LOCUS       gnlProkkaMDENPFBE_21   10272 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDENPFBE_21.
ACCESSION   gnlProkkaMDENPFBE_21
VERSION     gnlProkkaMDENPFBE_21
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:53:40
            Original ID  :: gnl|Prokka|MDENPFBE_21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10272
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10272
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:10271]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..10271
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10272
                     /SMILES="NC(C(C)C)C(=O)N1C(CCC1)C(=O)NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10272
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             3..3653
                     /NRPS_PKS="Domain: AMP-binding (171-564). E-value:
                     4.6e-116. Score: 379.6. Matches aSDomain:
                     nrpspksdomains_ctg21_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (669-737). E-value: 5.8e-25. Score:
                     79.2. Matches aSDomain: nrpspksdomains_ctg21_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (747-1049). E-value:
                     2.5e-169. Score: 556.4. Matches aSDomain:
                     nrpspksdomains_ctg21_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1055-1209). E-value: 7.5e-53.
                     Score: 170.4. Matches aSDomain:
                     nrpspksdomains_ctg21_1_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     356.2; E-value: 3.9e-108)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_1"
                     /sec_met_domain="AMP-binding (E-value: 5.8e-124, bitscore:
                     400.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.4e-16, bitscore:
                     47.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.3e-80, bitscore:
                     256.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRPEGGKPFVQYLQEVRDTALEAYEHHDYPFEELVDKLELTRDM
                     SRNPLFDVMFVLQNMDQESLDLDELCLKPAANNGHQTSKFDLTLYAQEQPHGLLTFQME
                     FSTDLYKKKTIEKWLQYFINMLLSIIQDNKAVLGTINILNEDEAHYLIHELNRTKMDYP
                     RNETISRLFEMQAEQTPNAIAIVSDTQELTYADLNNWANQIASVLQRKGVGPDRVVALL
                     AGRTPELIAGMLGILKAGGAYLPIDSNLPVERIAYMLSDSRAALLLQSEKTEKRLLGIE
                     CEQIIIEDIQKQGEAKNVESSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRLVKNSNY
                     ITFTPADRLLMTSSIGFDVGSFEFFGPLLNGAALHLSDQQTFLDSQQLKRYIEHQGITT
                     MWLTSSLFNHLTEQLETTFSQLNHLIIGGEALSASHVNRIRNACPEVSIWNGYGPTENT
                     TFSTCFHIQKTYELSIPIGRPVGNSSAYILNQWGMLQPAGAVGELCVGGDGVARGYLHR
                     PDLTKEKFVKNPFVPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVRGYRVELGEIESA
                     LRHIDGVKEAAVLARTGQSGSKELFGYISVKAGTNAEQVRSLLARSLPNYMIPAYIIEM
                     ENLPLTSNGKLNRKALPEPDFASKQTYIPPRNELEEQLALIWQEVLGIQRIGIEDSFFE
                     LGGDSIKALQVSARLGRYGLSLQVSDLFRHPKIKDLSPLIRKSERIIEQGPIQGDVPWT
                     PVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALKKLAEHHDALRMVYRNDDRRW
                     IQINQGIHESQLYSLRISDLSQSESGWETKIKQEVADLQQSINLQEGPLLHAALFKTLT
                     GDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQLPPKTDSYQEYARRIQEYAQ
                     SSKLIREEAYWRSVEEQQAAELPYEIPHHVNIDFSKRDSLSFSLTEADTAVLLQNVNHA
                     YGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTVGWFTSMYPALI
                     SFENHRDELGTSVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEISFNYLGQ
                     FNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPARFHRNTME
                     QLINRIEHFLLDIMKHCAGQQKAEKTLSDFSSQSLTAEDLDSITSLVEEL"
     CDS_motif       54..173
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0001"
                     /evalue="9.40E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg21_1"
                     /protein_end="57"
                     /protein_start="17"
                     /score="69.5"
                     /tool="antismash"
                     /translation="RDTALEAYEHHDYPFEELVDKLELTRDMSRNPLFDVMFVL"
     aSDomain        516..1694
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_AMP-binding.1"
                     /evalue="4.60E-116"
                     /label="ctg21_1_AMP-binding.1"
                     /locus_tag="ctg21_1"
                     /protein_end="564"
                     /protein_start="171"
                     /score="379.6"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAIAIVSDTQELTYADLNNWANQIASVLQRKGVGPD
                     RVVALLAGRTPELIAGMLGILKAGGAYLPIDSNLPVERIAYMLSDSRAALLLQSEKTEK
                     RLLGIECEQIIIEDIQKQGEAKNVESSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPADRLLMTSSIGFDVGSFEFFGPLLNGAALHLSDQQTFLDSQQLKRYIE
                     HQGITTMWLTSSLFNHLTEQLETTFSQLNHLIIGGEALSASHVNRIRNACPEVSIWNGY
                     GPTENTTFSTCFHIQKTYELSIPIGRPVGNSSAYILNQWGMLQPAGAVGELCVGGDGVA
                     RGYLHRPDLTKEKFVKNPFVPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     aSModule        516..3629
                     /complete
                     /domains="nrpspksdomains_ctg21_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg21_1_PCP.1"
                     /domains="nrpspksdomains_ctg21_1_Epimerization.1"
                     /domains="nrpspksdomains_ctg21_1_TIGR01720.1"
                     /locus_tags="ctg21_1"
                     /monomer_pairings="Val -> D-Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       702..743
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0002"
                     /evalue="1.60E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_1"
                     /protein_end="247"
                     /protein_start="233"
                     /score="18.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPID"
     CDS_motif       927..983
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0003"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_1"
                     /protein_end="327"
                     /protein_start="308"
                     /score="33.3"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       1488..1577
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0004"
                     /evalue="1.50E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_1"
