LOCUS       gnlProkkaBMPLKLLE_41   11754 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMPLKLLE_41.
ACCESSION   gnlProkkaBMPLKLLE_41
VERSION     gnlProkkaBMPLKLLE_41
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 20:37:46
            Original ID  :: gnl|Prokka|BMPLKLLE_41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11754
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11754
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6093:7840]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6094..7840
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11754
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11754
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(2..592)
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MAYFYEEPSRTFGEYLLVPGYSSAENVPTAVSLKTPLVKYRKGQE
                     ECPLQMNIPMISAIMQSVSGDKLAIALARQGGVSFIYGSQSIENEAAMVRRVKSFKAGY
                     VVSDSNLAPTATLHDVLELKARTGHSTIAITADGTPGGKLLGIVASRDYRVNHTPDDAC
                     VTTFMTPVEKLVTAPANTSLHDCNNIIWDNKINT"
     CDS             1211..2011
                     /locus_tag="ctg41_2"
                     /transl_table=11
                     /translation="MKTKLGIVGCGFLGIIVADAWKKGLLPDYELVGVTSRTRASAEKT
                     AANVGCAVCEDVDALLALEPEYIVEAASVESVRAMAIPVLKRGVNLVILSIGAFADLDF
                     YAQVKAAAVEGGAKVHLASGAIGGFDVLQTVTLMAQAQGLPETAGIETHTGAKGFRNTP
                     VWAEHLLTDTEKTTVFTGNAKQAIATFPRRVNVAVATSLATTGPEITGVTMHSVPGWVG
                     DDHCITAEIEGVKAVVDICSSTSAIAGWSAVSLLRNLSSPVCFY"
     CDS             2030..2926
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 97; E-value: 1.5e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_3"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 3.8e-18, bitscore:
                     55.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEKLVAIEPVSLIPSAEEELHRYAKEVVLYRDVPGSDAEMVRRI
                     GDADAVLLSYTSRMGKEVIAQCPNIRYIGMCCSLYSEESANVDIAYARTRGIQVLGIRD
                     YGDRGVVEYVLHELTGLLHGFGMPMLRDEPVEITGLKVGIVGLGVSGRMIADALQFMGA
                     EISYFARSAKPDAEAVGMTFKPLAQLLAESEVVFTCLNKNVLLLGENEFAQLGAGKVLF
                     NTSIGPGFDSAALEKWLDLPGTRFFCDTRAAAGPVAEDFFARENVRCANVSAGRTKQAF
                     VLLSKKVLDNIRTALGE"
     CDS             3147..3947
                     /locus_tag="ctg41_4"
                     /transl_table=11
                     /translation="MKTALTIAGSDSSGGAGIQADIKTMTANGVFAMSAITALTAQNTT
                     GVTAIFDTTPQFLAQQLDAVFTDIYPDAVKIGMVSSAPLIDTIAERLHFYGAKHIVVDP
                     VMVATSGAKLLQDDAVQALTEKLLPLAEVLTPNIPEAEILAGMSIANAADMEAAARTIS
                     ERYGCAVLCKGGHQINDADDLLWQGGTGKWFKGKRIANPNTHGTGCTLSSAIASNLAKG
                     YDLDTAVERAKAYISGCLSAMLDLGHGSGPMDHTFNLKGDFVRD"
