LOCUS       gnlProkkaKIJMFKND_32   12410 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIJMFKND_32.
ACCESSION   gnlProkkaKIJMFKND_32
VERSION     gnlProkkaKIJMFKND_32
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 16:20:30
            Original ID  :: gnl|Prokka|KIJMFKND_32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12410
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12410
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2056:2410]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2057..2410
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12410
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12410
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..98
                     /locus_tag="ctg32_1"
                     /transl_table=11
                     /translation="MKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             127..492
                     /locus_tag="ctg32_2"
                     /transl_table=11
                     /translation="MLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKTTDFLEKA
                     TWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEAPQSEAPAA
                     TTPAETPAPAAEAPAAE"
     CDS             646..2037
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 101.4; E-value: 7.2e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg32_3"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFVFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             2057..2410
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_4"
                     /sec_met_domain="PqqD_RRE (E-value: 3.8e-10, bitscore:
                     30.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.8e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(2418..3452)
                     /locus_tag="ctg32_5"
                     /transl_table=11
                     /translation="MMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKTEIEIVLQA
                     TKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKMKDKTV
                     APLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSAKMAEL
                     VAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKKEPKTF
                     TIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKKKVDGV
                     AYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTATGGLIK
                     VDRE"
     CDS             complement(3538..4665)
                     /locus_tag="ctg32_6"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDNPIPHASLEAVGIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             complement(4767..7739)
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MEDIFSKRKTLRTIKADTSDYFIPLFHTLAVFLSTKETIITKRFL
                     EHIMKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFNKNGVKDVYEDP
                     SAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLWKDGIGAIDEHL
                     NGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNEGIRGVESYRAT
                     NFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGES
