LOCUS       c00073_gnlPro..        15007 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NPLAGMNC_73.
ACCESSION   c00073_gnlPro..
VERSION     c00073_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:28:19
            Original ID  :: gnl|Prokka|NPLAGMNC_73
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15007
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15007
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1948:5007]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1949..5007
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15007
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15007
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(355..1176)
                     /locus_tag="ctg73_1"
                     /transl_table=11
                     /translation="LFSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHY
                     HHFGLWYAWTKTTFEGNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAE
                     KVAMNERLEINIGTTSLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTA
                     EMLTSEGLSRDEADGSRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKP
                     AGDVMWNFSPTKQKAFTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             complement(1334..1543)
                     /locus_tag="ctg73_2"
                     /transl_table=11
                     /translation="LYLEISSNLWLLSCKGMLNPHITQTIKEIFHQLERCLLAGFICIR
                     YHKRIVRNEKISFFCSRYRQGLAG"
     CDS             complement(1652..1924)
                     /locus_tag="ctg73_3"
                     /transl_table=11
                     /translation="VQNHEQDNDHTQNKHVLRSPFNTFRTSVDGITVVTASLTILQSQD
                     NSIHEVHDYTCSQHQCTEQSIPVRTQQTANHVIRFTRKYCRNVHT"
     CDS             1949..2242
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_4"
                     /sec_met_domain="SucD_FumR (E-value: 5.9e-29, bitscore:
                     92.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYLIWFVALWFH
                     LTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGVGA"
     CDS             complement(2260..2499)
                     /locus_tag="ctg73_5"
                     /transl_table=11
                     /translation="VCTTGRVLNTEIQYIESHFSQRGSSRSTRQTSTYYNYVQTTFVCG
                     IHQFLVIFIICPLLSQRALRNFRIYLSHNVLFSN"
     CDS             2549..2668
                     /locus_tag="ctg73_6"
                     /transl_table=11
                     /translation="MVTRFIVCSTIQSKVVTTVPAKQTSIVWLKCQTLLSTSA"
     CDS             complement(2719..3081)
                     /locus_tag="ctg73_7"
                     /transl_table=11
                     /translation="VDLHHTRISKVSPFLVALPCSRTVRRHRVSRQEECIYITTCRNND
                     CVSGKTFDLTGNQITGNNTASTSVNLHNIQHFMACVHLHLSQTNLTAQCRVSTQQQLLS
                     GLTTGIERTGYLSTTE"
     CDS             3091..4224
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 53.8; E-value:
                     5.9e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_8"
                     /sec_met_domain="FAD_binding_2 (E-value: 3e-17, bitscore:
                     53.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.4e-38,
                     bitscore: 122.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VPVKGDFQSKLTLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKD
                     IPEADRDYYLERRYPAFGNLVPRDVASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLG
                     KEVVKQKYGNLFDMYEEITNDDPYETPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGE
