LOCUS       gnlProkkaLKFECMPP_8    16944 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LKFECMPP_8.
ACCESSION   gnlProkkaLKFECMPP_8
VERSION     gnlProkkaLKFECMPP_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:13:27
            Original ID  :: gnl|Prokka|LKFECMPP_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 67384
            Orig. end    :: 84328
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16944
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12425]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12425
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..16944
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16944
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             2580..3788
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.5; E-value: 8.1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_65"
                     /sec_met_domain="Metallophos_2 (E-value: 5.6e-10, bitscore:
                     31.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVII
                     SGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFFQHQGLH
                     LSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYILEDMEKA
                     FDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFDYVALGH
                     IHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLEVKRPIV
                     ALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTDIVEITF
                     SRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESVFEEIER
                     SRQ"
     CDS             3785..6964
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 498; E-value: 9.8e-151)"
                     /gene_kind="other"
                     /locus_tag="ctg8_66"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AITVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDHFQKSLEERLRQSNKDMEKRQAQLDGHFASQVWSV
                     EELALLEQTPASEKLTRLEEFLSQRQENVTKQKSILKAAHEDLAQLQKSFQTAQDLAKI
                     FQELEQAKERYRMEIEEGAQGQAEAKAHLEELQFAQGLQETISSLKQYQKQLVQLEQDL
                     DIAQEVLSEKRQAFEDVKAQKEELAVQSKDFLQKEEELETWKEDIIYAQSLAQEQEKIK
                     RSMTNYKQLEETYQQARKEIEMLNKSLSDLEANRLSLESLHEAEKLLQIVGYSVENQLA
                     QDLKEIEDLNQELTKTEKRHQMLSFDIDQAQEILKELEEELRRTLASRRQLMIVQLQAE
                     LEEGQPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVAKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIHKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEKGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             7363..7875
                     /locus_tag="ctg8_67"
                     /transl_table=11
                     /translation="MAAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQ
                     PYMTESAYSQELTSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSD
                     LKNANQSKTNQTETRTVNLNYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPS
                     LPNTTTK"
     CDS             7885..8016
                     /locus_tag="ctg8_68"
                     /transl_table=11
                     /translation="MNIEECKQISILDVANRLGISFKQVYDKAVYWIYSGVKGQYEY"
     CDS             8028..8186
                     /locus_tag="ctg8_69"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             8365..8931
                     /locus_tag="ctg8_70"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             8949..9761
