LOCUS       c00035_gnlPro..        24198 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EBJCHCDD_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:53:32
            Original ID  :: gnl|Prokka|EBJCHCDD_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 24198
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24198
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9491:14198]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9492..14198
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24198
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24198
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             38..3982
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MSNLEQTKQSVADVSVTRQQLIDYEKINDIIEDANGYIWFATSGG
                     VFQYNGEIFYQYRSTVDTTSLCNDAALQFYLSKKGQLYVLTEFGTSVYNNDGSFRTVFK
                     EGEYPYSHDIDETGDGRVFLSVADNGTSIYEYTPSTNAHIKRMAGFSMDIDMNNRLWVW
                     HTGEICCYSTTDFSRVKGIPVDGQLYTSCLIPNGLLAYFTSLGVVFVNTSTLDIEKNVS
                     TSRVVTKLQGKRINRAKRYDNTSMILFGDDGKLYWFDVSGMNVIAQNEAGFPFACDVDD
                     ITSVLKDSHGNIWIGTKLNGYKVIYNKEKRFQTNNDVAQYFQGKDITHVARGVQGDYYV
                     IVAHKQLFRVTNGNFTQPIVTDIASGRGGMDQIFVDSKGFVWLITNTSLLKCTPNGNML
                     TLVKEFPHHCYTVGEDAQGNIWFETNQTLCCLFFGEDSPTKVKENVGLVNVIRQVDAQR
                     ILVSAYAGNLYLVNTVNMQIDELTIPRTRNTGLSCTDFIIDKNHNAWGVSHGLGLLHIN
                     LENKQIKTINSDDICPQMNSIVEDNVGNLWIGTLNGLIRFDPEKKHFLAYHSEDGTGND
                     TYAPMSAVAGWSGDVLMGGTKGLTVFNPTEIKPSERSNIHLEYVASNEELYKGGDKNRL
                     KFVGDSITDVYLPYNNNGVYFFYSTLDFGHFNKQKVEFMLDGVDDKWNSIENASYAYYS
                     HIGSGSYLLNLIALNENGDEICRRKVNVHVVPVPWAQPWLVFGFYPLLTIVLFYVVWRI
                     LRCMRANREQIKRVTMQREQEKYASMMNMKYFTNISHEFRTPLTMIYGATRMLRGSESD
                     GETGNLLNIISQNANRMLKLVNQILDFNKMENGILKLKVTEVDAVPVLNNTINRFAVGF
                     KQKQISVQCFTQDSEMLMPLDVDKFDKILTNLVSNALKYSPEESSIKIDMAFVDKTSVE
                     TLFADSSGIDSDSWLKVVVADTGIGIPKDKQKAVFERFYQIEHSTRQSTWGTGIGLFYT
                     QQLVNLHYGFIKCESNTPKGTVFTFVLPQNIELYKDFIDNTNESPMDDIIDDSTPPELA
                     ISETSVTQLTDEEGKPKILVIDDDTHVLNFMKLLLKDYNVECRTNPIITINEIGDIKPD
                     LIISDVLMTDIDGFEVCNRIKSDPTTCHLPVILLTAYSLPEHQLQGVNAGADAYVVKPF
                     SPDYLLALIKNILSNRRKIRQMLTSSTQITTEEKPMLQSQDGEFIEKFYEYMKSHMTEA
                     EIDIDEILDIFSISRSKFYYKVKDLTGLSPNAFFRTYKLNKAAEMIKNSDEKLTYIADI
                     TGFCSQAYFTASFKKQFGCSPSKYREANRI"
     CDS             4474..5169
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="VQESTATESSVRNWAYRRNSHYNDTYVALGGDRLWSDVDYSSFSV
                     TFNYIPQRSEAYGEDLLTDNKSGIVTPYQHWRKLNDKLYVGSVNTYHKHRFGNASVLDF
                     LWQLSLGWNINKVNQTEDNDRELHSYLYDFHNSRVGVSFTPSYQFHRLGFDAKIGLNTY
                     FQSNRVREQKEVSSIFKHREWNGMNTFILMSIVPGVTSRWPLRWEWMPCSGMCRAMMTA
                     TITCGRWQI"
     CDS             5199..5429
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="VLNFSRQSVFPSVVQLNPYNSSSDTLTVSTGNPYLKPYRVSKLRL
                     AYTLTGGGFFVEPSVSFPMILITSSRIGEIS"
     CDS             5426..5530
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MMFGVRYKYQGCSKPKREQKKLQNADKGFRIISE"
     CDS             5819..6001
                     /locus_tag="ctg35_5"
                     /transl_table=11
                     /translation="MIALLFSYFCYRLTDKSAGLPSLTTQQPMNKLVRERVRAICENII
                     SDGEGKYRALTYVYE"
     CDS             complement(6009..7757)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="Alpha-amylase (E-value: 4e-64, bitscore:
                     208.0, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNPELQLMVYGEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYL
                     KLDKDVKPGKFNLTFTEGKKKLVKEYELKARNKKGCEHKGFDASDALYLLMPDRFANGN
                     PDNDQIAGMAEYKIDRKDPNARHGGDLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGS
                     YHGYATTDYYKVDPRFGTNEEYKQLIEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKD
                     WFNNPDHENNFVQTSFKLTPHVDPYTSQYDADQMNDGWFVPSMPDLNQKNPHVYRYLVQ
                     NSFWWIEFANIDGIRMDTYPYADYDAMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQ
                     KDSKLSAPKNSNLKTVMDFSFFDKINTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASV
                     LAFIENHDTDRFLGEGNNLPMLKQASTLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRK
                     DFPGGWTGDATNALTPAGRTKIQNECYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYA
                     YARQYEGKTVFVMLNGTDAETTVPLKFYKEILKDSKQGKDILSGKTIAFGEELKMAPRE
                     SLVIEL"
     CDS             complement(7970..9238)
                     /locus_tag="ctg35_7"
                     /transl_table=11
                     /translation="MANYDYETALILIDQETPTVPLLYQKGKALKGLGNNLEALSVFQE
                     VVAQDSLNPRAYIEAAECCKSLAKYSEALDYYQNALHINPDNKYARIQYISLLMNMKRY
                     RESLKESNLLAERDSSAYVLHLRAESMGQVYDNTEIMHVIDAYLDIQKRYPNDYLSAAK
                     LGNIYVAGHQYEDAISITEKYRSIDSTNVLVNRINAQAYCLNKDYPKAIERYEQLLQEK
                     DSSFQTCFYAGISYYALEDFYPAHDLLERALKDDNTNINVLYYLGRACSKTSWKEDGVT
                     YLETAVSLAMPSDSVMSRLYVGLADCYKMAFQYTDQANTLLTQYEKYDRQKHKLLYDAA
