LOCUS       c00099_gnlPro..        13808 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BPJOPFFH_99.
ACCESSION   c00099_gnlPro..
VERSION     c00099_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:40:40
            Original ID  :: gnl|Prokka|BPJOPFFH_99
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13808
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13808
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9190:13808]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9191..13808
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..13808
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13808
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..701
                     /locus_tag="ctg99_1"
                     /transl_table=11
                     /translation="KSCIDSGFSSVMIDGSHLPYDENVALTKKVVEYAHQFDVTVEGEL
                     GVLAGVEDEVSSDHHTYTEPDEVVDFVTKTGCDSLAISIGTSHGAYKFTPEQCHIDPKT
                     GRMVPPPLAFDVLDGVMKELPGFPIVLHGSSSVPEEEVATINQFGGALKAAIGIPEEEL
                     RKATKSAVCKINIDSDSRLAMTAAIRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIIN
                     VLGSDNKLAE"
     CDS             complement(796..2391)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_2"
                     /sec_met_domain="MFS_1 (E-value: 7.1e-15, bitscore: 44.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKLNLPTRPWVPQWLGIVTMFIVIFPITLLNGAYTGSMVEVSNT
                     LGVLSEDITMAYYSASVGMAVAYPIVPKIRTIATPKTLLLTDLLLQIFFSLVCAKTGSM
                     DVIMVCSFCMGFLKAFVMLEFIILIRPLFSPKNVRSEFYAYFYPIVFSGGQLSMAITAQ
                     LAYHYQWQHMYYFVTILLLIAILFVICFFRYARRPMHIPFKEMDGRSMFIIATAFLLTL
                     YTFTYGKTLDWFASPKIRVYVFVIPLLIALFIHRQRTQGKPFVNLKPLFLHKSIIGYGF
                     MVLAMFLTATSSLVTNYMNSIIRVDSIHANSLSLWLLPGYVVGAVICFWWFRWQRWRFR
                     FLISGGMFCYVIYLAILYFGITPYGTYEMLYLPILFRGVGMMVIFIAFGVFVVEDLDPR
                     LTLSNAFFLISFRSVLAPVLSASFFNNMLYYLQAKGMNILSENMTLTNPLAEQKYNQAL
                     SNALAQGHEFGEAGQLAANSLYSTLQQQSLLLALKTLIGYVLILALVIAVIAAFIPFHK
                     TLKVAVVKTGDDMV"
     CDS             complement(2396..3463)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_3"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 2.6e-12,
                     bitscore: 36.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHQIKLKQLRRLKFRNIFLNTVCILLALAGISWTVNYFWKYAR
                     YEITNDAVVDQYIAPLNIRIPGYIKEVRFTEHQYVHAGDTLLILDDREYRIRLKDAEAA
                     LMDALGSKEVLNSGIRTSGVNVAVQEANIAETLARLSQQEAELNRYTRLLKKQAVSQQD
                     YELAKANFEATRARYNALLRQKEAAQSQYSETSKRSTGAEANILRKEADLEMARLNLSY
                     TVVTAPYDGYTGRRTLEPGQFVQGGQTLSYLVRGNDKWVTANYKETQIAHIYIGQKVRI
                     KVDAFSGRTFHGTVTAISEATGSKYSLVPTDNSAGNFVKVQQRIPVRIDLNDASPEEME
                     CLRAGMMVETEAVRP"
     CDS             complement(3476..3916)
                     /locus_tag="ctg99_4"
                     /transl_table=11
                     /translation="MTNNESERELVLQTLRTWMAFRQAVQRVLKRHNVDMTFEMLQVMN
                     CLWNKQGISQQSLAEKTAKDKACLTNLINNLEKKNWVIRKEGPSDRRNRLIFLTPQGEE
                     LALTVKPLINDIYAQTGTEMEASRITECIEDLKRLHEVLNEI"
     CDS             complement(4074..5924)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg99_5"
