LOCUS       c00058_gnlPro..        13401 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BPJOPFFH_58.
ACCESSION   c00058_gnlPro..
VERSION     c00058_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:40:40
            Original ID  :: gnl|Prokka|BPJOPFFH_58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4847
            Orig. end    :: 18248
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13401
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[14847:18246](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13399)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13401
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13401
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             625..1791
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 112.6; E-value: 6.3e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_5"
                     /sec_met_domain="MFS_1 (E-value: 1.3e-35, bitscore: 112.6,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNNSYMKLIPVMLCFFAMGFVDLVGIASNYVKADLGLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDSYLLMLVSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASTLTFGQFVKAIASFLAPYIAMWGAIEAIPT
                     FDLGWRVLFPIYMVVAVVAILLLNATQITEEPEEGKPSTFGQCLALLGKPFILLSFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAAKTF
                     FAISVLCMLAAMFGLFVFQDQAMIYVCIALIGFGNSNVFPIIFSQAMLYMPDKKNEVSG
                     LMIMGLFGGTIFPLAMGVASDAVGQSGAVAVMLVGVLYLMFYTWRIKK"
     CDS             1823..2713
                     /locus_tag="ctg58_6"
                     /transl_table=11
                     /translation="MNSIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGNDELGDEILEIFREKQLKHQLERVNYPTGTVQVTLDNGGVPCYDIKEGVAWDNIPFT
                     DDLKRLALSTRAVCFGSLAQRDEVSRATINRFLDTMPDMEGQLKIFDINLRQNFYTKEV
                     LRESFRKCNVLKINDEELIIISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGTVSFQETPKVPVADTVGAGDSFTAAFCSSVLKGKSIPEAHRLAVEVSAYVCTQSG
                     AMPVLPEALRNRLND"
     CDS             2897..5620
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_7"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.3e-15, bitscore:
                     46.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRILFLLGLMLSGLLVSCSPDAPRYTIGVSQCSDDTWRHKMNDE
                     IQREALFYGGVKVETRTAHDDSRRQIEDIRYFIRQKVDLLIVAANEGMALTPVVEEAFD
                     KGIPVIMVDRRILSDKYTAYIGADNYELGKAVGNYIAHRLKGRGKVVELSGLVGSTPAI
                     ERHQGFMSVISQYPDMTLLASEDAGWLQQPAEAKMDSLLQRFPEIDAVYGMNDRMAAGA
                     FRAAGRRGREKEMIFVGIDALPGKGNGVELVLDSVLDATFIYPTEGDKVVQLAMDILEK
                     KPFERETKLKTAVVDAVNAHVMELQTNHIGELDGKIETLNDRVGIYLSRVATQRIVLYG
                     GLIILLLIVGLLIVVYKSLRSKNRLNRELSRQKEQLEEQRDQLIELSHQLEEATHAKLV
                     FFTNISHDFRTPLTLVADPVEQLLADPSLEGDRRRMLLLVQRNVQILLRLVNQILDFRR
                     YETGKMEFTPVPLDLLQCFVEWNDSFQAAARRKHIHFSFDSMPDTDYHTQADAEKLERI
                     YFNLLANAFKFTPENGKVTVRLATLKKDSVPFFRFTVANTGSLISAEHIRSIFDRFYKI
                     DRHHTGSGIGLALVKAFVEIHGGSISVESDERLGTVFTVDLPVRTCEEGTYVVTAPMEE
                     SAPDRVDSLLREDEVENLNDPSKPSVLVIDDNADIRAYVHTLLNSEYSIIEAADGTEGI
