LOCUS       c00020_gnlPro..        15891 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJFPAJLA_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 21:44:46
            Original ID  :: gnl|Prokka|CJFPAJLA_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15891
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15891
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3356:5891]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3357..5891
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..15891
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15891
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(33..2306)
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MSDKFHGLTQAEADKRLKEDGLNEVPEPEYNFFKEFLSKLWNLSA
                     WILEAALILECILGKWVQSLFVLLMLLFAAFNGASKKKQSRRVLNNISHKLTPTVSVER
                     DGKWIKLDSKQLVKGDLISLKRGDVLAADVKIVDGNLACDESSITGESKPVKKAIDDTA
                     FAGTTVVEGDGLAVVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFNTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTS
                     DLTGIQDAANLNLLLLDKTGTITENKTAVAAWTDLSDLPDKDVLALAGAATDKRNAGII
                     DTAIDEYLVENNIPVMNAENFTPFTSDTGYSMADVAGHNVKLGSFKQLSLIDKHADEEI
                     SGINFKAGRSVAVLIDDKLAGVFILQDKVRTDSKAALAELKKRGVRPIMLTGDNQKTAA
                     AVAEQVDLTGEVISIHDFNENTDINDLAGIADVLPEDKLKMVKLFQEKGYIVGMTGDGV
                     NDAPALKQAEVGIAVSNAANVAKRSGKMVLLDDGLGSIVKILDAGHRVYQRMTTWSLTK
                     LARTAELTMLLTFGYLFFDYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     KLAKIAFSLAAGCTLIGIGFVWFLNTHGWSHGAVSTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGSVQIADVLLTFILALCGWAMVQISIQNLAITVIVAIIAAIIIDLIYQPV
                     MKNR"
     CDS             2435..3283
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     75.6; E-value: 7.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="LysR_substrate (E-value: 8.2e-30,
                     bitscore: 94.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.8e-24, bitscore: 75.6,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLKQLRYFLVVAEEKQITAAAKRLYIAQPPLSYQLKQLEKELGA
                     QLFKRTAHGIELTDVGQIFQSYANEIISLAQNAENQVHKTISGELGTIAIGMASSSTGL
                     IPMNSFNELRKYYPEISFDIYEDNTYGILDKLEKKTIDLGIVRTPYNQTGLNTKTLTTE
                     KMMAISVDPDFQQKKELRIKDLADQPLIIYRRFEDIFNQTFAHHGLKPFYAVKCDDSRT
                     AITWAKRKMGVALVPESIATTYAQENMIAIKHANWITHLQLVWRKDHQVTPLMKKIIAA
                     I"
     CDS             3357..4586
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="Amidinotransf (E-value: 4.6e-109,
                     bitscore: 355.5, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPIHVYSEIGKLKTVMLHRPGKELENLAPDILHRMLIDDIPYL
                     KIAQEEHDAFAHVLRQQGIKVLYLEDLLAESLTDEKVRRAFLDQLLDESSIKKQDPLHQ
                     LLLNYLQELLTKEMVKTVIAGIRKSAIHNSTPSLADLAEDPDYPFYLDPMPNVYFTRDQ
