LOCUS       c00019_gnlPro..        13620 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BNKKIHOE_19.
ACCESSION   c00019_gnlPro..
VERSION     c00019_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:05:24
            Original ID  :: gnl|Prokka|BNKKIHOE_19
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13620
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13620
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[41:3620](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(42..3620)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13620
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13620
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(42..3620)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_1"
                     /sec_met_domain="PFOR_II (E-value: 3.3e-18, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.5e-79, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 9.4e-33, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 6e-14, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.5e-11, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.1e-06, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.7e-26, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLALADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATTGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGSDKPAE"
     CDS             3966..5447
                     /locus_tag="ctg19_2"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLRRPWKRADYQDLIRGVAGEDWFDIS
                     PEARRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             5465..6250
                     /locus_tag="ctg19_3"
                     /transl_table=11
                     /translation="MAPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAAVFAESGIEDIPERLTAALHAANRALAAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADCLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGIIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             6503..7147
                     /locus_tag="ctg19_4"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLVVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTEHSFYSKKSK"
     CDS             7152..8159
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_5"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 1.4e-43,
                     bitscore: 138.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLHKIAVIGAGSWGTALSMVLATRECEVVLWTPEEAQARQLAE
                     TRRSPVLSKTALPLAPNIHPTCDLGQVKDAELIVVVVPSVAMRSVAQRLRSLPVQPDAV
                     IVSCTKGIEQGTHKRMTEILQEYLPSNPIGVLSGPNHAEDICLGLPSASLIGFEDPKYA
                     DWVQQIFASKTFRVYSATDIIGMQLGGTIKNVFAIGAGLCEGLNLGDNAQAALLTRGLA
                     EMTRIGVASGGRRETFMGLSGVGDLIVTCYSRHSRNQTVGRRLAEGKSLQEILDTLGMV
                     AEGVPNTLSVYEIARELDVRTPLIDAVYSVLYESKPPMEALAELMTRDPRPESD"
     CDS             8217..8651
                     /locus_tag="ctg19_6"