                     /sec_met_domain="Alpha-amylase (E-value: 6.5e-64, bitscore:
                     206.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLLLLGSFLLSLTTYAAMNISKIDPPFWFTGMNNPELQLMVY
                     GEGIGQASVSVNYPGVSLSSVVKLESNNYLLVYLHLDKEVKPGKMPITFTVGKKKLVKE
                     YELKARSKAGVDHKGFDASDALYLLMPDRFANGNPDNDRIEGMAEYKVDRNDPNARHGG
                     DLAGIEQNLDYFTDLGVTALWFTPVLENNMKGGSYHGYATTDYYKVDPRFGTNEEYRSL
                     IAKAHNRGIKVVMDMIFNHCGVEHPWIKDMPSKDWFNHADFKNNFVQTSYKLTPHVDPY
                     ASEYDFDQMNNGWFVEAMPDLNQKNPHVYKYLLQNSLWWIEYADIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPRNSHLKTVMDFSFFDKV
                     NTAKNEQTDTWFKGLDRVYNNFVYDYLYPNPASVLAFIENHDTDRFLGEGENLDMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWADDKENALTPEGRTRLQNE
                     SYNFYRNLLNWRKGNDVIAKGSMKQFMVQHGVYAYARQYKGKTVFVLLNGTDKEVKLPL
                     KYYAEVLKDKTQGKDVISGKVTALNEELTMAPRQSMVIEL"
     CDS             complement(6406..7698)
                     /locus_tag="ctg99_6"
                     /transl_table=11
                     /translation="MKHWILLLYLGFSVMLRAQNTASVQEAMANYDYKTVIRLIDEESA
                     SPQLLIQKAKALKGLGRTAEALSTLQHIIIELPENQQALVEAAECCRQLSKFNEALGYY
                     RKVMELNPEHIYAHLQYTRLLYNYQRYGDALRESIALARKDSSATVLRLMAESMEGAGM
                     PVESMFCYLSIIRKYPSDYLSVAKLGSIFNTMKDYEGAIALTEAYRRTDSTNVEVNRQN
                     ALAYCLRKEYPTAIKRYQDLTARGDSTLLTCYYLGVSYYATKEYYKARDWLLKAKSCQS
                     PGANLLYYLGRSCSKTLWKQEGIGYLNQAIALTIPADSIMERLYSGLADCYRQTKQTRD
                     QIKATKEQYKYAPDKHILLYNLAFLSDKIGDTKATEHYLQAFLRTKSKQNAVLQQPDND
                     EEEPAPYIDYYKSATNKLESIRKEKFLKGEK"
     CDS             complement(7711..9042)
                     /locus_tag="ctg99_7"
                     /transl_table=11
                     /translation="MRTRTMKPLFLIFCLCLSPLLMGQNQNKIQEAMANYDYETAVELI
                     NKEPPTIPLLMQKAKALKGIGSNAEALRSIRQVIAEDSTNQQAHIEAAECCKAMAKYND
                     ALDYYRKAISLNPKNKYARLQFINLLCNTKNYAEAFGESSMMSETDSSAVVLHLQAQSL
                     EGMQQILPAIGCYEVIQDKYPDDYLAAAKLGNLNIVAGYPEYAIQATERYRERDSTNLI
                     VNQQNALAYCHAEQYPTAIKRYEKLCQQGDSSTQTLYYLGVSYYADEYYYEAHACFSKL
                     QKEMEENPNLLYYLGRCCAKTSWKKEGIEHLEKAIELTIPKDSTMIRLYKGLVDCCKLA
                     QDTPKQIQALKELYKYDKTNHKLLYDIAWNYSYQLKDNKSAERYLQAFLKTRKANARKE
                     EPVSEKGELVLGLENYYNAAENWLKDLQKEKFFKEGIPLESQKQ"
     CDS             complement(9191..10351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_8"
                     /sec_met_domain="OAD_beta (E-value: 4.7e-154, bitscore:
                     502.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFVSFLGNNLVDFWGYTGFANATPGHLFMLLIGLFFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALLIGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRALTTKHERLIRMKPPRIVSHTEKVIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASQFLTWDSILIFILGAFSFIIATASGVMFVKFFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(10354..10785)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 69.7; E-value:
                     4.8e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_9"
                     /sec_met_domain="Biotin_lipoyl (E-value: 9.4e-23, bitscore:
