LOCUS       c00014_gnlPro..        13487 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIBBIEJD_14.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:14:50
            Original ID  :: gnl|Prokka|HIBBIEJD_14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13487
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13487
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[16:3487]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      17..3487
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13487
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13487
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             17..715
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_1"
                     /sec_met_domain="SucD_FumR (E-value: 4.2e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             752..2698
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.7; E-value:
                     2.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-61, bitscore:
                     199.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.9e-37,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             2732..3487
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_3"
                     /sec_met_domain="Fer4_7 (E-value: 5.3e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.7e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(3626..4573)
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(4638..5606)
                     /locus_tag="ctg14_5"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATTMASVATFDAMKEFMAAVKVTYSAPDWSLTGGTYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAAGAIYPSITYTVADVAAQTDLVAAKATDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSIWKSQEGTATYA
                     HTIDDGALEVNTTGVEVNTAWMLMPQTLDTNAKINVVYDIYEKDVLLDTVTSAIDLNDT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             complement(5652..6635)
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSGVQIKLDW
                     KGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNTESIQIRG
                     DESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLNWKPEAVVDH
                     YSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLLWGYFSSF
                     VLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPDVGVPGSE
                     IHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             complement(6632..7255)
                     /locus_tag="ctg14_7"
                     /transl_table=11
                     /translation="MGKRIFIYVFWLLLFCMMSGQVIGQNKSVESHSHTCKTVLALKNN
                     LLYDLALAPNIEVELPLGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHT
                     RGRLSGHFLGAYAEGGTYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIG
                     YLDTEYRKYTSYGNDLVWVSSGKYHFIGPTKAKISLVWLLTSGR"
     CDS             7816..8484
