700	622312.ROSEINA2194_01402	2.8e-148	421.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_00701	585394.RHOM_06065	1.92e-257	715.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
IHAFMDNN_00702	585394.RHOM_06070	8.03e-295	805.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia	186801|Clostridia	G	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
IHAFMDNN_00703	585394.RHOM_06075	4.33e-195	541.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
IHAFMDNN_00704	471875.RUMLAC_00658	4.05e-59	187.0	COG1846@1|root,COG1846@2|Bacteria,1V9N7@1239|Firmicutes,24NET@186801|Clostridia,3WKTM@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
IHAFMDNN_00705	471875.RUMLAC_00657	2.99e-211	596.0	COG1102@1|root,COG2364@1|root,COG1102@2|Bacteria,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia,3WJRF@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	Cytidylate_kin2
IHAFMDNN_00706	585394.RHOM_13220	0.0	1055.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
IHAFMDNN_00707	411462.DORLON_02338	7.17e-295	806.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,27UZZ@189330|Dorea	186801|Clostridia	H	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
IHAFMDNN_00708	1280694.AUJQ01000020_gene6	1.81e-55	178.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia	186801|Clostridia	C	Bacterial transferase hexapeptide	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
IHAFMDNN_00709	411474.COPEUT_00684	2.98e-78	238.0	COG1102@1|root,COG1102@2|Bacteria,1V4ZA@1239|Firmicutes	1239|Firmicutes	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
IHAFMDNN_00710	883109.HMPREF0380_01476	2.18e-62	192.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3WDDV@538999|Clostridiales incertae sedis	186801|Clostridia	P	ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
IHAFMDNN_00712	585394.RHOM_04240	2.63e-49	169.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,249NK@186801|Clostridia	186801|Clostridia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
IHAFMDNN_00713	622312.ROSEINA2194_02268	2.33e-104	306.0	COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,24DB6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IHAFMDNN_00714	585394.RHOM_04250	1.37e-174	493.0	COG0618@1|root,COG0618@2|Bacteria,1UKBY@1239|Firmicutes,24EAR@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
IHAFMDNN_00715	585394.RHOM_04100	2.41e-170	480.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
IHAFMDNN_00716	585394.RHOM_04105	3.19e-158	447.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia	186801|Clostridia	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
IHAFMDNN_00718	585394.RHOM_04115	2.77e-238	663.0	COG5434@1|root,COG5434@2|Bacteria,1TRWY@1239|Firmicutes,24DY3@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00719	585394.RHOM_08330	1.61e-174	495.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
IHAFMDNN_00720	585394.RHOM_06405	6.83e-98	288.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IHAFMDNN_00721	585394.RHOM_09600	9.53e-253	696.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia	186801|Clostridia	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
IHAFMDNN_00722	585394.RHOM_09605	3.02e-169	478.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
IHAFMDNN_00723	585394.RHOM_09610	3.79e-100	292.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
IHAFMDNN_00724	585394.RHOM_09615	5.25e-117	339.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia	186801|Clostridia	V	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
IHAFMDNN_00725	585394.RHOM_09630	1.82e-130	386.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia	186801|Clostridia	E	oligoendopeptidase, M3 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
IHAFMDNN_00726	1235798.C817_02525	1.12e-08	52.0	2ERI6@1|root,33J3P@2|Bacteria,1VMBI@1239|Firmicutes,24VNP@186801|Clostridia,27VXK@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00727	585394.RHOM_08245	1.01e-81	244.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia	186801|Clostridia	S	Sporulation protein YtfJ	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
IHAFMDNN_00728	622312.ROSEINA2194_01756	3.74e-45	162.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
IHAFMDNN_00729	622312.ROSEINA2194_01757	4.77e-52	166.0	2CSSR@1|root,32SRT@2|Bacteria,1VKAJ@1239|Firmicutes,24N3Y@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00730	585394.RHOM_08260	1.99e-94	276.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IHAFMDNN_00731	585394.RHOM_08265	1.45e-237	667.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
IHAFMDNN_00732	585394.RHOM_08270	5.21e-225	632.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
IHAFMDNN_00733	585394.RHOM_08705	1.16e-52	169.0	2BZS0@1|root,343DQ@2|Bacteria,1VZ4U@1239|Firmicutes,25450@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00734	1235799.C818_02800	2.26e-96	296.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,27K01@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
IHAFMDNN_00735	97139.C824_04122	8.39e-77	234.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,24ICU@186801|Clostridia,36J7Y@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00736	1235792.C808_02507	6.24e-169	481.0	COG1216@1|root,COG1216@2|Bacteria,1VV6P@1239|Firmicutes,25EH9@186801|Clostridia,27JXT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_00737	585394.RHOM_08720	5.24e-66	216.0	2DBEW@1|root,2Z8UY@2|Bacteria,1UYFJ@1239|Firmicutes,2489J@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
IHAFMDNN_00738	622312.ROSEINA2194_01515	0.0	923.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia	186801|Clostridia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
IHAFMDNN_00740	622312.ROSEINA2194_01517	3.78e-143	407.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia	186801|Clostridia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
IHAFMDNN_00741	622312.ROSEINA2194_01518	4.04e-205	569.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia	186801|Clostridia	O	feS assembly protein SufB	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
IHAFMDNN_00742	1280681.AUJZ01000012_gene1135	7.94e-19	82.4	2ED22@1|root,2ZVQM@2|Bacteria,1W3EW@1239|Firmicutes,256YE@186801|Clostridia,4BZ46@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00743	556261.HMPREF0240_03527	1.45e-35	134.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia,36PCY@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
IHAFMDNN_00744	556261.HMPREF0240_03527	1.5e-221	627.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia,36PCY@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
IHAFMDNN_00745	1235793.C809_00600	1.7e-13	70.9	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,27IAA@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00746	397291.C804_04805	8.28e-168	483.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,27IAA@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00747	622312.ROSEINA2194_04371	2.92e-172	485.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IHAFMDNN_00749	1458427.BAWN01000009_gene613	1.47e-18	88.6	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,2VNH2@28216|Betaproteobacteria,4ACVV@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE2
IHAFMDNN_00750	518637.EUBIFOR_01475	8.05e-19	84.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,3VQ8R@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
IHAFMDNN_00752	585394.RHOM_08745	3.79e-92	291.0	28NI3@1|root,2ZBJM@2|Bacteria,1V27V@1239|Firmicutes,24FTG@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
IHAFMDNN_00753	585394.RHOM_08750	4.65e-142	406.0	COG1216@1|root,COG1216@2|Bacteria,1UAQP@1239|Firmicutes,25B5D@186801|Clostridia	186801|Clostridia	S	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_00754	585394.RHOM_08755	3.51e-166	479.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,24C11@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
IHAFMDNN_00755	1235802.C823_04311	1.87e-10	61.6	2EA00@1|root,3345F@2|Bacteria,1VJQ9@1239|Firmicutes,24R0V@186801|Clostridia,25Z91@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
IHAFMDNN_00756	585394.RHOM_08765	4.12e-170	489.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
IHAFMDNN_00757	622312.ROSEINA2194_02996	1.03e-166	471.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia	186801|Clostridia	J	S1 RNA binding domain protein	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
IHAFMDNN_00758	585394.RHOM_05400	7.13e-83	247.0	COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,24FR9@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
IHAFMDNN_00759	585394.RHOM_05405	6.43e-66	215.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia	186801|Clostridia	M	transglycosylase	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
IHAFMDNN_00760	585394.RHOM_05410	3.33e-136	390.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
IHAFMDNN_00761	585394.RHOM_05415	2.56e-53	169.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
IHAFMDNN_00762	622312.ROSEINA2194_00542	1.44e-186	528.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
IHAFMDNN_00763	585394.RHOM_11880	1.36e-254	701.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
IHAFMDNN_00764	1408312.JNJS01000004_gene2375	7.78e-170	476.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
IHAFMDNN_00765	622312.ROSEINA2194_01194	1.22e-41	138.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
IHAFMDNN_00766	585394.RHOM_13415	1.3e-111	321.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia	186801|Clostridia	S	ThiW protein	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
IHAFMDNN_00767	585394.RHOM_13420	1.61e-245	679.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia	186801|Clostridia	F	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
IHAFMDNN_00768	622312.ROSEINA2194_00222	5.78e-176	492.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
IHAFMDNN_00769	397288.C806_04417	1.39e-08	57.8	COG1132@1|root,COG1132@2|Bacteria,1US0C@1239|Firmicutes,24EZJ@186801|Clostridia,27M01@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
IHAFMDNN_00770	411489.CLOL250_00372	4e-232	644.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,36HCI@31979|Clostridiaceae	186801|Clostridia	T	Signal transduction histidine kinase	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_00771	411489.CLOL250_00371	1.17e-43	147.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,36HPB@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00772	622312.ROSEINA2194_02238	4.29e-120	353.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UXKB@1239|Firmicutes,24DXK@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
IHAFMDNN_00773	585394.RHOM_07120	1.2e-195	545.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
IHAFMDNN_00774	585394.RHOM_07115	8.24e-164	459.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
IHAFMDNN_00775	622312.ROSEINA2194_00984	1.59e-46	158.0	COG1559@1|root,COG1559@2|Bacteria,1VF4Y@1239|Firmicutes,24RCQ@186801|Clostridia	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	YceG
IHAFMDNN_00776	585394.RHOM_07105	7.12e-57	187.0	COG3064@1|root,COG3064@2|Bacteria,1V968@1239|Firmicutes,24KD3@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00777	585394.RHOM_07100	1.1e-32	117.0	2ECFD@1|root,336DM@2|Bacteria,1VHDX@1239|Firmicutes,24TE9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00778	585394.RHOM_05440	5.11e-219	606.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
IHAFMDNN_00780	622312.ROSEINA2194_01127	1.66e-153	434.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
IHAFMDNN_00781	585394.RHOM_05430	2.94e-267	744.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia	186801|Clostridia	P	Abc transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
IHAFMDNN_00782	585394.RHOM_04995	4.39e-85	258.0	COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes	1239|Firmicutes	F	COG0775 Nucleoside phosphorylase	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
IHAFMDNN_00783	469617.FUAG_02364	2.7e-140	416.0	COG0534@1|root,COG0534@2|Bacteria,37936@32066|Fusobacteria	32066|Fusobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00784	411489.CLOL250_02328	4.91e-77	236.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,36I0R@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
IHAFMDNN_00785	411489.CLOL250_02329	2.77e-170	481.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,36DZ4@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
IHAFMDNN_00786	411459.RUMOBE_03913	1.85e-226	627.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3XZ5Z@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
IHAFMDNN_00788	742765.HMPREF9457_00537	1.01e-67	219.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,27WJP@189330|Dorea	186801|Clostridia	P	Voltage gated chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
IHAFMDNN_00789	742765.HMPREF9457_00537	5.26e-76	239.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,27WJP@189330|Dorea	186801|Clostridia	P	Voltage gated chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
IHAFMDNN_00790	1256908.HMPREF0373_02751	1.64e-290	802.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,25V4N@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
IHAFMDNN_00791	189426.PODO_15400	1.26e-15	77.0	COG3507@1|root,COG3507@2|Bacteria,1UY12@1239|Firmicutes,4HEUT@91061|Bacilli,27497@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
IHAFMDNN_00792	1499968.TCA2_3001	1.51e-118	358.0	COG3507@1|root,COG3507@2|Bacteria,1UY12@1239|Firmicutes,4HEUT@91061|Bacilli,27497@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
IHAFMDNN_00793	585394.RHOM_09200	0.0	937.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
IHAFMDNN_00794	585394.RHOM_09205	0.0	1049.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
IHAFMDNN_00795	622312.ROSEINA2194_01246	4.57e-60	191.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
IHAFMDNN_00796	622312.ROSEINA2194_01247	1.13e-189	530.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
IHAFMDNN_00797	457421.CBFG_01718	0.0	1025.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
IHAFMDNN_00798	478749.BRYFOR_06209	7.92e-255	707.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
IHAFMDNN_00799	478749.BRYFOR_06207	1.32e-104	310.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
IHAFMDNN_00800	592026.GCWU0000282_002961	5.79e-139	423.0	COG1112@1|root,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia	186801|Clostridia	L	COG1112 Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
IHAFMDNN_00801	622312.ROSEINA2194_03578	0.0	941.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00802	622312.ROSEINA2194_03581	1.5e-10	60.8	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia	186801|Clostridia	K	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
IHAFMDNN_00803	622312.ROSEINA2194_03581	6.32e-151	436.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia	186801|Clostridia	K	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
IHAFMDNN_00804	585394.RHOM_06720	6.96e-196	546.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
IHAFMDNN_00805	622312.ROSEINA2194_04232	5.54e-126	365.0	COG2703@1|root,COG2703@2|Bacteria,1VBEC@1239|Firmicutes,24NV2@186801|Clostridia	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
IHAFMDNN_00806	585394.RHOM_08410	1.32e-253	698.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia	186801|Clostridia	C	decarboxylase beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
IHAFMDNN_00807	622312.ROSEINA2194_00498	4.57e-53	169.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia	186801|Clostridia	I	PFAM biotin lipoyl attachment domain-containing protein	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
IHAFMDNN_00808	585394.RHOM_08420	2.13e-95	286.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia	186801|Clostridia	P	decarboxylase gamma	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
IHAFMDNN_00809	585394.RHOM_08425	2.6e-290	799.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia	186801|Clostridia	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
IHAFMDNN_00810	585394.RHOM_08430	6.46e-178	507.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IHAFMDNN_00811	552398.HMPREF0866_00465	4.03e-13	77.4	28PI9@1|root,2ZC8C@2|Bacteria,1V36K@1239|Firmicutes,24K4U@186801|Clostridia,3WS08@541000|Ruminococcaceae	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
IHAFMDNN_00814	622312.ROSEINA2194_04219	0.0	1190.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_00815	585394.RHOM_10945	3.16e-250	689.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
IHAFMDNN_00816	622312.ROSEINA2194_02310	7.7e-264	727.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia	186801|Clostridia	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
IHAFMDNN_00818	585394.RHOM_09710	2.72e-121	357.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
IHAFMDNN_00819	585394.RHOM_09710	1.25e-155	446.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
IHAFMDNN_00820	585394.RHOM_09705	5.58e-125	359.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
IHAFMDNN_00821	585394.RHOM_09700	3.47e-208	579.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
IHAFMDNN_00822	1235802.C823_02304	5.72e-83	247.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
IHAFMDNN_00823	585394.RHOM_11245	8.06e-77	240.0	COG1345@1|root,COG1345@2|Bacteria,1V9AS@1239|Firmicutes,24MHW@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00824	622312.ROSEINA2194_01929	1.09e-231	640.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
IHAFMDNN_00825	585394.RHOM_11225	0.0	1296.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia	186801|Clostridia	E	MeTHIonine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
IHAFMDNN_00826	585394.RHOM_07960	2.15e-148	423.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia	186801|Clostridia	H	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
IHAFMDNN_00827	585394.RHOM_07965	2.11e-259	743.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia	186801|Clostridia	D	SpoIID LytB domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
IHAFMDNN_00828	1256908.HMPREF0373_02866	3.38e-133	392.0	COG0194@1|root,COG4502@1|root,COG0194@2|Bacteria,COG4502@2|Bacteria,1V87A@1239|Firmicutes,24SD2@186801|Clostridia	186801|Clostridia	F	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin,NT5C
IHAFMDNN_00829	1121115.AXVN01000012_gene3091	7.27e-15	68.9	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
IHAFMDNN_00830	537007.BLAHAN_06473	8.97e-150	425.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
IHAFMDNN_00831	1280698.AUJS01000004_gene2938	3.24e-238	661.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,27URQ@189330|Dorea	186801|Clostridia	C	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
IHAFMDNN_00832	411459.RUMOBE_00194	1.68e-68	215.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
IHAFMDNN_00833	622312.ROSEINA2194_02259	1.67e-80	249.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
IHAFMDNN_00834	622312.ROSEINA2194_02260	2.91e-158	447.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
IHAFMDNN_00835	585394.RHOM_09790	9.6e-38	127.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
IHAFMDNN_00836	622312.ROSEINA2194_00061	1.71e-49	157.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
IHAFMDNN_00837	622312.ROSEINA2194_00060	3.66e-271	748.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
IHAFMDNN_00838	585394.RHOM_09805	1.83e-62	193.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
IHAFMDNN_00840	585394.RHOM_09820	8.41e-116	342.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
IHAFMDNN_00841	622312.ROSEINA2194_00055	2.7e-98	296.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
IHAFMDNN_00842	622312.ROSEINA2194_00054	2.78e-58	188.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
IHAFMDNN_00843	622312.ROSEINA2194_03062	2.72e-224	621.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia	186801|Clostridia	C	3-dehydroquinate synthase	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
IHAFMDNN_00845	1410624.JNKK01000034_gene2571	1.52e-09	62.8	COG0531@1|root,COG0642@1|root,COG0784@1|root,COG0531@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I78@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg
IHAFMDNN_00847	585394.RHOM_03675	1.91e-85	255.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
IHAFMDNN_00848	585394.RHOM_03670	1.36e-46	152.0	2EJW5@1|root,33DKW@2|Bacteria,1VPSK@1239|Firmicutes,24W6H@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3837
IHAFMDNN_00849	585394.RHOM_03665	4.05e-55	176.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
IHAFMDNN_00850	585394.RHOM_03660	2.19e-103	304.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia	186801|Clostridia	S	COG NOG11305 non supervised orthologous group	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
IHAFMDNN_00852	585394.RHOM_11475	3.41e-150	433.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_00853	397291.C804_03204	0.0	1089.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,27I65@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IHAFMDNN_00854	585394.RHOM_11485	0.0	960.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IHAFMDNN_00855	585394.RHOM_16680	9.53e-236	670.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
IHAFMDNN_00856	622312.ROSEINA2194_04330	2.29e-171	481.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
IHAFMDNN_00857	642492.Clole_0437	4.05e-154	437.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
IHAFMDNN_00858	642492.Clole_0436	7.61e-134	385.0	COG0600@1|root,COG0600@2|Bacteria,1UYCY@1239|Firmicutes,249RH@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
IHAFMDNN_00859	642492.Clole_0435	5.72e-167	476.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
IHAFMDNN_00860	642492.Clole_0434	3.99e-54	171.0	COG0347@1|root,COG0347@2|Bacteria,1V73J@1239|Firmicutes,24S5C@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
IHAFMDNN_00861	642492.Clole_0433	2.32e-49	159.0	COG0347@1|root,COG0347@2|Bacteria,1VASB@1239|Firmicutes,24J84@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
IHAFMDNN_00862	642492.Clole_0432	2.44e-281	784.0	COG0154@1|root,COG0154@2|Bacteria,1TSAQ@1239|Firmicutes,2483V@186801|Clostridia	186801|Clostridia	J	PFAM Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
IHAFMDNN_00863	642492.Clole_0431	0.0	1902.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1TPUN@1239|Firmicutes,24E9Y@186801|Clostridia	186801|Clostridia	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
IHAFMDNN_00864	642492.Clole_0430	1.73e-139	395.0	COG3665@1|root,COG3665@2|Bacteria,1UYE1@1239|Firmicutes,24DNP@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 1	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
IHAFMDNN_00865	642492.Clole_0429	4.55e-155	437.0	COG3665@1|root,COG3665@2|Bacteria,1TQQF@1239|Firmicutes,24DHT@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 2	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
IHAFMDNN_00866	158189.SpiBuddy_2628	3.93e-09	58.5	COG2197@1|root,COG2197@2|Bacteria,2JATP@203691|Spirochaetes	203691|Spirochaetes	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
IHAFMDNN_00867	642492.Clole_0428	9.53e-61	197.0	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
IHAFMDNN_00868	1122915.AUGY01000071_gene4411	2.16e-40	148.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,4HCR6@91061|Bacilli,26S7G@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
IHAFMDNN_00869	478749.BRYFOR_07280	2.63e-30	112.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24A9U@186801|Clostridia	186801|Clostridia	Q	PFAM Isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
IHAFMDNN_00870	457421.CBFG_03614	6.18e-19	88.2	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
IHAFMDNN_00871	622312.ROSEINA2194_00855	9.51e-23	88.2	2EJZ9@1|root,33DPV@2|Bacteria,1VQST@1239|Firmicutes,254M5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00872	397290.C810_01918	1.16e-109	330.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes,24IM0@186801|Clostridia,27MBH@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IHAFMDNN_00873	1414720.CBYM010000015_gene2999	4.44e-120	350.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36DPF@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
IHAFMDNN_00874	1414720.CBYM010000015_gene3000	5.29e-139	404.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,36EF1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
IHAFMDNN_00875	1414720.CBYM010000015_gene3001	2.12e-138	402.0	COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,24A8W@186801|Clostridia,36FH9@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
IHAFMDNN_00876	1499683.CCFF01000013_gene228	2.56e-157	450.0	COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,24B1M@186801|Clostridia,36EU7@31979|Clostridiaceae	186801|Clostridia	P	Periplasmic binding protein	fhuD	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
IHAFMDNN_00877	1408422.JHYF01000008_gene3641	1.04e-89	280.0	COG2207@1|root,COG2207@2|Bacteria,1V0EE@1239|Firmicutes,25B24@186801|Clostridia,36FJY@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
IHAFMDNN_00878	585394.RHOM_16690	4.43e-144	411.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
IHAFMDNN_00879	622312.ROSEINA2194_04328	4.33e-155	437.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia	186801|Clostridia	S	Methyltransferase	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
IHAFMDNN_00880	622312.ROSEINA2194_04327	6.41e-189	528.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia	186801|Clostridia	K	domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
IHAFMDNN_00881	622312.ROSEINA2194_04326	1.6e-96	289.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
IHAFMDNN_00882	626939.HMPREF9443_01887	5.98e-87	270.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4H521@909932|Negativicutes	909932|Negativicutes	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
IHAFMDNN_00883	1256908.HMPREF0373_01761	3.76e-80	239.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,25X6H@186806|Eubacteriaceae	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
IHAFMDNN_00884	658088.HMPREF0987_01753	2.52e-109	329.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,27IWC@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
IHAFMDNN_00885	411469.EUBHAL_01351	3.87e-195	546.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25VS2@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
IHAFMDNN_00886	657322.FPR_30730	3.55e-125	364.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
IHAFMDNN_00887	1256908.HMPREF0373_00762	3.84e-29	105.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
IHAFMDNN_00888	622312.ROSEINA2194_02025	2.11e-130	382.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
IHAFMDNN_00889	585394.RHOM_14795	1.38e-19	79.7	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00890	397291.C804_00046	2.68e-120	358.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27KG8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
