LOCUS       c00018_gnlPro..        13643 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIBBIEJD_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:14:50
            Original ID  :: gnl|Prokka|HIBBIEJD_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 51109
            Orig. end    :: 64752
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13643
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[61109:64667](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13558)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13643
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13643
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             1086..2570
                     /locus_tag="ctg18_45"
                     /transl_table=11
                     /translation="MKIQKMKIPTILGALLVAGTLSAGAQMNSDSLYKEPYRPQYHFSP
                     EKGWIGDPSGFMYYQGKYHMYWWGKVESTDLVHYQQITPYAMTGADDNISYFTGSAVVD
                     KNNTAGFGKGAYVAAYTVFEKDSKKQAQGISFSHDGKTFHYYEGNPVLDLWSTEFRDPT
                     VFWHEPTQKWVMAVAKALEKKIKFYTSPDLKNWTWTSDFGPAGDSEKSWECPDLFQLPV
                     DGNSDKKRWVMVVSVNWAQEQYFIGDFDGTSFKLMENHPAEPLYVDKGLDFYASRTFQD
                     FDGTLDSKISMGWVATWDYAPVAPSRYGKGFWSIPRNLELKTYKEGVRLVQKPVEQLQT
                     LRHKPASVKRALSVGTQRLPGFVPDENVYELDASFSTDVSNTFGLNLCVGEGRKVVVSY
                     DTDSHNLVIDRTHCSDVQIPKFSRMAYARVEPVDNKIHLHIFVDKSSIEIFANDGKDVF
                     TLLTYPGEAQTGIELFAQKKGTKMELDAWMLKSIWR"
     CDS             2707..4521
                     /locus_tag="ctg18_46"
                     /transl_table=11
                     /translation="MIHLKDFWRTIRRTLTVFILGTTVAVFTCQAINPPFVIKHLGDGQ
                     SIVQIDEQKKFLLLPVEEASPEAKLYMIADNDVVRSMNVRLAVNKVDYFVPVDLTGFDN
                     KHLSFNFQLIPDSALCWEEMKLSDEFDVSNREKYRPVYHFSPAYGWMNDPNGMFYKDGV
                     YHLFYQHNPYGSMWGNMHWGHATSTDLVTWEHHGDAISPDALGTIFSGSCVVDKDNTAG
                     FGAGAVIAFYTSASDRQVQSMAYSLDNGKTFKKYARNPILTSTQRDFRDPKVIWHEDTK
                     KWIMVLAVGQEMEIYSSADLKSWTLESKFGEGQGAHGGVWECPDLLELPIEGTELKKWV
                     LVCNLNPGGPFGGSATQYFVGTFDGKRFVNESPAVTKWMDWGKDHYATVTWSNAPAGRA
                     IALAWMSNWQYANDVPTRQYRSANSVPRDLSLYTSEGETYVKVTPSPELLKLRDKGSKK
                     RAFKVDRTYNLDKLLNDNSGTYEIEMTIKNKDADVIGFQFFNSKGEEVEMYYNLAEKTF
                     TMDRTKSGEVSFSKDFPAVTVAPVEGGNEMKLRLFVDKSSIEAFGNDGRFAMTNLVFPS
                     EPYNRISFYAKGGSCNVTSFTVYKLGLK"
     CDS             4540..5706
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 100.2; E-value: 3.8e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_47"
                     /sec_met_domain="MFS_1 (E-value: 3.2e-31, bitscore: 100.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENTKNSSLAKLFPVMLCFFAMGFVDLVGIASNYVKADLNLTDSQ
                     ANIFPSLVFFWFLIFSVPTGMLMNRIGRKKTVLLSLVITFASLLLPVFGDGYVLMLLSF
                     SLLGIGNALMQTSLNPLLSNIVSGERLASSLTFGQFVKAIASFLAPYIAMWGATQAIPS
                     LGMGWRVLFPVYMVIAVIAILWLSGTSIREEKEEGRPSTFGECLALLGKPFIFLCFLGI
                     MCHVGIDVGTNTTAPKILMERLGMTLADAGFATSLYFIFRTAGCFLGAFILQKMAPRTF