     CDS             3940..4617
                     /locus_tag="ctg41_5"
                     /transl_table=11
                     /translation="MTDLPFVSALVQADLPVWEQCLQTEFLQKMENGTLSEDCFKSYLV
                     EDSLYLREYAKIFAWGMTKATTMAAMRTYYSLLSFVQENEDLTRLRYLEQYGLREADIQ
                     SLPLRPENRAYLDCMIDAARTGEGEAECLMACLPCMLSYGWLFQKLLQRSPAVKDTYYG
                     ALVLDYAGPGYDAACRAWAERAEAACTGLSPERAARCRAIFRACSEHELHFWEMCATPR
                     TDI"
     CDS             complement(4679..6097)
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="MSMTTPIVDFVRSYAKSGTARLHMPGHKGQSLLGFEPLDITEICG
                     ADELYAPEGIIAESEANATRLFGTVHSYYSTEGSSQCIRAMLFLALQGAPQNGKRPVLL
                     AARNAHKALLYAAALLDFDIRWLWPSAQAEGALCSCPVTAEALTGALHAMAQQGNTPFG
                     VYVTSPDYLGGVQDIPALAAVCRAQGVPLLVDNAHGAYLRFLPQNCHPIAQGAAMCCDS
                     AHKTLPVVTGGAYLHLAHDAPVQDEAAVRGALALFGSTSPSYLILQSLDACNAVLAGDY
                     PRRLVQCCAALEGLRRSLNKAAAARQCPVPLAVAGAQQEPMKLTLDAAALGCTGTALAD
                     ALRRAQLECEYADPRYVVLMFTPENPPQDYTRLQATMEQLLAAVPAGLPRPENRAGEFA
                     ALQQQAVQRCTIRQAVLGAQVRIPVHKALGRVCAMPTVSCPPAIPVAVSGEEITPAAIA
                     LMQRYGIEELSVLR"
     CDS             complement(6094..7545)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_7"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.6e-31,
                     bitscore: 97.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.7e-16, bitscore: 48.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.4e-17, bitscore: 52.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.8e-21, bitscore:
                     63.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFDMVKKLVAYCREQEKIHNKNFRFTMTTNGVLIDDDVIDFCNKECHNVVLSLDGRKEV
                     NDRFRVDCAGNGSYDRIVPKFQEFVKKRGDKNYYMRGTYTHYNTDFTNDIFHMADLGFT
                     ELSMEPVVCDPSDPSALTEADLPILKEQYEILAKEMIKRDREGRGFTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDPKYLLGDIWKGVTNTAVRDEFKHCNA
                     YARKECQDCWAKLYCSGGCAANSYHATGSITGVYEYGCELFKKRMECAIMIKVAENQEL
                     AAKGIEVPIELGSTCNACADGEACE"
     CDS             complement(7613..7840)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_8"
                     /sec_met_domain="TIGR03973 (E-value: 4.5e-26, bitscore:
                     80.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.6e-25, bitscore: 77.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISYYKIKAYRNYVRRDKILRVREVSIMERIKTIATRDLTKSVKT
                     GGCGECQTSCQSACKTSCGVANQQCENSNK"
     CDS             complement(8056..8343)
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRVPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGG"
