LOCUS       gnlProkkaEAENIOAH_28    1612 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EAENIOAH_28.
ACCESSION   gnlProkkaEAENIOAH_28
VERSION     gnlProkkaEAENIOAH_28
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:26:57
            Original ID  :: gnl|Prokka|EAENIOAH_28
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 1612
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..1612
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:1612]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..1612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..1612
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..1612
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             2..1612
                     /NRPS_PKS="Domain: AMP-binding (1-362). E-value: 2.9e-102.
                     Score: 334.2. Matches aSDomain:
                     nrpspksdomains_ctg28_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (464-533). E-value: 2.9e-26. Score:
                     83.4. Matches aSDomain: nrpspksdomains_ctg28_1_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 331;
                     E-value: 1.7e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg28_1"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-120, bitscore:
                     388.3, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-18, bitscore:
                     53.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVTNESIVGILSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERL
                     SYMLKDSGASLLLTQPGCSAPSFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYT
                     SGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWTLSGA
                     SAYLLPPGWEKDPALIVQAIHQEKVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAG
                     GEPLAPRTAARFASILPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGA
                     HLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDV
                     ARWLPDGNIEFLGRLDDQVKIRGYRIEPGEIEAALRSVEGVREAAVTVRTDSGEPELCA
                     YVEGLQRNEVRSQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYT
                     APRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDV
                     FAHPTVEGLAAVIHEGTDSP"
     aSDomain        5..1087
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_AMP-binding.1"
                     /evalue="2.90E-102"
                     /label="ctg28_1_AMP-binding.1"
                     /locus_tag="ctg28_1"
                     /protein_end="362"
                     /protein_start="1"
                     /score="334.2"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="GVTNESIVGILSERSPEMLIAVLAVLKAGGAYLPLDPAYPKERLS
                     YMLKDSGASLLLTQPGCSAPSFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTS
                     GSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWWTLSGAS
                     AYLLPPGWEKDPALIVQAIHQEKVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGG
                     EPLAPRTAARFASILPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGAH
                     LYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVA
                     RWLPDGNIEFLGRLDDQVKIR"
     aSModule        5..1600
                     /complete
                     /domains="nrpspksdomains_ctg28_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg28_1_PCP.1"
                     /locus_tags="ctg28_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       71..112
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg28_1"
                     /protein_end="37"
                     /protein_start="23"
                     /score="20.2"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       296..355
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0002"
                     /evalue="2.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg28_1"
                     /protein_end="118"
                     /protein_start="98"
                     /score="35.5"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       881..970
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0003"
                     /evalue="2.90E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg28_1"
                     /protein_end="323"
                     /protein_start="293"
                     /score="57.9"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       1052..1117
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg28_1_0004"
                     /evalue="2.50E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg28_1"
                     /protein_end="372"
                     /protein_start="350"
                     /score="41.7"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     aSDomain        1394..1600
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg28_1_PCP.1"
                     /evalue="2.90E-26"
                     /label="ctg28_1_PCP.1"
                     /locus_tag="ctg28_1"
                     /protein_end="533"
                     /protein_start="464"
                     /score="83.4"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLAAVIHEG"
ORIGIN
        1 acgcggcgtc acaaacgaaa gtatcgtcgg tatcctgtct gaacgctcac ctgaaatgct
       61 gatcgctgtc cttgctgtct tgaaggcagg aggggcctat ttgccgcttg atcctgcgta
      121 tccaaaggag cggctgagct acatgctgaa agacagcggg gcatcactct tgctgacgca
      181 gccgggatgc tccgcaccga gcttttctgg agagacgctt gaagtggaca tgacatctct
      241 tgcgagcgaa aaagcagaaa accatgagtt tactcctgct gacggcggat ctctcgccta
      301 tgtcatctat acatcgggct ctaccgggca gccgaaagga gtggccgttg agcaccgcca
      361 ggctgtttcc tttctgaccg gcatgcagca ccagtttccg ctttcggaag atgacattgt
      421 catggtgaaa acctcttttt cctttgatgc gtctgtgtgg cagctgtttt ggtggactct
      481 ttccggtgct tcggcgtatc tgcttccgcc cggctgggaa aaagaccccg cgttgatcgt
      541 acaagccatt catcaggaaa aagtgacaac ggctcatttt attccggcta tgctgaacag
      601 ctttctcgat caagcggaaa tcgaaaggct gagtgacagg acaagcctga aacgtgtatt
      661 cgccggaggt gaaccgcttg cgccccgtac cgcagcccgt tttgcttcta tcttgccgca
      721 ggtatcatta atccatggtt acgggccgac agaagcaacg gtagacgcgg cattttacgt
      781 attggaccca gaacgggaca gggaccgctt gcggattccg atcgggaagc ccgtacccgg
      841 tgcgcatttg tatgttttag atccgcattt agccgtacag ccttctggtg tcgccggcga
      901 actgtacatt gccggagcgg gtgttgccag aggttatttg aatcggccgg cattaacgga
      961 ggagcgtttt cttgaagacc cgttttaccc gggggaacgc atgtacaaaa ccggggatgt
     1021 ggcgcgctgg ctccctgacg ggaatattga attcctcggg cggttggatg atcaggtgaa
     1081 aatccgcggc taccggattg agccgggaga aattgaagcg gcactaagaa gcgttgaagg
     1141 cgtaagggag gcggctgtga ccgtacggac agacagcggg gagccggaat tatgcgctta
     1201 tgtagaaggg ctccaaagaa acgaagtgcg gtcacagctt gagagactgt tgccgggcta
     1261 catggtccca gcctatatga tagagatgga acagtggccg gttacgccaa gcggaaagct
     1321 tgaccgaaac gccctgccag ctcctggcgg agcggcagat gcggagacct acacagcgcc
     1381 gagaaacgtg actgagatga agctttctca gctgtgggag gacgtgctga aaaatggccc
     1441 tgtcgggatt cacgacaact tttttgaccg cgggggacat tccttaaaag caacggcgct
     1501 tgtctcacgg atcgccaaag aattcgatgt acaggtgccg ctaaaagatg tgtttgccca
     1561 tccgacagta gaaggactgg cggccgttat ccatgaagga acggacagtc ca
//