                     FGISVLCMLAAMVGLFVFHEKAMIYICIALIGFGNSNIFPVIFSQALLAMPQKKNEVSG
                     LMIMGLFGGTVFPIAMGLASDAVGQSGAVAVMTVGVVYLFFYMLRMKR"
     CDS             complement(5682..5924)
                     /locus_tag="ctg18_48"
                     /transl_table=11
                     /translation="MNDIFYSRQTQCPTHCKPNKKVPNYRMKSCQLSIKKSLRTKDYLY
                     PKAWDRHPQPWDRYPQPWDMCPQPANKDYRFIRSI"
     CDS             5941..6828
                     /locus_tag="ctg18_49"
                     /transl_table=11
                     /translation="MNKIIVGMGEALWDCLPEGKKIGGAPANFAYHASQFGFDSRVVSA
                     VGADADGDEILDVFARKGLRTQIERVPYPTGTVQVTLDAVGVPCYEIKEGVAWDNIPFT
                     DELKRLALNTRAVCFGSLAQRSETSRITINRFLDTMPDAEGQLKIFDINLRQGFYTKEI
                     LCESMRRCNILKINDEELVTISRIFGYPGIDLQDKCWILLAKYNLKMLILTCGTNGSYV
                     FTPGVVSFQETPKVPVADTVGAGDSFTAAFTAAILSGKQVPDAHKLAVEVSAYVCTQSG
                     AMPELPVALKERLA"
     CDS             6894..9659
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_50"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.2e-16, bitscore:
                     51.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKMRQHNLRILFFLLVLWGVAVACSRREARFRIGVSQCSEDEWRR
                     QMNSEILREAHFYEDVEVDIRTAVDDNDRQAKDIRELIAEGVDLLIVAPNEATPITPVV
                     EEAYNRGIPVIVVDRKILSDKYTAYVGADNYEIGKAVGEYVANVLHGQGDVVEISGLVG
                     STPAVDRHQGFVKAISAYPGIRLLAVEDGAWLQLKAGEKMDTLLSRFPHIDLVYAQNDR
                     MAAGAYAAAAREGREKDMRFIGIDALPGKDYGVEKVLAGELDATFIYPTGGDRVMQIAM
                     DILNKRDFPRETILGTSVVDHDNALIMKMQTAHIGTLDGKIETLNGKINQYLASYATQQ
                     VVLYGSLSALLLLVGLLVAVYLSLRAKNRLNRELSMQKKKLEEQKTQLIQQKELLEVQK
                     SQLEQLSHELEEATHAKLVFFTNISHDFRTPLTLIADPIEQLLANRTLDGQPRQLLELM
                     KKNVHILLRLVNQILDFRKVENGRMELHLEPFDLLDSFRGWNDSFRMALLKKHIAFSFE
                     ASPDTDFRMMADAEKMERIYFNLFSNAVKYTPENGKITVRLLKSEQNYSLSVFNSGSYI
                     SSTDVEAIFERFYQVDGHQAGTGIGLALVRAFVEMHGGNITARSDEKGTTFIVTFPQQD
                     VSQYHPTIVTLPAEEKDVSSTLIDTEVKACEEVVEADCPTVLVIDDNADIRNYVKSLLS
                     NEFRVLDAADGTEGIRLAMKYVPDVIISDVMMPGMDGVECCRRLKGELQTCHIPVILLT
                     ACSLDEQRIQGYDGGADSYISKPFNSQLLLSRVRNLIANRRQLRQFFGDNQTIEKETIS
                     DLDKGFVSRFKSLVEERMKDAELNVEDLGRNMGMSRVQLYRKLKSLTNYSPNELLRQMR
                     LKKAASLLASSDMTVAEIAYEVGFSSPSYFTKCYKEQFGESPTEFLKRRG"
     CDS             complement(9722..9910)
                     /locus_tag="ctg18_51"
                     /transl_table=11
                     /translation="MIGFIIWIIGVVLCVKAVLEIMKWPVDGVKKLLVAIIILLTSWIG
                     ICVYYFWGRENLPQILK"
     CDS             complement(10001..13558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_52"
