LOCUS       c00134_gnlPro..         9643 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDFOCCGP_134.
ACCESSION   c00134_gnlPro..
VERSION     c00134_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:08:06
            Original ID  :: gnl|Prokka|HDFOCCGP_134
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9643
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9643
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1113:7195]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1114..7195
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..9643
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9643
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(51..623)
                     /locus_tag="ctg134_1"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDVVVMDMNHPLAGCDLNFTGEVVESRPATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             1114..2916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_2"
                     /sec_met_domain="ILVD_EDD (E-value: 4.4e-219, bitscore:
                     717.3, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKRLFEDAAKLIVANAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARPMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             3008..4759
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.8e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             4792..5352
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_4"
                     /sec_met_domain="ALS_ss_C (E-value: 4.8e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQEL"
     CDS             5349..6101
                     /locus_tag="ctg134_5"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVATL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVMFTEK"
     CDS             6152..7195
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg134_6"
                     /sec_met_domain="IlvN (E-value: 3.1e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.8e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(7257..9170)
                     /locus_tag="ctg134_7"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQLLLRMEYEYEKEEFKRQTENMG
                     IARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGASKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NSELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     ISGNRILEEKIDFGIISPYKAQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVIMGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             9285..9641
                     /locus_tag="ctg134_8"
                     /transl_table=11
                     /translation="MVYDLTMLKAFYAAYSEKIERVRNVLQRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDIATATKTNEEVY"
ORIGIN
        1 atactgtgta gtctgattct ttaattttta attctttaat ttttaattct ttagtggcag
       61 catccgcctc cacattcatg gtcgccgcat ccgtcgccac agtcaccaca accgcagcta
      121 ccacaaccgc cacccatcat acgggcaact tcagcaagct cttcgttcgt ggccgggcgg
      181 ctttccacca cttctccggt aaagttcaaa tcacaacctg cgagtggatg attcatgtcc