     CDS             complement(9217..10977)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 252.9; E-value: 1.2e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_10"
                     /transl_table=11
                     /translation="MKQLISRRSFLKAAGVTAAAASMAIGAPAASACWYGDKSDVTILY
                     TNDVHTYIDKQSPKLTYAAIADLKQSYQNAGKDVLLVDAGDHVQGTAYGSMDEGASIIK
                     LMNAAGYDVATPGNHEFDYGMDRAKAIMKEADFPYLSCNWVDLRTTLRVLPSVKVFVRG
                     GRRIAFVGVTTPETFTKSTPAYFMDKAQRKYIYDIQGGEDGKKLYDAVQKAIDKAKLLA
                     DVVIGLGHLGVDPSSSPWTSEEVIAHTSGFDAFIDGHSHTVMENKQVQDASGKAVTLTQ
                     TGSYFANVGEMTIAADGTITTKLIPTHEGMDAGIAAMQTSWVNTVDDMLGEKIAVGDSD
                     FYVSDPATGKRRIRSAETNLGDFVADGIYTYFNEVEKLHCDVAIMNGGGIRADVPAGDW
                     TFKTCKQISPFGNVACLMSVTGKQIQDALEFAARFAGEDGKENGGFLQVAGATYEIHTD
                     IPNTVQTDEKNVWIGSATGTPRVQNVKIYDKASGSYLPLDPGATYALAGMNYTLRNLGD
                     GFAMFDGAELIKDYVSEDYLVMSTYAMIFDGADAAGLPHLSSANSPLAAYPGYLLNYEQ
                     PYGAGRITIL"
     CDS             complement(11254..11754)
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MPMRDCTGREICMEWLYHIGVPEDQIAELAEHSANTVPVMMPYID
                     AFFMPRAMGDRPDVVPEGAVNFAFLGQFAETARDTIFTTEYSMRTGMEAVYTLLNIDRG
                     VPEVWGSTYDVRALIDATVKLRDGKKITDMDLPLIPRLALKEALKKIEGTDLEKFLKEY
                     NAI"
ORIGIN
        1 gggtgttgat cttgttgtcc cagatgatgt tgttgcagtc gtgcagggag gtgttggccg
       61 gagcggtgac cagcttttca acgggggtca taaaggtggt aacacaggca tcgtccgggg
      121 tgtggttgac gcggtaatcg cgggaagcca cgatgcccag cagcttgccg cccggagtgc
      181 cgtcggcagt gatggcgatg gtggagtggc cggtgcgtgc cttcagctcc agcacatcat
      241 gcagggtggc agtgggagcc agattggaat cggacaccac ataaccggcc ttgaagctct
      301 tgacgcggcg caccatggca gcctcgttct cgatgctctg agagccatag ataaaggaaa
      361 cgccgccctg acgagccagt gcaatggcca gcttatcgcc ggagaccgac tgcatgatgg
      421 cgctgatcat ggggatattc atctgcagcg ggcactcctc ctgtcccttg cggtacttga
      481 ccagcggggt cttcaggctg accgccgtgg gcacattctc cgcagaggaa tagccgggga
      541 ccagcaggta ctcgccaaag gtgcgggagg gttcttcgta gaaataagcc ataatcaaac
      601 tccttttctc ttagggtgta tctgatacaa atcagcatca aaatcattca tgtttgctgc
      661 ttataaattg attgtatata ctttaccaca aagcccgcaa gaatacaaac ccctgccgcg
      721 ccaaacttta taattgtcct ttgcggaaaa acagacaaat tgacaagcgt ttttaggcat
      781 tggtcatact ttggtttttg aagtatcact tttacgggca aaacagggct tgcagaatgc
      841 aaaaaagctc gtccgaaaca ccggacgagc ccttttgcac acgaagcggg acactgcctg
      901 tgcggcgcat gggtcatagc tgtgaaggag aacagccgga ggaggaggac ccgcgcccag
      961 tatcccaaaa acaagaagaa aaagatttca cacacagcct tggggctttg cccttgctgt