                     69.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQYKYKINGNLYNVTVNDVEDNIANVEVNGTSYKVELDKPVKAA
                     PKPVTRPAAAPKTETGAPVVTKQPTASKKDGVKSPLPGVILDIKVKEGDTVKRGQTIII
                     LEAMKMENNINANKDGKVAEIKVNKGDSVLEGTDLVIIE"
     CDS             complement(10811..11725)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_10"
                     /sec_met_domain="OAD_gamma (E-value: 1.5e-16, bitscore:
                     50.6, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKRIGIFIALLAMVCMGLRAQSATSLRINEVLVVNDQNYQDDY
                     GLHNAWIEIFNTSFASVNLEGCFLTNDKNNPTKYPIPKGDVLTLIKPRQHALFWADGMP
                     NRGTFHVNFTLDPNKENYIALYDSNGKTLIDEVTIPAGQLADRSYAREKDGSANWVVKG
                     EGEHSYVTPSTNNMTIDKNPKIENFKKHDSIGIGMAIIAMSVVFIGLVLLYLSFKAVGN
                     VAVRLGKKNAMKATGITDKTEAKEKNLGSHTGEETAAIAMALHEYLNDAHDVEDMILTI
                     NKVKRTYSPWSSKIYTLRQTPKR"
     CDS             complement(11746..13299)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_11"
                     /sec_met_domain="CT_Btheta (E-value: 1.6e-291, bitscore:
                     956.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIELRAQARLGGGEKAIEKQHAKGKYTARERIAQL
                     LDEGSFEELDMFVQHRCTNFGQEKKHFLGDGVVTGYGTIEGRLVYVFAQDFTVFGGSLS
                     ETMAQKICKVMDMAMKMGAPVIGINDSGGARIQEGINALSGYAEIFQRNIMASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMTEGTSYMFLTGPAVVKTVTGEDVSQEDLGGASVHAS
                     KSGVTHFTAETSEEGLAIIRKLLSFIPQNNLEEAPLVNCTDPIDRMDDLLNEIIPDSPN
                     KPYDMYEVIGAIIDNGEFLEVQKDYAKNLIIGFARMNGQSVGVVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTV
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVAVLYAKEAKDQENPAQFLA
                     DKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(13425..13808)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg99_12"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4e-24, bitscore:
                     74.8, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDT
                     KIELLEPTCPESTIAKFIENKGAGVHHVAFAIEDGVANALAEAESKEIRLIDKAPRKGA
                     EGLNIAFLHPKSTLGVLTELCEH"
ORIGIN
        1 gcaagagctg tatcgactca ggtttctctt ctgtaatgat cgacggttct caccttcctt
       61 acgacgaaaa cgttgctctg actaagaaag ttgttgaata cgctcaccag ttcgatgtaa
      121 ctgtagaagg tgaacttggc gtattggcag gtgtagaaga cgaagtttct tctgaccacc
      181 acacatatac tgaaccggac gaagtagttg atttcgttac caagacaggt tgcgattcat
      241 tggctatctc tatcggtact tctcacggtg cttacaaatt tactccggaa cagtgccaca
      301 tcgatccgaa gacaggccgt atggttcctc ctccgttggc attcgacgta ttggacggtg
      361 taatgaaaga acttccggga ttccctatcg ttcttcacgg atcatcttca gttcctgaag
      421 aagaggttgc aactatcaac cagtttggtg gtgcactgaa agctgctatc ggtattcctg
      481 aagaggaact gcgtaaagcc actaagtctg ctgtttgcaa gatcaacatc gactcagact
      541 ctcgcctggc tatgactgct gctatccgta aggtattcgc agaaaaaccg gctgagttcg
      601 acccgcgtaa atatctggga ccggctcgcg acaatatgga aaaactctac aagcacaaaa
      661 ttatcaacgt gctgggttct gacaacaagt tagctgaata aattccaaat ctagtattta
      721 aaagttttac ttgatttaat ttatatttta agaagccact caagcaattg agtggctttt
      781 ttgtatccct tcccattata ccatatcgtc acccgtcttc actacagcca ccttcagtgt