      241 attacaacta cgtcttcctt tacttctact acacttccat tgatgcgttg accttcagaa
      301 gtcatcaagg ggatgacagc gccttccact acacggtcgc tgtcgaattc tccttctatc
      361 atgaagattt ctttggggag gtcaatgaca tggtcgtcgt catattcacc ataagcttct
      421 gatgccggaa tggtaaagtc gaatttatcg cctatttgca agtcttttat ctgggcttca
      481 aaaggttcga gtgtcattcc cagacctgag ataaactgga aaggatgctc tacgggtgct
      541 tcttcttcga aatctttttc tccgttttcg attgagtaca gcttatatgc tacggtgatg
      601 tacttgtttt ctactgtttc cattaatttt ctatctttat ttaattagta aatactgttt
      661 ttttgagtat ttgaagagac aaagatacga attatttgtt tcgggatgta gagagccttt
      721 ggtaattttc agattattaa atggtttcaa tgattggcaa tacatttaca ttggctgtct
      781 gaatggttct atttagaact gttaagtgat aaaataggat tttagggcga ttttttctta
      841 cgattattca tatttatctt atttttttct tcaatttgtt tggagattat aaaaaagccc
      901 ttacctttgc agcacgtttg aaacaaaaaa gaagaattaa gttatgaatt tacatacatc
      961 tattaacctg gcagtcctgc atattattcg cgtcgtggtg gtggcatcaa gagcgtgaga
     1021 aaggttatgt atgtattcgt acgttagaag ataatttatt aagcctttct cactatagtg
     1081 ggagaggctt tttcattaaa aggagatttg aaaatgaagc atcagttacg cagctcgttc
     1141 agcacacaag gtcgccgcat ggcgggagcc cgtgcattgt ggacggcgaa tggtatgaag
     1201 aaggaacaga tgggtaagcc cattatcgct atagtcaatt catttacaca attcgtcccc
     1261 ggacatgtac acctgcacga aataggccag tttgtaaagg aagagattga aaagctgggg
     1321 tgttttgctg cggagttcaa tacgattgcc attgacgacg gtatcgctat gggacacgac
     1381 ggtatgcttt attccctgcc ttcaagagat atcattgccg atagtgtgga gtatatggta
     1441 aatgcccata aggcggatgc tatggtttgc atcagtaact gtgacaagat tactccgggg
     1501 atgttgatgg cggctatgag gctgaatata ccgactgtgt ttgtttcagg cggtccgatg
     1561 gaagccgggg aatggaacgg acaacatttg gatttgattg atgctatgat taaatctgct
     1621 gatgaaagtg tgggcgataa agaggtggca cagattgagc aacatgcctg ccccacttgc
     1681 ggatgctgct caggcatgtt taccgctaat tccatgaatt gcctgaatga agcgattgga
     1741 ttggcactgc ccggtaacgg cacgattgta gccactcacg aaaatcgcaa gagactgttt
     1801 gaggatgcag ctaagttgat tgtagcgaat gcctttagat attatgaaga aggggatgag
     1861 agtgtactcc cgcgcagtat tgctactcgc gaggcatttt tgaatgccat gacgctggat
     1921 attgcgatgg gcggttccac taatacagta cttcatttgt tggctgtggc tcacgaagcc
     1981 ggagcggatt ttaagatgga cgacattgac atgctctctc gcaagacccc ctgcttatgc
     2041 aaggtagctc ccaataccca aaagtatcat gtacaagacg ttaaccgtgc cggtggcatc
     2101 attgccatca tggatgagct tgccaagggc ggattggtcg atacgaatgt ccgccgtgtg
     2161 gatggaatga cgttggcaga ggcaatcgac cggtatagta ttaccagctc taatgtatgt
     2221 aaagaggcaa tcaagaaata ctccagtgcg gcagccggaa agttcaatct ggtactcggc
     2281 tcacaaaatg cgtcttataa ggaactcgat acggaccgtg cgactggttg tatccgtgat
     2341 ttggaacatg catacagcaa ggatggcggt ctggcggttt tgaagggaaa tatagctcag
     2401 gacggttgcg ttgtcaagac tgccggtgta gacgagagta tctggaaatt tacggggcca
     2461 gcgaaagtct tcgactcaca agatgcggct tgtgacggta ttctgggtgg aaaggtggtc
     2521 agtggagacg tcgtcgtcat cactcacgaa gggccgaaag gtggaccggg tatgcaagag