                     PYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQMSPREVENIHIY
                     PFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVVSDSDAVEYLYT
                     KHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEEVINDRVRDILR
                     VKFLIGLFDAPYQTDLADADREVEKEENEAIALQASRESIVLLKNAGELLPLDINSTKK
                     IAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGCDLVDAHWPESE
                     IIDYPLTDDEQAEIDKAVENARQADVAIVVLGGGQRTCGENKSRTSLDLPGRQLQLLQA
                     IQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADILFGDYNPGGKLT
                     VTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGLSYTTFEYSDLD
                     ITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNLAGFQRIHLEPG
                     EAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLTVEDYQTRAKAI
                     EAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAIAFTRDN
                     NLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRVSIAEVK
                     F"
     CDS             9020..9505
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MKIHEGKCTEKILKERERIGNRLAILRKKRNMTQEELANLCGVNR
                     VNIAKIEKGAYNVSIDILSKVTSALGFVIDIKVDSSVCPTHFSQRKPVKLVIGEDYYVS
                     FGNNEAHRCKLVDIPEMYQGQRIKIETPTPRGSITHILFADEIGTTPDEAVMNQVTM"
     CDS             complement(9587..9688)
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MIPNHQFKIIYSEETIKFLNSPDERGGVETLIN"
     CDS             complement(9705..10535)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 57.6; E-value:
                     2.1e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_10"
                     /transl_table=11
                     /translation="MDNQTQEGTKNMQKRHTDRESYFGEQSQTSKNYYIPYIKEVIGHI
                     PDKVLEVGCGEGGNLLPFAEAGCRVMGVDIDATRIEQARTFFAQRHQQGQFIATDIFQL
                     KDKATNFPLILLHDVIEHIRDKERFLSGLQKHLSADGAIFVGFPAWQMPFGGHQQIAHS
                     HIVSHFPFLHLLPRTLYRWILRLCGEQERVITELLDIKSTGCTIELFNRIARQANYQII
                     DRRLYLINPHYKIKFGLSPRRLNGVIAAIPYIRNFFCTSCFYILKKGTKTVNHY"
     CDS             complement(10584..12173)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 65.8;
                     E-value: 6.6e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg32_11"
                     /transl_table=11
                     /translation="MSLLYENYSEKMLKVCLRYIPDPTIAQDLLHDGFVIIFTSIHSLR
                     NPEKLEYWMKKIMRNLALQYLNHANANPTIPLTDIPEEEEPAENPFCPDFISYDKMLDI
                     VESLPEGYCKVFKLAVLEGLSHKEIGDLLGIAPHSSSSQLFRAKILLKKMLAGYRVFIV
                     LTVLLLFPTLYDYLYREKKSIRENRLSKVSSRQAGSTQQTKKADTPRTDEQCYTKENLN
                     KRERIIPPVPVSTEWPLAIPTMKDSIHKYPIPSPFTGQTITNRQMAFVFSPSLMPPTRK
                     KKSGKWKLMLAGSLGPQLAQNLYKLIATPHTDGISSDFPQQVSTWEEYYSYLHTRYQQG
                     TLGKDSIGLMQIAQNNSGRIVENQQHHAPIVVGLSLSKKLNERWSLETGLQYTLLRSEF
                     TTGEAFRIQDNQKLHYIGIPLRLSYRFWHYKRFSSYATAGMQVDIPIKGTLQSFHVTDS
                     IPHKLDSQPVSAPWQWSVNTSIGIQYRLTPQAGIYLEPTVNYYIPDGSQLRTIRKEHPF
                     TFTLPVGLRISW"
ORIGIN