     1021 aaccatattg taactctttt gaaaccattt tgcaataggg ttttgtaatt tttttgtaat
     1081 ttattttgtt aactttttat gtcctgcccc gccgggctgc cgcaaacatt atttcccttt
     1141 ttgtacccgg tatggtatac tggctatgaa tatgctgcca caggcagaaa aaaggagttt
     1201 aggatacggt atgaaaacaa aattgggtat tgtgggctgc ggatttctgg gcatcatcgt
     1261 ggctgacgcg tggaagaagg gtctgctgcc ggactacgag ctggtgggcg tgaccagccg
     1321 cacccgcgct tcggctgaaa agaccgccgc caatgtcggc tgcgccgtct gtgaggacgt
     1381 ggacgcactg ctggcacttg agccggagta catcgtggag gcggcctcgg tggagtcggt
     1441 gcgcgctatg gccatcccgg tgctgaagcg gggcgtcaat ctggtcattc tgtccatcgg
     1501 tgcctttgcg gatctggatt tctacgcaca ggtcaaggca gccgccgtgg agggcggtgc
     1561 caaggtgcac ctggccagcg gtgccatcgg cggctttgac gtgctgcaaa ctgtcaccct
     1621 gatggcacag gcgcagggtt tgccggagac tgccggcatc gagacccata ccggtgcaaa
     1681 gggcttccgc aacaccccgg tgtgggcaga gcatctgctg accgacaccg aaaagaccac
     1741 cgtgttcacc ggcaatgcca agcaggccat tgccaccttc ccccgccggg tgaacgtggc
     1801 ggtagctacc tctctggcca ccaccggccc cgagatcacc ggcgtgacca tgcactccgt
     1861 gcccggctgg gtgggcgatg accactgcat cactgccgag atcgagggcg tgaaggctgt
     1921 ggtagatatc tgctcttcca ccagcgccat tgcgggctgg agcgccgtct ctctgctgcg
     1981 caatctgtcc tcacccgtct gcttctacta atataaggag gagtccgtca tgtttgaaaa
     2041 gcttgttgcc attgagcctg tcagcctgat cccctctgcc gaggaggaac tgcaccgcta
     2101 cgccaaagag gtggtgctgt accgggacgt gcccggcagc gacgccgaga tggtgcgccg
     2161 catcggggac gccgacgccg tgctgctgag ctacacctcc cgcatgggca aggaagtcat
     2221 tgcgcagtgc cccaacatcc gctatatcgg catgtgctgc agcctgtact ctgaggagag
     2281 cgccaacgtg gatattgcct acgcacgcac ccggggcatt caggtgctgg gcatccggga
     2341 ttacggcgac cgcggcgttg tggagtatgt tctgcacgag ctgaccggtc tgttgcacgg
     2401 ctttgggatg cctatgctgc gggacgagcc ggtggagatc accggcctga aggtgggcat
     2461 cgtggggctg ggcgtttccg gccggatgat cgccgatgcg ctgcaattta tgggcgcaga
     2521 gatcagctac tttgcccgca gcgcaaagcc ggatgccgag gctgtcggta tgacctttaa
     2581 gccgctggct cagctgctgg ctgagagcga ggtggtgttc acctgcctga acaagaacgt
     2641 actgctgctg ggcgaaaatg agtttgccca gctgggtgca ggcaaggtac tgttcaacac
     2701 ttccatcggc cccggctttg actccgctgc gctggaaaag tggctcgatc tgcccggcac
     2761 ccgcttcttc tgcgacaccc gcgccgctgc aggccccgtg gccgaggact tctttgcccg
     2821 ggaaaacgtg cgctgcgcca atgtatccgc aggccgcacc aagcaggcct ttgtgctgct
     2881 gagcaaaaag gtactggaca acatccgcac tgcactgggc gaataagcgg tgcgtttgcg
     2941 cggcctgttt ttcttgcatc ttttccccga ttgtggtatg ctttctagta taaaaaggga
     3001 gcccgtgcaa gcgggctgag agtgggctgt attgccctga cctgtgacct gatttggatc
     3061 atgccaacgt agggagatag cgcttttatc tgcggatatg tctttgcggg catatccgca
     3121 tttttgctgc aaaggagcat ttacccatga aaactgcatt gaccattgcc ggcagtgatt