                     QAAIGSGMTINRMTFRARRRESLFMETILKNHPDFKNATIPVWRDRYHHGRLEGGDELV
                     LNNHVLAVGISQRTSATAITDLAHNLFDHSSYDTILAIKIPHNHAMMHLDTVFTMINYN
                     QFTVHPFILDKAGKIDIYVLQPDDHNGVKITEKNDLVQVLKENLHLSELDLIPTGGGDP
                     IAAPREQWNDGSNTLAIAPGEVVTYDRNYVSNDLLRKHGIIVHEIRSSELSRGRGGPRC
                     MSCPLIREDL"
     CDS             4597..5028
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="OTCace_N (E-value: 1e-37, bitscore: 120.5,
                     seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSFLDCKDYTPAEISYLIDFALHLKELKKEHIPHE
                     YLKGKNIALLFEKASTRTRSAFVVACNDLGAHPEYLGASEIHLGKKESVKDTAKVLGSM
                     YDGIEYRGFAQEDVEELAKYSGVPVWKWVMAAIMLPTVF"
     CDS             4989..5891
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="OTCace (E-value: 4.2e-49, bitscore: 157.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="AA_kinase (E-value: 1.9e-20, bitscore:
                     64.4, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGDGRDNVADSLLVCGSMLGVNVHIVTPKPLFTHPDVQKIAQNFA
                     QDSGSKNLITDDIAQGVKGANVVYTDVWVSMGENDWSERIKLLKPYTVTMKMMQMTGTP
                     DDQLIFMHCLPAFHDRTTQVGEEIYEKYGLNEMEVTDEVFNSKYAWQFTEAENRLHSIK
                     AVMAATLGNLFIPIACGGGGILVIVKDGHLRGVAGVIDKDFSATKMAEDINADELVILT
                     TVDHAFLNYGKENQQAIGKIKVEQLKQYLAAGYFAAGSMKPKIEAAIEFVEKTGNLAII
                     TSLSNANKLADGVGTIIYN"
     CDS             5905..6441
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MNIFNEGKKQDIAQVLAAKDRRVAVQHKIFNKYPNQTLVDIKMNI
                     PGPIKNNRYLTKMFMLGINELENAWTNLGYHFKLVTQLNDDSGCENFYVLSLSIEKVKR
                     STIDFENQISLGRLFDADVLVKNKQAAISRRDLDRQPRKCFLCDRPAKECARSRRHSVE
                     QMQAFISQLYQEYVA"
     CDS             6557..7723
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MELKKNKNNLKQITALIQYAFLKNNDLTKDENFMSRYDHSTGYGY
                     FDKEKLASYIMVNRFKSDVFGHHLPMAGIGYVASYPEYRGQGHISQLMKEILHDLHRQD
                     IPFANLAPFSESFYRQYGFSNSIYQKEYRFDGSALRSFKLPRSGHIVRGKWDNLAVQNG
                     VIQLYERQLHTDDERNTVVREAWWWNRLDSYYHHRNVAVYFDADERPISYLIYRIRDNT
                     FLADEMYAITPQGLLSMFGFMGSHAGSVKQFKMSVPEKSLRAELFPEQNELQVDLRPYM
                     MSRIIDFEKVLACMRPMQEGDFNLEVNSDEQCPWNIGVWQLSNHGRKVAVERKEDALVD
                     FSGSITAWTQVLLGRLTMNAAVKLGLITDYRIKKLDFVKGDVSFYDYF"
     CDS             7739..7900
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MSKEKKLNLIKLFGIVVSGLNLIFFALMALNKHEDTKDKRRVAEE
                     GHAPLDEK"
     CDS             7890..8507
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_9"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-13,
                     bitscore: 41.3, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNKMTELKIAYFDQLGRKELDQAVQHFVLKHPNVDVKLLATSHD
                     GAFAKLNEDEADIAINDLRDENLNFDETELTQAGVMAILPKGMYPNGIQMIEKDELNDM