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.8; E-value: 2.9e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg8_71"
                     /transl_table=11
                     /translation="MLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIFTEHKGNYG
                     YRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAENLIQRQFE
                     ASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQVKAMLEQAF
                     TEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESFFGILKSEM
                     FYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_72"
                     /sec_met_domain="TIGR01716 (E-value: 6.4e-51, bitscore:
                     165.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             10944..11036
                     /locus_tag="ctg8_73"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             11106..12425
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_74"
                     /sec_met_domain="Streptide_RRE (E-value: 1.3e-24, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.3e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.2e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.8e-13, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             12422..13513
                     /locus_tag="ctg8_75"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             13607..13822
                     /locus_tag="ctg8_76"
                     /transl_table=11
                     /translation="MLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERISKGE
                     FKVKFKIVPPNESDVFFDTLFSACIL"
     CDS             13773..14210
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_77"
                     /sec_met_domain="TIGR04085 (E-value: 6.2e-16, bitscore:
                     51.0, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-13, bitscore: 42.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVMFFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAG
                     VRACSINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKC
                     SECPLPWCGGGCRCSALELDGTLLGSDLACFYEQKGGGVVV"
     CDS             14207..14296
                     /locus_tag="ctg8_78"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             14526..15437
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_79"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             complement(16435..16536)
                     /locus_tag="ctg8_80"
                     /transl_table=11
                     /translation="MEEVRKLRQEKAELEKENDFLKKAAAFFAKEID"
ORIGIN
        1 tggtcttgtg gtaatgaatc atatgctggt aaagatattg ctgatatggc tgattacttc
       61 cgtagtgttg acaatactcg tccagttcac tatgaaggtg ttgcatggtg tcgtgagttt
      121 gattacatta cagacatcga aagtcgtatg tatgcgaaac cagctgatat cgaagaatac
      181 ctcacaactg gtaaactagt tgatctttca agcgttagtg ataaacactt tgcttcaggt
      241 aacctaacta acaaacctca aaaaccttat atttcatgtg aatacatgca cacaatgggt
      301 aactctggtg gtggattgga actctacact gacttagaga aatatccaga ataccaaggt
      361 ggatttattt gggatttcat tgaccaagct atttacaaaa cacttccaaa tggtagtgaa
      421 ttcctatcat atggtggtga ctggcatgat agaccttctg actacgaatt ttgtggaaat
      481 ggtatcgtct ttgcagatcg taccctaact ccaaaacttc aaacagttaa acatctttac
      541 tctaatatta agattgctgt tgatgaaaaa tcagtaacta tcaagaatga taatctcttc
      601 gaagatcttt ctgcttatac tttcctagct agagtttacg aagatggtag aaaagttagt
