LOCUS       c00057_gnlPro..        13001 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EBJCHCDD_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 01:53:32
            Original ID  :: gnl|Prokka|EBJCHCDD_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13001
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13001
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3001]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3001
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13001
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13001
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..286)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 57.3; E-value: 4.7e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_1"
                     /sec_met_domain="Fer2_3 (E-value: 1.7e-18, bitscore: 57.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRF"
     CDS             complement(320..1105)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.4e-14, bitscore:
                     43.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.7e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYEEITDVSPYENPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIG
                     ECNFSDHGANRLGASALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAAAEKAV
                     QEKIDWMMNIKGKKSVDSIHKELGHIMWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELF
                     IPGDKEGMNVELDKAIRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDE
                     NYFYVACWEYQGSDEKEPVLLKEPLVYEAIKVQTRNYKS"
     CDS             1127..2191
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="LCNDIFTQTVDSFGEVKEYGKTGVVHAEALVAAFFGSAAGNVTRN
                     EVTECRITAFQVVVAVFLGNIFSLQCTFLQFLGIFQLLRNPDTTIVTQRFGHQSQLRLL
                     VTVNRDTSGVNLYVSRVGKPGTFTVASHCCRAVTCHCIGRKEVGIAVTTGSDYHSVGGK
                     TFQFTGNEVLCNDTAGTSVNEDNVFHFVAGIQFHSAYVHLAAQCRVCTQQQLLSGLTLG
                     IESTGYLSTTERTVVQCTAVFAGERNTLCNALVDNIVGYFSQTVNVGFAGTVVATLYCI
                     VEQTVYRVTVVLVILSSIDTTLCSDGVCTARRVLDAEVEYSETHFAQRGGSTGTGKSGS
                     YYDDVQTTFVGRVY"
     CDS             complement(2303..3001)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.5e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(3164..3934)
                     /locus_tag="ctg57_5"
                     /transl_table=11
                     /translation="MIFMLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEY
                     IVYWFTELPLICEERYKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKY
                     IEMKCQELVYILTCYYPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYT
                     TTTFRRLFKNMYGVPVYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCK
                     DSFGDTPRALRKRSANGEKISIICKEQGKDQEDE"
     CDS             complement(4310..4672)
                     /locus_tag="ctg57_6"
                     /transl_table=11
