LOCUS       gnlProkkaICEJKCOP_29   10518 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICEJKCOP_29.
ACCESSION   gnlProkkaICEJKCOP_29
VERSION     gnlProkkaICEJKCOP_29
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:24:42
            Original ID  :: gnl|Prokka|ICEJKCOP_29
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5120
            Orig. end    :: 15638
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10518
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5518]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5518
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10518
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10518
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(3..188)
                     /locus_tag="ctg29_9"
                     /transl_table=11
                     /translation="MSFRKMSSFIVGGGFLFAIVWLILSDLDLLPHISFIDRYYLIFLV
                     IFIVVCEKSQKNKPTN"
     CDS             complement(392..661)
                     /locus_tag="ctg29_10"
                     /transl_table=11
                     /translation="MTKSKKSQRMIMILALSAIQVMILSILYRIINPKEFASMIYQVNA
                     NNTMRFVIIAVILFTFIASMISSSLLVSVFDFLRSGLFKKGNSK"
     CDS             complement(772..1629)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_11"
                     /sec_met_domain="Abi (E-value: 1.8e-12, bitscore: 38.8,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKAGFVNLDEGDGMEKKRQRLFTPGLRVLYIFILDEFIEAFVF
                     TPFLSFLQLDFWADIVLYKVLSLVIILGLNLLLLRQKIIFRTSFGWPSWQKFVFWDIVG
                     CLVAWQIFTNRNFLDILQASVIGTIAAVPEEYLYRGVIFGGLLRAFYLANRGGTKRNFL
                     YCMLLSSLAFSLAHLSNLPSQGAVATVGQMIQVSGMGMLLAALYVRYGTLLMPIFVHFM
                     IDCLVTLIHGPYPSKLNGVSDEATLITVSLIWATIYLAISMWVLWHCHDEEGFMARLAG
                     QAIK"
     CDS             complement(2142..2474)
                     /locus_tag="ctg29_12"
                     /transl_table=11
                     /translation="MNMIQRNKVYFIMTGLNESFQKTATVSVMNTDAQEVIDDALHILE
                     KENVLQNRAIDYALARLYSRFVRLIGLQGMKLSPEADQWWQQLKNFMENDIHEELSQVG
                     GPHFIT"
     CDS             complement(2726..2911)
                     /locus_tag="ctg29_13"
                     /transl_table=11
                     /translation="MTLNKAIHYLLLIGISGVFLFTLAAAMGWVNQGDFALPLLLLAAG
                     LTLLRETDAGYEKARH"
     CDS             complement(3236..3571)
                     /locus_tag="ctg29_14"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSKAYANPTIKAEPALRALIETNAKKVDEGDDEK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAARYRAQALAAGLVA
                     IPIVWGH"
     CDS             complement(3690..4286)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 109.3;
                     E-value: 3.3e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_15"
                     /sec_met_domain="Mac (E-value: 8e-11, bitscore: 33.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRELVGQTGVKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGDHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMI"
     CDS             complement(4557..4865)