      661 gaaagtgaat atcactttga tgttaaacca ggcgaagaag caacattccc agttaacttt
      721 gtagtcgagg cttcaaattc tgaacaaatt tacgaagttg cttgtgttct gagggaagca
      781 actaaatggg ctcctaaagg tcatgaaatt gttcgtggtc aatatgttgt tgaaaagatt
      841 agcactgaaa caccagttaa agcacctttg aatgttgttg aaggggactt caacatcggt
      901 attcaaggac aaaacttctc aatcttgctt tcacgtgcac aaaatacttt agtatctgct
      961 aagtataatg gtgttgaatt cattgagaaa ggtcctaaac ttagcttcac tcgtgcttac
     1021 actgacaacg atcgtggtgc tggatatcca ttcgaaatgg caggctggaa ggttgctgga
     1081 aactatagta aagttacaga tactcaaatt caaatcgaag acgactctgt taaagtgact
     1141 tatgttcatg aattgccagg cttgtctgat gtcgaagtta aggtaactta tcaagttgac
     1201 tacaagggtc gaatctttgt tactgcaaac tatgatggta aagcaggttt gccaaacttc
     1261 cctgaatttg gtctagaatt tgctatcggt tcacaattta caaaccttag ctattatgga
     1321 tacggtgcag aagaaagcta ccgtgataaa cttcctggtg cctatcttgg tcgatatgaa
     1381 acatctgttg aaaagacatt tgctccatat ctaatgccac aagaatctgg taatcactat
     1441 ggtactcgtg aattcacagt atctgatgat aaccataatg gtcttaaatt caccgcactt
     1501 aataaagcat tcgaattcag tgctttgcgt aacagtactg aacaaattga aaatgctcgt
     1561 caccaatatg agttgcaaga atctgatgct acatggatta aagttcttgc tgctcaaatg
     1621 ggtgtaggtg gtgacgacac atggggtgct ccagttcatg acgaattctt gcttagctca
     1681 gcagatagct atcaattaag cttcatgatt gaaccactaa attaggtagt tattaagaat
     1741 ctagttgtac attatttgat aattataaaa gagaagcttt ggaggcttct cttttcatgt
     1801 tttaaaggag attaaatcat tagtgtgtta gtatcttcca aaaatctaca agcggtactg
     1861 attagcactc caacacatta taaatatatt tcaagtgatt taagatagga attagctatt
     1921 accggtgttt ctctaaaaga aataaaaatc ataccattcg ttcagatgga ataatgcatg
     1981 tgacttataa aaaatatcaa gtagggaaat agtaaatact acatgcctag ttccaagtca
     2041 gctaacaagc tacggataaa aaaagcctag aataaagtaa aaagtcagga gcccttaggg
     2101 ttcggattat ttttaggttt tcatggtgaa aaatttaaaa aggatcggta ctgacaataa
     2161 cgaaaagtga gtaaatatta ttgcctaaaa tacaagatgt gcactagtac caacctatat
     2221 gataatgctt agaatctata aaagtcaatt aaaagaatag ataatattga ttttcttggt
     2281 tagaggtatt taaattactt aaccaattga ggcagggtaa tctagactat attgattact
     2341 acaacaacaa atgcattaag gtaaaactaa aaggactcaa tcctgtgcaa tacagagcta
     2401 aatcctttgc ttacataaat tgtctaactt tttggggtca gtacaggata gcttgggaga
     2461 gattttttga tctttacagc taaaaaacgg gaaaactatc aaagcctgtg aaacttttaa
     2521 gcagtattta gcttgataag gtacaataga agtaagacaa aatgaatgag gaggttgtca
     2581 tgaagttttt acatacgtca gattggcatg taggacgaac cctcaatggc tggtctttgt
     2641 tggaggagca ggagtgggct tttcaacaaa ttgtggattt ggctattagc gaaaaagtgg
     2701 atggggttat catttctggg gacctctatg accgtgcggt gccccctgtg gatgcgatta
     2761 agctttttaa taagaccttg gcccgcttgg tactggagga gcagattcct gtctatgcga
     2821 ttagtggtaa tcacgatggg gctgaacgtt tacattttgg gcgtgacttc tttcaacatc
     2881 agggccttca tttaagtaca cgtttggagg aggcttttga gcccattgag ttggagaatt
     2941 gccagatttt tctgctgcct tttatcgatc ctattgatgc tcgtatttac tataaggatg
     3001 atgagggaaa ggaaattcag gggattggtg atgccttgac ctacattctt gaggatatgg
     3061 aaaaagcttt tgatcctgac aaagctcatg tcttggtgac gcattttgcg gtttctaaga
     3121 aggatgatag cgatggtcag ggtcttcgag aattgatgtt gtctgaaacc agtaatacgg
     3181 taggtggtct taccaatgtg accagtgacc ttttcaagtc tttcgattat gttgccttag
     3241 ggcatatcca tacgcgtttt gctagtccta ccaagcgcgt gcaatattca ggcagtccag
     3301 tcgcctttaa tgtcaaagaa gccaagcgta aggaagaaaa gggtgtctat attcttgaat