                     FIYYYYLKDVSKAERYLTAYLKTRPKNSKDKVQEVDADGVPIIGEDNRYNAAENWLKDI
                     REKRKKEDFFKGKVDTASVTPIK"
     CDS             complement(9492..10652)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_8"
                     /sec_met_domain="OAD_beta (E-value: 1e-152, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(10654..11088)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_9"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.2e-21, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             complement(11112..12008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_10"
                     /sec_met_domain="OAD_gamma (E-value: 2.1e-17, bitscore:
                     54.4, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQDDYGVHSAWIEI
                     FNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFWADGEPRRGTFHT
                     NFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQWEVKGGSEDKYV
                     TPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISFKIIGKISVNLSK
                     RNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVEDTILTITRVKRSY
                     SPWSSKIYTLRETPHKK"
     CDS             complement(12076..13629)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_11"
                     /sec_met_domain="CT_Btheta (E-value: 2.8e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(13686..14198)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_12"
                     /sec_met_domain="Glyoxalase_4 (E-value: 8.7e-26, bitscore:
                     81.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFFIKEEFSFFVLLYTFIKKDTILTLIYIVMKISHIEHLGIAV
                     KSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEK
                     NNGNGGMHHLAFAVEDGVAGALAEVEEKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLT
                     ELCEKPE"
     CDS             14392..15879
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGAKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVANFNNQAQQLDIAEEADVIAEKRYKTSVETFMIGKISTLDLNDAQNSKDEARQKHI
                     SELYYYWYYFYQLRSLTLWDFERDTELEADFEEVVRG"
     CDS             16023..17384
                     /locus_tag="ctg35_14"
                     /transl_table=11
                     /translation="MILIIDDDSAVRSSLSFMLKRAGYEVKTAPGPREAMDIVRAEAPA
                     LILMDMNFTLSTTGEEGLTLLKQVKVFRPDVPVILMTAWGSIQLAVQGMQAGAFDFITK
                     PWNNAALLQRIETALELTAAPKEVPEEQTTALNRSHIIGKSKGLMEVLNTVARIARTNA
                     SVLITGESGTGKELIAEAIHINSQRVKQPFVKVNLGGISQSLFESEMFGHKKGAFTDAS
                     ADRIGRFEMANKGTIFLDEIGDLDPSCQVKLLRVLQDQTFEVLGDSRPRKVDVRVVSAT
                     NADLRKMVSERTFREDLFYRINLITVKLPSLRERREDIPLLARHFADRQAEVNGLPRTD
                     FSADALNFLSRLPYPGNIRELKNLVERTILVSGKPVLDATDFDAQYLRHDEPAKAAEGT
                     SFAGMTLDEIERQTILQALEQHKGNLSQVAVSLGISRAALYRRLEKYNIQVPCA"
     CDS             17375..18688
                     /locus_tag="ctg35_15"
                     /transl_table=11
                     /translation="VRIKFFFFILVLFLLGLGGMLVYLLSGKPSLYLYVLEGLIGFILI
                     YLIVFYNKIVKPMNTIGSGMELLREQDFSSRLSRVGQYEADRIVNIFNRMMEQLKNERL
                     RMREQNHFLDLLIQASPMGVIILTMDDEVSQLNPMAVKMLGVRMEEAMTKRLDQMDSPL
                     AAELSSIPKDETAVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTEEVMRAEKRAYEK
                     VIRMIAHEVNNTTAGITSTLDTVEQALSTEDDMEDICDVMRVCTERCFSMSRFITRFAD
                     VVKIPEPTLAPVQLNELVSMCKRFMEGMCNDRNIELRLECDPEVGMVRMDASLFEQVLV
                     NIIKNAAESIEGDAGENGQQGEIIVRTTAPASVEVVDNGPGISKETEAKLFSPFFSTKP
                     NGQGIGLVFIREVLSRHGCTFSLRTYSDGLTRFRILFN"
     CDS             complement(18715..20334)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_16"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-22, bitscore:
                     71.0, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.00043, bitscore:
                     10.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTKLLEKKMESISPFELKNRLIDMADESLKKTARTMLNAGRGNP
                     NWIATAPREAFFLLGSFGLEECRRIMDLPEGIAGIPEKKGIASHFEAFLKKNNNAPGAK
                     LLEQTYNYLLMQHAADPDSLVHEWAESIVGDQYPVPDRILHFTEILVQDYLSQEMCDNR
                     PPRGAYDLFATEGGTAAMCYIFDSLQENFLLNKGDGIVLMVPAFTPYIEIPQLSRYQFR
                     VTKIHANRMNNEGMHLWQYSDEDIDRLKSPKIKALFVTNPSNPPSYTLSPDTMARIVSI
                     VRNDNPNLMIITDDVYGTFSPHFRSFMAEIPYNTLCVYSFSKYFGATGWRNAVIALHEF
                     NLFDKLIAKLPKEKREILHRRYSTLTLEPEKLKFIDRMVADSRQVALNHTAGLSLPQQM
                     QMGLFAAFALLDKENKYKQKMQEIIRRRLHALWENTGFTLTEDPLRVGYYTEIDMLVWA
                     KKFYGDDFVEYLKRTYSPLNVVFRLAKETSLVLLNGGGFDGPEWSVRASLANLDEKDYA
                     TIGQGIKRILDEYAKEFFKSRN"
     CDS             complement(20371..20532)
                     /locus_tag="ctg35_17"
                     /transl_table=11
                     /translation="MQATIYPFTNSYSSDSCRTMIQQLSDEKETYIGRLISSKERNSPP
                     HEQRLFTE"
     CDS             complement(20589..22283)
                     /locus_tag="ctg35_18"
                     /transl_table=11
                     /translation="MEWIFNQLRERPELAIFLTIFLGFWLGKLRIGKFTLGTVTSVLLV