                     /translation="MHSLVHTGNSHGTSPQGRRSYHIPFRILYTERGGKGKSRRRMSGR
                     KRRAAFMAICMHSVGIFIIRTLTVHQIFHSISHNKSPRYTCTYVDRIFQQTLIMFYPSG
                     NRHRHRNTDSNIGLRT"
     CDS             complement(4857..6470)
                     /locus_tag="ctg57_7"
                     /transl_table=11
                     /translation="MKKLFTIIICICAVTAQAQKPNNEALRKLQMAEFAITNLYVDKVD
                     EDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVIQPV
                     SNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVDDQL
                     YFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLILDL
                     QGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVDEYS
                     ASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRCIQK
                     PYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRTVYG
                     GGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFNEKF
                     EIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMNSTN
                     QSVQQALKVLNEGIYSTIIQ"
     CDS             complement(6502..6900)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg57_8"
                     /sec_met_domain="CTP_transf_like (E-value: 7.1e-10,
                     bitscore: 29.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSRALTFIDEIVIGIGINENKNTYFPLEKREQMIRDYYRNEPRII
                     VQSYDCLTIDFARQVDASLIIRGIRTVKDFEYEETIADINRKLTGIETILLFTEPELTC
                     VSSTTVRELLQYGKDISMFIPEGMEIRD"
     CDS             complement(6957..8873)
                     /locus_tag="ctg57_9"
                     /transl_table=11
                     /translation="MTLPLEEADNNITESPVSSVEYTDDNIRHLDDMEHIRVRSGMYIG
                     RLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIEDSLRVSVRDYGRGIPQGKL
                     VEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSSRFEVRSYRDGKVRIAIFEKGTL
                     LSDVTEDSTEESGTYIFFEPDATLFLNYSFQNQFVETLLRNYTYLNTGLTFIYNGQRIV
                     SRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTNQYGEEYYSFVNGQHTTQGGTHQ
                     TALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMFESQTKTKLGSNNMWPAAP
                     QEHKPAGPTVNKYVGDFIKTEVDNYLHKNPLVAEVMLQKIQDSEKERKAIAGVTKLARE
                     RAKKANLHNRKLRDCRYHLSDGKGKDQETESCIFITEGDSASGSITKSRDVNTQAVFSL
                     RGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNKVIVATDADVDGMHIRLLI
                     ITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEERVKAIEELGPNPEITRFK
                     GLGEISPDEFKHFIGKDMRLEQVSLRKTDLVKELLEFYMGKNTMERQNFIINNLVIEED
                     LAS"
     CDS             complement(9009..10145)
                     /locus_tag="ctg57_10"
                     /transl_table=11
                     /translation="MAITIKKVTTRRELERFIRFNYLLYKNNPYSVPDLFDDMLNTFNK