     3361 tggatgcgtc tggtgatatg tctcagacct tccatactct agaggttaaa cggccgattg
     3421 tggctttaca ggaatctttt gaaaccttga tgtcacctga attttataag aatcaacctt
     3481 gtcaaaaagc ctggttcgcc tttgatattc aactgtctag tcgtaaggaa ttagagggta
     3541 tcaatgtgcg tgcccgactg gaagagattt atgggacaga cattgtagaa attactttca
     3601 gtcgtctggg tgatgttagg gaagaaaact tgaccgttga tcagcactta aaagatttgg
     3661 aaatgcagtc gccccaggaa atcgtatttg atttttacca gacagtaact gggggcgatg
     3721 tcttatctga gagacagact gcccttgtgg aaagtgtttt tgaggagatt gagaggagtc
     3781 gacaatgaga ccagtccagt tagaattgac caattttgga ccatatcgta aggaagttat
     3841 taatttcact cagtttgacc atgctcccct ctttttgatt ggaggggaca caggggctgg
     3901 taagagtact ctctttgatg ccataacggt agccttgttt gctacgacca gtggtgatcg
     3961 taatgttgag gagatgcggt caactttcgc tggtccagag gatgatttga ccaaggtgac
     4021 tttctatttc caacaaggca atcaccttta tcgcattgac cgagttctcc agcaagagag
     4081 ggccaagcag ggtgggggca ctaccatgca aaaggcgacg gcttctctag tcattgtgga
     4141 taagattggt ggtcaggaaa ttgaaaagct tggggataag atcaaggaag tgagtgacca
     4201 gattgagcag attttggggc tcaatgctga gcagttcaaa cagattattc tccttccaca
     4261 aaatgatttc agccgtttct tgaaagaaga ttctaagacc aagactcaaa ttttaaagaa
     4321 aatctttgga acgggtattt ttgaccattt tcaaaagagc ttggaagagc gtcttcgtca
     4381 gagtaataag gatatggaaa agcgtcaggc tcagctagat ggccattttg ccagtcaggt
     4441 ttggtctgtg gaagaattag ccctcttgga gcaaacgcca gcctctgaaa aattgacacg
     4501 tcttgaagag tttttatctc agcgtcaaga aaatgttacg aagcaaaaaa gcatcttgaa
     4561 ggctgcccac gaggatttgg cacaactgca gaagagcttc caaactgccc aagatttggc
     4621 aaagattttt caagaattgg agcaagccaa ggagcgttac cgtatggaaa ttgaggaggg
     4681 agctcaggga caggcagagg caaaagcaca tctggaggaa ttacagttcg ctcaaggatt
     4741 acaagaaacc attagtagct tgaagcaata tcagaaacag ttggtacaat tagagcagga
     4801 ccttgacatt gctcaagaag tattaagtga aaagcgtcag gcgtttgagg atgttaaggc
     4861 tcaaaaagag gaactcgcag ttcaatctaa ggattttctt caaaaagaag aggagcttga
     4921 aacttggaaa gaggatatta tctatgccca gagtcttgcc caagaacagg agaaaatcaa
     4981 acgttcaatg actaactaca agcagttgga agaaacctat cagcaggcta gaaaagagat
     5041 tgagatgctt aacaagtcct tgtctgactt ggaggctaat cgtcttagtt tagagagttt
     5101 acatgaggcc gaaaaactcc tccagattgt gggctacagt gtggagaatc aactggctca
     5161 ggacctgaaa gaaatagagg acttgaatca ggagttgaca aagaccgaaa aacgtcatca
     5221 aatgttatct ttcgatattg atcaagctca agaaattctc aaagaattgg aagaggagtt
     5281 aagaaggact ttggcttcac gccgtcaact catgatcgtc caactgcagg cagagttaga
     5341 ggaggggcag ccttgtatgg tttgtggtgc tctggaacac cctaatgttg gtggagcaca
     5401 ggctgatgaa gtggccttga aaaatctcat ggatcaggtg gagaagcttc aagctcaaaa
     5461 agaaaagcaa gtcgctactt tatcaaatcg tcaggctacc ttgagtgaag ttgcatctaa
     5521 acgtcaggat ttgcttgacc aagtggctaa agtcaaggca actcttgaaa agcactatca
     5581 agaattagaa gagcacgtta agggacggtt tgattttgat ttttcgatag actatgaaac
     5641 tgaccgtggg caagccctac tcctgaaggt tgagcagtat tatcaagagt tacaaaaacg
     5701 ttatgataag gaagagacag attatatccg atatcaagat gagctaggta aggctcaaaa
     5761 aaaagcgaca gatttggcta aaacctatca agaggccaag gcagtgcttg accaagctca
     5821 agaacgctta gaggacctgc aggaagctca tccagaactt gagtctgttg aggtatatca
     5881 agaacggatt tcccttgctc atcaggagct gaacctctac aataagcaag tcaaggaaaa
     5941 tagcgaagcc tacaaccaac ttcatgccga cattaaagga ataaaggggc agattgagag
     6001 tataactaag tctaaagata aggtaaatca agatgttaag cgattatctg ctgaattaga