                     ANFSDHGANRLGASALMQGLADGYFVLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIN
                     ARIAKLMNVKGKETVDSIHRKLGHIMWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFI
                     PGEANSLNVELDKALRLADFIEIGALMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDK
                     FMYVSCWEYQGEDKDPVMLKEDLNYQFVVPQTRNYKK"
     CDS             4385..4474
                     /locus_tag="ctg73_9"
                     /transl_table=11
                     /translation="MNVWLAKVKNLSYSTTTAVKVSAVCVHCM"
     CDS             4456..5007
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg73_10"
                     /sec_met_domain="Fer2_3 (E-value: 4.3e-09, bitscore: 27.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.7e-12, bitscore: 37.7,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5e-06, bitscore: 18.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIEPWRSAGFPV
                     IRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAACIGCGACAAA
                     CKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTRACEMECPKN
                     ISVSNIARLNREFISAKLQD"
     CDS             5635..5886
                     /locus_tag="ctg73_11"
                     /transl_table=11
                     /translation="MPHFSENPGAAYAAPANHNGIHAILFETLFADFGGSHIAIADDGN
                     LYAGIVFYFTDQCPVCLSCIHLCPGTSVDGKGCDTAIL"
     CDS             5855..6091
                     /locus_tag="ctg73_12"
                     /transl_table=11
                     /translation="MERAAIPQSCSCSAKSTMIRLSASQPKRVFTVTGMFTALTTSRVM
                     SSISGILRSMPAPAPLPATRLTGQPKLISRMSG"
     CDS             6088..6231
                     /locus_tag="ctg73_13"
                     /transl_table=11
                     /translation="MSGFANLRGFDHCRNITAIYLYGDRTFFIRHIQLLLCFIYTADQG
                     VC"
     CDS             6269..6406
                     /locus_tag="ctg73_14"
                     /transl_table=11
                     /translation="LHINRKEISVTSSIGAKKTGRSPKSIVPIFIFILSMTGTKVLISC
                     "
     CDS             6636..6728
                     /locus_tag="ctg73_15"
                     /transl_table=11
                     /translation="MVFDHDFDALRNGYPCNSSRILFLPLRTNQ"
     CDS             6729..8000
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_16"
                     /sec_met_domain="Peptidase_U32 (E-value: 3.4e-69, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKNLNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSR
                     SSNNFTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAAD
                     VAAMNYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQ
                     QITGPKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDS
                     NIELDIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRA
                     YCNGTFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIK
                     YFDKIGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLK
                     VNEKIRPSDRLYKMEKVQLEKVFE"
     CDS             8000..8407
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg73_17"
                     /sec_met_domain="HBT (E-value: 4.7e-09, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 7.3e-10, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(8530..9312)
                     /locus_tag="ctg73_18"
                     /transl_table=11
                     /translation="LNGSSPSLDIPTKSGEQIVRRSDQAGFILSDQIVASFGMAVTDAP
                     WKAIDIPAIRECNIGSYQRASFFCRFNHDRTIRDSGDNPVPPEEIWTVWFCTAGKIGQQ