                     KKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTWNKKEVRFGWIDFIDDAEVSDA
                     LIRTVEEWGKERGMTHIQGPLGFTDFDAEGMLIEGFDQLSTMATIYNYPYYPQHLERMG
                     FEKDADWVEYKIYIPDAIPDKHKRISDLIQRKYNLKVKKYTSAKKIAQDYGQAIFELMN
                     EAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITDADDQLLAVGISMPSLAEALQK
                     AHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQNKGVNALLFSDLIPVYQQLGF
                     EYAESNPELELNGKVQAQWEYFKTEQHKRRRCFVKGIK"
     CDS             complement(10296..11330)
                     /locus_tag="ctg57_11"
                     /transl_table=11
                     /translation="MKVLYPVCTIFVLKIDMPMDILFLVGGLLLILLGANGLTDGAASV
                     AKRFHIPSIVIGLTIVAFGTSAPELTVSISSALKGSADIAIGNVVGSNTFNTLMIVGCT
                     ALFAPIAITRNTLKREIPLCILSSIALLICANDVFLDGSGENILSITDGLLLLCFFAIF
                     LSYTFAIAKRDGSMKEPEKEHLQEEDEIRLLPAWKSALYILGGLAGLIIGGNFFVDGAS
                     GIARGLGVSESIIGLTLVAGGTSLPELATSIVAALKKNPEIAIGNVIGSNLFNIFFVLG
                     CSASITPLRLTGITNFDLWVLVGSSILLWLFGIFFGKRIITRVEGSILILCYIAYTAVL
                     IYNL"
ORIGIN
        1 tgaaacgacg catataaatc tggcaagtcg tagcgccggt tgcaggaccg tgggggtgtc
       61 cgttgatgta gagcgaacac ataccgcaga taccttcgcg gcagtcgtgg tcgaatacaa
      121 ccggttcttt accttcagaa atcagctgtt cgttcaggat atccagcatt tcgaggaatg
      181 aagtatcgcc cgggatatct ttcatttggt atgtttcaaa agcgcctttt gctttcggac
      241 ccttctggcg ccataccttg agcgtaaatg atatattttt atccattttc tttaattctt
      301 taaatgttca acttcccgat tagctcttgt agttacgagt ctgtaccttg attgcttcgt
      361 aaaccagcgg ctctttcagc aataccggtt ccttttcgtc agaaccctga tattcccagc
      421 aagccacgta gaagtagttt tcatcgtcac gcttggcttc gccttcttca gtctgatatt
      481 cttcacggaa gtgaccgccg cagctttcgt tacggttcag tgcatcgtaa gcaaccagct
      541 cgcccatagt gatgaagtcg tacagacgga tagccttgtc gagttctaca ttcatacctt
      601 ccttgtcgcc cgggatgaac agttctttct cgaactcctt gcggacttct ttcagcttct
      661 tcagaccttc cttcaagcct tcggccgtac gtcccatacc tacatattcc cacataatgt
      721 ggcccagttc cttgtggata gagtctacag acttcttacc cttgatgttc atcatccagt
      781 caatcttctc ctgaacggcc ttttctgcag ctgcaaattc gggcaggtcg gtagagaaac
      841 ggggaactgt aatctggtcg gccagatagt tctggatagt gtaaggcaat acgaagtaac
      901 catcggccag accttgcatc agggcggaag caccgaggcg gtttgcaccg tggtcggaga
      961 agttacattc accgatggcg aacagtccct tgatggaggt catcagttcg tagtcaaccc
     1021 agataccacc catggtatag tggatagccg gataaatcat catcgggttt tcgtatgggc
     1081 tgacatcagt gatttcttca tacatatcga agaggttgcc gtaacgttgt gcaacgacat
     1141 ctttacccag acggttgata gcttcggaga agtcaaggaa tacggcaaga ccggtgttgt
     1201 tcacgccgaa gcccttgtcg cagcgttctt tggcagcgcg gctggcaacg tcacgcggaa
     1261 cgaggttacc gaatgccgga taacggcgtt ccaggtagta gtcgcggtct tcctcgggaa
     1321 tatcttttcc ttgcagtgta ccttcctgca gtttcttggc atcttccagc ttcttcggaa
     1381 cccagatacg accatcgtta cgcagagatt cggacatcaa agtcagctta gactgcttgt