                     /protein_end="525"
                     /protein_start="495"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PAGAVGELCVGGDGVARGYLHRPDLTKEKF"
     CDS_motif       1659..1724
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0005"
                     /evalue="1.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_1"
                     /protein_end="574"
                     /protein_start="552"
                     /score="39.1"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        2010..2213
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_PCP.1"
                     /evalue="5.80E-25"
                     /label="ctg21_1_PCP.1"
                     /locus_tag="ctg21_1"
                     /protein_end="737"
                     /protein_start="669"
                     /score="79.2"
                     /tool="antismash"
                     /translation="EEQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRYGL
                     SLQVSDLFRHPKIKDLSPLIRKS"
     aSDomain        2244..3149
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_Epimerization.1"
                     /evalue="2.50E-169"
                     /label="ctg21_1_Epimerization.1"
                     /locus_tag="ctg21_1"
                     /protein_end="1049"
                     /protein_start="747"
                     /score="556.4"
                     /tool="antismash"
                     /translation="GDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALK
                     KLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRISDLSQSESGWETKIKQEVADLQ
                     QSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQ
                     LPPKTDSYQEYARRIQEYAQSSKLIREEAYWRSVEEQQAAELPYEIPHHVNIDFSKRDS
                     LSFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       2256..2282
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0006"
                     /evalue="3.30E-03"
                     /label="NRPS-E1"
                     /locus_tag="ctg21_1"
                     /protein_end="760"
                     /protein_start="751"
                     /score="10.6"
                     /tool="antismash"
                     /translation="WTPVQQWFF"
     CDS_motif       2337..2420
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0007"
                     /evalue="5.50E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_1"
                     /protein_end="806"
                     /protein_start="778"
                     /score="12.4"
                     /tool="antismash"
                     /translation="SGRLSENALRPALKKLAEHHDALRMVYR"
     CDS_motif       2625..2690
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0008"
                     /evalue="1.30E-12"
                     /label="NRPS-E2"
                     /locus_tag="ctg21_1"
                     /protein_end="896"
                     /protein_start="874"
                     /score="39.8"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVSWRILLEDL"
     CDS_motif       3096..3143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0009"
                     /evalue="5.70E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg21_1"
                     /protein_end="1047"
                     /protein_start="1031"
                     /score="27.9"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     aSDomain        3168..3629
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_TIGR01720.1"
                     /evalue="7.50E-53"
                     /label="ctg21_1_TIGR01720.1"
                     /locus_tag="ctg21_1"
                     /protein_end="1209"
                     /protein_start="1055"
                     /score="170.4"
                     /tool="antismash"
                     /translation="ELGTSVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEI
                     SFNYLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAR
                     FHRNTMEQLINRIEHFLLDIMKHCAGQQKAEKTLSDFSSQSLTAEDLDSI"
     CDS_motif       3192..3254
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0010"
                     /evalue="1.20E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg21_1"
                     /protein_end="1084"
                     /protein_start="1063"
                     /score="30.4"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGMLKYL"
     CDS_motif       3294..3323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0011"
                     /evalue="3.90E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg21_1"
                     /protein_end="1107"
                     /protein_start="1097"
                     /score="9.8"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        3678..3767
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_NRPS-COM_Nterm.1"
                     /evalue="2.00E-18"
                     /label="ctg21_2_NRPS-COM_Nterm.1"
                     /locus_tag="ctg21_2"
                     /protein_end="30"
                     /protein_start="0"
                     /score="57.2"
                     /tool="antismash"
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS"
     CDS             3678..10271
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 2e-18.
                     Score: 57.2. Matches aSDomain:
                     nrpspksdomains_ctg21_2_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     1.9e-118. Score: 386.8. Matches aSDomain:
                     nrpspksdomains_ctg21_2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (468-865). E-value: 3e-104.
                     Score: 340.7. Matches aSDomain:
                     nrpspksdomains_ctg21_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1040). E-value: 1.2e-23. Score:
                     75.0. Matches aSDomain: nrpspksdomains_ctg21_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1333). E-value:
                     5e-103. Score: 336.0. Matches aSDomain:
                     nrpspksdomains_ctg21_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1900). E-value:
                     5e-113. Score: 369.6. Matches aSDomain:
                     nrpspksdomains_ctg21_2_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2002-2071). E-value: 1.7e-25.