                     GVLVGQLNIAVPGPIKSVFFLLFLFAVGYKVGPQFFRGLKKDGLPQVGFAVLMCVSVLL
                     VTWLLALMMGYNAGEAAGLLAGSQTISAVIGVAEDTMANMGLDEAQRQSYVNIIPVSYA
                     VTYIFGTAGSAWVLSSIGPKMLGGLEKVKAACKELEAKMGSSLADEPGFMPAARPVTFR
                     AYRVENEWFKNGKRVIDLEVYFRQHDKRLFVERLRKSGVVVEVSMNIQIEPGDEVVLSG
                     RREYIIGEESWIGPEVQDAQLLDFPAEKLPVTITRKTVAGKTVAVIRREKFMHGVSIRS
                     IKRAGISIPVLAQTVVDAGDVIEVVGTRQEVEAAAKRLGYIDRPTNQTDMIFVGLGILV
                     GGLFGALSVHIGGIPISLSTSGGALIAGLFFGWLRSKHPTFGRIPEPSQWVLNNVGLNM
                     FIAVVGISAGPSFVQGFHDVGISLFLVGAAATTLPLIIGLLLARYVFKFHPALALGVCA
                     GARTTTAALGAVQDAVESETPALGYTVTYAVGNTLLIIWGVVIVLLI"
ORIGIN
        1 ggagccgtaa ggtgaaatac cgctctgttc gcattggatg tctaacctcg aacaaacaaa
       61 acagtctgtt gctgacgtat ctgttacacg tcagcaactc atagattatg aaaagataaa
      121 tgatattata gaagatgcaa acggatatat atggtttgct acatctggtg gagtatttca
      181 atataatggg gaaattttct atcaatatcg ctccactgtt gacactacaa gcctttgtaa
      241 cgatgctgcc ttgcagttct atctttcaaa gaaagggcaa ctttatgttc ttaccgagtt
      301 tggcacatcc gtgtataaca atgacgggag ttttcgcaca gtctttaaag agggtgaata
      361 tccatactca cacgatattg atgagacggg tgatggacgt gtgttcctca gcgtggctga
      421 caatggtaca tctatctatg aatatactcc atcaacaaat gctcatataa agcgtatggc
      481 tggcttctcg atggatattg acatgaacaa tcgattatgg gtgtggcaca caggcgagat
      541 ttgctgttac tcaacaacag atttcagcag agttaagggc attcctgtcg atggacagct
      601 atatacatcg tgtttgattc ccaatggtct tctggcttac tttacatcac taggcgtcgt
      661 ttttgtaaat acatcaaccc tcgacatcga aaaaaatgtt tctacatcaa gagtagtgac
      721 gaaactgcag ggaaagcgta taaatagggc gaaaagatat gataatacat ctatgatttt
      781 gtttggtgat gacggaaaac tctactggtt cgacgtatct ggtatgaatg ttattgctca
      841 aaacgaagcg ggttttccat tcgcctgcga tgtcgacgat attacaagcg tactgaaaga
      901 ctcgcatggc aatatctgga ttggtacaaa acttaatggc tacaaggtta tatataataa
      961 ggagaaacga tttcaaacta ataatgatgt agcacagtac tttcaaggga aagacatcac
     1021 acacgttgcg aggggtgtgc aaggtgacta ctatgttata gttgcacaca aacagttatt
     1081 ccgagtaact aatggtaatt ttacccagcc aatagttaca gatatagcat cgggcagagg
     1141 tggtatggat cagatttttg tagatagcaa aggctttgtg tggctcatca ccaacacctc
     1201 gctattgaag tgtaccccca atggtaatat gctaacgtta gtaaaagagt ttccgcatca
     1261 ttgctacact gtgggcgaag atgcccaggg aaacatctgg tttgaaacaa accagacact
     1321 ttgttgcttg ttctttggcg aggatagtcc aacaaaggta aaagaaaacg tgggcttggt
     1381 gaatgttatt cggcaggtag atgctcaacg cattcttgtc agtgcgtatg ccggtaacct
     1441 atatctcgtg aatactgtaa acatgcagat tgatgaactg acaattcccc gcacgcgcaa
     1501 caccggccta tcgtgcacag acttcattat agacaaaaat cacaatgctt ggggggtatc
     1561 acatggactc ggactacttc atataaatct tgaaaataag caaatcaaga ccattaacag
     1621 cgatgatata tgtccacaaa tgaatagcat tgtagaagac aatgttggta atctttggat
     1681 tggaactttg aatggattga ttcgttttga tccagaaaaa aaacatttct tggcttacca
     1741 ttctgaagat ggtacgggaa atgataccta tgctccaatg agtgcggttg cagggtggag
     1801 tggcgatgtg ttgatgggag gtaccaaggg acttaccgtg ttcaatccta ccgaaataaa
     1861 gccaagtgaa aggagtaata tacatctgga atatgtagca tcaaacgagg aactatataa
     1921 aggtggcgat aaaaacagac tgaagtttgt tggcgacagt attacagacg tgtatctgcc
     1981 ctacaacaat aatggggtgt atttctttta ttctactttg gactttggtc actttaacaa
     2041 gcagaaggtt gaattcatgc tcgatggcgt tgacgacaaa tggaactcca ttgaaaatgc
     2101 atcctatgct tattattcgc acattggttc ggggagttat ctacttaact tgattgctct
     2161 aaacgagaac ggtgatgaga tttgtcgccg taaagtaaat gtacacgttg ttcctgtgcc
     2221 atgggcgcag ccttggttgg tatttggctt ttatccatta cttactattg tcttattcta
     2281 tgtggtatgg cgaatattaa ggtgcatgag agcaaacagg gagcagataa aacgtgtcac
     2341 catgcaacgt gagcaggaga agtatgcgtc tatgatgaat atgaagtatt tcaccaacat
     2401 ctcacatgag ttcagaacac ctctcacaat gatttatggt gcaacaagaa tgctacgagg
     2461 aagcgaaagt gatggagaga caggcaatct gctaaatatt atcagtcaga atgcaaaccg
     2521 aatgcttaag ttggtaaacc aaattctgga ctttaataaa atggaaaatg gcatacttaa
     2581 actaaaagtg accgaggttg atgctgtgcc tgtacttaac aatactatta accgttttgc
     2641 tgtgggcttt aagcagaaac aaatttctgt acaatgcttc actcaggatt cagaaatgct
     2701 gatgccatta gatgtggata agttcgacaa aatccttacc aatcttgtgt ctaatgcatt
     2761 aaaatattcg cccgaagaaa gctctataaa gattgacatg gcctttgtcg acaaaacctc
     2821 tgttgaaact ttgtttgcag attcatcagg tatcgactcc gacagttggc tgaaggtagt
     2881 ggtggccgat acgggcattg gcattccaaa agataagcag aaagcagtgt ttgaacgatt
     2941 ctatcagata gaacactcta cacgccagag cacatggggt acgggtatag gactgttcta
     3001 tacgcagcaa cttgtgaatc tgcactatgg atttataaaa tgtgaaagca atactccaaa
     3061 aggaacagta tttacttttg tgttgccaca gaacattgaa ctttataaag actttatcga
     3121 caatactaac gaaagtccaa tggacgatat tattgacgat agtacccctc ccgagctggc
     3181 aatttctgaa acttcagtta cacagctaac agatgaagaa ggaaagccaa agatactggt
     3241 aatagacgac gatactcacg tgctgaattt catgaagctg ttgttgaaag attacaacgt
     3301 ggaatgtcga accaatccca taataaccat taatgagatt ggcgatataa aacccgattt
     3361 aattatcagc gatgttctta tgaccgacat cgatggcttt gaggtgtgca atcgcataaa
     3421 gtcagacccc acaacatgtc atctacctgt gattctgtta acggcataca gtcttcctga
     3481 acatcagctt caaggagtta atgctggtgc tgacgcctat gtagtaaagc ctttcagccc