                     TARFQHFDSRIPMAGRIDTIQAMRQHSNSRKSVVQSVPVGTDIDAVSQSTHDQQVRDHF
                     CQVFYKGFGKLPTIFGRVASTHNTDDTGRIKVSISLKIEKYRGIRTFSQAHRIICISQI
                     ITGNIVFLDKSQLFFRPLQDFRAFDFGSNIAADTRDPS"
     CDS             9319..9519
                     /locus_tag="ctg73_19"
                     /transl_table=11
                     /translation="LFFAEAETFTSEQNPVLAIMRTRNEIHINELASVLEIPVHQLSML
                     LFELEINGKVKALPGNLYKLS"
     CDS             9544..9699
                     /locus_tag="ctg73_20"
                     /transl_table=11
                     /translation="MWEKKRNLYKQLKAVSRQPLTNFVNLKSNTIMKKPHCKDTLVKSV
                     CQAFCR"
     CDS             complement(9770..10666)
                     /locus_tag="ctg73_21"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDV
                     PLEVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             complement(11277..11657)
                     /locus_tag="ctg73_22"
                     /transl_table=11
                     /translation="VSWHYVFNSLFSSFFNHIDNLFQLIGRYLLFFSKKGDHFLVRVLE
                     IVVHHTSHKRPFIFLLWDQRPVFVSISVTFRFHVFLTFQILHNRSECRIRRLRLFILRQ
                     DVFDKTRLDLPDPAHYILFLSC"
     CDS             complement(12014..12364)
                     /locus_tag="ctg73_23"
                     /transl_table=11
                     /translation="MCQPQKVILVATTVIARFKYRIIRQIFQIMTYLSFQQPDKRIHPT
                     DDTNQFANNHVNRMPLADMRTLVYQNLIDLFLGMAVGMQKYQPEKRKRTGRFIQQMYTY
                     VTDQSHFRPPCQ"
     CDS             complement(12343..12564)
                     /locus_tag="ctg73_24"
                     /transl_table=11
                     /translation="VLSVSSSVIRANASTLLKISKAPTTGIKIKYFVLPMLRERFLFIM
                     LIRFFRCSILKLLDKEVTDLLVCANPKR"
     CDS             12719..12823
                     /locus_tag="ctg73_25"
                     /transl_table=11
                     /translation="MPEFPGGQGALLKFLATNVRYPESAVKIWYRGTG"
     CDS             complement(12795..13406)
                     /locus_tag="ctg73_26"
                     /transl_table=11
                     /translation="MTDSGQLLQTESNRNRIFYGYSHIVLYARIPFRHFPDHPDSLPVQ
                     RRIDSTDHFNIFQTSIRVDNERARDTSLYSILLSNSRIFYACCQIFQQRSLSTRKFRHL
                     LHYRKDTTGRIDFFNLPLHDTRGCFFLSTGKPESYRYRIFDINHFAPLFPRRPYRHGVY
                     HTQSLLIQFRTYPTNHFCLRDSPVFSNNERTANPSLYTIF"
     CDS             13422..14975
                     /locus_tag="ctg73_27"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 tcttttttca tctttgttga cttttatgaa gtcaacctat ttcaggacga gacaatcgct
       61 catctatctg ttttaaatga ataaactcca agcattttaa ggtaaaagta gggagacaat
      121 tttatcaaca cccccatgta tccgcccccg acacccggat cttacgctct tatagatccg
      181 ggtgtcgggg gcggatacat gggggtgttg ggtaagtttt attacgtgtt tttcattgat
      241 ttgtagctgt atttacataa aagagccttg tctttgatga tataggagaa caagcccttt
      301 ttccttttct tgtttacctt gccctgcaaa ttgtcagttt gttttagtag aaattcaatc
      361 acgttcgaaa tcggacagca cttctgccgt agtagcgttg atgttcttgt ccaatacata
      421 aatgcggtaa gacaggctca gttctttacc gggttccaag gtgaatgcct tctgcttggt
      481 cggtgagaaa ttccacatga cgtcaccggc aggcttgttg acagttttgt cccatacgcg
      541 taaaggctca ggatagttca ggttggaagg ggaggcaacg attaggatac aggccttttc
      601 gtttccggct ttcccttggt agtagcacca acgggctctc gaaccgtcag cttcgtcgcg
      661 ggaaaggcct tccgaggtga gcatttcggc tgtctgatcg ttccagtctt cgcgcgtacg
      721 gatgcatatg ccgccataac ggtaagcttc catggtgatc gggctggggc tggcgaggcg
      781 gatagtggta tgatagtcga tgtaataacc tggtaaggat gttgtcccga tgttgatctc