IHAFMDNN_00891	1235798.C817_05303	1.62e-31	118.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27VVU@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
IHAFMDNN_00892	411489.CLOL250_02333	2.53e-121	368.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,36FB9@31979|Clostridiaceae	186801|Clostridia	EG	DMT(Drug metabolite transporter) superfamily permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IHAFMDNN_00893	1256908.HMPREF0373_03204	0.0	1030.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
IHAFMDNN_00894	585394.RHOM_11610	9.58e-271	744.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
IHAFMDNN_00896	658088.HMPREF0987_01444	0.0	1462.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,27I5Y@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
IHAFMDNN_00898	585394.RHOM_02755	7.79e-209	589.0	COG2206@1|root,COG2206@2|Bacteria,1UUCI@1239|Firmicutes,24CPS@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
IHAFMDNN_00899	585394.RHOM_02740	0.0	1355.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
IHAFMDNN_00900	1382315.JPOI01000001_gene107	1.57e-83	263.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,1WFIB@129337|Geobacillus	91061|Bacilli	K	helix_turn _helix lactose operon repressor	cytR	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IHAFMDNN_00901	1280696.ATVY01000004_gene422	2.2e-98	291.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,4BY5V@830|Butyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
IHAFMDNN_00902	585394.RHOM_03595	1.7e-171	482.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
IHAFMDNN_00903	483218.BACPEC_01903	7.63e-266	734.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,2685U@186813|unclassified Clostridiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_00904	622312.ROSEINA2194_02475	3.05e-89	284.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
IHAFMDNN_00905	1294142.CINTURNW_3431	1.72e-312	863.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,36DVT@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
IHAFMDNN_00906	585394.RHOM_03115	1.01e-64	199.0	COG1917@1|root,COG1917@2|Bacteria,1VCF2@1239|Firmicutes,25BAE@186801|Clostridia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
IHAFMDNN_00907	622312.ROSEINA2194_02021	1.63e-186	529.0	COG0738@1|root,COG0738@2|Bacteria,1UZWI@1239|Firmicutes,24H3U@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IHAFMDNN_00908	585394.RHOM_03110	4.45e-162	462.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia	186801|Clostridia	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
IHAFMDNN_00909	585394.RHOM_03105	1.46e-43	149.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V1DC@1239|Firmicutes,24GJV@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
IHAFMDNN_00910	622312.ROSEINA2194_00858	0.0	892.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
IHAFMDNN_00911	585394.RHOM_15935	3.98e-73	231.0	2C331@1|root,30RPK@2|Bacteria,1V3YF@1239|Firmicutes,24IF9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00913	585394.RHOM_15910	8.34e-168	479.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IHAFMDNN_00914	585394.RHOM_15905	2.78e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_00915	585394.RHOM_15900	0.0	977.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
IHAFMDNN_00916	585394.RHOM_15890	0.0	1386.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
IHAFMDNN_00917	585394.RHOM_15875	3.08e-201	571.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
IHAFMDNN_00918	585394.RHOM_15870	0.0	1025.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
IHAFMDNN_00919	585394.RHOM_15865	0.0	1209.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
IHAFMDNN_00920	585394.RHOM_15860	0.0	1042.0	28ISF@1|root,2Z8RM@2|Bacteria,1TSK2@1239|Firmicutes,249Q2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00921	622312.ROSEINA2194_00744	1.6e-100	299.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia	186801|Clostridia	M	N-Acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
IHAFMDNN_00922	585394.RHOM_15850	7.72e-298	828.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia	186801|Clostridia	M	family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
IHAFMDNN_00924	622312.ROSEINA2194_00750	1.1e-31	116.0	29UTA@1|root,30G5N@2|Bacteria,1UF82@1239|Firmicutes,24U6Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00925	622312.ROSEINA2194_00751	1.54e-136	407.0	COG0515@1|root,COG0515@2|Bacteria,1V3N4@1239|Firmicutes,25B6W@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
IHAFMDNN_00926	585394.RHOM_11645	2.12e-281	778.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia	186801|Clostridia	H	coproporphyrinogen	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
IHAFMDNN_00927	585394.RHOM_11650	1.92e-123	354.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
IHAFMDNN_00928	622312.ROSEINA2194_02168	0.0	1384.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
IHAFMDNN_00929	585394.RHOM_13035	1e-87	264.0	COG4905@1|root,COG4905@2|Bacteria,1VI7C@1239|Firmicutes,25CKG@186801|Clostridia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IHAFMDNN_00930	622312.ROSEINA2194_00215	1.8e-103	301.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
IHAFMDNN_00931	622312.ROSEINA2194_02123	2.3e-44	144.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
IHAFMDNN_00933	1410628.JNKS01000007_gene1428	1.09e-12	67.8	2BZT8@1|root,32W5F@2|Bacteria,1UGQC@1239|Firmicutes,24Q23@186801|Clostridia,27RY9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
IHAFMDNN_00934	1280698.AUJS01000027_gene2309	1.95e-131	422.0	COG1196@1|root,COG1196@2|Bacteria,1UJ26@1239|Firmicutes,25EV1@186801|Clostridia,27WJD@189330|Dorea	186801|Clostridia	D	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,FIVAR,FMN_bind,PBP-Tp47_a,PBP-Tp47_c
IHAFMDNN_00935	585394.RHOM_11450	6.77e-247	683.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
IHAFMDNN_00936	1410616.JHXE01000013_gene255	8.06e-162	458.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3NGCJ@46205|Pseudobutyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IHAFMDNN_00937	1469948.JPNB01000002_gene3876	3.3e-178	503.0	COG1175@1|root,COG1175@2|Bacteria,1TQHI@1239|Firmicutes,247ZB@186801|Clostridia,36HT0@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
IHAFMDNN_00938	1280673.AUJJ01000009_gene3083	1.31e-237	667.0	COG1653@1|root,COG1653@2|Bacteria,1TS0C@1239|Firmicutes,249WW@186801|Clostridia,4BZ2U@830|Butyrivibrio	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
IHAFMDNN_00939	388467.A19Y_0928	5.06e-106	321.0	COG0451@1|root,COG0451@2|Bacteria,1G3VX@1117|Cyanobacteria,1HE17@1150|Oscillatoriales	1117|Cyanobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
IHAFMDNN_00940	658655.HMPREF0988_02467	0.0	990.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,248Z9@186801|Clostridia,27IBW@186928|unclassified Lachnospiraceae	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IHAFMDNN_00941	397291.C804_04439	6.4e-298	815.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,27JAE@186928|unclassified Lachnospiraceae	186801|Clostridia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	rfbH	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
IHAFMDNN_00942	553973.CLOHYLEM_06245	5.15e-106	311.0	COG1208@1|root,COG1208@2|Bacteria,1TPII@1239|Firmicutes,249GT@186801|Clostridia,21YI5@1506553|Lachnoclostridium	186801|Clostridia	JM	Nucleotidyl transferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
IHAFMDNN_00943	585394.RHOM_16730	1.8e-72	232.0	2EE0F@1|root,337V8@2|Bacteria,1VFWV@1239|Firmicutes,24SC3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00944	622312.ROSEINA2194_04322	2.62e-96	293.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	DUF3305,NTP_transf_3
IHAFMDNN_00945	622312.ROSEINA2194_04323	3.69e-206	588.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
IHAFMDNN_00946	622312.ROSEINA2194_04324	1.47e-96	286.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
IHAFMDNN_00947	622312.ROSEINA2194_04325	4.89e-82	244.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,24S6C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
IHAFMDNN_00948	585394.RHOM_10025	2.15e-196	567.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
IHAFMDNN_00949	622312.ROSEINA2194_03530	7.57e-91	268.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IHAFMDNN_00950	585394.RHOM_10015	5.63e-178	501.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
IHAFMDNN_00951	622312.ROSEINA2194_03528	4.26e-143	406.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
IHAFMDNN_00952	622312.ROSEINA2194_03527	3.24e-201	570.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
IHAFMDNN_00953	585394.RHOM_02500	6.4e-30	108.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IHAFMDNN_00954	585394.RHOM_02505	7.65e-182	509.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
IHAFMDNN_00955	585394.RHOM_02510	1.4e-201	558.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
IHAFMDNN_00956	585394.RHOM_02515	0.0	1233.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
IHAFMDNN_00957	608534.GCWU000341_02282	4.77e-56	197.0	COG5281@1|root,COG5281@2|Bacteria,1TPWF@1239|Firmicutes,24A8R@186801|Clostridia	186801|Clostridia	S	tape measure	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
IHAFMDNN_00958	742740.HMPREF9474_02343	8.46e-84	255.0	COG1652@1|root,COG1652@2|Bacteria,1V78C@1239|Firmicutes,24JMB@186801|Clostridia,2211Q@1506553|Lachnoclostridium	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IHAFMDNN_00959	1029718.SFBM_0133	1.11e-129	379.0	COG4193@1|root,COG4193@2|Bacteria,1TYY9@1239|Firmicutes,248KE@186801|Clostridia,36FSI@31979|Clostridiaceae	186801|Clostridia	G	PFAM Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23
IHAFMDNN_00960	357809.Cphy_0791	2.86e-17	77.8	2E4UZ@1|root,32ZPC@2|Bacteria,1VFDY@1239|Firmicutes,24R3J@186801|Clostridia,221H3@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2577)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2577
IHAFMDNN_00961	272563.CD630_09630	1.07e-40	139.0	COG3628@1|root,COG3628@2|Bacteria,1V9Z3@1239|Firmicutes,24MZA@186801|Clostridia,25U3E@186804|Peptostreptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
IHAFMDNN_00962	1449050.JNLE01000005_gene4831	1.17e-107	325.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,36FT3@31979|Clostridiaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
IHAFMDNN_00963	1163671.JAGI01000002_gene2842	8.75e-34	126.0	2DP8K@1|root,3310Z@2|Bacteria,1UM2Y@1239|Firmicutes,25GVV@186801|Clostridia	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
IHAFMDNN_00965	585394.RHOM_06845	3.1e-199	565.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
IHAFMDNN_00966	585394.RHOM_06850	2.35e-215	617.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
IHAFMDNN_00967	877415.JNJQ01000002_gene2280	1.53e-230	638.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,3VPNW@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the dehydration of D-mannonate	uxuA	-	-	-	-	-	-	-	-	-	-	-	UxuA
IHAFMDNN_00968	585394.RHOM_12655	2.16e-112	333.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes	1239|Firmicutes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IHAFMDNN_00969	585394.RHOM_12660	3.77e-122	353.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
IHAFMDNN_00970	585394.RHOM_12665	1.17e-51	166.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
IHAFMDNN_00971	622312.ROSEINA2194_03041	3.82e-155	452.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
IHAFMDNN_00972	994573.T472_0204750	1.66e-07	52.0	COG1896@1|root,COG1896@2|Bacteria,1UIAE@1239|Firmicutes,25EFH@186801|Clostridia,36UNZ@31979|Clostridiaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
IHAFMDNN_00973	585394.RHOM_04850	0.0	1154.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00974	585394.RHOM_04855	0.0	988.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_00975	585394.RHOM_04860	6.43e-63	197.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
IHAFMDNN_00976	622312.ROSEINA2194_01478	2.37e-203	588.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
IHAFMDNN_00977	585394.RHOM_08575	0.0	914.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
IHAFMDNN_00978	585394.RHOM_02970	2.3e-41	138.0	2C1ED@1|root,33FE6@2|Bacteria,1VKWJ@1239|Firmicutes,24VDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_00979	585394.RHOM_08205	1.74e-289	796.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia	186801|Clostridia	G	D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
IHAFMDNN_00980	585394.RHOM_04075	9.67e-177	494.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
IHAFMDNN_00981	1235793.C809_01107	7.58e-202	575.0	COG1680@1|root,COG1680@2|Bacteria,1TSXS@1239|Firmicutes,24H20@186801|Clostridia	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
IHAFMDNN_00982	1055815.AYYA01000008_gene2221	2.65e-08	55.8	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,1T1VS@1236|Gammaproteobacteria,3NTMP@468|Moraxellaceae	1236|Gammaproteobacteria	K	AraC-type transcriptional regulator N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
IHAFMDNN_00983	585394.RHOM_05640	1.11e-41	138.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
IHAFMDNN_00984	585394.RHOM_05645	2.58e-183	516.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
IHAFMDNN_00985	585394.RHOM_05650	1.48e-167	485.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
IHAFMDNN_00986	585394.RHOM_05655	2.89e-78	238.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
IHAFMDNN_00987	622312.ROSEINA2194_03960	1.29e-141	418.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia	186801|Clostridia	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
IHAFMDNN_00988	585394.RHOM_10935	8.53e-183	520.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia	186801|Clostridia	G	UDPglucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
IHAFMDNN_00989	585394.RHOM_10930	3.4e-248	686.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia	186801|Clostridia	E	Aminotransferase	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IHAFMDNN_00990	622312.ROSEINA2194_02313	6.58e-217	603.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
IHAFMDNN_00991	585394.RHOM_10920	1.9e-97	296.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IHAFMDNN_00992	1410633.JHWR01000001_gene1255	9.98e-126	392.0	COG2200@1|root,COG2200@2|Bacteria,1V15N@1239|Firmicutes,24C2G@186801|Clostridia,27K15@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
IHAFMDNN_00993	585394.RHOM_06170	0.0	1019.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53
IHAFMDNN_00994	1298920.KI911353_gene1795	3.66e-171	496.0	COG1653@1|root,COG1653@2|Bacteria,1V5R7@1239|Firmicutes,25BSW@186801|Clostridia,221PP@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
IHAFMDNN_00995	610130.Closa_1668	1.23e-135	394.0	COG1175@1|root,COG1175@2|Bacteria,1V0JI@1239|Firmicutes,25C5R@186801|Clostridia,2200H@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
IHAFMDNN_00996	1298920.KI911353_gene1797	3.04e-134	389.0	COG0395@1|root,COG0395@2|Bacteria,1V2Q1@1239|Firmicutes,24A8E@186801|Clostridia,2202Q@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
IHAFMDNN_00998	585394.RHOM_08550	1.06e-267	740.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IHAFMDNN_00999	1280694.AUJQ01000008_gene158	5.37e-246	690.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia,3NGF5@46205|Pseudobutyrivibrio	186801|Clostridia	G	C-terminal of Glycosyl hydrolases family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
IHAFMDNN_01000	622312.ROSEINA2194_00234	5.96e-135	393.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
IHAFMDNN_01001	903814.ELI_1175	9.76e-52	204.0	COG3209@1|root,COG3209@2|Bacteria,1UK8Y@1239|Firmicutes,24M4J@186801|Clostridia,25XIP@186806|Eubacteriaceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Flg_new,LRR_5
IHAFMDNN_01002	180332.JTGN01000011_gene619	1.5e-35	155.0	COG4870@1|root,COG5492@1|root,COG4870@2|Bacteria,COG5492@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
IHAFMDNN_01003	1449050.JNLE01000003_gene678	1.71e-191	558.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
IHAFMDNN_01004	1449050.JNLE01000003_gene677	5.38e-172	509.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
IHAFMDNN_01005	1541959.KQ51_01201	9.16e-98	295.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K11614	ko02020,map02020	M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9,SPOB_a
IHAFMDNN_01006	1449050.JNLE01000003_gene675	2.01e-75	235.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,36KUT@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
IHAFMDNN_01007	622312.ROSEINA2194_04066	1.33e-63	221.0	COG0840@1|root,COG0840@2|Bacteria,1V0JG@1239|Firmicutes,24A5M@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
IHAFMDNN_01008	1235798.C817_05228	6.81e-117	350.0	COG0662@1|root,COG2169@1|root,COG0662@2|Bacteria,COG2169@2|Bacteria,1V9CR@1239|Firmicutes,24K6B@186801|Clostridia,27WPH@189330|Dorea	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
IHAFMDNN_01009	1226325.HMPREF1548_05583	0.0	1424.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,36G82@31979|Clostridiaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
IHAFMDNN_01010	536227.CcarbDRAFT_0112	5.04e-22	95.5	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,24IYG@186801|Clostridia,36GVF@31979|Clostridiaceae	186801|Clostridia	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
IHAFMDNN_01011	1117379.BABA_02757	2.41e-16	80.5	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,4HCZS@91061|Bacilli,1ZDGN@1386|Bacillus	91061|Bacilli	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
IHAFMDNN_01012	702450.CUW_0318	3.91e-17	79.7	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,3VTTK@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IHAFMDNN_01013	411489.CLOL250_02048	1.52e-18	100.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1W1CQ@1239|Firmicutes,24Q72@186801|Clostridia,36NF6@31979|Clostridiaceae	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01015	585501.HMPREF6123_1167	6.94e-118	341.0	28KQ0@1|root,2ZA7Z@2|Bacteria,1V4X7@1239|Firmicutes,24E87@186801|Clostridia,2PTNA@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
IHAFMDNN_01016	518637.EUBIFOR_02026	3.97e-77	231.0	29AZ1@1|root,2ZXY1@2|Bacteria,1V4KY@1239|Firmicutes,3VTCC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01017	622312.ROSEINA2194_03057	9.3e-180	508.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
IHAFMDNN_01019	622312.ROSEINA2194_03059	4.02e-189	528.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_01020	585394.RHOM_12825	4.14e-150	429.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IHAFMDNN_01021	622312.ROSEINA2194_00531	9.66e-68	209.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01023	622312.ROSEINA2194_01915	9.19e-55	195.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
IHAFMDNN_01025	585394.RHOM_03830	1.78e-290	806.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
IHAFMDNN_01028	1235792.C808_01660	2.49e-193	542.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,27JZ4@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
IHAFMDNN_01029	1298920.KI911353_gene785	6.48e-176	501.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z7G@1506553|Lachnoclostridium	186801|Clostridia	E	Cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
IHAFMDNN_01030	1256908.HMPREF0373_01402	7.37e-99	293.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
IHAFMDNN_01031	1298920.KI911353_gene811	2.79e-76	231.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,21Z3U@1506553|Lachnoclostridium	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
IHAFMDNN_01032	1235793.C809_00618	8.16e-70	215.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,27MYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
IHAFMDNN_01033	471875.RUMLAC_02383	1.14e-236	660.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3WHBW@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
IHAFMDNN_01034	585394.RHOM_01185	6.26e-244	677.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
IHAFMDNN_01035	411461.DORFOR_01502	9.2e-115	336.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,27WS8@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
IHAFMDNN_01036	585394.RHOM_01170	8.9e-124	357.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
IHAFMDNN_01037	622312.ROSEINA2194_01501	0.0	1144.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
IHAFMDNN_01038	585394.RHOM_02390	2.59e-201	585.0	COG2206@1|root,COG2206@2|Bacteria,1V6IE@1239|Firmicutes,24K4Y@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IHAFMDNN_01040	515620.EUBELI_20549	0.0	948.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25UVM@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01041	515620.EUBELI_20548	0.0	1045.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UTB@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01042	515620.EUBELI_20547	1.12e-62	196.0	COG1846@1|root,COG1846@2|Bacteria,1VGNE@1239|Firmicutes,25MX1@186801|Clostridia,25Z6W@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01043	585394.RHOM_08960	1.08e-271	750.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
IHAFMDNN_01044	585394.RHOM_08955	6.1e-53	169.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IHAFMDNN_01047	622312.ROSEINA2194_01218	2.53e-217	605.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
IHAFMDNN_01048	622312.ROSEINA2194_01217	2.54e-75	232.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia	186801|Clostridia	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
IHAFMDNN_01049	585394.RHOM_15750	4.56e-41	155.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
IHAFMDNN_01050	622312.ROSEINA2194_00769	2.46e-155	447.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
IHAFMDNN_01051	585394.RHOM_15740	2.5e-200	559.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1TT0Y@1239|Firmicutes,247MH@186801|Clostridia	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
IHAFMDNN_01052	622312.ROSEINA2194_00772	3.52e-85	252.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
IHAFMDNN_01053	585394.RHOM_15725	1.15e-211	590.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
IHAFMDNN_01055	585394.RHOM_15710	3.05e-143	425.0	COG3103@1|root,COG3773@1|root,COG3103@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24DDK@186801|Clostridia	186801|Clostridia	MT	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2,SH3_3
IHAFMDNN_01056	585394.RHOM_14285	2.44e-225	624.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
IHAFMDNN_01057	1235793.C809_02063	5.49e-123	354.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,27IZY@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	graR	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_01058	585394.RHOM_14275	1.95e-102	312.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
IHAFMDNN_01059	1256908.HMPREF0373_02016	1.12e-69	217.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01060	1499683.CCFF01000017_gene1679	1.08e-66	209.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,36DTD@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01061	585394.RHOM_14265	9.8e-219	634.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
IHAFMDNN_01062	140626.JHWB01000022_gene2115	2.9e-97	288.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
IHAFMDNN_01064	585394.RHOM_14220	2.78e-194	546.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia	186801|Clostridia	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
IHAFMDNN_01065	585394.RHOM_14215	4.32e-53	178.0	2DU28@1|root,33NME@2|Bacteria,1VMV6@1239|Firmicutes,24V3C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01066	622312.ROSEINA2194_04052	1.76e-61	193.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
IHAFMDNN_01067	585394.RHOM_14205	4.33e-154	438.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
IHAFMDNN_01068	585394.RHOM_14200	3.1e-185	519.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
IHAFMDNN_01069	585394.RHOM_14195	2.6e-149	429.0	COG0770@1|root,COG0770@2|Bacteria,1TS8M@1239|Firmicutes,24CJW@186801|Clostridia	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
IHAFMDNN_01070	622312.ROSEINA2194_04045	0.0	916.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
IHAFMDNN_01071	585394.RHOM_14185	6.92e-119	351.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
IHAFMDNN_01073	411468.CLOSCI_00298	3.25e-54	179.0	2CWYZ@1|root,32T0P@2|Bacteria,1VYWB@1239|Firmicutes,24SU1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01076	1235793.C809_02647	3.55e-152	435.0	COG1032@1|root,COG1032@2|Bacteria,1TRY3@1239|Firmicutes,249Q1@186801|Clostridia,27JZG@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01077	411468.CLOSCI_00302	7.98e-120	350.0	COG0338@1|root,COG0338@2|Bacteria,1UBIY@1239|Firmicutes,24D2Y@186801|Clostridia,223ZF@1506553|Lachnoclostridium	186801|Clostridia	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
IHAFMDNN_01078	1280676.AUJO01000001_gene2223	2.36e-314	866.0	COG1653@1|root,COG1653@2|Bacteria,1TR5P@1239|Firmicutes,24F0C@186801|Clostridia,4C20R@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502,SBP_bac_1
IHAFMDNN_01079	1280685.AUKC01000052_gene1365	1.76e-177	499.0	COG0395@1|root,COG0395@2|Bacteria,1TS9S@1239|Firmicutes,24BF3@186801|Clostridia,4BWPH@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_01080	515622.bpr_I0935	2.05e-177	503.0	COG4209@1|root,COG4209@2|Bacteria,1TT63@1239|Firmicutes,25C4W@186801|Clostridia,4BW6J@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_01081	1121115.AXVN01000012_gene3113	4.57e-188	527.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
IHAFMDNN_01082	140626.JHWB01000013_gene760	5.22e-295	813.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
IHAFMDNN_01083	1280688.AUJB01000008_gene632	1.14e-29	107.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24UPV@186801|Clostridia,3NIA5@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01084	1410625.JHWK01000005_gene1207	1.47e-169	479.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,27K27@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
IHAFMDNN_01085	622312.ROSEINA2194_02152	2e-61	192.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
IHAFMDNN_01086	585394.RHOM_04685	1.12e-132	387.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
IHAFMDNN_01087	1235792.C808_00459	1.59e-201	567.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,27IBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
IHAFMDNN_01088	585394.RHOM_06135	0.0	1197.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
IHAFMDNN_01089	585394.RHOM_07555	4.22e-51	162.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
IHAFMDNN_01090	585394.RHOM_07560	7.71e-85	257.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IHAFMDNN_01091	585394.RHOM_07565	8.96e-103	301.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia	186801|Clostridia	H	Hydrolase, HD family	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
IHAFMDNN_01092	585394.RHOM_07570	1.3e-62	193.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
