LOCUS       c00157_gnlPro..         4377 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KPKPEKPM_157.
ACCESSION   c00157_gnlPro..
VERSION     c00157_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:11:42
            Original ID  :: gnl|Prokka|KPKPEKPM_157
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4377
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4377
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[420:4375]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      421..4375
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4377
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4377
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..413)
                     /locus_tag="ctg157_1"
                     /transl_table=11
                     /translation="VVCELPQQKRIMDKDKSKIGEFHFVTEPYLLDFRGRVTIPMIGNY
                     LIHVASSHAAERGFGFNDMSERHTAWVLSRLAIEMIEYPAMSEPITLYTWVDEVGRLFT
                     SRCFELVDGNGKTFGYARSIWAAIDVETRRPTL"
     CDS             complement(421..972)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_2"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-18, bitscore: 54.1,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENTVGLLNQITIIFTRRQLNIETLSVSPSAIQ
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVFQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNETCVVLEKSGHYDETQALFRELSETIGVLQFIRSGRIAITKS
                     RVERLSDMLADMERKLQEKK"
     CDS             complement(989..2698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.2e-52, bitscore:
                     163.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKSLIAEGVDTIFGYPGGQAIPIYDSLYDYRDK
                     LKHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGFVDYEYKKVDYIRSYQPEPDINQDRIKAAAALINKAEKPFCLVGQGVLLGG
                     AEEELKAFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKVIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFELDAQEEYEKVIEKELYPMNGSLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKRTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLDVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRTVE
                     KREELDEAIAEMLNHNGAFVLVXXXXXXXXXXXXXXXXXXXXXKRNEYDIRR"
     CDS             complement(2732..4375)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_4"
                     /sec_met_domain="ILVD_EDD (E-value: 4.6e-200, bitscore:
                     653.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNIAMGGSTNTVLHLLAVA
                     QEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAGLVDGS
                     TRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELDTDRAE
                     GCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDAACEGI
                     LGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGGTSGLS
                     IGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKKAFTPP
                     TRQREVSKALRAYGKMVSSADKGGVRIVED"
ORIGIN
        1 aataaggtag gacggcgggt ctccacgtcg atagccgccc aaatagaacg ggcgtaaccg
       61 aatgtcttac cgttgccatc caccagctcg aaacaacggc tggtaaagag acggccgact
      121 tcatccaccc aggtataaag agttataggt tcggacatgg ctggatattc gatcatttcg
      181 atcgccagac gggaaagaac ccaagccgta tgccgttctg acatatcgtt gaaaccgaat
      241 ccgcgttcag cagcatggct ggatgcgaca tgtatcagat agtttccgat catcggtatc
      301 gttacacgtc cacgaaaatc caacaggtac ggttccgtga cgaaatgaaa ttcccctatt
      361 ttgcttttat ctttatccat gattcttttc tgttggggca gttcgcaaac cacccgtacg
      421 ttattttttt tcctgcaact tacgttccat atcggccaac atatcgctca aacgctcgac
      481 acggcttttt gtgatcgcaa tgcgaccgga acggatgaac tgcaagacac cgatcgtttc
      541 gctcaactcc ctgaaaaggg cttgcgtctc atcgtaatga ccactctttt cgagaacgac
      601 acacgtttcg ttcatttcca gaatacgggc gttatatttg cgaatcagat cctcgaccgt
      661 ccccatcttg ataaacagct cggtgctcag cttataaagg gcgatctcct ggaaaaccag
      721 atcttcatcc gtattatagt aagccttcaa gatatccacc cgtttgtcga tctgcttcac
      781 aaccttgtcg atcatatctt catcggcaaa tgtcgtgatc gtaaatttat gtataccctg
      841 tatggcggaa ggtgaaacgg aaagcgtctc gatgttcaac tgccgacgcg taaagataat
      901 cgtaatctgg ttcagaagac ctactgtatt ctctgaaaag ataataacgg tatataattt
      961 tttagttgtc atagcttcac ctccttactt atctcctaat atcatattcg ttacgcttcn