                     Score: 80.9. Matches aSDomain:
                     nrpspksdomains_ctg21_2_PCP.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 362;
                     E-value: 6.6e-110)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="Condensation (E-value: 3.3e-89, bitscore:
                     286.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.4e-122, bitscore:
                     396.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-17, bitscore:
                     51.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEEDITHLNEAEQSQF
                     IEQWKEKDRDRGFHLQKDVLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNASPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGK
                     SRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR
                     PAEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAYSYHPLYEIQSRSA
                     VKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLMVAPGEEI
                     HIKMNYDAEQNDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQLIGEITDQ
                     TPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQEPVA
                     IMMDRSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSSSLED
                     NYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLLKFEY
                     THSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHQT
                     NIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQNVLRERGIHLHNHYG
                     PSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA
                     RGYVNHDKLTSDKFSSDPFRPGVIMYRTGDLAKRLEDGNIEYIGRADNQVKIRGYRIEP
                     QEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMIP
                     AKWIWVDSIPLTPNGKVDRAALPEPDASISGNPYTAPRNLLEAKLSQLFEDVLKNGHIG
                     IQDNFFDNGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLALIIREAEQNPYAAI
                     EPAEKRDTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELINRHE
                     PLRTSFVSGADDEPVQRIHTEVPFMLSKETTIEGFVRPFDLSQAPLFRAGLIEVSNEKH
                     VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKGDSYQKQE
                     TYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKNRSTLYMT
                     LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNKTFEEFL
                     KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMNDVQLQ
                     WNDLEHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWASLFTTLMEHTAASPE
                     TELDDIQILTKEEERDFIESCHPFEETGYSMNQTLHYALEQQAAKTPDQAAVIFEDGVM
                     TYKELNEQANRIAWELIGRGVKPETTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYP
                     EERISFLLEDSGTNILLLQSASLHIPAFTGEIVYLNQTNSGLAHRLSNPNVNVLPQSLA
                     YVIYTSGSTGMPKGVEIEHRSAVNFLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWW
                     PYAGASVYLLPQGGEKEPEVIVKAIEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRL
                     KRVFSGGEQLGTHLVSRFYELLPNVSITNSYGPTEATIEAAFFDCPPHEKLERIPIGKP
                     VHHVRLYILNQNQQMLPAGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYK
                     TGDVARWLPDGNIEFLGRTDDQVKIRGYRIEPGEIEAALRSVEGVREAAVTVRTDSGEP
                     ELCAYVEGLQRNEVRSQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADA
                     ETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVP
                     LKDVFAHPTVEGLAAVIHEGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGY
                     NMPAVLELEGKLNPERMDRAFKELIKRHESLRTAFEQDAGGDPVQRIHDEVPFTLQTTV
                     LGERTEQEAAAAFIKPFDLSQAPLFRAQI"
     aSDomain        3699..4589
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.90E-118"
                     /label="ctg21_2_Condensation_DCL.1"
                     /locus_tag="ctg21_2"
                     /protein_end="304"
                     /protein_start="7"
                     /score="386.8"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNPQFFQN
                     SINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEEDITHLNEAEQSQFIEQWKEK
                     DRDRGFHLQKDVLMRIALIQTGESQYTCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA
                     SPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGKSRQEHVT
                     FSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI
                     EHMVGLFINTMPVRVQ"
     aSModule        3699..6797
                     /complete
                     /domains="nrpspksdomains_ctg21_2_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg21_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg21_2_PCP.1"
                     /locus_tags="ctg21_2"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3708..3749
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0001"
                     /evalue="1.00E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg21_2"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.3"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       3771..3884