IHAFMDNN_01093	585394.RHOM_07575	1.09e-127	365.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
IHAFMDNN_01094	658086.HMPREF0994_02833	6.28e-20	85.1	COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,24UT1@186801|Clostridia,27Q7D@186928|unclassified Lachnospiraceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IHAFMDNN_01095	585394.RHOM_07585	9.78e-150	424.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
IHAFMDNN_01096	411474.COPEUT_00629	7.17e-22	95.9	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
IHAFMDNN_01097	1410632.JHWW01000013_gene237	8.08e-13	68.9	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,27NJZ@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
IHAFMDNN_01098	411462.DORLON_00099	1.45e-201	564.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
IHAFMDNN_01099	585394.RHOM_04700	3.41e-186	533.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IHAFMDNN_01100	585394.RHOM_02460	0.0	1011.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
IHAFMDNN_01101	1408306.JHXX01000009_gene3377	1.08e-92	287.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,4BWSH@830|Butyrivibrio	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
IHAFMDNN_01102	585394.RHOM_02455	1.51e-35	120.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01104	411474.COPEUT_02877	8.21e-17	73.6	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
IHAFMDNN_01105	585394.RHOM_02440	5.61e-98	288.0	COG1451@1|root,COG1451@2|Bacteria,1UJII@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
IHAFMDNN_01106	1139219.I569_00581	4.22e-58	197.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,4HA00@91061|Bacilli,4AZ8X@81852|Enterococcaceae	91061|Bacilli	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
IHAFMDNN_01107	641107.CDLVIII_5796	8.75e-118	350.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,36H24@31979|Clostridiaceae	186801|Clostridia	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
IHAFMDNN_01108	908340.HMPREF9406_0793	2.66e-145	453.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,36FMM@31979|Clostridiaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01109	1158601.I585_00435	0.0	983.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,4HBZY@91061|Bacilli,4B0FA@81852|Enterococcaceae	91061|Bacilli	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
IHAFMDNN_01110	658659.HMPREF0983_03979	2.96e-38	132.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,3VQEW@526524|Erysipelotrichia	1239|Firmicutes	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
IHAFMDNN_01112	1121090.KB894686_gene2838	7.07e-149	439.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,4HCHD@91061|Bacilli,1ZSHH@1386|Bacillus	91061|Bacilli	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Omega_Repress,Rep_trans
IHAFMDNN_01114	411461.DORFOR_03093	5.01e-138	411.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27V96@189330|Dorea	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
IHAFMDNN_01115	169963.lmo1113	1.27e-34	124.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,4HG1A@91061|Bacilli	91061|Bacilli	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
IHAFMDNN_01116	169963.lmo1114	4.02e-34	120.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,4HH9J@91061|Bacilli	91061|Bacilli	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
IHAFMDNN_01128	536233.CLO_3167	2.88e-23	101.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,36UPV@31979|Clostridiaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01129	483218.BACPEC_02162	6.05e-07	52.4	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01130	622312.ROSEINA2194_01205	0.0	1191.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IHAFMDNN_01132	622312.ROSEINA2194_01477	1.04e-110	323.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
IHAFMDNN_01133	585394.RHOM_02305	0.0	909.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
IHAFMDNN_01134	397291.C804_00766	7.16e-231	696.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1VQTU@1239|Firmicutes,24D8M@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IHAFMDNN_01135	622312.ROSEINA2194_01481	3.66e-244	679.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
IHAFMDNN_01136	585394.RHOM_02315	7.31e-144	417.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia	186801|Clostridia	S	spore coat protein, CotS	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
IHAFMDNN_01137	585394.RHOM_02320	2.38e-136	408.0	28JT6@1|root,2Z9II@2|Bacteria,1V7ZW@1239|Firmicutes,24H3G@186801|Clostridia	186801|Clostridia	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
IHAFMDNN_01138	585394.RHOM_02325	2.13e-224	630.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IHAFMDNN_01139	622312.ROSEINA2194_01484	3.53e-144	422.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
IHAFMDNN_01140	622312.ROSEINA2194_01485	1.04e-50	161.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
IHAFMDNN_01141	585394.RHOM_02340	2.46e-44	144.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
IHAFMDNN_01142	622312.ROSEINA2194_01487	1.24e-51	164.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
IHAFMDNN_01143	622312.ROSEINA2194_01488	1.13e-53	173.0	2EFTM@1|root,32YR5@2|Bacteria,1VEV2@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
IHAFMDNN_01144	622312.ROSEINA2194_01489	2.92e-34	120.0	COG2919@1|root,COG2919@2|Bacteria,1VGPP@1239|Firmicutes,24R6M@186801|Clostridia	186801|Clostridia	D	septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
IHAFMDNN_01145	622312.ROSEINA2194_01490	5.33e-213	591.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
IHAFMDNN_01146	622312.ROSEINA2194_01491	4.75e-310	860.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia	186801|Clostridia	KT	stage ii sporulation protein e	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
IHAFMDNN_01147	585394.RHOM_02375	8.04e-162	474.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
IHAFMDNN_01148	585394.RHOM_02380	9.54e-101	294.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
IHAFMDNN_01149	585394.RHOM_02385	0.0	1014.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IHAFMDNN_01150	622312.ROSEINA2194_03697	3.7e-119	347.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IHAFMDNN_01151	622312.ROSEINA2194_03698	0.0	1143.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
IHAFMDNN_01152	585394.RHOM_07410	2.98e-148	427.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IHAFMDNN_01153	658655.HMPREF0988_01291	7.77e-130	377.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,25E9N@186801|Clostridia,27UHQ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	ARD,AraC_binding,Cupin_2,HTH_18
IHAFMDNN_01154	658088.HMPREF0987_02461	1.17e-167	472.0	COG1402@1|root,COG1402@2|Bacteria,1UDUM@1239|Firmicutes,2494R@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
IHAFMDNN_01155	658088.HMPREF0987_02460	7.06e-128	372.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
IHAFMDNN_01156	658088.HMPREF0987_02459	1.5e-266	737.0	COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,25C8G@186801|Clostridia,27KBK@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
IHAFMDNN_01157	1280696.ATVY01000019_gene2854	1.36e-44	147.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,4BZH5@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
IHAFMDNN_01159	457412.RSAG_02065	1.69e-35	144.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,25DEX@186801|Clostridia,3WSGH@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
IHAFMDNN_01160	585394.RHOM_04000	1.62e-131	387.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
IHAFMDNN_01161	622312.ROSEINA2194_04459	2.09e-224	620.0	COG0524@1|root,COG0524@2|Bacteria,1TQ9Q@1239|Firmicutes,25B0T@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
IHAFMDNN_01162	622312.ROSEINA2194_00427	1.64e-276	768.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IHAFMDNN_01163	585394.RHOM_00920	3.83e-217	608.0	COG4641@1|root,COG4641@2|Bacteria,1V0EG@1239|Firmicutes,24DZB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
IHAFMDNN_01164	585394.RHOM_08000	2.11e-59	186.0	COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_18,Response_reg
IHAFMDNN_01165	585394.RHOM_08005	8.35e-107	319.0	COG1406@1|root,COG1406@2|Bacteria,1V46M@1239|Firmicutes,24B3C@186801|Clostridia	186801|Clostridia	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
IHAFMDNN_01166	622312.ROSEINA2194_03854	2.51e-310	852.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
IHAFMDNN_01167	585394.RHOM_08020	3.18e-127	369.0	28NT4@1|root,2ZBRW@2|Bacteria,1UXVI@1239|Firmicutes,24ABY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01168	585394.RHOM_11975	5.31e-109	339.0	28PI9@1|root,2ZC8C@2|Bacteria,1V6ZI@1239|Firmicutes,24M4V@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
IHAFMDNN_01169	632245.CLP_3145	5.77e-97	293.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,36E6F@31979|Clostridiaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
IHAFMDNN_01170	457412.RSAG_01452	6e-245	682.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01171	411469.EUBHAL_00026	0.0	978.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
IHAFMDNN_01172	585394.RHOM_09115	7.22e-138	401.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
IHAFMDNN_01173	585394.RHOM_08560	2.83e-162	454.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
IHAFMDNN_01174	585394.RHOM_08565	3.45e-115	355.0	COG1033@1|root,COG1033@2|Bacteria,1VIN4@1239|Firmicutes	1239|Firmicutes	S	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
IHAFMDNN_01175	622312.ROSEINA2194_01774	1.73e-151	448.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
IHAFMDNN_01176	585394.RHOM_09275	0.0	904.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia	186801|Clostridia	N	-transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
IHAFMDNN_01177	585394.RHOM_09280	2.46e-144	416.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01178	585394.RHOM_09285	2.8e-67	211.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
IHAFMDNN_01179	33035.JPJF01000028_gene2808	1.69e-126	364.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
IHAFMDNN_01180	585394.RHOM_14780	0.0	1229.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
IHAFMDNN_01181	585394.RHOM_14775	2.08e-130	375.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
IHAFMDNN_01182	397291.C804_05622	2.26e-57	187.0	COG0745@1|root,COG0745@2|Bacteria,1V566@1239|Firmicutes,25EMQ@186801|Clostridia,27TZD@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
IHAFMDNN_01183	1280682.AUKA01000005_gene2643	4.64e-135	426.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,4BWTF@830|Butyrivibrio	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MASE3,Response_reg
IHAFMDNN_01185	622312.ROSEINA2194_00266	1.38e-37	127.0	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01186	585394.RHOM_03105	5.39e-57	187.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V1DC@1239|Firmicutes,24GJV@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
IHAFMDNN_01187	585394.RHOM_03100	1.38e-216	614.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
IHAFMDNN_01188	585394.RHOM_03095	2.18e-60	191.0	2CPN3@1|root,32SJG@2|Bacteria,1VASE@1239|Firmicutes,24KG6@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
IHAFMDNN_01189	585394.RHOM_03090	3.83e-267	736.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
IHAFMDNN_01190	1226325.HMPREF1548_06783	1.2e-131	377.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_01191	1408312.JNJS01000004_gene2495	3.44e-103	306.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
IHAFMDNN_01192	585394.RHOM_07815	0.0	928.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia	186801|Clostridia	D	FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
IHAFMDNN_01193	585394.RHOM_00105	9.32e-179	505.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
IHAFMDNN_01194	622312.ROSEINA2194_03243	1.16e-119	343.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
IHAFMDNN_01195	585394.RHOM_00065	6.49e-169	475.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
IHAFMDNN_01196	622312.ROSEINA2194_03241	9.97e-127	374.0	COG0840@1|root,COG4905@1|root,COG0840@2|Bacteria,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
IHAFMDNN_01197	585394.RHOM_05145	0.0	2249.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
IHAFMDNN_01198	585394.RHOM_12625	1.86e-100	293.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia	186801|Clostridia	H	Dipicolinic acid synthetase, b subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
IHAFMDNN_01199	585394.RHOM_12620	2.17e-52	165.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
IHAFMDNN_01200	585394.RHOM_12615	0.0	1536.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
IHAFMDNN_01201	585394.RHOM_13120	2.53e-53	171.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
IHAFMDNN_01202	585394.RHOM_13125	1.6e-146	416.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia	186801|Clostridia	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
IHAFMDNN_01203	622312.ROSEINA2194_02141	1.09e-254	708.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IHAFMDNN_01204	622312.ROSEINA2194_02142	1.07e-145	418.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
IHAFMDNN_01205	585394.RHOM_07850	2.87e-175	510.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
IHAFMDNN_01206	622312.ROSEINA2194_03813	1.54e-212	595.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
IHAFMDNN_01207	585394.RHOM_07845	2.16e-70	213.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
IHAFMDNN_01208	585394.RHOM_08105	1.38e-18	80.1	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
IHAFMDNN_01209	585394.RHOM_08100	2.92e-34	117.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
IHAFMDNN_01210	622312.ROSEINA2194_01009	1.33e-70	213.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
IHAFMDNN_01211	1226325.HMPREF1548_04834	1.86e-09	59.3	COG0613@1|root,COG0613@2|Bacteria,1V33M@1239|Firmicutes,24H1U@186801|Clostridia,36M9R@31979|Clostridiaceae	186801|Clostridia	S	PHP-associated	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
IHAFMDNN_01212	585394.RHOM_08535	5.12e-75	231.0	COG0613@1|root,COG0613@2|Bacteria,1V33M@1239|Firmicutes,24H1U@186801|Clostridia	186801|Clostridia	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
IHAFMDNN_01213	585394.RHOM_08530	3.55e-173	486.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
IHAFMDNN_01214	622312.ROSEINA2194_03681	2.31e-234	645.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
IHAFMDNN_01215	585394.RHOM_08120	8.52e-146	417.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia	186801|Clostridia	S	PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
IHAFMDNN_01216	585394.RHOM_08125	3.83e-130	376.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IHAFMDNN_01217	585394.RHOM_08130	0.0	1080.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia	186801|Clostridia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
IHAFMDNN_01218	585394.RHOM_08735	4.36e-249	697.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
IHAFMDNN_01219	585394.RHOM_08730	2.7e-140	413.0	COG2244@1|root,COG2244@2|Bacteria,1V0I3@1239|Firmicutes,24F2V@186801|Clostridia	186801|Clostridia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
IHAFMDNN_01220	622312.ROSEINA2194_04026	1.88e-104	307.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
IHAFMDNN_01221	585394.RHOM_14175	1.5e-232	641.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
IHAFMDNN_01222	585394.RHOM_14180	0.0	1026.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IHAFMDNN_01223	585394.RHOM_11425	0.0	1391.0	COG1482@1|root,COG2723@1|root,COG1482@2|Bacteria,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1,PMI_typeI
IHAFMDNN_01224	585394.RHOM_11430	2.31e-176	502.0	COG2755@1|root,COG2755@2|Bacteria,1TQG2@1239|Firmicutes,24A1G@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IHAFMDNN_01225	585394.RHOM_07675	4.91e-118	345.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,ParA
IHAFMDNN_01226	585394.RHOM_07685	0.0	1337.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
IHAFMDNN_01227	1232452.BAIB02000011_gene2128	2.61e-32	116.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,268UD@186813|unclassified Clostridiales	186801|Clostridia	T	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
IHAFMDNN_01228	585394.RHOM_03400	1.17e-101	302.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
IHAFMDNN_01229	622312.ROSEINA2194_02476	1.41e-105	313.0	COG1011@1|root,COG1011@2|Bacteria,1UIG9@1239|Firmicutes,25EMR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
IHAFMDNN_01230	585394.RHOM_03410	5.39e-59	200.0	COG3064@1|root,COG3064@2|Bacteria,1V52J@1239|Firmicutes,24HMZ@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01231	140626.JHWB01000009_gene1219	2.28e-27	100.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
IHAFMDNN_01232	585394.RHOM_00945	3.44e-117	335.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
IHAFMDNN_01233	397290.C810_03360	9.01e-89	261.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,27M6H@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
IHAFMDNN_01234	622312.ROSEINA2194_01982	7.27e-157	441.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
IHAFMDNN_01235	585394.RHOM_00960	7.98e-105	305.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
IHAFMDNN_01236	585394.RHOM_00965	1.57e-70	214.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
IHAFMDNN_01237	585394.RHOM_11950	0.0	1030.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
IHAFMDNN_01238	585394.RHOM_11945	7.2e-33	114.0	2E96G@1|root,333F2@2|Bacteria,1VHVR@1239|Firmicutes,24SE5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01239	585394.RHOM_11940	0.0	920.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
IHAFMDNN_01240	622312.ROSEINA2194_02504	5.44e-152	436.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
IHAFMDNN_01241	585394.RHOM_11930	3.18e-302	828.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
IHAFMDNN_01242	585394.RHOM_11925	3.63e-187	530.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
IHAFMDNN_01243	585394.RHOM_11920	7.28e-160	456.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase, group 2 family protein	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
IHAFMDNN_01244	585394.RHOM_11910	3.31e-175	505.0	2DSN8@1|root,33GRU@2|Bacteria,1VPDR@1239|Firmicutes,24PGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01245	585394.RHOM_11905	1.21e-204	585.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
IHAFMDNN_01246	1408323.JQKK01000003_gene2632	2.1e-184	528.0	COG0603@1|root,COG0603@2|Bacteria,1V0EU@1239|Firmicutes,24BK5@186801|Clostridia,27KYX@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01247	1410628.JNKS01000072_gene1060	3.18e-159	460.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,27IMU@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
IHAFMDNN_01248	585394.RHOM_11815	9.85e-284	779.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia	186801|Clostridia	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
IHAFMDNN_01249	585394.RHOM_11810	6.91e-298	814.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
IHAFMDNN_01250	585394.RHOM_11800	6.68e-90	269.0	2BYUV@1|root,307Y4@2|Bacteria,1V64G@1239|Firmicutes,24K9A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01251	888832.HMPREF9420_0119	2.2e-35	123.0	COG4545@1|root,COG4545@2|Bacteria,4P47F@976|Bacteroidetes,2FU4N@200643|Bacteroidia	976|Bacteroidetes	O	Glutaredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
IHAFMDNN_01252	658088.HMPREF0987_02092	0.0	1103.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,27J10@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_01253	658088.HMPREF0987_02093	6.2e-100	303.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,27IIX@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
IHAFMDNN_01254	585394.RHOM_08335	5.34e-156	441.0	COG1036@1|root,COG2878@1|root,COG1036@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
IHAFMDNN_01255	585394.RHOM_08340	4.83e-123	352.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
IHAFMDNN_01256	585394.RHOM_08345	9.91e-139	395.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
IHAFMDNN_01257	585394.RHOM_08350	3.91e-106	310.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
IHAFMDNN_01258	585394.RHOM_08355	1.52e-185	520.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
IHAFMDNN_01259	585394.RHOM_00275	1.76e-153	436.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IHAFMDNN_01261	411459.RUMOBE_02700	2.89e-95	281.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,3Y18Q@572511|Blautia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IHAFMDNN_01262	411459.RUMOBE_02699	8.21e-219	605.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3XYUJ@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
IHAFMDNN_01263	411459.RUMOBE_02698	2.78e-126	363.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
IHAFMDNN_01264	411459.RUMOBE_02697	3.11e-270	741.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3Y0YH@572511|Blautia	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IHAFMDNN_01265	1408323.JQKK01000024_gene1322	1.28e-09	55.8	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24UJT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01266	585394.RHOM_00305	0.0	1206.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
IHAFMDNN_01267	585394.RHOM_00310	3.65e-196	551.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,POR
IHAFMDNN_01268	203119.Cthe_3129	1.25e-140	411.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
IHAFMDNN_01269	585394.RHOM_00325	1.01e-128	375.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
IHAFMDNN_01270	585394.RHOM_00355	9.47e-45	156.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
IHAFMDNN_01271	585394.RHOM_00370	2.49e-109	320.0	COG2357@1|root,COG2357@2|Bacteria,1VDTE@1239|Firmicutes,24Q2S@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
IHAFMDNN_01272	622312.ROSEINA2194_04395	2.86e-143	414.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
IHAFMDNN_01273	622312.ROSEINA2194_04397	1e-160	455.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IHAFMDNN_01274	622312.ROSEINA2194_04398	7.24e-155	440.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia	186801|Clostridia	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
IHAFMDNN_01275	622312.ROSEINA2194_04399	5.18e-171	478.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
IHAFMDNN_01276	585394.RHOM_00395	3.7e-116	337.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
IHAFMDNN_01277	1235790.C805_03392	5.65e-22	88.2	2EIA7@1|root,33C1J@2|Bacteria,1VMCK@1239|Firmicutes,24W47@186801|Clostridia,25XQS@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF2508)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2508
IHAFMDNN_01278	585394.RHOM_15815	2.02e-68	211.0	COG1516@1|root,COG1516@2|Bacteria,1VD1Q@1239|Firmicutes,24PMH@186801|Clostridia	186801|Clostridia	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
IHAFMDNN_01279	585394.RHOM_15820	3.76e-200	572.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
IHAFMDNN_01280	585394.RHOM_15825	7.4e-41	134.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia	186801|Clostridia	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
IHAFMDNN_01281	585394.RHOM_15830	9.65e-127	367.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
IHAFMDNN_01282	457412.RSAG_02071	1.31e-206	596.0	COG1874@1|root,COG1874@2|Bacteria,1UZRC@1239|Firmicutes,24EDS@186801|Clostridia	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01283	658086.HMPREF0994_01029	5.86e-246	709.0	28I74@1|root,2Z8A0@2|Bacteria,1VR23@1239|Firmicutes	1239|Firmicutes	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01284	397291.C804_02929	0.0	1613.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,27KWU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
IHAFMDNN_01285	1128421.JAGA01000003_gene2954	5.02e-31	131.0	COG2211@1|root,COG2211@2|Bacteria,2NR8E@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IHAFMDNN_01286	1195236.CTER_1937	3.81e-262	750.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_01287	658086.HMPREF0994_03950	2.35e-207	599.0	COG3525@1|root,COG3525@2|Bacteria,1TSXM@1239|Firmicutes,248U1@186801|Clostridia,27QES@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
IHAFMDNN_01288	622312.ROSEINA2194_03990	2.21e-102	299.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
IHAFMDNN_01289	622312.ROSEINA2194_03989	1.65e-167	478.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
IHAFMDNN_01290	622312.ROSEINA2194_03988	4.19e-138	419.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
IHAFMDNN_01291	585394.RHOM_13095	4.32e-80	239.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia	186801|Clostridia	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
IHAFMDNN_01292	585394.RHOM_13085	1.04e-211	584.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
IHAFMDNN_01293	622312.ROSEINA2194_02128	2.8e-76	234.0	COG0344@1|root,COG0344@2|Bacteria,1V798@1239|Firmicutes,24KR2@186801|Clostridia	186801|Clostridia	I	Belongs to the PlsY family	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
IHAFMDNN_01294	622312.ROSEINA2194_02127	8.78e-177	503.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
IHAFMDNN_01295	585394.RHOM_09720	9.44e-187	522.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01296	585394.RHOM_09725	5.37e-57	179.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
IHAFMDNN_01297	622312.ROSEINA2194_00078	7.63e-204	568.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
IHAFMDNN_01298	633697.EubceDRAFT1_0116	5.32e-117	337.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
IHAFMDNN_01299	622312.ROSEINA2194_02469	2.72e-51	162.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01300	622312.ROSEINA2194_02470	2.04e-131	380.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
IHAFMDNN_01301	585394.RHOM_03615	3.35e-220	608.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
IHAFMDNN_01302	585394.RHOM_06750	4.16e-313	855.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia	186801|Clostridia	C	'glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
IHAFMDNN_01303	622312.ROSEINA2194_00370	9.43e-202	559.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia	186801|Clostridia	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
IHAFMDNN_01304	585394.RHOM_06740	5.41e-162	457.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
IHAFMDNN_01305	622312.ROSEINA2194_03605	2.77e-160	450.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01306	585394.RHOM_15945	9.72e-122	357.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01307	411489.CLOL250_02558	1.97e-32	113.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7
IHAFMDNN_01308	1235790.C805_03449	2.66e-59	184.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
IHAFMDNN_01309	1232453.BAIF02000049_gene828	5e-15	70.1	2ENA7@1|root,33FXX@2|Bacteria,1VMBP@1239|Firmicutes,24USY@186801|Clostridia,26CD2@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01310	1449050.JNLE01000005_gene4440	2.33e-113	344.0	COG0727@1|root,COG0727@2|Bacteria,1UZ5G@1239|Firmicutes,25GD9@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