                     /transl_table=11
                     /translation="MKRAIISALFAAGVLGVASADIQAPPASEYTPTRKLGRAIANLIY
                     SVEEIPLGIINWTSREGDYAGFSVGIVDGTATMFERMGYGIYELVTFWAPTYKCTYKPP
                     YQGRCGMSGLKEYNPNGGLSEFPAELGFQSYYKYSRQQRD"
     CDS             8793..9611
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="MNKTAAFIGLGAAVCITAPSFAQDSHLSLTRQSVASMHEITAALD
                     KVTDEPGAAAAVETVKKVRKKLLDLGKRQLELPGATLQEQAQVSAQMTEVQKISDELVK
                     SLARLKKEGLLTPDLQKALADLRSVQTELAQASRDKAEQAEPFPEDAEGNTHETLLVKT
                     VDEVKKLDDSLAKVRDEETGKAAVEQIGRYRAALLDVARKQAALPPLTRNQQAKLMGVQ
                     QQLVEMMQPIVKHVTAIMLSPDASKNLKEAVNSLSELPKEVQKIREEAAK"
     CDS             9683..10744
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_8"
                     /sec_met_domain="Radical_SAM (E-value: 4.6e-24, bitscore:
                     75.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPVFSETDLNERPFLVFWEVTRACALACRHCRAVAQPRPHPDEL
                     THEEALRLIDQLAELRPPMLVLTGGDPVMRPDILELVRAASGKGLHVALSPAATARLLH
                     TDFRALKEAGVQSMSLSLDGAHESTHDAFRGVPHTYERTLRAAEMAKEAGMHLQINTTI
                     TKSTLGEFDDFVELMKRMKPGMWSVFLLVPTGRAAMDEMPAAEEVEAIWKKLSRISHEV
                     SFGVKTTEGHHYRRVALQEARAQGSKPARRAIPTRDGKGIMFISHTGEIQPSGFLPMTA
                     GNVRTDDPGEIYRTHPLFLKLRDDNALQGKCGRCEYRTICGGSRSRAYAVYGDMMAEDN
                     LCPYQPRLSQHHD"
     CDS             10737..11984
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_9"
                     /sec_met_domain="Radical_SAM (E-value: 4.1e-28, bitscore:
                     88.3, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINITRLWTGAEQPADHLRYGQGHGHGRFAGGAAESCAPASSRMR
                     KPIVVWNITRTCNLKCVHCYADASARKFKGELDWEQCCAVIDDLADYKVNALLFSGGEP
                     LVHPRFMELLERATGKGLKVTISTNGTRITPEAAARFKELGVAYVGISLDGIGAVHDKF
                     RGVEGSFEQAVRGFRLCSEVGQKTGLRLTLTRNNVQCMGQILDFIDANDIQRVCFYHLV
                     PTGRGVEVQTLTQEEARNAMDTLIARVEEWKAEGKNREVLTVTQPADGIYLLLRQLREG
                     SPLAKETLGLLQWNGGGANSSGRGIANIDTQGAVHPDQFWQSVTLGNVKSDRFSDLWDA
                     RAGAAVEMLPELRGSDDPLERQKKIEGRCGRCAHFALCGGGFRTRAAFAHGHWYGSDPG
                     CYLTEEEISTPLPEIR"
     CDS             12235..13536
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_10"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 3.6e-136,
                     bitscore: 443.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRMMSQELRPETLCVQAGWAPKKGEPRVLPIYQSTTFKYETSEQ
                     MAKLFDLEEAGFFYTRLQNPTNEAVARKIAELEGGVAAILTSSGQAASFFAVFNICEAG
                     DHIVSAAAIYGGTYNLFAVTFRKMGIEVTFVDQDAPPEEISKAFRPNTKAFFAETISNP
                     TLCVLDIRKMADIAHAHGVPLIVDNTFATPINCRPFEWGADIVTHSTTKYMDGHAAAVG
                     GVIVDSGNFDWEAHKDQFPGLTEPDPSYHGLSYSKSFGKGAYITKATVQLMRDLGSIQS