     1441 caccgtgaac cgggatacaa gtggggtgaa tctgtacgta agcagggttg gcaaaccagg
     1501 cacctttacg gtagcaagcc attgctgcag agcagttaca tgccattgca ttggtagaaa
     1561 ggaagtaggc attgccgtaa ccaccggtag cgattaccac agcgtgggcg gcaaaacgtt
     1621 ccaatttacc ggtaacgagg ttctttgcaa tgataccgcg ggcacgtccg tcaatgagga
     1681 caacgtcttc catttcgtag cgggtataca gtttcacagt gcctacgttc acctggcggc
     1741 tcaatgcaga gtatgcaccc agcaacagct gctgtccggt ctgacccttg gcatagaaag
     1801 tacgggatac ctgagcacca ccgaaagaac ggttgtccag tgtaccgccg tattcgcggg
     1861 cgaaaggaac accttgtgca acgcattggt cgataatatt gttggatact tcagccagac
     1921 ggtaaacgtt ggcttcgcgg gcacggtagt cgccaccctt tactgtatcg tagaacagac
     1981 ggtatacaga gtcaccgtcg ttttggtaat tcttagcagc attgatacca ccttgtgcag
     2041 cgatggagtg tgcacggcgc ggagagtctt ggatgcagaa gttgaatact ctgaaaccca
     2101 tttcgcccag agaggcggca gcactggcac cggcaagtcc ggttcctact acgatgatgt
     2161 ccagacgacg tttgttggca gggtttacta atttttggtg agccttataa ttggtccatt
     2221 tctcagccac cggtccttcc ggtattttag aatctatctt agtcataatg caatttacaa
     2281 tttagtcatt tacaatttga atttagcaag cgccgcacaa tgattttgca aagaatacga
     2341 caactaccag agcgaagcag aggacaacga tagtagaata gatgttggag atacatttcc
     2401 aacggttaat ccatactttg ttgttccagc ccaaagactg catggagctc cagaaaccgt
     2461 gagtgaggtg gaaccacaat gcgcccagcc aaacgaggta aagcactacg aataccggat
     2521 tgctgaaggt gttttgaatg tgatagacac cgttggctgc atatgccagc gtgagggtgt
     2581 cagcatgcat gcccatgttg tgcatcaact cgggaagctg cattttagcc cagaagttta
     2641 ccaggtgcag gcccaaaccc acgattacga tgatacccag tacgagcatg ttctgagaag
     2701 cccattccac agtcttgggc ttttccgtaa cggcataacg ttcgctacca cgtgccttac
     2761 ggttctgcat agtcagccag aaagcgtaga tgatgtggat gatgaataag gcagccagac
     2821 ctaccgtagc caccaatgcg taccagtttg ctcccaggaa ctcacaaacc atgttgtagc
     2881 cattagccga gactaatgca accaggttca tcgccatgtg aaatgtcaga aacaggacaa
     2941 gggcgatacc ggtaacgctc atcaccactt tccttcctac agatgaatta cttaaccaca
     3001 taaatgattg aatttaagtt atttaatagt ttgaaaattt gttctatcag gatacttctg
     3061 taaatgtttc gcaaaaatag gagaaatcca gcgataaagc aagcgattaa agaaataatt
     3121 ccgtaatccg gcagaatgcg aagtttacgg acaagtaaaa ggtttactcg tcctcctggt
     3181 ctttgccttg ctctttgcag ataatggaaa tcttttctcc gtttgctgaa cgttttctca
     3241 gggcgcgggg cgtgtctccg aaagagtctt tgcagaagtg ggcaaagtgg gatagggaat
     3301 caaagccata gcgggcgctg atgactgaaa tgcgttgttt ggtgtattgc aggtcgttca
     3361 gaattccttc acgtttcttg tccagaatcc attcatagac cgggacccca tacatatttt
     3421 taaacagacg gcggaatgtg gtggtggtat atccaccgag gtgggcaaac tcttccacat
     3481 tcttcacctt gtcgtagttc tgcatgacga aatattggaa gctttccgta taagtgctga
     3541 tggggtagaa gaatgtactg atttggtgta gcggatagta gcatgtcaat atgtatacca
     3601 attcctggca tttcatttca atgtatttgc tgcacgcata gggttgctcg ttgaggtagc
     3661 aggcaaggct tttcaggagc ccttcgagca tggaaatcgc ggtaagcggg gtataagtca