     3541 cgactatctt ctggcgctaa taaaaaacat cttaagtaat cgccggaaga tccgccagat
     3601 gctcacttcg tcaacccaga taacaaccga agagaagcct atgctacagt cgcaggatgg
     3661 cgagttcata gaaaaattct atgaatacat gaagtcacac atgactgaag ccgagataga
     3721 catcgacgag attttggata ttttctccat tagccgctct aagttctact ataaggttaa
     3781 ggacctgact gggttgagtc caaacgcgtt cttccgtacc tataaattaa ataaagcagc
     3841 agaaatgata aagaacagtg acgagaaact cacatatatc gcggatatta caggtttctg
     3901 cagccaggca tatttcactg cttcgtttaa aaaacaattt ggttgctcgc caagtaaata
     3961 tcgtgaggcc aacaggattt aataacttta aagtaaagat gggcaacagc agcttatctt
     4021 tactttttgt catacaagat tatgaggaca atacattgca ccatcttaca gagataatag
     4081 attctattaa agatattttt aggaatagaa taacaattca ttttaaacgt gtttggcaga
     4141 caattgagca ttgttcttct aataatgaag aactgaaaac agtttttagg actttcatta
     4201 aagaaggctt taatagtctg tcagcccgga ggacatatta tcggtggatg tgacacaaac
     4261 ggcctctgca gaattcatgc gggagggata taccagcgta gtgaacatca agatcaagaa
     4321 aatagaccgg aaatatactg cctttaacgg cggaatcaat tctcattctg tccggcgctt
     4381 tggaattgcc gatgcttcat atgaaacagg aacagcaaat attctctgta cccgacagct
     4441 caaagttttg ccttcctcaa taataagtcg aaggtgcagg aatccactgc cactgaaagc
     4501 tctgtacgca attgggctta tcgccgcaat tcccattata acgatactta tgttgctttg
     4561 ggaggcgacc gcctctggag tgatgtcgat tattcttcgt tcagcgttac cttcaattat
     4621 attccccagc ggagtgaggc ctatggagaa gacttgctga cagacaataa atccggcata
     4681 gtgactccct accaacattg gcgcaaattg aacgataaat tgtatgtggg ttccgtgaat
     4741 acctaccata agcaccgttt cggcaatgcc tctgtcctcg atttcttatg gcagctcagc
     4801 ctggggtgga acataaataa agtgaatcag acggaagata atgaccggga acttcattct
     4861 tatctttatg attttcacaa tagcagggtg ggtgtttcct ttactccatc ctatcagttc
     4921 cacaggttgg ggtttgatgc caagataggt ttgaatactt atttccagtc caaccgggtc
     4981 agggaacaga aggaagtttc ttccatcttc aaacaccggg aatggaatgg gatgaatacc
     5041 tttatcttga tgtcaatcgt gcctggggtg acttctcgct ggccgcttcg ttgggaatgg
     5101 atgccgtgtt caggaatgtg tcgggctatg atgaccgcta ctataacctg cggccggtgg
     5161 caaatttgaa ctatcgtttc aatacccacc attcattggt gctcaacttt agcaggcagt
     5221 ctgtttttcc cagtgtggtg cagctcaatc cctataacag ttcatctgac acattaacag
     5281 tctctaccgg gaatccttat ctgaagcctt atcgtgtcag taagcttcgt ttggcctaca
     5341 cccttacggg aggtggtttc tttgtggagc cgtccgtaag ttttccaatg attttgataa
     5401 caagttcacg aataggggaa atatcatgat gtttggagta cgctataagt atcaaggttg
     5461 tagcaaacct aagcgtgagc aaaagaaact acagaatgca gacaagggat tcaggataat
     5521 ttcggagtaa gtagtctgaa ttatttgttc atccaactta ttacaaatgt tgcacgcagt
     5581 tttaccctca tactctcatg agttgctgta tcccgttatt caccgggtgt gcagctatta
     5641 gagcaaccat gagggaagca tgagagtaag acgttactct catggtataa agcgatttgt
     5701 ctgatagcgg ctcacgttag tgaacaaagc cattcactga ggtgagcaaa gcaaatcacg
     5761 atagtgaaca tttatgttca ctatcgtgat gctaaggcag acaccatact tccaaaggat
     5821 gattgcctta ttgttttctt atttttgcta taggctgaca gataaaagtg caggtttgcc
     5881 ctcacttacc actcaacagc cgatgaacaa gctggtacgg gaaagagtga gggcaatatg
     5941 cgaaaatatt atttctgatg gggaagggaa gtatcgagcc ttaacttatg tatatgaata
     6001 atggctgatt atagttctat cactaacgat tctctgggag ccatctttag ctcttcaccg
     6061 aaagcaatgg tctttccgct aagaatgtct tttccctgct tgctgtcttt caagatttcc
     6121 ttgtagaatt tcaatggaac agtggtctct gcatctgtac cattcagcat cacgaatacg
     6181 gtttttcctt cgtattggcg tgcataggca taaacaccat tctgtaccat gaactgcacc
     6241 atgctgcctt tggcaatcac atcgtttcct ttgcgccagt ttaggatggt cttgtagaag
     6301 tcgtagcact cgttctgtat tttggtacgt ccggctgggg tcagtgcgtt tgttgcgtca
     6361 ccggtccatc cgccggggaa gtccttgcgg acatagccgt cgctcttgct cttcacgcca
     6421 ttcatcatga cttccgttcc gtagtagagt tgcggaatgc ggcgggtggt aagcagcagg
     6481 gtagaggctt gcttcagcat cggaaggttg ttgccttcgc ccaggaagcg gtcggtgtcg
     6541 tggttttcga tgaatgccag tacggaagcg gggttggggt agaggaagtc gtatacgaag
     6601 ttattgtata tgcggtccag tcccttgaac caagtttcgg tctgttcatt cttggcggtg
     6661 tttatcttgt cgaagaagct gaagtccata acggtcttga ggttactgtt cttgggggct
     6721 gatagcttgg aatccttctg ccaccaggcg gtgtaggcgg gttcggtaac ccaggtctcg
     6781 cccacggtgt tgtagttggg atattcttcg ttgagctctt tcatccagtt gctcatggca
     6841 tcatagtcgg catacgggta agtgtccatg cggatgccgt cgatgttggc gaattcaatc
     6901 caccagaaac tgttctgtac caggtagcgg taaacgtgag gattcttctg gttgaggtcg
     6961 ggcatggaag gtacaaacca gccgtcgttc atctggtcgg catcgtactg ggaagtataa
     7021 gggtctacgt gcggggtcag tttgaaggag gtctgcacga agttgttttc gtggtcgggg
     7081 ttgttgaacc agtctttgga gggcatgtcc ttaatccata catgctctac gccgcagtgg
     7141 ttgaaaatca tgtccattac gattttgatg ccgcgtgcat gggctttttc aatcagttgc
     7201 ttgtattctt cgttggtacc gaagcgcggg tctaccttgt agtagtctgt ggtggcatag
     7261 ccgtgatagg aaccgccggt catgttgttt tccagtaccg gagtaaacca gagggctgtg
     7321 acgccgaggt cggagaagta gtccaggtgt tgttcgatgc cggcaaggtc accgccgtgg
     7381 cgtgcattgg ggtctttgcg gtctatcttg tactcggcca tgcccgcaat ctggtcattg
     7441 tccgggttgc cattggcaaa gcggtcgggc atcagcaggt acagtgcgtc ggaggcgtcg
     7501 aaacctttat gttcgcaacc tttcttgttg cgtgccttca gttcatattc ctttacgagt
     7561 ttcttttttc cttcagtgaa ggtgaggttg aatttgccgg gttttacatc cttgtccagt
     7621 ttcagataga ccaggaggta gttgttgctt tccagcttga cggtgctgct caatgagacg