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0002"
                     /evalue="1.50E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg21_2"
                     /protein_end="69"
                     /protein_start="31"
                     /score="49.4"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNPQFFQNSINALVERHDIFRTIFI"
     CDS_motif       4104..4169
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0003"
                     /evalue="5.80E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg21_2"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.8"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       4215..4253
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0004"
                     /evalue="1.40E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg21_2"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.5"
                     /tool="antismash"
                     /translation="PYGKYIKWLMEQD"
     CDS_motif       4488..4583
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0005"
                     /evalue="1.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg21_2"
                     /protein_end="302"
                     /protein_start="270"
                     /score="62.7"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTMPVR"
     CDS_motif       4629..4745
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0006"
                     /evalue="2.10E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg21_2"
                     /protein_end="356"
                     /protein_start="317"
                     /score="65.2"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP"
     aSDomain        5082..6272
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_AMP-binding.1"
                     /evalue="3.00E-104"
                     /label="ctg21_2_AMP-binding.1"
                     /locus_tag="ctg21_2"
                     /protein_end="865"
                     /protein_start="468"
                     /score="340.7"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQ
                     EPVAIMMDRSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSS
                     SLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL
                     KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQNVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTSDKFSSDPFRPGVIMYRTGDLAKRLEDGNIEYIGRADNQVKIR"
     CDS_motif       5268..5309
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0007"
                     /evalue="6.10E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_2"
                     /protein_end="544"
                     /protein_start="530"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPVD"
     CDS_motif       5493..5549
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0008"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_2"
                     /protein_end="624"
                     /protein_start="605"
                     /score="26.7"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVQFEH"
     CDS_motif       5931..5957
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0009"
                     /evalue="5.00E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg21_2"
                     /protein_end="760"
                     /protein_start="751"
                     /score="4.0"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       6066..6155
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0010"
                     /evalue="7.50E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_2"
                     /protein_end="826"
                     /protein_start="796"
                     /score="40.7"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF"
     CDS_motif       6237..6302
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0011"
                     /evalue="7.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_2"
                     /protein_end="875"
                     /protein_start="853"
                     /score="37.2"
                     /tool="antismash"
                     /translation="YIGRADNQVKIRGYRIEPQEIE"
     CDS_motif       6510..6536
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0012"
                     /evalue="5.00E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg21_2"
                     /protein_end="953"
                     /protein_start="944"
                     /score="3.8"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     aSDomain        6591..6797
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_PCP.1"
                     /evalue="1.20E-23"
                     /label="ctg21_2_PCP.1"
                     /locus_tag="ctg21_2"
                     /protein_end="1040"
                     /protein_start="971"
                     /score="75.0"