                     PQNAFLLNLGLETLHLRVPRHCENAQKVAEFLQGQEDVAWINYPGLSSNEYYELAQKQF
                     RGGQSCGVVTFGIKGGRERSIKFMDSLKLAAIVTHVADSRTCVLHPASHTHRQLTDEQL
                     MEAGVRPDLIRFSVGTEAAEDIIADLKQALEAIR"
ORIGIN
        1 gataagccgg acaggggcgt tgaaattaag cggcctgtac cttattccgc aggtttgtcg
       61 gaacccatgc cggcaatgct ttggtacagg ttccagcggt gccagacatc cttctgggct
      121 tcttcaagga gtttttcgaa tccttcctta ttggtcttcg ccagaagctt gaagcggttt
      181 tcgctgagca gcacatcgcg cagatcgcct ttcgggcctt tgccttccac aatcagcgga
      241 ttcttgccct ggcgggccag gtccggatta tagcggtaaa gcaggactcg gccggaatcc
      301 acccatgcct tctgctgctg caggcccttg gccatattga tgccgtggga gatgcagtgg
      361 gagtaggcga tgatgagagc cgggccgtca taggcttccg cttccacaaa ggctttcagc
      421 gtgtgttcgt ccttggcgcc gagagcgacg gaggccacgt acacgttgcc gtaagtcatg
      481 gccatgaggc ccagatcctt tttcactccg ggcttgccgg tcgtggcgaa tttggctact
      541 gcggcgcgcg gggtggattt ggagcactgg ccgccggtgt tggagtatac ttccgtatcc
      601 atgaccagca ccttcacgtt ccggccgctg gccagaatgt ggtccaggcc gccgtagccg
      661 atgtcgtagg cccagccgtc gccgcccaga atccacacgc tcttgcggac aagtttatcc
      721 gcaagggcca ggaggcgcgc gtattccggc ttgccggcga ttttcttctt gagttcttca
      781 atgttttcac gctgctgggc gatgtctgct tcatccttct gcggattagc cagtatccga
      841 tccaccagtt cctggcccac ggcaccggca gcttcatgaa gaagctcaat ggcgtgttcc
      901 atctgcttgt ccagggagac gcggaagcca agaccgaatt cggcgttgtc ttcaaacagg
      961 gagttggccc aggcggggcc gcgcccttca gagtcatggg accacggggt ggtgggcagg
     1021 ttgccgccgt aaatggagga gcagcccgta gcattggcga ccaccaggcg gttgccgaag
     1081 agctgggaga gcatttttac atacggggtt tcaccgcagc cggcacaggc gccggagaat
     1141 tcgaacagcg ggcgcagcac ctgcatggag cggatgttgt ccgttcttac cttggtgcgg
     1201 tccacgtccg gaaggctcag gaagaaattc caattggctt cttccttgtc gtgaatcttc
     1261 ccggccggga ccatggtcag ggccttgtgc gtcgggtccg tcttgctctt ggccgggcag
     1321 acgtccgcgc agagcgtaca gcccgtacag tcgttcgggg aaatctggat gacgaatttc
     1381 tctcccttcc agtccggatg cttggcatcc aggcattcaa acccttccgg agcgtttgca
     1441 agagcatcag gagagaagaa tttgctacgg ataaccgcgt gcgggcagac ggcggtacac
     1501 ttgccgcact ggatgcagag ggtcggatcc cattccggca gatccagggc cagattgcgt
     1561 ttttcgtact gggacgttcc gttcgggaat gtgccgtcca cgggcatttg gctgaccggg
     1621 atgctgtcgc cttcaccgca catcatcttg ccaaggacgt tttgtacgta gtccggagcg
     1681 tccggggaca tggcgggcgg aatggcgtgt ccgtttacag tttttccggt tgtgtccacc
     1741 tggtgcaggt tttccagcgt ggcgtccacg gcggcgatgt ttttgtccac cacttcctgg
     1801 cccttcttgg cgtaggtttt ggcaatggcc ttcttgatgt agccgatggc ttcatccgcg
     1861 ggaatcacgc tggccagctt gaagaagcag gtctgcataa tcatattgat gcggccgccc
     1921 atgcccgttt tgcgggccac ggcaaaagcg tcaatcgtgt agagcttgat gttcttgtcc
     1981 agaatctgct gctgcatgcg ggcgggcagc gtgtcccaga gcttgtccgc cgggtgcggg
     2041 ctgttcatca ggaaagtggc gccgttggcg gcattcttca ggaagtcgaa caaatccagc
     2101 agggaaggct ggtgcagggc caggaagttt gccttggtga tcaggtatgt ggatttgatc