     7681 ccgggataat tgacggatac tgccgcgttg ccgatgcctt cgccatagac catcagctgg
     7741 agttccgggt tctgcatgcc ggtgtaccaa aacggagggt cgattttgtt cacattcata
     7801 gctgcatacg tactgaggga gagtaagagt gttcccaaga ttaagaatac ttttttcatg
     7861 atagtaactt tacggttaat ttttgcgcta atttaaaaca aataacggag aaagttaatc
     7921 tttctccgtt actgtacctt attatattat gcaaacgttt tcattggggc tatttgatgg
     7981 gggttacgct ggcggtatcg acctttccct tgaagaagtc ctctttcttg cgcttttctc
     8041 tgatgtcctt cagccagttt tcggcggcat tgtatcggtt gtcttctccg atgatgggaa
     8101 ctccgtccgc atctacttcc tgcactttgt ccttgctgtt tttcggacgg gttttcaggt
     8161 atgccgtcag atatctctct gctttggaca catctttcag atagtaataa tagataaagg
     8221 ctgcgtcgta gagcagtttg tgtttctgcc ggtcgtattt ttcgtattgc gtcagaaggg
     8281 tattcgcctg gtcggtgtat tgaaatgcca tcttgtagca gtccgcaagc cccacatata
     8341 ggcgggacat gacactgtcg ctgggcatgg cgaggcttac ggcagtttcc agataagtca
     8401 ctccatcctc tttccatgat gtcttggagc aggcgcgtcc cagataatag agaacgttga
     8461 tgttggtatt gtcatcttta agagcccttt ccagcaggtc gtgtgctggg tagaagtctt
     8521 cgagggcata atagctgatt ccggcgtaga agcaggtttg gaaagaactg tctttttcct
     8581 gtaacagttg ttcatatctt tctattgctt tggggtaatc tttgttcagg caataggctt
     8641 gggcattgat gcggttcaca aggacgttgg tggagtctat ggaacggtat ttctccgtta
     8701 tgcttatggc gtcttcatac tggtggcctg ctacatagat gttgccgagt ttggcagcag
     8761 acaggtaatc attgggatat cttttctgta tgtccaggta ggcatctatc acatgcatga
     8821 tttctgtgtt gtcatagact tgccccatac tttcggctct aaggtgtagt acataggcgg
     8881 aactgtccct ttctgccagc aggttgcttt cctttagaga ctcacggtat ctcttcatgt
     8941 tcatcagcag actgatatac tggatgcgtg cgtatttatt gtccggattt atgtggagcg
     9001 cattctggta gtaatccagc gcctcactat atttggcgag tgatttgcag cattcggcag
     9061 cttcaatgta tgctcgggga ttgagagaat cctgagctac gacttcctga aatacgctca
     9121 gagcttcaag gttattgccc agccctttca gcgctttccc tttttggtag agtaggggga
     9181 cggtcggggt ttcttgatcg attagtatca aggctgtttc ataatcgtag ttggccatcg
     9241 cctcttgaat gggatttgtg gtctgtgccg ccagaagcga acagcatgca ctgaaacata
     9301 aggagataaa aagctttcgc atacagtata tcatttatat gaggttaaac tgactgcaag
     9361 ttactaaaaa gaatatattt acgaaataat cgtaatctgt tttagataga ttaacgaaaa
     9421 agcccctcca aaaatgaagg ggctctaaaa tagttcggaa ttcaagccgg ataacggaat
     9481 gaataaatgt attacattaa gaatcccagc aggatacctg ctgctacagc ggaaccgatt
     9541 acaccggcaa cgttcgggcc catggcatgc atcagcagat agttggtagg atcgtattcc
     9601 agacctacta cttgggagat acgtgcagag tcgggtacgg cagatacacc ggcattaccg
     9661 atcaacggat taatcttgtt gcctttcttc aggaagaggt tgaaaatctt cacgaagatg
     9721 acaccggatg ctgtggcaat gacaaatgat aaggcgccca gaccgaatat cttgattgaa
     9781 tcaagggtta agaactcgga tgcttgcgta gaagcaccta ctgtcaaacc aagcagaata
     9841 gtaatggtat caatcagcgg accactggct gtgtttgcca gacgacgtgt aactccactt
     9901 tctttcagta aattaccgaa gaacagcata cccagcaaag gcagaccgga tggtacaagg
     9961 aatgtggtta gtaacaaacc gataatcggg aacattactt tttccgtatg tgaaaccaca
    10021 cggggaggtt tcatacggat aagacgttca tttttactgg tcagccaacg cataataggc
    10081 ggctgtatca ccggtactaa tgccatatat gaataggctg ataccgcaat ggcacccatt
    10141 aagttaggag ccagtttgga agagaggaag atggcagtcg gaccatcggc accaccaatg
    10201 ataccgattg caccagcctg catcgggtca aatcctatgg caagggcaat catataagca
    10261 ccgaatatac cgaattgggc tgctgcacca accaacatta atttggggtt cgatatcaaa
    10321 gcagagaaat ccgtcatggc accgataccc aggaatatga gtggcgggta ccaaccggag
    10381 gttactccct ggtacagaat attaagtacg gaaccttctt catagatacc gactttcaat
    10441 ccggcttcca tattgaaagg tatattacca atcagcatac cgaaaccgat aggaattaat
    10501 agcatcggct caaattcctt ggctacagcc aagtatatga aaaacaaacc taccagaagc
    10561 attaccacat gtcctaccgt tgcattggca aaacctgtat aagtccagaa gtcggcaagg
    10621 ttgtttccta aaaatgtgat aaattctccc atattattca ataattacga ggtcagtacc
    10681 ttcgagaaca gagtcccctt tgtttacatt gatggctgta atcttaccgt ctttatcagc
    10741 attgatattg ttttccatct tcatggcttc caaaatgatg ataacttgtc ccttctttac
    10801 tgtatcgccg acatttactt tgatatcgag gattacaccg ggaagcggag attttacacc
    10861 tgacttgccg gtagaagcag cggccggttt tactaccgga gtagcaggag cagcaggagc
    10921 ggatgtggct gccggacgtg ctaccggttt aacgactacc ttcggtgctt tttccatttc
    10981 aactttgtag ggagtaccgt tcacttctac atgagcgatg ttgtcttcaa tatctccaat
    11041 ggcaacttta tatacgttac cgttaatttt atatttatat tctttcatcg ttttatttta
    11101 ttatgggtga cttacttttt gtgaggagtc tcacgcaacg tataaatctt tgaactccac
    11161 ggtgagtaac tgcgttttac acgggtaatg gtaagtatcg tgtcttccac atcgtgtaca
    11221 tcgctttgga attcgtgcat ggccattgaa atggcagcaa aaacttctcc cggagcctgc
    11281 cccagttgtt tctcttttgc ttcttgttta tcagtaatac ctttagcttt catggcattg
    11341 cgtttgctga ggttaactga tattttacct ataatcttga aggagatgta gagtaatatc
    11401 agcccgcaga atacaacgct catggcagaa atagccatac cgatacctac gctgtcatgc
    11461 tcttcgaatt tttccatttt ggcattgctg tcgatagtct tgttgttggt actcggagtg
    11521 acatatttat cttcgcttcc accctttact tcccattggt cggctgcatc actgacacgg
    11581 gcataggatt ggttggcttt taaagtaccg gcaggcacta tgacttgatc aagcaatttc
    11641 ttgccggaat catacaaccc aatccagttg gcatttgtgg catccagttt gaagttcgta
    11701 tgaaatgtac cgcgtcttgg ttctccatca gcccagaaaa gtgcatgctg acgtggtttt
    11761 atgagtgtca gaacgtcacc tttgggaatg aaataactgg cagtatcacc cggctggctg