                     /sec_met_domain="PFOR_II (E-value: 9.4e-19, bitscore: 59.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.2e-82, bitscore: 267.0,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3.2e-31, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.3e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.8e-12, bitscore: 38.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.2e-07, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00012, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.3e-25, bitscore: 80.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KARVPFMNFFDGFRTSHEIQKIEMLENEDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGLVAVHLYRPFSAKHFLAAVPKTAKKIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILAVYKNLAMPMPKNHFTIGIVDD
                     VTFTSLPQEEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNITVYYINATQIAQEIGLGNRTNTILQSAFFRITGVIPV
                     DLAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKQLTVDPAWANLADDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWEQGTAKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGANFTQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADV
                     CPGNPKKGGKALTMKHLESQLPEAANWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTKNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKAMEDAIAAEGTPAEYKEVFQAWIENMYDADKSKE
                     LAEKIIPMVEAAKDKCDSCKTIASLSQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQAEEEKAVKCGYWHLWR
                     YNPALEAEGKNPFTLDSKEPDWSGFQDFLKGEVRYASVMKQYPQEADELFKAAEENAKW
                     RYNSYKRLSKENWGAEVTE"
ORIGIN
        1 ttgatagaat gggagaaata tgcgggtaat ccggttattg ccgagaagcc tgccggatat
       61 acccgtacgg acatgcgtga ccagtatgtc tggaaagagg gtgatgtctg gtatatgatt
      121 atcggtttcg gcattgagca gaccgataca ccccacgggg ctttgctgct ttataaatcg
      181 gcagacttga agaaatggga ttttgtacat ttgctgtttg agggcaatcc ggaagtggat
      241 gactccggta ttttctggga aatgccggtc tttaagaaga tgggcggcaa gtatgttctt
      301 ttggtgaata gggttcctca taaaggcata cctgcgcgtt gccagtattg gataggagat
      361 ttcaagaatg aaaagtttat accggacaat ccggttcctc aaaatctaga ggtcatcaac
      421 cgcttgctgt ccccctctgt tgtggagact ccggaagggg atgttgctgc cattgccatt
      481 atacccgatg aaataggagg ggaggccact tatgaacaag gatgggcaca tctctacagt
      541 atgcccagaa gatggcagct gaaagatggg aaactatgcc aaacacccca tcccgtgatg
      601 aaacaattgc gtgaacaacc gacggtttat tccagacagg cattgactgc tgcgaaaccg
      661 tgcattgtga gcagaaggga acatcagctt gaagtcaagg cgacttttta tcccggtgac
      721 gcaaaacggt ttggatttac attgtgtaag aatccggata atagcgaata tagcctgatt
      781 tattatgatg tggagaagga ggaacttatt gtggaccaga cgcattcttc ctcgcgtgca
      841 cacattcctt tgaagattcg taaggactgg tatcggttgg atacaaccaa gccggtggag
      901 attcgtctat ttatagacgg ttctgtggtg gaaggattta ttaatgatga ggatgcattc
      961 actacaagaa tctttcctct gaaagaaaac agtacgctat tggaactatt ctctgatgga
     1021 aatacaacgg aagttgctgc cgaagtttgg agactgaaag atgcaagggt aaagatgaac
     1081 ttttaatgaa aatacagaaa atgaagatac ctactatatt gggtgcactt ttagtggcag
     1141 gaacattgtc tgccggtgca caaatgaatt cagacagttt atacaaagag ccttatcgtc
     1201 ctcagtatca tttcagtccg gagaagggat ggattggtga cccctcggga ttcatgtact
     1261 atcagggtaa atatcatatg tactggtggg gcaaagtcga atctacagat ttggtacatt
     1321 accaacagat aaccccttat gccatgaccg gagcggatga caatatcagt tacttcaccg