     2161 ggacggggac cgaagcgcag gtgggaaatg gtggaggacc ccgatttctt ggagtcatac
     2221 acgaagtagc cctgcacata caggttcgta tgctggccga tgatcttgat ggcatcctta
     2281 ttggcgccca cggtgccgtc ggagccgagg ccgaagaaca tggcccgcgt cacgtcgtcc
     2341 gcttccgtgg aataatcttc atcatacggg aggctggtgc ccagtacgtc gtcgttaatg
     2401 ccgatggtga aatgattctt gggagtgtcc agagccaggt tgtcatagac gcccttgacc
     2461 atggcggggg tgaattcctt ggaggagagg ccgtagcgtc cgcctaccac cttgggcatg
     2521 ccgttggtga agggcagcgt gccgttggcc tgggcgtcga agagggcctg gatgatgtcc
     2581 tggtggagcg gttctccttg ggagccgggt tccttggtgc ggtccagcac ggcgattttc
     2641 ctgaccgtag cgggtagggc cttgacgagt tcggcggcgg ggaatgggcg gaacaggcgc
     2701 accttcagca cgcctacctt ggcgttttcc cgggtcatca tggcttctac cgtttcttcc
     2761 acagcttcag cgccggatcc catcaggata atgacgcgtt cggcgtccgg agcgccggtg
     2821 taatccacca gatggtagga acggccggta agttccgcga atttgtccat ggcgttctgg
     2881 acaatagccg gagtggcttc atagaaacgg ttgaccgttt cacgtccctg gaagtaaacg
     2941 tccgggttct gggcagtgcc gcgcagaacg ggagcatcag gagtcagggc tcgttcccgg
     3001 aaggaatcca gccattcctg cttaatcatg ccgttcaggg tatcgtccgt gatgtctgca
     3061 atcttgccga tttcgtggga cgtgcggaac ccgtcaaaga aattgatgaa aggaatgcgg
     3121 gattccagtg tagcggcgtg ggaaatagcg gcgaagtccg cagcttcctg agtggaggag
     3181 ccgcacagca tggcccatcc gcaggagcgg gcgctcatca cgtcgctgtg gtcgccaaaa
     3241 atggaaaggg cctggtaagc cagggaccgg gcggctacgt ggaacacggc gggagtcagt
     3301 tcccctgcga ttttgaacat gttcgggatc atcagcagga gcccctggga tgcggtgaac
     3361 gtagttgcaa gcgctccggt ctggagggcg ccgtgaacgg tgcctgccgc gccgccttca
     3421 ctctgcattt ccactacgga gggaacggtg ccccacaggt tcttcctgtt gacagcggcc
     3481 cagctttcag ctgattcacc catcggagaa gatggtgtaa tggggtaaat ggcaatgact
     3541 tcagaaaaac gataggctac ggaggctacg gcttcgttag cgtcaatcgt gctgtaagtt
     3601 acggttgtct gatcactcat aagtctgcac ggatagtata taattgataa ataaggtgcg
     3661 tcttaacggg aacatttata acatgtctgg tgccaaaggt aaaagcaatt atgcgtatgt
     3721 ggggatttgc cggccatttt ttaataataa gaccagtttt gtttcaattc ctttgaatat
     3781 cgtgctttat gtggttctgt ccaggctttt tgcaaaatgg ccggaatact ggggcatgtt
     3841 ccggcgtccg gcttccgaaa aagggggggg aggaaccttc gggtcaaaac cggccgccaa
     3901 aaatgtcccc tctgcctgac aatgcgctag ccaaaacgga agcaagcctt tagaatcccc
     3961 gcactatgtc cgaacaacag caggcacatc cgactacgac ggaatccgaa cttattgccg
     4021 tgcgccgcga caagctcgcc aaaatccgtg agctgggaat tgacccctac ggcgcaagat
     4081 ttgacgtgac caccactccc gccggattga aagccgattt ccaggaagac aaacaggtag
     4141 ccgtcgccgg ccgccttctg gctattcgcg acatgggcaa atcccagttt ttcgtcattg
     4201 gggacgtacg gggaaaaatc caggggttcc tgcataaaaa tgaggtggat gaaaccacct
     4261 ggaagctttg gaagctcctg gaccgcgggg actgggtcgg catcagggga accacgttcc
     4321 tgacccgtac cggagaacct accgtaaagg tatccggact gaccattctt tccaaaagcc
     4381 tccgccccct gccggacaag tggcacgggc tggcggacaa ggaggtgacc taccgcaagc