        1 ttaaaaaatt aagtttgaat tatccaaaaa aaaatgctta ctttgcagac caaatcagat
       61 ttttggagaa attgattatt aacgctaaat caaaataaca aaatgtattt attattagtt
      121 atcttaatgc tgattgcatc tgtgctgatg tgcttcattg tattgattca aaattctaaa
      181 ggaggtggtc tggcatcagg cttttcatca tccaaccaaa ttatgggtgt gcgcaagact
      241 acggactttt tggaaaaagc aacctggact ctggcagctg tcatggtagt cttcagtatt
      301 gtttctgctt acactattcc ttcttccaca ggcaagggcg gtgatgtgat tctggaacag
      361 gcgcaacaag aagaaaaaac taatccttat aacatgcccg taggtacaga agctccgcaa
      421 tcggaggccc ctgcagctac aactccggct gaaactcctg ctcctgcagc agaagcccct
      481 gcagcagaat aagataagga tattgcggat gactcccgct tggaaaaata agagaaaggt
      541 tgatactgaa aaggtgtcag ccttttttcg ttttgatgaa gtatttattt acctttgtca
      601 gcaatttatg caatctgatt aataaattga aatccaaata gtacaatgac agaacaactc
      661 aaacttaaat tgaatgattc caaggctacc cgttgggggg cattggtgat tgttgccttc
      721 acgatgatgg cagcttatta tgtaaacgac gtggtagcac cgttgaagac aatgttggaa
      781 acggacttgg cttggtcgag taccgatttc ggattcttta ccggtggtta tagttttctg
      841 aatgtttttt tcctgatgtt gatttgggga ggattaatcc tcgaccgctt tggtatccgt
      901 ttcaccggaa agctggcaac tatcctgatg gtaggtggta cagcacttga atactatgca
      961 atgacgggac ttgccggtgc cgacgcgact ttattcggaa tcaatgaaat atttggctat
     1021 aaaacgggtg tgtttgttgc ttttgccggt tattccattt ttggagtagg agcggaggtc
     1081 gccggtatta cagtttccaa aatcatagcc aagtggttta aggggaaaga gcttgccacg
     1141 gctatggggg tacaagtcgc tttagcacgt atcggttcgc aagccggtta tgccgtagcc
     1201 attcctttgg cccgcgcttt cggtatttcc acaccggtgt tgttgggttt ggttctgttg
     1261 ttgggcggta tgattgcttt cttcgtcttt gcagtgatgg acaagaagct ggacaaacag
     1321 atggaagctg ctgccattgc tgccggtacg gaagatgagg aagagaagtt ctcttttaag
     1381 gatgtgaaga atattctggt caatcccggt ttctggctga tagcattgct gtgtgtattg
     1441 ttctactctt gtgtattccc attccagaag tttgcttccg agttgatgat tatcaaatac
     1501 ggtatcaatg agaatgtggc cggtacattt gccggacttc cggcattggg agcgctgatt
     1561 ctgactccgg tctttggtgg tttcattgac aagcggggca agtccgcatc tatcatgctg
     1621 ctgggctcgg ccatgctgat atgtgtgcat ttcatttatg ctattcccga tataaactat
     1681 tggctggtag ctattgtgct gatgataatt ttgggtatcg ctttctcgct ggtaccttct
     1741 gccatgtggc cggctgtggc caagatattc ccggtaagcc agttgggtac ggcatacgca
     1801 ttgattttct ttatccagaa tatcggtctt tggggtattc ctacattgat agggtgggtg
     1861 cttgatgcct attgtatatc cggcaagaaa ccagatggaa cgaatatgta tgactatacg
     1921 gtgcctatgt gcatttttac cggtattgcc tgcttgtccc ttatagtggc tctactgctg
     1981 aagaaggcag acaagaagta tggttataag ctggaagagc ctaatattca gaaataatag
     2041 gaaaagcgga taccgtatga tggaaatacc cgaaggaaaa gtaagtctgt tggacgctgt
     2101 tccggtccgc tgtggacata taacaaccga atgggaaggt gagtgcgccg tactcgccta
     2161 cccacggttt aaatacgaat ggatgcgtcg ttttttattg ccgaagggga tgtctcctga
     2221 catccatgtg aggctggaag aacacggtac agctgtctgg aatctgatag atggacatcg
     2281 taccgtgcgc gaaatcatct ctctacttgc caggcacttt ggggaggaag agaattatat
     2341 tccccgggtc accgcctacg taatgcagtt gcgtaaggat ggatttatcc agttgacaat
     2401 ccggaattag aattccttta ttccctatcc acttttatca atcctcccgt tgccgtatca
     2461 aacagcactt tgatggtaga attcttgttg aacagtaccg gtgcgaggta ttctacggtg