     1381 gttctgcagt cgtagacaag aacaacacgg ccggtttcgg caagggtgct tatgtggcgg
     1441 cttacaccgt ttttgagaag gactccaaga aacaagcgca gggcatctct ttcagtcatg
     1501 acggaaagac atttcattat tacgaaggta acccggttct ggacctttgg agtacggaat
     1561 tcagggaccc taccgtcttc tggcacgagc cgacccaaaa atgggtgatg gctgtagcca
     1621 aggccctgga gaagaaaatc aagttttata cctctcctga tttgaagaac tggacttgga
     1681 ccagtgattt cggccctgcc ggtgacagtg aaaagtcttg ggagtgcccg gatttattcc
     1741 agttgccggt tgacgggaat tctgacaaga aaaggtgggt gatggtcgta tctgtaaact
     1801 gggcgcaaga acaatacttt ataggagact tcgacggcac ttcttttaag ctgatggaga
     1861 accatcctgc agagcctcta tatgtggaca aagggctgga cttttatgca tcccgcacat
     1921 ttcaggattt tgacggaacg ttggattcca aaatttcgat gggctgggtt gcaacctggg
     1981 actatgcacc ggtagctcca tcgaggtatg ggaagggctt ctggtctatt ccccgcaacc
     2041 tggaactgaa gacatacaag gaaggtgtga ggctggtaca gaagccggtg gaacagttgc
     2101 aaacacttcg ccataagcct gcgtcggtga aacgtgcttt atcggtggga acacagaggt
     2161 tacccggctt tgttcccgat gagaatgtct acgaactcga tgcttcgttt tctactgacg
     2221 tatccaacac ctttggcttg aatttgtgtg tgggtgaagg gcgcaaagtg gtggtcagct
     2281 atgatacgga ttcacataat ctggtgattg accgtaccca ttgctccgat gtgcagattc
     2341 ctaaattcag ccgtatggca tatgccaggg tggaaccggt agataataag atacatttgc
     2401 atatatttgt agacaaatcg agtattgaaa tctttgccaa tgacgggaag gatgtattca
     2461 cattattaac ctatccgggc gaggctcaaa ccggtatcga actttttgcg cagaagaagg
     2521 ggacgaagat ggagttggat gcctggatgc ttaaatcaat atggagatga ggaatttaat
     2581 ttgtattatt ttagactgaa tgtaacattt gtagtatgct ttgaaacaaa aaagatagcc
     2641 tcctgctgct tggtggcgta tctttgcatg gtagaaaaac ataattaatt taataccaac
     2701 agaaacatga ttcatttaaa agacttttgg cggacaatca gaaggacgct taccgtattt
     2761 atattaggaa ctaccgtggc tgtcttcaca tgccaggcca taaatcctcc tttcgtgatt
     2821 aaacatctgg gtgacggaca gagtatcgtc caaattgacg agcagaagaa gtttttgctg
     2881 ctgccggtgg aagaggcttc tccggaggca aaattgtata tgatagcgga caatgatgtt
     2941 gtacgcagta tgaacgtgcg attggcagtc aataaggttg actattttgt tccggtcgat
     3001 ttgaccggct tcgataataa acatctctct ttcaacttcc agcttattcc ggattcggcc
     3061 ttatgctggg aagaaatgaa actgtcggat gaattcgatg tttcgaaccg ggagaagtac
     3121 cgtccggtgt atcatttcag cccggcttac ggttggatga atgatcctaa cggaatgttc
     3181 tacaaagacg gggtctacca tttgttctac cagcataatc cctacggctc catgtggggg
     3241 aacatgcatt ggggacatgc caccagtacg gacctcgtca cttgggaaca tcacggagat
     3301 gctatttcgc ccgatgcgct gggaacaatt ttcagtggct cttgtgttgt cgacaaggat
     3361 aatacggccg ggttcggtgc cggtgccgtc attgccttct atacatcggc aagcgaccgc
     3421 caagtgcaga gcatggccta tagccttgac aacggaaaga ccttcaagaa gtatgcgcga
     3481 aatcccatcc tgacttccac gcagcgcgac ttccgtgacc ctaaagtcat ctggcacgaa
     3541 gataccaaga aatggatcat ggttcttgcc gtagggcagg aaatggagat atactcttct
     3601 gccgacctga agagctggac gctggagagc aaattcggtg aaggacaagg tgctcacggc
     3661 ggagtctggg agtgtcccga cttacttgaa ctgccaattg aaggtacgga actgaagaag
     3721 tgggtactcg tctgtaacct caatccgggt ggaccgttcg gtggctctgc cacacaatat
     3781 ttcgtgggga catttgacgg aaagagattc gtgaacgagt ctcccgcagt gacgaaatgg
