LOCUS       c00068_gnlPro..        10342 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEJEJGKB_68.
ACCESSION   c00068_gnlPro..
VERSION     c00068_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:52:21
            Original ID  :: gnl|Prokka|JEJEJGKB_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10342
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10342
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2580:7109]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2581..7109
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10342
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10342
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             41..2452
                     /locus_tag="ctg68_1"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISIIYSCLGYNKAERIIPSAQADMRLNVQMNYTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPNDDASA
                     AMSVGRYHEHARNRLNSTVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVAGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             2581..2991
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 2.7e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             3028..4581
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_3"
                     /sec_met_domain="CT_Btheta (E-value: 1e-292, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             4603..5490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_4"
                     /sec_met_domain="OAD_gamma (E-value: 9.6e-13, bitscore:
                     38.4, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADGQP
                     GRGTFHVNFVLDPSKENYVALYDADGKTLIDEITIPAGQLADISYGRVIDGEKDWAQLK
                     KVTPSTNNLTLDSNEKIDNFRVNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGKLSIAA
                     SKRNVEKAVGSASVTADAGQESGEIFAAIATALYEMSDDNHDIENTVLTIRKVQRAYSP
                     WSSKLYGLRQTPQK"
     CDS             5513..5944
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.8; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.1e-21, bitscore:
                     64.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIAELEVNGTPYQVKMEKPAKKQ
                     MVTLKRPAQAPTTASGDPVVSRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLII
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             5949..7109
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_6"
                     /sec_met_domain="OAD_beta (E-value: 9.2e-154, bitscore:
                     501.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(7176..7322)
                     /locus_tag="ctg68_7"
                     /transl_table=11
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEISPVPIE
                     QAN"
     CDS             complement(7391..8107)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_8"
                     /sec_met_domain="Peptidase_M22 (E-value: 8.1e-28, bitscore:
                     87.5, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEVAKSKGMKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCETVITSPNACFIDGIYPLAVNMASLSQKAYDDARFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
     CDS             8309..9169
                     /locus_tag="ctg68_9"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMEL
                     RSLLLQSLERGKVEFNIFIEYIGKDTPTQINLAAVENYYNQIKEIAEKLNISVPNDWFQ
                     TLLRMPDAIKSETVEPDESEWGVVLETVKDAIKHLCDFRIQEGAMLQKLFEQKIANIAT
                     LLKEVEKYEGERIEKIKARIMDNLQKIAEKDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             9184..9750
                     /locus_tag="ctg68_10"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINYLLKQDLHLRFSISATSRAPRGTE
                     KNGVEYYFLTPEEFRSRIANGDFLEYEEVYTDKYYGTLKSEVERILNEGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPCIDDLRKRLEGRGTDSPEVIESRIAKAEYELGFTGQFD
                     KVVVNDDLETAQKDALKIIREFLNK"
     CDS             9754..9933
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MPNIFKNTRFMMGLSIVCGIASLVLGGISLYYKEYIIGGALIFNI
                     FICFINYKGWQKKG"
     CDS             9945..10340
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_12"
                     /sec_met_domain="CTP_transf_like (E-value: 2e-23, bitscore:
                     72.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLKTGIYSGSFNPIHIGHLALANWLCEFEGLDEVWFVVTPHNPL
                     KKKDDLLDDSLRLEMAQAAIDGYPKFKVCDIEFHLPKPSYSIDTLRALSSNYPDRDFYF
                     IMGADNWLLFPRWKEYEKILQNYKLLIY"
ORIGIN
        1 cttttttctc gttagtattt ttataattga acaatagatt atgaagattc gtgcgatagc
       61 cgcgctgcta tttatactta tttccgtgag tgcctttggc gaaggccgca taaaaatcac
      121 tggttatgtc cgtgacgccg acggtaaccc tctggaatta gtgaatgtcc gggttaagaa
      181 cacgttgatc ggctccatga ccaacgagaa gggatattat tccttttcca tatcgccggg
      241 ggattctatc tccattattt actcttgtct gggatataat aaagctgaac gtatcattcc
      301 ttcagcacaa gccgatatgc gcctgaacgt acagatgaac tatacctcat ttgatttagg
      361 ggaagtatct gttactgcca tccgcaagca gaccacgacc atggagtccc taaatgcgga
      421 caaaatcaag ttattgcccg atccttccgg aggtagtata gagagcttgg tcgttacgtt
      481 tgccggagta tcgtccaata acgagttaag ttcccagtat tccgtacgtg gaggtagtta
      541 tgatgaaaat atcgtttatg tgaatgggat cgaggtattc cgtccacttc tgattcgctc
      601 gggacaacaa gagggcctta gctttatcaa tccggaccta acggaggcgg tcaatttcgc
      661 cgccggtggc ttcgaggctc gttacggaga caagatgagt tctgtgctgg atattaccta
      721 taaaaaacct aagatattcg aaggctcggc ttctgcgagc ttgttgggcg cgaatgctta
      781 tgtaggcagt tctatcggta aatttaccca agtaacgggt ttccgcttta aaagcggtcg
      841 gtctattttg ggtaccatgg atacagacgc agaatacgac cctaaattta tcgatttgca
      901 aacttacatc acgtaccaat tggcccctaa atgggaaatc aatttcttgg gaaacctcgc
      961 taacaataat tataaattca ccccttatag ccgagaaacc tctttcggta cagccgagca
     1021 tcccaagaac ttcaaagtct atttcgacgg aagggaaaga gaccgtttcc aaaccttatt