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MASVDSCIKYGVGNIECDVCISKDSVFYVLHDSTLDRTTNGTGAI
                     SQWLSTDIDTLDAGSWFAPRFAGQRVLRLTDLLRKAKEHGLRITIDYRNGGLHQLLDLI
                     KDEGMLENCNFTFSKEYHAKCFRKMAPEVRTLQAYIKSEKDIEHVVKELHPDIAVVWID
                     SLTPQFVKKCREHNLQVLALVLGLDDKTEENQKAVDLGVDIIATDHPEKFIMKYGKPSI
                     "
     CDS             complement(8504..9622)
                     /locus_tag="ctg14_9"
                     /transl_table=11
                     /translation="MNSDERICSIALTLCPGIGHIGAKRLIEGMGSAAEVFSRRKELPE
                     IMPGVNPGVVTALDCPAAFLRAEQEMEFVEKNRLSCLTLKDEAYPSRLRECEDAPIVLF
                     FKGNTDFNRLHVIDMVGTRRATDYGKQFCADFLRDLAVLCPDVLVVSGLAYGIDIHAHR
                     AALANHLPTVAVLAHGLDRIYPYVHRKTAIDMLAQGGLLTEFLTGTNPDKHNFVSRNRI
                     VAGMSDATIVVESAAKGGSLITAELAEGYHRDCFAVPGRVTDESSIGCNRLIRDNKAAL
                     IQSAEEFVQIMGWAVAEQPARTEGIQRNLFPELTEEEELVMRILMRQGDLHINAMVVEA
                     DIPVNRMSALLFELEMKGVVKAMVGGVYHLLT"
     CDS             complement(9634..10050)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_10"
                     /sec_met_domain="HBT (E-value: 9.9e-12, bitscore: 37.2,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 2e-10, bitscore: 33.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYIYELPMKVRDYECDLQGIVNNANYQHYLEHTRHEFLLSAGVS
                     FAGLHEQGVDPVVARINMAFKTPLRSGDEFVSKLYMKKEGIKYVFYQDIFRASDGKVCL
                     KGIVETVCVVNGRLSDSELFDRLFAPYLNPCESV"
     CDS             complement(10082..11374)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_11"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.5e-71, bitscore:
                     232.2, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKHSISDFEIMAPVGSRESLAAAIQAGADSIYFGIENLNMRARS
                     ANTFTIDDLREIARTCDEHGMKSYLTVNTIIYDHDIPLMRTIVDAAKAAGISAVIAADV
                     AVMSYARQIGQEVHLSTQLNISNVEALRFYAQFADVVVLARELNLEQVAEIYRHIREEN
                     ICGPSGEQIRIEMFCHGALCMAVSGKCYLSLHEMNHSANRGACMQVCRRSYTVRDKETD
                     VELEVDNQYIMSPKDLKTIHFMNKMLDAGVRVFKIEGRARGPEYVRTVVECYKEAIRSY
                     LDDTFTDEKIARWDERLKTVFNRGFWDGYYLGQRLGEWTKNYGSAATERKIYVGKGIRY
                     FSNIGVAEFLVEAAEVSVGDKLLITGPTTGAEFVTLDEARVDLKPVQTVKKGQHFSMKS
                     VKIRPSDKLYKLVSVEELKKFKGLDVEKQRG"
     CDS             11444..12424
                     /locus_tag="ctg14_12"
                     /transl_table=11
                     /translation="MKIKDIDLGPRPVFLAPMEDVTDPAFRLMCKHFGADMVYTEFVSA
                     DALIRSVGKTQQKLNISDEERPVAIQIYGRDTATMVEAARIVEQAHPDTLDINFGCPVK
                     RVAGKGAGAGMLQNIPLMLEITRAVVDAVKIPVTVKTRLGWDANSKIIVDLAEQLQDCG
                     IAVLTIHGRTRAQMYTGEADWTLIGEVKKNPRMHIPIIGNGDITTPQRAKECFDLYGVD
                     AIMIGRASFGRPWFFKEVKHYLETGEELPPLSSEWRLNVLRQEVEDSVNLLDERRGILH