IHAFMDNN_01311	585394.RHOM_06120	0.0	921.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
IHAFMDNN_01312	585394.RHOM_06110	2.38e-254	706.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01313	585394.RHOM_06105	4.28e-155	444.0	COG0760@1|root,COG0760@2|Bacteria,1V8DP@1239|Firmicutes,24F9F@186801|Clostridia	186801|Clostridia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
IHAFMDNN_01314	585394.RHOM_06100	0.0	883.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
IHAFMDNN_01315	397290.C810_03072	2.71e-37	127.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,27P0I@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01316	622312.ROSEINA2194_01555	1.6e-103	304.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
IHAFMDNN_01317	585394.RHOM_06085	0.0	1506.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
IHAFMDNN_01318	622312.ROSEINA2194_01559	0.0	1481.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
IHAFMDNN_01320	713605.ADHG01000006_gene763	3.2e-72	221.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,4ISAD@91061|Bacilli,3FBRT@33958|Lactobacillaceae	91061|Bacilli	J	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IHAFMDNN_01321	1235802.C823_04091	2.49e-133	384.0	COG3755@1|root,COG3755@2|Bacteria,1VHSS@1239|Firmicutes,24U0W@186801|Clostridia	186801|Clostridia	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
IHAFMDNN_01323	622312.ROSEINA2194_01222	9.54e-52	172.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
IHAFMDNN_01324	622312.ROSEINA2194_01221	1.15e-95	288.0	28ZIG@1|root,2ZM9W@2|Bacteria,1V2JN@1239|Firmicutes,25BHX@186801|Clostridia	186801|Clostridia	S	SpoIIIAH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIIAH
IHAFMDNN_01325	585394.RHOM_08965	1.88e-255	703.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
IHAFMDNN_01326	622312.ROSEINA2194_02860	1.55e-126	378.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia	186801|Clostridia	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
IHAFMDNN_01327	585394.RHOM_11380	2.17e-235	656.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
IHAFMDNN_01328	585394.RHOM_11385	5.98e-77	233.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01329	622312.ROSEINA2194_02871	4.53e-41	135.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
IHAFMDNN_01330	585394.RHOM_06570	1.96e-27	108.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
IHAFMDNN_01331	622312.ROSEINA2194_01198	1.23e-206	576.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
IHAFMDNN_01332	585394.RHOM_06580	3.17e-219	607.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
IHAFMDNN_01333	585394.RHOM_06585	1.92e-79	242.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
IHAFMDNN_01335	585394.RHOM_05605	7.47e-143	418.0	COG2182@1|root,COG2182@2|Bacteria,1V0VV@1239|Firmicutes,24E7F@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
IHAFMDNN_01336	585394.RHOM_05600	3.02e-246	681.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
IHAFMDNN_01337	585394.RHOM_05595	1.95e-195	544.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
IHAFMDNN_01338	585394.RHOM_08395	8.75e-193	538.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
IHAFMDNN_01339	622312.ROSEINA2194_00502	7.33e-223	623.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
IHAFMDNN_01340	585394.RHOM_08385	1.23e-127	366.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
IHAFMDNN_01341	585394.RHOM_11435	7.12e-182	514.0	COG2755@1|root,COG2755@2|Bacteria,1TS75@1239|Firmicutes,24DPZ@186801|Clostridia	186801|Clostridia	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IHAFMDNN_01342	585394.RHOM_11440	1.27e-248	682.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
IHAFMDNN_01343	585394.RHOM_11445	5.55e-235	649.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,24A1K@186801|Clostridia	186801|Clostridia	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
IHAFMDNN_01344	411489.CLOL250_01927	2.58e-254	709.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,36EFF@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
IHAFMDNN_01345	411469.EUBHAL_01800	1.2e-42	153.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,25V8F@186806|Eubacteriaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
IHAFMDNN_01346	515620.EUBELI_20602	1.2e-51	164.0	2CG7V@1|root,32S3C@2|Bacteria,1UIG6@1239|Firmicutes,25EMK@186801|Clostridia,25ZVA@186806|Eubacteriaceae	186801|Clostridia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4298,Dabb
IHAFMDNN_01347	515620.EUBELI_20270	3.85e-86	256.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,25W9B@186806|Eubacteriaceae	186801|Clostridia	S	Aminoacyl-tRNA editing domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
IHAFMDNN_01348	585394.RHOM_08055	0.0	1598.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
IHAFMDNN_01349	585394.RHOM_06150	0.0	902.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
IHAFMDNN_01350	1226325.HMPREF1548_02216	4.1e-120	348.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,36F9G@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
IHAFMDNN_01351	1123075.AUDP01000001_gene2395	2.56e-96	287.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
IHAFMDNN_01353	585394.RHOM_07755	8.91e-110	334.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	-
IHAFMDNN_01354	585394.RHOM_07760	7.05e-207	576.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
IHAFMDNN_01355	585394.RHOM_07765	5.69e-116	348.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia	186801|Clostridia	S	Sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
IHAFMDNN_01356	622312.ROSEINA2194_01022	5.01e-44	155.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,24F7N@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator	bltR	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
IHAFMDNN_01357	411461.DORFOR_00949	4.46e-28	110.0	2CJI5@1|root,32SA3@2|Bacteria,1VAH5@1239|Firmicutes,24MTX@186801|Clostridia,27VSK@189330|Dorea	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
IHAFMDNN_01359	585394.RHOM_13920	1.47e-260	726.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
IHAFMDNN_01360	445973.CLOBAR_00478	1.52e-269	747.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,25RRQ@186804|Peptostreptococcaceae	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
IHAFMDNN_01361	742733.HMPREF9469_01638	9.34e-64	201.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,220IG@1506553|Lachnoclostridium	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
IHAFMDNN_01362	742738.HMPREF9460_00250	1.76e-13	68.9	arCOG04966@1|root,33EHA@2|Bacteria,1VN4X@1239|Firmicutes,24VEA@186801|Clostridia,26C56@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01363	1410616.JHXE01000014_gene390	1.33e-139	403.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,24KGS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_01364	622312.ROSEINA2194_01023	3.1e-174	501.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01365	585394.RHOM_13940	1.9e-85	253.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia	186801|Clostridia	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
IHAFMDNN_01367	622312.ROSEINA2194_00803	4.57e-71	226.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
IHAFMDNN_01368	622312.ROSEINA2194_03332	8.02e-58	198.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
IHAFMDNN_01369	622312.ROSEINA2194_00581	7.97e-37	129.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01371	585394.RHOM_03740	3.25e-190	534.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia	186801|Clostridia	I	stage v sporulation protein ad	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
IHAFMDNN_01372	622312.ROSEINA2194_00584	1.28e-68	208.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
IHAFMDNN_01373	622312.ROSEINA2194_00350	4.25e-62	191.0	COG0537@1|root,COG0537@2|Bacteria,1V3BE@1239|Firmicutes,24H73@186801|Clostridia	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HIT
IHAFMDNN_01374	585394.RHOM_00055	1.39e-68	209.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
IHAFMDNN_01375	585394.RHOM_00050	3e-172	484.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
IHAFMDNN_01376	585394.RHOM_00045	6.66e-175	490.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
IHAFMDNN_01377	585394.RHOM_00040	2.12e-109	325.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia	186801|Clostridia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
IHAFMDNN_01378	658086.HMPREF0994_06595	0.0	1186.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27JWP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_01379	742740.HMPREF9474_01564	7.2e-53	171.0	2AH77@1|root,317H3@2|Bacteria,1V6I2@1239|Firmicutes,24KDW@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
IHAFMDNN_01380	1123075.AUDP01000012_gene3562	8.46e-53	171.0	COG3279@1|root,COG3279@2|Bacteria,1VEPW@1239|Firmicutes,24K2U@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
IHAFMDNN_01381	1280692.AUJL01000002_gene2728	7.37e-85	280.0	COG1132@1|root,COG1132@2|Bacteria,1V2WX@1239|Firmicutes,24GV7@186801|Clostridia,36R7T@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01383	537007.BLAHAN_05724	2e-156	450.0	COG3550@1|root,COG3550@2|Bacteria,1UYFT@1239|Firmicutes,24C8G@186801|Clostridia,3Y2EV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01384	585394.RHOM_00030	0.0	1509.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IHAFMDNN_01385	585394.RHOM_00025	0.0	1207.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IHAFMDNN_01386	622312.ROSEINA2194_03238	1.84e-215	600.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
IHAFMDNN_01387	585394.RHOM_00015	1.54e-34	119.0	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
IHAFMDNN_01388	585394.RHOM_04225	1.45e-297	813.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
IHAFMDNN_01389	585394.RHOM_04220	9.79e-119	342.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
IHAFMDNN_01390	585394.RHOM_04215	2.74e-223	618.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
IHAFMDNN_01391	585394.RHOM_04210	2.13e-48	157.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
IHAFMDNN_01392	622312.ROSEINA2194_01509	1.46e-285	796.0	COG0366@1|root,COG0366@2|Bacteria,1TSEA@1239|Firmicutes,248HJ@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
IHAFMDNN_01393	585394.RHOM_12765	1.82e-77	238.0	2E401@1|root,32YWY@2|Bacteria,1V9X1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01394	1449335.JQLG01000004_gene941	4e-17	79.0	COG1309@1|root,COG1309@2|Bacteria,1VGKF@1239|Firmicutes,4HQGM@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IHAFMDNN_01395	140626.JHWB01000016_gene2464	1.13e-46	152.0	2E11F@1|root,32WHB@2|Bacteria,1VD34@1239|Firmicutes,24NEB@186801|Clostridia	186801|Clostridia	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
IHAFMDNN_01396	585394.RHOM_07945	7.97e-229	632.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
IHAFMDNN_01397	1256908.HMPREF0373_02472	0.0	916.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
IHAFMDNN_01398	585394.RHOM_03825	1.69e-280	778.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
IHAFMDNN_01400	622312.ROSEINA2194_00348	5.11e-155	439.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
IHAFMDNN_01401	585394.RHOM_13110	1.97e-230	651.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
IHAFMDNN_01402	585394.RHOM_13115	1.26e-46	150.0	COG4466@1|root,COG4466@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
IHAFMDNN_01403	585394.RHOM_03320	0.0	1521.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
IHAFMDNN_01404	515620.EUBELI_00158	1.19e-161	456.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V2SW@1239|Firmicutes,24GTR@186801|Clostridia,25XBA@186806|Eubacteriaceae	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
IHAFMDNN_01405	397291.C804_02928	2.22e-217	602.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,27JZU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
IHAFMDNN_01406	1280676.AUJO01000002_gene1478	5.44e-257	716.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,4BYV9@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1,SBP_bac_8
IHAFMDNN_01407	1280676.AUJO01000002_gene1479	4.85e-167	471.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,4C1Y7@830|Butyrivibrio	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_01408	411469.EUBHAL_01060	5.17e-59	192.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,25VC0@186806|Eubacteriaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
IHAFMDNN_01409	411489.CLOL250_01423	6.86e-235	652.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,36EF4@31979|Clostridiaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
IHAFMDNN_01410	411489.CLOL250_01422	6.32e-05	43.5	2EMZ1@1|root,33FM6@2|Bacteria,1VMDZ@1239|Firmicutes,24X8Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01411	1504823.CCMM01000008_gene907	2.57e-153	438.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	yeiI	-	2.7.1.15,2.7.1.45,2.7.1.83	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	M00061,M00308,M00631	R01051,R01541,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,PfkB
IHAFMDNN_01412	585394.RHOM_02825	2.13e-76	239.0	COG5523@1|root,COG5523@2|Bacteria,1VB3B@1239|Firmicutes,24N6Q@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
IHAFMDNN_01413	585394.RHOM_02820	4.11e-296	813.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia	186801|Clostridia	F	permease	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
IHAFMDNN_01414	585394.RHOM_02815	1.51e-69	219.0	COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,24A1Z@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
IHAFMDNN_01415	397291.C804_04826	3.21e-193	540.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,24YP3@186801|Clostridia,27KGJ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_01416	397291.C804_04825	0.0	989.0	COG1653@1|root,COG1653@2|Bacteria,1TQWF@1239|Firmicutes,24CWD@186801|Clostridia,27IIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
IHAFMDNN_01417	585394.RHOM_04205	0.0	984.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
IHAFMDNN_01418	585394.RHOM_04200	3.65e-114	330.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
IHAFMDNN_01419	622312.ROSEINA2194_02252	1.03e-38	132.0	2ETB0@1|root,33KUX@2|Bacteria,1VPRN@1239|Firmicutes,24WSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01421	665950.HMPREF1025_00892	1.45e-121	360.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,27IYF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
IHAFMDNN_01423	411459.RUMOBE_02766	1.77e-198	550.0	COG1512@1|root,COG1512@2|Bacteria	2|Bacteria	S	TPM domain	ycfZ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.24.3	ko:K01387,ko:K06872	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	TPM_phosphatase
IHAFMDNN_01424	411459.RUMOBE_02765	1.09e-256	703.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01425	411459.RUMOBE_02764	2.76e-270	741.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3Y16V@572511|Blautia	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
IHAFMDNN_01426	585394.RHOM_07420	4.53e-57	181.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
IHAFMDNN_01427	622312.ROSEINA2194_03704	1.28e-202	570.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
IHAFMDNN_01428	585394.RHOM_07430	4.38e-142	402.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
IHAFMDNN_01429	483218.BACPEC_01205	1.14e-169	478.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,269QP@186813|unclassified Clostridiales	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	-	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_7,NIR_SIR,NIR_SIR_ferr
IHAFMDNN_01430	483218.BACPEC_01204	6.62e-46	149.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
IHAFMDNN_01431	483218.BACPEC_01203	1.81e-42	141.0	COG0526@1|root,COG0526@2|Bacteria,1UHN6@1239|Firmicutes,25FT1@186801|Clostridia	186801|Clostridia	O	Thioredoxin	trxA1	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IHAFMDNN_01432	483218.BACPEC_01202	2.65e-29	105.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia	186801|Clostridia	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
IHAFMDNN_01433	483218.BACPEC_01201	4.81e-183	510.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,269P8@186813|unclassified Clostridiales	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
IHAFMDNN_01434	1160721.RBI_I01804	4.61e-57	181.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
IHAFMDNN_01435	180332.JTGN01000013_gene974	8.34e-33	146.0	COG2340@1|root,COG3087@1|root,COG3507@1|root,COG3533@1|root,COG2340@2|Bacteria,COG3087@2|Bacteria,COG3507@2|Bacteria,COG3533@2|Bacteria,1TRV9@1239|Firmicutes,24CKP@186801|Clostridia	186801|Clostridia	G	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
IHAFMDNN_01436	1449050.JNLE01000003_gene2095	1.5e-15	90.9	COG0304@1|root,COG2273@1|root,COG2340@1|root,COG3291@1|root,COG0304@2|Bacteria,COG2273@2|Bacteria,COG2340@2|Bacteria,COG3291@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,36HJG@31979|Clostridiaceae	186801|Clostridia	G	family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,DUF1533,Glyco_hydro_16,SLH
IHAFMDNN_01437	483218.BACPEC_00641	8.69e-114	333.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia,26CP4@186813|unclassified Clostridiales	186801|Clostridia	K	TipAS antibiotic-recognition domain	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
IHAFMDNN_01439	1408312.JNJS01000004_gene2495	7.95e-149	425.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
IHAFMDNN_01440	622312.ROSEINA2194_00812	4.47e-35	120.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
IHAFMDNN_01441	585394.RHOM_14080	3.03e-180	507.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
IHAFMDNN_01442	622312.ROSEINA2194_00810	1.33e-151	435.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia	186801|Clostridia	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
IHAFMDNN_01443	476272.RUMHYD_01858	2.15e-115	337.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
IHAFMDNN_01444	585394.RHOM_14065	5.26e-243	674.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
IHAFMDNN_01445	622312.ROSEINA2194_00807	4.38e-80	239.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
IHAFMDNN_01446	742722.HMPREF9463_01777	4.22e-18	79.3	COG1669@1|root,COG1669@2|Bacteria,2HVIG@201174|Actinobacteria,4CWW6@84998|Coriobacteriia	84998|Coriobacteriia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
IHAFMDNN_01448	585394.RHOM_16105	4.21e-79	244.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
IHAFMDNN_01449	585394.RHOM_16615	4.91e-301	823.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
IHAFMDNN_01450	585394.RHOM_16620	3.14e-33	118.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
IHAFMDNN_01451	1123405.AUMM01000022_gene1917	3.99e-29	122.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,4HFJ0@91061|Bacilli,26P0S@186821|Sporolactobacillaceae	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	gspK	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
IHAFMDNN_01452	140626.JHWB01000009_gene1454	4.79e-117	341.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
IHAFMDNN_01453	1280664.AUIX01000021_gene2964	3.78e-170	487.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,4BX6M@830|Butyrivibrio	186801|Clostridia	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IHAFMDNN_01454	397291.C804_03441	9.42e-72	220.0	COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,24G1R@186801|Clostridia,27MWM@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
IHAFMDNN_01455	585394.RHOM_02805	8.84e-169	475.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
IHAFMDNN_01456	585394.RHOM_02800	1.47e-214	598.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
IHAFMDNN_01458	585394.RHOM_10590	8.73e-36	123.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
IHAFMDNN_01459	1304866.K413DRAFT_2073	9.95e-66	204.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,36IEH@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
IHAFMDNN_01460	1235799.C818_03332	7.94e-17	72.4	2C6KI@1|root,33J10@2|Bacteria,1VKBK@1239|Firmicutes,24UUY@186801|Clostridia,27Q8P@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
IHAFMDNN_01461	585394.RHOM_03455	0.0	1199.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
IHAFMDNN_01462	585394.RHOM_04635	0.0	1139.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
IHAFMDNN_01463	585394.RHOM_04640	6.63e-217	607.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
IHAFMDNN_01464	585394.RHOM_14420	1.44e-122	350.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
IHAFMDNN_01465	585394.RHOM_14445	3.46e-66	204.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SseB
IHAFMDNN_01466	397291.C804_00768	7.92e-185	560.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,27ICQ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
IHAFMDNN_01467	585394.RHOM_00590	2.91e-140	399.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_01468	585394.RHOM_13945	3.53e-263	728.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01469	585394.RHOM_00565	0.0	964.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
IHAFMDNN_01470	585394.RHOM_00560	1.57e-202	582.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,sCache_3_3
IHAFMDNN_01471	622312.ROSEINA2194_00437	5.41e-90	274.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
IHAFMDNN_01472	585394.RHOM_00550	1.48e-71	231.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia	186801|Clostridia	D	stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
IHAFMDNN_01474	585394.RHOM_00540	1.03e-186	521.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
IHAFMDNN_01476	642492.Clole_3044	1.32e-138	429.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
IHAFMDNN_01482	622312.ROSEINA2194_01741	1.28e-103	304.0	COG2755@1|root,COG2755@2|Bacteria,1V3A9@1239|Firmicutes,24FYQ@186801|Clostridia	186801|Clostridia	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IHAFMDNN_01483	585394.RHOM_00450	1.74e-160	469.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01484	585394.RHOM_00445	7.19e-49	159.0	2DPVJ@1|root,333JK@2|Bacteria,1VGI4@1239|Firmicutes,24R70@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
IHAFMDNN_01485	483218.BACPEC_01206	6.9e-234	650.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,2683I@186813|unclassified Clostridiales	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
IHAFMDNN_01486	526218.Sterm_3395	1.84e-142	420.0	COG0534@1|root,COG0534@2|Bacteria,37890@32066|Fusobacteria	32066|Fusobacteria	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01487	1392491.JIAE01000001_gene482	4.54e-23	95.5	COG1846@1|root,COG1846@2|Bacteria,1TTMF@1239|Firmicutes,25MX0@186801|Clostridia,3WMH1@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
IHAFMDNN_01488	622312.ROSEINA2194_03597	3.63e-228	642.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
IHAFMDNN_01489	397288.C806_00845	1.88e-54	172.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,27NDR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HxlR-like helix-turn-helix	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
IHAFMDNN_01490	1235793.C809_01456	5.33e-84	251.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24BKH@186801|Clostridia,27KJP@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
IHAFMDNN_01491	585394.RHOM_13805	1.55e-274	753.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
IHAFMDNN_01492	585394.RHOM_13815	8.98e-209	582.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
IHAFMDNN_01493	585394.RHOM_13820	2.8e-315	859.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
IHAFMDNN_01494	622312.ROSEINA2194_02266	1.3e-59	194.0	2DRS1@1|root,33CTC@2|Bacteria,1VPFR@1239|Firmicutes,24X55@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01496	622312.ROSEINA2194_02264	8.25e-174	488.0	COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,24AH1@186801|Clostridia	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01497	622312.ROSEINA2194_02263	1.93e-67	206.0	COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,24MVE@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
IHAFMDNN_01499	585394.RHOM_13825	2.77e-164	464.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
IHAFMDNN_01500	585394.RHOM_13830	1.45e-133	381.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
IHAFMDNN_01501	931626.Awo_c29210	6.64e-68	221.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_01502	1042156.CXIVA_05830	2.1e-123	367.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,36EU6@31979|Clostridiaceae	186801|Clostridia	P	the current gene model (or a revised gene model) may contain a frame shift	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
IHAFMDNN_01503	411468.CLOSCI_02058	5.26e-131	375.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,21XZN@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
IHAFMDNN_01504	1042156.CXIVA_05850	4.16e-126	370.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,36EBM@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
IHAFMDNN_01505	411462.DORLON_01191	1.64e-115	341.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,25C6Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
IHAFMDNN_01506	1227352.C173_28186	9.51e-57	186.0	COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli,26WB3@186822|Paenibacillaceae	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IHAFMDNN_01507	622312.ROSEINA2194_02683	6.18e-282	777.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
IHAFMDNN_01508	1408323.JQKK01000005_gene154	1.91e-64	202.0	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia,27M51@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01509	1408324.JNJK01000048_gene424	3.57e-09	56.2	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia,27M51@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01510	1121115.AXVN01000100_gene825	4.16e-52	178.0	COG4467@1|root,COG4467@2|Bacteria,1UYI4@1239|Firmicutes,2497B@186801|Clostridia	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
IHAFMDNN_01511	585394.RHOM_16625	0.0	1115.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
IHAFMDNN_01512	622312.ROSEINA2194_04348	1.72e-38	140.0	COG3187@1|root,COG3187@2|Bacteria,1UMA9@1239|Firmicutes,25GDD@186801|Clostridia	186801|Clostridia	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01513	1235793.C809_00094	9.24e-172	486.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,27IAP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IHAFMDNN_01514	742735.HMPREF9467_00252	0.0	908.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,21Z5X@1506553|Lachnoclostridium	186801|Clostridia	G	Glycosyl hydrolase family 36 C-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
IHAFMDNN_01515	1298920.KI911353_gene656	3.01e-276	770.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,21XQ0@1506553|Lachnoclostridium	186801|Clostridia	G	SMART alpha amylase catalytic sub domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