     3721 agggggcttc cgagcgtttc agtatctcct tgtagcgctc ttcgcaaatc agaggaagct
     3781 cggtgaacca atacacaata tattccactt cggtcaaagc caggagttct actttggagc
     3841 cgatggcttg caagatgagc tggcggcttt ggagagtggt gcccggatat tcgtcactgt
     3901 ttacaagtaa ttcacctttc agcataaata tcatgctgtt ctgtgtgcac ttttcagcag
     3961 agaaatgttg tcccttgggg tagtggcggt aaaccaatac tccttctgat ttttggggac
     4021 ataccataca atcaatctgt cggttgcagc aagtttccag tctcatgaaa tgattagcga
     4081 attattataa atgtggcaac aaagatagaa tttttttgtg aaaactctat ctatttgtcc
     4141 tatctttgcg tcaaactaat ataaaggact tatgaaaaag gctatttttt ttgtatattt
     4201 tatctgcctt gttgtatccg gtctttcggc acagaattgg gatattaaca ctttgcaccg
     4261 ggttaacagt tgggatggca agtttgtccg taactataat aagataattt cacgttcgga
     4321 gccctatgtt gctgtcggtg ttccggtggc gatggcggtt gccgcttgga taaaacatga
     4381 taagggtttg ctgaaagatg cggtctacgt aggtacaagt gtagcggggg cttttgttgt
     4441 gacttatgga atgaaatatc tggtggaccg tgagcgtcct tatgataaat atcccgacag
     4501 agtgcatgca tatagccatg aaggcagccc gtcttttcct tccggacata cggcgacggc
     4561 ttttgccctt gccacctcgc tcagtgtaaa gtatcctaaa tggtatgtga tagctccgtc
     4621 tgccctgtgg gcttgttccg tgggagtttc ccgtatgaac gagggagtgc attatccgtc
     4681 ggatgtgttg gcgggggctg caatcggtgc tggatgtgct gtggtcaaca tctacgtcaa
     4741 caagtggctg aataagtggc tgttcggaga atgattttag gcgcgaatta cgcggaatac
     4801 gcggagttag ataaactaaa tccgcataat ccgcgcctaa gtttgtttca agtcggctat
     4861 tggataatag tgctgtagat gccttcgttc agcactttta gagcttgctg cacgctctgg
     4921 ttcgtgctgt tcatcacctg gaagtattcg ttcatgtccc ataggtcacg ggctatcaag
     4981 gctttaagtt gtgtcttgat gagcggtagg gattggttgt actgtttctc gtcaaacttg
     5041 attttctctt tgtcggcaag cgtacgtatt tcggcaagga agttatcgtc tatctcgaac
     5101 ttctcgttga aggcttcgaa tttcttgtat ttgttctgca actccttccg gtgcttctcg
     5161 atgtagccgg tagtggcttt gataaccacg cctttggcta cgaggttgcg gtgatagtct
     5221 gtgtactggg tagtgtcgat ggggacgaag aagtcgggca tgatacctcc acctccgtaa
     5281 acggtacgtc ccatacgctt ggtctgtgct ttcagggagt cggcaaaatg gatactgtcc
     5341 gcatgaatca tttctccatg attgaagcgg tctatcagtt cctggttata cttatcctga
     5401 ctgttctcgc cggttaggcg accatcgagg ttggcggtac tgtcgtaagg cttctggatg
     5461 caacgccccg aaggggtata gtaacgggct atggtcagac gaatcatgga accgtccggc
     5521 aggtcgatag gacgctgtac taatcccttg ccgaaggtgc ggcgtcctac taccacgcct
     5581 ctgtcccagt cctggatggc tccggtcacg atttcactgg cagaagcgga gtactcgtcc
     5641 accaatatga tgagacggcc gttcttgaag ttgcccgtac ctttggcaaa gaaatcactg
     5701 cggcgtgcgg cccttccttc ggtgtagacg atgagttctt tttgcttcag aaattcgttg
     5761 gcaaggtcga tggcggcatt cagataccct cctccatttc cttgcaggtc gaggatgagg
     5821 tctttcattc ctttcttttg caggcttttc agggcttctg caaactcttc ggcggtggtt
     5881 gccccgaagc ggttgatacg gatatagccg gttttgggtt gtatcatgta agatgcgtcc
     5941 aggctgagga tgggaatttt gtcacgcttc acggtgaagt acagctggtc gtccacgcca
     6001 cggcgcacga tggtgagttt cacttccgag tctttcggtc cgcgcaggcg gctcataata