                     VRRHLAASPLFKGIPNFRDTRIAMLRAETKEELYRIFEEIEPLLP"
     CDS             12783..12908
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="MKKKKLLKQLIVNFQHSLPAEVYPRTLVLPTDSGKIITVPD"
ORIGIN
        1 ttaaattcaa tcatttatgt ggttaagtaa ttcatctgta ggaaggaaag tggtgatgag
       61 cgttaccggt atcgcccttg tcctgtttct gacatttcac atggcgatga acctggttgc
      121 attagtctcg gctaatggct acaacatggt ttgtgagttc ctgggagcaa actggtacgc
      181 attggtggct acggtaggtc tggctgcctt attcatcatc cacatcatct acgctttctg
      241 gctgactatg cagaaccgta aggcacgtgg tagcgaacgc tatgccgtta cggaaaagcc
      301 caagactgtg gaatgggctt ctcagaacat gctcgtactg ggtatcatcg taatcgtggg
      361 tttgggcctg cacctggtaa acttctgggc taaaatgcag cttcccgagt tgatgcacaa
      421 catgggcatg catgccgaca ccctcacgct ggcatatgca gccaacggtg tctatcacat
      481 tcaaaacacc ttcagcaatc cggtattcgt agtgctttac ctcgtttggc tgggcgcatt
      541 gtggttccac ctcactcacg gtttctggag ctccatgcag tctttgggct ggaacaacaa
      601 agtatggatt aaccgttgga aatgtatctc caacatctat tctactatcg ttgtcctctg
      661 cttcgctctg gtagttgtcg tattctttgc aaaatcattg tgcggcgctt gctaaattca
      721 aattgtaaat gactaaattg taaattgcat tatgactaag atagattcta aaataccgga
      781 aggaccggtg gctgagaaat ggaccaatta taaggctcac caaaaattag taaaccctgc
      841 caacaaacgt cgtctggaca tcatcgtagt aggaaccgga cttgccggtg ccagtgctgc
      901 cgcctctctg ggcgaaatgg gtttcagagt attcaacttc tgcatccagg actctccgcg
      961 ccgtgcacac tccatcgctg cacaaggtgg tatcaatgct gctaagaatt accaaaacga
     1021 cggtgactct gtataccgtc tgttctacga tacagtaaag ggtggcgact accgtgcccg
     1081 cgaagccaac gtttaccgtc tggctgaagt atccaacaat attatcgacc aatgcgttgc
     1141 acaaggtgtt cctttcgccc gcgaatacgg cggtacactg gacaaccgtt ctttcggtgg
     1201 tgctcaggta tcccgtactt tctatgccaa gggtcagacc ggacagcagc tgttgctggg
     1261 tgcatactct gcattgagcc gccaggtgaa cgtaggcact gtgaaactgt atacccgcta
     1321 cgaaatggaa gacgttgtcc tcattgacgg acgtgcccgc ggtatcattg caaagaacct
     1381 cgttaccggt aaattggaac gttttgccgc ccacgctgtg gtaatcgcta ccggtggtta
     1441 cggcaatgcc tacttccttt ctaccaatgc aatggcatgt aactgctctg cagcaatggc
     1501 ttgctaccgt aaaggtgcct ggtttgccaa ccctgcttac gtacagattc accccacttg
     1561 tatcccggtt cacggtgaca agcagtctaa gctgactttg atgtccgaat ctctgcgtaa
     1621 cgatggtcgt atctgggttc cgaagaagct ggaagatgcc aagaaactgc aggaaggtac
     1681 actgcaagga aaagatattc ccgaggaaga ccgcgactac tacctggaac gccgttatcc
     1741 ggcattcggt aacctcgttc cgcgtgacgt tgccagccgc gctgccaaag aacgctgcga
     1801 caagggcttc ggcgtgaaca acaccggtct tgccgtattc cttgacttct ccgaagctat
     1861 caaccgtctg ggtaaagatg tcgttgcaca acgttacggc aacctcttcg atatgtatga
     1921 agaaatcact gatgtcagcc catacgaaaa cccgatgatg atttatccgg ctatccacta
     1981 taccatgggt ggtatctggg ttgactacga actgatgacc tccatcaagg gactgttcgc
     2041 catcggtgaa tgtaacttct ccgaccacgg tgcaaaccgc ctcggtgctt ccgccctgat