     1021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     1081 ngaccaacac aaacgctccg ttatggttca acatctcggc aatagcctca tccagttcct
     1141 cccgtttttc aacggtgcgg ccagcgatac cgtacgcttt cgcgatcgcc acgaaatccg
     1201 ggttctccat gatcgtattc gaataacgtt cgtggaagaa caactcctgc cactgacgta
     1261 ccattcctaa gaaattatta ttaaggatga tgattttcac atccagtttt tcctgcataa
     1321 tggttcccaa ctcctgaatc gtcatctgca tcccaccgtc accggtaaag aagcagaccg
     1381 tacggtcagg tgcaccgaac ttggctccca tagcagcggg aaggccaaag cccatcgtcc
     1441 ccagaccacc tgaagtaacc acgctacgag tgcgtttata tttgaaatag cggacaccca
     1501 tcatctggtt ctgtccgaca tccgtaacta aaacagcatc gtttccagtc gcctcggaca
     1561 cttttcgaac gacttcaccc attttcaaag atccgttcat cggatacaac tccttctcga
     1621 tcaccttttc atactcttcc tgtgcatcca gctcaaactc agcattccac tccggacgtt
     1681 tccgttcttc caacaacgca gttatcatcg gaatggtatg tttggcattt ccgagaacct
     1741 tcacatcgac cggtacattc ttcccgatct ccgagttgtc gatatccaaa tggatcactt
     1801 tcgcctgctt ggcgtatgtc ttcaaatcgc cagtaacacg atcgtcgaaa cgcataccga
     1861 tggcgatcaa cacgtcacat tcattggtct tcctattcgg accgacattg ccgtgcatac
     1921 ccaacatacc cttattcaaa ggaaaatcgg aaggcaacgc cgatagaccg agaacagtcg
     1981 aaccggcagg aatgtcattc ttcagcagga atgctttcag ctcctcttca gcacctccca
     2041 acaaaacccc ctgtccgacc aggcagaacg gtttctccgc tttattgatc aacgcggcag
     2101 ccgctttaat ccgatcctgg ttgatatccg gttccggctg atagctgcgg atatagtcta
     2161 ctttcttata ttcataatcc acaaatccaa cctgagcatc ctttgccaaa tcgagtacaa
     2221 caggccccgg ccgtccggta gaagcgatat aaaaagcacg tgaaacagcc cacgctatct
     2281 cttccggctt gcgaatctgg tacgcccatt tggtgatcgg ttgcgtaatg ccgatcacat
     2341 cgacttcctg gaaagcatct gttccaagca atggagaagg gacctgtccg gctatgacca
     2401 ccataggagt gctgtccatc agtgcatcgg caatgccggt gatggtattt gttgcgccgg
     2461 gtcctgaagt aaccaacgtc acccctactt taccggatac acgggcatac ccttgtgcag
     2521 catgcgtcgc cccttgttca tgacgcacca atacatgctt caatttatcc ctgtaatcgt
     2581 acaaactatc gtaaatagga atcgcttgcc cgccgggata accgaaaatc gtatctactc
     2641 cttcagctat cagtgacttc agcaaagctt ccgaaccggt tatcttttgt ttctccataa
     2701 aaaataacgt gtttaatgta tattattggc tttaatcttc aacaatcctt acacctccct
     2761 tatcggcgga gctaaccatc ttcccgtacg ctctcaacgc tttcgagacc tcacgctgac
     2821 gcgtcggcgg cgtaaaggct ttctttccac gtgcctcttc cgccttacgg cgctcggcca
     2881 actcctcgtc gctcaaccgc acgttgatgg aacgttccgg gatattgatc tcgatgatat
     2941 ccccgtctct caccagtccg atagcgccac cggaagcggc ctcgggagag atatgcccga
     3001 tagaaagacc ggacgtaccg ccactgaaac gaccatccgt gatcaaggcg cactccttac
     3061 ctaagtgacg gctctttata taagaggtag gatataacat ctcttgcatt cccggccccc
     3121 ctttcggacc ctcatacgtg atgacgacca catcgcctga aacgaccttg cctcctaaaa
     3181 tgccctcgca agcggcatcc tgtgaatcga agactttcgc cgggccggag aatttccaaa
     3241 tactctcatc cacaccggcg gtttttacga cacatccgtc caaggcgata ttccctctca
     3301 aaacagccaa gccgccatcc ttggaataag cgtgctccac gtcacggata caaccttcgg
     3361 cacgatccgt atctaattcc ttataataag attcttggga acccatctgg atactgaacc
     3421 gatgagcggg agcgctcttg tatttacgga tcgcctcctc cgttacgttc ggggaagtga
     3481 cggcgtattt atcaacagcc tcggccaagg tcaggccgtc cgcacgtctc gtgctgccat
     3541 ccacaagccc ggctttcatc aactcgttca tgataccgag gattccaccg gcacggttta
     3601 cgtcttgtac atgataagtg tgcgtattcg gggctacctt acacaggcaa ggagtcttgc
     3661 gggataacat atcgatatcc tccatatgaa aatcggcgcc ggcttcttgt gccacggcca
     3721 ataagtgaag caccgtattg gtagaccccc ccatggcgat attcaagaaa gcctgacggg
     3781 tagcgatgtt gcgaggtaac acggaatcat ccccgtcacg atagtatttg taagcgttct
     3841 caacgatttg cttagccgcg tcacggaaaa gttggatacg gttcttatgg gtagccacga
     3901 tcgtcccgtt acccggaagc gccagaccga tcgcctcgtt caagcagttc atagagttag
     3961 cggtaaacat accggaacaa caaccgcaac ccggacacgc atggcgttcc acctgctcga
     4021 tacgctcatc gcttaccgat gtatcggcag actcaatcat cgcatcgatc aaatcaagat
     4081 ggcggccatc cagctcacct gcctccatcg ggccaccgga cacgaacacc gtcgggatat
     4141 ttaatcgcat ggaagccata agcatacccg gcgtgatctt atcgcaattg ctgatgcaaa
     4201 ccatagcgtc cgccttatgg gcattcacca tatattccac gctgtccgcg ataatgtcgc
     4261 gtgaaggaag cgagtaaagc atcccatcgt gccccatagc gataccgtcg tcgatagcga
     4321 tcgtattaaa ttcagcggcg aaacaacctt gtttctcgat ctcggccttg accaatt
//