     3181 ccagcggcgg cgccggaatt caggccgata tcaagaccat gaccgccaac ggcgtgtttg
     3241 ccatgagcgc catcaccgcc ctgacggcac aaaacaccac cggcgtgacc gccatttttg
     3301 acaccacacc gcagtttctg gcacagcagc tcgatgccgt gttcaccgac atttacccgg
     3361 atgcggtaaa aatcggtatg gtatcctctg ccccgctcat cgacaccatc gccgagcggc
     3421 tgcattttta cggcgcaaag cacattgtgg tggaccctgt gatggtggcc acctccggtg
     3481 caaagctgct gcaggacgat gccgtgcagg cgctgaccga aaagctgctg ccgctggccg
     3541 aggtgcttac ccccaacatc ccggaggctg agatcttagc cggcatgagc attgccaatg
     3601 ccgccgacat ggaagccgct gcccgtacca tcagcgagcg ctacggctgt gccgtgctgt
     3661 gtaagggcgg ccaccagatc aacgatgctg acgacctgct gtggcagggc ggcaccggca
     3721 agtggttcaa gggcaagcgc attgcaaacc ccaacaccca cggcaccggc tgcaccctgt
     3781 ccagcgccat tgcttccaat ctggccaagg ggtatgacct tgacaccgcc gtggagcgcg
     3841 ccaaggccta catttccggc tgtctgtctg ccatgctgga cttagggcat ggctccgggc
     3901 ccatggatca caccttcaac ctgaagggag attttgtccg tgactgacct gccctttgtc
     3961 tcggcgctgg tacaggccga cctgcctgtg tgggagcagt gtttgcagac cgagtttttg
     4021 caaaagatgg aaaacggcac cctgagcgag gactgcttta aaagctacct tgtggaggac
     4081 agcctgtatc tgcgggagta cgccaaaatt tttgcgtggg gcatgaccaa ggccaccacc
     4141 atggctgcca tgcgcaccta ctattccctg ctgtcctttg tgcaggagaa cgaggacctg
     4201 acccggctgc ggtatctgga gcagtacggt ctgcgggaag ccgatatcca atccctgccc
     4261 ctgcggccgg agaaccgcgc ctatctggac tgcatgattg atgctgcccg caccggcgag
     4321 ggggaagctg agtgcctgat ggcctgcctg ccctgtatgc tgagttatgg gtggctattc
     4381 cagaagcttt tgcagcgctc ccccgccgta aaggacacct actacggcgc actggtgctg
     4441 gactacgccg gccccggcta tgatgccgcc tgccgcgcat gggcagaacg cgctgaagca
     4501 gcctgcaccg gcctttcgcc ggagcgtgcc gcccgctgcc gcgcgatctt ccgcgcctgc
     4561 tcggagcacg agctgcactt ctgggagatg tgtgcaacac cccggacgga tatttaagaa
     4621 taaatataga gaacccggaa gttccgcaga ccttccgggt tctcttctta taaaatcttt
     4681 atcgcagcac cgagagttcc tcgatgccgt agcgctgcat cagggcgata gccgccgggg
     4741 tgatctcctc gccgctgacc gccacaggga tggcgggcgg gcaggacacc gtaggcatgg
     4801 cgcacacccg ccccagcgcc ttgtgtaccg ggatgcgcac ctgtgcgccc agcaccgcct
     4861 gccggatggt acagcgctgc accgcctgct gctgcaaggc ggcaaactct cctgcccggt
     4921 tctcggggcg gggcagcccg gcaggcacag cagccaaaag ctgttccatc gtagcttgca
     4981 ggcgcgtgta gtcctgcggc gggttttccg gggtgaacat cagcaccaca taacgggggt
     5041 ctgcatactc gcactccagc tgtgcgcggc gcaaagcatc tgccagcgct gtgccggtgc
     5101 agccaagggc ggcggcgtcc agcgtaagct tcatcggctc ctgctgtgcc ccggcaactg
     5161 ccagcggcac cgggcactgc cgcgccgctg cggccttatt caggctgcgg cgcagacctt
     5221 ccagcgccgc gcagcactgc accagccgcc gggggtagtc ccctgccagc accgcattgc
     5281 aggcatccag cgactgcaaa atgaggtaag aggggctggt agagccgaac agcgccagcg