                     /tool="antismash"
                     /translation="EAKLSQLFEDVLKNGHIGIQDNFFDNGGHSLKATVLMSRIAKEFH
                     VQVSLKDIFAHPTVEGLALIIREA"
     aSDomain        6840..7676
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.00E-103"
                     /label="ctg21_2_Condensation_LCL.1"
                     /locus_tag="ctg21_2"
                     /protein_end="1333"
                     /protein_start="1054"
                     /score="336.0"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC
                     KELINRHEPLRTSFVSGADDEPVQRIHTEVPFMLSKETTIEGFVRPFDLSQAPLFRAGL
                     IEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKK
                     GDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHK
                     NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        6840..9890
                     /complete
                     /domains="nrpspksdomains_ctg21_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg21_2_AMP-binding.2"
                     /domains="nrpspksdomains_ctg21_2_PCP.2"
                     /locus_tags="ctg21_2"
                     /monomer_pairings="Glu -> Glu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6906..7019
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0013"
                     /evalue="4.40E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_2"
                     /protein_end="1114"
                     /protein_start="1076"
                     /score="48.0"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELINRHEPLRTSFV"
     CDS_motif       7191..7256
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0014"
                     /evalue="2.00E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg21_2"
                     /protein_end="1193"
                     /protein_start="1171"
                     /score="29.9"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       7287..7319
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0015"
                     /evalue="3.70E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg21_2"
                     /protein_end="1214"
                     /protein_start="1203"
                     /score="13.2"
                     /tool="antismash"
                     /translation="QYKDYAVWQQK"
     CDS_motif       7578..7667
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0016"
                     /evalue="3.00E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg21_2"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="51.7"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       7716..7835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0017"
                     /evalue="7.30E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg21_2"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="66.6"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        8175..9377
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_AMP-binding.2"
                     /evalue="5.00E-113"
                     /label="ctg21_2_AMP-binding.2"
                     /locus_tag="ctg21_2"
                     /protein_end="1900"
                     /protein_start="1499"
                     /score="369.6"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAAKTPDQAAVIFEDGVMTYKELNEQANRIAWELIGRGVKPE
                     TTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSASLH
                     IPAFTGEIVYLNQTNSGLAHRLSNPNVNVLPQSLAYVIYTSGSTGMPKGVEIEHRSAVN
                     FLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIVKA
                     IEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFYELLPN
                     VSITNSYGPTEATIEAAFFDCPPHEKLERIPIGKPVHHVRLYILNQNQQMLPAGCIGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVK
                     IR"
     CDS_motif       8364..8402
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0018"
                     /evalue="9.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_2"
                     /protein_end="1575"
                     /protein_start="1562"
                     /score="15.7"
                     /tool="antismash"
                     /translation="GILKAGGAYLPID"
     CDS_motif       8589..8648
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0019"
                     /evalue="1.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_2"
                     /protein_end="1657"
                     /protein_start="1637"
                     /score="30.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGMPKGVEIEH"
     CDS_motif       9033..9062
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0020"
                     /evalue="4.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg21_2"
                     /protein_end="1795"
                     /protein_start="1785"
                     /score="6.9"
                     /tool="antismash"
                     /translation="SYGPTEATIE"
     CDS_motif       9171..9260