IHAFMDNN_01516	1449050.JNLE01000003_gene575	2.05e-172	488.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IHAFMDNN_01517	1235793.C809_00086	9.88e-162	478.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,27J9G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,Flg_new,Glyco_hydro_32C,Glyco_hydro_32N
IHAFMDNN_01518	1449050.JNLE01000003_gene569	8.13e-47	165.0	COG2182@1|root,COG2182@2|Bacteria,1UIC9@1239|Firmicutes,2499Z@186801|Clostridia,36UQF@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
IHAFMDNN_01519	397291.C804_04832	1.48e-267	828.0	COG3209@1|root,COG3693@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3693@2|Bacteria,COG5492@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27K6N@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate family 9 binding domain-like	-	-	3.2.1.4,3.2.1.8	ko:K01179,ko:K01181	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
IHAFMDNN_01520	411461.DORFOR_02222	6.8e-94	281.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,27VNB@189330|Dorea	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
IHAFMDNN_01521	411489.CLOL250_01723	1.16e-50	169.0	COG0454@1|root,COG0456@2|Bacteria,1V7KF@1239|Firmicutes,24K8S@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
IHAFMDNN_01522	1408436.JHXY01000019_gene1391	1.58e-136	395.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,25W58@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IHAFMDNN_01523	411467.BACCAP_02128	9.91e-88	265.0	28N6T@1|root,2ZBBM@2|Bacteria,1TS9F@1239|Firmicutes,24DPE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01524	397287.C807_02675	1.89e-52	170.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,27NNV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
IHAFMDNN_01525	622312.ROSEINA2194_01287	2.54e-87	257.0	2C3VQ@1|root,2ZQ9I@2|Bacteria,1V3RW@1239|Firmicutes,24HQ0@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4320
IHAFMDNN_01526	622312.ROSEINA2194_01288	4.76e-172	483.0	COG2064@1|root,COG2064@2|Bacteria,1TUMZ@1239|Firmicutes,2495N@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	-
IHAFMDNN_01527	397291.C804_05705	1.52e-181	509.0	COG4965@1|root,COG4965@2|Bacteria,1TS4U@1239|Firmicutes,248K2@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01528	622312.ROSEINA2194_01291	2.05e-128	375.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
IHAFMDNN_01529	585394.RHOM_08370	5.93e-166	466.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia	186801|Clostridia	NT	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
IHAFMDNN_01530	585394.RHOM_08375	1.19e-240	664.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
IHAFMDNN_01531	411469.EUBHAL_02516	7.77e-31	118.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia,25WEJ@186806|Eubacteriaceae	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
IHAFMDNN_01532	585394.RHOM_06140	2.91e-131	407.0	28J8A@1|root,2Z93H@2|Bacteria,1UYEZ@1239|Firmicutes,24AV4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01533	585394.RHOM_06140	4.65e-171	513.0	28J8A@1|root,2Z93H@2|Bacteria,1UYEZ@1239|Firmicutes,24AV4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01534	585394.RHOM_08230	5.51e-205	567.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,24A00@186801|Clostridia	186801|Clostridia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
IHAFMDNN_01535	585394.RHOM_08225	0.0	883.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia	186801|Clostridia	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
IHAFMDNN_01536	585394.RHOM_07615	1.06e-61	196.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
IHAFMDNN_01537	585394.RHOM_07620	1.94e-179	509.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
IHAFMDNN_01538	622312.ROSEINA2194_03750	1.03e-124	361.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
IHAFMDNN_01539	585394.RHOM_07630	3.65e-79	240.0	COG1799@1|root,COG1799@2|Bacteria,1V5NF@1239|Firmicutes,25CNH@186801|Clostridia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
IHAFMDNN_01540	1235800.C819_03126	1.02e-98	290.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,27TME@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
IHAFMDNN_01541	622312.ROSEINA2194_00591	0.0	1212.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia	186801|Clostridia	S	Myosin-crossreactive antigen	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
IHAFMDNN_01542	622312.ROSEINA2194_00905	4.47e-118	346.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
IHAFMDNN_01543	622312.ROSEINA2194_00904	7.5e-149	423.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
IHAFMDNN_01545	1235800.C819_00145	2.89e-07	58.9	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZH@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
IHAFMDNN_01546	411461.DORFOR_02133	2.32e-278	767.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,27WEJ@189330|Dorea	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
IHAFMDNN_01547	622312.ROSEINA2194_00442	4.63e-282	776.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
IHAFMDNN_01548	585394.RHOM_12480	0.0	1221.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
IHAFMDNN_01549	397287.C807_03866	3.51e-57	187.0	28S3E@1|root,2ZEF6@2|Bacteria,1V25C@1239|Firmicutes,24GTH@186801|Clostridia,27KYG@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01550	1034345.CAEM01000003_gene1256	7.26e-20	91.7	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CUE6@84998|Coriobacteriia	84998|Coriobacteriia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Response_reg
IHAFMDNN_01551	585394.RHOM_05525	8.02e-238	656.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
IHAFMDNN_01552	585394.RHOM_09770	6.26e-110	319.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
IHAFMDNN_01553	622312.ROSEINA2194_00571	0.0	1215.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_01554	492774.JQMB01000001_gene5620	6.16e-10	69.7	COG3505@1|root,COG3505@2|Bacteria,1MV1G@1224|Proteobacteria,2TR6N@28211|Alphaproteobacteria,4BAUM@82115|Rhizobiaceae	28211|Alphaproteobacteria	U	Type IV secretory pathway, VirD4	virD4	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
IHAFMDNN_01555	585394.RHOM_04340	7.19e-256	707.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
IHAFMDNN_01556	585394.RHOM_08310	1.01e-244	679.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
IHAFMDNN_01557	622312.ROSEINA2194_00521	1.62e-46	157.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
IHAFMDNN_01558	585394.RHOM_08320	1.5e-31	111.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia	186801|Clostridia	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
IHAFMDNN_01561	1256908.HMPREF0373_01181	2.76e-244	680.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
IHAFMDNN_01562	622312.ROSEINA2194_00357	1.81e-29	106.0	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01563	622312.ROSEINA2194_04149	2.11e-210	599.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
IHAFMDNN_01565	742765.HMPREF9457_01779	8.49e-11	58.9	COG0784@1|root,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
IHAFMDNN_01566	585394.RHOM_06055	1.45e-175	498.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
IHAFMDNN_01567	585394.RHOM_06050	1.63e-169	473.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
IHAFMDNN_01568	585394.RHOM_06045	1.28e-189	530.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
IHAFMDNN_01569	1410612.JNKO01000001_gene2727	7.57e-167	470.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2PTU7@265975|Oribacterium	186801|Clostridia	G	Dehydrogenase E1 component	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
IHAFMDNN_01570	585394.RHOM_06035	8.34e-147	414.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
IHAFMDNN_01571	585394.RHOM_06025	0.0	966.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
IHAFMDNN_01572	585394.RHOM_06020	0.0	915.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
IHAFMDNN_01573	622312.ROSEINA2194_04423	8.18e-101	295.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IHAFMDNN_01574	622312.ROSEINA2194_00711	1.25e-262	721.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
IHAFMDNN_01575	622312.ROSEINA2194_03091	0.0	899.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
IHAFMDNN_01576	585394.RHOM_05195	0.0	893.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
IHAFMDNN_01577	483218.BACPEC_01838	2.02e-37	132.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,26813@186813|unclassified Clostridiales	186801|Clostridia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
IHAFMDNN_01578	622312.ROSEINA2194_02768	1.98e-141	404.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
IHAFMDNN_01579	585394.RHOM_08880	3.32e-132	394.0	COG3103@1|root,COG3103@2|Bacteria,COG4991@2|Bacteria,1USNV@1239|Firmicutes,24DRI@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
IHAFMDNN_01580	585394.RHOM_08700	9.8e-74	237.0	COG1132@1|root,COG1132@2|Bacteria,1TRJF@1239|Firmicutes,249CN@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01581	411469.EUBHAL_02535	1.15e-86	275.0	2DBZW@1|root,2ZC46@2|Bacteria,1V2V4@1239|Firmicutes,24H1D@186801|Clostridia	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
IHAFMDNN_01582	1235802.C823_04319	7.85e-50	163.0	COG0681@1|root,COG0681@2|Bacteria,1VFKY@1239|Firmicutes,24RQG@186801|Clostridia,25XJH@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
IHAFMDNN_01583	1235802.C823_05151	3.65e-72	221.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,25WR7@186806|Eubacteriaceae	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
IHAFMDNN_01584	1235802.C823_03008	5.85e-152	452.0	COG0840@1|root,COG1145@1|root,COG4624@1|root,COG0840@2|Bacteria,COG1145@2|Bacteria,COG4624@2|Bacteria,1TSVR@1239|Firmicutes,248TC@186801|Clostridia,25VKU@186806|Eubacteriaceae	186801|Clostridia	CNT	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,MCPsignal
IHAFMDNN_01585	483218.BACPEC_02992	8.95e-103	323.0	COG0840@1|root,COG0840@2|Bacteria,1TSW1@1239|Firmicutes,24B19@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
IHAFMDNN_01586	411470.RUMGNA_01046	7.49e-187	533.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
IHAFMDNN_01587	585394.RHOM_12650	2.24e-91	281.0	2C69W@1|root,2Z7HR@2|Bacteria,1TQNN@1239|Firmicutes,249G5@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4474)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4474
IHAFMDNN_01588	585394.RHOM_12645	8.79e-136	390.0	COG2908@1|root,COG2908@2|Bacteria,1TT6N@1239|Firmicutes,24A8X@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
IHAFMDNN_01589	585394.RHOM_05560	6.64e-147	420.0	COG1655@1|root,COG1655@2|Bacteria,1V2CM@1239|Firmicutes,25CK4@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
IHAFMDNN_01590	622312.ROSEINA2194_03508	0.0	1064.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia	186801|Clostridia	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
IHAFMDNN_01591	585394.RHOM_12905	1.68e-316	867.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
IHAFMDNN_01592	140626.JHWB01000022_gene2128	2.64e-81	248.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IHAFMDNN_01593	622312.ROSEINA2194_00248	3.24e-261	723.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01594	622312.ROSEINA2194_00247	2.26e-227	634.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
IHAFMDNN_01595	642492.Clole_1528	7.07e-68	234.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,MCPsignal
IHAFMDNN_01597	1280698.AUJS01000065_gene671	1.73e-179	514.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
IHAFMDNN_01598	1280698.AUJS01000065_gene670	0.0	1652.0	COG1196@1|root,COG1196@2|Bacteria,1TPW9@1239|Firmicutes,247V7@186801|Clostridia	186801|Clostridia	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
IHAFMDNN_01599	1280698.AUJS01000065_gene669	6.57e-219	610.0	28HUD@1|root,2Z813@2|Bacteria,1TUFV@1239|Firmicutes,24A4P@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
IHAFMDNN_01600	1280698.AUJS01000065_gene668	1.7e-285	788.0	2CC51@1|root,2Z7IU@2|Bacteria,1TQNI@1239|Firmicutes,24DDD@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
IHAFMDNN_01601	585394.RHOM_05455	1.6e-269	739.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
IHAFMDNN_01602	585394.RHOM_05450	1.21e-219	612.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
IHAFMDNN_01603	585394.RHOM_09365	1.26e-124	381.0	COG0810@1|root,COG0810@2|Bacteria,1UJMR@1239|Firmicutes,251BT@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
IHAFMDNN_01604	585394.RHOM_09370	4.3e-34	118.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
IHAFMDNN_01605	585394.RHOM_09375	8.17e-52	169.0	2AKH0@1|root,31B8X@2|Bacteria,1V6ZY@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
IHAFMDNN_01607	140626.JHWB01000022_gene2045	8.62e-107	315.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IHAFMDNN_01608	411459.RUMOBE_02708	1.92e-97	296.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_01609	622312.ROSEINA2194_03257	1.56e-31	110.0	298S6@1|root,2ZVWG@2|Bacteria,1W22G@1239|Firmicutes,256U8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01610	585394.RHOM_13845	0.0	1162.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IHAFMDNN_01611	658086.HMPREF0994_01172	2.02e-21	90.5	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
IHAFMDNN_01612	1226325.HMPREF1548_02199	2.55e-25	97.4	COG4942@1|root,COG4942@2|Bacteria,1VSWX@1239|Firmicutes	1239|Firmicutes	D	K03657 DNA helicase II ATP-dependent DNA helicase PcrA	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01613	1235800.C819_03424	1.31e-171	491.0	COG0657@1|root,COG0657@2|Bacteria,1VUQV@1239|Firmicutes,250IT@186801|Clostridia,27UKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
IHAFMDNN_01614	585394.RHOM_12675	1.07e-85	259.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
IHAFMDNN_01615	622312.ROSEINA2194_03801	1.95e-95	296.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
IHAFMDNN_01616	622312.ROSEINA2194_03792	2.61e-104	305.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
IHAFMDNN_01619	622312.ROSEINA2194_00699	2.13e-72	223.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
IHAFMDNN_01620	585394.RHOM_03135	2.6e-190	538.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
IHAFMDNN_01621	585394.RHOM_03140	4.62e-86	255.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
IHAFMDNN_01622	585394.RHOM_03145	2.47e-103	301.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
IHAFMDNN_01623	585394.RHOM_03215	3.17e-37	125.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
IHAFMDNN_01624	1408304.JAHA01000019_gene2949	2.24e-08	53.9	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,4BY5W@830|Butyrivibrio	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
IHAFMDNN_01625	515620.EUBELI_00113	1.58e-40	139.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,25XGV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
IHAFMDNN_01626	1410658.JHWI01000034_gene1952	1.26e-177	501.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,3VP1J@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_01627	585394.RHOM_12095	1.09e-188	528.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
IHAFMDNN_01628	397288.C806_01854	5.71e-84	286.0	COG5279@1|root,COG5279@2|Bacteria,1VEK2@1239|Firmicutes,24SMT@186801|Clostridia,27NZA@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Transglut_core
IHAFMDNN_01629	585394.RHOM_12090	2.86e-201	564.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia	186801|Clostridia	D	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
IHAFMDNN_01632	585502.HMPREF0645_0321	5.44e-37	143.0	COG0438@1|root,COG0438@2|Bacteria,4NF89@976|Bacteroidetes,2FMFR@200643|Bacteroidia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01634	877424.ATWC01000003_gene1798	4.18e-23	105.0	COG3274@1|root,COG3274@2|Bacteria,1VFZD@1239|Firmicutes,25D9I@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IHAFMDNN_01635	585394.RHOM_12020	4.37e-59	201.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
IHAFMDNN_01636	180332.JTGN01000001_gene4817	3.01e-95	289.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V2EN@1239|Firmicutes,24GG9@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
IHAFMDNN_01637	1469948.JPNB01000001_gene965	1.06e-307	852.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01638	1469948.JPNB01000001_gene966	0.0	882.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01639	1195236.CTER_3491	3.24e-204	584.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V4UB@1239|Firmicutes,24BJM@186801|Clostridia,3WRKI@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
IHAFMDNN_01640	357809.Cphy_0218	0.0	1189.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,21YQ6@1506553|Lachnoclostridium	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
IHAFMDNN_01641	642492.Clole_1639	3.72e-304	854.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_01642	585394.RHOM_06360	2.82e-270	775.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
IHAFMDNN_01643	585394.RHOM_06365	2.45e-36	127.0	COG2198@1|root,COG2198@2|Bacteria,1VGD4@1239|Firmicutes,25CZI@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
IHAFMDNN_01644	2325.TKV_c09470	1.65e-25	106.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,42GYT@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
IHAFMDNN_01645	585394.RHOM_06375	5.92e-102	296.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
IHAFMDNN_01646	483218.BACPEC_02363	1.54e-293	819.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,268P3@186813|unclassified Clostridiales	186801|Clostridia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
IHAFMDNN_01647	585394.RHOM_06380	1.06e-155	441.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
IHAFMDNN_01648	622312.ROSEINA2194_02781	1.74e-56	181.0	2EF5Q@1|root,338YV@2|Bacteria,1VJS5@1239|Firmicutes,24RWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01649	585394.RHOM_13440	1.53e-159	452.0	28KEH@1|root,2ZA0R@2|Bacteria,1V76J@1239|Firmicutes,24JHU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4300
IHAFMDNN_01650	357276.EL88_03960	0.0	1339.0	COG1061@1|root,COG1061@2|Bacteria,4NECV@976|Bacteroidetes,2FNDP@200643|Bacteroidia,4APGY@815|Bacteroidaceae	976|Bacteroidetes	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
IHAFMDNN_01651	478749.BRYFOR_06633	1.71e-151	429.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
IHAFMDNN_01652	411459.RUMOBE_02060	4.68e-63	196.0	COG1846@1|root,COG1846@2|Bacteria,1V749@1239|Firmicutes,24KYW@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
IHAFMDNN_01653	483218.BACPEC_02515	6.34e-156	454.0	COG1132@1|root,COG1132@2|Bacteria,1TPTK@1239|Firmicutes,249W7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01654	1469948.JPNB01000001_gene792	1.9e-66	212.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,36WXQ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
IHAFMDNN_01655	585394.RHOM_05735	3.61e-302	839.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
IHAFMDNN_01658	585394.RHOM_05035	1.04e-282	794.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
IHAFMDNN_01659	478749.BRYFOR_05625	2.97e-288	814.0	COG1609@1|root,COG1653@1|root,COG1609@2|Bacteria,COG1653@2|Bacteria,1V31R@1239|Firmicutes,249JU@186801|Clostridia	186801|Clostridia	K	solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4,SBP_bac_1,SBP_bac_8
IHAFMDNN_01660	397288.C806_02914	1.8e-36	127.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,27MB2@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
IHAFMDNN_01661	585394.RHOM_02545	6.24e-102	303.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
IHAFMDNN_01662	585394.RHOM_02550	1.31e-158	449.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia	186801|Clostridia	S	S1, RNA binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
IHAFMDNN_01663	585394.RHOM_02555	3.88e-75	225.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
IHAFMDNN_01664	592026.GCWU0000282_001066	1.87e-06	47.8	2EI20@1|root,33BTH@2|Bacteria,1VQF2@1239|Firmicutes	1239|Firmicutes	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
IHAFMDNN_01665	622312.ROSEINA2194_00988	2.43e-148	427.0	COG0726@1|root,COG0726@2|Bacteria,1V1X7@1239|Firmicutes,25B6U@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
IHAFMDNN_01666	622312.ROSEINA2194_00989	1.24e-78	246.0	COG1664@1|root,COG1664@2|Bacteria,1TS93@1239|Firmicutes,24DZX@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
IHAFMDNN_01667	585394.RHOM_07165	2.35e-151	427.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
IHAFMDNN_01668	397288.C806_03378	8.03e-160	475.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27KAK@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_1
IHAFMDNN_01669	622312.ROSEINA2194_02490	2.27e-58	185.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
IHAFMDNN_01670	585394.RHOM_11125	1.61e-44	160.0	2E4NI@1|root,32ZHC@2|Bacteria,1VGQR@1239|Firmicutes,24RYT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01671	585394.RHOM_11120	0.0	897.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia	186801|Clostridia	C	domain protein	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
IHAFMDNN_01672	622312.ROSEINA2194_02774	4.04e-122	365.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_01673	622312.ROSEINA2194_02772	4.64e-193	540.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_C,Ldh_1_N
IHAFMDNN_01674	585394.RHOM_09925	2.16e-300	822.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
IHAFMDNN_01675	585394.RHOM_09930	1.29e-50	161.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
IHAFMDNN_01676	585394.RHOM_09940	3.45e-156	442.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia	186801|Clostridia	J	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
IHAFMDNN_01677	585394.RHOM_09945	0.0	1015.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,249Y7@186801|Clostridia	186801|Clostridia	D	cell division protein FtsA	ftsA	-	-	-	-	-	-	-	-	-	-	-	FtsA,MreB_Mbl
IHAFMDNN_01678	622312.ROSEINA2194_00035	5.28e-91	271.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
IHAFMDNN_01679	585394.RHOM_09955	0.0	1439.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
IHAFMDNN_01680	585394.RHOM_09960	0.0	1065.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia	186801|Clostridia	E	creatinase	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
IHAFMDNN_01681	622312.ROSEINA2194_00032	6.35e-100	290.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
IHAFMDNN_01682	622312.ROSEINA2194_00030	1.12e-278	793.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
IHAFMDNN_01683	585394.RHOM_05040	2.43e-48	172.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
IHAFMDNN_01684	585394.RHOM_08140	1.04e-263	728.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia	186801|Clostridia	E	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
IHAFMDNN_01685	585394.RHOM_08145	4.78e-217	605.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
IHAFMDNN_01686	622312.ROSEINA2194_00998	4.98e-104	315.0	COG0823@1|root,COG0823@2|Bacteria,1V60E@1239|Firmicutes,24I0N@186801|Clostridia	186801|Clostridia	U	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
IHAFMDNN_01687	585394.RHOM_07200	2.25e-143	443.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
IHAFMDNN_01688	622312.ROSEINA2194_00997	0.0	2036.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
IHAFMDNN_01689	585394.RHOM_07195	9.54e-226	625.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
IHAFMDNN_01690	622312.ROSEINA2194_00995	1.41e-190	535.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
IHAFMDNN_01691	585394.RHOM_07185	3.87e-207	580.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
IHAFMDNN_01692	622312.ROSEINA2194_00993	1.79e-148	422.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
IHAFMDNN_01693	585394.RHOM_07175	4.9e-145	412.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
IHAFMDNN_01694	585394.RHOM_07170	1.71e-65	203.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
IHAFMDNN_01695	585394.RHOM_03350	1.05e-214	615.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
IHAFMDNN_01696	585394.RHOM_11515	3.34e-57	183.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
IHAFMDNN_01697	1235800.C819_01897	2.24e-132	379.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,27IBR@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_01698	97138.C820_01583	1.71e-20	93.6	COG5464@1|root,COG5464@2|Bacteria,1UI9X@1239|Firmicutes,25EEV@186801|Clostridia,36UNA@31979|Clostridiaceae	186801|Clostridia	S	Putative transposase, YhgA-like	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01699	1256908.HMPREF0373_01583	3.15e-51	162.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24MWS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
IHAFMDNN_01700	411463.EUBVEN_02075	2.76e-94	278.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
IHAFMDNN_01701	622312.ROSEINA2194_00271	2.46e-121	350.0	COG2176@1|root,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,24ER5@186801|Clostridia	186801|Clostridia	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T,zf-C4_Topoisom
IHAFMDNN_01702	140626.JHWB01000022_gene2109	3.94e-31	110.0	2ERQJ@1|root,33J9V@2|Bacteria,1VQ8Z@1239|Firmicutes,24VCG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01703	622312.ROSEINA2194_00544	1.84e-219	608.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_01704	585394.RHOM_11850	1.14e-19	93.2	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
IHAFMDNN_01705	585394.RHOM_06415	1.88e-288	795.0	2BZA3@1|root,2Z7YV@2|Bacteria,1TSER@1239|Firmicutes,24AF5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01706	1408323.JQKK01000025_gene1380	2.53e-71	226.0	2EN4B@1|root,33FSE@2|Bacteria,1VPF9@1239|Firmicutes,24SXK@186801|Clostridia,27NCJ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tim44,zinc_ribbon_2
IHAFMDNN_01707	585394.RHOM_02610	7.05e-227	627.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
IHAFMDNN_01708	622312.ROSEINA2194_01586	2.34e-46	155.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
IHAFMDNN_01709	622312.ROSEINA2194_01585	6.73e-215	604.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
IHAFMDNN_01710	585394.RHOM_02595	5.47e-134	397.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
IHAFMDNN_01711	622312.ROSEINA2194_01582	1.05e-173	489.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
IHAFMDNN_01712	585394.RHOM_02585	5.81e-139	397.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
IHAFMDNN_01713	585394.RHOM_02580	3.34e-246	677.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
IHAFMDNN_01714	622312.ROSEINA2194_01579	1.09e-142	410.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
IHAFMDNN_01715	585394.RHOM_02575	8.72e-82	251.0	COG1922@1|root,COG1922@2|Bacteria,1V7RM@1239|Firmicutes,24HC8@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
IHAFMDNN_01716	585394.RHOM_14870	0.0	933.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia	186801|Clostridia	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
IHAFMDNN_01717	585394.RHOM_02570	1.64e-159	460.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