                     /locus_tag="ctg29_16"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             complement(5001..5216)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_17"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.8e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(5213..5518)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_18"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 9.9e-15,
                     bitscore: 46.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVKDSKVDLTQNNLLPFEEKRKIMSYNYRQLDDFQLSGVSGGKK
                     KFDCAATFVTGITAGIGSGTITGLAGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(5718..6671)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     221.6; E-value: 2.1e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_19"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADSTLTRQEWYDIYFAAGNDLP"
     CDS             6876..7610
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 3.9e-12. Score:
                     38.3. Matches aSDomain: nrpspksdomains_ctg29_20_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.9; E-value: 1.1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_20"
                     /sec_met_domain="adh_short (E-value: 8.4e-35, bitscore:
                     111.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        6894..7382
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_20_PKS_KR.1"
                     /evalue="3.90E-12"
                     /label="ctg29_20_PKS_KR.1"
                     /locus_tag="ctg29_20"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       6897..6977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg29_20_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg29_20"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             7636..8799
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     289.8; E-value: 4.6e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_21"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTPAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKMIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIAALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRNHVAGAFPVIVVGGIKTPADAEKAAESFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     FQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSVTSSNVTQD"
     CDS             complement(9061..10323)
                     /locus_tag="ctg29_22"
                     /transl_table=11
                     /translation="MPMPVIRALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALP
                     DEKLQKDFPLHVYQTGSGTQTNMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFP
                     TVMNITSAIAVNQLLHAVNQLCSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWV
                     AMMEHDQIALKRLQPNLFYLAIGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNK
                     FAALAAHSEISVVHGAIKTLAADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPG
                     KVNPTQAEALTMAAVRVMGNDTTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTS
                     FTEKLAAGLTIHAPHMRALVDHSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIK
                     SGDVTAAQFDKWVDPLKMTRA"
ORIGIN
        1 gcttaatttg taggcttgtt tttttgactc ttttcacaca ccacaataaa aataacgaga
       61 aagatcaaat agtagcgatc aataaatgaa atgtgaggta acaaatctag atcacttaaa
      121 atcagccaaa ctatagcaaa taaaaagccg ccaccaacaa taaagctgct catttttcta