    11821 ctgaatttca gatagcaacc tgcaaggtcg gcgctgccgt atgatctgtt gaatatttca
    11881 atccatgcgc tgtgcacacc gtagtcatcc tgatagttgc tttcgttgtt gaccagcact
    11941 tcattcagca gcagtttgtt gttcgatttc tgttctttgc aagaagagca aaagcctaac
    12001 accagcatca atgaaaggaa tattccgatt tttgttttat tcataatcgt tcttgtttta
    12061 gtgtgaaaag cttgattaca agggaatatt accatgcttc ttagccgggt tagtcaattt
    12121 cttggtttgc aactgttgca gggcacgaat gatgcggaaa cgtgtgttac gcggttcgat
    12181 aacatcatca atgtagccat atttagctgc attataagga ttggcaaaca acttggtgta
    12241 ttcagcctct ttttcagcca ggaattgagc cggattttcc tgctctttgg cttcgcgggc
    12301 atataatact tctacggcac ctgcaccacc cattacagcg atttcagcag taggccaagc
    12361 ataattcatg tcgccacgca gctgcttaca gctcatcacg atgtgcgaac caccgtagga
    12421 tttacgcagt gtgatggtaa ccttgggtac agtagcttca ccgtatgcat acagcagttt
    12481 ggcaccgtgc aggatgacgc cgttgtactc ctggccggtt cccggaagga atcccggtac
    12541 gtctaccaat gatacgatag gaatattgaa ggcgtcgcag aaacggacga agcgtgcgcc
    12601 cttgcgggat gcgttgctgt cgagcacacc tgccagatac ttcggctggt tggcaacgat
    12661 acctacggac tgtccgttga aacgtgcgaa accgataatg atattctttg aataatcttt
    12721 ttggatttcg aggaactcac cattatctat gatagcgcca attacctcgt acatatcgta
    12781 cggtttgttc gggttatcag gaatgatgtc gttcagggaa tcttccagac ggtcgatagg
    12841 gtctgtgcag tctacataag gagcttcttc cagattgttc tgtggaatgt agctcaacag
    12901 tttgcggata agagccaagc cttcttcttc agtctgtgca gtgaaatgag taacacctga
    12961 tttggtggag tgaacgctcg cgccacccag gttttcctgg cttacgtctt ctccggttac
    13021 agtctttact accttcggac cggtaaggaa catgtaggat gtaccttcca tcatcagcgt
    13081 aaagtcagtc aatgcaggag agtaaacggc accaccggca caaggaccga aaataccgga
    13141 aatctgcggg atgacaccgg aagcaaggat gttacgttgg aagatttcag cgtagccagc
    13201 caaggcattg ataccttcct gaatacgtgc accgcccgag tcgttgatac cgatacacgg
    13261 agcacccatt ttcatggctt ggtccataat cttacagatt ttcagagaca tggtttcgga
    13321 cagtgaaccg gcagaaactg tgaagtcctg tgcgaagata taaaccagac ggccttcgat
    13381 tgtaccgcaa ccggttacta caccgtcacc ggggtagtgt ttcttttcca tgccgaagtt
    13441 ggtgcatcta tgttctacga acatgtccat ttcttcgaaa ctgccttcgt cgagaagcat
    13501 ggctatgcgc tcgcgagctg tatatttacc cttctcgtgt tgctttgcaa tcgctttttc
    13561 accaccaccg agacgtgctg cagcgcggcg gtctataagc tctttaatct tttcaagttg
    13621 attactcatg aatttatatt ctttaatgtt tatacaattt atggttggac gatttatggt
    13681 cgtgcttatt ccggtttttc gcaaagttca gtcagaacgc cgagggttga cttcggatgc
    13741 aggaatgcaa tgttcagacc ttctgcacct ttgcggggag ctttgtctat aaggcggata
    13801 cctttttctt cgacttcggc aagcgcaccg gccactccgt cttcaacggc gaatgcgaga
    13861 tgatgcatgc caccgttacc gttgttcttt tcgatgaact tggcaattgt gctttcggga
    13921 gaagtaggtt ccaacaattc gatctttaca tcgcccactt tcaggaaagc ggttctaact
    13981 ttctgatctt ccacggtttc gatgttgtag catttcaaac ctaaaacgtt ttcgtagtac
    14041 ggaagggctt cttcaatgct cttaacggca atgcccagat gctcaatgtg tgaaatcttc
    14101 ataactatat aaattaatgt tagtattgta tcctttttaa taaaggtata aagcagcaca
    14161 aagaaagaga attcttcctt aataaagaaa tttttcatca attaattcat ggataattga
    14221 actttagaag gattttttca gactttagat agagaccggt tgttttcctg atatcgtccg
    14281 ctaacggaca tccccactgt ccgaaaatga acacttaccc ctctatgaaa tcttcccggc
    14341 cacttggcac actctttgct tttctgtttg cgacaatttt aaagattgaa catgaaaaag
    14401 aatattttac ttgcagtttg ttttttgatg ccgttggcaa ccatggcgca gaatgatact
    14461 ttgggacatg aacgcaatat tacgctgtcg gaggccattg tactggcccg tacgcagtct
    14521 gtggatgctg ctgtggcatt gaatgaattg aaaaccgcgt attgggaata ccgtacattc
    14581 cgtgcggact tgttgccgga agtgaatttc accggtacac tacccaacta taacaagtcc
    14641 tacagtacct accagaattc cgacggctcc tatagctttg tccgcaacaa tacactgggg
    14701 ctgtccggcc agctttcggt agaccagaac atttggttta cggggggtaa gctgtcactg
    14761 acttcttcgc tggattatct caaacaactg ggttccggag gagcgaagca gttcatgtca
    14821 gtccccgtga gcctggagtt gacgcagccg gtcttcggag tgaatacctt gaagtggaac
    14881 cgccgtatag agcccgtacg ctatgctgag gcaaaggccg agttcatttc agctacggaa
    14941 gaggtgacga tgaaaaccat cacttatttc tttgagttgc tgctggccaa agaatcgctc
    15001 gctaccgcca tgcagaacaa gacgaatgcc gaccgccttt atgaagtggc catagccaaa
    15061 cgtaaaatgg gacagatatc cgagaatgat ttgttgcagc ttaaactgaa ttcattgcag
    15121 ggcaaggccg acgtgactga ggcagagagc aacctgaatg caaaaatgtt ccagctccgt
    15181 tctttcctcg gggtgtccga gcaggaaagc ctgaatccgg tgttgcccgc cactgttccc
    15241 gatataaaga tggagtatga ccgtgtgctg aacaaggcac tggaacgcaa ctcctttgca
    15301 cagaacattc gccgccgcca gctcgaagct gattatgaag tggcaacggc acgcggaaac
    15361 ttgcgcagca tcgacctctt tgccagtgtg ggctatacgg ggcagaacca tgaattctct
    15421 tcagcctacc gggacttgct tgataatcag attgtgcagg taggcgtcaa gattcctatc
    15481 cttgactggg gcaagcgccg cggcaaggta agggtggcaa agagcaaccg tgaagtggtc
    15541 ttgtccagaa tccgtcagga acagatggac tttaatcagg acatcttttt gctggtggct
    15601 aacttcaaca accaggcgca acagctggac atagccgaag aggcggatgt cattgctgag
    15661 aagcgttaca agaccagtgt agagaccttt atgataggta aaatcagcac cctggacctg
    15721 aacgatgcac agaactctaa agacgaagcc cgtcaaaagc atatttcaga gctgtactac
    15781 tattggtatt acttctatca gctccgcagc ttgacccttt gggattttga acgcgatacg
    15841 gaattggaag ctgattttga agaggtggta agaggataag tcgacgggtt gcaagtgata
    15901 agttatgaat tatttgccgg taaaagtacc gtatatgcga tattataggt aaataactta