     6061 tcttccgtgc tcatttttac tccggcaatg gcgctgtcat tgacggctac gatacggtcg
     6121 ccggcaagga tgcccacctt ctcggaaggt ccgttgctca cgggttgtat cacaagcagg
     6181 gtatcttcta tcatctgaaa ctgtacgccg atgccctcga aattgccttg caacggctcg
     6241 ttcatcttct tcacttcttc ggcgttgttg taggtggagt gcgggtcgag ttgtgccagc
     6301 atcttgatga tggcttcttc caccagcttg tcttcatcca ccttgtccac ataaaggttg
     6361 gtgatggcaa actctgccat ttgcagtttg cgcagggctt cattgttcgg cttttgcgct
     6421 tgtgccgtca ccgcgcatat acatattata atagtaaata gttttttcat catttccatt
     6481 ttaatcccta atcctttatc cttaatccct aatctccatt ccctccggta tgaacatgct
     6541 tatgtccttg ccgtattgca gcagttcgcg cacggtggtg gaactgacgc aggtaagttc
     6601 cggctcggtg aagagcagga tggtttctat gccggtcagt ttgcggttga tgtcggcaat
     6661 ggtttcctcg tattcgaaat ccttcacggt gcgtatgccg cgtattatca gactggcatc
     6721 tacctgccgg gcaaagtcga tagtcaggca gtcataggac tgcacaatga tgcgcggctc
     6781 gttccggtag tagtctcgta tcatttgttc gcgcttttcc aaggggaaat acgtattctt
     6841 attttcattg atgccgatgc ctatgacgat ttcgtctata aaagtcagtg cacggctcac
     6901 taccgaagag tgtccgatag taaacgggtc gaatgttccc ggaaagatag ctcttctcat
     6961 gatgccaaat cttcttctat aaccaagttg ttgataataa agttttgtcg ttccatggta
     7021 ttcttaccca tgtagaattc cagcagctct tttacgaggt ctgtcttgcg cagggacact
     7081 tgttccagac gcatatcctt gccgataaaa tgcttgaact cgtcgggcga gatttctccc
     7141 agacctttga atcgggtgat ttcggggttg ggacccagtt cttcaatggc tttcacacgt
     7201 tcctcctctg tatagcaata acttgtcttc tttttgttgc gcacgcggaa gagaggggtt
     7261 tgcaggatat atacatgccc tttctttatc aggtcgggga agaactgcag gaagaaggtg
     7321 atgatgagca ggcggatgtg catgccgtcc acatcggcat cggtagctac gatgactttg
     7381 ttgtagcgca gtgtctctat gccgtcttct atattcaagg ctgcttgaag caagttgaat
     7441 tcttcgtttt cataaactac tttcttggtg agtccgtagg aatttagcgg tttaccacgc
     7501 aggctgaata ctgcttgggt attcacgtcg cggctcttgg tgatggaacc gctggcggag
     7561 tctccctcgg taatgaagat gcaggattcg gtttcctggt ctttgccttt accgtcactc
     7621 aagtggtagc ggcagtcgcg cagcttgcgg ttgtgcaggt tggctttctt ggcgcgttcg
     7681 cgtgccagct tggtgacgcc ggcaatggct ttgcgctctt tctcggagtc ttgtatcttt
     7741 tgcagcatca cttcggccac aagcgggttc ttgtggaggt agttgtccac ttccgtcttg
     7801 atgaagtctc ctacgtattt gttcaccgtg gggccggcgg gcttgtgttc ctgcggcgcg
     7861 gcaggccaca tgttgttgct gcccagtttc gttttggtct ggctctcgaa catgggttcc
     7921 tccacgtcga tggcaatggc ggctaccagt ccgttgcgga tgtcggcata ttcctggttc
     7981 ttgttgtaga actccttgat ggtacgggca atgtgttcct tcaaggcagt ctggtgtgtg
     8041 ccgccttggg tggtgtgttg cccgttgaca aaggagtagt actcttcgcc gtattggttg
     8101 gtgtgtgtga aggcaatctc gatgtcctct cctttcaggt ggatgatgtc gtaaaggcct
     8161 tcgctggtca tgttgtcttt cagcaagtcc tccagcccgt ggcgggaaac gatgcgctgg
     8221 ccgttgtaaa tgaaggtgag gcccgtattc aggtaggtgt agttgcgcag cagggtttct
     8281 acgaactggt tctggaagga atagttcaag aagagtgtgg cgtccggttc gaagaagata
     8341 taggttccgc tttcttctgt cgagtcttcg gtcacatcac tcaacagcgt tcctttttca