      181 aaactcataa acagacccac tctctatcat tcttcaatgt ttatttttgc aataatacaa
      241 acgtttcatt tgccaattga ggagattaaa tgcatataga catcatgatc cgctgacttg
      301 aattatctgt tcaacagttg caataacacc ttggtctggc aaagtgttta agtgtgcacg
      361 agaaaacgaa agtcatattc acagatgaaa atcatttaga gtttcctttt ttgaataaac
      421 cactcctcaa aaaatcgaat acagacacca aaagagacga gcttatcatg ctcgctataa
      481 aggtaaacaa tatcacggct atgataacga atctcattgt attgttagcg ttgacttgat
      541 aaatcataga agcgaattct tttggattta taatcctgta cagaatactg agtatcatta
      601 cctgtattgc tgacaaagca aggatcataa tcattctttg acttttttta gatttggtca
      661 cttgattcag ctcctctttt ttggatcttc ctataattaa ataagcgatt atcatatcca
      721 gtaataaagt tttccgcaat tgcgagtgaa tgtgtccaag atactataaa cttatttgat
      781 tgcttggcct gctaaccttg ccatgaaccc ttcttcgtca tgacagtgcc ataggaccca
      841 catggaaatg gccaagtaaa tcgtagccca gatcaacgaa acagttatga gcgtcgcttc
      901 gtcacttacc ccatttaatt tgctaggata agggccgtga atcagcgtta ccaagcagtc
      961 gatcatgaaa tgaacaaaaa tcggcatcag taatgtgcca taacgaacgt agagagcagc
     1021 cagcagcata cccatcccgc tgacttgaat catctgaccc acagttgcaa cagcaccttg
     1081 gcttggcaga ttactcaagt gtgcaagcga aaacgccaga ctgcttagta acatgcaata
     1141 gagaaagtta cgtttggtac caccacggtt agcaaggtaa aaggcgcgga gcaatccacc
     1201 gaaaataacc ccgcgataca ggtactcttc aggaacagcg gcgatggtac caatgacact
     1261 tgcttgtaaa atatctagga agtttcggtt ggtaaagatt tgccaagcta caaggcagcc
     1321 cacaatatcc cagaacacaa atttctgcca gcttggccag ccaaatgacg tcctaaagat
     1381 aatcttttgt cttaacagca acagattgag ccccagaatg ataactaaac taagtacttt
     1441 atagagcaca atgtctgccc aaaaatccag ctgtagaaaa cttaaaaatg gggtgaacac
     1501 aaatgcttct ataaattcat ccaagataaa aatgtataaa acccgtaatc caggcgtgaa
     1561 caaccgttgc cgtttctttt ccattccgtc accttcatcc aagttgacaa agccggcttt
     1621 ttccgacatt gctatgaaca atataccggt taatgaatgg cttttagtca actaatttta
     1681 aacgtcgtgt tttcgccatt taacgttgac gatcatccgt caaaaattcg ctagcgatca
     1741 tttattgaca aaaaaagcca cttcactcgg caaacgacgc tacgctaagc caagaagaag
     1801 tgacgctgca gtgttgaaaa agtcgcggag cttgcaattg gcgcaattct tcaccggtca
     1861 caaacaccta catgccctgc catcccttta aaaaccccgc aataatttgg tcagtgtgtg
     1921 accaagcatc tatcgcaatc aatcctaaaa tcagcattgt caggaattta cgtcaggtca
     1981 tcccgtcaat catttgttgc aaatcatcat tctttattcg atgcatctca tcgtgctcct
     2041 tccccaacca gtctaaatca agtggtaagt cacagtataa acagcgtaac actcgacttc
     2101 cgacttcgca tttgcatgtg ccaatattgg gaacaaaccg atcaagtaat gaagtgcggt
     2161 ccgccaacct gactcagctc ttcatgaata tcattctcca taaaattttt cagttgttgc
     2221 caccactgat cagcttctgg ggataatttc atcccctgta ggccaattaa gcgaacgaac
     2281 cgagaataca ggcgcgctaa tgcgtaatca atggctctat tttgaagcac attttctttt
     2341 tccaaaatat gtagcgcatc atcaatgacc tcttgtgcat cggtattcat gacactgacg
     2401 gttgcagttt tttgaaagct ttcgttgagc cctgtcataa taaaatagac tttatttcgc
     2461 tgaatcatgt tcataatatg tcaccattcc ttttgatgtc gtgacaattt ttctatagaa
     2521 atgtttgaaa agtatcgatg ctatggcttt taggcaaagc accggaaaac aatggcttta
     2581 tagcctgact gatggatctt gataccgtct tgtatctgaa ctcttttaga tatgagtcat
     2641 cgtaaccgat tacattttaa aatcagtttg tccttgtgta cagaaattcg gcttcacgtt
     2701 tttctgcctt ctaagcagac ccaattcaat gcctcgcttt ttcatatccg gcatcagttt