     1081 cggtgcgctt acattgaaac acaaccccaa tgagaacaca gagttgggac ttcaagcctc
     1141 cgctttcaaa agcaaggaag aagagggata cgatatcgcc ggagaatatt ggctgagcga
     1201 gaacggagcg gaaaatccga atgacgacgc gtcagccgcc atgtccgtag gccgttatca
     1261 cgagcacgca cgaaaccgtt tgaactccac cgtcatgaat gtcgggcact atgggatggc
     1321 ccgcctttta aacaatacgt tgaaatgggg agccacggta caaatggaga aaatcaatga
     1381 taagatcagt gaatgggaaa aaagggattc ctcaggttat tctttgcccc aaaccggtaa
     1441 taacgtaagt gtatattcga acctcttttc tgataatcag atagaaagca cacgcttttc
     1501 cgcttatgcg caagacgcat tcaaattcag gaccaagcaa ggtctgttca cgttagtcgc
     1561 aggggttaga ggtagttatt ggacttataa taaggagttc cttttcagtc cccgtgcctc
     1621 attgggcttt atcccgaact tcgaccaaga cttgacgctc cgtttcgcca ccggactgta
     1681 ttatcaatcg cccttctaca aggaattacg tagagtagac aaagataaga acggcaataa
     1741 tatcacggta ttgaacaaag atctaaagtc acaacgctcc atccatttca tattgggagg
     1801 agattatacg ttccgtgccg tagaccggaa tttcaaggtg accgccgaga tgtactataa
     1861 aaagctggac aatctgaatc cctacaccgt agataacgtc aagatccgct attacggtga
     1921 gaactgcgcc aaaggttacg ccatgggact cgatgtcaaa ttcttcggag aattcgtacc
     1981 gggtaccgac tcatggatca gcttctcctt gatgaaagcc cagcaaacca tccgggaaac
     2041 aacgaccgtt cctatggcca atagccaagg ctacaacatc tcactcttct tccaagatta
     2101 tttcccgggc tataaacgag tcaagctaaa tctgaaagga gttctatccg gaggacttcc
     2161 ccagacaatc ccgggcaaag gatacgaagc cggctatttc cgtacgcccg cctacaaacg
     2221 tgtagatatc ggcctctcct atcaattggc aggaggcacg gacgctatca tggacagggg
     2281 cttcttccgc catttgaaaa acatttggct aggtctggat gtgtttaaca tattagacat
     2341 caaaaacgtt agttcctact attggataac agatgtatat aatgtccaat acgcagttcc
     2401 aaactatctg accggacgtc aattgaacgt tcgtctgatt gtcgattttt aataaaatgt
     2461 atctttaaac acatttactg ggagataaaa acaaaaaatt atttcctcat tcataaaaag
     2521 tagtgtacat ttgcacacaa tagaaacaaa catttactaa atctttaaat tattattgac
     2581 atggaactta cacatatcga acatttaggt atcgcagtga agagtatcga ggcttgttta
     2641 ccctattatg aaggcgttct tggattaaaa tgctacaata tcgaagtagt agcagaccaa
     2701 aaagtaaaaa ccgcattttt caaggtagga cagactaaga ttgaactact agagccgacc
     2761 agcgaagata gcacgatcgc gaaatttatc gagaaaaaag gtgaaggtat ccaccatatc
     2821 gcattcgcgg tacctgatgt acaggcagct ttgaacgagg ctgaggaaaa aggcgttaaa
     2881 ttaatcgata aagctcctcg tggtggcgcg gaaggcttga acatcgcttt ccttcacccg
     2941 aaatcaactt gcagcgtatt gacagaactt tgcatgccgg gcaacaaata attaatccgt
     3001 tcatttctaa caacaaatca aaatacaatg agtaaccagc ttgaaaaagt aaaagagctc
     3061 atcgcacttc gtgagcaagc tcgcttgggt ggaggagaga aaagaatcga atcacagcac
     3121 aaaaaaggca aatataccgc tcgtgagcgt atcgccatgt tgcttgacga aggtagtttc
     3181 gaggaattcg acatgtttgt tcaacaccgt tgtacaaact tcggtatcga gaaaactaaa
     3241 tatttaggcg atggtatcgt aacaggttat ggtacgatcg acggacgttt ggtatatatc
     3301 ttcgctcaag atttcaccgt attcggtgga gccttgtctg aggctttggc tatgaagatc
     3361 tgtaaagtaa tggatcaagc catgaagatg ggcgctcccg ttatcggttt gaacgactcc