                     TCFIVAKPEEEVSELHLFKDLYQIGSQFIASNSVEEAALLVASGSGYFILNENTARLIN
                     TTDLQPLFLLDHGQLIKQKIMAFYKSNSALSSEFIKLLQQEY"
     CDS             8606..9145
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MLKRTLLPLTSMVLVLGLTGLASQVETVDASTYGNGVQVTIPKKM
                     QGTWYSYDRNAHNGTKITFTEHTVNGKPIFTQEASTISDYFNGRIANQKNFDKVTQNWM
                     SGKTTKMKNDTFYEIDPWITFENWSLYRVVPQTINGKKHNVLVYSSRYDGGNYFRSKKL
                     AKKMKDYKFKKVNYTL"
     CDS             9241..9903
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MKLKQTPILRLYKLETNKEDHAKFVKAGQHNMLTSQENEPGTLFM
                     QTSHDEETTNFVVECYQDEASYDTHANSKQFKDFTDVAKDILTSRVKVELFPEFISTKA
                     EKLAVTGSNDYVIYLTEIGVSLGKGDEFSHAVMKEMKTAVEEEKDILAMIAGTVADQPN
                     EWLAIEVYRNNEAYKQHLETKNFKEYLNNTKYCVESKSLRKSQPDVIVDQGAIFYQP"
     CDS             10473..11492
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MPGIVEQTLLEQQNIDLNEMVTMNQMIDQLLPNASKELQQKLKIK
                     IYNFVRTRKQPSITVRRRKYFKPAVAKLIIGNVQDYADAIERRAKEAPAKEDATDKKPA
                     SKSKRVKTITKRKILAKVIKNDKIDKSIQKKLEDKIASIVKTNFIKPVNKRGSFSVEDG
                     EKVIAELSPFYQNIKIDQKYRKNAEKAAENKETETKEKPEQHSKDQNESREGQSKDFER
                     KNNQKNSNNRNNNQTQNQRKRQNKHPFEIRRENNNRSRNNQSNRRYNNRNNYEFDEASG
                     LRERYNTVIRNYNQLEQRYNALQDKYNQALDDKARLIEEMGKKNEDLRRVLIDVLRKM"
     CDS             11666..13264
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="MSLKELFKSNVFRACIIILLYVLYALFGSFSEYLFKYALNSITAG
                     NFNTYVYWQIMQFVLALFTSLLLPITTVVFTRQTQNYLHKIRQEIMHHYYDEKSDEKVS
                     SMQNRLTANLKILSDDYATPWITILSGVLEIVIAIILLASMNWILILVTAILAVITLFA
                     PKIMEKKTSAATDKVNKKNEKLLNTIAHWLGGLQELRRYSAYSRLVKQIHRSSSDYVDA
                     SKGSAKLRSVSYLINAFSNSIAQIGMSFIAGIMFLLNMISFGDFAVASGFAFTIFSAIW
                     NITQSLTQVKSTKALREQITDLRKQVPDENKDKVSAYGLKVSGLSVKYDQGETIFYPDF
                     TIKKGQKVLLTGDSGTGKSTLFNVLLGKLKPESGTVTYLDENETIIPEGKARIGNMPQN
                     PVVFPATIKENITMFNENLQDKLQDVVQAVQLQSDLAKMPDGVNTTIDLKSENLSGGQR
                     QKVVLARTEIHEQSFVLMDEVTSAIDQKATEKIIDELLKTDQTILMIAHNFTPELKAKF
                     DQEIKLKSKKGDKVR"
     CDS             13261..14844
                     /locus_tag="ctg20_14"
                     /transl_table=11
                     /translation="MNLKAFIKTNPVRFWLTAIGWIIIPALSITNTYVVQEETNILLSR
                     NWTKFILINVLAFLIMLVDYGVSALVDYQQQAQVQDLNDQVRDKIVKRYYYDGKKHTVA
                     QMQNRLTNDLQMLNNNYFINVFLLIYGVSTIVFVLIYLILLSWQLLLAICLMVAISLLL
                     PKLTEKPLQKATELISDSNQKYLDTLNDWLSGLDQLQQFLAGAKLFSVIEKTSKKLEDA
                     NVKQTAYIKLLNAVNGIVSAAFGLALFVLAGWLVKNHQIPIGALLVVGNFRYYLNGGID
                     TLTNGLGAMKGSKKLLAEVDKSASDIPMQAEKDVVMPNVIKTKDLVLKFPNGEKLTYPD