     2521 ccgaattggg taatgggaag ttggtcgtca aacaatttct tattgttata catcaatgtc
     2581 acttgtgcct tgcccggaag gttataggct acaccgtcca ctttcttttt gccttcctcg
     2641 gtggcagata catcgggact tttgaggtcg gtgacgctga tataatacgg ttcaccggca
     2701 aggtcattat tggccaccac tcccagcttt cgggaaaaac ggaaagccac ctcatctttc
     2761 atctctttag gcgtcagccg gatggtgaat gtcttgggtt ctttctttat tttgcccgag
     2821 aacatttccg tcatagccgt ttcctgctgg ttcagattgt caagcatcag cttgagttgg
     2881 gcgccgtcct tgggcatatt gtctgcttcg ccgcgcagga gggcattctt gctttcgcgg
     2941 atgctgtata tttccttagc caccagctcg gccatcttgg cactggagtt ggacatcagt
     3001 atttcttccg tcagaaaact gcgtgggtca atgctgcttt cggtggcttt ggcttcgggc
     3061 gtcttggcag caggcttacc gctgaacgga atgttgatgg agcggacaat tccgtcttcg
     3121 gtaagctcca taaggggtgc tacggtcttg tctttcatct tcacgaaata gacgttgtcc
     3181 ttatccggta caccggctat gcgggtttct atcttatcca gtgtccagaa ctcctcgggt
     3241 tcggcagaca cgttgttgag acgcagatag cggtcggcat atctgcaaaa ttctccggga
     3301 gtgtaggtat gcttggtggc ttgcaatacg atttctattt ctgttttggg taacatataa
     3361 gtcactccgt agtctttgcc acgcatcaca ccggtggtta cgtctgtttg cgccatggca
     3421 gtgatagaca agaacagagc tgagagcatc aatatattct tcttcataat gtacattcgt
     3481 ttagactgat ttagctaagg gacaaagtta atgaagttat ctttgctaaa tattgcttta
     3541 taaattatta acagagctga cgaactgtac gcaaaccggc atgtcgacta caatgtcctg
     3601 atgagtatct tccaagagtc cggtaacttc gtttcgtttg tatacctgaa tgacattgct
     3661 gtcgcggcag gcggcaagca agtatttacc gttgggcgtg atgttgaagt tgcggggatg
     3721 gatgccggtg ggctgataac ctacctttgc caaggtccca ttttcgggat tcacggcaaa
     3781 gatggcgatg ccgtcttctt tcagacggtt gctggcgtag aggtatttcc catccggact
     3841 gaggtggatg tctgcacttc cacgggcggc tacggtgtcg gctgtgatag tctgtatctg
     3901 ttccaggcag ccgtcgtcgt aactgaaggc aatgacctta ccggacagtt cggtgatgag
     3961 ataggcaaac ttcccgttag ggctgaatgt cagatggcgc gggccggaat ctgcctcaat
     4021 gccaacggct tccagagaag catgaggaat agggttgtcg gggtgcatca caaagcgcag
     4081 gatgcggtcg gcactgaagt cggtggcgaa gatatacttt ccgtccggtg aaaagaccgt
     4141 gcaatggatg tggggagtgg cttgccgtat ggcgtcggga ccggtggcag agccttgaaa
     4201 gagcgtgtct gcaggagcca aagtgccgtc tttctgtaaa ggaaagacgg acatggttcc
     4261 accgctgtag ttggcagtca acacttcccg gccattggtg gccacgtagc aggggtcggc
     4321 gccgaaggtg ggaacggtgt tcagcaggcg cagttctccc gtttcccggt cgaaggcaag
     4381 ggagctgagg gctgctgtgc tgtcgttcat ttcactgacg gcatagacaa attcgccatc
     4441 ttccgagggg acgaggtagg agggattggg caatgccgct gaactgagcg gaacggctgt
     4501 tcccgtctcc tgattaaagc ggaaggtata gatacccttg cttgagccat tcgtgtaagt
     4561 acctattagc atggcgagtt cgtcctggtc accgttagtg ccctttggag aagagccaca
     4621 tgctgtcaaa cctaatccga gcatacagaa aagaagtgtt ttcattaatt taatgtgtta
     4681 atgtgccaat atgctaatgt gctaattggc tgcgctgtat atgctgcatg gtcattggta
     4741 cattagcata ttggcacatt agcacattaa aatttaactt cggcaatact gacgcggtca
     4801 tcgttcagca cgatgcggag gtcgctggcg gtagtgcctt tgaacggata ggaaatcagt
     4861 ttgccgtatt cgctgacggt gcccgaatat acggtgagga actgtccgcc accgcccgag
     4921 agctggattt cgaaggttgc cggcaggttg ttgtcacgtg taaaggcaat ggcaacttta