     6061 gcaaagtctc aaggctgaag gagccctcgc taatgactta gagcaggtcg aactctggct
     6121 tattgaggta aataatcaag ctattcctat gcttcaggcc aaattaacga cctatgcaac
     6181 gctcaaacaa gaattacagg cgcagattca taaggggcaa gagcttctcc aaaatcaaga
     6241 acaaccagat ctcgatagtc tagcgcaagc agtacagaat tgtcaggaaa tctatgatag
     6301 gcagctcgct cagttttctg tcatggaaaa gggacttaag gatgcgacgg ctacctacca
     6361 agcggctaaa acccttcaag acagtaacca agaggccttt aaggcccacc aagaactcag
     6421 tgatttggtt aaggtggtta agggagaaaa tactgctcta actggtcgtc ttaatcttga
     6481 ggtctacgtt atccgtcagt atttccaaca aatcttggac tatgccaatg ctaactacat
     6541 cggactatta acggataacc gctattcctt tgttctaagt gagaaaggac gcagggcgcg
     6601 tgatcacttc ggtttggata tcaacgtcta tgaccagctg acaggtagtg aacgctccgt
     6661 taaatccttg tctggtggtg aaacctttat cgctgcactg gccattgccc tatccctctc
     6721 agaagttgtc caaaatacca gcaagggtgc cgttgttgaa gctctcttca tcgatgaagg
     6781 gtttggctca ctggataagg aagccctgac caaggccatt tctgttctgg aacaaatcgg
     6841 tgaaaaccgc atggtcggtg tcatcagcca cgtagacgat atgaaagaag gtattgctca
     6901 gcaactagtt atcatcaagt cgcacgatgg cagtagccgt attaaaattg tggataaggg
     6961 gtaggaggaa tcagtttata taatactcta tatcagataa tcgcagttgt agccatgtca
     7021 aatttgttct aatcagcata gaaaaaaggt agttgcatca acaactacct tatgtagaat
     7081 tgttaaaaag ctgatggttt gtataacata tttaattcgt cctactcgta aaaaagtgcg
     7141 gacggatttt ttgtcatcat atttgacaat gttatagcaa aaactaatca aagtaatatg
     7201 aggctaccta atgtctccct aattcgttga acttttagct aggtgaagta attatcaatt
     7261 tcctcctcat tttttagtat atccacctca tcaacaccac aacttactgc taattctatt
     7321 ggtcaacatt ctactgccaa acaaagtcga aaagaaatcg aattggctgc agctaaactt
     7381 gtagaggaca aacaagcaga agataaagca agtattttat catcagatac tgtaaaagaa
     7441 tttttgacac agtactatac gaaagaaaaa ctaggggaaa ataatacacg tattcaacct
     7501 tatatgactg aatcggccta ttctcaagaa ttgacaagtc aaaatgatgc catgaaccaa
     7561 gtgtataagg actatatttt ggattatcat tttgaaaaag cagatatctt tgtcaatcag
     7621 actacgaatc aagccattgc catggtctct tataatgtaa cttatgtatc tgatttaaag
     7681 aatgccaacc aatcaaagac aaaccaaaca gaaaccagaa cggttaattt gaactattcg
     7741 aaactacctg gtaagttatt ggtcaaccaa gtacaggttt ggaaatctgg gttagatgat
     7801 ctagataagg caactcctaa aactttagaa gaatcctcat ctgttccatc attgccgaat
     7861 actacgacaa aatgatgata ttttatgaat atagaggaat gtaagcaaat ttcaattctt
     7921 gatgtagcca atcgattagg tatctccttt aaacaagttt atgataaagc agtttactgg
     7981 atctatagtg gtgttaaagg acaatatgaa tattagaagg agaaaaaatg actaaacata
     8041 gttatgttgc gaaatttaag cgtaaagacg aaaccgtctt tacgaaaagg tttctagctt
     8101 cagatttatt tgaggctgtt gaacatgcgc tagagtatgc cactaagcga gatattctct
     8161 atctcgactt agggcatgca ggatagtagt cagtagaaag tagaggctgg gacaaaaagt
     8221 tctcagtcac aaaaaagcta gagatttcca attgtggaac tctagctttt taaattcgag
     8281 tcactctctt gttatatttc agaagatttt tggtcaattc tatttcacca agtctatcac
     8341 aatcatgcaa aaagcaacgg ttttatgaac tgcaccccaa aagttagaca gaaaaaatct
     8401 aactttcggg gtgtttttat tatgaaattg acttatgaag ataaggttca aatctatgaa
     8461 cttagaaacc aaggatatag cttagatcag ctttcaaata aatttgggat aaacatttct
     8521 aatcttagct acatgattaa attgattgat cgatacggaa tagaaatcgc taaaaaagga
     8581 aagaatcgtt actactctcc tgaattaaaa caagaaatga ttgataaagt cctatataaa
     8641 ggctattctc aagatagagt ttctcttgaa tatgctctcc caaatcgtgg gacgcttcct
     8701 aactggctcg cacactataa gaaaaacggg tatactattg ttgagaaaac aagaggaagg
     8761 ttatctaaaa tgggacgtaa gccaaagaaa aaactggaag aaatggaacg tcttcaagca