IHAFMDNN_01718	585394.RHOM_02280	4.48e-277	768.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia	186801|Clostridia	T	Histidine kinase- DNA gyrase B	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_01719	585394.RHOM_02285	5.2e-156	438.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_01720	658086.HMPREF0994_03374	3.61e-42	147.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,27P4M@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
IHAFMDNN_01721	622312.ROSEINA2194_01858	9.21e-140	405.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
IHAFMDNN_01722	689781.AUJX01000003_gene2930	3.8e-80	241.0	COG3467@1|root,COG3467@2|Bacteria,1V6NS@1239|Firmicutes,24JA3@186801|Clostridia,2PSHU@265975|Oribacterium	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	nimA	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
IHAFMDNN_01723	622312.ROSEINA2194_02722	7.14e-30	111.0	2EKR7@1|root,33EEZ@2|Bacteria,1VQ0F@1239|Firmicutes,24UDN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01724	585394.RHOM_08610	6.28e-69	214.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
IHAFMDNN_01725	585394.RHOM_08605	5.31e-158	457.0	COG4641@1|root,COG4641@2|Bacteria,1V642@1239|Firmicutes,24IV8@186801|Clostridia	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
IHAFMDNN_01726	622312.ROSEINA2194_02720	1.54e-127	366.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
IHAFMDNN_01727	585394.RHOM_08595	2.25e-305	836.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
IHAFMDNN_01728	585394.RHOM_08590	2.31e-258	708.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
IHAFMDNN_01729	585394.RHOM_08585	4.27e-233	652.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
IHAFMDNN_01730	585394.RHOM_08580	0.0	2010.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
IHAFMDNN_01731	622312.ROSEINA2194_01352	2.5e-146	414.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
IHAFMDNN_01732	397291.C804_04092	1.78e-163	476.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,27TN6@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
IHAFMDNN_01733	585394.RHOM_14885	6.18e-37	130.0	COG1669@1|root,COG1669@2|Bacteria,1VBYU@1239|Firmicutes,24N0Y@186801|Clostridia	186801|Clostridia	S	TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 family	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind
IHAFMDNN_01734	1469948.JPNB01000001_gene1957	6.41e-57	181.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
IHAFMDNN_01735	585394.RHOM_11675	7.58e-121	355.0	29TA1@1|root,30EH1@2|Bacteria,1V43N@1239|Firmicutes,24IGU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01737	585394.RHOM_11420	4.09e-177	508.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
IHAFMDNN_01738	622312.ROSEINA2194_02225	7.06e-81	250.0	COG4862@1|root,COG4862@2|Bacteria	2|Bacteria	NOT	establishment of competence for transformation	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
IHAFMDNN_01741	1235790.C805_01468	1.9e-74	238.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
IHAFMDNN_01742	397288.C806_01355	5.43e-256	725.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,27KFU@186928|unclassified Lachnospiraceae	186801|Clostridia	U	V-type ATPase 116kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
IHAFMDNN_01743	397290.C810_03102	7.44e-57	180.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,27MUF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
IHAFMDNN_01744	397288.C806_01357	2.68e-49	158.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,27NKU@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
IHAFMDNN_01745	357809.Cphy_3443	1.99e-21	94.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,21Z0G@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
IHAFMDNN_01746	397288.C806_01359	0.0	930.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,27IS3@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
IHAFMDNN_01747	1235790.C805_01474	5.62e-272	751.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,25VDA@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
IHAFMDNN_01748	1235790.C805_01475	8.71e-104	305.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,25WFD@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
IHAFMDNN_01749	1235800.C819_00237	2.78e-173	497.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,27J37@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
IHAFMDNN_01750	585394.RHOM_08405	4.43e-264	728.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia	186801|Clostridia	C	carboxylase	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
IHAFMDNN_01751	585394.RHOM_01390	1.35e-120	392.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia	186801|Clostridia	J	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
IHAFMDNN_01752	585394.RHOM_01395	3.89e-87	261.0	COG1971@1|root,COG1971@2|Bacteria,1V9RZ@1239|Firmicutes,24KSZ@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
IHAFMDNN_01753	622312.ROSEINA2194_02404	1.77e-289	807.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
IHAFMDNN_01754	622312.ROSEINA2194_02405	5.68e-95	285.0	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
IHAFMDNN_01755	585394.RHOM_01415	2.89e-59	191.0	2C456@1|root,32S3D@2|Bacteria,1VBI4@1239|Firmicutes,24N4Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01757	585394.RHOM_01425	1.75e-238	671.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia	186801|Clostridia	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
IHAFMDNN_01758	585394.RHOM_01430	8.5e-204	567.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia	186801|Clostridia	O	PFAM AIR synthase related protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
IHAFMDNN_01759	622312.ROSEINA2194_02409	7.69e-105	303.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
IHAFMDNN_01760	585394.RHOM_01440	4.23e-266	730.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
IHAFMDNN_01761	585394.RHOM_01445	2.06e-121	346.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
IHAFMDNN_01762	585394.RHOM_01450	3.15e-179	502.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IHAFMDNN_01763	585394.RHOM_01455	1.04e-191	534.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
IHAFMDNN_01764	1123009.AUID01000003_gene1930	1.43e-33	134.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,26AJH@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_01765	1280689.AUJC01000003_gene1384	9.69e-77	241.0	COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,24ATG@186801|Clostridia,36WSQ@31979|Clostridiaceae	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
IHAFMDNN_01766	140626.JHWB01000016_gene2319	2.45e-42	159.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
IHAFMDNN_01767	585394.RHOM_06550	5.99e-78	239.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
IHAFMDNN_01768	585394.RHOM_07990	6.67e-141	400.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_01769	585394.RHOM_07985	6.77e-234	660.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_01770	622312.ROSEINA2194_00211	0.0	969.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
IHAFMDNN_01771	471875.RUMLAC_01414	4.38e-102	295.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,3WJ68@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
IHAFMDNN_01772	585394.RHOM_02270	5.88e-157	451.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IHAFMDNN_01773	1256908.HMPREF0373_02800	5.92e-84	257.0	COG3619@1|root,COG3619@2|Bacteria,1VBGA@1239|Firmicutes,24KG3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
IHAFMDNN_01775	622312.ROSEINA2194_01459	1.08e-274	755.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia	186801|Clostridia	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
IHAFMDNN_01776	585394.RHOM_02240	9.79e-210	598.0	COG0739@1|root,COG1388@1|root,COG3583@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
IHAFMDNN_01777	622312.ROSEINA2194_01457	1.27e-85	256.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
IHAFMDNN_01778	622312.ROSEINA2194_01455	1.88e-130	384.0	2DCHY@1|root,2ZE7V@2|Bacteria,1UMSB@1239|Firmicutes,25FCG@186801|Clostridia	186801|Clostridia	-	-	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
IHAFMDNN_01779	585394.RHOM_13135	0.0	1946.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
IHAFMDNN_01780	622312.ROSEINA2194_01453	1.77e-112	325.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
IHAFMDNN_01781	585394.RHOM_13145	1.68e-144	411.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
IHAFMDNN_01782	397291.C804_04827	1.91e-136	391.0	COG0395@1|root,COG0395@2|Bacteria,1TP14@1239|Firmicutes,2481Z@186801|Clostridia,27KBY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
IHAFMDNN_01783	1226325.HMPREF1548_05296	1.45e-200	565.0	COG3405@1|root,COG3405@2|Bacteria,1U1E1@1239|Firmicutes,24878@186801|Clostridia,36FZI@31979|Clostridiaceae	186801|Clostridia	G	family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
IHAFMDNN_01784	1280390.CBQR020000071_gene1456	0.0	906.0	2DB7A@1|root,2Z7KK@2|Bacteria,1TQ2C@1239|Firmicutes,4HFKE@91061|Bacilli,26S01@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
IHAFMDNN_01785	585394.RHOM_05745	5.07e-251	707.0	COG2755@1|root,COG2755@2|Bacteria,1TPYH@1239|Firmicutes,2486S@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Lipase_GDSL_2
IHAFMDNN_01786	1163671.JAGI01000002_gene2603	2.44e-246	691.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,36ES1@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
IHAFMDNN_01787	585394.RHOM_10990	1.37e-179	507.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
IHAFMDNN_01788	622312.ROSEINA2194_04213	1.03e-250	696.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
IHAFMDNN_01789	622312.ROSEINA2194_04214	0.0	877.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
IHAFMDNN_01790	622312.ROSEINA2194_04215	4.2e-181	506.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
IHAFMDNN_01791	411489.CLOL250_01411	2.84e-62	201.0	2EX79@1|root,33QI5@2|Bacteria,1VS8K@1239|Firmicutes,24YCQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01792	622312.ROSEINA2194_01230	0.0	958.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
IHAFMDNN_01793	411462.DORLON_02488	7.82e-156	442.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,27VGK@189330|Dorea	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
IHAFMDNN_01794	622312.ROSEINA2194_04370	2.79e-158	462.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
IHAFMDNN_01795	585394.RHOM_05375	1.38e-191	533.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
IHAFMDNN_01796	585394.RHOM_05370	1.54e-23	98.2	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
IHAFMDNN_01797	585394.RHOM_03855	1.56e-256	703.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
IHAFMDNN_01798	411463.EUBVEN_02011	3.87e-160	451.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
IHAFMDNN_01799	411463.EUBVEN_02080	2.3e-195	551.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,25UZ8@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
IHAFMDNN_01800	622312.ROSEINA2194_00928	1.61e-17	80.9	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
IHAFMDNN_01801	622312.ROSEINA2194_00929	0.0	886.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
IHAFMDNN_01802	585394.RHOM_06865	6.49e-46	150.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
IHAFMDNN_01803	585394.RHOM_04910	0.0	1223.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
IHAFMDNN_01804	585394.RHOM_04905	4.11e-191	549.0	COG0116@1|root,COG0116@2|Bacteria,1TT5F@1239|Firmicutes,249VY@186801|Clostridia	186801|Clostridia	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,UPF0020
IHAFMDNN_01805	585394.RHOM_04900	2.79e-105	310.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia	186801|Clostridia	M	n-acetylmuramoyl-l-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
IHAFMDNN_01807	585394.RHOM_04880	1.21e-114	346.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
IHAFMDNN_01809	622312.ROSEINA2194_02626	2.46e-85	255.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
IHAFMDNN_01810	585394.RHOM_06010	6.47e-198	556.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
IHAFMDNN_01811	622312.ROSEINA2194_01565	4.22e-97	288.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia	186801|Clostridia	L	Ribonuclease HI	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
IHAFMDNN_01812	585394.RHOM_06000	7.1e-82	253.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
IHAFMDNN_01813	585394.RHOM_05995	3.28e-61	189.0	2F3F9@1|root,33W92@2|Bacteria,1VVFD@1239|Firmicutes,25130@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01814	357809.Cphy_0713	9.01e-137	392.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,21Y17@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
IHAFMDNN_01815	1121296.JONJ01000004_gene974	3.73e-50	162.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,222ZV@1506553|Lachnoclostridium	186801|Clostridia	S	Thioesterase superfamily	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
IHAFMDNN_01816	585394.RHOM_04865	0.0	1116.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
IHAFMDNN_01817	622312.ROSEINA2194_02283	6.31e-07	48.9	2FKRU@1|root,34CCB@2|Bacteria,1W1ZA@1239|Firmicutes,2576Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01818	1121115.AXVN01000018_gene43	3.86e-146	425.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
IHAFMDNN_01819	585394.RHOM_08450	1.22e-179	513.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
IHAFMDNN_01820	585394.RHOM_08445	3.25e-182	518.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
IHAFMDNN_01822	585394.RHOM_13875	5.06e-125	362.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE_1	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_01825	585394.RHOM_04785	9.41e-75	225.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01826	622312.ROSEINA2194_03436	0.0	1234.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
IHAFMDNN_01827	622312.ROSEINA2194_03438	1.39e-22	108.0	COG5184@1|root,COG5184@2|Bacteria,1VDTD@1239|Firmicutes,25FD2@186801|Clostridia	186801|Clostridia	DZ	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
IHAFMDNN_01828	585394.RHOM_04750	1.41e-161	458.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
IHAFMDNN_01829	585394.RHOM_04745	5.34e-257	709.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
IHAFMDNN_01830	585394.RHOM_04740	1.93e-195	545.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
IHAFMDNN_01831	585394.RHOM_04735	4.16e-110	322.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01832	585394.RHOM_04730	1.05e-273	754.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia	186801|Clostridia	I	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
IHAFMDNN_01833	585394.RHOM_05285	9.35e-294	805.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia	186801|Clostridia	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
IHAFMDNN_01834	397290.C810_04420	6.1e-135	388.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,27IKR@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
IHAFMDNN_01835	585394.RHOM_12335	1.76e-82	265.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	wzc	-	2.7.10.1,2.7.10.2	ko:K08252,ko:K08253,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
IHAFMDNN_01836	585394.RHOM_12330	6.43e-121	360.0	2A542@1|root,30TSQ@2|Bacteria,1V4Q2@1239|Firmicutes,24ISW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01839	585394.RHOM_12310	3.66e-225	627.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
IHAFMDNN_01840	585394.RHOM_12305	7.75e-198	556.0	COG0438@1|root,COG0438@2|Bacteria,1UI11@1239|Firmicutes,24CV8@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
IHAFMDNN_01841	585394.RHOM_12300	1.03e-207	582.0	COG0438@1|root,COG0438@2|Bacteria,1VE1G@1239|Firmicutes	1239|Firmicutes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
IHAFMDNN_01842	585394.RHOM_12295	6.17e-170	480.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia	186801|Clostridia	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
IHAFMDNN_01843	585394.RHOM_12290	1.72e-152	436.0	COG1216@1|root,COG1216@2|Bacteria,1UD0A@1239|Firmicutes,24GXB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GNT-I,Glycos_transf_2
IHAFMDNN_01844	585394.RHOM_12285	1.58e-150	428.0	COG1216@1|root,COG1216@2|Bacteria,1VBWR@1239|Firmicutes,24NB1@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_01845	585394.RHOM_12280	7e-134	389.0	COG1216@1|root,COG1216@2|Bacteria,1VAHM@1239|Firmicutes,24MBF@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_01846	552531.BIF_02151	1.35e-110	338.0	COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
IHAFMDNN_01848	742740.HMPREF9474_03791	3.79e-11	69.7	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,21YX0@1506553|Lachnoclostridium	186801|Clostridia	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
IHAFMDNN_01849	585394.RHOM_09175	1.55e-231	643.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
IHAFMDNN_01850	585394.RHOM_01235	0.0	909.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
IHAFMDNN_01851	1280679.ATVX01000005_gene1204	4.57e-34	126.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,4BW72@830|Butyrivibrio	186801|Clostridia	P	PDGLE domain	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
IHAFMDNN_01852	457396.CSBG_01568	1.9e-92	280.0	COG0619@1|root,COG0619@2|Bacteria,1U6XW@1239|Firmicutes,24EV0@186801|Clostridia,36FJU@31979|Clostridiaceae	186801|Clostridia	P	Cobalt ABC transporter, permease	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
IHAFMDNN_01853	1235792.C808_04034	7.49e-105	311.0	COG1122@1|root,COG1122@2|Bacteria,1TSSM@1239|Firmicutes,249KS@186801|Clostridia,27KCE@186928|unclassified Lachnospiraceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
IHAFMDNN_01855	33035.JPJF01000061_gene3670	0.0	1730.0	COG1196@1|root,COG3867@1|root,COG5492@1|root,COG1196@2|Bacteria,COG3867@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia	186801|Clostridia	N	endoglucanase-related protein, glucosyl hydrolase family 9 protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
IHAFMDNN_01856	397291.C804_04887	0.0	1083.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_01857	1469948.JPNB01000002_gene2919	8.23e-154	461.0	COG2972@1|root,COG2972@2|Bacteria,1TPUF@1239|Firmicutes,2491H@186801|Clostridia,36DCG@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
IHAFMDNN_01858	585394.RHOM_10905	0.0	1196.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
IHAFMDNN_01859	357809.Cphy_2058	2.87e-155	455.0	COG2730@1|root,COG2730@2|Bacteria,1UVAD@1239|Firmicutes,25KF9@186801|Clostridia,223EG@1506553|Lachnoclostridium	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
IHAFMDNN_01860	1123075.AUDP01000048_gene1544	4.46e-57	195.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3WHDK@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_01861	585394.RHOM_05925	1.73e-244	684.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
IHAFMDNN_01862	515620.EUBELI_00163	4.01e-279	771.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
IHAFMDNN_01863	658086.HMPREF0994_07307	1.21e-229	645.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia,27UAP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01864	1226325.HMPREF1548_05144	1.59e-85	262.0	2A92C@1|root,30Y6D@2|Bacteria,1V59Y@1239|Firmicutes,25HP5@186801|Clostridia,36I7M@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
IHAFMDNN_01865	1226325.HMPREF1548_05145	0.0	1464.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,36EUY@31979|Clostridiaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
IHAFMDNN_01866	556261.HMPREF0240_03393	3.84e-90	285.0	COG4924@1|root,COG4924@2|Bacteria,1V0BQ@1239|Firmicutes,24DRK@186801|Clostridia,36PW8@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
IHAFMDNN_01867	1235793.C809_04227	6.49e-106	313.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,27N1X@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
IHAFMDNN_01868	585394.RHOM_12890	7.02e-153	440.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
IHAFMDNN_01869	1395513.P343_07995	1.96e-195	552.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,4H9S2@91061|Bacilli,26Q1H@186821|Sporolactobacillaceae	91061|Bacilli	S	Phage terminase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_3,Terminase_6,Terminase_6C
IHAFMDNN_01870	33035.JPJF01000106_gene3130	1.03e-26	102.0	2BXU8@1|root,32YRQ@2|Bacteria,1VG7H@1239|Firmicutes,24SHP@186801|Clostridia,3Y20C@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01871	1042156.CXIVA_01850	4.37e-224	632.0	2CEGT@1|root,2Z7ZB@2|Bacteria,1TP3Y@1239|Firmicutes,24CBJ@186801|Clostridia,36HMF@31979|Clostridiaceae	186801|Clostridia	S	Phage portal protein, SPP1 Gp6-like	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
IHAFMDNN_01872	742740.HMPREF9474_02356	6.26e-135	413.0	COG2369@1|root,COG2369@2|Bacteria,1U6KJ@1239|Firmicutes,24AM0@186801|Clostridia,220AG@1506553|Lachnoclostridium	186801|Clostridia	M	Phage head morphogenesis protein, SPP1 gp7 family	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Phage_Mu_F
IHAFMDNN_01873	1042156.CXIVA_00720	1.22e-58	191.0	2AY8I@1|root,31QAU@2|Bacteria,1U45W@1239|Firmicutes,24T5D@186801|Clostridia,36NSI@31979|Clostridiaceae	186801|Clostridia	S	Phage minor structural protein GP20	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
IHAFMDNN_01874	610130.Closa_1395	5.05e-155	444.0	2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,24FZN@186801|Clostridia,21XYR@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01875	1123511.KB905868_gene180	1.61e-33	119.0	2DMP3@1|root,32ST4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
IHAFMDNN_01876	608534.GCWU000341_02290	1.38e-35	125.0	2E844@1|root,332HW@2|Bacteria,1VI21@1239|Firmicutes,24Q25@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01877	742740.HMPREF9474_02350	8.31e-72	220.0	2BT3Y@1|root,32N8H@2|Bacteria,1U4T1@1239|Firmicutes,25PZF@186801|Clostridia,221ES@1506553|Lachnoclostridium	186801|Clostridia	S	Bacteriophage HK97-gp10, putative tail-component	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
IHAFMDNN_01878	742740.HMPREF9474_02349	1.4e-38	134.0	2E3R8@1|root,32YNZ@2|Bacteria,1VIVW@1239|Firmicutes,24SI8@186801|Clostridia,221GM@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01880	742740.HMPREF9474_02347	3.98e-233	650.0	28IGV@1|root,2Z8I6@2|Bacteria,1TP1Y@1239|Firmicutes,24AS0@186801|Clostridia,220YZ@1506553|Lachnoclostridium	186801|Clostridia	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C,Phage_sheath_1N
IHAFMDNN_01881	1235790.C805_00599	2.77e-89	264.0	2CBAP@1|root,2ZCKJ@2|Bacteria,1V2H5@1239|Firmicutes,24FQW@186801|Clostridia,25YN6@186806|Eubacteriaceae	186801|Clostridia	S	Phage tail tube protein	xkdM	-	-	-	-	-	-	-	-	-	-	-	DUF2001
IHAFMDNN_01882	742740.HMPREF9474_02345	3.7e-73	222.0	2CIH9@1|root,31MHP@2|Bacteria,1V74S@1239|Firmicutes,24JK6@186801|Clostridia,221AV@1506553|Lachnoclostridium	186801|Clostridia	S	Phage XkdN-like tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
IHAFMDNN_01884	622312.ROSEINA2194_00527	1.18e-114	351.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia	186801|Clostridia	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
IHAFMDNN_01885	585394.RHOM_13200	0.0	1153.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
IHAFMDNN_01886	585394.RHOM_13195	2.9e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1UFZA@1239|Firmicutes,24MM8@186801|Clostridia	186801|Clostridia	G	Phosphocarrier protein (Hpr)	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IHAFMDNN_01887	622312.ROSEINA2194_02903	2.05e-32	121.0	2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01888	585394.RHOM_13185	6.04e-271	743.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
IHAFMDNN_01889	585394.RHOM_13180	3.91e-174	492.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
IHAFMDNN_01890	622312.ROSEINA2194_03797	5.86e-142	414.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
IHAFMDNN_01891	622312.ROSEINA2194_03795	3.83e-285	784.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IHAFMDNN_01892	585394.RHOM_13160	6.35e-262	722.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
IHAFMDNN_01893	585394.RHOM_13155	2.53e-246	679.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia	186801|Clostridia	G	glucose-1-phosphate adenylyltransferase GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
IHAFMDNN_01894	622312.ROSEINA2194_01451	1.19e-50	160.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
IHAFMDNN_01895	585394.RHOM_07390	4.17e-261	726.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
IHAFMDNN_01897	1120746.CCNL01000008_gene555	3.26e-98	308.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,2.1.1.131,2.1.1.132,2.1.1.196,2.1.1.289,3.7.1.12,4.99.1.4	ko:K00595,ko:K02191,ko:K02304,ko:K03399,ko:K05895,ko:K05934,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05149,R05150,R05180,R05809,R05812,R05813,R07772,R07774,R07775	RC00003,RC01012,RC01034,RC01279,RC01280,RC01293,RC01545,RC02052,RC02053,RC02054,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15725	CbiJ,Methyltransf_31,TP_methylase
IHAFMDNN_01898	585394.RHOM_04285	1.87e-246	676.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
IHAFMDNN_01899	526218.Sterm_4199	6.18e-51	175.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
IHAFMDNN_01901	585394.RHOM_06630	1.27e-145	418.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_01902	622312.ROSEINA2194_01766	2.18e-314	862.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
IHAFMDNN_01903	585394.RHOM_06640	7.59e-136	395.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
IHAFMDNN_01904	585394.RHOM_06645	1.17e-267	744.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
IHAFMDNN_01905	585394.RHOM_06665	1.79e-101	300.0	COG2364@1|root,COG2364@2|Bacteria,1V7N6@1239|Firmicutes,25CWQ@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01906	585394.RHOM_06660	5.38e-60	194.0	2DY6R@1|root,32V4T@2|Bacteria,1VDMI@1239|Firmicutes,24D1Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01907	585394.RHOM_06670	5.9e-172	483.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
IHAFMDNN_01908	585394.RHOM_06675	2.39e-293	803.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
IHAFMDNN_01909	622312.ROSEINA2194_03293	5.85e-141	402.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
IHAFMDNN_01911	585394.RHOM_16075	1.87e-102	297.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia	186801|Clostridia	F	cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
IHAFMDNN_01912	585394.RHOM_16080	1.24e-144	408.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
IHAFMDNN_01913	622312.ROSEINA2194_04355	7.86e-80	240.0	COG0394@1|root,COG0394@2|Bacteria,1UIG5@1239|Firmicutes,25EMJ@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
IHAFMDNN_01914	622312.ROSEINA2194_04354	7.46e-60	194.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
IHAFMDNN_01915	585394.RHOM_07440	5.47e-123	352.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
IHAFMDNN_01916	585394.RHOM_07445	8.4e-268	738.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