     4441 gccacctgga cctcatttcc aatgaggaaa gcgcctccct gttcgtgacg cgctccctca
     4501 tgattgcgga aatccgccgc tttctccagg aacgcggtta tctggaagtg gaaaccccca
     4561 tgcttcagga tgtggccggt ggggccgccg ccaagccgtt tgaaacgtac cataacgcgc
     4621 tggatatgcc gctgacgctg cgcattgccc cggagctttt cctcaaacgc ctgatggtgg
     4681 gcggcttcac gaaaattttc gaactcaacc gcagcttccg caatgaagga attgaccgcc
     4741 gccacaaccc ggaattcacc atgctggaag cctattgcgc ctgcggtgat tttgaaacca
     4801 tggcgaatat ggtggaggag ctcatctgcc atctggcgga aaaattctgc ggcggccttc
     4861 agattgacca caaggacgct gaaggcaatg ttctttacac aatcgacctc cgccgtccct
     4921 ggaaacgcgc cgactaccag gacctgatcc ggggcgtggc aggggaagac tggtttgaca
     4981 tttcccccga agcgcgccgc gcccgctgtg aagagctggg agtggaaatc agcccggata
     5041 tgaaagatgt ggatgtttcc cagcaggtgt atgaaaaact ggtggaggaa aagaccatga
     5101 acccctgctt tgttacccac gtggccaagg acttggttcc cctggccaag ctgaaccggg
     5161 aaaatccgga cgtagtggat gtatatgaac tggtgatcaa cgggcaggaa atttcccccg
     5221 gctattcgga attgaacgat cctgacgtgc aaaaggaacg cctggagcac caggctgccg
     5281 gggagaccca gcgtgtggac tatgatttca ttgaaacgct ggaatacgga atgccctccg
     5341 caggcggcat cggcatcggc atcgaccgcg tcgtcatgat gctgacgggg gcctcttcca
     5401 tccgtgacgt gctgctcttc ccgcagttga aacgtaagga cagttaatcc gaaccaccgg
     5461 ccgcatggct ccccgcaccc cggatattct ggactgcgct tccgcccaat ggatcggcaa
     5521 acgccgcgag caggaagacg tggttaaaag tcttcccgcc gccggcggga tgctgggcat
     5581 cgtgtgcgac ggcatgggag ggcatcttcg cggagattgc gcctcctgtg tggtggcgca
     5641 ggaatttgct gcggtatttg cggaaagcgg catcgaggat atcccggaac gtttaacggc
     5701 ggctttgcat gctgccaaca gggcgttggc cgccattcag aaggaaccgg aggaatccgg
     5761 aaccacattg ctggccgtct tcatccgcga ccatttcctg tggtggatca gcgtgggaga
     5821 ctcccccctg tatttatgga gcggagcgga cagctttcgc atggaccgtc tgaatgaaga
     5881 ccattccatg agaccgattg cggattgcct ttaccggaag gggaaaatgt cacttcaggg
     5941 tgcgcttcgg cagcgttgca ttctccgttc cgccgttatg ggcggtccca tggaactggt
     6001 ggacatcagc gccatgcccc tgctcctgca tccgggagat gcggtgctgg catgctcgga
     6061 tggcttgcag gtttggagcg agctgttgag agaaccttct ttcctggctc ttcaaaaggc
     6121 cagggattgt tccagcaggg agctggtggg gatcattatg gaacaggtga aggatatgct
     6181 ggagccccag caggataatg cctccgtctg ggctgccgtc atgcggaaac cctgcgaggg
     6241 cggtaaataa gcttattccg gcgaaggaag tgcgggagca tggttctggg cgggcgggaa
     6301 aatgttcgcg ctgttcttat tgcgccttaa acagggcttt tccgcagacc ggggcacgga
     6361 gagccttgaa aatgaggatc tggaggaggc tgtcaggtat ggtgttcttt tacgggagca
     6421 acccctccgg aaagaaccgg gccggaggtg atttccccat tgtcatttga ccggcggggg
     6481 attaaaatgc actccgcaca acatgattgc ctggatagtt ttctattacc tgatcggagc
     6541 gattccgttc ggctaccttg ccggcagaat cagagggatt gacctgaggc agcagggttc
     6601 ccgcaacata ggcgctacca atgcgtggcg cgtactgggc tggaagtggg gcctttccgt
     6661 tttcattctg gacttcttaa aggggttcat ccctgtgttc ggcgccttga actggctgcc