                     LEIKQGEKILLTGDSGAGKSTLFKLILGELKPSAGKVVYEDKAGKKINPDLSKIGYLPQ
                     DPVVFPASIEENITMFNEKLNGKVKQVINEVNFADDIAKFTEGLDEKINLDKLNISGGQ
                     RQKIVLARAKVHNSDIILIDEGTSAIDQKATMLILKNLLKSKTTIVFIAHNFNEGMHQL
                     FDREIHLVKE"
     CDS             complement(14888..15607)
                     /locus_tag="ctg20_15"
                     /transl_table=11
                     /translation="MTTKIEKISPKIYKVTDNDKHLGTISTYHNLFHNKYIYLKFNLSD
                     YSVNIPFSKIVQAEHQALQVMIDSNENPIVDFLLRNGFICKRHCYTLTVNKKDLKIEIN
                     NKLSLHFFNTESPDYRTCCQLLYKYYKQVHQSVSPLTANIDTFIQEVPTKTGYYSTNEL
                     GEIDNLVFTENNEIAYICSWDRFSSNNFIETILVKMFQNYPSIFFEADDTDWMAYQLLS
                     YFKINKNNSFNTYIFPN"
ORIGIN
        1 cttttaattt ataaaatttt tatggtaata atctatctgt ttttcatcac aggttggtaa
       61 attaagtcga ttattatggc agcaataatc gctacaatta cggtgattgc tagattttga
      121 atagaaattt ggaccattgc ccaaccacaa agagctaaga taaaggtcaa tagaacatct
      181 gcaatttgaa cactaccaac caacttggat gggtaatctt gccaaaagta cttacgagtt
      241 ctagtaatca aaacaatcaa cattgcgcta agaactaggt atacgtaaac catagtagaa
      301 acagcaccgt gactccaacc gtgtgtgttt aagaaccaaa caaacccaat accaattaga
      361 gtacaaccag cagctagtga aaaggcgatc ttagcaagct tagccatatt ccagttttct
      421 ggcttataag taatgtgagt ccggtcggtc ccaatcatca tcgtaaccat attgttcata
      481 atggtataga taaccattgc attcaaggcc attgggatgt agtcaaagaa aagatagcca
      541 aaagttaaca gcatcgttaa ttcagcagtt ctagcaagct tggttagtga ccaagtagtc
      601 attctttggt atacgcgatg tccagcgtct aaaattttaa caattgagcc tagaccatcg
      661 tctagtaata ccattttacc cgaacgctta gctacgttag cggcatttga aaccgcgatt
      721 cctacttcag cttgttttaa tgcaggtgcg tcgttaactc cgtcaccagt catccctacg
      781 atatagcctt tttcttggaa aagctttacc atcttgagtt tatcttctgg taaaacatca
      841 gcaataccgg ccaaatcatt aatatcagta ttttcattga aatcgtgaat cgaaattact
      901 tcaccagtta aatcaacttg ttctgccact gcagcagcgg tcttttgatt gtcaccagtt
      961 aacataattg ggcgaacgcc acgtttcttg agttcagcca aagctgcttt agagtctgtt
     1021 ctaactttat cttgtaagat gaagacacca gctaacttat cgtcaatcaa gactgccact
     1081 gagcgtcctg ccttgaaatt aattccagaa atttcttcat cggcatgttt atcgatcaag
     1141 gataattgct taaatgaacc aagctttaca ttatgtccag caacatcagc catagaataa
     1201 ccagtgtcag aagtaaatgg agtaaagttt tcagcattca tgactggaat gttattttct
     1261 actaagtatt catcgattgc tgtatcgata ataccagcat tacgtttatc agttgcggct
     1321 ccagctaaag caagcacgtc tttatcaggc aagtcactta gatcagtcca agcggctacg
     1381 gcagttttgt tttccgtaat tgttccagtc ttatcaagta aaagcaagtt caagttagct
     1441 gcgtcctgaa ttccagttag gtcagaagtc aggactcctt ctttacttaa gcgggttgct
     1501 tcaaatgagt tggataaagc aaaagttgat ggcattgcta caggaattga agcaataaac
     1561 atcattgcca ggaatggcaa catattaata aaggtattga aattaccgcc tttgaagaag
     1621 gaggcgataa taataactaa ggttaaaaca ccatctagta agcaaaggta gtagataatc
