LOCUS       c00407_gnlPro..         3759 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMBNEDIB_407.
ACCESSION   c00407_gnlPro..
VERSION     c00407_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:07:03
            Original ID  :: gnl|Prokka|BMBNEDIB_407
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3759
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3759
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[955:3757]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      956..3757
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3759
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3759
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             334..567
                     /locus_tag="ctg407_1"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTARTRKAKTEPAKSKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFYPIEEVHQRIRSWMDNYQGKK"
     CDS             537..878
                     /locus_tag="ctg407_2"
                     /transl_table=11
                     /translation="MDGQLSRKKVIGSPIYEESLERIFVEGIERFGIFQARKYLEHILN
                     TVEKLENDYPYYPECRHLATKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KQARNIHIE"
     CDS             complement(956..1999)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg407_3"
                     /sec_met_domain="IlvN (E-value: 7.5e-48, bitscore: 150.9,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.3e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(2066..2791)
                     /locus_tag="ctg407_4"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(2798..3352)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg407_5"
                     /sec_met_domain="ALS_ss_C (E-value: 7.3e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLQEKQQ"
     CDS             complement(3368..3757)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg407_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-33, bitscore:
                     104.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="RTVCFFTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQW
                     QELFFHERYSNTIMENPDFVAIAKAYGIASRAVEKREELDDAIAEMLNHDGAYVLVANV
                     ETCGMVYPMVPAGGSVTNMIMGDEK"
ORIGIN
        1 acacatcatc atatgatttt catatactct tttaatgtat aagacgtagt aaatataaga
       61 aataaaaaaa tatgtaataa agacctacac accccaccct cccaaattca tgcttattgt
      121 gcgtatatag cggataagcg attaaaaata gcggttatgt gacataaata aattcgaata
      181 ccattttgag gggatggaga cggggcacgc cccgtctcta caactgggta atgagttaat
      241 cctatagacc tacttttttc cttatcaaat atcttattac atggaaatta ttccatacat
      301 ttgccactgt actaataaat aacagttacg actatgacaa aattaagcaa catccccgcc
      361 aaggaaacca cggccaagac cgcaagaaca cgtaaggcca agaccgaacc cgcaaagtcc
      421 aagtgggatc ccaccaagcc ggtacaattc acacaagagg agatatggga acatatccat
      481 gagatcgaga aggggccgtt ctatcctatt gaagaagtac atcaaagaat aagatcatgg
      541 atggacaact atcaaggaaa aaagtaatcg gttctcccat ttacgaggaa agccttgaga
      601 ggattttcgt ggaaggtata gaacgattcg gcatattcca agcccggaaa tatcttgagc
      661 acatattgaa tacagtcgag aaactggaaa acgactatcc ttattatccc gaatgccgac
      721 acctagctac gaaaagccgc atgtaccgga acatcatcct ggattcacac cttatcatct
      781 accgcatcac cgaggagcgt atcgaagtgc tagacatcgt ccattccgca tccagcatgc
      841 gaaagatcaa acaggctagg aatatccaca tcgaatgatg cagagaaaca gaaaaaggcg
      901 agccacccgt aagtgacccg cctctttttg ctgatatata aggattaaga ttggattagt
      961 tgttctccgg acgaagcttg cgtacggtaa cagctgtctg ccacatctcg ctctcgcgca
