LOCUS       c00198_gnlPro..         4000 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAJBLOHH_198.
ACCESSION   c00198_gnlPro..
VERSION     c00198_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:17:36
            Original ID  :: gnl|Prokka|CAJBLOHH_198
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4000
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4000
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3999]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3999
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4000
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4000
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..539
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg198_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.8e-53, bitscore:
                     167.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VYVTDVGQHQMWAAQYLRHTKSRGFITSGGLGTMGFGYGAAIGAQ
                     MALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIITVIFNNSVLGMVRQWQTSFYGKR
                     YSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFADALQQKGPTWIECIIDKDEKVL
                     PMIPGGGDINDIIME"
     CDS             555..1118
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg198_2"
                     /sec_met_domain="ALS_ss_C (E-value: 5.1e-29, bitscore:
                     88.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             1218..2237
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg198_3"
                     /sec_met_domain="IlvN (E-value: 2.4e-75, bitscore: 239.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3e-66, bitscore: 210.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHENFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             2404..3999
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg198_4"
                     /sec_met_domain="ILVD_EDD (E-value: 7.6e-218, bitscore:
                     712.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELEHPLIGVVSAYSEIVP
                     GHMNLDKIAEAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGTYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLAKHAGMAVMEMVRKGITARQIINERSIRNALTCDMALGCSTNTVLHLLAIAYEA
                     GVPIDLKLFNEISAKTPNLCHLAPAGPTHMPDLYAAGGIPAVQAELAKKGLLDLDVPTV
                     TGKTLGENIKGAHILNEKAIRPIENPYSETGGLQILWGNIAPDGCVVKRSAVAPEMQKH
                     AGPARVFNSEEEAIAAIYAGKIVPGDVVVIRYEGPKGGPGMREMLNPTSALAGMKLDKT
                     VALITDGRFSGASRGAAIGHVSPEAASGGPIGLIEEGDTISIDIPNASITLEVSDAVLA
                     ERKAKYVAPEPNIKT"
ORIGIN
        1 ccgtgtatgt taccgacgtg ggtcagcacc agatgtgggc ggcgcagtac ctgcgccaca
       61 ccaagagccg tggctttatc accagcggcg gcctgggcac catgggcttt ggctacggcg
      121 ctgccattgg tgcccagatg gcactgggac gccagcagcg tgtggtgatg tttaccggtg
      181 acgcctcctt ccacatgaac ctgaacgaag cctgcaccgc cgtcagctac gagctgccca
      241 tcatcacggt catcttcaac aactcggtgc tgggcatggt gcgccagtgg cagactagct
      301 tttacggcaa gcgttacagc cagaccgacc cccaccgcaa gaccgatttt gtcaagctgg
      361 cagacggctt tggcctgaag ggctaccgct gcaccaacct gccggagttt caggaagcct
      421 ttgcagatgc cctgcagcag aaaggcccca cctggatcga gtgcatcatc gacaaggacg
      481 aaaaggtgct gcccatgatc cccggcggcg gcgatatcaa cgacatcatc atggaataag
      541 gaggacacag catcatggaa tctgatcagc gtagggtcat cagcctgctg gtggacaacc
      601 agagcggcgt tctggcccgg gtgtccagcc tgttctgccg ccgcggcttc aatatcgaca
      661 gccttacggt gtccgccacc aacgacccgg cagtcagccg catcacagtg accattacca
      721 gcgatgaaaa ggccttgcag cagctggtat tgcagaccga gcggctggaa gtcacccggc
      781 aggtgttcgt gctggacagc gaaaaagcgc tggagcggga gctgctgctg ctcaaggtgg
      841 aatcggacgt gcacaaccgc acagagctgc gggagatcgc ctgcatctac aaggcaaaga
      901 tcatcgatct ttccccggac agcatggtgt ttgagttgat cggccggccg gacaagctgg
