LOCUS       c00031_gnlPro..        15157 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIBBIEJD_31.
ACCESSION   c00031_gnlPro..
VERSION     c00031_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 22:14:50
            Original ID  :: gnl|Prokka|HIBBIEJD_31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 29459
            Orig. end    :: 44616
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15157
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[39459:43734]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14275
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..15157
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15157
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1492..2046)
                     /locus_tag="ctg31_27"
                     /transl_table=11
                     /translation="MEKSKDTWTVLSSEYLHRAPWLTVRKDHVVLPNGNHIPSYYILEY
                     PNWVNTIAITRDGQFVFIRQYRHGIQETSYELCAGVCEEEDGSPMVSAQRELLEETGYG
                     NGVWKEFMQISPNPSTHTNITYCFLATDVEKISEQHLEDTENLTVHLLSLQEVKDLLQQ
                     GSIRQALMAAPLWKYMAERII"
     CDS             complement(2061..3140)
                     /locus_tag="ctg31_28"
                     /transl_table=11
                     /translation="MKDFQIQAIGLMSGTSLDGLDVCCCTFRQQAGKWSFHIDCAKGYS
                     YPDAMKQILGTGAQTMSALEFITFHSSYGKFLGERVNEFMQEFGVHPDIIASHGHTIFH
                     EPQKRIMYQIGDGAAIAAETRIPTVSDFRRLDIMLGGQGAPLVPIGDRLLFADYDFCLN
                     IGGFSNISFEQDGRRIAFDISPVNYVINHYCRQIGLEFDRDGEIARQGNICQELLDELN
                     GMDFYHQSGPKSLGREWVETLVYPMLERYGLSMENMLRTFYEHAAWQISRIITARPLPD
                     GNGKLLITGGGAFNKFLIERIDALCPCEIVIPSRQIIEYKEALIFAFLGALYMADTPGC
                     LASVTGATTDNIGGMLFKI"
     CDS             complement(3156..4511)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M20"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_29"
                     /sec_met_domain="Peptidase_M20 (E-value: 5.9e-38, bitscore:
                     122.0, seeds: 360, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIKKYITENEPKMLEDLFSLIRIPSISAKPEHHDDMLACAERWA
                     QLLLEAGADEALVMPSKGNPIVFGQKIVDPDAKTVLVYAHYDVMPAEPLELWKSDPFEP
                     EIRDGHIWARGADDDKGQSFIQVKAFEYLVRNELLQTNVKFIFEGEEEIGSPSLESFCQ
                     EHKELLKADVILVSDTSMLGADLPSLTTGLRGLAYWEIEVTGPNRDLHSGHFGGAVANP
                     INVLCQIISQVTDAEGRITVPGFYDDVEEVPQAERDMIARIPFDEEKYKKAIHVKALFG
                     EKGYSTLERNSCRPSFDVCGIWGGYTGEGSKTVLPSKAYAKVSCRLVPHQDHHKISRLF
                     ADYILDIAPDSVQVKVTPMHGGQGYVCPITLPAYQAAEKGFEKAFGKKPLAVRRGGSIP
                     IISTFEQVLGIKTVLMGFGLESNAIHSPNENIPLDIFRKGIEAVVEFYLNYK"
     CDS             complement(4521..5525)
                     /locus_tag="ctg31_30"
                     /transl_table=11
                     /translation="VIDGFPAGIVIDMDFVQAELDRRRPGQSRITTARKEGDKVEFLSG
                     IFEGKSTGCPIGFIVWNQNQHSDDYNNLKEVYRPSHADYTYKVKYGIRDHRGGGRSSAR
                     ETISRVVAGALAKLALKQLGIYITAYTSQVGPIRLEENYTAYDLDLIETNPVRCPDPAK
                     AKEMEELIFKIKGEGDTIGGVVTCVVKGCPIGLGQPVFGKLHAALGAAMLSINAAKAFE
                     YGDGFKGLKQKGSEQNDVFYNNNGRIETRTNHSGGIQGGISNGQDIYFRVAFKPVATVL
                     MEQHTVNIDGVDTTLKARGRHDPCVLPRAVPIVEAMTAMTLLDYYLIDRTTQL"
     CDS             complement(5616..5714)
                     /locus_tag="ctg31_31"