     1021 atgccttcaa ttcagcctcc aatttctcac gataatccgg cttagagttt gagtcgatag
     1081 agatctgagc ctcgttaccg cattttacgt tcgcgtacaa tttctcgaca accggcttga
     1141 tagcgtcgtg gaacggaccc atccagtcca aagcgccacg ctgggcagtc gtagagcagt
     1201 tcgcgtacat ccagtccata ccgttcttag cgaataaagg catcaaggat tgagtcaact
     1261 cctcgaccgt ctcgttgaaa gcctcggaag gagtgtgccc attctcgcgc aatacctcat
     1321 actgggccaa caacagacct tggatagcgc ccatcaagga accgcgctca ccggtcaagt
     1381 cggaagtagc ctcacggatg aaagtcgtct cgaacaaata accggaaccg ataccgatac
     1441 ccaacgccaa cgtacgatcc attgccttgc cggtagcgtc ttgatagata gcgaaagaag
     1501 agttcaagcc acgcccctca aggaacatgg aacgcaaaga cgtaccagac cccttcggag
     1561 cgaccatgat cacgtcaata tccgcaggag gaacaacacc tgtacgatcg ttccaagtga
     1621 tcgcgaagcc atgagagaaa tacagggcct tgccagctgt caaataaggc ttcatcgtag
     1681 gccatacaga cattacggca gcgtcggaca ataagcacat gatgatcgtg gccttgtcgc
     1741 aagcctcctc gataccgaac agagtctcac ccggaaccca tccgtcctca accgctttct
     1801 cgtaagtctt accttggcgc tgaccaacga ttacgttgaa gccattgtca cgaaggttca
     1861 atgactgtcc cggtccctgt acgccatagc cgataacagc gattgtctca tcttttaata
     1921 tctctcttgc cttttccaac ggaaattcct cgcgggtcat tacattctct acaacaccgc
     1981 caaaattcat ttgtgccatt ttctttttaa ctattaannn nnnnnnncta ttaatgttta
     2041 aaaacctatt tatgtatctc ttttattatc tccaagtaac cgccgcacga cagatcgcct
     2101 ttccctcatg gcaaatagcc atgtcttgct tatcgggagc ggactccgcc ttatgaagcg
     2161 taagcggcat accttgttta ccctcggatt ggtaggcgat ctccagacgg ccgatctcac
     2221 gggtcttgaa ctggtcgata tcgaacaaat ccagcaggtg ctcgatatac ttcacgctat
     2281 tgaagtgacc gttgatatcc aagtcgctgt atttgatcga atacgggatt ccctccgcct
     2341 tattctccgc cggcatgatc ttgcccggct tctcgatcgg gcacggacgc tcgtcgatat
     2401 atttgcccaa tgcctctata tccaataagg taggacggcg ggtctccacg tcgatagccg
     2461 cccaaataga acgggcgaat ccaaaggttt tcccattctc atccgccagc tcaaaacaac
     2521 ggctggtgaa aaggcgtccg acctcatcga tccaagtgta taaattaatc ttatcgaagg
     2581 cggtaggata ttccttcatc tcgatagcca gacgggacaa cacccaagcc gtatgacgct
     2641 ccgacatatc attgaaaccg aacccacgct ctccggcatg gctggaagcg gcgtgaatca
     2701 aatagttacc aatcataggg agcgttacac gtcccctaaa atccatcaaa tatggctccg
     2761 ccacgaaatg aaataatcct actttctcca tatcttatta ttgttgcttt tcctgtaact
     2821 ttcgctccat atcggccaac atatcgctca agcgctccac cttgctcttc gtgatagcca
     2881 cacgtccgga gcggatgaat tgcaggacac cgatcgtctc gctcaactca ttgaacaagg
     2941 cctgtgtctc gtcatagtgg ccactcttct ccaataccac gcaggtctcg ttcatctcca
     3001 agatacgggc gttgtattta cggatcaatc cctccacggt tcccatcttg atgaaaagct
     3061 cggtacttag cttataaaga gcgatctctt gataaaccag atcctcatcc gtattataat
     3121 aagccttcaa aatatccaca cgtttatcga tctgtttcac caccttatcg atcatatcct
     3181 catcggcgaa tgtcgtgatc gtaaacttat ggatgccctt gatagcggac ggagagacgg
     3241 acagagtctc gatgttcagc tgtcggcgtg taaagataat cgttatctgg ttcaaaagac
     3301 ctacgatatt ctctgaaaag ataataacgg tatataattt ctttgttgtc atagcttcat
     3361 ctcctcctta tttctcgtct cccataatca tgtttgtcac gcttcccccg gcaggaacca
     3421 tcggatacac cattccgcaa gtctccacgt tagcgaccaa cacgtaagcg ccgtcgtggt
     3481 ttagcatctc ggcgatagcg tcgtccaatt cctcccgctt ttcaacggca cggctggcga
     3541 taccataggc tttagcgatc gccacgaaat ccggattctc catgatggtg tttgaataac
     3601 gctcgtggaa gaacaattct tgccactgac gtaccatacc taagaagtta ttattaagaa
     3661 taataatctt cacgttcagt ttctcctgca tgatggtacc caattcctga atcgtcatct
     3721 gcataccccc atcaccggta aagaagcaga ccgtacggt
//