     4981 tctaccttgg ctccgttctt taaggcaaag gtaatataat ctcccttatt tccttgccat
     5041 gcggtattga ttttttcgtc gagcacgttt tcggcatcct ctgggttggt gctggcactc
     5101 acacgctttg ctggtttttg ggcttcaatg gctttggcac gggtctggta gtcttctacg
     5161 gtcagcgttc cgttcaggcg gatgtcttcg gaagaggcgc cggccatgag cacgaagtcg
     5221 ccgggttcca ccacccattt catgtcagcg tccagaagct ccaggtgctt gcggtcgatg
     5281 gtgaaggaca gctcctgggc ttcgcccggt tcgaggtgga tgcgctggaa gcctgcaaga
     5341 ttcttttcgt aggtggtgat gctgctcagt acgtcgcgga tatagagctg cactacttca
     5401 tctccggcac gtttgccggt gttggtcacc ttcaggcgga cggtggcaga ctcgttcggg
     5461 gtgatgactc ggggggtgat gtcgaggtcg gagtactcga aggtggtgta gctcaagccg
     5521 taaccgaagg ggtagagtgc tccgttgatg cgtgacatgt tgcccgtagg tcccggattc
     5581 ttaccgccgt ctatctgtga agaaggtttg caggggaagt tgaaggggat ttgccctacg
     5641 gtcttgggga aggtcaccgt cagctttcca ccggggttgt agtcgccgaa gaggatgtcg
     5701 gccagggctg ttccgccttt ggagccggga taccaggctt cgaggatagc ggggacgaac
     5761 ttgtctgccc agttgatgga gagcgggcgt ccgttgatga gtatcagtac gacgggcttg
     5821 cccgtggctt gtatggcttg aagcagttgc aactgccgac cgggcaggtc gaggctggtg
     5881 cgcgatttgt tttcgccgca ggtgcgttgt ccgccgccca atactacgat ggcaacatca
     5941 gcttgacggg cattttctac ggctttgtct atctcggctt gttcgtcgtc ggtcagcgga
     6001 tagtctatga tttcactttc gggccagtgg gcgtccacca ggtcgcagcc tttggtgtag
     6061 agcacctctg ccttgccttt tgtcttttct tgaatgcctt ccagcacagt ggtcacttct
     6121 acggcaagtg ggccgtaatg ggtcagcgcg tagccttctt cattggcatt gggaccacag
     6181 acggcaatct tcttggtgga gttgatgtct aagggcaata gttcaccggc attcttcagc
     6241 agaacgatgg actcgcggga tgcctgcaag gcaatggctt cgttctcttc tttttccact
     6301 tcacggtcgg catcggcaag gtctgtctga tagggggcat cgaacagacc gatgaggaac
     6361 tttacccgaa ggatgtcgcg cacgcggtcg ttgatgactt cttcgctcag tccgccttcc
     6421 ttcaccagtt cgcggagggg aaggacgaag gagtcgggcg agcggaaggt gcagcgtacg
     6481 ttcagtccgg cttccacgct ttggcggacg gcttctttca tgtctttggc ggtgccgtgc
     6541 ttggtgtaga ggtattctac ggcgtcactg tcggatacga cgtagccacg gaatcccatt
     6601 tcgccacgca ggcgggtggt gagccagtag tagctgccct gcacggggat gccgtcgtaa
     6661 tcgttgtacg aactcattac gcccagcatg ccagcttccc ggatgacgcg tttgaagggg
     6721 tagatgtgta tgttttccac ttcgcgcggc gacatttgcg ggtccacgcg tgccatgcct
     6781 tcgcgggcgc ctttgttgtt actgtaagcg gcaaagtgct tgccggtggc ggccacttgg
     6841 tggttgtgct gcaagccgcg caccatttcg atgcccagtt cggctacgag gtagggagat
     6901 tcgccgtaaa cttcttcgta gcgtccccag cgctggtcgc gtcctacgtc gaggatgggg
     6961 gcgtagacgt tggtgtagcc cagcatgcgg gcttcgcgtc cggtgatgag tcctacttgg
     7021 cgaatcagtt cacggttcca ggtatgtccc agtcccagtt gggtggggaa gttggtggcg
     7081 cggtagcttt ccacgccgcg tatgccttcg ttggtaaagt ctacggggat gccgagacgg
     7141 gtatcttcca caaagaaccg ttgcacctcg ttcagtgccc aggcgtggcg cgaggcgggc
     7201 cagacgtagg cattgtccga gggaggcagc ccccattgct ggaagccgtt caggtgttcg
     7261 tcgatggcgc cgataccgtc tttccagagc agctctttcc attcgggggt ggggaggtcg
     7321 tctttcagta cgcgtttgta gccgtagagg gtgaccattt ggcaggtctt ttcgtccagc
     7381 gtcatctgtt gcagcaggtt ttcgatgcgt gcttcgagcg gggcggaggg gtcttcgtac