     8401 aagatggcga tacgtacctt gccgtcgcgg tagctgcgta cttcgaagcg gctgctcagc
     8461 gcattgactg ccttgatacc tacgccgttc agtccgacac ttttcttgaa agccttcgag
     8521 tcatatttac ccccggtatt cagtttgctg accgcctcta ccagtttgcc ttgcggaatg
     8581 cctcgtccat agtcgcgtac gctgacacgc agactgtctt ctatagtcac ttctatacgc
     8641 tttccggcac ccatcttgaa ctcgtcgatg ctgttgtcca tcacttcttt cagcaacaca
     8701 tagatgccgt catcgttctg tgagccgtcg cccagacggc ctatgtacat accggaacgg
     8761 acacggatat gctccatgtc gtccaggtgg cggatgttgt cgtcggtata ttccacgctg
     8821 gaaacggggc tctctgtgat attgttgtct gcttcttcca gcggcagggt catattgttg
     8881 ttatcttcca taagtacgtt attccttcat attgcgcatt gcgacaaagg taatgagaaa
     8941 ttcgggggtt cgcaaaaaaa taatgtcttt tatggacttc tgacaagctt atattctgga
     9001 tttagaactt attttattcc tttcacaaag catcttctcc gtttatgctg ttccgtcttg
     9061 aagtactccc actgcgcttg caccttgccg ttcagctcca gctccggatt actctcggca
     9121 tactcgaaac caagttgctg atagacgggg ataaggtcgg agaacaacaa tgcatttacc
     9181 cccttgttct gatactccgg tttcacggca accagcagca aatcgagcat cttgggatat
     9241 ttcttcaaga agatggtctt ggccaggtga taccaaccca taggaagcag gcgcccgtgg
     9301 gctttttgca acgcttcggc gagtgacggc atggaaatgc ctacggcaag cagctggtca
     9361 tcggcatcgg taatcaatgt caccatgcgt aggtcgagga tgggcaggta catcttgacg
     9421 tattggtcaa tctgccgttg gctcagtgca gaatagccat agagtggctg ataggcttcg
     9481 ttcatcagtt cgaagatggc ctgaccgtag tcttgggcaa tcttcttggc agatgtgtat
     9541 ttctttacct tgaggttata cttgcgctgg atgaggtcgg agatgcgctt gtgcttgtcg
     9601 ggtatggcgt cgggaatgta gattttgtac tccacccaat cggcatcctt ctcaaagccc
     9661 atgcgttcca gatgttgcgg atagtaggga tagttataaa tggtggccat ggtgctgagc
     9721 tggtcgaatc cttcgatgag cataccttcg gcatcgaaat ctgtgaatcc cagcgggcct
     9781 tgtatatgtg tcattccccg ttcttttccc cattcttcca cggtgcgaat cagggcatcg
     9841 gagacttccg catcatcgat gaagtctatc cagccgaagc ggacttcctt tttgttccag
     9901 gtttggtttg ccttgtggtt gatgatggca gctacacgtc ctacgatttt accttcccga
     9961 taagccagga aatagtcggc ttcacaaaat tcgaatgcag cgtttttctt cttgttgaag
    10021 gtgttgagca tgtcatcgaa aaggtcgggg acggaatagg ggttgttttt gtatagcagg
    10081 tagttgaaac ggataaagcg ctccagttcc cgtcttgtgg ttactttctt gattgtaatt
    10141 gccatagttg ttcaatattg agaccacaaa ggtaatgcaa actgagagca gaacaaaata
    10201 agcttgctta ttttttatgc cgaggtacag cttgccttat ttaaaaatac gtgataatct
    10261 ttaaaatacc gcgtagggtg tttgtaaatt tgctgttaga ggttgtatat cagtaccgct
    10321 gtgtaggcaa tgtagcagag aatcagaatg cttccttcca cccgggtgat gatgcgtttc
    10381 ccgaaaaaga taccgaacag ccaaagcagg atgctggacc ctacgagtac ccacaaatcg
    10441 aaattggtga tgcccgtcag acgcagtgga gtgatggagg ccgaacaacc cagtacgaag
    10501 aatatattga agagattact tccgatgacg tttccgatgg ctatttcggg gtttttcttc
    10561 aaggcggcta cgatggaggt ggcgagttcg ggcagtgaag tgccgcctgc tacgagcgtc
    10621 agcccgatga tggattcgct gacacccaat ccgcgggcta tgccgctggc accgtctaca