     1681 ttagtcaaaa gttgttgtaa gtgaccagga gcagcggaat tgttgatcaa attaatcgtc
     1741 ttaccgcttc tagaatcttt acctgtagca gtaacaacag ctaggccatc accttcaaca
     1801 actgtagtac cggcaaaggc ggtgtcatca attgctttct taactggttt agattcacct
     1861 gtaattgagc tttcatcaca agctaagtta ccgtcaacaa ttttaacatc tgctgcgagt
     1921 acgtccccgc gtttaagtga gattaaatcg cctttaacta gttgtttaga atcaagtttg
     1981 atccacttgc catcgcgttc aactgataca gtaggagtca acttgtgtga aatattattt
     2041 aaaactcgtc ttgattgctt tttcttagat gcaccgttaa atgcagcaaa taaaagcatc
     2101 aacaacacga ataatgattg gacccatttg cccaagatac attctagaat taaagcagct
     2161 tctagaatcc aagcggatag gttccataac ttagacaaga actctttaaa gaaattgtat
     2221 tcaggctctg gtacttcatt taagccatct tcttttaagc gcttgtctgc ttcggcttga
     2281 gttaagccgt gaaatttatc agacattatt ttccctccaa atctacctta ataaggtagc
     2341 acagatattg ctatgaataa aatactaaaa tacaatataa gatattaaat attttaatat
     2401 cactatcaat tgaaataaaa aaaggataaa taatatgaat ctaaaacagt tacgttattt
     2461 tctagttgta gcagaagaaa agcagattac agcagctgct aagcgcttgt atattgcaca
     2521 gccaccatta agctatcaat taaaacaatt agagaaagag ttgggcgcgc aattatttaa
     2581 aagaacggca catggtattg agctaactga tgtgggacaa atttttcaaa gctatgccaa
     2641 tgaaattatt tctctagctc aaaatgctga aaaccaagta cataagacta tttccggtga
     2701 attgggaacg attgcaattg gaatggcatc ttcctcaacg ggcttgatac caatgaattc
     2761 ttttaatgaa ttacgaaaat attatccgga aatttctttt gatatttatg aagataatac
     2821 ttatggcatc ctggataaat tagaaaaaaa gacaatcgat ctaggcattg tacgaacgcc
     2881 ttacaaccag acaggtttaa atactaagac tttaacaact gaaaaaatga tggctattag
     2941 tgtagaccca gattttcagc aaaaaaaaga attacgcatt aaagatctag cagatcagcc
     3001 attgattatt tatcgccgct ttgaggatat ttttaatcaa acttttgcac atcatgggct
     3061 taagccattt tatgcggtta agtgtgatga ttcacggaca gcaattactt gggccaagag
     3121 aaaaatggga gtagcgctag taccagaatc aattgcgaca acttatgccc aagaaaatat
     3181 gatcgcaatt aaacatgcta attggataac acatttgcag ctggtttggc gtaaagatca
     3241 tcaagttaca cctttaatga aaaaaatcat tgctgcaata tgataatact gtaacttttg
     3301 cctaattgat ccataataaa tgtaaacggg tacaataatt aatagaaggt ggttgaatgt
     3361 cgagtccgat tcatgtttat tcagaaattg gtaagttaaa aacggtgatg ttacatcgac
     3421 cgggaaaaga actagaaaat ctagccccag atattttgca tcgaatgttg attgacgata
     3481 ttccttatct gaagattgcc caagaagaac atgatgcttt tgcgcatgta ttgaggcagc
     3541 aggggatcaa agtattatat cttgaggatt tattagcaga atctttaaca gatgagaaag
     3601 ttcgtcgggc attcttagat cagttactgg atgaatcaag tattaaaaaa caggatcctt
     3661 tgcatcaatt attgctgaac tatctccaag aattgctaac taaggaaatg gtaaaaacgg
     3721 tgattgctgg aattagaaaa agtgcgattc ataattctac cccatcttta gcagatttgg
     3781 ctgaggaccc agattaccct ttttatcttg atccaatgcc aaatgtatat tttactcgag
     3841 atcaacaggc tgcaattggt tcagggatga ccattaaccg gatgactttc agagctagac
     3901 gacgtgaatc attatttatg gaaacaattt tgaaaaatca tcctgatttc aagaacgcaa