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0021"
                     /evalue="6.20E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_2"
                     /protein_end="1861"
                     /protein_start="1831"
                     /score="56.8"
                     /tool="antismash"
                     /translation="PAGCIGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       9342..9407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0022"
                     /evalue="1.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_2"
                     /protein_end="1910"
                     /protein_start="1888"
                     /score="39.5"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
     CDS_motif       9603..9629
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0023"
                     /evalue="5.50E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg21_2"
                     /protein_end="1984"
                     /protein_start="1975"
                     /score="3.7"
                     /tool="antismash"
                     /translation="GKLDRNALP"
     aSDomain        9684..9890
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_PCP.2"
                     /evalue="1.70E-25"
                     /label="ctg21_2_PCP.2"
                     /locus_tag="ctg21_2"
                     /protein_end="2071"
                     /protein_start="2002"
                     /score="80.9"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLAAVIHEG"
     CDS_motif       10005..10112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0024"
                     /evalue="1.60E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_2"
                     /protein_end="2145"
                     /protein_start="2109"
                     /score="52.6"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTAF"
ORIGIN
        1 ttcggacgcg cccggagggc gggaagccat tcgtacagta tttgcaggaa gtgcgcgaca
       61 ctgcattgga agcctatgaa catcatgatt atccgttcga agagcttgtc gataagcttg
      121 aattgacaag ggatatgagc cggaatccgc tgtttgatgt gatgtttgtt cttcaaaaca
      181 tggatcagga atcgttggac ctggatgaac tgtgtctcaa acctgcagca aacaatgggc
      241 atcaaacgtc caaatttgat ttaaccctat atgctcagga acagccccac ggtttgctga
      301 cgttccaaat ggagtttagt actgacttat ataagaaaaa aacgatagaa aagtggcttc
      361 aatacttcat caatatgtta ctctccatca tccaggacaa caaagccgtt ctcggaacaa
      421 taaatatcct gaatgaagat gaggcccatt accttatcca tgaactcaat cgtacaaaaa
      481 tggattatcc aagaaatgaa accatcagca gactctttga aatgcaggcg gaacaaacgc
      541 ctaatgccat agcgattgtc agcgatacac aagagttaac ttacgcggac ctgaacaact
      601 gggcaaatca aattgcttca gttctacaga gaaagggagt cggtcccgat cgagtcgtag
      661 ccttgttggc aggacgaacg ccagaactca tagcaggtat gctgggcatt ctgaaagccg
      721 gaggagccta tctgcctatc gattctaatc tgcctgttga acgcatagct tatatgctgt
      781 ctgacagcag ggcagcatta ctccttcaat ctgaaaaaac agaaaaacgg ctattaggca
      841 ttgaatgtga acaaatcata atcgaagata ttcaaaagca aggagaggcg aagaacgttg
      901 aatcttcagc agggccccat tcacttgcat atatcattta tacctctgga tcaaccggta
      961 aaccaaaggg tgtcatgatt gagcagcgaa gtgtcattcg tcttgtaaaa aacagcaatt
     1021 atattacgtt tacaccagct gaccgccttc tgatgacatc atcaatcggt tttgacgttg
     1081 gatcatttga attttttgga ccgctgttaa atggtgccgc tttgcacctg tccgatcaac
     1141 aaacctttct cgattcccaa cagcttaaga gatacataga acatcaagga atcacaacga
     1201 tgtggctgac ctcgtctcta ttcaatcatt tgacagagca actcgagaca acattttcgc
     1261 agcttaacca tctgatcata ggcggagaag ctttgtcggc aagccacgtc aatcgaatca
     1321 gaaatgcctg cccggaagta tcgatatgga acggatatgg gccaaccgaa aatacaactt
     1381 tttcgacatg cttccacatt caaaaaacat atgaactctc cattccgatc gggcggccgg
     1441 taggcaattc ctccgcttat atcttaaatc aatggggaat gctgcagccg gccggagctg
     1501 tcggcgaact ttgtgtcggc ggagatggcg ttgccagagg gtatttacac cgtcctgatt
     1561 taacgaaaga gaaatttgtc aaaaacccat ttgtacccgg cgatcgactg taccgcacag
     1621 gtgatctggc gcgctggctt cccgatggca caattgagta cgttggccgt attgatgatc
     1681 aagtaaaagt cagaggctat cgggtagagc tgggcgagat cgaatcagca cttcgccaca
     1741 tagacggagt caaagaagcg gcggtgttgg cccgtacagg acagtcaggg agcaaagagc
     1801 tgtttggcta tatcagcgta aaagcgggca cgaatgctga acaagtgcgt tctcttctcg
     1861 cccgttcact gcctaattat atgattccgg cgtatatcat tgaaatggag aatcttccgc
     1921 tcacatcgaa cggcaaattg aaccggaaag cactgcctga accagatttc gcatctaaac
     1981 aaacatacat cccgccacgc aacgaacttg aagagcagct ggcattgatc tggcaggagg
     2041 ttctaggcat ccagaggatc ggaatagagg attcgttttt tgaattgggc ggagattcaa
     2101 tcaaagccct tcaagtttct gcacgccttg ggcgctatgg actaagcttg caggtaagtg
     2161 atttattccg tcatccaaag ataaaggact tatcaccatt gatccgtaag tcagagagaa
     2221 tcatagagca aggacccatt cagggtgacg ttccttggac gcctgttcag caatggtttt
     2281 tttcacaaga tattgaagaa agacaccatt tcaatcagtc tgtcatgcta ttccattctg
     2341 gacgtttgtc tgaaaacgcc cttagaccag ccttgaaaaa actggcggag catcatgatg
     2401 cgcttcggat ggtttatcgc aacgatgaca ggcgatggat tcaaatcaac caaggcattc