     2101 gcaaggtctg gccgatggtt acttcgtatt gccttacact atccagaact atctggccga
     2161 ccagattaca gttcctcgtt tctctaccga cctgcccgaa tttgcagctg cagaaaaggc
     2221 cgttcaggag aagattgact ggatgatgaa catcaagggt aagaagtctg tagactctat
     2281 ccacaaggaa ctgggccaca ttatgtggga atatgtaggt atgggacgta cggccgaagg
     2341 cttgaaagaa ggtctgaaga agctgaaaga agtccgcaag gagttcgaga aagaactgtt
     2401 catcccgggc gacaaggaag gtatgaatgt agaactcgac aaggctatcc gtctgtacga
     2461 cttcatcact atgggcgagc tggttgctta cgatgcactg aaccgtaacg aaagctgcgg
     2521 cggtcacttc cgtgaagaat atcagactga agaaggcgaa gccaagcgtg acgatgaaaa
     2581 ctacttctac gtggcttgct gggaatatca gggttctgac gaaaaggaac cggtattgct
     2641 gaaagagccg ctggtttacg aagcaatcaa ggtacagact cgtaactaca agagctaatc
     2701 gggaagttga acatttaaag aattaaagaa aatggataaa aatatatcat ttacgctcaa
     2761 ggtatggcgc cagaagggtc cgaaagcaaa aggcgctttt gaaacatacc aaatgaaaga
     2821 tatcccgggc gatacttcat tcctcgaaat gctggatatc ttgaacgaac agctgatttc
     2881 tgaaggtaaa gaaccggttg tattcgacca cgactgccgc gaaggtatct gcggtatgtg
     2941 ttcgctctac atcaacggac acccccacgg tcctgcaacc ggcgctacta cttgccaaat
     3001 ttatatgcgt cgtttcaacg acggcgatac catcactgtt gaaccgtggc gctctgccgg
     3061 tttcccggtt atcaaggact tgatggtcga ccgtacggcc tacgacaaga ttatgcaggc
     3121 aggcggctac gtcagcgtac gtaccggtgc tccccaggat gccaacgcta tcctgattcc
     3181 gaagcccatc gctgacgagg ctatggatgc tgccagctgt atcggttgtg gtgcttgtgt
     3241 ggctgcttgt aagaacggtt ctgctatgct gttcgtttct gccaaggtga gccagctgaa
     3301 cctgttgccc caaggcaaac cggaagcatt gcgccgtgcc aaggctatgt tgagcaagat
     3361 ggacgaactc ggtttcggta actgtacaaa cactcgtgcg tgcgaagctg aatgcccgaa
     3421 gaatgtttcc atcagcaaca ttgctcgcct gaaccgcgac tttatcattg cgaaactgaa
     3481 agactaatcc ggtctttctg caaataatat aggatgcgct tcggataaac cttttgagca
     3541 agctcagatt tatcactcag ctttcactat atttgattaa tatcacaaga gactcctctg
     3601 ccgggaaacc gccggaggag tttttttatg acatgccgtt tacttcagat aaattgccgg
     3661 cacgcaagct acggggagaa gccccgaaat tctttttgca gaaattggaa aaatgaggca
     3721 gcgattcaaa gccatattta tagcaaatct ctgatataga agcatccgta taacgaagtt
     3781 cataaaccac gctttccttc ctccgttcca tcatccactc gtacaccggt tgatgaaaaa
     3841 cagaattgaa tatacgccgg aaagtagcta ctgtatatcc tcccaactgg gcaagttcct
     3901 ctaccgtctt gactttggca tgattctgca agacaaagta gtggaaggaa ttagtatact
     3961 gggcaagagg atgtatcagc atggaaagct catagtcgga gtagtaattt ccaagaatga
     4021 aagcaagttc tttccgtttg aaacaaagca tttcccggca aatcttctcc tcggacaaat
     4081 aggccttgga actttccaga aagagctgca actcgggagt aatggtcaaa ggatagaata
     4141 tcaatggagg ggtaacctct ttcataatat ggttataccg gtcctcacag aagaattcag
     4201 gcttactgaa ccggtaacaa acgcattcca catccgtcat ggcaagtatt tcgtacttgg
     4261 aaccaatagc ttgaaggatg aactcacctg catgcaacac agttcccgca tactccttac
     4321 tgttgacaag cacttctcct ttcagcagga aaattataat attttcctca cactttcgcg