      841 tttatggaaa ggaatgaacg ctgcgatgac agcaatcacc agtgccagta tcagtacata
      901 gccgatcagg gttttcaggg caagcagcag ggattgctgc tgcaaagtgg agtacaggct
      961 gttggctgcc aattgtccgg cctcgccgaa ttcgtgccct tgcgccaggg cattgctcaa
     1021 tgcctgattg tatttttgtt cggccagcgg attggtcagc gtcatgtttt ccgaaagaat
     1081 gttcatcccc tttgcctgca gatagtaaag catgttgtta aagaatgaag cggacaggac
     1141 cggagccaat actgagcgga atgaaatcag gaagaaggca ttggacaacg tcaggcgcgg
     1201 gtctaaatct tcgacaacaa acacaccgaa cgcaatgaat atgaccatca tccccactcc
     1261 ccggaacagg atggggaggt agagcatttc ataggttcca taaggggtga taccaaagta
     1321 gaggatagcc agatagatga cgtagcagaa catacctcct gaaatgagga agcgaaaccg
     1381 ccatcgttgc catcggaacc accagaagca aatgacggcc cctaccacat atccgggcaa
     1441 tagccacagg ctcagcgaat tggcgtgtat gctgtctacc cggatgatgc tgttcatata
     1501 gttggttacc agtgaactgg tggctgtcag gaacatggcg agtaccatga agccatatcc
     1561 gatgatggat ttatgcagaa agagtggttt caggttgaca aagggtttgc cttgtgtacg
     1621 ctgccgatgg atgaaaagag ctatcaggag cgggatgacg aatacatata ctctgatctt
     1681 cggggatgcg aaccaatcga gtgttttccc gtaggtaaat gtatagagcg ttagcaggaa
     1741 agcggtggcg atgatgaaca tgcttcttcc gtccatctct ttgaacggaa tgtgcatggg
     1801 acgccttgca tagcggaaga aacagatgac gaacagaatg gcgatcagca agaggatggt
     1861 gacaaaatag tacatgtgct gccattggta gtgataggcc agttgagcgg tgatagccat
     1921 cgatagctgg cctccggaga aaacgatggg gtagaagtag gcatagaatt cacttcgtac
     1981 gtttttcgga ctgaagagcg ggcggatcag gatgatgaac tccaacatga cgaaggcttt
     2041 gagaaatccc atacagaaac tgcataccat gatgacgtcc atactaccgg ttttggcgca
     2101 taccaggctg aagaatatct gtagcagcag atcggtaagc agtaaggttt tcggagtggc
     2161 tatggtgcgt attttcggta cgatgggata ggcaacagcc atccctaccg aagctgaata
     2221 gtaagccatg gtaatatctt cgctcaatac tcccagcgtg ttcgatactt cgaccatact
     2281 tcctgtgtag gcaccgttga gcagggtgat gggaaagatg acaataaaca tggtcacgat
     2341 gcccaaccat tgaggcaccc agggacgggt aggcagattg agcttcacca taagcctaag
     2401 ggcggaccgc ttccgtttct accatcatcc ctgcacggag acattccatc tcttcgggtg
     2461 aggcgtcatt gagatcgatg cggaccggaa tgcgttgctg cactttgacg aagttccctg
     2521 ccgaattgtc ggtcggtacc agggagtatt tcgatccggt ggcttcggaa atggcggtta
     2581 cggtcccgtg aaaagtgcgt ccgctgaaag catctacttt gatgcggact ttttgcccga
     2641 tatagatatg ggctatttga gtctctttat aattggctgt cacccacttg tcattgcccc
     2701 gtaccaggta ggaaagagtt tgtccgcctt gtacgaactg tcccggttca agtgtacgtc
     2761 gtcccgtgta tccgtcatag ggtgcggtga caacggtata cgacaggttt agtcgggcca
     2821 tctccaggtc ggcctccttc cggaggatat tggcttcggc gcctgtactg cgtttgctgg
     2881 tttcggaata ctgcgattgg gccgcttctt tttgtcgcaa cagggcgttg tatcttgccc
     2941 gggtcgcttc gaagttcgct ttggccagtt cataatcctg ttggctgacg gcctgctttt
     3001 tcaggagccg ggtatatcgg ttcagttccg cttcttgctg tgaaaggcgt gccagtgttt
     3061 cggctatgtt agcttcttgt acggctacat ttactcctga agtccggatg ccggagttta
     3121 acacttcctt tgatcccaag gcatccatca aggccgcttc cgcgtctttc agccggatcc
     3181 ggtattcccg gtcgtccagt atcagtaacg tgtcgccggc atgaacatac tggtgttcgg
     3241 taaaacgtac ttctttgata tagcccggta tccggatgtt tagcggagcg atgtattgat
     3301 ccactacggc atcattggtt atctcgtagc gggcgtattt ccagaagtag tttactgtcc
     3361 atgaaatacc tgccaatgcc agcaggatgc atactgtgtt gagaaagatg ttcctgaact
     3421 tcagtcttct caattgtttt agctttatct gatgggtgga catggcggat ttcttttaga