                     RKAMKYVPDVIISDVMMPGIDGIECCRRLKGELQTCHIPVILLTACSLDEQRIQGYAGG
                     ADSYISKPFSSQLLLTRIRNLIESRQRMKQFFGDRQTLAKEDICDMDKDFVERFKSLIE
                     VKMGDSELNVEDLGKEMGLSRVQLYRKIKSLTNYAPNELLRMARLKKAASLLASSDMTI
                     AEVGYEVGFTSPSYFAKCYKEQFGESPTEFLKRSGL"
     CDS             5651..5995
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MKDYKENKSNLSETFCNEVYSVVREIPAGSVTTYGDIAALLGMPQ
                     YSRMVGRALRQVPASLNLPCHRVVNAIGRLVPGWDEQRRLLDAEGVSFRKNGCVDLRLH
                     RWRDDSVLAD"
     CDS             6330..7556
                     /locus_tag="ctg58_9"
                     /transl_table=11
                     /translation="MSKITIKDLYLIFGNDKQHALRMLKEEKSKSEILKATGCTVAVKD
                     ANLSIREGEIFVIMGLSGSGKSTLLRCINRLIKPTSGEVIINGRDISNVTDKELLRIRR
                     KELAMVFQHFGLLPHRSVLHNIAFGLELQGVKKQEREQRAMESMQLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANDPEVLLMDEAFSALDPLIRIQMQDELLTLQSKMKKTIVFITH
                     DLNEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANAYVERFVQSVDRSKIITAASVMVD
                     KPLVARLKKEGPEVLIRKMLERNLTVLPVVDANNVLVGEVRLKDLLRLRQDQVKSIESV
                     VREEVHSVLGDTILEDILPLMTKTNSPIWVVNETREFQGVVPLSSLIYEVTGKNKQEIN
                     EIIQNAIEL"
     CDS             7553..8377
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 96; E-value: 7.4e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_10"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-30, bitscore:
                     96.0, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETLINWMMIHFSTFFDALNLGIGSFINGFQHILFGIP
                     FYLTIAAMVLLAWAKAGRGVAVFTLLGLLLIYGMGFWEATMQTLALVLSSTCLALIVGV
                     PIGVWTANSNRAEKVIHPILDLMQTMPAFVYLIPAVLFFGLGVVPGVFATIIFAMPPVI
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMVRRKDKK"
     CDS             8424..9251
                     /locus_tag="ctg58_11"
                     /transl_table=11
                     /translation="LLLLAVMCVACNPDSGKKKISIAYANWLEGIAMSHLAKVVLEEKG
                     YEVELLNADVAPVFASVSRKKADVFMDAWLPVTMKDYIDQYGDQIEFIGEVYDSARVGL
                     VVPQYVTIDSIGELAAHKGQFSSEIVGIDAGAGIMKTTDKAIGDYGLDGYKLLTSSSST
                     MLASLQKAMEKEAWIVITGWTPHWMFDRYPLKFLHDPKGTYGNVESIYVVGWKGFTEKD
                     PFAAKFFSNIKFTTEEISSLMKALKDARMDEEDLVRKWRDEHRELVESWIPES"
     CDS             complement(9293..9796)
                     /locus_tag="ctg58_12"
                     /transl_table=11
                     /translation="MNITIRPTRLEELGQVMPFYERARRFMAANGNANQWINGYPSPDD
                     IRQDIENGSSYVFVNENQELEGCFAFIRGEDPNYKVIKDGAWLNDAPYGVIHRIASGGR
                     VKGLMDLCLEWCSSHCPNLRVDTHRDNKVLQNILLKNGFTYCGIIYVKNGTERLAYQRT
                     AVTR"
     CDS             complement(10001..13399)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_13"