                     /transl_table=11
                     /translation="MLFIQTNPKKSCYLYKVKSIFIREILAHEPHI"
     CDS             6254..7450
                     /locus_tag="ctg31_32"
                     /transl_table=11
                     /translation="MKKNLFYLFALICSMSLFTACSDDDDEVKSLPEVNASYVSSELEL
                     TYGGEVLLGKKVTFNTADGKSADITLEGADIALTKETMASGLVNPGVIPGEPKVTFSAA
                     LQPAESGYTFAGEHVADNYSMKYEGAVEKGKLNLALEVKLAGDNALAGNTWNLFSYDPY
                     AEKNPLHVVWNSEKPFSVVLVPFPGAQPVELQPGAFITLMSAMGIIPVGDKKMGVNEIL
                     SCLLQSVTFREDGNIVASYSDVADIVSPKFQNSPLNMVQYAVKNEKLYLYLNVDAIIGA
                     VQKMTTKGLDMETVIPVVLPKLMELIPMLSSGIPLGYSVNEEGNELAVYIDKELGSKLI
                     DILLSLLENEEIVAAIKEAATSNPDFAMFAGVVEAILEQAPEVFAKTNEMELGLNFVK"
     CDS             7587..8867
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_33"
                     /sec_met_domain="SDH_alpha (E-value: 3.5e-61, bitscore:
                     198.4, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETERQQIISLVKREVIPAIGCTEPIAVALCVAKAAEVLNKRPE
                     KVTVLLSANILKNAMGVGIPGTGMIGLPIAVALGALIGKSEYQLEVLKDSTPEAMEAGK
                     RFIDEKRIHISLKNDIEEKLYIEVCCEAGGDKATAIIAGGHTTFIYVARNSEVLLNKQA
                     VASTEAEGNTLDLSLRKVYDFALTAPLDEIRFILETARLNKAAAERSFEGNYGHGLGKI
                     LRGTYEHRVMGDSVFSHILSYTSGACDARMAGAMIPVMSNSGSGNQGISATLPVLIYAE
                     ENGKSEEEIVRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGAYEQVS
                     YAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAIMAMENRCVTSVEGIIDEDVDQ
                     SIRNLTKIGSKGMNETDKLVLEIMTSK"
     CDS             complement(8975..9547)
                     /locus_tag="ctg31_34"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDVVVMDMNHPLAGCDLNFTGEVVESRPATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             complement(9745..9849)
                     /locus_tag="ctg31_35"
                     /transl_table=11
                     /translation="LFQTCCKGKGFFIISKQIEEKNKINMNNRKKMSP"
     CDS             10001..11839
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_36"
                     /sec_met_domain="ILVD_EDD (E-value: 1e-219, bitscore:
                     721.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGEAFSLKGDLKMKHQLRSSFSTQGRRMAGARALWTANGMKKEQM
                     GKPIIAIVNSFTQFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGML
                     YSLPSRDIIADSVEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEA
                     GEWNGQHLDLIDAMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGL
                     ALPGNGTIVATHENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLD
                     IAMGGSTNTVLHLLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGG
                     IIAIMDELAKGGLVDTNVHRVDGMTLAEAIDRYSITSSDVCKEAIKKYSSAAAGKFNLV
                     LGSQNASYKELDTDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKF
                     TGPAKVFDSQDAACDGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKE
                     CALITDGRFSGGTSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELA
                     ARPMTPVTRNREVSKALKAYASMVSSADKGAVRLID"