     7441 acgtctttca ctccgttttt gttgaagtct atccaacctt tgcggtacat ttcacttttc
     7501 accggcttgt aggttgccgg tgttttggca ggcttttgtg cgcagagcag tgtgcttcct
     7561 ccaagcagca gggttagggc aataaggttc ttcatgatat gttctaaaaa tctcttggtt
     7621 attattgttt cttttgttga caaaaatacg gctaatgtgt gaaataaagg gataaaatag
     7681 tccgaagtat cggcttttat tgtccgaagg gtcttcctct tactaaaaat atcctccaag
     7741 acgctaccgg ggaattcaaa tcattattag acgaaacata tcattcactt ttaaaaagaa
     7801 agagagaaca ctataataac ctgaaaagta gatgcaatcg cggtgtatac aagtattacg
     7861 gctacatctg ttaaacgagg gtgtatttat ataataggaa tctgttggcg gaattgttgc
     7921 ttgtacggaa gaactttctt ttcaaccttg ggatgtctaa acccaacctt ggtttagaca
     7981 tcccaaggtt gggtatggaa aaaccaaagt ttgggataga ttgcttcctt aattctttcc
     8041 ggtttttcag ttaacttcag agactttttc cgttaacttc ccatctcttt tgtgcaaata
     8101 tccattacag aagatagata ttccctcttg cagggggtaa ttccgtcaac ggatactggc
     8161 tttggtagct gtttgaacat tgatgacaat ggggtgcaca tattctatgt atggaagatt
     8221 attgttttta tcacgaaaag tcagtattag ctaatatttg taaatatatg gtgattgcta
     8281 ataaaagaat atgtatcttt gggccaaaga aagcggtaga ggatgaaaaa taaagtagca
     8341 tttatccctt tttcaccctc cctacttagc aatgagttac gcaatctttt aaatttcaga
     8401 ccgttacaaa gtcatggggt tgactggatt tgacagcggg cagaaatggt aagtaagcat
     8461 gcagtgcgtc gttgatttgc actttaatct cagtcctcaa aattttatct ggcgaaactc
     8521 gttacgctct cgctgcttaa tcgaagtata gtagattgaa gcttaatccc ggcaccaggt
     8581 gctgggacgt gacatcactc ggaagctgtt gctccgaagc attccgataa agtggtgcag
     8641 tcaaatcggg gatagttcgt gtcagcctcg tggcgcgggt gaaaatttag aggataaggc
     8701 aacggttgat ggctttggtt ctgccgctgc acgaaaattt aggcaaagat aagcatgtag
     8761 aaagcttatg atttcctcgt ttggacgagg gttcgattcc ctccagctcc acggaaatag
     8821 taaaaagaag tttgtaagtc cttgaattcc agtaattcag gggctttttc ttttcttcta
     8881 ctccccctac cttttatatt catttagaaa acagttgtag taaatgtgct acaattcaaa
     8941 attaatatct acttttgtct gttcaaaaac caataactat tagaagtggg ggcaacactt
     9001 taaattctgc aacagattta tgaaaattca cgaaggaaaa tgtacagaga agattttgaa
     9061 agaacgtgaa cggattggta accggttagc cattcttcgc aagaagagaa atatgaccca
     9121 agaggaattg gctaatcttt gtggcgttaa tcgtgttaat atagccaaga tagagaaagg
     9181 ggcttataat gtgagcattg atatactatc taaggtaaca tccgctcttg gttttgtgat
     9241 agatataaaa gtggatagct ctgtttgtcc gactcatttc tctcaacgta aacctgtaaa
     9301 gctggtaata ggggaagatt attatgtcag ttttggcaat aacgaagccc atagatgtaa
     9361 gctggtggat attccggaga tgtaccaagg tcaaagaatt aaaatcgaaa ctccgacccc
     9421 gagagggtct atcacccaca tattatttgc cgatgaaata ggaacgacac ctgacgaggc
     9481 tgtaatgaac caagtaacga tgtaaaaaca ttaaaaggga ggaagtgcaa gttccccttt
     9541 tattgaaatc accttcgcta caaccatctg cagcgagggt gattttttag tttatgaggg
     9601 tttctacacc ccctctttca tcagggctat tcagaaattt aatggtttct tctgaatata
     9661 taatcttaaa ttgatggttc ggaatcaatt ctaaagctgg gaaatcagta gtgattaaca
     9721 gttttagtcc ctttctttaa tatgtaaaag caacttgtac aaaagaagtt tcttatgtac
     9781 gggatagcag caataactcc gttgagcctt cgtggggaca agccgaattt gattttataa
     9841 tgtgggttta taaggtacag tctccggtca atgatttgat agttggcttg ccgggcgatg
     9901 cgattgaaca gttcgatggt gcatccggtg ctctttatat ccagtagctc cgtgattacg