                     /sec_met_domain="PFOR_II (E-value: 1.6e-19, bitscore: 60.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.5e-70, bitscore: 226.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.7e-32, bitscore: 102.0,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.8e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.2e-08, bitscore: 22.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-05, bitscore: 14.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 5.1e-26, bitscore: 80.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMI
                     PNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLA
                     GVAHLATIKARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLVDQEALAEFRARALNPMN
                     PVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAER
                     VIIAMGSVTEAAREAIDYLTSQGEKVGLVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRT
                     KEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIIAVFKNLAMPMPKNH
                     FTIGIVDDVTFTSLPQEAEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHC
                     QAYFSYDSKKSGGFTCSHLRFGDDPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNG
                     SFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYINATQIAQEIGLGNRTNTILQSAFF
                     RITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDD
                     AKVENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWN
                     AENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCL
                     GCGNCADICPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQ
                     FATPLFEFSGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKG
                     HGPAWANSLFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNM
                     LDAEKTKELAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGL
                     DHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYG
                     YVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVK
                     CGYWHLWRYNPALEAEGKNPFTLDSKEPNWDDFKGFLKGEVRYASVMKQYPAEAEELFQ
                     AAEDNAKWRYNNYKRLANQAWGAAE"
ORIGIN
        1 tatacacaag atggggatat ctatatggct gccgccccgg tggaagagac caagtcattg
       61 cgtaaagaat cccgggagat tccggctttt gaggtggggg atgcttatca tgtcgattcg
      121 ttgttgtccg ataataaagg ggcttacgaa atagagttgg aactggcagc cggctctgcc
      181 gagattatgg gactgaagct gttcaatgaa aaaggggaga atgtggatat ctacatcagc
      241 cttccggaga aaaagttggt gatggaccgt acgaagagcg gcatcgtaga cttcggcaaa
      301 gacagtgccc cgcatgccat cgaggcacac gatcgccgga aacagaactc tattaattat
      361 gtagacgatt ttgctttggg tacctgggct ccggtgcaga aagccggtaa ctataaattg
      421 gatatctttg tagataaatg ctcggtagaa atcttcctga acggaggtaa gattgctatg
      481 acgaacctga tattccctac aactccttac aatcagatga gtttctacag tcgtggggga
      541 gccttcaagg tggatcggtg caagatatac aggttgtagt tcctctatcg cctcccgttg
      601 agacattcat taaattaaca tatcatggaa aataccaaaa acaactctta catgaaactc
      661 atcccggtga tgctctgctt ctttgccatg ggattcgtag atctggtggg cattgcctcc
      721 aactacgtca aagcagattt gggactgacg gactcacagg caaacatctt tccgtcgctc
      781 gttttcttct ggtttctgat cttctctgta cctacgggga tgctgatgaa ccgcatcggg
      841 cgtaaaaaga ccgtgttgct cagcctggtg atcactttcg catcattact gctaccggtc
      901 tttggtgata gctatttgct gatgttggtc tctttctcgt tgctcggcat tggcaatgcg