     3481 tctcattgag cacttcatgc agtctcttca ggtcttcgat gcattccgtt atccggcttg
     3541 cctccatctc tgttccggtt tgggcataga tatcgttgat caggggtttc acggtgaggg
     3601 caagttcttc gccttggggc gtcaggaaaa tcaggcggtt tcggcggtcg gaggggcctt
     3661 ctttccttat cacccagttt ttcttttcca gattattaat cagattggtc aggcaagcct
     3721 tgtcctttgc tgttttctca gccagggatt gctggctgat gccttgtttg ttccacaggc
     3781 agttcattac ttgcagcatc tcgaaggtca tatccacgtt gtgacgtttg agtacccgct
     3841 gaacggcctg gcggaatgcc atccaggttc gtaaggtttg taggacgagc tcgcgctccg
     3901 attcgttgtt tgtcatcgtc gtattctttt agtcgctgca aaggtaggaa tattcttcga
     3961 taatagtcaa atgtttgact attattattc gcattaggct acacaaaggg cacagaggat
     4021 gtcgggtgaa atcctttgtg ccctttgctt atgcggttat aaccggtgtg agattaaagc
     4081 tctataacca tcgattggcg gggtgccatt gtcagttctt cattgagtgc cgttactttt
     4141 ccgctaatga cgtcttttcc ttgagtcttg tctttcagca cttcggcata gtatttcagg
     4201 ggaagtttca cttctttatc cgtaccgttc aacaggacga ataccgtttt ccctttatat
     4261 tggcgtgcat aagcatatac gccgtgctgt accatgaact gtttcatgct gcctttggcg
     4321 atcacatcgt tgcccttacg ccagttcagc aggttgcggt agaagttata gctttcattc
     4381 tgcaatcggg tacgtccctc gggagtcagg gcattctctt tatcgtccgc ccatccgccc
     4441 gggaagtcct ttcgtacata gccgtcgctt ttactcttta ctccgttcat catcacctcc
     4501 gttccataat agagttgcgg gatgcgtcgg gtggtcaata aaagggtgga ggcctgtttc
     4561 agcatatcga ggttttcgcc ttcacccaag aaacggtcgg tgtcatgatt ttcgatgaaa
     4621 gccagtacgg aagccggatt gggatacaga taatcgtata caaaattgtt gtagacacgg
     4681 tccaatcctt tgaaccaagt gtccgtttgt tcattcttgg ccgtgttgac tttgtcgaag
     4741 aagctgaaat ccatgactgt tttcaagtga ctgttgcgcg gggcggagag tttggagtct
     4801 ttctgccacc aggctgtata ggccggttcg gtaacccagg tttcgcccac cgtgttgtag
     4861 ttggggtatt cttcgttcag ttctttcatc cagttgctca tggcatcgta atcggcatac
     4921 gggtaggtgt ccatccggat gccgtcgata tcggcgtact caatccacca caggctgttc
     4981 tgcaagaggt atttgtatac gtgagggttc ttttggttga ggtcaggcat ggcttccacg
     5041 aaccagccgt tgttcatctg gtcgaaatcg tactccgagg catacggatc tacatgtgga
     5101 gtcagcttgt aggaagtttg tacaaagttg ttcttgaagt ccgcatggtt gaaccagtcc
     5161 tttgaaggca tgtccttgat ccagggatgt tctactccgc aatgattgaa gatcatgtcc
     5221 atcacgacct taatgccccg gttgtgggct ttcgctatca gtgagcgata ttcctcgtta
     5281 gtgccgaaac gtgggtctac cttgtaataa tcggttgttg catatccgtg atatgagccg
     5341 cctttcatat tattttcgag taccggggtg aaccagagtg cggtcactcc caagtcggta
     5401 aaatagtcca gattttgttc gataccggcc aggtcgcctc cgtgacgtgc gttcgggtcg
     5461 ttgcggtcca ctttatattc ggccatgcct tctatccggt cgttatccgg attgccattg
     5521 gcaaaacggt ccggcatcag caggtataat gcatccgatg cgtcaaaacc tttgtgatcg
     5581 actccggctt tgctgcgtgc tttcaattcg tactctttca ccaatttctt ctttccgacc
     5641 gtaaatgtga tgggcatctt gcccggcttt acttctttat cgagatgcag gtagacaagc
     5701 aggtaattgt tgctttccag tttcacgacg ctgctgagcg atacaccggg ataatttact
     5761 gatacggatg cctggccgat gccttcaccg tataccatta actggagttc cggattgttc
     5821 ataccggtga accagaaggg cggatcgatt ttggatatgt tcatggctgc ataagtggtt
     5881 aatgacagta ggaatgaacc taagagtaac aataattttt tcatgatatt agctcgttat
     5941 tatttaatgt tgctaatata gggtaaatca tcggattgtt ttccgttttc tttcttactg
     6001 tgtgccatct atttatgcaa acgttttcat tggagaattc tccgggatgg agctcaaccg