IHAFMDNN_01917	1256908.HMPREF0373_02029	3.13e-184	522.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,25VKN@186806|Eubacteriaceae	186801|Clostridia	HP	K02013 iron complex transport system ATP-binding protein	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
IHAFMDNN_01918	1256908.HMPREF0373_02030	1.94e-178	504.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,25VB9@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
IHAFMDNN_01919	1256908.HMPREF0373_02031	6.55e-257	718.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,25UTP@186806|Eubacteriaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
IHAFMDNN_01920	622312.ROSEINA2194_01846	4.52e-280	779.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia	186801|Clostridia	H	cobalt chelatase	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
IHAFMDNN_01922	585394.RHOM_14165	1.54e-156	468.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2,sCache_3_3
IHAFMDNN_01923	515620.EUBELI_20098	4.49e-187	531.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,25WUW@186806|Eubacteriaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IHAFMDNN_01925	1458462.JNLK01000001_gene4	1.83e-80	245.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,27MEA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
IHAFMDNN_01926	585394.RHOM_12475	0.0	1217.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
IHAFMDNN_01928	585394.RHOM_05985	1.41e-112	335.0	COG5513@1|root,COG5513@2|Bacteria,1UIU3@1239|Firmicutes,25ERV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3298)	rsiV	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
IHAFMDNN_01929	585394.RHOM_05980	1.66e-62	197.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
IHAFMDNN_01930	1415775.U729_2133	1.01e-72	222.0	COG3153@1|root,COG3153@2|Bacteria,1UK0D@1239|Firmicutes,25FG9@186801|Clostridia,36V06@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
IHAFMDNN_01931	622312.ROSEINA2194_02245	1.08e-143	421.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24HT2@186801|Clostridia	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
IHAFMDNN_01932	585394.RHOM_04015	4.98e-249	689.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
IHAFMDNN_01933	585394.RHOM_04020	1.92e-266	736.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
IHAFMDNN_01934	622312.ROSEINA2194_02248	6.21e-164	461.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
IHAFMDNN_01935	585394.RHOM_04030	9.98e-195	542.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
IHAFMDNN_01936	1410650.JHWL01000026_gene20	4.79e-49	189.0	28I6K@1|root,2Z89I@2|Bacteria,1UQ1M@1239|Firmicutes,24A0B@186801|Clostridia,4BYHE@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01938	585394.RHOM_06725	1.41e-194	574.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
IHAFMDNN_01939	622312.ROSEINA2194_02031	4.8e-158	444.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
IHAFMDNN_01940	585394.RHOM_14750	7.73e-93	280.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
IHAFMDNN_01941	1235799.C818_03344	1.12e-103	311.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,27IRB@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
IHAFMDNN_01942	411468.CLOSCI_03983	2.85e-92	276.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,21ZN5@1506553|Lachnoclostridium	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
IHAFMDNN_01943	720554.Clocl_3524	1e-70	223.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
IHAFMDNN_01944	585394.RHOM_14715	2.1e-82	248.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia	186801|Clostridia	M	Acetyltransferase GNAT family	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
IHAFMDNN_01945	585394.RHOM_14710	7.89e-186	521.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia	186801|Clostridia	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
IHAFMDNN_01946	1256908.HMPREF0373_01077	9.73e-194	538.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,25VPS@186806|Eubacteriaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
IHAFMDNN_01947	585394.RHOM_14635	4.26e-262	728.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia	186801|Clostridia	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
IHAFMDNN_01948	585394.RHOM_14630	9.63e-280	770.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia	186801|Clostridia	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
IHAFMDNN_01949	585394.RHOM_08855	2.52e-76	228.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
IHAFMDNN_01950	622312.ROSEINA2194_02748	2.31e-44	147.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
IHAFMDNN_01951	622312.ROSEINA2194_02747	5.74e-202	569.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
IHAFMDNN_01952	1235790.C805_02008	5.92e-24	92.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,25XPE@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar protein (FlbD)	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
IHAFMDNN_01953	585394.RHOM_06985	1.08e-224	639.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
IHAFMDNN_01954	585394.RHOM_06980	3.05e-55	176.0	2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,24R2S@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	flg	-	-	-	-	-	-	-	-	-	-	-	Flagellar_put
IHAFMDNN_01955	585394.RHOM_06975	1.01e-79	247.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia	186801|Clostridia	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
IHAFMDNN_01956	585394.RHOM_06970	1.18e-88	287.0	COG3144@1|root,COG3144@2|Bacteria,1V4YB@1239|Firmicutes,24JMD@186801|Clostridia	186801|Clostridia	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
IHAFMDNN_01957	585394.RHOM_06965	1.14e-106	318.0	28H98@1|root,2Z7M1@2|Bacteria,1TRE9@1239|Firmicutes,24F21@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
IHAFMDNN_01958	585394.RHOM_06960	1.36e-59	188.0	COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia	186801|Clostridia	NOU	flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
IHAFMDNN_01959	622312.ROSEINA2194_00945	4.32e-270	744.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
IHAFMDNN_01960	585394.RHOM_06950	8.69e-53	179.0	COG1317@1|root,COG1317@2|Bacteria,1V7UQ@1239|Firmicutes	1239|Firmicutes	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
IHAFMDNN_01961	585394.RHOM_06945	1.56e-213	593.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flig	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
IHAFMDNN_01962	622312.ROSEINA2194_00942	1.02e-226	642.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia	186801|Clostridia	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
IHAFMDNN_01963	622312.ROSEINA2194_00941	9.85e-41	137.0	COG1677@1|root,COG1677@2|Bacteria	2|Bacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
IHAFMDNN_01964	585394.RHOM_06925	1.29e-79	238.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia	186801|Clostridia	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
IHAFMDNN_01965	622312.ROSEINA2194_00939	3.78e-58	183.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,24RBE@186801|Clostridia	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
IHAFMDNN_01966	622312.ROSEINA2194_00777	1.13e-127	375.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
IHAFMDNN_01967	585394.RHOM_15700	2.97e-221	612.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
IHAFMDNN_01968	622312.ROSEINA2194_00780	1.09e-175	496.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
IHAFMDNN_01969	585394.RHOM_15690	2.39e-60	187.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01970	585394.RHOM_15685	3.89e-170	477.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
IHAFMDNN_01971	622312.ROSEINA2194_00783	4.22e-204	568.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
IHAFMDNN_01972	622312.ROSEINA2194_00784	4.33e-54	177.0	2ECHQ@1|root,336FZ@2|Bacteria,1VI4C@1239|Firmicutes,24TFT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01973	585394.RHOM_15670	1.7e-93	275.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
IHAFMDNN_01974	411474.COPEUT_01876	0.0	1047.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
IHAFMDNN_01975	445972.ANACOL_00992	1.34e-299	816.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WHDU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
IHAFMDNN_01976	445972.ANACOL_00991	2.17e-43	140.0	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24US2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01977	742740.HMPREF9474_02951	1.71e-265	726.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,21ZPX@1506553|Lachnoclostridium	186801|Clostridia	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
IHAFMDNN_01987	585394.RHOM_05225	7.06e-182	514.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
IHAFMDNN_01988	585394.RHOM_05230	4.91e-138	414.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01989	585394.RHOM_05235	1.83e-15	73.6	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01995	397288.C806_01801	2.35e-13	81.6	COG5492@1|root,COG5492@2|Bacteria,1UDEG@1239|Firmicutes,25I43@186801|Clostridia,27RQX@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
IHAFMDNN_01996	585394.RHOM_05105	7.28e-101	294.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia	186801|Clostridia	F	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
IHAFMDNN_01997	585394.RHOM_05100	1.49e-31	115.0	2E9G7@1|root,333PE@2|Bacteria,1VHIP@1239|Firmicutes,24UC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_01998	585394.RHOM_05095	7.84e-101	292.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
IHAFMDNN_01999	585394.RHOM_09195	1.71e-198	553.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
IHAFMDNN_02000	622312.ROSEINA2194_03149	5.11e-12	63.5	COG4636@1|root,COG4636@2|Bacteria,1V4N9@1239|Firmicutes,24CZ1@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
IHAFMDNN_02001	622312.ROSEINA2194_03149	8.12e-75	227.0	COG4636@1|root,COG4636@2|Bacteria,1V4N9@1239|Firmicutes,24CZ1@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
IHAFMDNN_02003	585394.RHOM_11330	1.56e-98	287.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
IHAFMDNN_02004	622312.ROSEINA2194_00724	0.0	1219.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
IHAFMDNN_02005	622312.ROSEINA2194_00725	2.58e-32	114.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes	1239|Firmicutes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
IHAFMDNN_02006	585394.RHOM_11345	2.21e-248	690.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
IHAFMDNN_02007	457415.HMPREF1006_00874	1.65e-113	359.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,3TB48@508458|Synergistetes	508458|Synergistetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg
IHAFMDNN_02009	585394.RHOM_11360	1.13e-122	360.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
IHAFMDNN_02010	622312.ROSEINA2194_02856	3.18e-228	639.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
IHAFMDNN_02011	585394.RHOM_11370	6.13e-175	503.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
IHAFMDNN_02012	585394.RHOM_11375	2.15e-164	464.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
IHAFMDNN_02013	936574.HMPREF1508_1331	7.94e-41	135.0	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia	186801|Clostridia	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
IHAFMDNN_02014	1410628.JNKS01000004_gene2041	8.11e-73	219.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia,27NM5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
IHAFMDNN_02015	622312.ROSEINA2194_02915	5.23e-246	683.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_02016	622312.ROSEINA2194_00445	9.87e-54	171.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
IHAFMDNN_02017	622312.ROSEINA2194_00446	0.0	1225.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
IHAFMDNN_02018	180332.JTGN01000005_gene2749	3.05e-19	79.0	2EIM1@1|root,33CCB@2|Bacteria,1VM79@1239|Firmicutes,24UNI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02019	622312.ROSEINA2194_04435	4.57e-130	371.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
IHAFMDNN_02020	585394.RHOM_14320	2.13e-193	537.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
IHAFMDNN_02021	622312.ROSEINA2194_04433	3.69e-207	575.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
IHAFMDNN_02022	622312.ROSEINA2194_04432	1.76e-106	333.0	COG1652@1|root,COG1652@2|Bacteria,1UIP6@1239|Firmicutes,25EPX@186801|Clostridia	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
IHAFMDNN_02023	585394.RHOM_14305	1.41e-184	525.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02024	622312.ROSEINA2194_04430	1.61e-63	205.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24N5I@186801|Clostridia	186801|Clostridia	S	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
IHAFMDNN_02025	622312.ROSEINA2194_00849	2.13e-140	400.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,24G6Q@186801|Clostridia	186801|Clostridia	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
IHAFMDNN_02026	585394.RHOM_01380	3.79e-106	309.0	COG1309@1|root,COG1309@2|Bacteria,1V44I@1239|Firmicutes,24I73@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
IHAFMDNN_02027	622312.ROSEINA2194_02400	1.48e-163	468.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
IHAFMDNN_02028	622312.ROSEINA2194_02399	4.22e-41	135.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S7B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02029	622312.ROSEINA2194_02398	4.18e-230	651.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
IHAFMDNN_02030	585394.RHOM_01330	1.49e-89	267.0	COG3247@1|root,COG3247@2|Bacteria,1VBAR@1239|Firmicutes,25CUJ@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
IHAFMDNN_02031	585394.RHOM_01325	4.6e-97	284.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
IHAFMDNN_02032	585394.RHOM_01265	5.07e-165	467.0	2E1XD@1|root,32X6E@2|Bacteria,1VC0W@1239|Firmicutes,24P6H@186801|Clostridia	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
IHAFMDNN_02033	585394.RHOM_12780	0.0	1127.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
IHAFMDNN_02034	585394.RHOM_12785	4.85e-187	544.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
IHAFMDNN_02035	585394.RHOM_10215	0.0	972.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
IHAFMDNN_02036	585394.RHOM_03700	3.56e-142	406.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
IHAFMDNN_02037	622312.ROSEINA2194_01879	4.52e-72	219.0	2E3N2@1|root,32YK7@2|Bacteria,1VEYM@1239|Firmicutes,24QJ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02038	1280698.AUJS01000100_gene153	3.19e-129	369.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,248T4@186801|Clostridia,27W6C@189330|Dorea	186801|Clostridia	O	Pyroglutamyl peptidase	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
IHAFMDNN_02039	585394.RHOM_03705	1e-90	295.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
IHAFMDNN_02040	585394.RHOM_03710	3.86e-135	405.0	COG0845@1|root,COG0845@2|Bacteria,1V96V@1239|Firmicutes,24BEV@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
IHAFMDNN_02041	585394.RHOM_03715	6.1e-223	629.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,24AWU@186801|Clostridia	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
IHAFMDNN_02043	585394.RHOM_03725	5.89e-128	369.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
IHAFMDNN_02044	585394.RHOM_03730	4.82e-116	338.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
IHAFMDNN_02045	411902.CLOBOL_06104	1.72e-112	331.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,24KJZ@186801|Clostridia,22041@1506553|Lachnoclostridium	186801|Clostridia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
IHAFMDNN_02046	1458462.JNLK01000001_gene1936	2.28e-159	486.0	COG2206@1|root,COG3275@1|root,COG3292@1|root,COG2206@2|Bacteria,COG3275@2|Bacteria,COG3292@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
IHAFMDNN_02047	1507.HMPREF0262_00674	1.63e-14	77.0	2CCXQ@1|root,32RWN@2|Bacteria,1W2JS@1239|Firmicutes	1239|Firmicutes	S	Host cell surface-exposed lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_Ltp
IHAFMDNN_02048	585394.RHOM_11755	0.0	890.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia	186801|Clostridia	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
IHAFMDNN_02049	1235793.C809_03429	5.82e-85	266.0	2DBCR@1|root,2Z8FA@2|Bacteria,1V8ZT@1239|Firmicutes,24KB5@186801|Clostridia,27MF2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02050	585394.RHOM_14940	0.0	1147.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
IHAFMDNN_02051	585394.RHOM_15950	4.1e-268	744.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
IHAFMDNN_02052	585394.RHOM_15955	8.31e-166	466.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
IHAFMDNN_02053	585394.RHOM_15960	3.6e-162	457.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,24A7G@186801|Clostridia	186801|Clostridia	P	phosphonate ABC transporter, permease protein PhnE	phnE_1	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
IHAFMDNN_02054	585394.RHOM_15965	2.4e-157	444.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,249GS@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
IHAFMDNN_02055	585394.RHOM_15970	1.07e-200	563.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,24A3Q@186801|Clostridia	186801|Clostridia	P	ABC-type phosphate phosphonate transport system periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
IHAFMDNN_02056	585394.RHOM_15975	4.56e-165	469.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia	186801|Clostridia	K	Transcriptional	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_02057	1226325.HMPREF1548_01833	3.6e-94	283.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,36F35@31979|Clostridiaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
IHAFMDNN_02058	1430331.EP10_03905	1.08e-75	242.0	COG0827@1|root,COG0827@2|Bacteria,1UZYA@1239|Firmicutes	1239|Firmicutes	L	BsuBI/PstI restriction endonuclease C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	BsuBI_PstI_RE
IHAFMDNN_02059	397290.C810_03430	6.19e-81	263.0	COG0827@1|root,COG0827@2|Bacteria,1UXY1@1239|Firmicutes,24B3U@186801|Clostridia,27R34@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Eco57I restriction-modification methylase	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase
IHAFMDNN_02061	585394.RHOM_00905	1.58e-65	200.0	COG2315@1|root,COG2315@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain protein	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
IHAFMDNN_02062	478749.BRYFOR_05176	3.04e-222	625.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_02063	622312.ROSEINA2194_00484	2.82e-206	605.0	COG0369@1|root,COG0534@1|root,COG0534@2|Bacteria,COG1151@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_02064	585394.RHOM_02135	2.84e-137	396.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
IHAFMDNN_02065	483218.BACPEC_02964	7.13e-37	127.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,269QT@186813|unclassified Clostridiales	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
IHAFMDNN_02066	585394.RHOM_02150	3.86e-81	242.0	COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,24K11@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
IHAFMDNN_02067	585394.RHOM_01250	1.39e-160	466.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
IHAFMDNN_02068	478749.BRYFOR_08058	7.96e-94	296.0	COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,24N6F@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_8
IHAFMDNN_02069	478749.BRYFOR_08059	1.16e-188	537.0	COG0477@1|root,COG2814@2|Bacteria,1TZWA@1239|Firmicutes,24C48@186801|Clostridia	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
IHAFMDNN_02070	622312.ROSEINA2194_01504	6.41e-217	607.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24825@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775,ko:K02529	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
IHAFMDNN_02071	483218.BACPEC_02513	1.71e-79	239.0	COG1846@1|root,COG1846@2|Bacteria,1V8Z3@1239|Firmicutes,24I7U@186801|Clostridia,26BAN@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
IHAFMDNN_02072	1392493.JIAB01000001_gene729	1.37e-307	841.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,27J2Z@186928|unclassified Lachnospiraceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
IHAFMDNN_02073	397291.C804_04903	1e-215	673.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,27JHC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
IHAFMDNN_02074	1235802.C823_05147	2.45e-180	513.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
IHAFMDNN_02075	445972.ANACOL_01323	4.31e-43	155.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WHT6@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
IHAFMDNN_02076	1408306.JHXX01000001_gene2019	1.49e-153	447.0	COG2312@1|root,COG2312@2|Bacteria,1V2ED@1239|Firmicutes,24BHP@186801|Clostridia,4BXEN@830|Butyrivibrio	186801|Clostridia	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
IHAFMDNN_02077	622312.ROSEINA2194_03033	5.04e-296	810.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
IHAFMDNN_02078	585394.RHOM_09335	4.86e-55	172.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
IHAFMDNN_02079	622312.ROSEINA2194_01367	0.0	956.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
IHAFMDNN_02080	585394.RHOM_06790	2.99e-233	645.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
IHAFMDNN_02081	585394.RHOM_06795	0.0	1228.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02082	585394.RHOM_06800	6.37e-177	506.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02083	622312.ROSEINA2194_00916	8.58e-72	228.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24IHF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02084	585394.RHOM_06810	3.86e-158	457.0	28KI7@1|root,2ZA3H@2|Bacteria,1V07J@1239|Firmicutes,24EVH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02085	585394.RHOM_06825	3.06e-137	389.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
IHAFMDNN_02086	622312.ROSEINA2194_00922	3.08e-33	117.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
IHAFMDNN_02087	585394.RHOM_08575	1.09e-190	564.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
IHAFMDNN_02088	622312.ROSEINA2194_00846	3.54e-96	298.0	2DNG5@1|root,32XBR@2|Bacteria,1V8W9@1239|Firmicutes,24M9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LprI
IHAFMDNN_02089	658086.HMPREF0994_03302	1.19e-52	169.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
IHAFMDNN_02090	397291.C804_02931	1.92e-108	325.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,27UBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI,ROK
IHAFMDNN_02091	397288.C806_01642	6.73e-118	353.0	COG1609@1|root,COG1609@2|Bacteria,1TT82@1239|Firmicutes,24G8D@186801|Clostridia,27QNK@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_1
IHAFMDNN_02092	702450.CUW_2163	4.21e-190	541.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,3VPJX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Pfam:DUF1237	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
IHAFMDNN_02093	702450.CUW_2164	0.0	1155.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,3VPJS@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
IHAFMDNN_02094	585394.RHOM_00455	2.37e-21	92.4	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
IHAFMDNN_02096	622312.ROSEINA2194_00374	1.12e-159	460.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
IHAFMDNN_02097	1449050.JNLE01000005_gene4149	2.92e-164	491.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae	186801|Clostridia	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
IHAFMDNN_02098	1449050.JNLE01000005_gene4148	5.86e-15	75.1	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IHAFMDNN_02099	592026.GCWU0000282_003030	3.64e-106	317.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
IHAFMDNN_02100	592026.GCWU0000282_003029	1.78e-145	441.0	COG1173@1|root,COG5184@1|root,COG1173@2|Bacteria,COG5184@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
IHAFMDNN_02101	1449050.JNLE01000005_gene4146	4.19e-205	571.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
IHAFMDNN_02102	592026.GCWU0000282_003027	5.62e-206	587.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
IHAFMDNN_02105	622312.ROSEINA2194_00691	4.25e-217	607.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
IHAFMDNN_02106	585394.RHOM_03045	4.99e-179	502.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
IHAFMDNN_02107	1469948.JPNB01000002_gene2779	1.89e-113	330.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36HYG@31979|Clostridiaceae	186801|Clostridia	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
IHAFMDNN_02108	585394.RHOM_11750	1.12e-161	458.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
IHAFMDNN_02109	585394.RHOM_11745	3.9e-41	140.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
IHAFMDNN_02110	476272.RUMHYD_00772	3e-267	739.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
IHAFMDNN_02111	1256908.HMPREF0373_02435	7.28e-20	80.9	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,25XQV@186806|Eubacteriaceae	186801|Clostridia	S	Six-cysteine peptide SCIFF	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
IHAFMDNN_02112	585394.RHOM_11735	1.77e-314	858.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
IHAFMDNN_02113	585394.RHOM_11730	0.0	1073.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
IHAFMDNN_02114	1235790.C805_00793	3.64e-36	124.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25XSB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
IHAFMDNN_02115	622312.ROSEINA2194_03381	5.37e-289	790.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
IHAFMDNN_02118	585394.RHOM_08030	7.4e-293	800.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
IHAFMDNN_02119	622312.ROSEINA2194_03857	4.6e-108	311.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
IHAFMDNN_02120	575593.HMPREF0491_01365	7.39e-129	370.0	COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,24DQR@186801|Clostridia,27JVP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
IHAFMDNN_02121	397291.C804_02849	1.31e-87	267.0	COG2310@1|root,COG2310@2|Bacteria,1V26C@1239|Firmicutes,24GMA@186801|Clostridia,27N1D@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	-	-	-	-	-	-	-	-	-	-	-	-	TerD
IHAFMDNN_02124	397291.C804_02030	6.06e-283	811.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,27JAC@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
IHAFMDNN_02125	585394.RHOM_10595	1.93e-133	384.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02126	585394.RHOM_10580	6.36e-282	775.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
IHAFMDNN_02127	585394.RHOM_10200	8.26e-268	740.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia	186801|Clostridia	O	feS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
IHAFMDNN_02128	585394.RHOM_10195	2.82e-94	293.0	COG0719@1|root,COG0719@2|Bacteria,1TRQJ@1239|Firmicutes,24ANC@186801|Clostridia	186801|Clostridia	O	SufB sufD domain protein	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
IHAFMDNN_02129	585394.RHOM_10190	3.34e-197	557.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia	186801|Clostridia	E	Cysteine desulfurase	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