     2581 atgctttatc ctacttctta tatcaaatcc cgccatctgg gtaaggagtg tgcattgatt
     2641 accgacgggc gttttagtgg cggtacttcc ggactaagta tcggacatgt ttctcccgaa
     2701 gcggctgccg gtggtaatat cggcaagatt aaggatgggg acattatcga aattgatata
     2761 ccgaaccgtt ctatcaatgt gaagttgacg gatgaagagc ttgcagcacg ccctatgact
     2821 ccggtaaccc gcaaccgtga agtctccaaa gcattgaaag catatgccag tatggtgagt
     2881 tccgctgaca aaggggctgt gaggctgatt gattaaaagc ccccctttcc gaaagcgagg
     2941 ggaggagaga atgaaacaaa tttttcaagc tactattgag cttttaaata taatgaatag
     3001 ataaagtatg gctgataata ataaaaagag taacttttcc tccctctccc aaggagaggg
     3061 tcggggtgag gctctaataa caggcgcaga agcattgatg cgctctctgg agcatcaggg
     3121 agtaaagact attttcggtt atccgggagg gagcatcatg ccggtattcg atgccttata
     3181 cgaccatcgg aaggaattga accacatctt ggttcgtcat gaacaaggag caacccatgc
     3241 ggcacaaggc tttgcacgtg tatcaggcga ggttggcgtt tgtctggtta ccagtggacc
     3301 gggtgctacc aatactatca cgggcattgc agatgccatg attgacagta cgcctatcgt
     3361 tgtcattgcc ggccaggtag ggacgaactt cttgggtacg gatgcatttc aggaagtgga
     3421 cttggtaggc attactcagc ctatcacgaa atggagttac cagattcgtc gtgcagaaga
     3481 tgtggcctgg gcagtggcac gtgctttcta tgtggcaaag agcggacgtc cgggaccggt
     3541 cgtgctggat tttgctaaaa acgcccaagt ggagaaaaca gaatatgcgc ctactaaggt
     3601 ggactatgtc cgtagctatc ttcccgttcc cgaaatggag ccggaggcca tacggaaggc
     3661 tgctgaatta ataaatggtg cgaaacggcc tttggtgctg gttggacaag gcgtggagct
     3721 gggagaagcc cagcaagagc ttcgtgcttt cattgagaaa gccggaatgc ctgccggatg
     3781 cactttattg ggactttccg cattacctac gaaccatccg ttgaacaaag gaatgcttgg
     3841 tatgcacggt aacctggggc ccaatatcaa taccaataaa tgtgatgtcc ttatcgccgt
     3901 aggcatgcgc tttgatgacc gtgtgacggg taaattggaa acatatgcca agcaggcgaa
     3961 gattatccac tttgatattg accctgccga aatagataag aatgtaaaga ctgatgttgc
     4021 tgtcctggga gattgcaaag agacactggc tgccgttacc caattgctgg aacccgccaa
     4081 ccatcaggaa tggattgaca gtttccggca atacgaggaa gtggaagagg aaaaggtaat
     4141 ccgtccggaa ttacatccgg caggaaaagc gctaagcatg ggtgaggtgg tgcgtgctgt
     4201 gagtgaggct acccataacg aggcgatatt ggtgactgat gtcggccaga atcagatgat
     4261 gtccgcccgt tatttcaaat acagcaagga acgtagcatt gttacttccg gtggcctggg
     4321 tactatgggc ttcggccttc cggcagctat cggtgccact tttggacgtc cggaccgcac
     4381 ggtatgcgta ttcatgggag acggcggctt gcagatgaac ctgcaggaac tgggtaccat
     4441 catggaacaa aaggctccgg tgaagatgat tctgttgaac aataacttct tgggcaatgt
     4501 tcgtcaatgg caggcgatgt tcttcaatcg tcgttattcg tttactccga tgatgaatcc
     4561 ggattatatg aagattgctt cggcatatga tattcctgca cgcagggtaa tgacccgcga
     4621 ggagctggca aaagcgattg acgagatgat agcgactgac ggaccgttcc tgctcgaagc
     4681 ttgtgtggag gaagaaggaa atgtaatgcc gatgacacct ccgggcggtt cggtcaatca
     4741 gatgttgttg gaatgctgaa gtcatgcgaa attaaagaat ttactctatc tatggataaa
     4801 aaactatata caatcattgt tcattcggaa aactttgccg gtttgctgaa tcaggtgacg
     4861 gctgtgttta cccgccggca gataaacatc gagagtttga atgtatcggc ctcctccatc