     6061 atgaggaaca cttttcgatg caatcaggtg aacgtgatgt ccggaaaagg agatgccgtc
     6121 atagcttcgg ctacgcagca ccgtaacttc ggctacgcag caccgtaact tcggctacgc
     6181 agcaccgtaa ctttggctac gcagcaccgt aactttggct acgcagcacc gtaactttag
     6241 ctacacagca ccgtaatttc ggctgcgtgc cgatgtgact tcggttacgt gccactgtgc
     6301 cttctaccgc acatcttcaa atttattttc cattattctc cctctgtgaa actctgtctg
     6361 cactcagtgg tgaattgtcc gaaacgatgc atctatccga tcaattcact tttctccctt
     6421 taagaatttc tcttttcgga tgctttccaa tttattggtg gcacttttgt agtaatctat
     6481 gtagggtgcg ggttcttctt cgtcattatc cggctgctgt agtactgcat tttgtttgga
     6541 ttttgttcgc agaaaagcct gcaagtaatg ctctgtggct ttagtatctc ctattttgtc
     6601 cgataagaac gccaagttat aaagtaaaat atgcttgtca ggggcatatt tgtattgttc
     6661 tttggtagcc ttgatttggt cccgggtttg cttggtttgc ctgtagcagt ctgccaagcc
     6721 tgagtataag cgctccatga tactgtcggc ggggatagtc agggcgatag cctggttcag
     6781 atatcctatt ccctcttgtt tccataatgt cttggagcac gaacgtccca aatagtagag
     6841 taggttggcg ccgggtgact ggcatgattt tgctttgagt agccaatcgc gcgctttata
     6901 gtattctttc gtagcgtagt agctgactcc caggtaataa catgtcagca gtgtgctgtc
     6961 tccccgggcg gtcagatcct gataacgttt gatggcggtg ggatattctt tgcgcagaca
     7021 atacgccagt gcgttttgac ggttcacttc tacattggtg ctgtccgtcc ggcggtatgc
     7081 ctctgtcagg gcaattgccc cttcgtaatc tttcattgta ttgaagatac tgcccagctt
     7141 agctaccgag agatagtcgg agggatattt cctgatgatg gaaagatagc aaaacatact
     7201 ttctaccggc atgccggctc cttccatgct ttccgccatc agtcgcaata cggtggcgga
     7261 actgtctttc ctggccaatg cgatactctc acgcaatgca tcgccgtatc gctgatagtt
     7321 gtataacaag cgggtgtatt gcaagtgtgc gtaaatatgt tcgggattga gttccatcac
     7381 cttccgataa taccccaagg cctcgttaaa tttgctcaat tgcctgcaac attctgctgc
     7441 ctctaccaat gcctgctgat tttcgggcag ctcgataatg atatgttgca aagtggacag
     7501 ggcttcggcg gtacgcccta aaccttttaa agctttggct ttctgtatga gtaactgtgg
     7561 tgatgcactt tcttcatcaa tcagtctgat caccgtttta tagtcatagt ttgccattgc
     7621 ttcttgaacg gaggcggtgt tctgggctcg cagcattacg ctgaagccca gatagaggag
     7681 gagtatccaa tgtttcatgg gggatagatt ctattgtttc tgactttcta acggtattcc
     7741 ttctttgaag aacttttctt tctgtaagtc tttcagccaa ttttcggcag cgttgtaata
     7801 attttcaagt ccgagtacaa gttccccttt ctcactcacc ggttcttctt tcctggcatt
     7861 cgcctttcgg gtttttaaga aagcctgcag ataacgttcg gccgatttgt tgtctttgag
     7921 ttgatatgaa tagttccagg cgatgtcata aagaagttta tggttcgtct tgtcatattt
     7981 gtacagttct ttgagagcct ggatttgctt tggagtatcc tgagccagtt tacaacaatc
     8041 caccaagcct ttgtaaagtc ggatcatagt gctgtctttg ggaatggtca gttcgatagc
     8101 tttctccagg tgttcgatgc cttctttttt ccaggaagtc ttggcgcagc aacgtcccag
     8161 ataatagagc agattgggat tttcttccat ctctttttgc agtttgctga aacacgcgtg
     8221 cgcttcgtaa taatattcat ccgcgtaata gctgactccc aggtagtata aggtctgcgt
     8281 actgctgtcc ccctgttggc acagcttttc atagcgtttg atggctgtcg gatattgttc
     8341 ggcgtggcag taggcgagag cgttttgctg gttgacaatc aggttggtgg agtcccgttc
     8401 cctatagcgt tcggtagctt ggatggcata ttcgggatat ccagccacaa tgttcaggtt
     8461 tccgagtttg gccgcagcca gataatcgtc cggatattta tcctgaatga cttcatagca
     8521 accgatagcc ggtagtatct gttgcatccc ttcaaggctt tgagcctgta ggtggagcac
     8581 tacggccgaa ctgtccgttt cggacatcat tgaactttct ccaaaagcct cagcatagtt