     8821 gaaaatgagt accttagagc ggagaatgca gttcttaaaa agttgagaga actccgattg
     8881 agggaagaaa aagagcaaga agaaaaacgg aaattgtccg aggattggta actgagtttt
     8941 ctttagatat gcttctaaag attattaagc ttgctcgttc aacctattat taccacttaa
     9001 aacagctgga tcaaaatgat aaggattatg acattaaagc tgaaattcaa gccattttta
     9061 ctgagcataa aggaaattac ggctatcgtc gaatgactct tgaattgaga aatcgaggaa
     9121 ttgtgattaa tcataagaga gttcaacgtc ttatgaaagt acttggttta accgctagaa
     9181 ttcgccgtaa acgtaagtat tcttcatatc aaggagaggt tggtatgaaa gcagagaatc
     9241 tcatccaacg ccagttcgaa gcatccaaac cattggaaaa atgctacaca gatgtaacag
     9301 aatttgccat tccagcaagc agccaaaaac tctatttgtc gccaatttta gatggcttca
     9361 atagtgaaat tatcgcctac aatctttcta agtcaccgaa cttgatacaa gtgaaagcta
     9421 tgttagaaca agcctttaca gagaaacatt acaaaaatac aattctccat agtgaccagg
     9481 gatggcaata tcaacatgat ttctatcatc attttttaga ggagaaagga atccaaccat
     9541 ccatgtcacg taaaggcaat agtccagaca acggcatgat ggaatccttc tttggcattc
     9601 ttaagtctga gatgttttat ggttatgaga agacgtttaa gtcaattgag catttggaac
     9661 aagcaattgc agactatatt aattattaca acaacaaacg cattaaggta aaactaaaag
     9721 gactcagtcc tgtacaatac agaactaaat cctttactta aattatttgt ctaacttttt
     9781 ggggtcagta cattatgccg ttgctttttg gagctaaagg acttttgtcc cagactcttt
     9841 atcccacgac gataacgata atgccttcaa atacgacaag aagaagtgtt agtaaaattt
     9901 gctttttcat gtgataatcc tcacttttgt ttttctttat tgtatgatat gatgaaagca
     9961 aatgaaaatt attcccatat atgcgtgatg gaggtgtagt atgaaaaaat ttggagaaat
    10021 ttttaaaaag tttcgagaat cgagaggatt acgattaaaa gacgtcgcaa aggctggtat
    10081 atcaacgtct cagctctctc gatttgagaa aggagaaaca gatttaacga tttcaaagtt
    10141 catgtttatt ttagatgaaa tcaatatgcc aatagatgaa tttatgtatg cggtccatga
    10201 ttttcataga gatgagttaa acgaactgtt atcgaaagta cgtcattttg tgtcaacacg
    10261 tgacgtagaa ggtatgaaaa aattacttta ttctcagatg gaactggaag ataggcgaga
    10321 aaaatttcat caaatcaata ttattttatt gaaaattcgt ctacaggatt tatcaggaga
    10381 aacttactat acaaaggatg atttgacata tttaacagat tatctcttta gtgtagaata
    10441 ctgggggtac tatgagttat tgattttctc gaatacttta gatgtattaa atcatgatgt
    10501 tttcatggtc ttagcaagag aaatgtttag gcgttctgat ttttacaaag aaattccaaa
    10561 taacagacga ttaatttcaa cgatgctttt aaatggatat attacatgtg ttgaaagaga
    10621 aaaatttatg gatgctttat attttgaaaa gcagctaaat caatgctttt ttattgagac
    10681 agaagtatat gaacgtttag tctttaagta tgcacaaaat ctttatcaat ataaagagga
    10741 tggaaatgtg aaagcaatta ttgaaatgaa gaagtgtgtt ggagcgatga aattagcagg
    10801 aagtcatcac ttagcaaaga cttatgaagg acatttagaa aaaattttag ctagtagtta
    10861 gaaaatgcaa atatgggaat attttattgt aagtgttgaa aagaaatata atcacagtat
    10921 catattcgaa aggagtacca aatatgtcta aagagcttga aaaagtcctt gagtctagtt
    10981 caatggcaaa aggtgacggc tggaaggtga tggcaaaagg tgacggctgg gagtgataaa
    11041 gtaatttatc ccataagtta agcagaggct atattttcct ctgctttttt agaaaggtat
    11101 tcaatatgat gacaatttca gaagattttt tatttagact agaaaagttt ggtggaattt
    11161 tgataaataa agtaactttt gaccgaattg agttagatga gagtgaagct tattttcttt
    11221 atttggttca aaatcatggt tttgaaattg ctacgtcctt ttttaagaaa gaaataaaag
    11281 cagggaaact agagcgagta ctcttattaa atatctattc tgataataat attgagggat
    11341 catcgaaaaa tcctgacgag actcttcaaa atgcgagaaa gcatgtagca aaattaaaaa
    11401 aacataacat attgagtttt ccgcttgaac tagtaatata ccccagtatg tactgtgatt
    11461 taaaatgtgg tttttgtttt ttagcaaatc gtgaagatag aaatgccaaa cctgctaaag