      961 ttgatgcaga catcgctcaa tccgttgctg tcgaatatcg tgagcggcga gcgcttggca
     1021 agtaccctga ccttcgggca gtttgtaaag gccatcgcct ccttcctagc cccttatatc
     1081 gctatgtggg gagcgatcga ggccatccct accttcgact taggctggag agtgctgttc
     1141 cccatctata tggtggtggc tgtagtcgct attttgttgc tcaacgccac gcagatcacc
     1201 gaagagccgg aagagggcaa accttccact ttcggtcagt gtctcgcttt gctgggtaaa
     1261 cccttcattc tgctctcgtt tttgggcatt atgtgtcatg tggggatcga tgtgggtacc
     1321 aatactacag caccgaagat tctgatggaa cgtctgggca tgactctggc ggatgccggg
     1381 tttgcgacca gtctttactt cattttccgt acggcaggtt gttttctggg agctttcatt
     1441 ttgcagaaga tggcggctaa aaccttcttc gctatcagtg tgttgtgtat gctggccgcc
     1501 atgttcgggt tgttcgtttt ccaggaccag gcgatgattt atgtctgtat tgccctgatc
     1561 ggatttggca actctaatgt attccccatc attttctcgc aggcaatgct ctatatgccg
     1621 gacaagaaga acgaggtttc cggcctgatg attatgggac ttttcggtgg aacgatcttc
     1681 ccgctggcaa tgggagtggc ttcggatgct gtgggacaaa gcggagcggt agcggtgatg
     1741 ctggtcggag tactctatct gatgttttat acatggagaa tcaagaaata accggattta
     1801 tagataaaaa ttaattcata ccatgaacag tataatcgta ggaatgggcg aagcgctatg
     1861 ggatgtgctg cccgaaggaa agaaaatcgg gggagccccg gctaattttg cttatcatgt
     1921 gtctcagttt ggtttcgaca gccgcgttgt cagtgcggta ggaaatgacg aactgggtga
     1981 cgagattctg gaaatattcc gggagaaaca gttgaagcac cagctcgaaa gggtgaacta
     2041 cccgaccgga acggtacagg tgactctcga taacggcgga gtgccgtgtt atgacatcaa
     2101 agagggagtg gcatgggata atattccttt cacagacgac ttgaaacggc tggctttgag
     2161 tacacgtgct gtctgtttcg gttcgttggc acagcgcgat gaggtgagcc gtgccactat
     2221 caaccgcttc ctcgacacca tgcccgacat ggaaggacag ttgaaaatat tcgatatcaa
     2281 ccttcgtcag aacttctaca ccaaggaggt cttgcgtgaa tctttccgga agtgcaatgt
     2341 gctgaagatt aatgatgagg aattgatcat tatcagccgc atgttcggtt atcccggcat
     2401 cgacctgcag gataaatgtt ggattctgct ggccaagtat aacctgaaga tgctgatcct
     2461 gacttgcgga acgaacggaa gttatgtatt cactcccggt acggtctctt tccaggagac
     2521 accgaaagtt ccggttgccg atactgtggg ggcgggtgat tcgtttacag cggctttttg
     2581 ttcatctgtt ttaaaaggaa agagtatccc tgaggcacat cggctggcgg tagaggtatc
     2641 tgcttacgta tgtacccaaa gtggagcgat gcccgtactt ccggaggctt tgaggaatcg
     2701 tttgaatgac taatgtgttg gtttatatag ggttattgat tggttaatag aaagttccgt
     2761 tgggtttaga atcaggagag tgtttcataa ctcacctttt aaaccaacgg gactttggtt
     2821 ttaaaccaag caggtgggag attccggagg gaaattgtta tatttgcctc cggaaccttt
     2881 tatgtaataa ccgaccatga gccgtatact tttcttactc ggactgatgc tgtcgggact
     2941 gcttgtctcg tgcagtccgg atgctccccg atataccatc ggtgtgtcac aatgcagtga
     3001 cgacacctgg cgtcacaaga tgaatgacga gatacagcgg gaagccttgt tctacggagg
     3061 agtcaaagta gagacacgta cggcgcatga cgatagccgg cgtcagatag aagacatacg
     3121 atacttcatc cggcagaagg ttgacctgct gattgtagca gccaatgaag gaatggctct
     3181 cactccggtt gtcgaggagg ctttcgataa aggaataccg gtgattatgg tagaccgcag
     3241 aatactttcc gataaatata ccgcatacat cggagccgac aattatgagt tgggcaaagc
     3301 cgtcggcaat tacatagccc atcgcctgaa agggcgcgga aaagtagtcg aactgagcgg
     3361 acttgtcggt tctactcccg ctatcgagcg ccatcagggg tttatgagtg tcatcagcca