     3841 atggactggg gaaaagacca ttatgcaact gtcacttgga gcaatgctcc tgcaggacgt
     3901 gccattgcat tggcatggat gagcaactgg caatatgcca acgatgtgcc cacccgccaa
     3961 taccgtagtg ccaactccgt gccgcgcgac ctttcgctct atacctcgga gggtgaaacc
     4021 tatgtaaagg taaccccgtc tcccgaattg ctgaaactga gggataaagg cagcaagaag
     4081 cgtgctttca aggtagaccg cacgtataat ctggacaaac tgctgaatga caattccgga
     4141 acgtatgaaa tcgaaatgac catcaagaac aaggatgcgg atgtgatagg attccagttc
     4201 tttaactcga aaggcgagga ggtggagatg tactataacc tggcggaaaa gacgttcacc
     4261 atggaccgta ccaagagtgg tgaggtgtcg ttcagcaagg acttccctgc agtgaccgtg
     4321 gctcctgtcg agggtggcaa tgaaatgaaa ctccgcttgt tcgtagacaa gtcgagcatt
     4381 gaagcgtttg gcaacgacgg acgttttgcc atgacaaatc ttgtattccc gtcggaacct
     4441 tacaaccgca tcagtttcta tgctaaaggt ggaagctgca atgtcacctc gtttactgtg
     4501 tacaaactcg gattaaaata acagataata atcttcagca tggaaaatac taagaattct
     4561 tccttggcaa agctctttcc ggtcatgctt tgcttcttcg ccatgggctt tgtggatttg
     4621 gtgggcatcg cctccaacta cgtgaaggcc gacttgaacc tgaccgactc gcaagccaac
     4681 atattcccgt ctctggtgtt cttctggttc ctcatcttct ccgtacctac gggtatgctg
     4741 atgaaccgca tcggacgcaa gaagacggtg cttctcagcc ttgtcatcac gtttgcctct
     4801 ttgcttctcc cggttttcgg agacggctac gtgctgatgc tgctctcgtt ctcattgctg
     4861 ggcatcggca atgcgctgat gcaaacgtcg ctcaacccgc tgctttccaa tatcgtaagc
     4921 ggcgagcggc tggcaagttc gctcaccttc ggacagtttg taaaagccat tgcttcgttt
     4981 ctggctccat acatcgccat gtggggagct acgcaggcca ttccgtctct gggcatgggc
     5041 tggagggtgc tgttcccggt ctatatggtc attgcggtga ttgccattct ctggctgagc
     5101 ggtacttcca tccgcgagga aaaggaagag ggacgccctt ccaccttcgg ggagtgcctc
     5161 gctctgctgg gcaagccgtt tatctttctc tgcttcctgg gcatcatgtg ccatgtgggc
     5221 attgatgtag gtacgaatac cacagcgccc aaaatcctga tggagcgtct gggcatgacg
     5281 ctggccgatg ccggctttgc caccagcctt tacttcatct tccgcacggc gggttgcttt
     5341 ctcggagcct tcatccttca gaagatggct ccccgaacct tcttcggcat cagcgtgtta
     5401 tgtatgttgg ctgcgatggt agggttgttc gttttccatg aaaaggcaat gatatacatc
     5461 tgcattgccc ttatcggttt cggcaattcg aacatctttc cggttatctt ctcccaagcg
     5521 ttgcttgcta tgccacaaaa gaagaacgag gtttccggct tgatgattat ggggctcttc
     5581 ggcggtacgg tatttccgat agcaatgggc ttggcaagtg atgctgtagg acaaagcggt
     5641 gccgtggctg taatgacggt gggggtagtg tacttgttct tctatatgct gcgtatgaag
     5701 cggtaatctt tgttcgcagg ctgcggacac atatcccaag gctgcggata tctgtcccaa
     5761 ggttgcggat gtctatccca agccttggga tagagataat ccttagttct tagagacttt
     5821 ttaatagata attggcaact tttcattcta tagttaggaa cttttttatt aggtttgcag
     5881 tgggtaggac attgagtttg ccgtgaataa aatatatcat tcattaaaca atataatatt
     5941 atgaataaga taatagtagg tatgggcgag gctctgtggg actgcctccc cgaaggaaag
     6001 aagataggcg gtgctccggc aaactttgct taccatgcat cgcagtttgg tttcgacagc
     6061 cgtgtggtca gtgccgtagg tgccgatgcg gatggggacg agattctgga tgtgttcgcc
     6121 cggaaggggc tgcgcacgca gattgagcgc gtgccttacc ccacgggaac ggtgcaggtg
     6181 acgctcgatg ccgtgggcgt gccgtgctat gagataaaag aaggcgtggc ctgggacaac
     6241 attcccttta ccgacgaact gaagcgtctg gcactgaaca cgcgtgccgt atgtttcggc