     6721 gttcctgacg ggggatgcgg gcggctggga tttcaatgtc ttggtagttc tctcctgttt
     6781 cgctgttata ctcggtcata cttacacctg tttcctggga ttcaggggag gaaaaggcgt
     6841 agcgacaacc gcgggggttt tatttgccct caatccggtg gtggcttgcg tagctctggc
     6901 ttcttggctg gtggttatgg gaatctccgg catcgtgtcc ctggccagcc tggtggccgc
     6961 tgtggtgatg atcgccgccg gatggtggat ttatccgctt tgccaggacg gggatgtctc
     7021 cccccagata ctttacgtcg cctttttcac ggtggtaggc gcactggtga ttctcaagca
     7081 ccgttccaat atcgcaaggc ttctcaacgg aacggagcac tccttctatt ccaaaaagtc
     7141 caagtaagat gatgaatcgg ttacataaaa tagcagtcat tggagccggt tcctggggca
     7201 cggccctctc catggttctg gcgacccggg aatgtgaagt cgtcctgtgg acgccggaag
     7261 aggctcaggc caggcagctt gccgaaacaa gacgcagccc cgtcctttcg aaaaccgccc
     7321 ttcccctggc ccccaatatc catcctactt gcgatctggg ccaggtgaag gatgcggaac
     7381 tcattgtagt agtggtacct tccgtggcca tgcgttccgt ggcccagcgg ctgcgcagcc
     7441 tgccggtgca gccggatgcc gtcattgtct cctgcaccaa gggcattgaa cagggaaccc
     7501 ataaaagaat gacggaaatc cttcaggaat atctgccctc caaccccata ggcgtgcttt
     7561 ccggtcccaa tcatgcggaa gatatctgcc tgggccttcc gtccgcctcc ctgattggat
     7621 ttgaagatcc gaagtatgcg gattgggtgc agcagatatt tgcatccaaa accttccgtg
     7681 tttattccgc tacggacatt atcggcatgc agctgggcgg aaccattaag aacgtctttg
     7741 ccatcggggc cggcttatgc gaagggctga acctggggga taacgcccag gccgctttgc
     7801 tgacccgcgg cctggcggaa atgacgcgca tcggcgtggc cagcggaggc cgcagggaaa
     7861 ccttcatggg cctttccgga gtaggcgatt tgattgttac ctgctattcc cgccactccc
     7921 gcaaccagac ggtggggcgg aggctggcgg aagggaaaag cctccaggaa atcctggata
     7981 ctctgggaat ggtggcggaa ggggtgccca acacgctttc cgtctatgaa attgcacggg
     8041 agctggatgt gaggacgccc ctgattgacg ccgtttattc cgttctttat gagtccaaac
     8101 ctcctatgga agcacttgcg gaactcatga cgcgtgaccc ccggccggag tcagattgat
     8161 tttctgtttt tttgagttgc ttttcctcga caaattatac tatataaaca atcagtatga
     8221 aacgtgccat catctcagct ctttttgccg ccggcgtcct tggcgtcgcc agtgcggaca
     8281 ttcaggctcc ccccgcttcc gaatacaccc ccacccgcaa gctgggccgc gccatcgcca
     8341 accttattta ttccgttgaa gaaatcccgc tgggaatcat caactggacg agccgcgagg
     8401 gggattatgc cggtttttcc gtaggcattg ttgatggcac cgcgaccatg tttgagcgca
     8461 tgggctacgg aatctatgaa cttgtcacct tctgggctcc cacttacaaa tgcacgtaca
     8521 agcctcctta tcagggacgt tgcggcatga gcggccttaa ggaatacaat cccaatggcg
     8581 gtctgagcga attccctgcg gaactcggct tccagagcta ctacaagtat tcacgccagc
     8641 agcgtgacta aggtcggcct gttaaaaatt tcaaaagggc tgtccgcttg cttgcggaca
     8701 gtcctttttt cataccgtgg ccctgacaat agccgccatt gacggggaag ggaggaaaac
     8761 gtattcttcc atgccggaaa ggcttccata tcatgaataa aaccgctgct ttcattggct
     8821 tgggcgctgc cgtttgcata acagctccct catttgccca ggactcccat ctttccctga
     8881 ccagacagag cgttgccagc atgcatgaaa ttacggcagc cttggataag gtgacggatg
     8941 aacccggagc tgccgctgct gtggaaacag ttaaaaaagt gcgcaaaaaa ctgctggatc