     4921 aagggggtac ataaatatac cattaccgct tggacggaca aggataccat tgaaaaggtg
     4981 accaagcaga ttaccaagaa aatagatgtg ctgcaagccc attatttcac ggatgatgaa
     5041 atctatcagc acgagattgc cctttataaa ataacgaccc ctacgctgga agaaaaaccg
     5101 gaggtgtcca aagtaatccg taagtacaat gcccgtattg tggaggtgaa tgctgtattt
     5161 gccattgttg agaagaatgg catgagtgag gaaataacca atctttatga ggagttgcgc
     5221 cagttggatt gcgtacttca gttcgtccgt tcgggtcgcg tagccattac gaccagctgc
     5281 tttgagcgtg tcaatgaata tctggcggac cgtgaagcaa aatatcgtca aagtaaacac
     5341 caggaattat gatgagcgaa aacaataaga taggtaccta caagtttgtt gccgaaccgt
     5401 ttcatgtcga ctttaccgga cggctgacca tgggagtatt gggcaaccat ttgttgaatt
     5461 gtgcgggttt ccatgccagc gaccgcggtt ttggcatcgc gactctaaac gaggacaatt
     5521 atacttgggt attgtcccgt ctggctgtcg aactggatga aatgccttat cagtacgaag
     5581 atttctccat tcagacttgg gtggagaatg tctatcgcct ttttacagac cgtaatttcg
     5641 ctatcatcga taaggagggt aagaagattg ggtatgcacg ttccgtttgg gcgatgatta
     5701 gcatgaatac ccgtaagccg gcagatttgc tggctcttca tagtggcagc attgtagatt
     5761 atgtttgtga tgaaccttgc ccgatagaaa aaccttcgcg gataaaggtg gcctcaaagg
     5821 aaccggttgc tactttggta gccaaataca gtgatattga cattaacggg catgtgaaca
     5881 gcatccgtta catcgagcat atccttgatt tgttcccgat agagatgtat aaggagaagc
     5941 gcatccgtcg ttttgagatg gcatatgtag ccgaaagcta ttatggggat gagttgactt
     6001 tgttcatgga tgatgccggt gagggcgttt acgatgtgga ggtgaaaaag aatggcagcg
     6061 aagtggtctg tcgctctaaa gtgatgttta cagagaaata aataaattta tcaacgttgg
     6121 cgtaagccac aaataaaaat taaaacaaaa aatggcacaa ttgaattttg gcggtgttat
     6181 tgagaatgta atgacccgcg aagaatttcc tttggaaaaa gcacgtgaga ttttgaaaga
     6241 tgaaacaatt gcagtaatcg gttatggcgt acaaggcccg ggccaggctt gcaacttgcg
     6301 tgataacggt ttcaatgtga ttgtaggaca acgtccgggt aagacatacg aaaaggctgt
     6361 ggctgacgga tgggtaccgg gtgagacttt gttcggcatc gaagaggctt gtcagaaagg
     6421 tactatcgtc atgtgtctgt tgtctgacgc agctgtaatg tctgtatggc cgactatcaa
     6481 accttatttg actcccggaa aggctcttta cttctctcat ggttttgcta ttacctggaa
     6541 cgaccgtacc ggcgtggttc ctcctaaaga tattgatgtt attatggttg ctcccaaagg
     6601 ttccggtact tcacttcgta ccatgttcct cgaagggcgt ggcttgaact catcatatgc
     6661 cgtctatcag gatgctacgg gtaaggcttt tgacaagacg attgcactgg gtatcggtat
     6721 tggttcggga tatttgttcg agacaacttt catccgcgaa gccacttccg acttgaccgg
     6781 tgaacgcggt tcattgatgg gtgctatcca gggattgctg ttggctcagt atgaagtatt
     6841 gcgcgaaaac ggccatactc cttctgaagc attcaatgaa acagtggaag agttgactca
     6901 atctttgatg ccattgtttg ccaagaacgg tatggactgg atgtatgcca actgttctac
     6961 tacggcacag cgtggtgcgc tggattggat gaccccgttt catgatgcca tcaagccggt
     7021 tgtacagaaa ttgtatgcaa gtgtgaagtc gggcaacgaa gctcagattt ctatcgacag
     7081 taactccaaa cccgattatc gtgagaagct gaatgcagaa ttgaaagcct tgcgtgaaag
     7141 cgaaatgtgg cagacagctg ttacagttcg taaacttcgt ccggaaaaca attaatcagc
     7201 tttatataaa taggtgaaat accctcttcg gtgttaccgg agggggtatt tctttattat