     6301 tctttggcgc aacgcagtga aacaagccgc atcaccatca accgttttct cgacacgatg
     6361 cccgatgcgg aggggcaact gaagatattc gacatcaatc tccgccaagg gttctatacc
     6421 aaagagatac tctgcgaatc catgcgccgc tgcaacatcc tcaagataaa cgatgaggag
     6481 ctggtgacca tcagccgtat tttcggctac ccgggcatcg acttgcagga caaatgctgg
     6541 attctgctgg ctaaatataa cctgaaaatg cttatcttga cttgtggaac gaacggcagc
     6601 tatgtgttca ctccgggagt ggtttccttc caggagacgc ccaaggtacc ggtggcggac
     6661 accgttggag ccggtgactc gttcacggca gccttcaccg ctgccattct cagcgggaag
     6721 caggtgcccg atgcccataa actggcggtg gaagtctctg cctatgtatg tacccagagc
     6781 ggtgccatgc cggaattgcc ggtggccttg aaagaaaggc tggcatagat ttttcttatt
     6841 cttttcacat ttttcgttat ctttgctcat ctgcaatctt aaatcagagg aaagtgaaga
     6901 tgagacagca taaccttcgg attttattct ttctgctcgt gctttgggga gtggcggttg
     6961 cctgctcccg gcgcgaggca cgtttccgta tcggcgtttc ccaatgtagc gaggatgaat
     7021 ggcggcgcca gatgaacagt gagatactcc gtgaagccca tttctacgag gatgtggagg
     7081 tggacatccg tactgccgtc gacgataatg accgtcaggc aaaagatatt cgtgaactga
     7141 tagccgaagg ggtggacctg ctgattgtgg cccctaatga agccactccg ataactccgg
     7201 ttgtggagga ggcatacaac cggggcattc cggtgattgt agtggaccgt aaaatccttt
     7261 cggacaaata cacggcctac gtcggtgcag acaactacga gatagggaaa gctgtgggag
     7321 agtatgtggc caatgtgctg catgggcagg gagatgtggt ggaaatctca ggtttggtgg
     7381 gctccacacc tgccgtagac cgtcatcaag gatttgtgaa ggctatatcc gcttatcccg
     7441 gtatccggtt gctggccgtt gaagacggtg cctggttgca actcaaggcc ggagagaaaa
     7501 tggataccct gctgagccgc tttccgcata tcgacctggt gtatgctcag aatgaccgta
     7561 tggcggccgg agcctatgct gccgctgccc gagaggggcg ggaaaaggat atgcggttca
     7621 tcggcataga tgccctgccc ggcaaggact atggagtgga gaaagtgctt gccggcgaac
     7681 tggatgccac gtttatatat cctaccggtg gcgaccgcgt gatgcagatt gccatggata
     7741 ttctgaacaa gcgtgatttc ccccgtgaaa ctatcctggg cacttccgtc gtcgaccacg
     7801 acaatgctct catcatgaag atgcagaccg cccacatcgg caccctggat ggaaagatag
     7861 aaaccctgaa cggaaagata aaccagtatt tggccagtta tgccacgcag caggttgtct
     7921 tgtacggcag tctgtctgcc ctattgttgc tggtcggttt gttggtggct gtctacctct
     7981 ccttgcgtgc caagaaccgg ttgaaccgtg agctgtccat gcagaaaaag aaactggaag
     8041 aacagaaaac tcagttgata cagcagaagg aactgttgga agtgcagaag tcgcagttgg
     8101 aacagctttc ccatgaactg gaggaggcta cgcacgccaa gctggtgttc ttcacgaata
     8161 tttcacacga tttccgtact ccgctgacgc tgatagccga tcccatagag cagcttcttg
     8221 ccaaccgcac cctcgacgga cagccgcgcc agctcctcga gctgatgaaa aagaatgtac
     8281 atatcctgct tcgcctggtc aaccagatac ttgatttccg gaaggtggag aacgggcgca
     8341 tggagctcca tctcgaacct tttgatttgc tcgacagctt ccggggctgg aacgactctt
     8401 tccgcatggc gttgctgaag aaacatattg ctttcagctt tgaggcatct cccgatacgg
     8461 acttccggat gatggcggat gcggagaaga tggagcgcat ttacttcaat ctcttctcca
     8521 atgccgtgaa gtatacgccg gagaacggga aaatcaccgt acggttgtta aagtcggaac
     8581 agaactacag tctgtccgtc ttcaattccg gcagctacat ttcttcgacc gatgtggaag
     8641 ccatcttcga gcgcttctat caagtggacg ggcatcaagc cggtaccggt atcggactgg
     8701 cgctggtacg tgcctttgta gagatgcatg gcggtaacat tacggcacgc agtgacgaga