    10681 aagaaattac ctccgatgat gaggccggca agtccgccga gaatgtatag ggcggacttc
    10741 cacgcgggta acagcctgat ttcgtcttct tcctgtaagt gctccttttc cggttccttc
    10801 atacttccat ccctttttgc aatggcaaaa gtataactca ggaaaatggc aaagaagcat
    10861 agcagtaaca gaccgtcggt gatgctgagt atgttctccc cactgccgtc cagaaagacg
    10921 tcgttggcac aaatcagcag ggcgatggac gaaaggatac atagagggat ttcgcgcttc
    10981 agcgtgttgc gggtgatggc tatcggggca aaaagggccg tacaacccac aatcatcagg
    11041 gtattgaacg tattgcttcc caccacattg ccaatggcaa tgtctgcact gcctttgaga
    11101 gcagaggata tgctgacggt gagttccggt gcggaagtgc cgaaggcaac aatggtgagc
    11161 ccgatgacga tggacggtat gtggaaacgt ttggcaacgg atgcggcacc atctgtcaaa
    11221 ccattggcgc ccaaaagaat gaggagcagt cctccgacaa gaaacaatat atccataggc
    11281 atgtcaattt tgagtacaaa gatagtgcaa accggataca gaactttcat gtttgcatga
    11341 aaaagttatg tcgattaggg taggaagtta aaaacattcc gtatgtttga agcatttatt
    11401 gggtatattt gcataattaa agaatcaaat caagaagttt atatatgaag gttatccgtg
    11461 ctttctttct ttgttggctg ttgatgctgg cggacggagt gtcagctcag ttggtagata
    11521 aagtgctcag tgttttaggt gaggatagtg tggggagtgt cacagtggca aggactgact
    11581 ccgattcgat tcaattgtcg ctcatcaggc aggaattgga agcagcccgg ctgaacgaag
    11641 cgaacctgcg gatggaaatg gaacagatga agctggcggg ctatgcggcc gattcggtga
    11701 agctggcatt gcagaaacaa cgcattgatt cgttgcggac ggtgacgcct ggtattccgg
    11761 tggtggtgga gaaggacact ttgttctatc tgtatgccaa gcgtggaggg catacgcccc
    11821 aacagcgagc caaagatgta agcaacgtca tcgaagcatt gggcacgcgt ttcaatctgc
    11881 gtccggactc tgtttattta gagagtacgg atattgttac agacttgatg tatggcgaaa
    11941 aggtcatcat ttcctttacc gatcaggatg ctttgtggga aaactgtacc cgcgaccagc
    12001 tggccgccag caagaggcat gtcgtggtgg acaaactgaa agccatgcag aaggagcata
    12061 gcttgtggca gttgggtaag cgtatcttgt actttatcct ggtgcttgtg ggacagttct
    12121 tcttgttcaa gtttaccaac tggctgttca gaaaactcaa actacgcatt cagaagctga
    12181 aggataccaa gctgaaaccg atctctattc aggattatga attgctggat acgcagaagc
    12241 aggtcaactt gctggtgttt gttgccaacc tggtgcgtta tgtggtcatg ctgttgcagt
    12301 tgctgctgac ggttccgtta ttattctcca ttttccctca gaccaagagc ttggcttata
    12361 cattattctc ctacatctgg aatcctataa aggtcatctt gaatggaata gccgactata
    12421 tacccaatct gttcactatc tttgtgatat gctatgcggt gaagtatctg gtcagactgg
    12481 tgcgttatct tgccaatgag gtgcaggctg aacggctgaa gataaacggc ttctatccgg
    12541 attgggccat tcctacctat catattgtgc gcttcttgct ttatgcgttt atgattgcca
    12601 tgatttaccc ttatctgccg ggttccaagt cgggagtctt ccagggaatc tccgtgtttg
    12661 tcggcttgat tgtttcgctc ggttccagta cggttatcgg caatatcatt gcaggactgg
    12721 tcataaccta catgcggcct ttcaagctgg gtgaccgcat caagctgaat gacactactg
    12781 gcaacatcat tgagaaaaca ccgctcgtca cccgcatccg tactccgaag aatgaggtgg
    12841 tgaccattcc gaactctttc atcatgtctt cccatacggt caattacagc cagtctgccc
    12901 gtgagtatgg attgattatc cattcggagg tcagtattgg ctacgatgtt ccgtggcgga
    12961 agacacatca gctgttgata gaggctgcat tgaatactcc t
//