     2761 cccgcaacaa cgtgagtcct gccgccaaaa gcagtagtgg cagcgcaaag tcaccttggt
     2821 tgacccagcc catggcggca gccagcgtaa aaagaaagac accactgatg cctatcagta
     2881 aaagataatg aattgcttta ttcaacgtca tcgccaactt gtatcccccc gtccagatga
     2941 acttcgactt tttctcgcgg atgcttttac gcacactata ctggatagtt cacacaacag
     3001 cgcaaacttt ttttaaacgt agggttttgc ccgattaacg tcgctttttt gtcaaatatc
     3061 gaccaaattt tctctttatc gatctgctac tcggtttttc ttaactggtg tcaacaagtt
     3121 tcatggcaaa aaaatagccg cagatcttag tctgcgacgt ttttttgcaa atgataactg
     3181 attgcttgat catcaacttt agcctcaccg tttaaaattc acagttgtac atcggctaat
     3241 gcccccaaac aatgggaatg gcaactaagc cagcggccaa ggcttgcgcg cgataacgtg
     3301 ctgcatcaat atcggcagca ggtacatctt ttttgatgta attgaagacg gccaccagct
     3361 cttctggtac ggcgtgatga atcagatagt atttggaaat gtcgtgggac aactgagtga
     3421 cagccgtcac ataagccttt tcgtcatcac cttcatcaac ctttttggcg ttggtttcga
     3481 taagcgcccg taatgccggc tctgctttga tcgttggatt agcgtatgcc ttgcttagca
     3541 tcgacattaa agtttcacgt ttgtctgtca tcctgcactt cctttcgatg attaacttgg
     3601 caattcatgc tcactcggag caccttagtc tttgtgaata ttgttaggat gcgcttgtcg
     3661 attgttaatt tcaagtatcg atttggcgtt tagatcatgt catgccctgc aaaccctgtt
     3721 ttatcagcag ccgtgatctc gcgcagcact tcgcaaggat tacccgccgc aatcacgcgc
     3781 gctgggatgt cgtgggtgac aacactacct gccccgataa tcgtccccgc accaatcgtg
     3841 acgccgggta gcaccgtcac attggcagcg agccaacagc catccccgac tacaatcggt
     3901 ttagcaatgc agccaccaag ttgtcgttca agtggatcaa aaaggtggtt gctggtgtac
     3961 aaaccgactt tcgggccaaa caaaacgtga tcgccaatgg tcaccggcgc cccgtccaaa
     4021 atggtacagt cataattggc ataaaaatga tcacctacgc ggatattccg gccaaactca
     4081 caatgaaagt ttggattcac aaacggtttg acgccagttt ggcctaccaa ttccctaaac
     4141 aaggcattgc gtttggctgg atcgtgttca ttgttaagcg catcagtttt ggcagttgct
     4201 tcatcccgca cagccagtaa caaagggtcc atgtcgtcgt atggcttacc agttgccatg
     4261 aaagcaaatt tttcttctag attcattgcg ccacccctct ttcttggctc aagtttacca
     4321 gacatttgcg cactgcgttg ataattgcca atatgttaag gtgtgcttat cggtacgcat
     4381 gaagtctaca aaaagccacc acttcttgaa gaaatggtgg cttgaaaaca atgacatcgc
     4441 gtctgcacac agaaccacgc ctgttttgtt acaaacagaa acatacagtt acagtcttca
     4501 tcgtcacaaa attctggcgt taggaaattt cagctacttc ctcggacttt atcagcttaa
     4561 tccatagact taatctcaag tgacattaac tcagatttta gcttttttaa atttgacata
     4621 gagataaatg taaagtcaag tcttccatct agagtagtga gaactatata agggttctgg
     4681 ggattgatta acctactcag ccccttacta gatagtttca aatctcgatt taacaaaagt
     4741 atcttggcaa tgactttgct tcttgctgcc ccttgccaaa gtcctccaac aaatggtgct
     4801 agataaaaag cgatcgtcgc cagtaaaatc aagataacta tgatgatact tattatctta
     4861 tccatttgta tttcctcttc cttttgcaca aatagactaa tttgaaatcg atctttgact
     4921 aagacaagaa aaagtgagca ctaccaaggt gttagttata ttgaacagtt gcgataggag
     4981 ctaaccgtct ttgtccaata ttaggctggg tgaatgtaat tagtgctgag acacaaggat
     5041 aatcctattg cagcgcctgc aacagttgta aatggattta atccagctgc ccctgctacc
     5101 gctcccccga tcgtggacac aatacaccca ctaggtttat tgcgtcgctt ggctcctcct
     5161 tggattaaga ccaaatcatg ctgttttaaa gtaatgccca cttctttact tatcattgca
     5221 tcccatctcc taagcattta atagctgacc caaccgctcc taagtttcca ccaactacgg
     5281 cgccgccgat tatcccaaaa ggaccaccag ctaggccagt aatcgttcct gatccaatac