     2461 atgagtcaca gctatacagc ttaagaatct ctgatctttc acagtcagaa agcggctggg
     2521 agacgaaaat caaacaagaa gttgccgatc ttcagcaaag catcaatttg caggaaggac
     2581 cattgttgca cgccgctttg tttaaaacac tgaccggaga ttacttgttc cttgcgatcc
     2641 atcaccttgt cgttgatggt gtctcatggc ggattttgct ggaggatttg tcagccggat
     2701 atcaacaagc tgctgcaggc cagacgatcc agcttccgcc taaaacggat tcctaccagg
     2761 aatacgcaag acgcatacag gaatatgccc aaagcagtaa gctgattcgc gaagaggcgt
     2821 attggcgaag tgtagaagaa cagcaagccg cagaactgcc ctatgaaata ccgcatcatg
     2881 tgaacatcga cttcagcaaa agggactcat taagcttttc actgactgaa gcagacaccg
     2941 ccgtcttgct gcaaaacgtc aatcacgcct atggcacaga tacacaagat attctgttaa
     3001 ccgcagcatc cttggcgatt tgtgaatgga caggaggaag caagctccgt atcgctatgg
     3061 aaggacacgg gagagaacac attctaccag agttagatat aagcaggacg gtcggctggt
     3121 ttacatccat gtacccggcc ctcataagct ttgaaaatca tagggatgag ctcggaacct
     3181 cagtaaaaac cgttaaagat acactgggcc ggataccaaa caaaggggta ggttacggta
     3241 tgctgaaata ccttacacac cctgaaaata aaagcattac gttttcaaaa acacctgaaa
     3301 tcagctttaa ctatttgggc cagttcaacg acatcgaaag acaggacacc ttccgcccat
     3361 caagccttgg tagcggaaag gatatcactc atacatggaa gcgcgagcaa atcatcgaga
     3421 tgagtgcaat ggcagcagac aaaaagctcc atttcaatct tagttatccg ccagcccgct
     3481 ttcacagaaa cacaatggaa cagcttatta acaggattga acactttttg ctggacatta
     3541 tgaaacactg cgccggtcaa cagaaagcag aaaagacact gagcgatttc agcagtcaat
     3601 cattaacggc agaggacttg gacagcataa ccagcttggt ggaagaattg tagaaaatcg
     3661 tgacaggaga catgaacatg acaaaagcga attcaattca ggatatttat ccgctgtctt
     3721 acatgcagga agggatgctt ttccattccc tcctgcaaaa agattcacag gcgtatgttg
     3781 agcaagcttc ttttacaata gaaggaaaag tcaacccgca gttttttcaa aacagcatca
     3841 acgctcttgt agaaagacat gatattttca gaacgatttt tatcagccaa aatgtttcct
     3901 ccccccagca ggttgttctg agagaacgaa atgtcatcgt actggaagaa gacattactc
     3961 atttaaacga ggcggagcaa tcacagttta tcgagcaatg gaaagaaaag gaccgggacc
     4021 gggggtttca tttgcaaaag gatgtgctca tgcgcatcgc tctgattcaa acaggagaga
     4081 gccagtacac ttgtatttgg acctttcatc acatcatgat ggacggttgg tgcctcagca
     4141 ttgtgctaaa ggagtttctg catatttacg catcttatgt aaatgcatcc cctataacat
     4201 tggagccggt ccagccatac ggaaagtata tcaaatggct gatggagcaa gacaaagagc
     4261 aggcggtttc ttattgggac cattatcttt ccggccacga acagcaaacc gtgctcccga
     4321 agcagaaaaa aacaaaggga aaaagcaggc aggaacacgt tacattttca ttctctaagg
     4381 aagaaagcag caggctttca gagcttgctg caagagaaga agtgacactc agtacgattt
     4441 ttcataccat ttggggcatt ctgctacaaa aatataataa taacgatgac gccgtattcg
     4501 gttctgtcat ttcaggaaga cccgcagaaa tcgaaggcat tgaacatatg gtaggtcttt
     4561 tcattaatac gatgccggtt cgggtgcagg gggcaaaaac gccatttctt caacttataa
     4621 aagatatgca aaaagaccgt cttgccgctg aagcgtacag ctaccaccct ttatatgaga
     4681 ttcaatcccg ctcagctgtt aaacaagggc tgattgatca tattctcgta tttgaaaact
     4741 atccggtgca gcaagagatt caaatgctga acaaacagga acatgcttct gatctttttc
     4801 agattcataa tttcactgtc gcagatgaaa ccaactacag cttttacctt atggtggcgc
     4861 caggggaaga aattcatatc aaaatgaact atgatgcgga gcagaacgat cggtcttttg
     4921 tgctctctgt caaagagcat cttctgaatg ctgtatcaca aatcttaaat aatccgaatc
     4981 ttccacctga agaaatcgat atcacgacag atactgaaaa gcggcagctg attggagaaa
     5041 tcacagatca aacaccagtt tacgaaacca tccatgccat gtttgaaaag caagcggaaa
     5101 agacaccaga tgctcatgct gtaattgatc aagcctgctc attaacatac agagaactga
     5161 ataaagcggc taacagattg gcacggcatt tacgaatgaa aggcgttgtg agacaggaac
     5221 ccgttgcgat tatgatggat cgctctgcgg cgtttatcac aggtgttctt ggtatcttaa
     5281 aggcaggcgg cgccattgtt ccggttgatc cgcattaccc ggctgacaga atccgttata
     5341 ttctgcatga ttgcggctgt tcgcatgttg tttcacaagc gcatctttcc tcatcgttag
     5401 aagacaatta cattatcact catccagaag atatcgaaag caaagtagac ggcagtaaca
     5461 taaagtcagt caacaatgct gacgatctgc tgtatatgat ttatacatca ggcacaacag
     5521 gtaaaccaaa gggtgttcaa tttgagcatc gaaacatggc taacttgctg aagttcgaat
     5581 atactcactc cggcattgac tttgaagcag atgttctgca atttgcgacg ccttcattcg
     5641 acgtctgcta tcaagaaata ttttctgcgc ttctgaaagg cggcacactg cacatcgtgc
     5701 cagaagccat aaaaagagat gtgcctcagc tgtttgcgtt tataaacaag catcagacga
     5761 atattgtgtt tctcccaact gcttttatca aaatgatttt cagcgagcga gaacttgcga
     5821 actcgtttcc tgatggcgtc aaacacctga tcgcagccgg ggaacaatta atgatttcag
     5881 accttttcca aaatgtgttg cgtgaacgcg gcatacacct gcacaatcat tacggacctt
     5941 cagaaactca tgtggtatct acgtatacca ttcatcctgg agaccctatt cctgagcttc
     6001 cgccaatcgg taaaccgata ggctgtactg atctatatat tttgaatcat caaaaacagc
     6061 ttcagccatg cggcgtacca ggcgaactct atatttccgg cgcaagtgtt gccagaggat
     6121 atgtcaatca cgataaactg acaagcgaca aattttcatc cgacccattc aggcctggtg
     6181 tgatcatgta ccgtacaggt gatttggcca aacggcttga agacggcaac atcgaatata
     6241 tcggacgggc agacaatcaa gtgaaaatca gaggttatcg aatcgagccg caagaaatcg
     6301 aagtcacgtt aatgaatcat ccggacatta gtgaggctgc cattctcatc tggcaagatc