     4381 ccggcagatg gaatcctctg aggtgggaag catatattat tgcattgtcc acagccttgg
     4441 gacattgagc gcattgtttt ttacctctgc aagcagaaga gttgggcatc ggcaagtaga
     4501 tttgtttgtt tgttgcagtg acaaaaatag ataaataata ctcataaaag aaacattccc
     4561 cgaaaacttt cataaagaag tttcggggaa tgaataaaat agaagtaatt cagtttttta
     4621 ttgcggacag tgccgtttta tttttccacg ttcgtatcat cagccgtact ccatggacca
     4681 acttcaggta caaaggttac ttttgccgcc ttattggcca gcgtcagcgt ataacgtatc
     4741 tttttgcctt caccccaggc ttgtgtatca ttcaagtcaa tggcggaagt tacagtatca
     4801 agaagaacgt ctttctcata gatgtcatag acaacattga ttttggcatt cgtatccaac
     4861 gtctggggca tcaacatcca ggctgtattc acttccacac ccgttgtatt cacttccaat
     4921 gcaccatcgt caatcgtatg tgcataagtg gctgttcctt cctgtgactt ccatattgaa
     4981 tcatcaaaac cataagttcc tttattgtgc acaccggata ttgtaagtgt tttcagttta
     5041 taagtcaaag cgtcggctgc cttgacagtg aaatttattt gggtcagtat atggccgaat
     5101 ttcaaagata ccccactggc atttgatgcc ttggttgcat ccgtcgcttt cgcggctacc
     5161 aagtccgttt gggcagctac atccgctacc gtataagtaa tggaaggata tatagcacca
     5221 gcagccggtt gattgtacgt caaggccccg gtacccggat tcccgtaagc aaagaactgc
     5281 aagttatccg tcattggcca ataatatgtt cccccagtca aactccagtc gggagcacta
     5341 taagttacct taacagctgc catgaattcc ttcatcgcat caaaagtcgc aacggaggcc
     5401 attgttgttg ctcccgtatt ataagcatac acagtgaacc ctaccttctg caattccggc
     5461 aaatcagtca ctgtggctct cgtagtgtta cccactactg ttcccaattt aatctccgcc
     5521 ttttgtccgg cattctctat ctcctcactt tccgagcaac tcattactgc tgctgcagcc
     5581 aaagccaaaa ataaaacctt cttcataatt gtctgttatt aaagttaata tatttatttg
     5641 tctgtttgct atcaattcac cggtagctcc acatccgtct catcatccca atcatccaca
     5701 tcgccaccaa tccctccatc tccttcatcg gttcccggtt ccaaatcatc caccacaacc
     5761 ttgtcctccg gtacgggaac ctcgatatgg atttccgacc caggaacgcc cacatcaggt
     5821 tcttcttcgc ctcctcccga gggaggagct gtttcaatca cttccgtgat atccaccttc
     5881 acctcttgaa ccgttttatc tcgtttcaca atcttcagtg tcagcaacat aggactatcc
     5941 gcacgggtct tggtatcttt cagtaataca aaactggaga aataccccca taaaagcccg
     6001 ttttcacgct ttgtatccac acatataggt acctcgctca aatggcaagc acggttgcct
     6061 ataaagtaac ttccgttcaa gccgtccaca tggcagatga tgctcgatat tctatcccat
     6121 ccttccacct ttatatcaaa ggaataatgg tccactaccg cttccggctt ccagttcaac
     6181 ggaagcgcca catcactctg ccttatttcc acctcgtcca aagccaccac atacaaaggg
     6241 tcgggcgacc aaaccatatc ttcgtgtaca tccagccccg tacagtgtcc cgtaaaagcc
     6301 tcaatcgtct cataactctc gtcgccccgt atctgtatac tctccgtatt gaagttatag
     6361 gccaccaccg catacttccc cggcggtacc ttcacctcac cccctccggc aggcagataa
     6421 ctttcaacct ttctcccctg agtatctttc ggatagaaga taatccgcat ggtctgcggc
     6481 agcttatccg tcaccccttt ccaatccagt ttaatctgta ctccgctaac gggataatca
     6541 tccagcatat cgcggaagtc acagcttccc agcattggca acagtccgaa gaacagccag
     6601 agaatcatat gccgtgcatc tttcatacca ctcatctccc cgacgttaga agccacacca