     9001 ttggaaaaag gcagctggaa cttcccggtg ccacactcca ggagcaggct caggtttctg
     9061 cccagatgac ggaagtgcag aaaatttccg acgaattggt aaaatccctg gcccgtttaa
     9121 aaaaggaagg actgcttacg cccgatttgc aaaaagccct ggcggatttg cggtctgttc
     9181 agacggaact ggcgcaggct tcccgggaca aggctgagca ggcggagccg ttcccggagg
     9241 atgcagaggg caatacgcat gaaaccctgc tggtcaaaac tgtggatgaa gtcaaaaagc
     9301 ttgatgattc cctggccaag gtaagggatg aagaaaccgg caaggctgct gtggaacaga
     9361 taggccgtta ccgggcggct ttgctggacg ttgccaggaa acaggccgcc ctgccgcccc
     9421 tcacccgcaa ccagcaggcc aagctgatgg gagtacagca gcagcttgtg gaaatgatgc
     9481 aacccattgt caagcatgtg acggccatca tgctttctcc ggatgcttcc aagaacctga
     9541 aggaagcagt gaattccctt tccgaattac ctaaggaagt tcagaaaatc cgtgaagagg
     9601 cggctaagtg aactttttaa aggatgcgtc cttttgggct ggtcaaaaaa ttataattgt
     9661 tctaaattgg ctgtcctgaa aaatgcgccc ggtttttagt gaaacagatc tcaatgaacg
     9721 ccccttcctg gtcttctggg aagtgacgcg cgcttgcgcg cttgcgtgca ggcattgccg
     9781 cgctgtcgcc cagccgcgtc cgcacccgga tgaattgact catgaggagg cattgcgcct
     9841 gattgaccag ttggcggaac tgcggcctcc catgctggtg ctgacgggcg gcgacccggt
     9901 catgaggccg gatattctgg aattggtccg tgcggcttcc ggcaaagggc tgcatgtagc
     9961 attgagcccg gctgctaccg cccggctgct gcacacggat ttccgtgcat tgaaagaagc
    10021 tggagtccag agcatgtcat tgagcctgga cggcgcgcat gagagcaccc atgacgcctt
    10081 ccgcggcgtc ccccacacat atgaacggac tctccgggct gcggaaatgg cgaaggaagc
    10141 cggcatgcat ttgcaaatca acaccaccat caccaagagc acactgggcg aatttgacga
    10201 ctttgtggag ctgatgaaaa gaatgaagcc gggcatgtgg agcgtatttc ttctggtgcc
    10261 cacaggccgc gccgccatgg atgaaatgcc tgcggcggaa gaagtggaag ccatctggaa
    10321 gaaactgagc aggataagcc atgaggtatc cttcggcgtt aaaactacgg aagggcacca
    10381 ttatcgccgc gtggcgcttc aggaagcccg cgctcaggga agcaagcccg cccgccgcgc
    10441 cattcccacc cgggacggca aaggcattat gtttatttcc cataccgggg aaatccagcc
    10501 ctccggtttt cttcccatga cggcaggaaa cgtccggacg gatgaccctg gagaaatcta
    10561 ccgcacgcat cctcttttcc tcaagctccg ggatgacaac gcgttgcagg gcaaatgcgg
    10621 gcggtgtgag taccgtacta tctgcggagg ttcccggtcc cgtgcttatg ccgtttacgg
    10681 agacatgatg gcggaagaca acctctgccc ttatcagccc aggctttcac aacaccatga
    10741 ttaatattac cagactttgg acaggggcgg aacagcccgc ggaccatttg agatacgggc
    10801 agggccacgg gcacggccgt tttgcagggg gcgccgcgga atcctgtgcg ccggcttcgt
    10861 cccgtatgcg caagcccatt gtggtctgga acattacacg cacctgcaat ctcaaatgcg
    10921 tacactgtta tgcggatgct tctgcccgga aatttaaggg agagctggat tgggagcagt
    10981 gttgcgcagt cattgatgat ttggcggact acaaggtgaa cgccctcctt ttttcaggag
    11041 gggagccgct ggtgcatcct cgttttatgg aactgctgga acgtgccacc gggaaagggc
    11101 tgaaagtgac catttccaca aacggtaccc gcatcacgcc ggaagctgca gcgcggttca
    11161 aggaactggg cgtggcgtac gtaggcattt ccctggacgg cattggcgct gttcatgaca
    11221 aattccgcgg tgtggaaggt tcttttgagc aggcggtgcg tgggttcagg ctttgcagcg
    11281 aagtggggca gaagacgggc ctgcgcctga cgctgacccg caacaatgtg cagtgcatgg