     6361 aaaacggtga acatgaatta tgcgcttact attgcagtgt acaaaagctg aatgcaatag
     6421 atttacgcag ttatatggct agtgagctcc cagaatacat gattccggcg aaatggatat
     6481 gggttgacag catacctctt accccaaacg gaaaagtaga tcgcgcagca cttccggagc
     6541 cagatgcttc aatcagcgga aacccatata ctgcccctcg aaatctgtta gaggcaaagc
     6601 tttcgcaact atttgaagat gtgctaaaga atggacatat aggcatccaa gacaactttt
     6661 ttgacaatgg cggtcactcg ttaaaagcaa cagtgcttat gtcacggatc gcaaaggaat
     6721 tccatgtgca agtttcgctt aaggacatct ttgctcatcc gactgttgaa ggattagctt
     6781 taatcattcg agaggcagaa caaaatccgt atgcagcaat tgaaccagca gaaaaaaggg
     6841 atacatatcc tgtatcttcg gcccaaaaac gaatctatgt gcttcaacag cttgatgagg
     6901 gtgtcgccta taacatgcct gcggtcttag aactggaagg tgcactggat gtcgccaaac
     6961 tgtctgctgt atgtaaagaa ctgatcaatc ggcatgagcc gcttcgaact tcctttgtat
     7021 ctggagctga tgacgagccg gttcagcgta tccacaccga agtgccgttt atgttaagta
     7081 aagagaccac tatcgaggga tttgtccgtc cctttgatct tagccaggcg ccattattta
     7141 gagcaggcct tatagaagtg tcaaacgaga agcatgtatt gctggtggat atgcaccata
     7201 tcatttcaga tggcgtatcc gttcagctcc taatccgaga atttaccgat ctttatgcaa
     7261 accggcagct taagccattg cggatccaat ataaagatta cgccgtatgg cagcagaaat
     7321 ttaaaaaggg agactcgtac caaaagcagg agacttactg gcagcagcag tttagcgggg
     7381 accttcctat actagagctt ccaacagata aacgacgtcc ggcagaacgg caattcatag
     7441 gcggaaaagt aacctttcaa ttggacaaag agatcacggc ccgcataaag cggctcgccc
     7501 ataaaaacag aagcacgctt tatatgacgc ttctcgcttt gtattcagcc tttttgtctc
     7561 ggttaagcgg tcaggatgat atcgtgattg gttcacctat cgccggacgg ccccatgccg
     7621 accttgaagc tgttcttggg atgttcgtca atacattggc tctccgtaca cgcccggcgg
     7681 gtaataagac atttgaggaa tttctgaaag aagtcagaca gacggcacta gaagcgtatg
     7741 agcatcagga ttacccgttt gaagagcttg tggacaaact cggtgtgcag cgggaaatga
     7801 gccggaatcc tttgtttgac acaacgctag tccttcagaa tatggaacag caaaagctaa
     7861 aaatgaatga tgtacagctt cagtggaacg acttggagca cccaatatca aaatttgata
     7921 tttccctata cgttacagag catgattccg agcttttctg tcagtttgaa tacagtacag
     7981 ctttgtttga gaaagaaacc atccaaaggt gggccagcct tttcaccacg cttatggaac
     8041 atacagctgc cagccctgaa acagaattgg acgatattca aatcttaaca aaagaagaag
     8101 agagagattt cattgaatca tgccatccgt ttgaggagac gggctattca atgaatcaaa
     8161 ctctccacta tgcactcgaa cagcaggcag caaaaacgcc tgatcaggcg gccgttatct
     8221 tcgaagatgg agtgatgacc tataaagaat tgaacgaaca ggctaaccgt atcgcctggg
     8281 agctgatcgg acggggggta aaacccgaaa cgactgtggc cattatagga aagcgttcac
     8341 ctgaaatgct gcttggcatt tatggcattc ttaaagctgg cggcgcttat ctgcccattg
     8401 acccggatta tccggaagaa cgaatcagct ttctgctgga ggacagcggt acaaacattc
     8461 tcctgcttca gtctgccagc cttcatattc cggcatttac aggagagatt gtctatctca
     8521 atcagacaaa tagcggactg gcacatcgtt tgtccaatcc gaatgtgaac gttctcccgc
     8581 aatctttagc ctatgtcatc tatacatccg gctctaccgg gatgcctaag ggtgttgaaa
     8641 ttgaacatcg atcagcggtg aattttttga attccctaca gtcccgctat cagctaaagc
     8701 attcagatat gattatgcac aaaacatctt attcattcga tgcttcaata tgggagctgt
     8761 tttggtggcc ttatgccgga gcttctgttt atctgcttcc tcaggggggc gaaaaagaac
     8821 ctgaagtgat cgtgaaggcc atagaagaac aaaagatcac agctatgcat tttgtgcctt
     8881 caatgctcca tgcattttta gaacatataa aatatcgctc tgtaccgatt aagacaaaca
     8941 gactcaagcg agtattttct gggggagaac agctggggac ccatcttgtc tcccgatttt
     9001 acgagttgct tccaaatgtt tcaataacca attcctatgg gccaacggaa gcaaccatag
     9061 aagctgcatt ctttgattgt ccgccgcatg aaaaacttga acggattcca attggaaaac
     9121 ctgttcatca tgtcagatta tatatcctga atcagaatca gcagatgctg cctgctggat
     9181 gtatcggcga actgtacatt gccggagcgg gtgttgccag aggttatttg aatcggccgg
     9241 cattaacgga ggagcgtttt cttgaggacc cgttttaccc gggggaacgc atgtacaaaa
     9301 ccggggatgt ggcgcgctgg ctccctgacg ggaatattga attcctcggg cgcacggatg
     9361 atcaggtgaa aatccgcggc taccggattg agccgggaga aattgaagcg gcactaagaa
     9421 gcgttgaagg cgtaagagag gcggccgtta ccgtacggac agacagcggg gagccggaat
     9481 tatgcgctta tgtagaaggg ctccaaagaa acgaagtgcg gtcacagctt gagagactgt
     9541 tgccgggcta catggtccca gcctatatga tagagatgga acagtggccg gttacgccaa
     9601 gcggaaagct tgaccgaaac gccctgccag ctcctggcgg agcggcagat gcggagacct
     9661 acacagcgcc gagaaacgtg actgagatga agctttctca gctgtgggag gacgtgctga
     9721 aaaatggccc tgtcgggatt cacgacaact tttttgaccg cgggggacat tccttaaaag
     9781 caacggcgct tgtctcacgg atcgccaaag aattcgatgt acaggtgccg ctaaaagatg
     9841 tgtttgccca tccgacagta gaaggactgg cggccgttat ccatgaagga acggacagtc
     9901 catatgaagc gattaagccc gctgaaaaac aggaaaccta tccggtttcc tctgcccaaa
     9961 agcggattta tgtccttcag cagctggagg acggagggac aggctacaat atgccggctg
    10021 tgttagagct cgaagggaag ctcaaccctg aaaggatgga cagagctttc aaagagctga
    10081 tcaagcgcca cgagtcgctt cggaccgcct tcgaacagga cgcaggaggc gatccggtgc
    10141 agcgcatcca tgacgaggtg ccgtttacgt tacagactac agttctcggc gaacgaaccg
    10201 aacaggaggc cgcagccgca tttatcaaac cgtttgatct cagccaagcg ccgctgttcc
    10261 gtgcccaaat cg
//