     6661 aagaaatttt tgcttttgtc ggcccgataa agtgatactt tccactgctg acccaaacca
     6721 agtcatttcc ataagaagta tatttcctgt actccgtatc caagtatcca atgcccacac
     6781 tgaattcaat cgccagatgc cgagccagtg gacgcacgta tccataagtt attcctgcag
     6841 ctgcgtaata cttcccccgg tatcccttct cctttttcaa ctgaaaatca taggtacctc
     6901 cttcggcata tgctcccagg aagtgtccgg acaatcttcc gcgcgtatgg cggtttccca
     6961 accagtaacg cgcctctgtc cctcccgaaa ggagctgata gcagaaatta catccgctgt
     7021 cagaccacca agggcatttg tactcaacat tcaaagacca cctctttccc aatggcagct
     7081 ccacttctat gttcggagcc aaggccaggt cgtaaagcaa attatttttt aacgccagca
     7141 ccgttttaca agtatggcta tgggattcta ccgacttatt ctgccctatt acctgccccg
     7201 acatcatgca aaaaaggagt agccaaaaga catatataaa aatgcgtttt cccataattt
     7261 cgcgttgtat acaaacaaaa gtagaagata attaccgaat aaaaatcact ttccatcact
     7321 cttttcaaag gctgaaaggt tctgtgaaac gattgaaaca gatttgcaac ttctgcctta
     7381 tccgggacgc tgtgaataga ttcttctctc tcaaaaagtc aatccgtgtg cgaaaacagt
     7441 aaaattcagt gaaagaaata caaaagaagt agcaggaaca ttctgaaatt tggaagataa
     7501 caacgggaac cttacatttg taatgtgatt tttttcatag tattagattt aaggttaaca
     7561 aaggttggag tacagcggta ctcctttttt tatgcccata cgtttctccg aatgacaaaa
     7621 aatagctatc ttcgatggct tttataactg ttaaagaaga aaacatcact acttgagccc
     7681 attatgaaaa aaccggtact cacattgctt tccataatcc tacttaccgc aggatgttcc
     7741 caacggcctg ccaccaccaa gataccccta accagcgcac accgtggtgc ggccaccatc
     7801 gctcccgaaa acacaatggc atccgtagat tcgtgcatca aatacggtgt aggcaatata
     7861 gaatgcgatg tctgcatcag taaggacagt gtcttctacg tactgcacga ttccaccctc
     7921 gaccgtacca ccaacggtac cggcgccatc tcccaatggc tgtccaccga catcgacaca
     7981 ctggatgccg gctcttggtt tgcgccccga tttgccggac aacgggtact acgccttacc
     8041 gacctgctac gcaaggccaa agagcacggt ttaagaatca ccatcgacta ccgcaacggc
     8101 ggtctgcacc aattactgga tctgataaag gacgaaggca tgctggaaaa ctgcaacttc
     8161 accttcagca aggagtatca tgccaaatgc ttcagaaaga tggcacccga ggtaagaacc
     8221 ctgcaagcct acatcaaaag tgaaaaggac atagagcatg tcgtaaagga actgcatccc
     8281 gacatcgctg tcgtctggat tgactccctt accccacaat tcgtaaagaa atgccgtgag
     8341 cacaacctgc aggtactggc actcgtcctg gggctggacg acaagacgga agagaaccag
     8401 aaggcagtcg acctgggggt agacatcata gcgacggacc acccggaaaa gttcatcatg
     8461 aaatacggga aaccgtccat ataaggcaag agacctgccg cgctcaagtc agcaagtgat
     8521 agacaccacc caccattgcc ttgaccactc ccttcatctc caattcaaaa agcaaggcac
     8581 tcatccggtt gacgggtatg tccgcttcca ccaccatcgc attgatatgg aggtctccct
     8641 gccgcataag gatgcgcata acaagctcct cctcttctgt cagttccgga aagagattac
     8701 gctgaatacc ttctgtccgg gcaggctgct ccgctacggc ccagcccata atctgcacaa
     8761 actcttccgc actctggata agggcggcct tgttgtcgcg tatcaaccgg ttacaaccga
     8821 tggaagattc gtccgtaaca cgccccggaa cggcaaagca gtcacgatgg tatccctccg
     8881 ccaactctgc agtgataagg gaacctccct ttgcggcaga ctccaccaca atggtagcat