     5341 ctgccgtgat gccagtaaca aatgtagcag cacaatcaaa tttctttttc ccacctgaaa
     5401 cccctgacaa ctgaaaatcg tcgagctggc gataattata agacataatt ttcctttttt
     5461 cttcaaaagg caacaagtta ttttgtgtaa ggtcgacttt actgtcttta acatacatta
     5521 attatttgtg taaaatgcca aaatttttta aacgtaggaa atttccagtt taacgtcgtc
     5581 tttacacttt tattgttcag ttgcgcttta aaagtcaaaa attcttaacg tttaaatctc
     5641 cttgcttggt aaaaacttca attttttgca aaaaaaatcg tctcagcaat ttgagacaat
     5701 tttttcatat catcaactta cggcaaatca ttccccgccg caaagtaaat gtcataccat
     5761 tcttgtcggg tcaacgtgct gtccgcgcct tccgcacttt ccttgatatg ttcaggattc
     5821 atagagccga gaatcacctg cacaccaact ggatggcgta atagccaagc gactgcgatt
     5881 gcatttttat tggtgtggta gtggtcagcg actttctgca gttcatcatt caacgcctta
     5941 aacttcgggc tatcgataaa ggtgccttca aacatgccgt attggaatgg tgaccatgct
     6001 tgtaaggtca tgtgtttgcg ttgtaagtat ggtaataggc tgccatcatg atcgaccgag
     6061 gcagcgtcgg ccatgttggt gtgcatcccc gcattgacca tgccagtatg ggcaacggag
     6121 aattgaactt ggtcaatcag caaaggctgc cgaatgccgc tttcaagcaa cgcaatttgt
     6181 tcagggttaa agttggagac gccaaaatgc cgaaccttgc cactttgttc caatgcatca
     6241 aaggccgccg caacgtcatc gacttccatt aacggatctg gccgatgcag caagaccgaa
     6301 tcaaggtaat caacctgcaa ccgtttcaaa atgtgatcaa ccgctgacag taagtgatct
     6361 tttgaaaagt cgtaccgttt gccgaatacc aaactgccat gagagcgttt tggatcaacg
     6421 acgatcccga ctttcgattg aatgaataac tgatcgcggg aaacgctggc ttgcttcaag
     6481 gcttcaccaa aaacttcttc ggatttgcct tggccataaa tgtcggccga gtcgataaag
     6541 ttgatgccgt cattgtacgc actatccagc acattggccg ctttgtcggg ggccagcaca
     6601 ttcatccgca tgatgcccaa ggccacactt gacgcctgcc aattggatcc gcctaatcga
     6661 acttgtttca taaacacaaa actcccttcg atacgtcatt tcaaattatg ttactgacga
     6721 caagttaagt gtagccccta aagtccactt gaggtcaagc caatattaga atttcaataa
     6781 aacagcttgc atggtgctga gctgcgcggt aggttaaact gtgtttgtta cttatttttt
     6841 cttagcagga taagcccata aaggaggccg tgattttgac agttaaagat aaagtggttg
     6901 taatcacagg tgcatcgagc gggattggcg cggcaacggt acaagtgttg gccgaggctg
     6961 gtgcaaaact agtcatcggt gcgcggcgca cagaacggtt ggctgaattg gcggccagct
     7021 ttacggacgg tcaggtgctg tatcaacaaa ccgatgtgac cgaccagcag caagtgaaag
     7081 cgctgattga tttggcgttg gataagtttg gtcatgtgga tgttttgtat aacaacgctg
     7141 gcctgatgcc actttctgaa atggccgaac tcaaagtcaa cgaatgggag cggatgattg
     7201 acgtcaacat taaaggcgtc ttgtatggga tcgccgcggt tttaccgcct atgattgccc
     7261 aacacagtgg ccaaattatc acaacagact cggtcgccgg tcacattgtt caccctggaa
     7321 ccgccgttta ctctggtacc aagtgggcta tccaggcgat catggacggc ctgcgacaag
     7381 aacaagcggc taatcatatt aaaacgacca tgatctcgcc cggtgccgtg aatactgagc
     7441 ttttcagcac aattaccgat cctaagcgcc gtgaagctgt tgaagccgat gaaaaaaaca
     7501 atggcctcag cgcctcggat gttgccaagg cagttttgta tgccattgat caaccggcca
     7561 atgttgccat caatgaagtg ctcttacggc cagtcacgca agaacgttaa ttttcgtcta
     7621 aaggagtgtg attgcatgtc gggttatcat tttttaaaac cgttcacctt caagcaccaa
     7681 accatcacgt tgaaaaatcg cattgtcatt ccgccgatga caacgcgcct gtcgtttgaa
     7741 gacggcactg tgacgcggga cgaaatcagg tattaccagc aacgggccgg tggcgtcggc
     7801 atgtttatta ccggtaccgc caatgtcaat gcgcttggca aaggattcga aggtgagcta
     7861 agtgtcgctg atgatcgatt catccccggt ttgagcaaac tcgccgctgc gatgaaaaca