IHAFMDNN_02130	585394.RHOM_10060	6.9e-315	861.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
IHAFMDNN_02131	622312.ROSEINA2194_00798	5.94e-314	859.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
IHAFMDNN_02132	585394.RHOM_10070	6.76e-130	379.0	COG0721@1|root,COG1670@1|root,COG0721@2|Bacteria,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia	186801|Clostridia	J	acetyltransferase, GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
IHAFMDNN_02133	622312.ROSEINA2194_00796	6.28e-248	686.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
IHAFMDNN_02134	1469948.JPNB01000002_gene3758	6.4e-284	867.0	COG0366@1|root,COG0366@2|Bacteria,1UIVZ@1239|Firmicutes,25GG5@186801|Clostridia,36VA5@31979|Clostridiaceae	186801|Clostridia	GN	Bacterial pullanase-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,PUD
IHAFMDNN_02135	556261.HMPREF0240_01005	4.56e-121	364.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,36DFY@31979|Clostridiaceae	186801|Clostridia	L	domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
IHAFMDNN_02136	622312.ROSEINA2194_02986	6.42e-106	308.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
IHAFMDNN_02137	1235799.C818_01516	1.97e-170	528.0	COG3210@1|root,COG3210@2|Bacteria,1UJX3@1239|Firmicutes,25FCY@186801|Clostridia,27IUC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
IHAFMDNN_02138	1280671.AUJH01000002_gene1825	1.66e-39	155.0	COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,249J7@186801|Clostridia,4C1VP@830|Butyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
IHAFMDNN_02139	622312.ROSEINA2194_02987	3.33e-144	409.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia	186801|Clostridia	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
IHAFMDNN_02140	585394.RHOM_11205	3.68e-313	856.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
IHAFMDNN_02141	585394.RHOM_11200	3.62e-85	252.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
IHAFMDNN_02142	585394.RHOM_11195	2.3e-161	454.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
IHAFMDNN_02143	622312.ROSEINA2194_02991	2.42e-90	271.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
IHAFMDNN_02144	515620.EUBELI_01734	9.09e-134	391.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
IHAFMDNN_02145	397291.C804_05617	7.4e-94	276.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,27M9G@186928|unclassified Lachnospiraceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
IHAFMDNN_02147	585394.RHOM_07705	2.87e-74	231.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
IHAFMDNN_02149	585394.RHOM_07710	5.91e-282	774.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia	186801|Clostridia	P	aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
IHAFMDNN_02150	622312.ROSEINA2194_03770	5.59e-179	504.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
IHAFMDNN_02151	622312.ROSEINA2194_03771	0.0	909.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
IHAFMDNN_02152	1235802.C823_03200	1.45e-100	298.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,25V4I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
IHAFMDNN_02153	585394.RHOM_07725	0.0	1498.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
IHAFMDNN_02154	585394.RHOM_07730	3.8e-250	702.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia	186801|Clostridia	H	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
IHAFMDNN_02155	585394.RHOM_08620	3.69e-142	411.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
IHAFMDNN_02156	585394.RHOM_08625	2.55e-123	354.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
IHAFMDNN_02158	585394.RHOM_06545	1.45e-115	333.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
IHAFMDNN_02159	585394.RHOM_06540	1.3e-195	555.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
IHAFMDNN_02160	622312.ROSEINA2194_02775	2.27e-132	396.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
IHAFMDNN_02161	411459.RUMOBE_02462	8.33e-147	418.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
IHAFMDNN_02162	411462.DORLON_01513	2.13e-155	439.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,27VIT@189330|Dorea	186801|Clostridia	H	COG COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and THIamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
IHAFMDNN_02163	585394.RHOM_11185	1.56e-308	842.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
IHAFMDNN_02164	1449050.JNLE01000003_gene3109	3.5e-281	783.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,36FE5@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
IHAFMDNN_02165	1121115.AXVN01000104_gene847	9.04e-198	552.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
IHAFMDNN_02166	515620.EUBELI_01895	6.23e-49	157.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
IHAFMDNN_02167	1121115.AXVN01000104_gene849	5.29e-279	778.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
IHAFMDNN_02168	515620.EUBELI_01883	1.49e-168	481.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25W0F@186806|Eubacteriaceae	186801|Clostridia	E	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
IHAFMDNN_02169	515620.EUBELI_01884	9.61e-150	426.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,25VWA@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
IHAFMDNN_02170	515620.EUBELI_01885	3.37e-156	443.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,25ZFW@186806|Eubacteriaceae	186801|Clostridia	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
IHAFMDNN_02171	1280688.AUJB01000008_gene509	1.13e-163	468.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3NI27@46205|Pseudobutyrivibrio	186801|Clostridia	P	PBP superfamily domain	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
IHAFMDNN_02172	585394.RHOM_12465	7e-221	611.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
IHAFMDNN_02173	585394.RHOM_12460	8.36e-152	431.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
IHAFMDNN_02174	585394.RHOM_12455	1.11e-139	400.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
IHAFMDNN_02175	622312.ROSEINA2194_03005	1.33e-36	127.0	COG3951@1|root,COG3951@2|Bacteria,1VICK@1239|Firmicutes,24QXM@186801|Clostridia	186801|Clostridia	MNO	Flagellar rod assembly protein muramidase FlgJ	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
IHAFMDNN_02176	585394.RHOM_12445	0.0	1268.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
IHAFMDNN_02177	622312.ROSEINA2194_02621	2.43e-173	485.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
IHAFMDNN_02178	585394.RHOM_12435	6.4e-192	536.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
IHAFMDNN_02179	622312.ROSEINA2194_02619	8.6e-176	499.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
IHAFMDNN_02180	622312.ROSEINA2194_02618	1.79e-86	264.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
IHAFMDNN_02181	585394.RHOM_12420	1.83e-63	196.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02182	642492.Clole_2676	0.0	1197.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF5110,Glyco_hydro_31
IHAFMDNN_02183	642492.Clole_2677	6.09e-313	881.0	COG4447@1|root,COG4447@2|Bacteria,1VJ96@1239|Firmicutes	1239|Firmicutes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02184	411462.DORLON_00274	6.04e-187	531.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,27VSU@189330|Dorea	186801|Clostridia	H	ATPase of the PP-loop superfamily implicated in cell cycle control	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
IHAFMDNN_02185	622312.ROSEINA2194_04128	2.51e-313	859.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
IHAFMDNN_02186	585394.RHOM_11105	5.42e-192	534.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
IHAFMDNN_02187	585394.RHOM_11110	3.46e-271	744.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia	186801|Clostridia	E	PFAM Cys Met metabolism	mccB	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
IHAFMDNN_02188	471875.RUMLAC_00642	4.3e-147	422.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
IHAFMDNN_02189	585394.RHOM_07320	2.37e-240	665.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
IHAFMDNN_02190	585394.RHOM_07325	1.12e-167	473.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
IHAFMDNN_02191	585394.RHOM_07330	6.72e-96	282.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia	186801|Clostridia	K	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
IHAFMDNN_02192	622312.ROSEINA2194_03686	5.82e-166	469.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
IHAFMDNN_02193	622312.ROSEINA2194_03687	1.19e-46	150.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
IHAFMDNN_02194	622312.ROSEINA2194_03688	1.26e-118	342.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
IHAFMDNN_02195	622312.ROSEINA2194_03689	1.83e-44	146.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes	1239|Firmicutes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
IHAFMDNN_02196	622312.ROSEINA2194_03690	2.37e-289	793.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
IHAFMDNN_02197	585394.RHOM_07360	1.91e-102	299.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
IHAFMDNN_02198	585394.RHOM_07365	6.8e-74	226.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
IHAFMDNN_02199	585394.RHOM_07370	1.25e-95	282.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
IHAFMDNN_02200	585394.RHOM_07375	8.89e-101	293.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
IHAFMDNN_02201	585394.RHOM_07380	7.65e-62	198.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02202	622312.ROSEINA2194_03695	1.91e-20	90.9	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
IHAFMDNN_02203	622312.ROSEINA2194_01730	2.24e-204	566.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
IHAFMDNN_02204	622312.ROSEINA2194_01731	1.75e-259	715.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
IHAFMDNN_02205	1408312.JNJS01000001_gene1438	6.75e-139	397.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3NH3M@46205|Pseudobutyrivibrio	186801|Clostridia	E	Type I 3-dehydroquinase	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
IHAFMDNN_02206	622312.ROSEINA2194_01735	9.41e-98	289.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
IHAFMDNN_02207	622312.ROSEINA2194_01736	8.02e-256	707.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
IHAFMDNN_02208	622312.ROSEINA2194_01737	4.25e-185	521.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia	186801|Clostridia	G	COG COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
IHAFMDNN_02209	622312.ROSEINA2194_01738	8.77e-174	486.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
IHAFMDNN_02210	622312.ROSEINA2194_02447	5.9e-18	83.2	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7
IHAFMDNN_02211	622312.ROSEINA2194_02126	2.07e-43	146.0	2FC79@1|root,344B3@2|Bacteria,1W1AZ@1239|Firmicutes,24W3X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02212	1280694.AUJQ01000011_gene1768	4.55e-133	393.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3NGIB@46205|Pseudobutyrivibrio	186801|Clostridia	J	tRNA synthetases class II (A)	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
IHAFMDNN_02213	1469948.JPNB01000002_gene3250	1.97e-198	560.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,36FP4@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
IHAFMDNN_02214	622312.ROSEINA2194_01216	4.61e-289	799.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia	186801|Clostridia	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
IHAFMDNN_02215	622312.ROSEINA2194_00341	0.0	943.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
IHAFMDNN_02216	411463.EUBVEN_02693	3.25e-128	367.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
IHAFMDNN_02217	585394.RHOM_14685	8.34e-38	127.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
IHAFMDNN_02218	411463.EUBVEN_02695	5.02e-62	196.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
IHAFMDNN_02219	622312.ROSEINA2194_02212	1.64e-62	197.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
IHAFMDNN_02220	622312.ROSEINA2194_02211	0.0	876.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
IHAFMDNN_02221	585394.RHOM_14665	4.36e-175	492.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
IHAFMDNN_02222	585394.RHOM_14660	0.0	871.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
IHAFMDNN_02223	585394.RHOM_14655	1.05e-77	233.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
IHAFMDNN_02224	658086.HMPREF0994_01674	5.6e-67	218.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V41T@1239|Firmicutes,25B4Q@186801|Clostridia,27TZT@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
IHAFMDNN_02225	397291.C804_03759	0.0	1059.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
IHAFMDNN_02230	411490.ANACAC_00800	7.53e-40	145.0	2DMT9@1|root,32TI5@2|Bacteria,1VCAH@1239|Firmicutes,24N04@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02231	1118057.CAGX01000020_gene1647	8.97e-14	70.9	COG4570@1|root,COG4570@2|Bacteria,1VFJ9@1239|Firmicutes,24NSB@186801|Clostridia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC	-	-	-	-	-	-	-	-	-	-	-	-	RusA
IHAFMDNN_02232	411490.ANACAC_00813	7.23e-69	218.0	COG3617@1|root,COG3617@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ANT,Bro-N
IHAFMDNN_02234	1304866.K413DRAFT_3016	3.19e-146	417.0	COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,24CGP@186801|Clostridia,36RWZ@31979|Clostridiaceae	186801|Clostridia	L	PDDEXK-like domain of unknown function (DUF3799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3799
IHAFMDNN_02235	1304866.K413DRAFT_3015	1.3e-131	380.0	28KIJ@1|root,2ZA3S@2|Bacteria,1TSCG@1239|Firmicutes,24DNK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02236	742733.HMPREF9469_01850	3.25e-209	593.0	COG0497@1|root,COG0497@2|Bacteria,1V4D8@1239|Firmicutes,24FMH@186801|Clostridia	186801|Clostridia	L	DNA recombination	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
IHAFMDNN_02240	742740.HMPREF9474_03484	3.46e-15	70.1	2EUTV@1|root,33N9D@2|Bacteria,1VPRB@1239|Firmicutes,24X69@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02241	1280692.AUJL01000009_gene2978	0.000364	42.7	2A6DU@1|root,30V6Q@2|Bacteria,1UQU9@1239|Firmicutes,24UXG@186801|Clostridia,36P9I@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02245	1321814.HMPREF9089_00909	9.75e-14	66.2	29VDH@1|root,30GU7@2|Bacteria,1UGNJ@1239|Firmicutes,25P5Q@186801|Clostridia,25Z4C@186806|Eubacteriaceae	186801|Clostridia	S	Helix-turn-helix domain of resolvase	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02246	483218.BACPEC_01181	1.69e-30	114.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,26BI8@186813|unclassified Clostridiales	186801|Clostridia	K	Peptidase S24-like	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_19,HTH_3,Peptidase_S24
IHAFMDNN_02247	1347392.CCEZ01000005_gene1204	1.21e-51	168.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,36JH7@31979|Clostridiaceae	186801|Clostridia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
IHAFMDNN_02248	585394.RHOM_05930	1.12e-167	485.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
IHAFMDNN_02249	411459.RUMOBE_02138	2.31e-43	155.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,3XZSV@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
IHAFMDNN_02250	428125.CLOLEP_01728	0.0	1310.0	COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,24B3G@186801|Clostridia,3WN9G@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
IHAFMDNN_02251	515620.EUBELI_00659	3.48e-239	669.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
IHAFMDNN_02252	350688.Clos_2061	1.42e-25	112.0	28NDR@1|root,2ZBGG@2|Bacteria,1TSYU@1239|Firmicutes,24E7Y@186801|Clostridia,36PP2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02253	411490.ANACAC_02200	0.0	1115.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia	186801|Clostridia	J	Elongation factor	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
IHAFMDNN_02254	585394.RHOM_05940	4.24e-24	93.6	2EHJU@1|root,33BBQ@2|Bacteria,1VN8N@1239|Firmicutes,24VAU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02255	585394.RHOM_16015	4.16e-73	226.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24F4A@186801|Clostridia	186801|Clostridia	G	phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
IHAFMDNN_02256	622312.ROSEINA2194_04378	7.34e-138	394.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
IHAFMDNN_02257	622312.ROSEINA2194_04379	9.34e-177	497.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
IHAFMDNN_02258	622312.ROSEINA2194_04380	0.0	998.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia	186801|Clostridia	G	Phosphotransferase System	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
IHAFMDNN_02259	140626.JHWB01000022_gene2043	3.49e-35	121.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
IHAFMDNN_02260	140626.JHWB01000022_gene2044	2.69e-293	812.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
IHAFMDNN_02261	585394.RHOM_15990	1.85e-232	647.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
IHAFMDNN_02262	585394.RHOM_00600	6.04e-90	277.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24HJP@186801|Clostridia	186801|Clostridia	V	vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_2,VanW
IHAFMDNN_02263	622312.ROSEINA2194_01363	1.42e-245	674.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
IHAFMDNN_02264	585394.RHOM_08065	7.35e-104	302.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia	186801|Clostridia	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
IHAFMDNN_02266	585394.RHOM_08080	2.62e-287	811.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
IHAFMDNN_02267	585394.RHOM_08085	1.44e-46	156.0	COG1511@1|root,COG1511@2|Bacteria,1VFYY@1239|Firmicutes,24RU2@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02268	585394.RHOM_08090	7.44e-273	777.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
IHAFMDNN_02269	1226322.HMPREF1545_00232	1.46e-43	147.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,2N7F0@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02270	622312.ROSEINA2194_04170	9.87e-188	535.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IHAFMDNN_02271	1410612.JNKO01000036_gene194	6.9e-69	224.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,2PS4Q@265975|Oribacterium	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
IHAFMDNN_02272	585394.RHOM_08555	3.74e-36	130.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
IHAFMDNN_02273	585394.RHOM_01085	1.04e-201	561.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia	186801|Clostridia	S	domain protein	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
IHAFMDNN_02274	585394.RHOM_01080	1.42e-180	521.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
IHAFMDNN_02275	585394.RHOM_01075	0.0	1193.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
IHAFMDNN_02276	622312.ROSEINA2194_02099	7.05e-154	433.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_02277	585394.RHOM_01065	3.33e-274	758.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
IHAFMDNN_02278	1235798.C817_01435	7.68e-54	175.0	2EAJ6@1|root,334N3@2|Bacteria,1VFXU@1239|Firmicutes,24RPH@186801|Clostridia	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	ko:K19167	-	-	-	-	ko00000,ko02048	-	-	-	ToxN_toxin
IHAFMDNN_02279	585394.RHOM_08800	1.62e-155	458.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_8
IHAFMDNN_02280	585394.RHOM_08805	5.79e-162	468.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia	186801|Clostridia	T	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
IHAFMDNN_02281	585394.RHOM_08810	7.57e-240	678.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
IHAFMDNN_02282	622312.ROSEINA2194_02741	1.05e-80	241.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
IHAFMDNN_02283	622312.ROSEINA2194_02742	4.85e-138	398.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
IHAFMDNN_02284	622312.ROSEINA2194_02743	4.52e-156	442.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
IHAFMDNN_02285	585394.RHOM_08830	0.0	1059.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
IHAFMDNN_02286	585394.RHOM_08835	5.23e-162	459.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
IHAFMDNN_02287	483218.BACPEC_01341	1.19e-200	559.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,267UI@186813|unclassified Clostridiales	186801|Clostridia	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
IHAFMDNN_02288	1235790.C805_02147	1.35e-12	67.4	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
IHAFMDNN_02289	585394.RHOM_00400	0.0	902.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
IHAFMDNN_02290	622312.ROSEINA2194_04402	8.01e-127	365.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia	186801|Clostridia	T	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
IHAFMDNN_02291	585394.RHOM_00410	6.42e-217	610.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
IHAFMDNN_02292	585394.RHOM_00425	0.0	1633.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
IHAFMDNN_02293	585394.RHOM_00435	4.15e-103	301.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
IHAFMDNN_02294	585394.RHOM_00440	3.24e-150	431.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
IHAFMDNN_02295	585394.RHOM_02465	0.0	1093.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
IHAFMDNN_02296	585394.RHOM_02470	0.0	1096.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
IHAFMDNN_02297	585394.RHOM_02475	2.69e-207	575.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
IHAFMDNN_02298	585394.RHOM_02480	5.27e-300	822.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
IHAFMDNN_02299	585394.RHOM_02485	3.53e-137	397.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
IHAFMDNN_02300	585394.RHOM_02490	4.44e-179	502.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
IHAFMDNN_02301	622312.ROSEINA2194_03472	1.22e-144	415.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
IHAFMDNN_02302	585394.RHOM_06250	1.61e-152	436.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia	186801|Clostridia	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
IHAFMDNN_02303	585394.RHOM_06255	7.54e-40	132.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
IHAFMDNN_02304	622312.ROSEINA2194_02811	0.0	1394.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes	1239|Firmicutes	S	Peptidase M16 inactive domain protein	hypA2	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
IHAFMDNN_02305	622312.ROSEINA2194_02810	5.89e-203	563.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
IHAFMDNN_02307	585394.RHOM_06275	3.65e-125	362.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
IHAFMDNN_02308	585394.RHOM_06280	1.05e-85	262.0	2BFV8@1|root,329QI@2|Bacteria,1V7DP@1239|Firmicutes,24KD4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02309	585394.RHOM_06285	0.0	958.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
IHAFMDNN_02310	585394.RHOM_00680	1.79e-209	587.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,249U5@186801|Clostridia	186801|Clostridia	P	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
IHAFMDNN_02311	585394.RHOM_00685	2.37e-194	549.0	COG4641@1|root,COG4641@2|Bacteria,1TS28@1239|Firmicutes,24E2J@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
IHAFMDNN_02312	1410632.JHWW01000012_gene81	2.65e-60	202.0	COG1215@1|root,COG1215@2|Bacteria,1VRTD@1239|Firmicutes,24BW4@186801|Clostridia,27IRS@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_02313	585394.RHOM_00715	4.67e-187	541.0	COG0438@1|root,COG0438@2|Bacteria,1V5AP@1239|Firmicutes,24GJ0@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
IHAFMDNN_02314	1410630.JNKP01000001_gene2217	4.61e-62	203.0	COG0463@1|root,COG0463@2|Bacteria,1UI7F@1239|Firmicutes	1239|Firmicutes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
IHAFMDNN_02315	585394.RHOM_00730	6.95e-188	545.0	COG4641@1|root,COG4641@2|Bacteria,1UMWB@1239|Firmicutes,24CQX@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
IHAFMDNN_02316	622312.ROSEINA2194_00395	8.67e-52	166.0	2C12Y@1|root,32STC@2|Bacteria,1VCPE@1239|Firmicutes,24Q1P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02317	622312.ROSEINA2194_00398	3.27e-183	520.0	COG4641@1|root,COG4641@2|Bacteria,1V3QP@1239|Firmicutes,24I06@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2
IHAFMDNN_02318	585394.RHOM_04475	3.61e-129	374.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
IHAFMDNN_02319	585394.RHOM_04470	1.23e-183	519.0	28JB6@1|root,2Z960@2|Bacteria,1U83T@1239|Firmicutes,24BAY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02320	585394.RHOM_04465	2.95e-101	295.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia	186801|Clostridia	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
IHAFMDNN_02321	585394.RHOM_04460	0.0	1077.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
IHAFMDNN_02322	585394.RHOM_04455	1.56e-194	543.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
IHAFMDNN_02323	585394.RHOM_04450	5.97e-98	286.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
IHAFMDNN_02324	585394.RHOM_04440	2.66e-30	108.0	2DRX4@1|root,33DGR@2|Bacteria,1VKQ3@1239|Firmicutes,24URP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02325	585394.RHOM_04435	1.04e-66	206.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02326	1469948.JPNB01000001_gene446	4.12e-143	444.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
IHAFMDNN_02327	585394.RHOM_03080	5.67e-217	605.0	COG1638@1|root,COG1638@2|Bacteria,1TSSW@1239|Firmicutes,24DW9@186801|Clostridia	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
IHAFMDNN_02328	585394.RHOM_09690	3.36e-185	520.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
IHAFMDNN_02329	585394.RHOM_09685	8.88e-220	611.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
IHAFMDNN_02330	585394.RHOM_09675	0.0	1204.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia	186801|Clostridia	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
IHAFMDNN_02331	622312.ROSEINA2194_00090	0.0	1267.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia	186801|Clostridia	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
IHAFMDNN_02332	622312.ROSEINA2194_00096	2.34e-96	290.0	COG1266@1|root,COG1266@2|Bacteria,1V7EK@1239|Firmicutes,24KV5@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
IHAFMDNN_02333	411459.RUMOBE_02187	6.91e-52	168.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,3Y0CK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
IHAFMDNN_02335	33035.JPJF01000073_gene4424	3.1e-19	85.9	COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia,3Y0DC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02336	411462.DORLON_00146	9.01e-29	109.0	COG2364@1|root,COG2364@2|Bacteria,1V19X@1239|Firmicutes,24DJ8@186801|Clostridia,27VXU@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02337	585394.RHOM_05010	2.38e-45	148.0	2EK04@1|root,33DQP@2|Bacteria,1VM4D@1239|Firmicutes,24WYN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02338	585394.RHOM_05425	1.61e-139	398.0	28XBK@1|root,2ZJ9G@2|Bacteria,1V203@1239|Firmicutes,24E0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
IHAFMDNN_02339	622312.ROSEINA2194_02644	1.52e-77	241.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
## 2131 queries scanned
## Total time (seconds): 335.02473640441895
## Rate: 6.36 q/s