     3421 atatccggac atgaccttgc ttgccagcga agatgcagga tggctgcaac aacctgccga
     3481 ggcaaagatg gactcccttt tgcaacgttt tccggagatc gatgccgtat atggaatgaa
     3541 tgaccgtatg gctgcagggg cttttcgggc tgccggtcgt cgaggacggg agaaggagat
     3601 gatttttgtg ggcatcgatg ccctgccggg taaggggaat ggagtggaac tggtgctcga
     3661 cagcgtactg gatgccacct ttatctatcc caccgaaggg gataaagtgg tgcaactggc
     3721 aatggatatt ctcgaaaaga aaccttttga acgggaaacg aagttgaaga cggctgtagt
     3781 cgatgcggta aacgcgcatg tgatggagtt gcagacaaac catatcggtg agctggacgg
     3841 aaagatcgag acactgaacg accgtgtggg gatatatctc tcgagggtgg ctacgcaacg
     3901 gatagtgttg tacggaggtc tgatcatcct gctgctgatc gtcgggttgt tgatagtagt
     3961 atataaatcg cttcgttcca agaatcgcct gaaccgggag ctgtcacggc aaaaggagca
     4021 gttggaagag caaagagatc agctgatcga actttcccat cagttggaag aggctaccca
     4081 tgccaaactg gttttcttca ccaacatttc acatgatttc cgtactcctc tcactttggt
     4141 tgccgatcct gtggaacagc tactggcaga tccgtcgctg gaaggtgacc ggcgtagaat
     4201 gttgttgctg gtgcaacgca atgtgcagat cctattgcgt ctggtcaatc aaatacttga
     4261 ttttcgcaga tatgagaccg gaaaaatgga gtttacgccg gttccgctcg acctgttgca
     4321 atgctttgta gagtggaatg attcgtttca ggcggctgcc cggcggaaac atatccactt
     4381 ctctttcgac agtatgcccg atacggatta tcacacacag gcagatgcgg agaagctgga
     4441 acgcatttac ttcaatttgt tggcaaatgc ctttaaattc actccggaga atggaaaggt
     4501 cactgtccgt cttgcgactc tgaagaagga cagcgtgcct ttcttccgtt tcacggtggc
     4561 caataccggc agcctgattt cggctgaaca cattcgcagc attttcgatc ggttctataa
     4621 aatcgacagg catcataccg gttccggcat cgggttggca ttggtgaaag cattcgtcga
     4681 gatacatggc ggaagtatta gtgtggagag tgacgaacgg ttgggaactg tctttactgt
     4741 cgatctgccg gtgcggactt gtgaagaggg gacttatgtg gtgactgctc cgatggagga
     4801 gtctgctccg gaccgggtgg acagcctgct ccgcgaggat gaagtggaaa acctgaatga
     4861 tccgtccaaa ccttctgtcc ttgtgatcga cgataatgcc gacatccgtg cttatgtgca
     4921 tacgttgctc aattcggagt attcgattat tgaagctgcg gatggtaccg aaggaatccg
     4981 taaagcgatg aagtacgtcc ccgatgtgat tatttcggat gtgatgatgc cggggatcga
     5041 tggcatagag tgttgtcgga ggctgaaggg agaactgcaa acctgccaca ttcccgttat
     5101 cctgcttacg gcctgttcgc tcgatgagca acgcatccag ggatatgcgg gaggagccga
     5161 ttcatacatc tcaaagccgt tcagttcgca actcttgttg acccgtatcc gaaatctgat
     5221 tgaatcgcgg cagcgtatga agcagttctt tggcgaccgg cagacgctgg cgaaagaaga
     5281 catttgcgat atggataaag attttgtgga gaggttcaag tcgctgatcg aggtgaagat
     5341 gggtgattcg gaacttaatg tggaagatct gggcaaggag atggggttga gccgggttca
     5401 gctttatcgg aagatcaagt cgctcacgaa ctacgctccc aatgagctgc tccgcatggc
     5461 acgtcttaaa aaggcggcat ctctgttggc ttcttcggat atgacgatag cggaggtcgg
     5521 atatgaagtg ggattcacat ctccttcgta ctttgcgaag tgttacaagg agcagttcgg
     5581 tgaaagtccg acggagttcc tgaagagaag cggattataa aggaactcac tgtataaaag
     5641 caatacatcc atgaaagatt ataaagaaaa taaatctaat ttgtccgaaa ctttttgtaa
     5701 tgaagtatac agtgtcgtgc gtgagattcc tgccggtagt gttactactt atggcgatat
     5761 tgccgctttg ctcgggatgc cgcaatattc acgcatggtg gggcgtgcct tgaggcaggt
     5821 gcctgccagt ttaaacctcc cttgtcatcg ggtagtcaat gccataggcc gattagtgcc
     5881 cggatgggac gagcagcggc ggctgctgga tgccgaaggt gtttctttcc gtaaaaatgg