     8941 cactcatacc cgccacaata cggttgcggc tgacgaaatt atgcttgtcc ggattcgtcc
     9001 cggtaaggaa ttcggtcagc agtccgcctt gtgccagcat gtcgatggct gttttccggt
     9061 ggacatacgg atagatgcgg tccagtccgt gagcaaggac agcaacggta gggagatgat
     9121 ttgccaaagc ggcccgatgg gcatggatat ctatcccgta agccagtccg cttactacca
     9181 gcacatcggg acaaagaacg gccaaatcgc gcaggaagtc ggcacagaat tgcttgccgt
     9241 aatcggtggc acggcgtgta cctaccatat cgatgacatg caggcggttg aaatcggtgt
     9301 ttcctttaaa gaaaagtaca atcggcgcat cctcacattc gcgcaagcgg gaagggtaag
     9361 cctcatcctt caacgtcagg caggaaagac gattcttctc tacaaactcc atctcctgct
     9421 cggcacgcag aaaggcagcg ggacaatcaa gagccgtcac tacccccgga ttcacaccgg
     9481 gcatgatttc ggggagctcc ttccgccgac tgaatacttc ggcagcactg cccataccct
     9541 ctattaaacg ctttgccccg atatgtccta taccggggca aagtgtgaga gctatgctgc
     9601 aaatccgttc gtcactgttc attccaccac agattacaca gattcacacg gattgagata
     9661 aggggcaaag agacggtcga acagttcgct atcgcttaac cgtccgttca ccacacatac
     9721 ggtttcaact atgcctttga gacagacttt gccgtcggaa gcacgaaaga tatcttggta
     9781 aaagacgtac ttgataccct ccttcttcat gtagagtttg gagacaaact cgtcaccact
     9841 cctcagggga gtcttgaaag ccatattgat acgtgccact accgggtcta ccccctgctc
     9901 gtgcagtccg gcaaagctga cgccggcact caacagaaac tcatggcgcg tatgctccag
     9961 ataatgctga taattggcat tattgacgat gccttgcagg tcgcattcat agtcgcgcac
    10021 cttcatggga agttcataga tataattcat atttactatt ggactattta ctatttgata
    10081 cttagccacg ttgtttctcc acatccaagc ctttgaactt cttcagttcc tctacgctga
    10141 ccagcttgta gagtttgtca ctgggacgta ttttcaccga tttcatcgag aaatgctggc
    10201 ctttctttac agtctgcacg ggtttcaaat cgacgcgtgc ctcgtccaaa gtgacgaatt
    10261 cggcacccgt tgtgggaccc gtaatcagca acttgtcgcc tacgctcact tcggctgctt
    10321 ctaccaggaa ctctgccaca ccgatgtttg agaagtagcg gatgccctta cccacataga
    10381 ttttacgttc cgtagcggca gagccgtagt tcttggtcca ttcgcccaag cgttgtccca
    10441 ggtagtagcc gtcccagaaa ccacgattga agaccgtctt caaacgttcg tcccaccggg
    10501 caattttctc atcggtgaat gtatcgtcca gataggaacg gatggcttct ttgtaacact
    10561 ccactaccgt gcgcacgtac tcgggtccgc gggcacgtcc ttctattttg aaaacacgaa
    10621 cacctgcatc cagcatcttg ttcatgaagt ggatagtttt taagtctttg ggggacatga
    10681 tgtattggtt gtccacctcc aattccacat ccgtctcctt gtcgcgcacc gtataactac
    10741 ggcggcatac ctgcatgcaa gcaccacggt tggcagagtg gttcatctca tgcaatgaga
    10801 gataacactt tccgctgact gccatgcaaa gggcaccgtg gcagaacatc tctatacgta
    10861 tctgctctcc gctgggtcca cagatattct cctcacggat atggcggtag atttctgcca
    10921 cttgctccag attcaactca cgcgccagca ccaccacatc ggcaaactgc gcatagaagc
    10981 gcagggcttc cacgttgctg atgttgagct gtgtgctgag gtgtacctcc tgccctatct
    11041 gccgggcata actcatcact gccacatcag cggcaatgac tgccgagatg cctgccgcct
    11101 ttgccgcatc tacaatggta cgcatcagcg gaatgtcatg gtcgtatata atggtattga
    11161 cggtgaggta gctcttcatg ccatgttcgt cgcacgtccg ggctatttcc cgcaaatcgt