     CDS             11931..13682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_37"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-47, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRQAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTDHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     ESTHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             13676..14275
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_38"
                     /sec_met_domain="ALS_ss_C (E-value: 2.8e-19, bitscore:
                     60.6, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKSYEIKEFTLSMDKKLYTIIVHSENFAGLLNQVTAVFTRRQIN
                     IESLNVSASSIKGVHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIAL
                     YKITTPTLEEKPEVSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQ
                     FVRSGRVAITTSCFERVNEYLADREAKYRQSKHQES"
     CDS             14272..15024
                     /locus_tag="ctg31_39"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVATL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVMFTEK"
     CDS             15075..15155
                     /locus_tag="ctg31_40"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREI"
ORIGIN
        1 actggtattg gaagccgaga agcagaaaga ggctatagct gccgggaaga aacctaaaaa
       61 agaagaagag aatcggggta tcgaccccat taccgaccgc gaacgtgggc ttgttttatt
      121 ggaccagatt aagaattctc tttttaccgt gacggatgtc accaagaaag aggggaggga
      181 ggcgccactc cgcttgtttg acttgacttc tttgcaagtg gaatgtaaca agaagtttgc
      241 ctattccgct gatgagacgc tgaaaatcat ccagtctttg tatgagaaga aagtggctac
      301 ctatccacgt gtagacacta cctatttgag tgatgacatc tatcccaaat gccccggcat
      361 cttgaaaggt ctgcgtgatt acgagacatt tacagcccct ttgacaggaa ctgcattgtt
      421 gaagtccaaa aaggttttcg ataactcgaa ggtaacagac caccacgcca ttattcctac
      481 cggccagcat ccgcagaatc tgacggatat ggagcgtcgc gtattcgatt tgatagcacg
      541 ccgtttcatt gctgtattct atcccgattg taagtttgcc actaccaccg tattgggcga
      601 ggtagagagc atagagttca aggccaccgg caagcagatt ctggaaccgg gttggcgtat
      661 tatcttcggc accccctcgg cacaatcgca ggaggagaaa gaggagaagg gagaagagga
      721 gaatgtgctt ccggcttttg tgaaaggaga aagcggaccg cacgtccccg atttgtatga
      781 gaagtggacg cagccgcccc ggccttatac ggaagccacc ctgctgcgtg ctatggaaac
      841 ggcgggcaag ctggtggata acgacgaact gcgtgatgcg ctgaaggaaa acggtatcgg
      901 tcgtccatct acccgtgcag ccatcatcga gacgctgttc aagcgaaact atatccgcaa
      961 ggaaaagaag aacctgatag ccacccctac cggtgtggag ctgatacaga ttatccatga
     1021 ggagctgttg aagtcggcgg aactgaccgg tatctgggag aaaaagctac gtgagataga
     1081 aaggcggaca tataatgccg gacaattctt ggaagaattg aagcagatgg tatcggaagt
     1141 cgtgatgagt gtactttctg ataacagcaa ccgccacatc accatccaag cgcctgctcc
     1201 cgaaaagggc agtaaggttt ctgccaagac agaggctgcc gataagccga aaaaggagcc
     1261 gaagaaaaga acaccgagaa agtctgccgc cgcaggtaaa aagacggagc aggcttcggg
     1321 cgctgtggca gcttcaagta cggaggcttc cgtacaagct gatgacttcg tcggccagcc
     1381 ttgtccgctt tgcggaaaag gtaccgttat caaggggaaa acggcttacg gttgttccga
     1441 atggaaatcc ggatgtacat tccgcaagcc gtttgaataa gggtaatcac attaaataat
     1501 tctctccgcc atgtatttcc agaggggagc agccatcagc gcctggcgga tgcttccttg
     1561 ttgcagcaag tccttgacct cctgcaagga aagcaggtgt acggtcaggt tctccgtatc
     1621 ttccaagtgt tgctcggaga ttttctccac gtccgtagcc aggaaacagt aggtaatgtt
     1681 ggtgtgggta cttggattgg gagagatttg catgaactct ttccatactc cgtttccata
     1741 gccggtttct tccaaaagtt cccgttgtgc ggaaaccatc ggagagccgt cctcttcttc