     8761 aaggcactac tttcatcgtt actttcccgc agcaggatgt ttcgcagtac catcccacca
     8821 tagtgacgtt gcctgccgaa gagaaggacg tgtcgtccac cctgatagat acggaagtga
     8881 aggcatgcga agaggtggtt gaggctgatt gtcctactgt gctggtaatt gacgataatg
     8941 cggatattcg caactatgtg aagtctcttc tgtcgaacga gttccgtgta ttggatgctg
     9001 cggacgggac agagggtatc cggctggcca tgaagtatgt gccggatgtg attatctccg
     9061 atgtaatgat gcccggtatg gatggtgtgg aatgctgccg ccgcttgaag ggggagttgc
     9121 agacatgcca tatcccggtg attctgctga cggcctgctc gctggacgaa cagcgtatcc
     9181 agggctatga tggcggtgcc gattcttata tttccaaacc attcaattcg cagttgctct
     9241 tgtctcgtgt ccgcaatctt attgcaaacc gccgtcagtt gaggcagttc ttcggagata
     9301 accagactat tgagaaggaa accatcagtg atttggataa gggtttcgtc tcccgcttca
     9361 aatcgcttgt cgaggagagg atgaaagatg cggaactcaa tgtggaggat ttgggacgga
     9421 atatgggtat gagccgtgtg cagctttacc gtaagctgaa atcgctgacc aactattcgc
     9481 cgaatgagct gctgcgccag atgaggttga aaaaggctgc ctcactgctt gcctcctctg
     9541 acatgacggt agcggagatt gcctatgaag tgggcttttc gtcaccttcc tatttcacga
     9601 aatgctataa ggaacagttt ggggagagtc ctaccgagtt tctgaaaaga aggggatagc
     9661 tgttgtctat cccccttgtt cttaatacac gtctgtttac ttctgtaaat gatactggaa
     9721 cttatttcag tatttgaggc aggttttccc ttccccagaa gtagtaaaca cagattccaa
     9781 tccagcttgt gaggaggatg ataattgcaa ctaatagttt cttcacgccg tctaccggcc
     9841 acttcatgat ttcaagtacg gctttgacac acagaaccac accgataatc caaatgataa
     9901 atccaatcat aacctgtgat atttagtatt gttaattaaa aacaaataga gactacgcct
     9961 tattcaggag cagcctctat tctttattta gtaatcggaa ttactctgta acttcagcgc
    10021 cccaattttc tttggaaaga cgcttgtagc tgttgtaacg ccatttagcg ttttcttcag
    10081 cagccttgaa cagctcgtcg gcctcctgcg gatattgctt cattacggat gcgtaacgaa
    10141 cttcaccctt caggaagtct tggaatccgc tccaatccgg ttccttgcta tccagcgtga
    10201 acggattctt gccttcagcc tccagagccg ggttgtaacg ccacaagtgc cagtaaccgc
    10261 acttaacggc cttttcttcc tctgcctggc tcttgcccat acctgccttc agaccgtggt
    10321 tgatacacgg agcgtaagcg atgatgagtg acggaccggg atatgcttct gcttcacgga
    10381 tagccttcag ggtctgagcc tggtcggcac ccatagcgat ttgggcaacg tatacgtaac
    10441 cgtaagtagt agccatcaga ccgaggtctt tcttgcgtac acgcttaccg gcagcggcaa
    10501 acttggcgat agcgcctacc ggagtagcct tggaagactg accgcctgtg ttggagtaaa
    10561 cctcagtatc cagtacgagg atgttgacat ccttaccgct tgcgattaca tggtcgagac
    10621 caccgtaacc gatgtcgtaa gaggcaccgt cgccaccgat aatccactgg ctgcgtttta
    10681 ccaggtattg agacagactg gcgatagtct tgcagctgtc gcacttgtct ttggcagctt
    10741 ctaccatcgg aataatcttt tcagccagtt ccttgctctt gtctgcatcg tacatgtttt
    10801 caatccaagc ctggaatact tctttgtatt cggccggagt tccttctgct gcgatggcat
    10861 cttccatagc cttcacgata cgtgcgcgca tcttttcgtt ggcaagctcc atacccagac
    10921 cgaattcgca gaagtcctcg aacaatgagt ttgcccaagc aggaccgtga cctttttcgt
    10981 tcttggtata aggagtagaa ggtactgaac cggagtagat ggaagaacat cctgttgcgt
    11041 tggctaccat ttcgcggtca ccgaacaact gggaaatcag cttcacatac ggagtttcac
    11101 cacaaccgga gcaagcacct gagaactcga acaacggagt ggcgaactga gagttcttca
    11161 cgttggcctt gatgtcaacc aagtgttgtt tgctcttcac gttttcagca cagtaagtcc