      961 acgctttcct gaaaatgttc gagggctaca acatccttga gcagtgccgc accggcgtta
     1021 ctgcactgga gcgcggcggg atgcaccagc atatccagaa accgccgcag gaggtgcgct
     1081 ccgtccagct gcccccgccg ggcgcaagac gggcataaat cacattgctt ttccgctcag
     1141 ggtgagcgaa agatagaaca gagcatacaa gaccggaaga taaaacaacc agaaaaagta
     1201 aaaggagact aacgattatg gctatcaaga aatactacga ttccgactgc aacctcggcg
     1261 tgctggacgg caagaccgtc gctgttatcg gcttcggcag ccagggtcat gcacactctg
     1321 agaatctggc cgagagcggc gtcaacgttg tggtcggcct gcgcaagggc tctgcccact
     1381 gggcaaaggc ttctgagttc gctgccaccc acgaaaactt caaggtcatg gaagtagaag
     1441 aggctgccaa ggccggcgat gttgtcatga tgctggtgcc cgatgagctg tgcgccgata
     1501 tctacaacac gcaggttgct ccctacatga ccgagggcaa ggcactggcc tttgcacacg
     1561 gcttcaacat ccacttcaag accatcaccg ctcccaagaa cgtggacgtc atcatgatcg
     1621 ctcccaaggg ccccggccac atcgtgcgcc gcctgtacac cgagggcgag ggctgcccct
     1681 ctctgatctg cgtggagcag gactacaccg gtaaggccaa ggatatcgca ctggcttatg
     1741 cttctggcat tggcgcaggc cgtgcaggca tcctgcagac caccttcaag gaggagaccg
     1801 agaccgatct gttcggcgag caggccgtgc tgtgcggcgg cgtttccgag ctgatccacg
     1861 ccggtttcga tacgctggtg gaggccggct acgagcccga gatggcctac tttgagacct
     1921 gccacgagat gaagctgatc gttgacctga tcaacgaggg cggcttctcc aagatgcgct
     1981 actccatctc caacactgcc gagtacggcg actaccgcac cggcaagcgc ctgatcaccg
     2041 aggagacccg caaggagatg aagaaggtcc tgaccgagat ccaggacggc acctttgctt
     2101 ccgagttcct gaccgagatg agccccaagg gcggccgcaa ggtgcacttc ctcgccaagc
     2161 gccgtatgga ggctgagctg cccatcgaga aggtgggtgc tgagctgcgc agcatgatga
     2221 gctggctgaa gaagtaagag gagaaccctc tcagaccgct tttcggcggt cagctccccc
     2281 gaaaggggga gtttttgttg aaaagggaac cttatagctc ctccgcgaaa acctctccct
     2341 ctcgggagag gtggcacgat acagccgtga cggagagggc tttatcagaa aagaggattt
     2401 gcaatgagaa gtgacaatgt gactaagggc tcggagcgcg cgcccaaccg cagcctgttt
     2461 tatgcgctgg gctacacccc ggaggagctg gagcaccccc tcatcggcgt ggtaagcgcc
     2521 tacagcgaga tcgtgcccgg acacatgaat ctggataaga tcgccgaggc cgtcaaagcc
     2581 ggtgtgcaga tggccggtgg tacccccatc ctgatccccg ccatcggcgt atgcgatggc
     2641 atcgccatgg gtcatgtggg catgaagtac tctctggcct cccgcgagtt gatctgcgac
     2701 agtgtggaga ccatgctgat ggcacaccag ctggacggcc ttgtgctggt gcctaactgt
     2761 gataagatcg tgcccggcat ggtgatggca gcggtgcgca tggatgtgcc cgccgtggtc
     2821 tgctccggcg gccccatgct ggccggtact tacggcggcg aggaagtgag cctttccaag
     2881 atgttcgagg ccgtgggtgc ctataaggcc ggtatgatca ccgacgagca gctggaggac
     2941 tgcacctgca actgctgtcc cagctgcggc agctgctccg gtatgtacac cgccaacagc
     3001 atgaactgcc tgtgcgaggc catcggcatt gccctgcccg gcaacggcac catcccggct
     3061 gtgtactcca agcgtctgca gctggcaaag cacgccggta tggccgtaat ggagatggtg
     3121 cgcaagggca tcaccgcgcg ccagatcatc aacgagcgct ccatccgcaa cgcactgacc
     3181 tgcgatatgg cactgggttg ctccaccaac acggtgctgc acctgctggc tatcgcctac
     3241 gaagccggtg tgcccatcga cctgaagctg ttcaacgaga tcagcgccaa gacccccaac
     3301 ctgtgccatc tggcaccggc aggccccacc catatgccgg atctgtacgc agcgggcggc
     3361 atcccggcag tacaggcaga gctggcaaag aagggcctgt tggatctgga tgtgcccacc
     3421 gtcaccggca agactcttgg cgagaacatc aagggtgccc atatcctgaa cgaaaaggcc
     3481 atccgtccca tcgagaaccc ctactctgag accggcggtc tgcagatcct gtggggcaac
     3541 attgccccgg acggctgtgt ggtcaagcgc agcgccgtcg ccccggagat gcagaagcac
     3601 gcaggcccgg cgcgggtgtt caacagcgag gaggaagcca tcgccgccat ctacgcgggc
     3661 aagatcgtcc cgggcgatgt ggtggtcatc cgctacgaag gccccaaggg cggcccgggc
     3721 atgcgggaga tgctcaaccc cacctctgcg ctggcaggca tgaagctgga taagacggtg
     3781 gccctcatca cggatggccg cttctccggc gcatcccgcg gtgctgccat cggccatgtc
     3841 agcccggagg cggcctccgg cggccccatc ggcctgatcg aagaagggga taccatttcc
     3901 attgatatcc ccaacgcctc catcacgctg gaggtcagcg atgcagtgct ggccgagcgc
     3961 aaggcaaagt acgttgcgcc cgagcccaac atcaagaccg
//