     5341 ccccccgcac agccgcttcg tcctgcacag gggcatcgtg cgccagatgc agatacgcgc
     5401 cgccggtgac caccggcagg gtcttgtggg cagagtcgca gcacatggcc gcgccctgcg
     5461 cgatggggtg gcagttttgc ggcagaaagc gcaggtaggc cccgtgggcg ttatccacca
     5521 gcaaaggcac gccctgcgcc cggcagacag cggccagcgc cggaatatcc tgtactccgc
     5581 ccagataatc cgggctggtg acgtatacgc caaagggggt gttcccctgc tgtgccatcg
     5641 cgtgcaaagc ccctgtcagc gcttcggctg tgacggggca gctgcacagt gcaccctctg
     5701 cctgcgcaga cggccaaagc catcggatgt caaaatccag cagcgccgcc gcgtacagca
     5761 gcgccttgtg ggcattgcgg gcggccagca gcaccgggcg cttaccgttt tgcggtgcgc
     5821 cttgcagcgc cagaaacagc atggcacgga tgcactgaga cgagccctca gtgctgtaat
     5881 agctgtgcac cgtgccgaac agccgggtgg cgttggcttc actctcggca ataatgccct
     5941 ccggcgcgta aagctcgtct gcgccgcaga tctcggtgat atccagcggc tcaaagccta
     6001 aaaggctctg ccccttgtgg ccgggcatgt gcagccgggc ggtgccggac tttgcatagc
     6061 tgcgcacaaa atccacgatg ggggtggtca tgctcattcg caggcttcgc cgtcagcgca
     6121 ggcgttgcag gtagagccca gctcaatggg cacctcaata cccttagcag ccagttcctg
     6181 attctcggct accttgatca tgatggcgca ctccatgcgc tttttgaaca gctcgcagcc
     6241 gtactcgtac acgccggtaa tgctgccggt ggcgtggtag gagttggcag cgcagccgcc
     6301 ggagcagtac agctttgccc agcagtcctg acactccttg cgggcgtagg cgttgcagtg
     6361 cttgaactca tcccgcacag cggtgttggt aacgcccttc cagatatcgc ccagcaggta
     6421 cttggggtca cccacgaact ggtggcaggg gtacagatcg ccccaagggg taacagccat
     6481 gtactcggtg ccggagccgc agccggagat gcgcttatag atgcaggggc cgccggtcag
     6541 gtcgatcatg tagtggtaga aggtaaagcc tctgccctcg cggtcgcgct tgatcatctc
     6601 cttggcaagg atctcgtact gctccttcag gatgggcagg tcggcctcag tcaaggcgct
     6661 ggggtcgctg gggtcgcaga ccaccggctc catgctcagc tcggtaaagc cgaggtctgc
     6721 catgtggaag atatcgttgg taaagtcggt gttatagtgg gtataggtgc cgcgcatata
     6781 gtagttcttg tcgccgcgct tcttgacgaa ctcctggaac ttgggcacga tgcggtcgta
     6841 gctgccgttg cctgcgcagt ccacgcggaa gcggtcgttg acctccttgc ggccatccag
     6901 actcagcacc acattgtggc actccttatt gcagaagtcg atgacgtcgt catcaatgag
     6961 cacaccgttg gtggtcatgg taaagcggaa gttcttgtta tggatcttct cctgctcgcg
     7021 gcagtaggcc accagctttt tgaccatatc aaagttcatc agcggctcgc cgccaaagaa
     7081 gtccacttcc agattgcggc gggtgccgct gttctcgatg aggaagtcca tggcgcgctt
     7141 gcccacctca aagctcatca gggcgcggtc gccatggtag cgtccctgcg aggcaaagca
     7201 gtaagagcag ctcaggttgc agctatgggc aacgtgcagg cacagcgcct ttaccacagt
     7261 gttgcggttt ttaaagtcga aggccatgtc cttatagaca tccgggctcc acagcttgcc
     7321 gttttccttc aggctggtca cgtcgtcgat gcactggcgc agatcctcct cggtcacgtc
     7381 cgggcggctg ccgtactttg ccagcatggc ggcaacgatc tcgtctgcgg tatgctccgg