     1801 gcatacccct gcacagagct cataggacgt ttcttgtatg ccatgccggt attggcggat
     1861 aaagacaaat tgtccatcac gggtgatggc aatggtattc acccagttgg gatattccaa
     1921 tatataatag gaggggatgt ggttgccgtt gggtagcact acatggtcct tacgcacagt
     1981 gagccacgga gcccgatgaa ggtattcgct ggataagaca gtccaggtgt cttttgattt
     2041 ttccataatg gtaaaattga ctatatttta aacagcatcc ctccgatatt atctgtcgtg
     2101 gctcccgtca ccgaggcgag gcatccgggt gtgtccgcca tatagagggc acccaggaaa
     2161 gcaaagatta gggcttcctt gtattctatg atttgccggc tgggaatcac gatttcacac
     2221 ggacacaagg cgtcgatacg ttctatgagg aacttgttga atgcacctcc gccggtaatc
     2281 agcagttttc cgttaccatc gggcaagggg cgggcggtga tgatgcgtga tatttgccag
     2341 gcggcatgct cgtaaaaggt acgtagcata ttctccatac tcaagccata acgctcgagc
     2401 atgggatata ctagcgtttc cacccactcc cgtcccaatg acttcggtcc ggactgatgg
     2461 tagaaatcca ttccgttcag ttcgtccagc agttcttggc agatgttgcc ttgccgtgct
     2521 atctcgccgt cacggtcaaa ttccaatcct atttgccggc agtaatggtt gatgacgtaa
     2581 ttcaccggac tgatgtcaaa agcgatgcgc cgcccatcct gctcgaatga gatgttggag
     2641 aaaccgccga tattcaaaca gaagtcgtag tcggcaaaaa gcaaccggtc gccaataggt
     2701 acgagtggag cgccctgccc acccagcatg atgtccagcc gccggaaatc cgaaacggta
     2761 ggtatacggg tttcagcggc aatggcggct ccgtcaccta tttggtacat gattctcttt
     2821 tgaggctcat ggaagatggt atgcccgtgg gaagcgataa tatcggggtg gactccaaat
     2881 tcttgcatga actcgttgac acgttcaccg agaaactttc cataggagct gtggaaagtg
     2941 atgaactcca aagcactcat tgtctgtgca ccggtaccca atatctgctt catggcgtcg
     3001 gggtagctat agccttttgc acagtctatg tggaaagacc attttccggc ttgctgccgg
     3061 aaagtgcaac aacatacgtc cagcccgtca agggaagtgc cagacatcag gccgatggct
     3121 tgaatttgga agtctttcat cctgattttc ttgttttatt tataattgag gtagaattca
     3181 acaacagctt ctattccttt acggaagatg tccaacggta tattctcatt aggtgagtgg
     3241 atggcgttgg attcgagccc gaagcccatc agaacggttt tgatgcccag tacttgctcg
     3301 aaagtggaga tgatggggat acttccaccc cgacgcactg ccagcggttt ctttccaaaa
     3361 gctttttcaa aacctttttc ggcggcttgg taggcgggta gggtgatggg acatacatat
     3421 ccttggcctc catgcatcgg agtgactttt acctgtactg aatccggcgc tatgtccaga
     3481 atgtagtcgg caaagagccg ggatatcttg tggtggtcct ggtggggaac caaccggcag
     3541 gataccttgg cgtatgcttt ggatgggagc acggtcttgg acccttcacc cgtatatccg
     3601 ccccagatgc cgcatacgtc gaaagacgga cggcaactgt tacgttccag cgtactgtaa
     3661 cctttctctc cgaaaagtgc ttttacatgg atagcctttt tgtatttctc ttcgtcgaaa
     3721 ggaatgcggg ctatcatgtc gcgctcggct tggggaactt cttccacatc gtcatagaag
     3781 cccggtacgg tgatacgtcc ctctgcgtcc gtcacttggc tgattatctg gcaaagcaca
     3841 ttgatggggt tggcaacagc accgccgaag tgaccgctgt gcaggtcgcg gttggggccg
     3901 gtcacttcta tttcccaata ggccagtccg cgcagtccgg tggtcagtga aggcaggtct
     3961 gcaccaagca tgctggtgtc cgaaaccaga atgacgtctg ctttcagcaa ctctttgtgc
     4021 tcctggcaga agctttctaa gctgggcgaa ccgatttctt cttctccttc gaagatgaat
     4081 tttacgttgg tttgcagcag ttcgttgcgt acgaggtatt caaacgcttt cacttgtatg
     4141 aaagattgcc ctttgtcatc atcagcacca cgtgcccaga tatgtccgtc gcgtatttcc
     4201 ggctcaaagg ggtcgctttt ccaaagttcg agaggttcgg ctggcatcac gtcgtagtgg
     4261 gcatatacca atacggtctt ggcgtccggg tctacgattt tctgtccaaa aacaatcggg
     4321 ttacctttgg agggcattac gagggcttca tccgctccgg cttcgagcag caactgtgcc
     4381 cagcgttcgg cgcaggcaag catatcgtcg tgatgctcgg gtttggcact gatgcttgga
     4441 atgcgaatga ggctgaacaa gtcttccagc attttaggct cgttctcggt gatgtatttc