      841 caggcgttcg ttcattgcta ctttttctgc gggagaatcg gggtagacca catggtccag
      901 tgtcgcaaca aaaccgttgt cggatacgtg ttcgaagttg cggaagcgaa ctgttccttg
      961 ttttttgtgg agattccaga agtcgatctc gtttccttcg aacgtggttt tcgtccaggc
     1021 ataccacaaa ccgaaatgat ggtaatggtc ggcgggagaa caattggtca tcacttcgcc
     1081 tcccaatgtc ttcaaaggat ggatgaaacc gctgcgttta tagaccgagt caacgccaga
     1141 ggctgggtaa actgtggtat agttgtaaga gaacaacagt ttatctccta tcttatagtc
     1201 taaggttttc cccgtgtcga cgacggaaca ggatgtttcg gaaggctgac aagagcctaa
     1261 gaacagagaa atcaaaaaaa caccaataga aaaaatagca gttttcataa tatgacaatt
     1321 aaataataat cagttatccg gcaagacctt gcctgtatcg gctacaaaaa aacgaaattt
     1381 tttcgtttcg cacaatccgt ttgtgatatc tgatgcaaat aaaaccagcc agcaagcagc
     1441 gttctaattg atgaaatatt tctttaatcg tttgcgtgat atggggattt agcatacctt
     1501 tgcacgataa taaccataga ttggaggaaa tttctaaata caattaaata acttaaatta
     1561 ttatcttatg tggttactta attcttctat cgggaagaag ctgataatga gtatatcagg
     1621 tctttttctc attctgttct tggtgttcca cttatgtatg aacattgcgg cagtattttc
     1681 tggtgaagcg tataacgtga tttgcggttt gctgggttct aactggtatg ctttgctcgg
     1741 tacattggtg ttggctgcag gtgtagtcgt gcacttcgtg tatgctatta tcttgactct
     1801 gcagaatcgt aaggctcgcg gtaacgaccg ttatgccatc aacgctcgtc cgaaaggtgt
     1861 tgaatgggct tctcagaaca tgtttgtttt gggtgtgatc gttatcctgt tcatggttct
     1921 gcactttact cagttctggt acaacatgat gtttgccgaa ctggcaggta ttcatggtga
     1981 cattcatccg caggatggtg cagcgtttat caatttctac ttccagggca atgtcgtgaa
     2041 tacggtgttg tatctgatct ggttcgttgc tctgtggttt cacctgactc acggtttctg
     2101 gtctgcgatt cacacaattg gctggaacaa taccgtttgg ttaagccgtt gggaatgtat
     2161 ctctaaatgg gttgccacta ttatttgtgg cttattcgct gttatcacag ttatcttcta
     2221 cctgaacggt gtaggtgctt aatttcggat attatttttt caatttgaaa ataaaacatt
     2281 atgactcaaa tagattctaa aattcctcaa ggcccgttgg ctgagaagtg gacaaattat
     2341 aaaaatcacc agaaattggt gaatcccgca aacaaacgtc gtttggacat aattgtagta
     2401 ggtactggtc tggcgggtgc ttctgctgct gcctctctgg ctgaaatggg attcaatgta
     2461 ttgaatttct gtattcagga ctctccccgt cgtgcacact ctatcgctgc acagggcggt
     2521 atcaatgcgg caaagaatta tcagaatgat ggtgactcgg tttatcgtct gttctacgat
     2581 acaatcaaag gtggtgacta ccgtgcccgc gaagcaaacg tctatcgtct ggctgaagtg
     2641 tcaaactcta ttatcgacca gtgcgtagca cagggtgtac cattcgctcg cgaatatggt
     2701 ggtctgttgg ataaccgttc attcggtggt gctcaggtat cccgtacgtt ctatgcccgt
     2761 ggtcagaccg gacagcagct gctgttgggt gcttactctg cattgagccg tcagattggt
     2821 ttgggaaagg tgaagatgta cacacgccat gaaatgctgg atgttgtgaa ggttgacgga
     2881 cgtgctcgcg gtattattgc ccgtaatttg attaccggta agatcgaacg ttttgccgct
     2941 cacgcagtcg ttgttgcgac aggtggttat gtaaatacat tcttcttgtc tactaacgcg
     3001 atggcgtcta acggttctgc tgcatggcag tgctacaaga aaggggctta ctttgctaat
     3061 ccttgtatgg tgcagatcca cccgacttgt gtgccggtga aaggtgactt ccagtctaaa
     3121 ctgactttga tgtctgaatc actgcgtaac gatggtcgca tctgggttcc gaagaagctg
     3181 gaagatgcga aggcattgca ggccggaaca aaaaagggaa aggatattcc tgaagcagat
     3241 cgcgactact atctggaacg tcgttatccg gcattcggta acttggttcc tcgtgatgtg
     3301 gcttcacgtg ccgctaaaga acgttgtgat gccggtttcg gtgtaaatag cacgggcttg
     3361 gctgtattcc tggatttctc cgacgctatc aaccgtctgg gtaaggaagt ggttaaacag
     3421 aaatatggta acctgttcga tatgtacgaa gagatcacga acgatgatcc gtacgaaact
     3481 ccgatgatga tttatcctgc attgcactac tcaatgggtg gtttgtgggt agactatgaa
     3541 ttgatgactt ctattccggg gctgttcgca attggtgaag ccaacttctc tgaccatggc
     3601 gctaaccgtc tgggtgcttc tgctttgatg cagggattgg ctgatggtta ctttgtattg