     9961 cgttcctgct caccgcatag tcttaatatc catctgtata aagtgcgggg aaggaggtgg
    10021 agaaaaggga aatgtgaaac aatgtggctg tgtgctatct gctggtggcc tccgaatggc
    10081 atttgccagg cgggaaatcc tacaaatata gctccgtcgg cagacaaatg tttttgtagg
    10141 ccggagagga accgttcttt gtctctgata tgctctatca catcgtgtag aagaattagg
    10201 ggaaaattcg tagccttgtc cttaagctgg aaaatgtcgg tggcaatgaa ctgtccctgc
    10261 tgatgccttt gggcgaagaa ggttctggct tgttctattc gcgtggcatc aatgtctacg
    10321 cccatcaccc ggcaaccggc ttcggcaaag gggagcagat tgcctccctc tccacagccc
    10381 acttccagca ctttatcggg gatgtgtccg atgacttcct ttatgtaggg gatataatag
    10441 ttcttgctgg tctgtgactg ttcaccaaag tagctttccc ggtcggtatg tcgtttctgc
    10501 atgttctttg ttccttcttg agtttgatta tccatataaa tagataatca gtcgggtaaa
    10561 agactgcgtg gcacatcgtt tttttaccag gaaatgcgga ggcctaccgg gagggtgaat
    10621 gtgaacggat gttcctttcg gatggtgcgc agttggctgc cgtcggggat ataatagttt
    10681 acagtcggct ccagatagat gcctgcctgg ggtgtgaggc gatattgtat gcctatactt
    10741 gtgttgaccg accactgcca gggagcactt accggctggc tgtcgagctt gtgtggaata
    10801 ctgtccgtga catggaagct ttggagtgtc ccttttatgg ggatatccac ctgcatgcct
    10861 gccgtggcat aactggagaa acgtttgtaa tgccagaaac ggtaggaaag ccggagagga
    10921 atgccgatat aatgcaactt ctggttgtct tgaatgcgga atgcttcgcc ggtagtgaac
    10981 tccgacctga gaagcgtata ttgcaatccg gtttccagac tccaacgctc attcaatttc
    11041 ttgctgagag agagtcccac gacgatgggg gcatgatgtt gctggttctc aacaatcctg
    11101 ccgctgttat tctgggcaat ctgcatgagt ccgatggaat cttttcccag agtaccctgc
    11161 tgatagcggg tgtgcagata agaataatac tcttcccacg tgctgacttg ttgagggaag
    11221 tcacttgaaa tgccgtcggt atgtggagtg gcaatcagct tatataagtt ctgtgccagt
    11281 tgcggtccga gtgaacctgc cagcatcaac ttccattttc cggatttctt cttgcgggtt
    11341 ggcggcatca gggaagggga gaagacgaaa gccatctgtc ggttggtgat ggtctgtccg
    11401 gtgaatggag aaggtatggg atatttgtgg atactatctt tcattgtggg tatggcaagg
    11461 ggccattctg tggaaactgg aacgggaggg atgattcgtt cccttttgtt cagattttct
    11521 ttggtatagc attgttcgtc ggttcgggga gtatcggctt tctttgtttg ttgcgtactc
    11581 ccggcttgcc tggaagaaac tttggacaaa cggttttccc tgatactctt tttctctctg
    11641 tacagatagt catatagcgt tggaaagaga agcaatactg tcaaaacaat gaatacacgg
    11701 tatcctgcca gcatcttttt aagtaaaatt ttcgcccgga acaattggga ggaagaggag
    11761 tgtggcgcta tacccagtaa atctccgatt tctttgtggg acaatccttc cagtactgcc
    11821 agtttaaata ccttgcagta gccctccgga aggctctcca ctatatccag catcttatcg
    11881 tacgaaatga aatccggaca aaaaggattt tcagcaggct cttcctcttc cggaatatct
    11941 gtcaatggga tggtggggtt ggcattggca tggttgaggt attgcagtgc caggtttctc
    12001 ataatctttt tcatccagta ttccagtttc tccgggttgc gcagcgaatg aatggaagtg
    12061 aatatgatga caaaaccgtc gtgaagaaga tcttgggcta tcgttgggtc gggaatatag
    12121 cgtaggcata ctttcagcat tttctctgaa tagttttcgt agagcaggct caaggcctgc
    12181 ccgtttccct tctggcataa agtgacaaga gcttttgtat ccatgtgttt gtctcaatgt
    12241 tatttcttaa ggatagagaa gaacatgaat gactgcatgg atttttattt tttaactaag
    12301 cctcccggtt gacttctgct gcacagtccg gacaaatgcc tttcagtaca tagttgatgc
    12361 tgttcagtgt aaatccttga ggcagcttca ccaccggagt gggaatgttg
//