     3421 ggcggagctc gtatccaaga aggtgtaaac gccttggcag gatatgcgga gattttccaa
     3481 cgtaacatct tggcatctgg tgttgttccc cagatttccg gtatcttcgg cccttgcgcc
     3541 ggtggagccg tttattctcc ggctttgaca gacttcaaca tcatgacacg tggtaccagc
     3601 tacatgttct tgacaggtcc gaaagtagta aaaaccgtaa caggtgagga tgtaacccaa
     3661 gagcagttgg gtggagccag cgtacacact acaaaatcag gtgtagccca tttcgctgtt
     3721 gatacagaag aggatggttt gcaattgatt cgtaaattgc tcagtttctt acctcagaac
     3781 aacttagagg aaacgccgtt agttgagtgt aaagacccga tcgatcgtct ggatgatgta
     3841 ttgaacgata tcattcccga taacgctaac caatcttacg atatgtatga ggttatcggt
     3901 acgatcgtcg ataacaacga gttcctagag gtccatgcgg actacgctaa gaatatcatc
     3961 gtaggtttcg ctcgtttcaa cggacaatct gtcggtatcg tagccaacca gccgaaggtt
     4021 atggcaggat gcttggatag caacgcatct cgtaaagcag gtcgcttcgt tcgtttctgc
     4081 gacgctttca atattccttt ggtaacattg gttgacgttc cgggattcct tccgggtaca
     4141 ggtcaggaat acaacggtgt aatccttcat ggcgctaaat tgctttacgc ttatggtgag
     4201 gctaccgttc ctaagattac cgttacattg cgtaagtctt acggtggagc ttattgcgtg
     4261 atgagttcta aacatttacg tggtgatatg aattacgcat ggccgacagc cgagatcgcc
     4321 gttatgggcc cgagcggtgc cgtagaggtt atcttcgcca aggaagtagc agccgctgaa
     4381 gatccgaaag catgcgcagc agagaaagaa gctgaatata agaaagcatt cgctaatcct
     4441 tataacgcag ctcaatacgg ttatatcgac gatgttatcg aaccgcgtaa cactcgtttc
     4501 cgtataattc gtgctttgca gcaattgcag actaagaagc taagcaatcc tgctaagaaa
     4561 catgataacc tgcctctata atccgtaaaa caggagatga atatgataaa taagaaaata
     4621 ggggtattgc tattgttcgc tttgctcatt tcattcgggg caaaggcaca gcgcgcaacc
     4681 tccatgcgaa ttaatgaagt attggttatc aacgaggata acttcgttga tgactatggc
     4741 aaacgtcatg gctggattga gttgttcaac acttcggccg gaacggtaaa tatcgcggga
     4801 tgctatttga cagacgacaa aaacaatccc atgaaatatc cgatcccgaa gggagacgta
     4861 ttaactcaga tccaaccccg ccagcacaca ctattttggg ctgacggaca gccgggcaga
     4921 ggtacattcc acgttaactt cgtattagat ccctctaagg agaattatgt tgccttatat
     4981 gacgccgacg gtaagacctt gatcgatgag atcacaattc cggcaggcca attagcagac
     5041 attagctacg gtagagtgat tgatggcgaa aaagactggg cacagttaaa gaaagtcact
     5101 cccagtacga acaacttgac gttggactcc aatgagaaaa tcgataactt cagggttaat
     5161 gactctttag gtatcggtat gactatcacg gctatggctg ttgtattctt aggtctgttc
     5221 ttgttgtaca tcatctttaa gcagattggt aaattatcta tcgccgctag caaacgtaac
     5281 gtagagaagg ccgtaggttc tgcttcagtt accgcagacg caggacaaga atctggagag
     5341 atattcgccg ccatcgctac cgctctatac gaaatgagcg atgataatca cgatatcgag
     5401 aacacggttc tcactatacg taaggtacaa cgagcttatt ctccttggag ttcaaaactc
     5461 tatggcttac gtcaaactcc tcaaaagtaa ttatctaaaa acgaactaaa gaatgaaaag
     5521 ttttaaatat accattaacg gtaacgtata taaagtacac atcaattctg tagtggatga
     5581 tatcgcagaa cttgaagtaa acggaactcc ctaccaagtt aagatggaga aaccggcaaa
     5641 gaaacaaatg gttacattga aacgcccagc tcaagccccg actacggcaa gtggagaccc