     3661 ccttacacga tccagaacta tctgtctgac cagatccagg ttccgcgctt tagcactgac
     3721 ctgcctgaat ttgtggaagc agaaaaggct attaacgccc gtatcgcgaa gttgatgaac
     3781 gtgaagggta aagaaactgt cgattctatc caccgtaagc tgggacatat catgtgggaa
     3841 cacgtcggta tggcacgcga cgcggaaggc ttgaaagaag ctatccaaat gttgaaagac
     3901 ctgaagaagg aattctggag caatgtattc attccgggtg aagcgaacag cttgaacgtg
     3961 gaattggaca aggcattgcg tttggctgac tttatcgaaa tcggtgcatt gatggcacac
     4021 gatgcgttag accgcgcaga atcttgtggt ggccacttcc gtacggaaca tcagaccgaa
     4081 gaaggcgaag ctatgcgtca tgacgataag ttcatgtacg tctcttgttg ggaataccag
     4141 ggtgaagaca aagacccggt tatgctgaag gaagatttga actatcagtt cgttgttcct
     4201 caaacacgta actacaagaa gtaataatca tcaatcacaa aaattagaat catggataaa
     4261 gatataaagg taacacttaa agtttggcgt cagaaaggtc cgaaagataa aggacagttt
     4321 gagacttacc aaatcgacaa aatcaatcag agtgtttctt tcttggaaat gttagacatt
     4381 ttgaatgaac gtttggttag cgaaggtaaa gaacctatcg tattcgacca cgactgccgt
     4441 gaaggtatct gcggtatgtg ttcattgtat gtaaacggac atccgcacgg accggcaaca
     4501 ggtgcaacaa cctgtcagct ctatatgcgc cgtttcaatg atggtgagac gattacgatc
     4561 gagccgtggc gttctgccgg tttcccggta atccgcgact tgatggtaga ccgttatgct
     4621 tatgataaga ttatccaggc aggtggtttc gtttctgtaa acacaggtgg ggttcctgat
     4681 gctaatgcaa ttcctatttc taaggctgat gcggatttgg ctatggatgc tgctgcttgt
     4741 atcggctgcg gtgcttgtgc tgctgcttgt aagaacggtt cagctatgct gttcgtctct
     4801 gcaaaggtta gccagctggc tcttttgcct cagggtaagg tggaagctgc tcgtcgtgca
     4861 aaagcaatgg ttgctaagat ggatgaactg ggctttggta actgtacgaa cactcgcgct
     4921 tgcgaaatgg aatgtccgaa gaacatctcc gttagcaaca tcgctcgctt gaaccgcgag
     4981 ttcatctctg ctaagttaca agactaatac attatatata tgtatatgga aaagcccgtc
     5041 gtcaatggca acgggctttc tttatgttcg ttcaaaccca caaaaaagcc gcactcccta
     5101 taataaaagt ggatgcggct tttttgttgc tttccagtga aacagtctct cgattccctc
     5161 tctgcaaaga ctttgttaac cttagatcta aaatactatg aaaaaaactc actgcaaata
     5221 taaagtatat ttactgaata cgcaagagtt tgtaattaca ttttattgca aatttgctac
     5281 tttttgtttt aaaattgaca ctgtgtgcgg attcacactg ttattatatc aacaatcgat
     5341 cgattctgac acttgagagt cgctttgaaa tccgtatcct gtatgaaatt tgtcggggat
     5401 ggaatccaga atgtcgaata atgcttccac tgtttccgca cgtagcatgg cgacgcgtgt
     5461 ctgcttgaag tctgcaatac ctttaaacag cggagttgca gccaaatggc ggcgaatgtg
     5521 gagaattccc cggcgctcat ccaaacgttc cacgctttgt tccacctgct ttttcagtat
     5581 gttcagatac catgaaaaag attcggcagg caatgtctcg cctgtatcca gataatgcct
     5641 cacttctctg aaaatccagg ggcggcctat gctgccccgg ccaatcataa cggcatccac
     5701 gccatattgt tcgaaacgtt gtttgcagat ttcggcggaa gtcacatcgc cattgccgat
     5761 gatgggaatt tgtatgcggg gattgttttt tacttcaccg atcagtgtcc agtctgcctc
     5821 tcctgtatac atctgtgccc gggtacgtcc gtggatggaa agggctgcga taccgcaatc
     5881 ctgtagctgt tcggccaagt ctacgatgat ccggttgtcg gcatcccagc ccaagcgggt
     5941 ttttacggtg acagggatgt tcaccgcttt gacgacttca cgggtgatgt ccagcatcag
     6001 tggaatattg cgcagcatgc cggcgcctgc tcctttgcct gccactcgtt tgacagggca
     6061 accgaaattg atatcgagaa tgtccggatg agcggcttcg caaatttgcg cggcttcgac
     6121 cattgtcgga acatcacggc catatatttg tatggcgacc ggacgttctt catccgccac
     6181 attcagcttt tgctgtgttt tatttacact gcggatcagg gcgtctgctg aaacgaattc
     6241 ggtataaacc atatcggcac caaaacgttt gcacatcaac cggaaagaaa tatctgtaac
     6301 gtcttccatc ggagctaaga agacggggcg ttcgcctaaa tctattgtac ctattttcat
     6361 atttatatta tcaatgacgg ggacaaaggt actgatttcc tgctaaaaac agggataaaa
     6421 ggatatctac taaaaagtgt agtaattgat caatagaaag tacaaatgtc atactgtcaa