    11221 agttggcagc ttccggcaat tggctttcga ggtgcttcat agtcagagcc ttgccaccct
    11281 tcttcgggtt gcccggacag acatcggcac agttgccaca acccagacag tcgagaacgt
    11341 ctacctgaat acggaatgtc ataccgtcga atgctttacc tacagccttc agttgagtga
    11401 agttggcacc cttctgctct tcagcatcga gtacgaacgg acggatggaa gcgtgaggac
    11461 aaacgtaagc acacttgtta cactggatac agttctcagc gttccattcg ggaacgaatg
    11521 cggctacacc acgtttctca tatttggcag taccttgttc ccaagtaccg tcttcgatac
    11581 ccttgaatgc ggataccggc aataagtcac cgtcttgtgc gttgatagga cgaaccactt
    11641 cgttgatgaa tgcaggatcg ttgttttcag ccttggcgtc gtctgccaga ttggcccaag
    11701 ccgggtcaac ggtcagttgc ttgtattcgc cgccacggtc aactgctgcg tagttcttgt
    11761 tgacaacgtc ttcacccttc tttccgtaag acttaacgat gaatttcttc atctgttcta
    11821 cagccaggtc aaccggaata acgccggtga tacggaagaa tgcggattgc aggatggtgt
    11881 tggtacggtt gcccaaaccg atttcttgtg caatctgagt agcgttgata tagtaaacag
    11941 tgatattgtt ctgtgcaaag tacttcttca ccttgttggg caggttcttg gcaagctctt
    12001 cgccttccca gatggtgttc agcaagaaag agccgttctt acgcaagccg cgggttacgt
    12061 cgtacatgtg caggtaagcc tgaacgtggc aagccacgaa attaggcgta tttaccaggt
    12121 atgtagagcg gataggagtg tcgccgaaac gcaggtgcga gcaagtgaaa ccgcctgatt
    12181 tcttggagtc gtaagagaag taggcctggc agtgcttgtc ggtgttgtca ccgataatct
    12241 tcacggagtt cttgttggca cctactgtac cgtcagcgcc cagaccgtag aatttggctt
    12301 cgaacatgcc ttcgccgccc aatgcgattt cttcttcctg gggaagagaa gtgaaggtaa
    12361 cgtcgtccac gataccgata gtgaagtggt tcttcggcat cggcatagcc agattcttgt
    12421 aaacggcgag gatttgagca ggagtagtat ccttggaacc caaaccatag cggccgccta
    12481 cgataaccgg agcattctct gcaccgtaga agcagtcttt tacgtcgagg tacaacggtt
    12541 cgccgttagc acccggttct ttcgtacggt ccagtacggc aatcttcttg gcagtcttgg
    12601 gaacggcggc aaggaagtgc ttggcagaga acggacgata caagtgaacg gcaaccaaac
    12661 ctaccttttc gccattggca acgaggtggt cgatagcttc gcgggcagct tccgttacag
    12721 aacccatggc gatgataacg cgttctgcat cttctgcacc gtagtaatcg aacaaaccgt
    12781 acttgcggcc tgtgattttg gaaatctcgt tcatgtattc ctcaacgata gccggaactg
    12841 cttcatagta gttgttgcaa gattcacggt gttggaagaa gtggtcagga ttttcggcca
    12901 taccacgggc aaccgggttc atcgggttca atgcacgtgc gcggaattca gccaaagctt
    12961 cctggtcgat aagcggagcg aggtcttcgt tctccagcat ctcaatcttc tggatttcgt
    13021 gagaagtacg gaaaccgtcg aagaagttca taaacggaac acgggccttg atggtggcca
    13081 ggtgggcaac acctgccaag tccataactt cttgtacaga accttcggcc aacatggcga
    13141 aaccggtctg gcgtgcagac ataacgtcct gatggtcgcc gaagatacac agtgcatggc
    13201 ttgccaatgt acgtgctgat acgtggaata cacaaggcag gaattcaccg gcaatcttgt
    13261 acatgttcgg gatcatcagc aacagacctt gtgaagctgt gtaagtagta gtcagcgcac
    13321 cggcttgcag agagccgtga acggcacctg cagcaccgcc ttctgactgc atttcctgta
    13381 ccaatactgt ttcgccgaag atgttcttgc gacctgcggc agcccattcg tctacgtatt
    13441 cagccatcgt agaagagggg gtgatggggt agatggcagc tacttcggag aacatatacg
    13501 agatatgtgc agcagcctgg ttaccatcac aagtaatgaa tttcttctgt ttagtcataa
    13561 ctaaattgaa tttattaagt aaaaaaatct ctttgtctgt aaatcctaat acaggaaacc
    13621 gaacaaccag agcggtattt gat
//