     4501 tttatttcca tgggtgaata ttatagttgt gttgttctgt caatcaggta ataatccaac
     4561 aatgtcattg ctgtcattgc ttccacgatg ggtactgcgc gtggcaatac gcacgggtca
     4621 tggcgtcctc gggctttcag ggtggtgtct acaccgtcaa tgttcacggt gtgttgctcc
     4681 atcagtacgg ttgccacggg tttgaaggct acacggaaat agatgtcttg cccgttactg
     4741 attccacctt gtataccgcc cgaatgattg gtgcgggtct cgatacgtcc gttgttgttg
     4801 taaaacacgt cattctgttc cgagcctttt tgctttaatc ccttgaaacc gtctccatac
     4861 tcgaatgctt ttgccgcatt gatgctgagc atggctgctc cgagcgctgc atggagcttg
     4921 ccgaataccg gttgtcccag tccgatgggg catcctttaa cgacacaagt caccactcct
     4981 ccgatggtat ctccttctcc ctttatcttg aagatgagtt cttccatttc ttttgccttc
     5041 gccgggtcgg ggcagcggac cggattggtc tctatcaggt cgaggtcgta tgcggtataa
     5101 ttttcttcaa ggcggatagg acctacttgt gaagtgtacg ccgtgatgta tatacccagc
     5161 tgcttcagcg ccaatttggc cagggcgccc gccactacac gcgagattgt ttcacgggct
     5221 gatgaacgtc cgcctccgcg gtggtcgcgg atgccatatt tcactttata agtataatcg
     5281 gcatgtgacg ggcggtagac ttctttcaga ttattgtaat cgtcagaatg ctggttttgg
     5341 ttccatacaa tgaatcctat ggggcagccc gtggattttc cttcgaagat gccggagagg
     5401 aactccactt tatcaccttc tttccgggcg gtagtgatac gtgactgtcc ggggcggcgt
     5461 cggtcgagtt ctgcctggac gaaatccata tcaatgacta ttcctgcagg gaatccgtct
     5521 atcactcctc ctacaccctt accgtgtgat tccccaaaac tggtaaggcg gagaatattt
     5581 ccaaatgagt tgaacatatc aaatgcttta aaggtttata tatgaggctc atgcgccaat
     5641 atctctctta tgaaaatact tttcacttta taaaggtaac aacttttttt gggattcgtt
     5701 tgaatgaaaa gcattttttt gcattaagac tgcatggctt tcatttaagg gagttgaggg
     5761 catatgcgat aaagaagtga aaaccaagct tgcggatagg tgtcccaaag ttggggatat
     5821 gcgttccaag gttgggcatg tctatcccaa ggcttgggat agaacttgcg acatgtcttt
     5881 ggcattttta caacaaatac ttaagaactt tattatatgt atcttgcaac ttttttgcaa
     5941 atgtctattg ggcgggaaac ttatgtcctg tggcaggatt gccgttcttt ggcagagcaa
     6001 caatgaagag ggagcgattc tcgataattt ctctgactct tttgaatgaa cccttcaaat
     6061 gaagagccgt gattaagact gccaccgttg ctgcatttaa atacggagag tattaaaaat
     6121 agaacatcct ttttttagaa aagaccttgt actgtaacct taaaaggtgt tactttgcac
     6181 tcttgatttt aaaataggaa attgatggct tctagggaag ccttttatta actaaacaag
     6241 tattcttaaa agtatgaaaa agaatttatt ttatttgttt gcattgattt gttcaatgag
     6301 tttgtttacg gcttgtagtg atgatgacga tgaagttaag tcacttccgg aagtaaatgc
     6361 ttcttatgta tcgtcggagc tggaacttac ttatggtggt gaagtgcttt tgggaaagaa
     6421 ggtcactttc aatacggcag atgggaaaag tgccgacatt acattagagg gtgctgatat
     6481 tgcgttgact aaagagacta tggcatccgg actggtaaat ccgggcgtga taccgggcga
     6541 acctaaggtt acgttttcag cggctttgca accggcagaa agtggctata cttttgcagg
     6601 tgaacatgtt gccgataatt atagcatgaa atatgaaggt gctgtagaga aaggcaaatt
     6661 gaatctggcc ttggaagtaa agttggccgg tgacaatgcg ttggctggaa acacatggaa
     6721 tcttttctct tatgaccctt atgcggagaa aaatccgttg catgttgttt ggaactcgga
     6781 gaaaccgttc tctgtagttc tggtcccttt tcctggtgct cagcctgttg aacttcaacc
     6841 gggtgcgttt atcactttga tgtctgccat gggtattata ccggtaggag acaaaaagat
     6901 gggagtgaat gagatattgt cttgtttgtt gcagagcgtt actttcaggg aagatggcaa
     6961 tattgtagct tcttattctg atgtggccga tatagtttca ccaaaattcc agaattctcc
     7021 gttgaatatg gtacagtatg cggtgaaaaa tgagaaactg tatttatact tgaatgtgga
     7081 tgccatcata ggtgctgtgc agaaaatgac taccaagggg ctggatatgg aaactgttat