     6481 tgatatagat aaaatgataa gctgaaatca tgatagttgc atgatagtag tatgatagtt
     6541 aaaaatagaa actatcatgt cttaaggtat tgaataacag attctaaagg acaacaatga
     6601 cagtatgatg gttgttttgc aaatctttat agaaaatggt atttgatcac gattttgatg
     6661 ctctgagaaa cggataccca tgcaattctt ctcggatatt attcctacct ttgcgaacga
     6721 accagtaaat gtataagaac ttgaacgaga aagattttga aataatggcg cctgtcggtt
     6781 cgtacgaatc actgatggcg gctatccaag ggggagccga ttctatctat ttcggtatcg
     6841 aaggattgaa tatgcgttcg cgctcttcca ataactttac gacagacgat ttgcgcaaga
     6901 tcgttgcgct ttgtcgtgag cacggtatta agagctattt gaccgtcaat acggttattt
     6961 atggggaaga cctgcctctg atgcgcgaga ttatcgatgc ggcgaaggag gcggaagttt
     7021 cagcgatcat tgcggccgat gtggcagcta tgaactatgc caacagcatc ggacaggagg
     7081 tgcatctttc cacacagctc aacatttcca atgcggaagc actgaaattc tatgcccgtt
     7141 ttgccgatgt tgtcgtcttg gcgcgtgagc tgaatttgaa acaggtgcat gaaatctatc
     7201 ggcagatcgt cgaccagcag attacgggac cgaaaggaga actgatccgt atcgaaatgt
     7261 ttgcccacgg agctctctgt atggccgttt ccggtaaatg ttacctgagc ctgcacgaaa
     7321 tgaacgcttc cgccaaccgg ggagcttgca tgcagatttg tcggcgtgct tattcggtaa
     7381 aagataaaga cagcaatatc gaactggata tcgaaaacca gtatattatg tcgcctaaag
     7441 accttaagac aattcatttc atgaataaga tgatggatgc aggtgtacgg gtattcaaga
     7501 tcgaaggacg tgcccgcggt cccgaatatg tccgcctggt gaccgaatgc tataaggaag
     7561 ctgtgcgtgc ttattgcaat ggcacgttcg atgaaaagaa agttgccgct tgggacgaac
     7621 gcctgcgcag tgtgttcaac cgaggattct gggacggcta ttatttgggg caacggttgg
     7681 gtgagtggag tagcaaatat ggctccggcg cgactaagaa gaaagtgtat gttgccaaag
     7741 gaatcaaata tttcgacaag atcggcgtgg cggagttcga aatggaatcc ggtaacctga
     7801 aagtgggtga tgagatcctg attaccggac cgacaacggg tgcggttatg cagacgatag
     7861 aagaaatccg tgtggacttg aagccggtgg acgagaccgt taaaggtgaa cggttctctc
     7921 tcaaggtgaa cgagaagatt cggccgtctg accgattgta taaaatggaa aaggttcaac
     7981 ttgaaaaggt atttgaataa tgaaagagta tatttttaaa ctgacagaca aggtccgtga
     8041 ctacgaatgc gacctgcaag gagtggtcaa caactccaat tatcagcatt atatggaaca
     8101 tactcggcat gaattcttgg agtcgcttgg cgagaacttc ggaaagatgc acgaaaaagg
     8161 ggttgacgga tttgtatcgc gggtagaaat ccagtataag acctcgctca agagcggcga
     8221 cagctatatc tcttgcctca atgtctataa aaaaggagtc aagctcgtat tcgagcagga
     8281 tatatatagg gcttctgaca atgcattggc gacgaaagga atcgtcgagt cggttatcgt
     8341 tgagaacgga aagttgacac gcggtgaata tttcgacgaa atgctaaaaa gaatagaaca
     8401 tacatgactg acaaacggat ttaccaaatc ggccttacta tgataaacgg cgtgggagat
     8461 atcctggcgc gtcatctcct gcaggctttg ggagaagcag aggctgtgtt tactgaaaag
     8521 caacagttgt taggaaggat ccctggtatc ggcagcaata ttgctgccga aatcaaacgc
     8581 ccggaaatct tgcaacgggc ggaaaaagag ttggctttta tcgagaaaaa caatatttcc
     8641 tgttattatc tgactgatac agattatccg gtgcgcttga gagaatgtcc ggatgcccct
     8701 atacttttct attttaaggg aaatactaac cttgatgcga cccgtatcat cagtattgtg
     8761 ggtactcgca acgcgaccga atatggtcgg gagcttaccg aatcccttat aaaagacttg
     8821 gcaaaagtga tcccggactt gttggtcgtg agtggattgg cttacggcat cgatatctgt
     8881 gcccaccgga acgctttgta caaccgactt ccgactgttg ctgtgctggc gcatggcttg
     8941 gatcgtatct atccttcctg ccatcggaat acggctgtcg aaatgctgga atcgggcggt
     9001 ctgttgaccg attttcccag cggtacagaa ccagaccgtc caaatttcct ccggaggaac
     9061 cggattgtcg ccggaatctc ggattgtacg atcgtggttg aatcggcaga aaaaggaggc
     9121 tctttggtaa ctgccgatat tgcattctct tatggccggg atgtctatag ctttccaggg
     9181 cgcatcggtg acagccattc caaaggatgc aacaatttga tccgacaaaa taaagccggc
     9241 ctgatcactt ctgcggacga tctgctctcc gctctttgtt gggatatcca agctggggct
     9301 acttccgttc aaacggagtt gtttttcgcc gaggcggaaa cattcacctc ggaacaaaat