    11221 cgatagtgaa ggtatttgcc gaacgggcac gcatgttcag gttctcgata ccgaaataga
    11281 tggagtcggc acctgcttgt atggctgctg cgagagattc gcgcgagcct accggtgcca
    11341 tgatttcgaa gtcactgatt gagtgtttca tcatttcttt ttgaattaga gtatgcaaag
    11401 gtaggctttt ttctgtactt ttgcggacaa atccgcttag attatgaaga ttaaagatat
    11461 agacctgggc ccacgccccg tattcctcgc cccgatggag gacgtcaccg accctgcttt
    11521 ccgcctgatg tgcaagcact tcggagcaga catggtatat accgagttcg tttctgccga
    11581 tgccttgata cgctccgtag gcaagaccca gcagaaactg aacatcagcg atgaagagcg
    11641 gcccgtagcc atacagatat acggacggga caccgccacc atggtagaag ccgcccgcat
    11701 tgtggagcag gcacatccgg acacgctgga catcaacttc ggctgccccg tgaagcgcgt
    11761 tgccggcaag ggtgccggtg ccggtatgct acagaacatt ccgctgatgc tggaaatcac
    11821 tcgtgccgtg gtagatgccg tgaagattcc cgtcaccgtg aagacccgcc tgggctggga
    11881 tgccaacagt aaaatcatcg tagaccttgc cgagcagttg caggactgcg gcattgccgt
    11941 cctcaccatc cacggccgta cccgcgccca gatgtatacc ggcgaggcgg actggacact
    12001 tatcggcgag gtgaaaaaga acccacgcat gcacattccc atcatcggca acggtgatat
    12061 caccactccc caacgggcca aagaatgctt cgacctctac ggtgtggacg ccatcatgat
    12121 aggccgtgcc agcttcggcc gcccgtggtt ctttaaggaa gtgaagcatt atttggagac
    12181 gggcgaagaa ctccctccgc tgagttccga atggcggctg aacgtactcc gccaggaagt
    12241 ggaagacagc gtcaacctgc tggatgaacg acggggcata ctgcacgtgc gccgccacct
    12301 ggcagcaagc ccgctcttca aagggattcc caatttccgc gacacccgga tagccatgct
    12361 gcgggcagaa acgaaggagg aactgtaccg catcttcgaa gagatagaac cgttgctgcc
    12421 ataggagaaa accgcatacg atttttacca tcgagtccga cacttgagca atcatcctca
    12481 cgccccttct tgaatagctt ctgagagggg ggctattcag acgcagatga cacgctttgt
    12541 tgccatccgc ataactcact gtctgtcagc aagaaatttt gccaaccact tgccttgccc
    12601 ttggcaaact tttgccatgc ctatggcaaa gttttgccaa cgcggtggca aagccttgcc
    12661 aatgggaagg caaaacctta ccaacaagga ggcaagaaaa aaaacattgt ttctttggca
    12721 gaaagaaaca agtccctata ttcgtcttcc caagaaagaa agaatcccat aaatatgtct
    12781 ttatgaaaaa gaaaaaactg ctcaaacagc tcatcgtaaa cttccagcat tcacttccgg
    12841 cagaagttta tccgcgtaca ttggtattgc ccacagacag tggaaagata atcaccgtgc
    12901 ccgactagcg gaacatcggc tgcgcaaacc atcgcttgaa catccacgtg gccaggatat
    12961 aaatgccgaa agccgatacg aaacccacga tagagtctat caggtaatgt gcctggatat
    13021 agaccgtagc cccgcacaac agcagataga aaggaaacaa gcaggcaaac agacgcttgc
    13081 tgccacgcca tgccataatc atcagtaccg tagacattcc gacatgcgaa ctgggaaaag
    13141 cagccgtggg gcgctcaccc acctgctggg aactctccac caggttgtag aagaagccgt
    13201 gctcatagcc cggaccggga agaagttcct gatggtgatg gaaatagtca ccgatggacg
    13261 gaaagatacc ttgcgccaca tggtcgcttc caatggcggg gaagtagaac tgcggcccgg
    13321 caacggggac gaagatataa ataaggtaat agatgaagaa agcggtgacg atgacgaacg
    13381 aaaccttctc gaaaaggtcg aaacgataaa ggaaatacca caccaccacc agcagaatca
    13441 tcggataata gaagaagtac cccatattaa acggctcgct cacccac
//