     5701 tgttgtttcc cgtccggcgg cttctacgac acaaggggct gttaagactc cgctaccagg
     5761 tgttatcttg caggttaagt gcaacgtagg tgataccgtg aagagaggtc aaaccttgat
     5821 tatccttgag gctatgaaga tggagaacaa catcaacgca gaccgtgacg gtaagattat
     5881 agaaattaaa gtacacaagg gagactctgt gctagaaggt gctgatctcg tagtaatcgg
     5941 ataagactat gcaagagagc tttttaacat tcttaggtga gaacttacaa ctgttcctta
     6001 cctatacagg tgtatacaac gctactccgg gacatctcat catgattctg gtaggtctgt
     6061 tgtttatatt cctggcgatt aaatatgagt ttgaaccgat gcttttgatc cctatcggat
     6121 tcggtatctt gatcggtaat atccctttca aggacgcagg tcttcaagta ggtatttatg
     6181 agcaagggtc tgtactgaac atcctctatc agggtgtgac ctctggatgg tatccgccat
     6241 tgatcttcct cggcatcggg gccatgaccg acttctccgc attgatctcc aatccaaagt
     6301 tgatgttgat cggtgcagcg gctcagttcg gtatctttgg tgcttatacg attgctcttc
     6361 aaatgggatt tgagccgaac caagcaggtg ctatcggtat tatcggtggt gctgacggtc
     6421 cgacggctat cttcctttct tctaagttag cgccaaactt aatgggtgcg atcgcggtat
     6481 ccgcctactc atacatggcg ttggttccta ttatccaacc accgttcatg agattgctta
     6541 cgactaagaa agagcgtttg atccgtatga aaccgccgag agccgtttct tccacggaaa
     6601 aaattatctt cccgatcgtt ggcttgttgc ttacttgctt cttggttccg tccggtttac
     6661 cattgttagg tatgctattc ttcggaaact tattgaaaga aagtggcgtg actcgtcgtt
     6721 tggcagaaac tgctcgtggt cctctgatcg atacaatcac gatcttattg ggtatcacgg
     6781 taggtgcttc tactcaagca actcagttct tgacattgaa ctctatcaag atcttcggtc
     6841 taggtgcgtt atcattcgtg atcgctactt gcgccggtgt attgttcgtt aaattattca
     6901 atttaatatt gaaagacggc aataagatca atccgcttat cggtaacgcc ggtgtatctg
     6961 ctgttcccga ctcagctcgt atctctcaag tcgtaggttt ggaatacgac ccgaccaatt
     7021 acttgttgat gcacgctatg ggtccgaacg tagcaggtgt aatcggttcc gctgtagctg
     7081 ccggtatctt gctaggattc cttggttaat aaaacaacta tctatattaa aaaaggcgag
     7141 gtccgaaagg atcccgcctt tttatgttat tgttctcagt tagcttgctc tataggaacc
     7201 ggactaatct ccgtactcgt atcctccacc aacgttgtcc cgaggaacaa ccagatcatc
     7261 aaaaggatta tagcgacaac cacaccaaac accaatagcg tattcacact tttctttctc
     7321 atgtctttaa ctgatttatt cattttagaa taaacagccg gaacatgaat ttggttgtgt
     7381 acccttactc ttatttgttt ttccctaacg cctcgttcag cactttgttc ttagcgatcg
     7441 ttgcttggaa ttctttcaaa tagaaaggct caaaataagc cacattctca aaacgggcat
     7501 catcatatgc tttctgcgac aaggatgcca tatttacagc taatggatag ataccatcta
     7561 taaaacaggc attcggggaa gtgattaccg tctcacattt agcggcaccg tctccaaaga
     7621 aacaaacctt accgttctct aaaaaagaag catacgaatc agcatctacg atatcagcag
     7681 tcgtagcacg tatcgtgttg agatgggaat cataaatcga agagtagact tccatacgac
     7741 gggcatccaa catagcgcaa tacaagcaat cggcctcctc cttatttttc cggatagcgg
     7801 cagacgctaa aatatccagc gtatgaatac cgatcaaagg aataccgtac ccaaagcata
     7861 atcctttagc cacagacacc ccgatgcgta accccgtata agatccgggt ccgctactta
     7921 ccgccacggc atccagtttc atccctttcg acttcgcaac ctctaatgcc tcttccatat
     7981 aaacgcccaa taacgccgca tgagacggcc cctcgaagga agccttctca aagaccacct