    15961 taacttatca ttcataactc tgctttttta cttatttttg cgggaaacaa actacaattt
    16021 ttatgatact gataatagac gacgatagtg ctgtgcgctc ttccctcagc tttatgctga
    16081 agcgtgccgg atatgaggtg aaaacggctc cgggccctcg cgaagctatg gatatagtta
    16141 gggccgaagc tcccgccttg attttgatgg atatgaactt cactctttcc actaccggag
    16201 aagagggact taccttattg aagcaggtaa aggtgttccg tcccgatgtg cccgttattt
    16261 tgatgacggc atggggaagt atccagcttg ccgtgcaggg tatgcaggcc ggcgcattcg
    16321 atttcataac caagccttgg aacaatgctg ctcttttgca gcgcatcgag acggcccttg
    16381 aacttacggc cgccccgaaa gaggtgccgg aagagcagac taccgcattg aatcgcagcc
    16441 atattatagg taagtccaaa gggctgatgg aagtgctgaa cacagtggct cgcatagccc
    16501 gtaccaatgc ttcggtgctg attacgggcg aaagcggaac gggcaaggag ctgattgccg
    16561 aagccatcca tatcaacagc caacgcgtga agcagccctt tgtcaaggtg aaccttggtg
    16621 gcatctcgca gagcttgttc gagagcgaga tgttcggcca taagaaaggg gcgtttaccg
    16681 atgccagtgc cgaccgtata gggcgttttg aaatggcaaa caaaggtacc atcttcctcg
    16741 acgagattgg tgacctcgac ccttcctgcc aggtgaaact gctgcgcgtg cttcaggacc
    16801 agacattcga agtgctgggc gatagccgtc cccgcaaagt cgatgtgcgc gtcgtttccg
    16861 ccactaatgc agacctccgc aagatggtgt ccgaacgtac tttccgtgaa gacctttttt
    16921 accgtatcaa cctgattacc gtaaaactgc cctccttgcg ggagcgccgt gaggatatac
    16981 ctttgctggc acgtcatttt gccgaccgtc aggcagaggt gaacggcttg ccgcgtacgg
    17041 atttctcggc cgacgctctg aatttccttt cccgcctgcc ttatccgggc aacattcgtg
    17101 agttgaagaa tctggtggag cgtaccattc tggtcagcgg caagccggtg ctggatgcca
    17161 cggatttcga tgcccaatat ctgcgtcacg acgaaccggc caaagctgcc gaaggtactt
    17221 cttttgcagg tatgaccttg gatgaaatag agcggcagac tatcttgcag gcgttggaac
    17281 agcataaagg gaatctcagt caagtggcag tgtcattagg catcagccgc gctgcgcttt
    17341 acagacgttt ggaaaaatat aatattcaag tcccgtgcgc ataaaattct ttttcttcat
    17401 acttgtcctt tttctgctcg gtctgggtgg aatgctggta tatctgctga gtgggaagcc
    17461 ttctttgtat ctgtacgtat tggaggggct catcgggttt atccttatct atctgatagt
    17521 attctataat aagatagtga agccgatgaa taccatcggc agcggtatgg agttgctgcg
    17581 cgagcaggat ttcagtagcc gtctcagccg ggtagggcag tacgaggcag accgcattgt
    17641 gaatatcttt aaccgaatga tggagcagct caagaatgaa cggttgcgca tgcgcgagca
    17701 gaatcacttc ttggatttgt tgattcaggc atctccaatg ggggttatta tcctgacaat
    17761 ggacgatgaa gtgtcgcaac tgaatccgat ggcggtaaag atgctcggtg tccgtatgga
    17821 ggaggcgatg acaaaacggc tggaccagat ggactccccg ttggctgccg aactttcgtc
    17881 tattcccaaa gacgagacgg cggtggtccg tctcaatgat gcgaatattt ataaatgcac
    17941 ccattcttct tttattgaca gagggttcaa acatcctttt ttcttgatag agcgtatgac
    18001 ggaagaagtg atgcgtgccg agaagcgtgc ctatgaaaag gtaatccgca tgatagctca
    18061 tgaagtgaac aataccactg cgggcatcac ttccacactc gatacagtgg agcaggcact
    18121 ttctacagaa gatgatatgg aggacatctg cgacgtgatg cgcgtttgta cggagcgttg
    18181 tttctcgatg agccgtttca ttacccgttt tgcagatgtg gtaaagatac ccgaacctac
    18241 cctggcaccc gtccagctga atgagttggt gtccatgtgc aagcgtttca tggaaggaat
    18301 gtgcaatgac cgcaatatag agctacgtct ggaatgcgac ccagaggtgg gaatggtgcg
    18361 tatggatgct tctctttttg agcaggtgct tgtgaatatc atcaagaatg ccgccgaaag
    18421 tatagagggg gacgccggag aaaacggaca gcaaggtgag ataatagtaa ggaccactgc
    18481 ccccgcttct gtcgaagtcg ttgacaatgg tccggggata agtaaagaga ccgaagctaa
    18541 actcttcagc cccttctttt ccaccaagcc gaacgggcag ggaattggcc tggtgtttat
    18601 ccgggaagtt ttgagccgtc atggttgcac gttctccctg cgtacctaca gcgatggatt
    18661 gacccgcttc cgtatactat ttaattgaaa attgaaagtt ttacctttca cctttcaatt
    18721 tctgctttta aagaattctt ttgcatattc gtccaatatc cttttaatgc cttggccgat
    18781 ggtcgcatag tctttctcgt ccagattggc gagtgaggcg cgcacgctcc attcggggcc
    18841 gtcaaaacca ccgccgttca gcagcaccag agaggtttct ttggcaaggc ggaagactac
    18901 gttcagcggg ctgtaggtac gtttcagata ttctacaaag tcgtccccat agaacttctt
    18961 tgcccaaacc agcatgtcga tttctgtata ataacctaca cgcaacgggt cttccgtcag
    19021 cgtgaaaccg gtattctccc aaagggcatg caatcggcgg cggataatct cctgcatctt
    19081 ttgcttgtat ttgttttcct tgtccagcag ggcaaaggcg gcgaaaaggc ccatctgcat
    19141 ctgttgtggc aatgacagtc cggcggtatg gttcagtgcc acctggcgac tgtcggcaac
    19201 catacggtcg ataaacttca gtttttcagg ttccagagtg agggtggagt agcggcggtg
    19261 cagaatctcc cgtttctctt tcggcagttt ggctatcagc ttgtcgaaca gattgaattc
    19321 gtgcagggcg atgaccgcat tgcgccatcc ggtggcaccg aagtatttgg agaatgaata
    19381 gacgcaaagc gtattgtagg gaatttctgc catgaacgaa cggaagtgcg gactgaatgt
    19441 accgtatacg tcgtctgtaa taatcatcag attagggttg tcatttctga cgatactcac
    19501 gatgcgcgcc attgtatccg gactgagtgt gtagctgggc ggattactgg gattggtgac
    19561 aaagagggcc ttgattttag ggcttttcaa gcggtctatg tcttcgtcgc tgtactgcca
    19621 gaggtgcatc ccttcgttat tcatgcggtt ggcatgtatt ttggtcactc gaaactggta
    19681 gcggctgagt tgtgggattt caatataggg ggtaaaggca ggaaccatga ggacgatgcc
    19741 gtcccctttg ttcagcagga agttttcctg cagggagtcg aagatgtagc acatggcggc
    19801 tgttccacct tcggtggcaa acaggtcata ggcaccccgg ggaggacggt tgtcgcacat
    19861 ctcttgcgaa aggtaatctt gcacaaggat ttccgtaaaa tgaaggatgc ggtcgggcac
    19921 gggatactgg tcgcctacaa tgctttcggc ccattcgtgt acaaggctgt cggggtcggc
    19981 ggcatgctgc atcagcaggt agttgtaggt ttgttccagc aatttggcgc ccggtgcgtt
    20041 attgttcttt ttcaggaagg cttcgaagtg ggaggcaatg cctttttttt cggggatgcc