     9361 ccggttttag ccattatgcg aacgcggaat gagatccata tcaacgagct tgcctcagtg
     9421 ttggagatac cggtacatca actctctatg ctattgttcg aactggaaat aaacgggaag
     9481 gtaaaagcgt tgccgggaaa tctctataag ctgtcctgac cggctttttc gtatacgatt
     9541 tgtatgtggg agaagaaacg gaacctctat aaacaattaa aggctgtctc acgacaaccc
     9601 ctaaccaact ttgttaacct taaatctaat actattatga aaaaaccaca ttgcaaagat
     9661 acactcgtca agagcgtttg tcaagcattt tgtcgctaat acttgttaat cagatgagca
     9721 taaatagcaa aaagatttta atcggctata aagagtcctt taaactgcgt tattttgtta
     9781 aatcgagtcc ttgaaacagg tacggatagt ccgtttcgat cacgtcggga cgagtgctga
     9841 tctctgaccg gtaaccggcg gttttctctg tttccgtttt cgcgcgatca tgtgtcggag
     9901 caacggaaat catgcacatg actccgttac ggtgcagagc gtcatacagt ggttgctgtt
     9961 caggcttcat cttcgggcct acataagcca ttacctgttt ccaggggatg ccggcttttt
    10021 cataattatc gaattcttcc cgattcttac accagcaaga aaacatcgca tccggtttcc
    10081 ggtcgagata atagcgggct tgactggcgt tatgtaccgt gtacatgacg ttaacaggct
    10141 tttctgtttc tataaaatca gccataactt ctaaaggtac atccttgata tccaaattca
    10201 ggattgtttt gcctttgctc cattccaggc attcttttaa agttggaatt ttgaaggctg
    10261 tcacgttgcc gtttcggtcc accagattga attgttgcag ttctgcataa gtgtaatctg
    10321 aaacctttcc tttcccggta gttgtccggt cgatggtttc gtcgtgcatc aatacgatta
    10381 tcccgtcttt tgtcaaacgc ggatctatct cgaaaaacga ttccatatag gacaaggtct
    10441 tttcgaatga ttcgatgcag ttctccggat agccgtctag cattccacca cgatgtccac
    10501 tgattacaat cgggcgatcg ggagcatacc ggaaataggc ttgtagatcc cggctgttct
    10561 tcacagtaat gtaatgagga ttttgttctt tgtctgaagc caaaagattc ccggcaggca
    10621 taaaaccccc taaaaggagt accaaaataa aagatagcat tttcatgata ttgtatttat
    10681 atagattctt tgtcaattat gcggcttaaa agtaagactt ttttatcagt ggcgtactat
    10741 aaaagcacta taaaaacatg aaaatatgac aggcaacaag atgtgcaaag aaagaggcag
    10801 gtatataaaa aattaaggat tgtcatctcg acaaccccta accaactttg ttaaccttaa
    10861 atctaatact attatgaaaa aaccacaatg caaaaataca ctagctaagc ttgtttgtca
    10921 aaccttttac ggataatata tgttaagctc taatagctat tttgtcaaaa aatgttggtt
    10981 atttataaac tatacagatt ccatgtaaaa actgctaatt caaatacttt ttatcgtcgg
    11041 aaaaagtgaa atcccatgct taaaaagtgt ccccttggag tatataaaat cattaattaa
    11101 tataggggat gctttggtgt ggctgcttat agataaattc ctttttggcg catgcagcga
    11161 atagatgata gattattaat tgttaataca aattaacgca ttatttcttg cacatttacg
    11221 atgtattcgt agatttgcga tacgatcgta aaaaataata tagaaacatg gaaagattaa
    11281 caagacagga agaggatgta atgcgctgga tctggcagat cgagccgtgt tttatcaaag
    11341 acatcctggc gaagtatgaa gagcctaagc ctccttatac gacactcgct tctattgtga
    11401 agaatctgga acgtaagaaa tacgtgaaag cgaaacgtta cggaaatact tacgaataca
    11461 ggccgctgat cccacaggag gaatataaac ggacgtttat gggaagtgtg gtgaacaact
    11521 atttcgagaa ctcttacaag gaaatggtct ccttttttgc taaagaacag aagatatcga
    11581 ccgatgagtt gaaagagatt atcgatatga ttgaaaaagg acgagaataa actgttaaat
    11641 acataatgcc atgacaccgg aatttgccta cttcttgaag gtaaatgtag cttttatact
    11701 cctttatgcc ttctaccggc tgttctttta taaggacacc ttctttaaac tacgccgtac
    11761 catcttgttg gcatttttcg gggtgtcatt gctttatccg ctgatgaata ttcaggattg
    11821 gatccgggag caggggccga tagtggaagt catacaaatg tattcagcca ttttgcccga
    11881 aacgacaata acccccggca atgttcccca aacaaattgg catgatttgt tacttcccgg
    11941 tatttcttat ctttattgga gcggtgtaat tgccttatcg ttccgttttt tagtgcagtt
    12001 gagcagcatc ttgttactgg cacggcggtc ggaagtgact ttgatccgta acgtacgtgt
    12061 acatctgttg aataaaccgg ccggtccttt ttcttttttc cggctggtat ttctgcatcc
    12121 cgacagccat tccgagaaag agatcgatga gattttggta cacgagtgta cgcatgtcag