     7441 gtacatggcg atgacatcgt aggccacctc gtccacaacg tgcaccgagc cgctgcaggt
     7501 gtccagcacg atgttataac cgttcaattg atactgatgt accattttac actccattcc
     7561 agattacaca aaaaaatgcc gcccggcaaa ggcggcatag ggtttgcaaa aattacttgt
     7621 tgctgttctc gcactgctgg ttagccacgc cgcaggaggt cttgcaggcg gactggcagg
     7681 aagtctggca ctcgccgcag ccaccggtct taacgctctt ggtcaggtca cgagtagcaa
     7741 tagtcttaat acgctccatg atagaaacct ctctaactct caaaatttta tcgcgccgga
     7801 catagttccg gtacgctttt atcttgtaat aggatatcac gcagcgcgcc ttttgtcaag
     7861 attttttcgc taaggcaata ccgcataatt ctaggtgccg atacggcgag tgaggtgcgg
     7921 cagatgctaa gccaaaagcg cagataatac tttgtgtatt atcgagcatt ttggcaacgc
     7981 agatgccgtg ccgcaaccgc cggagtggtg cttaagccgt aaggcgggaa ttgtgcggtg
     8041 ttgccctaag cctttttacc cgcccatggg ctggtagcgg gtaagcaccg tatgcagccc
     8101 cagctcccgg gcgcgcgcca gtaagtaccg gtagcggcac aaaagcgcct gccgctcgta
     8161 gatgcgctgc tcgatgaggt ccgtatccac ctccatatca aacatcatct cgttgcgctt
     8221 caaacagaac aggcattcct tcagttcctc ctccagctcc gggtggtagc gctcgtgctc
     8281 ggtatcccgc gggacgcggg gcgaaagcag ggtctgggcg ttttgtgtgg ttcgttccgg
     8341 cataggcatc ctccttctgg tactttgcaa ggttttgtac cttccagtat aggcggtgcg
     8401 gtgcgcagaa cctgccgaag tgtggcagcg ctccggcata gattatccgg cgctgctgcg
     8461 gcattttcca aaaaagtaca acttttttca aaaatatgct tgacaactcc gggcttttcc
     8521 cgtataatag cacacgttga gcggctcacc ccgcaaaaca caacagaata ttggggattt
     8581 gcatagtggt agtgcggtag actctgactc tacttgtggg agttcgattc tctcatcccc
     8641 aaccagatta aagccatctg aagaagttca ggtggctttt ctgtttatat cattccgaac
     8701 cacagccgca aggccgtgac tcttcaaaac ttgaagagtc ataactctat taccactttg
     8761 gatttttgaa gagtgacgaa aaagaagcgc atcagcgttt aaaagttcac tcttcaagat
     8821 gaagagtcat ggcctgaaaa cgcagttttc tttgcttttt gttcatgact cttcaaaacc
     8881 cctgtgggtc atagggaact tttgaagagt cacccctgcc ggggcgggac gatttagaat
     8941 gcgctccgcg ttcgctctgc gcataattag cggaattagt tttttactcg agattcagaa
     9001 aagcctgcgg gcttttctga atctcctttt caccagtggg gtcgtaacgg tcaactgcat
     9061 ttgcaattca gaccaccatt taaccattgc agccctcccc gtgaaaatgg gatagcggag
     9121 cgcatttcca atcgttcgta ctgcacaaaa aaccgggcag cccgcagact gcccggtttt
     9181 tgctatacag ttgacctgcc ctgatagggc tttcttttac agaatggtga tgcggcctgc
     9241 gccgtaaggc tgctcgtagt tgagcaggta gccggggtat gcggccagcg ggctgttggc
     9301 gctggacagg tgcggcagac ccgcagcatc tgcgccgtca aaaatcatag cgtaggtaga
     9361 catcaccaga taatcctcgg acacatagtc cttgatcagc tctgcgccgt caaacatggc
     9421 aaagccgtcg cccagattgc gcagggtgta gttcatgccg gccagcgcgt aggtagcgcc
     9481 cgggtccagc ggtagatagc tgccggaagc cttatcgtag atcttcacgt tctgcacgcg
     9541 cggggtgccg gtggcgctgc cgatccagac gttcttctcg tcggtctgca cagtgttggg