    20101 tgcaatgccc tcgggcaaat ccatgatgcg gcggcactct tccaggccga agcttcccaa
    20161 taggaagaag gcttcgcgtg gagcggttgc aatccagttg gggttgccgc gccctgcgtt
    20221 cagcatggta cgggcggttt tcttcagact ctcgtctgcc atgtctatca ggcggttctt
    20281 cagttcgaaa ggactgatag attccatttt cttttctaaa agttttgtat ccataagctc
    20341 aagtttaggc tcgttattta ttgttttcag tcattcggtg aataatctct gttcatgtgg
    20401 cggactattt ctttccttgc ttgaaattaa tcgtccgata tatgtttcct tttcgtccga
    20461 cagttgttga atcatcgtcc gacagctgtc ggacgaatag ctattagtga atgggtatat
    20521 agtcgcttgc atttccggca ataattcttt gaatgctccg gattagtaag cattggtaca
    20581 gaatcgtctt atattagcaa aacgatgact acaccccata ttattaataa ggtattgccc
    20641 acggcatagg tcacggtgta tcccagagca ggtgtctcac tctcaacggc atcctgcacc
    20701 gcgcctaaag cggccgtagt ggtacgtgcc cccgcgcaga cgcccaaagc cagtgccgga
    20761 tggaacttga aaacatacct tgccagcagc aagccgataa tcagcggcag ggtggtggcg
    20821 gctgctccca ccagaaacag gctgatacct acgtcgtgga agccctgcac gaaactggga
    20881 cctgccgaaa tgcccactac cgcaatgaac atgttcagac cgacattgtt caacacccat
    20941 tgtgaaggtt cgggaatgcg cccgaaggtg gggtgcttac tgcggagcca gccgaagaac
    21001 aagcccgcaa tcaatgcgcc gccgcttgtg ctcaagctga tggggatgcc gccgatatgg
    21061 acggaaagtg ctccgaacaa acctccgaca aggataccaa ggcctacgaa tatcatatcc
    21121 gtctggttgg tagggcggtc tatatacccc agacgtttgg ctgctgcttc cacttcctgc
    21181 ctggtaccta ccacttcgat gacgtcgccg gcatctacta ccgtttgtgc cagcacggga
    21241 atggatattc cggcgcgctt gatgctccgg atactgacac cgtgcatgaa cttttccctt
    21301 cggataactg caaccgtctt gccggcaacc gtcttgcgtg tgattgtaac cggtaacttt
    21361 tcggcaggaa aatccaggag ctgggcatct tgtacttccg gccctatcca gctttcttcg
    21421 cctatgatgt attcgcggcg tccgcttagc actacttcgt ctcccggctc tatctgtatg
    21481 ttcatgctga cttccaccac aactccggat ttgcggaggc gttccacaaa tagacgtttg
    21541 tcgtgctgcc ggaagtagac ttccaggtca atcacccgct ttccattctt gaaccattcg
    21601 ttttcgaccc ggtaggcacg gaaagtgacg gggcgtgccg ccggcatgaa tcccggttcg
    21661 tcagccagag agctgcccat tttcgcctcc agctccttgc aggcggcttt caccttttcc
    21721 agcccgccca gcatcttggg accgatggat gataggaccc atgccgagcc tgccgtaccg
    21781 aaaatgtagg tgacggcgta ggatacggga atgatgttga cgtaactttg tcgttgggcc
    21841 tcgtccagtc ccatattggc catggtgtct tctgccactc cgatgacggc ggagatggtt
    21901 tgcgaaccgg ccagcagtcc ggcagcttca ccggcattgt agcccatcat cagggccagc
    21961 agccaggtca ctaacagtac ggatacacac atcagtacgg caaagcccac ttggggcaat
    22021 ccgtcctttt tcagtccgcg gaagaactgg ggacccactt tatagcccac ggcaaaaagg
    22081 aaaagcagaa aaaataccga ctttatcgga cccggtacgg ctatattcag ttgccctacc
    22141 agtacgccta caagcagtac actggtcact gtgcccagcg taaacttacc gatacgcagt
    22201 ttccccagcc agaatcccag gaatatagtg aggaaaatgg caagttcggg gcgttccctg
    22261 agctggttga aaatccattc cataatcaag ttgtttaggt tatatattgg ttgttccgat
    22321 gctttctgga gcgtcgtttc gctatacaac ggcttttaac gggaagtgtt ttgtacaaaa
    22381 ggagtttttt agaacattta ttccgtaaaa ccgaacttta agaaaaagtt ttcttccgta
    22441 cctttgccat ccaaattagg taaaacaagg tatgaagttg ttttttaggg tatttctgct
    22501 tatccagctg gttactcttc cattgagagc acaatatatg gtgcaaggcg ttgtcaccga
    22561 ttcgttgacg aaggagccgt tgccttatac gtcagtttat ctgaaaggaa ctacggaggg
    22621 agggatgacg gacaataacg gccgtttttc cttcaagacc tatcgcccgg aggccacgct
    22681 ggtcatttcg gccgtgggat ataatgaata tgtccggctg attcatcctg caaagtcttc
    22741 taagttcaat atagcccttt cgccagccac ttatgcactg gatgaggtgg tggtgaagcc
    22801 gaagcgtgaa cggtataaga aaaaggataa tcccgcagtg gagtttgtac gcaagatgat
    22861 agagcatcgg gatgactact cgcccgacga acgcgacttc tggaaacgtg accgctatga
    22921 aaagatgact tttgctatca ataacttcga cagcttgaag caacagaagt ggctttaccg
    22981 taagttcaag ttcctgacgg attatgtcga tacctctgcc gttaccggca ggccggtatt
    23041 ggccatctcc aaccgtgagt tgcttgccac agactattac cgcaagtctc cgcatagccg
    23101 gaaacagtgg gtcaccgccc gcaggcaggc aggagtggac gaaatgcttt cgcagcaggg
    23161 tatggaacag gctatcagtg tcaccatgac cgatgtagac ctttatgaga acaacatcac
    23221 cttgttcacc aataagtttg tcagtccgct atcctccctt gggccgtctt tctacaaata
    23281 ttatctgatg gatacgctta ccgttgccgg aaagccttgt gttgacttga catttgtccc
    23341 tttcaactcc gagtcgttcg gttttacggg acatttatac gtcatgctgg acagtaccta
    23401 ttttgtaaag cgtgccgtca tgaactttcc tcagaaaata aatctgaact ttgtggacta
    23461 catgaagatt gaacagaatt ttgaccgcgc ggaggacggt acgaggcagt tgctcaatga
    23521 gagtatcact acggaattca agttggtgga caatagtgac ggtatttatg ccaagcggga
    23581 tgtgtattac agaaactatc agtatgaacc ggatgacaag gctctgcagg ctttccgaaa
    23641 accggaaaag gtgattgaag agacatcggc ttccggctat tcggaagcat attgggatgc
    23701 caaccgccag gtggaggtca gcaagaaaga gacttcggtg gacaagatga tggcccagtt
    23761 gcgcagctat cccgtttatt tctggacgga gaaagtgttg aaggtgctgt tcacggggta
    23821 tattcccgct ccgaaggaaa aagaaccttt gttctatatc ggtatgatga ataccactat
    23881 cagcggaaat acattggaag gggtgcgctt gcgtgccggc ggtatgacga cggcatggct
    23941 caatccgcat ttgttcggca ggggctatat ggcatacggt tttcgcgacc atcgtgtaaa
    24001 gggactcgcc gaactggaat attcttttca taggaagaag gaatatgcca atgaatttcc
    24061 tatacattcg ttgaagctcc gttacttgtc agacgtcaat caatatggac aacactatct
    24121 ttataccagt caggataatg tttttcttgc cttgaaacgt cagaaggatg accgtatcgg
    24181 ttatcagcgg aaggcgga
//