     7921 ggcggcacca aggctatttt gcaaatcttc agtgctggcc gcatgagcaa tagcaagatt
     7981 ctgcgcggtg agcagccagt cagtgccagt gcggttgctg cgccacgggc gggttacgaa
     8041 acaccgcgcg cattgacacc ggcagaaatt gaggccacta ttcacgattt tggtcaggcc
     8101 gtgcgccgcg ccatccttgc tggttttgat ggcatcgaac tgcatggtgc caacacatat
     8161 ctgatacagc aattctattc gccaaactct aatcgccgaa ccgatgaatg gggcggtgac
     8221 cgcgataagc ggatgcgttt tccgttggca gtcgttcatg aagcagaaaa aatgattgcc
     8281 acaattgctg accggccatt tttgttaggc taccgcattt cgccggaaga gttggaacag
     8341 cctggcatta ccttggatga taccttggcc ttaatcgccg ctttgaaaca aaccaagatt
     8401 gattacctgc acgtctccca aagtgacgtt tggcgaacct cattgcgcaa ccccgaggac
     8461 acagccatca tgaatgaaca aattcgtaac cacgtcgccg gtgcttttcc agtgattgtg
     8521 gtcggtggca ttaaaacccc cgccgatgct gagaaagcgg cagaatcctt tgatttggtc
     8581 gcgattggtc acgaaatgat tcgcgagccg cactgggttc agaaggtctt agaccatgac
     8641 gaaaaggcga tccgtttcca gatcgcccct gctgatcttg aagaacttgg cattgcgccg
     8701 accttccttg attttatcga aagtatttcc ggtggggcaa aaggtgtccc gttaacaact
     8761 gcgcagtctg tgacatcaag caacgtgact caagattaat ctagcatttc aaatcatcgt
     8821 gcgagtcgag ctgtaaaaag ctcgcctttt ttcttgccgt cttcaactta cgcgatggtg
     8881 cctgaagcta ccagtgattt ataagtttta aatcaaggtg tgatcatcac ctgctcacgc
     8941 tctgatttaa acgcgttcac cagcgcagct cggctatgcg aagaacagtg acacagatgg
     9001 tccaaagccc agaccatctg tgtcactgcc acttcgctac gccgagctaa ccgcgccagt
     9061 tcacgctctt gtcattttta acgggtcgac ccatttatca aactgcgctg ctgtgacgtc
     9121 gccgcttttg atggcggctg cttttagatc gaggttttct tgctcagcca attgcgcgat
     9181 ggcggcactt ttttcgtagc cgatgtgggg tgcgagggcg gtgaccagca tgagcgaatg
     9241 atcaacgagt gctctcatat gcggtgcgtg gatggtcaag ccggcagcta atttttcagt
     9301 gaaactcgtg actgttttgg ttagtagatc agctgactct aaaaaggtac tgatgataac
     9361 cggcttgtag acgttcaatt caaaattgcc ttgtgaagcg gccaccgtga tcgtcgtatc
     9421 gttgcccatg actcgaacag cggccatggt tagcgcttcg gcctgtgtgg gattcacttt
     9481 gcccggcatg atggaactac caggctcatt ggccggaatg cgcaactcgc cgtatccagc
     9541 acgtggacca ctggcaagga agcgaatgtc attggcgatt ttaagcagat cagccgctag
     9601 cgttttaatg gcaccatgaa caacgctaat ttctgagtga gccgctaaag cagcaaactt
     9661 attggttttc gccgaaagtg gtaattgata aacatcgctc aatcggcccg ccacaatctt
     9721 gccaaagtta gggtcagcgt taagccccgt tccgactgct gttccgccaa tggctaagta
     9781 aaaaagattg ggctgaagcc gctttaaagc aatctgatca tgttccatca tggccaccca
     9841 tccgctgatt tcttggccaa acgttagcgg cgttgcatcc tgtaaatgag ttcgaccgat
     9901 tttaacaaca cgagcgtaag tgacggcttt tgaatataaa acactgcaca gttggttgac
     9961 agcgtgcagc aactgattca ctgcaatagc cgacgtaata ttcatcacag ttggaaaagt
    10021 atcattggag ctttgactgt gattcacatc atcattcggt aagatcggca agtcggggtt
    10081 gagttttgca gcttggtggc taatgacttc gttcacattc atatttgttt gtgtgccaga
    10141 cccggtttga tagacatgca gtggaaaatc tttttgcagt ttttcgtctg gcaaggccaa
    10201 caaggcatcg actgctcgcg tgattaattg gccttttggt gccggtaaaa catcagcggc
    10261 cacatttgct cgcgctgccg cttttttgag ttgcagcaag gccctaatca ctggcatcgg
    10321 catcaatgga ccagcctgaa aattatggcg gctgcgctct gtttgcggtc cccacaaagc
    10381 gtttgccgga atttcaactg gtcctaatgt gtccgtttct gttcgatatt tgctcatgtt
    10441 tacctccgtc atcaccatca gaaaaattca accaacatgc ctatttgcat agacctattt
    10501 tacacgaatt cgcccacg
//