     3961 ctattccagt ttggcgtgac cgttatcatc atggtcgcct tgagggcggg gatgaactag
     4021 ttctaaataa ccatgtgtta gctgtaggta tttcacaacg cacttctgca actgcaatta
     4081 ctgacttagc tcataattta tttgatcatt caagttatga tacgatttta gcgattaaga
     4141 ttccgcacaa tcatgctatg atgcaccttg atacagtttt tacaatgatt aattataatc
     4201 aatttacggt tcatcccttt attttagata aagccggcaa aattgatatt tatgttctac
     4261 agcccgatga tcacaacggt gtaaaaatca cagaaaagaa tgatttggtg caggttttga
     4321 aagaaaactt acatttaagc gaattggatt taattccaac tggcggtggt gatccaattg
     4381 ccgcaccacg tgagcaatgg aatgacggct caaatacctt ggcaattgca ccaggtgaag
     4441 tcgttactta tgatcgtaat tatgtatcca atgatttgct aagaaaacat ggcatcatcg
     4501 ttcatgagat tcggtctagt gaactctcac gtggtcgtgg cggtcctaga tgtatgtcgt
     4561 gtccgttgat tcgtgaagat ttataagagg caaaaaatga aatatttaca aaatgttttt
     4621 caaggtagaa gttttctcga ttgtaaagac tatactccag ctgaaatttc atatttaatt
     4681 gattttgcat tacatttaaa agaacttaaa aaagagcata tcccacatga atatctgaaa
     4741 ggtaaaaata ttgcactact ttttgaaaaa gcctcaacta ggacgcgatc tgcttttgta
     4801 gtagcttgta atgatttagg tgctcatcca gaatatctag gcgcaagcga gatccactta
     4861 ggtaaaaaag aaagcgtcaa ggatacggct aaagtcctag gctcaatgta tgatggaatt
     4921 gaatatcgcg gttttgctca agaagatgta gaagagctgg ctaaatattc tggcgttcct
     4981 gtttggaagt gggtgatggc cgcgataatg ttgccgacag tcttttagtt tgtggctcaa
     5041 tgttaggtgt taatgtacat attgttacac ccaagccttt gtttacacat cctgatgtac
     5101 aaaaaattgc tcaaaatttt gcccaagatt caggttcaaa aaatttgatc acagatgata
     5161 ttgctcaggg cgttaaagga gccaatgttg tttataccga tgtttgggtt tcgatgggtg
     5221 aaaatgattg gtctgaacga attaaattat taaagccata tacggtcaca atgaaaatga
     5281 tgcaaatgac tggtacacca gatgaccaat tgatctttat gcattgtttg ccagcttttc
     5341 atgatcgaac aactcaggtg ggagaagaaa tctatgaaaa atatggctta aatgagatgg
     5401 aagtaactga tgaggtcttt aattcaaagt atgcttggca atttacagaa gctgaaaatc
     5461 gattgcattc aattaaagca gtgatggcgg ctactttagg aaatttattt attccgattg
     5521 cctgtggcgg tggtggcatc cttgttattg tgaaagatgg gcatctcaga ggtgttgccg
     5581 gcgtaattga taaagatttt tccgctacta aaatggcaga agatatcaac gctgatgaat
     5641 tagtaattct aacaacggtg gatcatgcat ttttgaatta tggcaaagaa aatcaacaag
     5701 caattggtaa aataaaagtt gaacagctca aacaatatct agcagcaggt tatttcgcag
     5761 ctgggagtat gaagcctaag atagaagctg caattgaatt tgtagaaaaa acaggtaatt
     5821 tagcaattat cacctctttg agcaatgcca acaaactagc agacggagtc ggcacaatca
     5881 tttataatta actgggtgat aaaaatgaat atttttaatg aaggaaaaaa gcaggatatt
     5941 gcccaagttt tagcagctaa agataggcga gtagctgtac aacataagat ttttaataag
     6001 tatcctaatc aaactctagt cgacattaag atgaatatcc caggaccaat caagaataat
     6061 cgctatttaa ctaaaatgtt tatgttgggt atcaatgagc tggaaaatgc ttggactaac
     6121 ctaggttatc attttaaatt ggtgacacag cttaatgatg atagtggctg tgaaaacttt
     6181 tatgtattat ctttgtcaat tgaaaaagta aagcgctcaa caattgattt tgagaatcag