    11341 gccagatttt ggactttatt gacgccaacg acatccagcg cgtctgtttt taccatctgg
    11401 ttcccactgg ccgcggtgtg gaagtgcaga ccctgactca ggaagaagcg cggaatgcca
    11461 tggatacgct gattgcccgt gtggaggaat ggaaagcgga gggaaaaaac cgtgaggtgc
    11521 tgactgtgac ccagcctgcg gacggcattt acctgcttct gcgccagctc cgggaaggtt
    11581 cccccctggc gaaggaaacc cttggcctgc tccagtggaa tggcggcggc gcgaacagtt
    11641 ccggccgggg catcgccaac attgacacgc agggagccgt gcatccggac cagttctggc
    11701 aatccgttac tctgggtaac gtgaagagtg accggttttc cgatttatgg gatgccaggg
    11761 ccggagctgc ggtggaaatg ctgcctgagc tgcgcggctc tgacgaccct ctggaacggc
    11821 agaaaaaaat tgaaggccgt tgcggccgct gcgctcattt cgccctgtgc ggcggaggtt
    11881 tccgtacccg tgccgcgttt gcccatgggc actggtacgg atcagatccc ggctgctatc
    11941 tgacggaaga ggaaatttcc acccccttgc cggaaatcag gtaatgatgt ccccggcttc
    12001 attcgccgga acacggttgc ctccgggaaa gggtgattgg cggaattgcc gtctcattct
    12061 atcgtgggag tctcccgcac gcaggtaaaa cgcccctgtc tttgcagctg atttaccggg
    12121 aacagggggg ggtgtgcagg gaaaaacaca ggtgcgtgtt tcggcgggga atggggcgaa
    12181 tttgtccata tgtctggttt tccctgcttt acaaggcagg cggcatggca tagcatgccc
    12241 cgcatgatga gtcaggaatt gagaccggag accctgtgcg tacaggcggg ctgggcgcct
    12301 aaaaagggtg aaccccgcgt attgcccatt taccagagca cgacgttcaa gtacgaaacc
    12361 agcgaacaaa tggcaaagtt gtttgatctg gaagaagccg gattctttta tacgcgcctc
    12421 cagaacccca ccaatgaggc ggttgccaga aaaattgccg aactggaagg cggcgtggcc
    12481 gccatcctga cgtcttccgg ccaggcggct tccttctttg ccgttttcaa tatttgcgag
    12541 gctggagatc atatcgtcag tgctgcggcc atttacggag gcacatacaa cctttttgcc
    12601 gtcacattcc ggaaaatggg cattgaagtc actttcgtgg accaggacgc cccgccggag
    12661 gaaatctcca aagcgttccg tcccaacacg aaagctttct ttgcggaaac tatttccaat
    12721 cccacgcttt gcgtgctgga tatccgtaaa atggcggaca ttgcccatgc gcacggcgtt
    12781 cccctcattg tggacaatac ctttgccact cccattaatt gccgtccgtt tgaatggggc
    12841 gcggatatcg tcactcactc caccaccaag tatatggacg gtcatgccgc cgccgtaggc
    12901 ggcgtgattg tggacagcgg caactttgac tgggaagcgc acaaggatca gttcccgggt
    12961 ttgactgaac cggacccctc ctatcacggg ctctcctaca gcaaaagctt cggcaagggc
    13021 gcctacatca ccaaggcgac tgtccagctc atgcgcgacc tgggttccat tcagtctccg
    13081 cagaatgcct ttttgctcaa tctggggctg gaaaccctcc atctgcgcgt gccgcggcac
    13141 tgtgaaaacg cgcaaaaagt ggcggaattc ctgcaagggc aggaagatgt tgcctggatt
    13201 aattatccgg ggctttcttc caatgagtat tatgaattgg cgcagaagca attccgaggt
    13261 ggacaatctt gtggtgtggt aaccttcggc atcaagggag gccgtgaacg ttccatcaag
    13321 ttcatggaca gtctgaaact ggccgctatc gtgacccatg tggcggattc ccgtacctgc
    13381 gttctccatc ccgccagcca tacgcaccgc cagttgacgg atgagcagct catggaggcg
    13441 ggcgtacggc ctgacctcat ccggttttcc gtagggacgg aagctgcgga agacattatt
    13501 gcggacctca aacaggcttt ggaagctatt cgttaaaaag tcttcttgga aaaagccgcc
    13561 tcactttgct gaggcggctt tttctttatc attaaggatt ggataaaggg gacagcggat
//