     5941 atgtgtagac ctcaggcttc acaggtggag ggatgacagt gtgctggccg attgatacag
     6001 actctcttgt aggggtttat gtacgtgtaa tgcgcctgcc ggaaataatg cgatgaacca
     6061 tttgaacgtt cggcttgttt acttaattgt ctgcatacgc atctttggaa gatagctgtg
     6121 tgcggatgtg aaattgactt tcgggatata gtaaactatc tgttgacagg aatcctgtct
     6181 gtaataatcg ggtaaagaaa tcatatttga ccggggaacg gcggaaccgt cgcttccccg
     6241 gcattaactt ccttgctata aagaagtgct tgttttcgtg tgtataggtc acccgatctg
     6301 tttttttaat aatctaaacc ctattatgta tgagtaaaat aacgattaaa gacttgtatc
     6361 tcatttttgg caatgacaaa cagcatgctt tacgcatgtt gaaggaagaa aagagcaaaa
     6421 gtgagatatt gaaggctacc ggatgtacgg tggccgtaaa agatgcaaac ctatctatca
     6481 gggaaggaga aatatttgtg attatgggac tttcgggaag tggaaaatca actttgctgc
     6541 gttgcatcaa ccgattgata aaaccgacct cgggcgaagt gatcattaac gggagagata
     6601 tttctaacgt cactgataaa gaattgctcc gtatccgaag aaaagaactg gctatggtgt
     6661 tccagcattt tgggttgttg ccccatcgct cggtgttgca taacatagct ttcggactgg
     6721 aactgcaagg agtaaagaaa caggagcggg agcagcgggc gatggaaagt atgcaactgg
     6781 taggactgaa gggctacgag aaccagatgg tcggcgaact gtcgggaggt atgcagcaac
     6841 gtgtcggttt ggcccgtgcg ttggccaatg atcctgaggt gctgctgatg gatgaggctt
     6901 tttccgctct cgatcctttg attcgcatac agatgcagga tgaattgctg accttacaat
     6961 ctaagatgaa gaagaccatt gtgtttatta cccacgattt gaatgaagcc attaaattgg
     7021 gcgaccggat tgctatcatg aaagatggtg aggtggtaca ggtaggcact tcggaagaga
     7081 tcctgacaga accggccaat gcttatgtag agcgctttgt gcagagtgtg gaccgtagca
     7141 agattattac cgctgcatca gtgatggtag ataaacccct tgtggcccga ttgaagaaag
     7201 agggaccgga ggtgttgatt cgtaaaatgc tcgagcgtaa cctgactgtg ttgcctgtgg
     7261 tcgatgcaaa caatgtgctt gtgggagagg tccggctgaa agatttgctc cgattgcgtc
     7321 aagaccaggt gaagtcgatc gagtcggttg tccgggagga agtgcattcg gtgttgggag
     7381 atacgatact ggaagatatt ttaccgttga tgacaaaaac caattcgcct atctgggtag
     7441 tgaacgagac ccgcgagttt cagggagttg ttccgttgtc atcgcttatt tatgaggtaa
     7501 ccggaaagaa caaacaagaa atcaatgaaa tcattcaaaa tgcaatagaa ttatgatcaa
     7561 cataggacaa tatattgaga cgctcatcaa ctggatgatg atacacttct ccactttttt
     7621 cgatgcactc aacttaggca tcggtagttt tattaatgga ttccagcaca tactgttcgg
     7681 cattcctttc tatctgacca ttgcggcaat ggtgctgctg gcatgggcga aggccggacg
     7741 cggtgttgca gttttcaccc ttttaggctt gttgcttatt tatggtatgg gattctggga
     7801 agccactatg cagacattgg cactggttct gtcatccacc tgcctggccc ttatcgtagg
     7861 ggttcccatc ggagtatgga cggcaaacag caatcgtgcc gagaaggtga tacatcccat
     7921 tctcgacctg atgcagacca tgccagcctt cgtctatctg attcctgctg ttttgttttt
     7981 cggcctggga gtggttccgg gagtatttgc tacaatcatc tttgcgatgc ctccggtgat
     8041 tcgccttaca gggcttggca tccgtcaggt gccaaagaat gtggtagagg cttcacgctc
     8101 gttcggagct acccgatggc agttgcttta taaagtacag ttgccccttg ctttgcccac
     8161 catcctgacc ggagtgaacc agacgattat gatgtctctt tccatggttg tcattgcggc
     8221 tatgattgct gccggcggtt taggagaaat cgttttgaaa ggtatcaccc agatgaaaat
     8281 cgggctgggc tttgaaggag gtatagccgt tgtcatattg gcaattattt tagaccggat
     8341 tactcaggga atggtccgtc ggaaggacaa aaaatagaaa ggagaaagaa taggatatgc