     8641 tttggtgttg caaagcaggt tgatgaattg caaacgggca tacttgtttt tgggattcag
     8701 gctgatggct ttccggtagt agtccagcgc atcgttgtac ttggccattg ctttacagca
     8761 ttccgctgct tcgatgtgtg cctgttggtt ggtggagtct tccgctatca cttggcggat
     8821 ggaacgtaga gcttccgcat tgctgccgat tcctttcagg gcttttgctt tctgcattaa
     8881 cagtgggatg gtgggaggtt ccttgtttat cagttcaacg gcagtctcgt agtcatagtt
     8941 tgccattgct tcctgaattt tgttttgatt ctggcccatc agtaggggac tgaggcaaag
     9001 acagaaaata aggaagagtg gtttcattgt tcttgttctc ataggacgta ttgttttatt
     9061 gtccgcaagt tagtaaaaat atccattcta cgaaagattc gtaatatctt ttagatagat
     9121 taacgcaaaa aaaagacgcc cttctttgcg aaaagaagga cgtctacctt actaatgaaa
     9181 aaaatatcgt ttacatgagg aatccgagca ggataccggc agctacagcc gaaccgataa
     9241 cccccgctac gttaggaccc atggcgtgca tcagcagata gttggtcgga tcatattcca
     9301 aaccgattac ctgtgaaata cgtgccgagt cgggtacggc ggatacacct gcattaccga
     9361 tcagcggatt gatcttattg cctttcttca agaatagatt gaagaatttg acaaacatga
     9421 cacctgacgc tgttgcgatg atgaaagaga atgcaccgag gataaagatc aagatagaat
     9481 cccaggtgag gaattgtgaa gcttgggtag aagctcccac agtcagtccc aacaggatag
     9541 tgatcacatc gatcaacgga ccactggccg tatttgccaa acgacgggtt actccacttt
     9601 ctttcagaag gttaccgaag aacagcatac ccagcaaagg cagacccgaa ggaaccagga
     9661 agcatgtaag caacagaccc acgatgggga agattacttt ttccgtatgc gatacgattc
     9721 tcggtggttt catgcggatc agacgctcgt gtttggtggt tagcgcacgc atgataggtg
     9781 gctgtatcac cggcaccagt gccatgtaag aataggctga cacagcgatg gcacccatca
     9841 ggttgggagc cagtttggac gaaaggaaga tggccgtcgg tccgtcggca ccgccaatga
     9901 taccgatagc acccgcctgg ttgggttcga acccaatgag cagggcaatg atatacgcac
     9961 cgaagatacc gaattgggcg gcagctccga tcagcatcaa tttggggttg gagatcagcg
    10021 ccgagaagtc cgtcatggct ccgataccca ggaaaatgag cggcggatac cagccggagg
    10081 ttactccttg ataaaggatg ttcagtaccg aaccttcttc gtaaataccc acttttaatc
    10141 cggcttccat attgaatgga atattaccga tcagaatacc gaagccaatg gggatcagca
    10201 gcatcggttc aaattctttg gctacggcaa ggtagataaa gaagagaccg attagcaaca
    10261 tgaaaagatg tccgggtgtc gcgttcgcaa aaccggtgta tccccagaag tcaacaaggt
    10321 tattccctaa gaatgatacg aaatctccca taattattca atgattacga ggtctgtacc
    10381 ttcaagtaca gaatctcctt tattaacttt aatttctgct acttttccgt ctttattggc
    10441 attgatgttg ttttccatct tcatagcctc aaggatgatg atcgtctggc ctctcttcac
    10501 ggtatcccct tctttcactt ttatgtcgag aataacgccc ggaagcggag atttcacacc
    10561 gtcttttttg gaagctgtcg gttgtttggt tactaccgga gcacctgttt ccgttttcgg
    10621 agcggctgcc ggacgggtca ccggtttcgg agcggctttg acgggcttgt ccaactctac
    10681 tttataagag gttccgttca cttcaacgtt ggctatgtta tcttctacat cgttcactgt
    10741 aacgttgtaa aggttgccgt tgattttata tttatattgt ttcattgctt cattttatta
    10801 gggttagtaa ttatcttttc ggagtctgac gcagtgtgta gatcttcgaa ctccaggggg
    10861 agtaggtgcg tttcactttg ttgatagtca aaatcatgtc ttcaacgtcg tgagcgtcat
    10921 tcaggtattc atgcaaagcc atggcgatcg cggcggtttc ttcacctgtg tggctaccca
    10981 ggttcttttc cttcgcttcc gtcttgtcgg tgataccggt ggctttcatc gcgtttttct
    11041 tacccagtct gacagctacg ttacctaccg ccttgaatga aagatacaag agtaccaaac
    11101 ctatgaatac gaccgacatg gcgatgatgg ccataccgat accgatagag tcgtgtttct
    11161 tgaagttctc gatcttcggg tttttgtcga tagtcatatt gttggtgctc ggagtgacat