     7141 tccggttgtg ctgcctaaat tgatggaatt gattccgatg ctttccagcg gaattccttt
     7201 gggctattcg gttaatgaag aaggcaatga actggctgtt tatattgaca aagagttggg
     7261 atcgaaactt attgatattc tgttgtcttt attagagaat gaagaaattg tagccgccat
     7321 taaagaagct gctacaagta atccggactt cgctatgttt gcaggtgttg tagaagctat
     7381 attggaacaa gcaccggaag tgtttgccaa aacaaatgag atggaacttg gattgaactt
     7441 tgtgaaatga gataactgtt tcaaataata catccgtgtt tttcttgaag agaccgaact
     7501 ctgttgtaaa ataggagttc ggtctctttt tattttagtt ttttttctac atttgcagta
     7561 tcgataatta aataattaag acggatatga cggagacaga acgacagcaa atcatctcat
     7621 tggtcaagcg tgaagtaatt cctgctattg gttgtacaga acctattgca gtggcgttat
     7681 gtgtggcgaa agctgcggaa gtattgaaca agcgcccgga gaaagtaacg gtgcttttaa
     7741 gtgccaatat cttgaagaat gcgatgggcg taggcattcc gggtacggga atgattggac
     7801 tgcccattgc cgtggcgttg ggcgctttga taggcaagtc cgaatatcag ttggaagtct
     7861 tgaaagacag tacgccggaa gcaatggagg caggaaagcg ttttattgac gaaaagcgta
     7921 ttcatatatc cttaaaaaac gatatagaag agaaactcta tatagaagtg tgttgcgagg
     7981 ccggaggaga taaggcgacc gctattattg ccggtgggca taccaccttt atatatgtgg
     8041 cgcgcaacag cgaagtgttg ttgaataagc aagctgtcgc aagcacggaa gcagagggga
     8101 atactttgga tttgtctctc cgtaaagtct atgacttcgc attgaccgcc ccactggacg
     8161 aaatccgttt tattctcgaa actgcccgtc tgaacaaggc cgccgccgag cgttctttcg
     8221 agggcaatta cgggcatggc ctgggaaaaa tccttcgtgg cacgtacgaa catcgtgtga
     8281 tgggcgacag tgtcttttca catatccttt cttatacttc gggtgcgtgc gacgcccgta
     8341 tggcaggtgc catgattccg gtgatgagta attccggcag cggtaaccaa ggtatatccg
     8401 ctacgttgcc ggtcctgatt tatgccgagg aaaacggaaa atcggaggaa gagattgtcc
     8461 gtgcccttat gttgagccat ttgacagtga tttatatcaa gcagagtttg ggacgtttgt
     8521 ccgccttatg cggttgtgtg gttgctgcta ccggttccag ctgtggcatc acttggctga
     8581 tgggcggtgc atacgagcag gtgtcatacg cagttcagaa tatgattgcc aatcttaccg
     8641 gaatgatttg tgatggtgcc aaacccagtt gtgcattgaa agtcaccacc ggggtttcca
     8701 ccgcagtgct ttcggccatc atggccatgg aaaaccgttg tgtaacttcc gtggaaggta
     8761 ttattgatga ggatgtggat cagagtatcc gtaatctgac aaaaatcggt tctaaaggaa
     8821 tgaatgaaac ggataaattg gtattggaga taatgacaag taaataatat agaatttgaa
     8881 aattaaagaa ttaaaaatta aagaattacc atgcggcatg cttaatactg tgtagtctga
     8941 ttctttaatt tttaattctt taatttttaa ttctttagtg gcagcatccg cctccacatt
     9001 catggtcgcc gcatccgtcg ccacagtcac cacaaccgca gctgccgcaa ccgccaccca
     9061 tcatacgggc aacttcagca agctcttcgt tcgtagccgg acggctttcc accacttctc
     9121 cggtaaagtt caaatcacaa cctgcgagtg gatgattcat gtccattaca actacgtctt
     9181 cctttacttc tactacactt ccattgatgc gttgaccttc agaagtcatc aaggggatga
     9241 cggcgccttc cactacacgg tcgctgtcga attctccttc tatcatgaag atttctttgg
     9301 ggaggtcaat aacatggtcg tcgtcatatt caccataagc ttctgatgcc ggaatggtaa
     9361 agtcgaattt atcgcctatc tgcaagtctt ttatctgggc ttcaaagggt tcgagtgtca
     9421 ttcccagacc tgagataaac tgaaaaggat gctctacggg tgcttcttct tcgaaatctt
     9481 tttctccgtt ttcgattgag tacagcttat atgctacggt gatgtacttg ttttctactg
     9541 tttccattaa ttttctatct ttatttaatt agtaaatact tttttttgag tatttgaaga
     9601 gacaaagata cgaattattt gtttcgggat gtagagagcc tttggtaatt ttcagattat
     9661 taaatggttt caatgattgg caatacattt acattggctg tctgaatggt tctatttaga
     9721 actgttaagt gataaaatag gattttaggg cgacattttc ttacgattat tcatatttat
     9781 cttatttttt tcttcaattt gtttggagat tataaaaaag cccttacctt tgcagcacgt