     8401 gaaaatatag aataatagga agtttgttgc tactggctgt gatgtgcgta gcctgtaacc
     8461 cggatagcgg gaaaaagaag ataagcattg cctatgccaa ctggctggaa ggaattgcca
     8521 tgagtcatct ggctaaagtg gtgctggaag agaaggggta cgaagtggag ttgctgaatg
     8581 cagatgtagc tcccgtcttt gcatcggttt cccgtaagaa ggcagatgtg tttatggatg
     8641 cctggttacc tgtgacaatg aaggattata tagatcaata cggtgatcag atagagttta
     8701 tcggagaggt atatgatagc gcgagggtag ggctggtggt acctcaatat gtcactatcg
     8761 attcgattgg ggaacttgcc gcccacaaag ggcagttctc ttccgagatt gtcgggatcg
     8821 atgccggagc cggtattatg aaaactaccg ataaggctat cggggattat ggtctcgatg
     8881 gttataaatt actcacctcg agcagctcta ctatgttggc ttctttgcag aaggctatgg
     8941 agaaggaggc gtggatcgtc atcaccggat ggactccgca ttggatgttc gatcgctatc
     9001 cattgaagtt cctgcatgat ccgaaaggta cttatgggaa tgtggaatct atctatgtcg
     9061 tcggatggaa aggatttacg gagaaagatc cttttgcggc aaagtttttc agcaatatta
     9121 aattcactac agaagagatt agttcgttga tgaaagcact taaagatgca cgcatggacg
     9181 aagaagatct tgtccgaaaa tggcgcgacg aacatcggga actggtagaa agctggatcc
     9241 ctgaatcata agcagtatat gtgtgtccgg gaatccaact tctgatttct gtctatcggg
     9301 taacggcagt gcgttggtag gcaagtcgtt ccgtaccgtt tttcacataa ataatgccac
     9361 aataggtgaa accgttctta aggagaatgt tttggagtac tttattgtca cggtgagtgt
     9421 ctacacgcag gttcggacag tgggacgaac accattccag gcataagtcc attaatccct
     9481 ttacccgtcc gccggatgcg atgcgatgga tcaccccgta aggggcatcg ttgagccagg
     9541 cgccgtcttt gatgactttg tagttgggat cttctccccg gatgaaagca aaacagcctt
     9601 ctaactcttg attttcgttt acaaacacat agctgctccc gttttcgata tcttgccgga
     9661 tatcatcagg ggaggggtat ccgttgatcc actggttggc attgccattg gcagccatga
     9721 agcggcgggc acgttcgtag aatggcatca cttggccgag ttcttcaagc cgggtggggc
     9781 gtatggttat attcatgatt attccgtttt ttttgggggg ggcaccacag attacacgga
     9841 ttaacacaga actcttaatc ctatatattg acgaagataa attattaatc tgtgttaatc
     9901 cgtgtaatct gtggtgaaac ctattcattt ttgttcaaaa agggggaaag aacctctttt
     9961 agtcccttcc cccttcgaaa gttattatct gatcaaagat ttattcagct gcaccccaag
    10021 cctggttagc cagacgcttg tagttgttgt aacgccattt tgcgttgtct tcagctgcct
    10081 ggaacagttc ttctgcttct gcaggatact gtttcataac tgatgcataa cgaacctcgc
    10141 ctttcaggaa gcctttgaag tcatcccaat tcggttcttt gctatccagc gtgaacggat
    10201 tcttgccttc tgcttccaga gccgggttgt aacgccacaa gtgccagtaa ccgcacttaa
    10261 cagctttttc ttcttcttcc tggctcttac ccataccggc tttcagaccg tggttgatac
    10321 atggagcgta agcgatgatc agtgatggtc ccggatatgc ttcagcttca cggatagctt
    10381 tcagagtctg agcctggtca gcacccatag caatctgagc aacatataca taaccgtaag
    10441 tagtagccat cagaccgagg tctttcttac gtacacgctt acctgcagca gcaaacttag
    10501 cgatagcgcc taccggagta gctttagaag actgaccacc tgtgttagag taaacctcag
    10561 tatccaatac aaggatgtta acgtccttac cggaagcgat tacatggtca agaccaccgt
    10621 aaccgatatc ataagaagca ccgtcaccac cgatgatcca ttggctgcgt ttaacaagat
    10681 attgttgcag atcagcgatt tgcttgcagt ggttgcattt atctttagca gcttctacca
    10741 tcggaatgat cttttcggcc agttccttag tcttttctgc atccagcata ttgttgatcc
    10801 attcagcaaa tacttctttg tattcagccg ggcagcaatc agaagcgata gcttcgttca
    10861 ttactttcac cagacgggca cgcatctttt cgttagccag ttccataccc agaccaaatt