    11221 agctgtgttc tccttcacct tttactaccc agttggcact tccgtctttt tcgcgagcgt
    11281 atgaacggtc ggcaagctga ccggcgggga tggttacttc gtcaatcaga gttttaccgt
    11341 tagagtcata caaagcaatg taattctctt tgttcgggtc gagcgtaaag ttcacgtgga
    11401 acgtaccccg gttaggcatt ccgtctgccc agaacaaagc atgttggcgc ggcttgatca
    11461 gagtcagcac gtcgcctttg ggaataggat atttggtcgg attgttttta tcgttcgtca
    11521 gaaagcaacc ttccagattt acagaagcga aagaggtgtt gaatatctct atccacgcat
    11581 tgtgcagtcc gtagtcatcc tgatagttct ggtcgttgac gaccaaaacc tcattgattc
    11641 tcagactggt ggcactttgc gccctgagcc ccatgcaaac cattgccagc agagcgataa
    11701 atatcccgat tcttttctta ttcataacaa tcgatgttta atttgttaca atggaatatt
    11761 accgtgcttt ttagcagggt tggttaattt tttggtctgc agctgttgca gggcgcggat
    11821 cacgcggaaa cgagtgtttc tcggttcgat aacgtcgtcg atgtaaccgt atttggctgc
    11881 attgtacggg ttggcgaaca gtttagtgta ctcggcttcc ttgtctgcca ggaattgagc
    11941 agggttttcc tgatctttgg cttctttggc atacaatacc gctactgcac cggcacctcc
    12001 cattacggcg atttcggctg tcggccatgc atagttcatg tcgccgcgga gttgcttgca
    12061 actcattacg atgtgcgaac caccgtaaga tttacgcagg gtaacagtta ccttgggcac
    12121 agtggcttca ccataagcgt acagcaactt ggctccgtgc aggattacac cattatattc
    12181 ctgacccgta cccggaagga atcctggaac gtctaccaat gtcaccagtg gaatgttgaa
    12241 tgcgtcgcag aagcgaacga agcgtgcacc tttgcgtgaa gcattgctgt cgagtactcc
    12301 ggcgaggtat ttaggctgat tggcaaccac acctaccgac tgtccgttca tacgggcaaa
    12361 accgataata agatttttcg catagtcttt ctgtacttcc aggaattctc cgttatcgat
    12421 gatggcgccg atcacttcgt acatatcgta cggtttgttc gggctgtcgg ggatgatctc
    12481 gttcagcagg tcgtccatac ggtcgatggg gtcggtacag ttcaccaatg gagcttcttc
    12541 caggttgttt tgcggaataa agctgagaag cttgcgaata atcgccagac cttcttcact
    12601 ggtttcggca gtgaagtgag ttacaccgga cttgctggca tgtacgcttg caccacccag
    12661 atcttcctga gacacgtctt caccagttac tgttttcaca acagccggtc cggtgaggaa
    12721 catgtaagat gtaccttccg tcatcagcgt gaagtctgtc agggcgggag agtaaaccgc
    12781 accgccggca cacggaccga aaatacctga aatctgtggg atgacacccg aagccatgat
    12841 gttgcgctgg aagatttcag cataaccgga cagggcgttg atgccttcct gaatacgtgc
    12901 gccacccgag tcgttgatac cgataacagg ggcacccatc ttcatggcca tatccattac
    12961 tttacagatc ttttgtgcca tggtttccga cagtgaacca ccgaatactg tgaaatcttg
    13021 tgcgaaaaca tatactaatc taccttctat cgttccataa ccggttacca caccgtcgcc
    13081 gaggaaatgt tttttctctt gtccgaaatt ggtacatctg tgttgaacaa acatatccag
    13141 ttcttcgaaa ctaccttcgt caagcaactg tgcaatacgc tcgcgggctg tatatttgcc
    13201 tttggcgtgt tgtttttcaa tagccttttc gccaccacct aaacgagcct gagcacgaag
    13261 ttcaataagc tcttttactt tttcaagctg gttactcatg agtttttctt aatttaaagg
    13321 gttataatat ttacaaccgg acgattgaca acccggatgg ggaatttaat gtaaagaaaa
    13381 attccgtttg tccgtggcgc ggatcgtccg aatcgtacat ctttttagtg ttcgcagagt
    13441 tctgtcagta cgcccagagt tgatttcggg tgaaggaaag caatgttcag gccttcggca
    13501 cctttgcgcg gagctttgtc gatcaggcgg atctctttgc tttcggcttc ggccagggca
    13561 ttggctacgc cgtcttcaat ggcgaatgct acgtgatgaa cacctgcacc tttgttttcg
    13621 atgaatttcg cgatggtact ttccggacat gtgggttcca gtaattcgat tttggtatca
    13681 cctactttca gaaaggctgt tcttactttt tgatcttcta cagtttcgat gttgtagcat
    13741 ttcaaaccta aaacgttttc ataatacgga agggcttctt cgatactttt tacggcaatg
    13801 cccaaatg
//