     9841 ttgaaacaaa aaagaagaat taagttatga atttatatac atctattaac ctggcagtcc
     9901 tgcatattat tcgcgtcgtg gtggtggcat caagagcgtg agaaaggtta tgtatgtatt
     9961 cgtacgttag aagataattt attaagcctt tctcactata gtgggagagg ctttttcatt
    10021 aaaaggagat ttgaaaatga agcatcagtt acgcagctcg ttcagcacac aaggtcgccg
    10081 catggcggga gcccgtgcat tgtggacggc gaatggtatg aagaaggaac agatgggtaa
    10141 gcccattatc gctatagtca attcatttac acaattcgtc cccggacatg tacacctgca
    10201 cgaaataggc cagtttgtaa aggaagagat tgaaaagctg gggtgttttg ctgcggagtt
    10261 caatacgatt gccattgacg acggtatcgc tatgggacac gacggtatgc tttattccct
    10321 gccttcaaga gatatcattg ccgatagtgt ggagtatatg gtaaatgccc ataaggcgga
    10381 tgctatggtt tgcatcagta actgtgacaa gattactccg gggatgttga tggcggctat
    10441 gaggctgaat ataccgactg tgtttgtttc aggcggtccg atggaagccg gggaatggaa
    10501 cggacaacat ttggatttga ttgatgctat gattaaatct gctgatgaaa gtgtgggcga
    10561 taaagaggtg gcacagattg agcaacatgc ctgccccact tgcggatgct gctcaggcat
    10621 gtttaccgct aattccatga attgcttgaa tgaagcgatt ggattggcac tgcccggtaa
    10681 cggcacgatt gtagccactc acgaaaatcg caagaaacta tttgaggatg cagccaggtt
    10741 gattgtagag aatgccttta gatattatga agaaggggat gagagtgtac tcccgcgcag
    10801 tattgctacc cgcgaggcat ttttgaatgc catgacgctg gatattgcga tgggcggttc
    10861 cactaatacg gtacttcatt tgttggctgt ggctcacgaa gccggagcgg attttaagat
    10921 ggacgacatt gacatgctct cccgcaagac cccctgctta tgcaaggtgg ctcccaatac
    10981 ccaaaagtat catgtacaag acgttaaccg tgccggtggc atcattgcca tcatggatga
    11041 gcttgccaag ggcggattgg tcgatacgaa tgtccaccgt gtggatggaa tgacgttggc
    11101 agaggcaatc gaccggtata gtattaccag ctctgatgta tgtaaagagg caatcaagaa
    11161 atactccagt gcggcagccg gaaagttcaa tctggtactc ggctcacaaa atgcgtctta
    11221 taaggaactc gatacggacc gtgcgaccgg ttgtatccgt gatttggaac atgcatacag
    11281 caaggatggt ggtctggcgg ttttgaaggg aaatatagct caggacggtt gcgttgtcaa
    11341 gactgccggt gtagacgaga gtatctggaa atttacgggg ccggcgaaag tcttcgactc
    11401 acaagatgcg gcttgtgacg gtattctggg tggaaaggtg gtcagtggag acgtcgtcgt
    11461 catcacttac gaagggccga aaggtggacc gggtatgcaa gagatgcttt atcctacttc
    11521 ttatatcaaa tcccgccatc tgggtaagga gtgtgcattg attaccgacg ggcgtttcag
    11581 tggtggtact tccggactaa gtatcggaca tgtttctccc gaagcggctg ccggtggtaa
    11641 tatcggcaag attaaggatg gggacattat cgaaattgat ataccgaacc gttctatcaa
    11701 tgtgaagttg acggatgaag agcttgcagc acgccctatg actccggtaa cccgcaaccg
    11761 tgaagtctcc aaagcattga aagcatatgc cagtatggtg agttccgctg acaaaggggc
    11821 tgtgaggctg attgattaaa agcccccctt tccgaaagcg aggggaggag agaatgaaac
    11881 aaatttttca agctactatt gagcttttaa atataatgaa tagataaagt atggctgata
    11941 ataataaaaa gagtaacttt tcctccctct cccaaggaga gggtcggggt gaggctctaa
    12001 taacaggcgc agaagcattg atgcgctctc tggagcatca gggagtaaag actattttcg
    12061 gttatccggg agggagcatc atgccggtat tcgatgcctt atacgaccac cggaaggaat
    12121 tgaaccacat cttggttcgc catgaacaag gagcaaccca tgcggcacaa ggctttgcac
    12181 gtgtatcagg cgaggttggc gtttgtctgg ttaccagtgg accgggtgct accaatacta
    12241 tcacgggcat tgcagatgcc atgattgaca gtacgcctat cgttgtcatt gccggccagg
    12301 tagggacgaa ctttctgggt acggatgcat ttcaggaagt ggacttggta ggcattactc
    12361 agcctatcac gaaatggagt taccagattc gtcgtgcaga agatgtggcc tgggcagtgg
    12421 cacgtgcttt ctatgtggca aagagcggac gtccgggacc ggtcgtgctg gattttgcta