    11521 attgggaaag aattttgcgc caagcaaaag ataatggagt gttaagtgtt tcaattttag
    11581 gaggggaacc gactagatat tttgatattg ataatttgtt gatagcttgt gaagaactga
    11641 agataaagac tactataaca actaatgccc aattaataaa gaaaagtaca gtggaaattc
    11701 tagctaaatc taaatatatt acaccggttt tatctttgca gactttagat cctaaattaa
    11761 attttgaatt aatgggggtg agacctgata gacaaattaa attagcgaag tactttaaag
    11821 aggttggaaa aaaatgtaga attaatgcag tgtatacaaa gcaaagctat gagcagatta
    11881 tagaattggt tgatttttgt atagagaata aaatagatag attttcagta gctaattatt
    11941 ctgaggtaac aggatatacg aaaataaaga aaaaatacga tttagctgat ttgagaaggt
    12001 tgaatgagta tgttacagat tatataactc aacgggaagc taatttaaat tttgctactg
    12061 agggatgtca tcttttcacc gcttatccgg agttgataaa taattcaatt gaattttcag
    12121 agtttggcga aatgtattat ggatgtcgtg caaaatatac taagatggaa ataatgtcta
    12181 atggggatat cttgccttgc attgcttttt taggagttaa tcaaactaag cagaatgcct
    12241 ttgaaaaaga tttgttagat gtttggtatg atgatccgtt gtatggaggg attcgttctt
    12301 ttagaacgaa gaattctaag tgtttatctt gtggattgtt aaaaatttgc gagggtggct
    12361 gctatgttaa cttgattaag gagaagagtc caaaatattt tagagaccca gtttgtaact
    12421 tatgagtaag aagattttta atttatacgg aatgaatatg tttctatctg gattaccgta
    12481 ctactttgta ggaattttac tattaaagca cttaggtttt tcgttcacag aaatagctac
    12541 tttatcagtt attactgagc tatgtggctc agtttttgat attcctttaa gttatatttc
    12601 aagtaagatt ggttacaaga aaattttggc tatttcaaat ttattattaa ttttagcatt
    12661 atggggccta ttgtttggaa aatcaaatat aatatatatt tcagcgatat tttttggatt
    12721 gtcagaatca ttatcttcag gagttcttat ttcttataat tttgaaataa ttgatgacga
    12781 agttgtatat aaatcatttt tgaaaaatct caacacatta aaatatattt ttattgctat
    12841 tattacgatt atatctccac ctttattgca taggaattat atttatccta ttattatatc
    12901 cattgtattt gtaattttca gtttattata tttaatagga ttacccgaga ttaaaaagga
    12961 acaaaataat aaacaaaaat tttttagcct cgataatatt caaaatattc catggttatt
    13021 aataatatta ggagtagcat tctcaactct aattatgatt agcaattctt atgcagggat
    13081 attcttaaat gaacagggac tttcactaga tatgctggga attatactat ttatgtttaa
    13141 tatatctatg gctttgggga gttatctaaa aattaagttt gaagtaagct tgatgttacc
    13201 agtattagct atactcatgt tttttcaaac taatctaatc atccaaatta taatcctttt
    13261 attaatgcgt gttcttaatt ccaactacaa taatcatttt tattataaat ttaatatgtc
    13321 aatagaaaaa aatagagcag tatcatggtc agtatataat ttgtttattt cgattagttt
    13381 tatgttagct gatttcctag ctggtatttt tgctgataac tttagtatta ggagcaatta
    13441 tttaatattt ggtatagtag ctctttgttg cttagtatct tattcatttt ctaacagaga
    13501 gaaaagaact taaaagttgt atttctaatt catttgccaa attattgata gcacaattgt
    13561 ttgcaaattt agcagatatt ttctttagag tataagattg aatgatatgc ttggtattga
    13621 gtatatgtca gttatggtta tttgtcctac tggtagggct aatgacggta gtattttagc
    13681 agataaaaaa caatggtatc ctgtttttct tgatttaaca gagcggattt ctaaaggaga
    13741 gttcaaagtt aaatttaaaa ttgttcctcc taatgaaagt gatgtttttt ttgacacatt
    13801 attttccgct tgcattttat aatagatcag atttattaga aaatgtttgg catcaaaaag
    13861 tagatataaa ttttgataag ccaagggaaa tatcttgtca agctggagtt agagcatgtt
    13921 caattaatca taaaggagat gtatacgggt gtgacttgat gaatggtata gatgaattag
    13981 ttgctggaaa tgttaaagaa caaaagttta gcgaaatttg gcaccattct gctgtattta
    14041 ataaactaag atcaattaca tttgatgata tttctgggaa atgttcagaa tgtcccctac
    14101 catggtgtgg tgggggatgt cgatgcagtg ccttggaatt agatggaacg ttactgggct
    14161 ctgatttagc ctgcttttat gaacaaaaag gaggtggagt agtcgtatga aagaacattt