     9601 gatatcggtg tggatctcgt aggtagcacc ggccacctgc aggaagccgc cgttctcctt
     9661 gccgtcctcg cctgcaaagc gagctgcaaa ctccaatgcg tcctggatct gcttgccggt
     9721 gaccgacatc aggcaggcca cgttgccaaa ggggctgatc tgcttgcagg tcttgaaggt
     9781 ccagtcgcct gcaggcacat cggcgcggat gccgccgccg ttcatgatgg ccacatcaca
     9841 gtgcagcttt tccacctcgt tgaagtaggt gtagatgccg tcagccacaa agtcgccgag
     9901 gttggtctcg gcagagcgga tgcggcgctt gccggtggcg gggtcagaga cgtagaaatc
     9961 gctgtcgccc acagcgatct tctcgcccag catatcgtcc acggtgttca cccagctggt
    10021 ctgcatggcg gcgatgcctg cgtccatgcc ctcgtgggtg gggatgagct tggtggtaat
    10081 ggtgccgtcc gcagcgatgg tcatctcgcc aacgtttgca aagtaagagc cggtctgggt
    10141 cagggtgaca gccttgccgg aagcatcctg cacctgcttg ttctccatta cggtatggga
    10201 gtggccgtcg ataaaggcgt caaagccgct ggtgtgggca atgacttcct cactagtcca
    10261 cggagaggaa gaggggtcta cgcccagatg gcccagaccg atgaccacgt ctgccagaag
    10321 ctttgcctta tcaatggcct tctgcacggc gtcatagagc tttttgccgt cctcgccgcc
    10381 ctgaatatcg tagatgtact tgcgctgtgc cttatccata aagtaggccg gggtggactt
    10441 ggtaaaggtt tcgggggtgg tcacgcccac aaaggcaatg cgtctgccgc cgcgcacgaa
    10501 caccttgacg gagggcagca cacgcagcgt agtgcgcagg tctacccagt tgcaggacag
    10561 gtacgggaaa tcggcttcct tcatgatggc cttggcacgg tccatgccgt agtcaaactc
    10621 gtggttgccg ggggtggcga catcgtaacc ggcagcgttc atcagcttga tgatggaggc
    10681 accctcgtcc atggagccgt aggcagtgcc ctgcacatgg tcgcctgcat ccaccagcag
    10741 cacgtcctta ccggcgttct gatagctctg cttcaggtcg gcaatagcgg cgtaggtcaa
    10801 cttggggctc tgcttgtcga tgtaggtatg gacatcgttg gtgtacagga tggtaacgtc
    10861 agacttgtca ccataccagc aggccgatgc ggcaggcgca ccgatggcca tggatgcagc
    10921 ggcagcggtc acaccagcag cctttaaaaa gctgcgacgg gaaataagtt gtttcacagg
    10981 aaaacgacct ccttttattt ttggcgtatc gcatttgagg caggctcttc cctcctgccc
    11041 tttcaatagc tctagcatag cacagaacgc cgccgcaaac aagccaaaat cattcttttg
    11101 gcacaaatta ttttcacgct ctgctttatt ttgacgcata ttgtaccatt tttacacaaa
    11161 aaagacctcc ccgtgccctg tcgcagagca gcggagaggt cttttttagg gggtgttgac
    11221 ccgttgccgg gtctatcgga ggagagggaa atatcagatg gcgttatact ccttgaggaa
    11281 cttctcaagg tcggtaccct cgatcttctt caaagcttcc ttcaaagcca gacgcgggat
    11341 cagcggcaga tccatgtcgg tgatcttttt gccgtcgcgc agcttcacgg tggcatcgat
    11401 cagggcgcgc acatcgtagg tgctgcccca gacctcgggc acgccgcggt cgatgttcag
    11461 cagggtgtac acggcctcca taccggtgcg catggagtac tcggtggtaa agatggtatc
    11521 gcgggcggtc tcggcaaact ggccaaggaa ggcaaagttc acagcaccct cgggcacaac
    11581 atcgggacgg tcgcccatgg cacggggcat gaagaaggca tcgatatagg gcatcatcac
    11641 aggcacggtg ttggcgctgt gctctgccag ttcagcgatc tgatcctcgg gcacgccgat
    11701 gtggtacagc cactccatgc agatctcgcg gccggtgcag tcacgcatgg gctt
//