    12481 aaaacgccca agtggagaaa acagaatatg cgcctactaa ggtggactat gtccgtagct
    12541 atcttccagt tcccgaaatg gagccggagg ccatacggca ggctgctgaa ttaataaatg
    12601 gtgcggaacg gcctttggtg ctggtaggac aaggcgtgga gctgggagaa gcccagcaag
    12661 agcttcgtgc tttcattgag aaagccggaa tgcctgccgg atgcacttta ttgggacttt
    12721 ccgcattgcc tacggaccat ccgttgaaca aaggaatgct tggtatgcac ggtaacctgg
    12781 ggcccaatat caataccaat aaatgtgatg tccttatcgc cgtaggcatg cgctttgatg
    12841 accgtgtgac gggcaaattg gaaacatatg ccaagcaggc gaagattatc cactttgata
    12901 ttgaccctgc cgaaatagat aagaatgtaa aaaccgatgt tgctgtcttg ggagattgca
    12961 aagagacact ggctgccgtt acccaattgc tggaacccgc caaccatcag gaatggattg
    13021 acagtttccg acaatacgag gaagtggaag aggaaaaggt aatccgtccg gaattacatc
    13081 cggcaggaaa agcgctaagc atgggtgaag tggtgcgtgc tgtgagtgag tctacccata
    13141 acgaggcgat attggtgact gatgtcggcc agaatcagat gatgtccgcc cgttatttca
    13201 aatacagtaa ggaacgtagc attgttactt ccggtggcct gggtactatg ggcttcggcc
    13261 ttccggcagc tatcggtgcc acttttggac gtccggaccg cacggtatgc gtattcatgg
    13321 gagacggcgg cttgcagatg aacctgcagg aactgggtac catcatggaa caaaaggctc
    13381 cggtgaagat gattctgttg aacaataact tcctgggcaa tgttcgtcaa tggcaggcga
    13441 tgttcttcaa tcgtcgttat tcgtttactc cgatgatgaa tccggattat atgaagattg
    13501 cttcggcata tgatattcct gcacgcaggg taatgacccg cgaggagctg gcaaaagcga
    13561 ttgacgagat gatagcgact gacggaccgt tcctgctcga agcttgtgtg gaggaagaag
    13621 gaaatgtaat gccgatgaca cctccgggcg gttcggtcaa tcagatgttg ttggaatgct
    13681 gaagtcatac gaaattaaag aatttactct atctatggat aaaaaactat atacaatcat
    13741 tgttcattcg gaaaactttg ccggtttgct gaatcaggtg acggctgtgt ttacccgccg
    13801 gcagataaac atcgagagtt tgaatgtatc ggcctcctcc atcaaggggg tacataaata
    13861 taccattacc gcttggacgg ataaggatac cattgaaaag gtgaccaagc agattaccaa
    13921 gaaaatagat gtgctgcaag cccattattt cacggatgat gaaatctatc agcacgagat
    13981 tgccctttat aaaataacga cccctacgct ggaagaaaaa ccggaggtgt ccaaagtaat
    14041 ccgtaagtac aatgcccgta ttgtggaggt gaatgctgta tttgccattg ttgagaagaa
    14101 tggcatgagt gaggaaataa ccaatcttta tgaggagttg cgccagttgg attgcgtact
    14161 tcagttcgtc cgttcgggtc gcgtagccat tacgaccagc tgctttgagc gtgtcaatga
    14221 atatctggcg gaccgtgaag caaaatatcg tcaaagtaaa caccaggaat catgatgagc
    14281 gagaacaata aaataggtac ctacaagttt gttgccgaac cgtttcatgt cgactttacc
    14341 ggacggctga ccatgggagt attgggcaac catttgttga attgtgcggg tttccatgcc
    14401 agcgaccgcg gttttggcat cgcgactcta aacgaggaca attatacttg ggtattgtcc
    14461 cgtctggctg tcgaactgga tgaaatgcct tatcagtacg aagatttctc cattcagact
    14521 tgggtggaga atgtctatcg cctttttaca gaccgtaatt tcgctatcat cgataaagag
    14581 ggcaagaaga ttgggtacgc acgttccgtt tgggcgatga ttagcatgaa tacccgtaag
    14641 ccggcagatt tgctggctct tcatagtggc agcattgtag attatgtttg cgatgaacct
    14701 tgcccgatag aaaaaccttc gcggataaag gtggcctcaa aggaaccggt tgctactttg
    14761 gtagccaaat acagtgatat tgacattaac gggcatgtga acagcatccg ttacatcgag
    14821 catatccttg atttgttccc gatagagatg tataaggaga agcgcatccg tcgttttgag
    14881 atggcatatg tagccgaaag ctattatggg gatgagttga ctttgttcat ggatgatgcc
    14941 ggtgagggcg tttacgatgt ggaggtgaaa aagaatggca gcgaagtggt ctgtcgctct
    15001 aaagtgatgt ttacagagaa ataaataaat ttatcaacgt tggcgtaagc cacaaataaa
    15061 aattaaaaca aaaaatggca caattgaatt ttggcggtgt tattgagaat gtaatgaccc
    15121 gcgaagaatt tcctttggaa aaagcacgtg agatttt
//