    14221 tgtgataaga ggtaagagag atttcattgt aaataaagta gcagatgaat acataggata
    14281 cgatctactt gattagagta ctattcattt gatgaaatag gagcagaaat actttattgc
    14341 atttctaaaa atttttcttt agacaagatt gtagaactat tacagcaaga ttatgaggta
    14401 tctgctaatg attgtaagca ggcaattatt tcatttttag aagaaactcc tattttgcat
    14461 attatttatg caaatttagt taaatctgat ctttacttac atttgaagcc ttttagagag
    14521 gaaaaatgat agattcaaaa gaaattaaca aatttgcctt tcccttagtt ttaacaaata
    14581 ttggtcaagt aattattggg cagatagcat tgcattttgc tgtgaacaat tcctcaattg
    14641 ctctgtcagg aatttccatt attcagaatc tcttatttgc ttttggtgga cttttaggag
    14701 cattcagttt gtcatttaat attaaaagct ctaaggcgta ctctaatcgg caaactaaca
    14761 ggtttgatga tttattgaaa tcaaatctaa ccttagattt aattatcgga gttgcctttg
    14821 cggtttttgt cattattttt ggaaatgtaa tcttgaagca gctctatgga tttaaagggc
    14881 aactattgtc cttatccacc atttatttag tcttcatgtc tccatatatc ggattgacat
    14941 tattaaactt ttcgctgaca aatttattaa gagttcaaaa gaaaacaaaa ccaattatgt
    15001 gggttggact tatcagttca ttaatagatg ttgtgttaaa ttatgtactg gtaccacaaa
    15061 tcggaattaa gggagcagcc atatcaacga ttgtatcctt agctttcata tcgcttagtt
    15121 acttgtttat ggtttatcca atgattttga aggctttatc cattacatct acaactaaat
    15181 ttgaattaat aacatttggt attcctttgg ttggtcaaga aattctggag agtgttttgt
    15241 ttattatggt gtttgatgcc ttgatgtcga gattaggagt agaattgttg gctatttatg
    15301 cagttattag tcaattgctt tcaattgtga gtgtaccttc ttttgtttat tcgacaaccg
    15361 tttctatcta tttacctgaa gcagagaaaa taggagaggt taacgtattt ttaaaaaaca
    15421 tatttaaaaa ttcataagat ccctgaaaag cgatattata gtcaggagaa aatgccttcc
    15481 ctaaaagttt atagtaattc ttaatctctc tgaagttgat gattatataa ttcaaattaa
    15541 ttatctaaaa aatagttata ttcttgtatc tctttgaaat aatctgctat cagtaatttc
    15601 tctttcattg tgagattatc tttagcgatt tcatatagga aagttcctat attatttcca
    15661 ataacggatc ctaaaatagg tattggaatt acagcatgtc ctaatattga ggataatgca
    15721 ctaactgata cttcaacaca taatatttgc gaatttagta aaaattcttc ttttgtgatt
    15781 aagtttttac ggaatttgta tgcttcttta gcgataccaa atgaagcagt gcacaatgaa
    15841 cttgctactg ctgcaggagt agctgtgtaa ttcgttaggg cgtatatcgt aatgcctcga
    15901 gtacttcctt ttatagctcc aattccacta tctttagaaa tttcaagaca atcgtctttt
    15961 gtaaactcac taatagtttt ccctaagcgc tttttttaat tattgctgtt ataaatgcag
    16021 tacccccctt ctagagaagc tgctatagcg gatatatagg ctccctgttt taaagtaggt
    16081 ttgcttttat cgtacatatc tcttataatg ctagtatcaa tatcctttat attacctttt
    16141 tcattataaa tagtggtatt gatttgattc ctttgtacct ccctataact aactttcgaa
    16201 ggctctatat cagaaagttt gatgctttct gtttcgaaga attgatttac ttctttccat
    16261 tgcactcatg gtagatatct cgaatagtat taagaatagc tttcttttga cgatgatagt
    16321 tagtccttgt ctttttaaga taattataat aagcattggg atgaatattc atatgcaaga
    16381 acaaccaacg caaaccaaaa tcttctttat agttatcaat aaaacgatat gcctctaatc
    16441 gatttccttt gcaaagaatg ccgctgcttt ttttaagaaa tcattttcct tttcaagctc
    16501 tgccttttct tgacgtaatt tacgaacctc ctccatgagt tcaagctgtg atttttcttt
    16561 attattagtt tggcattctt tgcgataatg tcttacccaa ttagagattg aggcttggga
    16621 tacgccatat tcagcagcta agctttttaa tgttcatccg tcttgaatgt gcagtcgaac
    16681 aattttttat cgtgtttcgt ctggatagtg tttcatgtta tgtctcctat tctaatgaat
    16741 agtttaactt attaggtagg agtgttacaa atttactata ccagaacagt ctagtttact
    16801 atataagtct ctaaatcgtt ctaaatgttt aatatacaaa tctaattgtt ctggttttaa
    16861 ccatattttc gttggcataa ttttttctct tttcctaata aataaaaaag atagcacaaa
    16921 tatttccttg tgctatctca acat
//