    10921 cacagaagtc ttcgaacaag gagttagccc atgcaggacc gtgacccttt tcgttcatag
    10981 tgtacggagt agaaggaact gaaccggagt agatagaaga acatcctgta gcgttagcaa
    11041 ccatttcacg gtcaccgaac aactgagaaa tcagtttcac gtacggagtt tcaccacaac
    11101 cggagcaagc gcctgagaac tcaaacaacg gagttgcgaa ctgagagttc ttcacgttag
    11161 ccttgatgtc taccaggtgt tgtttgctct tcacgttttc agcgcagtaa gtccagttat
    11221 cagcttcggc caactggctt tcaaggtgtt tcatggtcaa tgccttgcca cccttcttcg
    11281 gattacccgg acagatgtcg gcacagttac cgcaacccag acaatcgaga acgtctacct
    11341 gaatacggaa tgtcatacca tcgaatgctt tacctacagc tttcagttgc tcgaacttag
    11401 cacccttctg ctcttcagca tcgagtacga acggacggat agaagcgtga ggacaaacgt
    11461 aagcacactt gttacactgg atacagtttt ctgcgttcca ttccggtacg aaagcagcta
    11521 caccgcgttt ttcgtattta gaagttccct gataccaggt tccgtcttcg atacctttga
    11581 atgcagatac cggcagtaag tctccgtcct gagcattgat agggcgaact acttcgttga
    11641 tgaatgccgg gtcgttgttt tcaaccttgg catcgtccgg caggttagcc caagccgggt
    11701 caacagtcaa agtcttgtat tcgccaccac ggtcaacggc tgcgtagttc ttgtttacaa
    11761 cgtcttcacc cttcttaccg taagacttca cgataaactt cttcatctgt tctacagcct
    11821 ggtctacagg gattacacct gtgatacgga agaatgcaga ctgaaggata gtattggtac
    11881 ggttgcccaa acctatttcc tgtgcaatct gagttgcgtt gatatagtat acagagatat
    11941 tgttctgtgc aaagtatttc ttcaccttgt taggcaggtt cttagccagc tcttcgcctt
    12001 cccagatagt gttcagcaag aacgaaccgt tcttacgcag accacgggtt acgtcgtaca
    12061 tgtgcaggta agcctgaacg tggcaagcca cgaagttcgg agtgtttacc agataggtag
    12121 aacggatagg atcgtcaccg aaacgcaggt gagagcaagt gaaacctcct gacttcttag
    12181 agtcgtaaga gaagtatgcc tgacagtgtt tatctgtgtt gtcaccgata attttcactg
    12241 agttcttgtt ggcacctact gtaccgtcag cacccaagcc gtagaattta gcttcgaaca
    12301 taccttcgcc acccagagcg atttctgctt cctgaggaag agaagtgaag gttacatcgt
    12361 ctacgatacc gattgtgaag tggttcttcg gcatcggcat agccagattc ttgaatacgg
    12421 cgatgatttg tgccggagta gtatctttag aacccagacc gtaacgaccg cctacgataa
    12481 ccggagcatt ttctgcgcca tagaagcagt ctttaacatc cagatacaga ggttcaccgt
    12541 tagcacccgg ttcttttgtg cgatcgagta ctgcgattgt tttagctgtt ttaggtacgg
    12601 cggccaggaa gtgtttagca gagaacgggc ggtacaggtg aactgcaacc aaaccgactt
    12661 tttctccttg gcttgtcaga tagtcgatag cttcgcgggc agcttctgtt acagaaccca
    12721 tagcgataat tacgcgttct gcatcttctg ctccgtagta atcgaacaaa ccgtatttgc
    12781 ggcctgtgat cttagaaatt tcattcatgt attcctctac gatggcggga acagcttcat
    12841 agtagttgtt gcatgattcg cggtgctgga agaagtggtc agggttttcg gccataccac
    12901 gggcaaccgg attcatcgga ttcagcgcac gtgcacggaa ttcggcaagc gcttcctggt
    12961 caaccaacgg agcgagatct tcattttcca gcatttcgat cttctggatt tcgtgtgaag
    13021 tacggaaacc atcgaagaag ttcatgaaag gaacacgggc tttgattgtg gcaaggtgtg
    13081 caacaccggc caagtccatc acttcctgta cagaaccttc agccaacata gcgaaacctg
    13141 tctggcgcgc agacattacg tcctggtggt caccgaaaat acacagtgcg tgagaagcca
    13201 gtgtacgagc agatacatgg aatacgcaag gcaggaattc accggcaatc ttatacatat
    13261 tcgggatcat caaaagaaga ccctgagaag cagtgtaagt agtagtcagt gcaccggcct
    13321 gaagagaacc gtgaacagca ccggctgcac caccttcaga ttgcatttcc tgtaccaata
    13381 ctgtttcgcc gaagatgttc t
//