     8041 cctccccttc cgacagggct actgaacata cggaagtgga tgtctcgata tttaagatca
     8101 atgacataat aattaactat taacaattga taattgaacg aacaaacaat ctcaatcctt
     8161 caatctgatt aggctgcgaa ggtatacaaa aattcattat actatcaagg cagccctatg
     8221 agaaacatct atttatgaga aaataaacat caaatctaaa aggaaaccac tatctttgcg
     8281 caaacttttg agaaaaatga tacaatcaat gactgggttc ggtaaggtta ctgccgagct
     8341 cccttcaaaa aaagtaaccg tagagataaa ggctttaaac agtaagcaat tggatttgtc
     8401 cacccgtatc ccttctatat acaaggataa ggaaatggag cttcggagcc tgttacttca
     8461 atctttggag cggggaaaag ttgagttcaa tatctttata gaatatatag gcaaagatac
     8521 tcctacacag atcaatcttg ccgccgtaga gaattattac aaccaaatca aggagatcgc
     8581 agagaaactg aatatcagcg ttccgaacga ttggttccag accttgctcc ggatgccgga
     8641 cgcaatcaag tccgagaccg tagaaccgga cgaatccgaa tggggggtgg ttttagaaac
     8701 ggtaaaggac gctatcaagc acctgtgtga tttccgtatc caagaaggag ccatgcttca
     8761 aaagcttttt gagcaaaaga tagccaatat cgccactctg ttgaaagaag tggagaaata
     8821 cgagggggaa cgtatcgaga aaatcaaagc tcgtatcatg gataacctgc aaaagatagc
     8881 cgagaaggac tatgacaaga atcgtttcga acaagaaatg atctattaca tcgagaagct
     8941 ggatgtcaac gaggaaaaga accgtttgga caaccacttg aaatatttta tctcaaccat
     9001 ggaatccggt cacggccaag gcaagaagct cggttttatc gctcaggaaa tggggcgtga
     9061 gatcaatacg ctcggatcaa agagcaacca cgccgagatg cagaagatcg tggtccagat
     9121 gaaagacgag ttggaacaaa tcaaggaaca ggtactaaac gtattataat aagattaacg
     9181 agaatggctg gcaaattaat tatcttctcc gcaccctcgg gttccggaaa atcaaccatt
     9241 attaattatc ttttgaaaca agatttacac cttcgtttct ccatctcggc taccagccgg
     9301 gctccgcggg gaaccgagaa gaatggtgtg gaatattatt tccttacgcc ggaagagttc
     9361 cgcagtcgta tcgctaatgg agacttcttg gaatatgagg aggtgtatac cgataaatat
     9421 tacggtacgt taaagagcga ggtagagcgt atcttgaatg aaggggacaa cgtgattttc
     9481 gatgtggatg tggtaggcgg atgcaatatc aagaaattct atggagaccg tgccctgtct
     9541 gtctttatcc aacctccttg catcgatgac ctacggaagc gattggaagg acggggaaca
     9601 gacagcccgg aagttatcga aagccgtatc gccaaggcag agtatgaatt agggttcacg
     9661 ggacagtttg ataaggttgt cgtaaacgat gatctggaga ctgcccaaaa agatgcgttg
     9721 aagatcattc gtgagttctt aaacaaatag cctatgccta atatattcaa gaatacccgt
     9781 tttatgatgg ggctttctat cgtttgtggg atagcgagcc tcgtattagg tggtatcagc
     9841 ctgtattata aggagtatat catcgggggt gccctgatat ttaatatatt catttgtttt
     9901 atcaactata agggttggca aaagaagggg taagtataaa tcggatgaga ctcaagaccg
     9961 gcatctacag tggatcgttc aatcccattc acataggcca tctcgccttg gcgaactggc
    10021 tatgtgagtt cgagggactg gatgaggtgt ggttcgtggt cacgcctcat aatccgctga
    10081 agaaaaagga tgacttgcta gatgactcac tacggttgga aatggcccaa gccgccattg
    10141 acggatatcc gaaattcaag gtctgcgata ttgagttcca cctgccgaaa ccttcttatt
    10201 ccattgatac cctacgagcc ttatccagta actatccgga tagggacttt tattttatca
    10261 tgggagccga taactggctg ctttttcccc gatggaaaga atatgaaaaa atactccaaa
    10321 actacaaact gctgatttat cc
//