     7261 tgattcccta tattttgaat aaactccagt agcttccggt aaaaaccgtg atgtttcagc
     7321 gtctctgcct ctcccattat caccagcttc atacgtgccc gggtgatggc tacattcatt
     7381 ctccttaaat cattcaggaa tcctatctgc ccttcttcgt tggcacggac aaggctgatg
     7441 aagataacat cgcgctcttg cccttggaag ccatccaccg tatttacagt gaacaagctg
     7501 cgataaggct tgagtgaagc gtctgccttt atcttgttgc ggagatattg cacttgtgcc
     7561 ttgtaagggg agatgatgcc gaagtctatt ttttcttcca gaatgcggtt gccactgata
     7621 cggttgatgt agattttcag ttctgatagg agcaggtccg cttccgcctt attaatgcgc
     7681 ccgaaagtct ctcccacaaa ttcttctttg aaatccattt cggaggtgtc aatccagtgg
     7741 atgggggtat cccagtccag gatgccccgg taacgcactt cgggagcggc ttccaactcg
     7801 ccattataaa accattggga aggaaatttc atgatttcct cgtgcatgcg gtattgcact
     7861 ttcagcaaag agacaacggc aggtttgttg gacaccactt tctccatcaa tgttcgttcc
     7921 agacctccac gggcggcttc gtagcatttt atggtgggtg gaagttggca gtggtcaccc
     7981 gccaatacca cgcggtctgc ttttcggata gctatccagc aggcagcctc taaggcctgg
     8041 gctgcttcat caatgaaaag ggtgccgaaa cggcgtccgt tcagcagccg gtgattgctg
     8101 cttaccagcg tggaggctat gacatgtgcc ccatcaaaaa gctctgaatt gatttgtatt
     8161 tccaatgcgg tggcgcggtc gcgcaggcgg ctcatacggc tgcgtactcc ttcgcgttcg
     8221 tcatagctgc cacggcgggc acggctgccc agttcacgga gatttttccg gatgctccac
     8281 agttccggat aaagcggatg gttctcgaaa cgacgctcgt aggtaaagga aagcatcttg
     8341 tcgttgacac gggtcggatt gccgatacgc aggacattga cgccacggtc cacaagtttt
     8401 tccgaaatcc agtcgacggc ggtattgctt tgggcacata ccagtacctg cggttcccga
     8461 tgcagggttt cgtagatggc ttccactaag gtggtcgttt ttccggttcc cggaggacca
     8521 tgtacaatgg ccacgtcgcg ggcacacagc actttgttta cagctgtctc ctgcgtggag
     8581 ttcagccagg gaaaccgtac ggggtagagc tctcggaaac cggctttcga ggctcccagc
     8641 aatatgtccc gcaattcggc caggcggttg cctttggagc gtaacgtatc ttccaaggct
     8701 tcgaacatgg tccgatagga tgtttcgtcg aaataaagtt gcacgccgag gttgtccgtt
     8761 tcctgcactt ccataacggc accggctccg ggcattatcg ctaccatccg tgtctcgtcg
     8821 gcatagctta cggtagcggt gaagttcata taggttattt ttccatcggc agactggcgg
     8881 aaaaaacata cgggacggcc gaactcaaaa ttatgttcta tatcggtatt ttctgtgtgt
     8941 gtaatttcta ttactaattg attcagtgaa ttatagtaac ttcgtcccgg agtggcagga
     9001 taccagcaaa gtccccgttt cactttccgg gcaatcccca tgttttcggt ttggcgtttg
     9061 aattcctctt tttcgtattc gtattccatg cgcagcaaaa gttgttgctg ctggaggtga
     9121 ataataggac tatttgaatc ttgttccttc atggttgcaa aggtaatcat tcttcgcttc
     9181 cgacggaaaa aatgctttat tttgttaaac tattcagcct ttttatttgt ttatgatatt
     9241 aatttgtaat ctttacaata atgaaaaact aaaaaatagt ggttatggta tatgatttaa
     9301 cgatgctcaa agcgttttat gccgcttatt cggagaagat agaacgtgta cggaatgtac
     9361 tacagcgtcc gatgacttta gcggagaaaa ttttgtatgc tcatttgtat gatggggata
     9421 aagtgaagaa ctacagacgg ggagaagact atgtgaattt ccgtcccgac cgtgtggcca
     9481 tgcaggatgc aacggcccaa atggccttat tgcaatttat gaatgcaggc cgtgagcagg
     9541 ttgccgtgcc ttccactgtg cactgtgacc atttgattca agcatataaa ggtgcaaaag
     9601 aagatatcgc gactgctacg aagaccaacg aggaggtcta taa
//