    12181 ccagtggcat tcgattgacg tgattatttg cgaattggtt tgtatcatct gttgggtgaa
    12241 tccgtttgtc tggctgttga aaagagaggt acgtcataat ctggaatatt tggcggatga
    12301 tacggtactt gaatcgggct atgacagtcg tagctaccaa tatcaccttt tggggttggc
    12361 acataccaat agatcggtga cctctttatc taataacttt aatatgctgc atctgaaaaa
    12421 tcggatcagc atgatgaata agaaacgttc ccggagcata ggtaggacga aatacttgat
    12481 ttttataccg gttgtgggcg ccttgctgat tttaagcaat gtcgatgcat tggcccggat
    12541 cacggacgaa ctgacggaaa gcacgtttgc cgatgtcttg ctaccggagg ctatcttgcc
    12601 gttccctttt gtcggtgatg cttctcctgc tgaaaaacgt gaggagtatg tgctatcgga
    12661 ggaaggtatt gaggctgcca gacgtgcccg taacccggtg tttaccgttg tggaggtaat
    12721 gccggaattc cctggcggac agggtgctct gctgaaattc ctggcgacga atgtcagata
    12781 cccggaatcg gccgttaaaa tatggtatag agggacgggt tagctgttct ttcgttgttg
    12841 gaaaagacgg ggctatctcg gaggcagaag tgattcgtgg ggtaagtccg gaactgaatg
    12901 aggaggcttt gcgtgtgata aactccatgc cggtatggtc gccggggaaa cagcggggca
    12961 aagtggttaa tgtcaaatat acggtaccgg taactttccg gctttccggt ggaaagaaaa
    13021 aaacatcctc tcgtatcgtg cagaggcaga ttaaagaagt cgatacgtcc ggtcgtgtct
    13081 ttacggtagt gcaacagatg ccggaatttc cgagtggaca ggcttcgttg ttgaaatatc
    13141 tggcaacacg cataaaatat ccggctattg ctcaggagaa tggaatacaa ggacgtgtct
    13201 cttgctcttt cgttgtcgac acggatggaa gtttgaaaaa tattgaagtg atccgtggaa
    13261 tcgatccttc gctggacagg gaggctgtcc gggtgatccg ggaaatgccg aaatggaatc
    13321 ctggcgtaca aaacaatatg gctgtagccg taaaatatac ggttccggtt actttccgtt
    13381 tgcagtaatt gaccagaatc ggtcattaat acgataccat tatgaaatgt aagttttctc
    13441 tattactgtt tctttgcgta ctgtcccttt ggggacaggc gcagagtctt aatcttcagg
    13501 aattggtcaa taaaaaacaa tttcaggaag ttgtagcacg tgcggatagt cttactcctg
    13561 ccgattcagc cgattatgct acaatgtcgg caatcgggca ggcgtatgag ggactgttgc
    13621 gctataagga ggcctatcag tgtttttctc attgcttgaa gatggatacg aacaatgtgg
    13681 atgcattgaa cgccgttgcc aggaatgcga tcaatttcgg aaggatagcg gaagctaaac
    13741 aatgttatcg taaagtattg ggaaccgaca gcatgaactt ctatgccaac tatcagttgg
    13801 cgcgtctcta ttatcagttg ggagattatg gtcgagcgac ggaacactat catatacttg
    13861 cttccatcga aggtgaaaat ccttctatcc tgaccgggct ggctgattgc catattaaaa
    13921 gagggaccgg tcctaatacg atgatcgctc tttctttgta tgcccgtgct ttggagctga
    13981 acccggaaaa tgtacgtgtg gcatcttctc tgataaatac gttattgcgg atgggggacg
    14041 gacagggagc tttgcaggtg tgcgataccg ccttgttcta taatccggat aacagccaga
    14101 tacggcagag taaagggatg gctctctata tgacgaaaga ttataagcag gccgattcag
    14161 tctataccgg tctattggcc gatggcgatt cttctttttt gaatcttaaa tatgcggggg
    14221 cggcccgcta tatgtccggt catgcacttg atggggtcga gctgctggag aaggcctatg
    14281 aaatagattc gacggatgtg gaaacagtca tgttgtatgg cgcttccctg ggaaaaacat
    14341 acgaccgtaa acgggcttat gagcttttcg atctggcgga aacgaatatg cagccgaaaa
    14401 aattcctagt taatatgttg acgaccttcc gaggtgatgc cttggaaagg gacggccgtt
    14461 ggcccgaagc ggaaaagctg tattatgccg catggaagga agacccaacc cagttgcact
    14521 tcctgtataa gatcagtaca caatactggg atgtcgatcc gggactcttt cagcaggagg
    14581 aaaaattgca aaagacgatt ttcagtagat acacttacct gacagcctat atgaagacag
    14641 acaagtcgca aaagtatctt tataattacc gccctttctt ggaagcggtt tgtgaagatg
    14701 cctttttccg gaatgccgat gaagtgacga tgttggctcc cgatgggaag aagacgaagt
    14761 tggctgtcgc tgatctgcgt gccttggtcg cccaactgcc gcagatgccg gaagatgaac
    14821 gtttgaggcg cgagaagatg caggaacata ttaaaaaagc cagggaaaaa gaaaaggaat
    14881 tgcgtaaaag cggtgctaaa ctcgatacgc tcgccctgag taaggaagaa aaagagaaag
    14941 cacggaaaat gttgaaagac gccgacttgg aatagataga atatctgaac aatataatcg
    15001 atataaa
//