     6241 atatcattgg gacgtctctt tgatgcagac gtgttggtaa aaaataaaca agctgcaatt
     6301 tcacgcagag atttggacag gcagccacgt aagtgctttt tatgtgatcg ccctgctaaa
     6361 gaatgtgctc gcagccggag acattcagtg gaacagatgc aggcatttat ctctcagctt
     6421 tatcaagaat acgttgcgta aaataaaccg ggattttatg attccggttt atttttatga
     6481 aaaatctagt taaaaattta aaaaatgaac taaaatagta atgaataaat ttatagatgt
     6541 acgtatagga ataagcatgg aattaaagaa aaataagaat aatttaaagc aaattacggc
     6601 attaattcaa tatgcatttt tgaaaaataa tgatttgact aaagacgaaa attttatgag
     6661 tcgttatgat catagtacag gttatggcta ttttgataag gaaaaattag ctagctatat
     6721 tatggttaat cgatttaaaa gtgatgtttt tgggcatcat ttaccgatgg ctggaatagg
     6781 ttatgtagct tcatatcctg agtatcgtgg ccaaggtcat atttcccaat taatgaaaga
     6841 aattttgcat gacttacata ggcaagatat tccttttgct aacctggcac cattttcgga
     6901 gagcttttat cgccagtacg gatttagcaa tagtatttat caaaaagaat atcgctttga
     6961 tggaagcgca ttgcgtagtt ttaaattacc acgttctggt catatagtgc gtggcaagtg
     7021 ggacaattta gctgttcaaa atggtgtgat tcaactttat gaacgtcaac tgcatactga
     7081 tgatgaacgt aacacggttg tacgtgaggc atggtggtgg aatagacttg attcttatta
     7141 tcatcaccgc aatgtagccg tttattttga cgcggatgag cggccaatta gttacttgat
     7201 ttatcgcatt agagacaata cttttttagc tgatgaaatg tacgcaatta cgccgcaggg
     7261 attactgagt atgtttggtt ttatgggttc gcacgcgggc agtgttaagc aatttaaaat
     7321 gagcgtacca gagaaatcgt tacgagctga actttttcct gaacaaaacg aactccaagt
     7381 tgatttgcgt ccttatatga tgagtcgaat tattgatttt gaaaaagttt tggcttgtat
     7441 gcggccaatg caagaaggtg attttaatct ggaagtcaat agcgatgaac agtgtccttg
     7501 gaatattgga gtttggcaat taagtaatca tggacgtaag gtagcggtag aacgtaagga
     7561 agatgcattg gttgattttt cgggatcaat taccgcgtgg acccaggtgc tattaggtag
     7621 actaaccatg aatgctgctg ttaaactagg attaattaca gattaccgca tcaaaaaatt
     7681 agattttgtt aaaggcgatg tatcatttta tgattatttt tagttgtgag gttaaaaaat
     7741 gagtaaagaa aagaaactca atttaataaa attatttggc attgtagtta gtggtttgaa
     7801 tttgatcttt tttgccttga tggcacttaa taagcatgaa gatactaagg ataaaagaag
     7861 agtagcagaa gaaggacacg caccgctgga tgaaaaataa aatgacggaa ttaaagattg
     7921 catattttga ccaattaggt cgtaaggaat tagatcaggc agtgcagcat tttgtgttaa
     7981 aacatcctaa tgtagatgta aaactacttg cgactagtca tgatggtgct tttgcaaaac
     8041 tgaatgaaga tgaagcagac atagcaatca atgatttgcg tgacgagaat cttaactttg
     8101 atgaaacaga attgactcaa gctggtgtaa tggcaatttt gcccaaggga atgtatccta
     8161 atggcattca aatgattgaa aaagacgagc tcaatgatat gacttgtttt attgtggcta
     8221 aacctgaaga agaggttagt gagctacatt tatttaaaga tttgtatcaa attggcagtc
     8281 aattcatcgc ttctaactcg gtcgaagaag cagcactgtt ggtcgcctct gggtctggct
     8341 attttatttt aaatgagaat acggctaggt taattaatac tacagatttg cagccacttt
     8401 tcttgcttga tcatggtcag ttaataaagc aaaagataat ggctttttat aagtcaaatt
     8461 cagcgttaag tagtgagttt ataaagctat tgcagcaaga atattaatct gtaaagttaa
     8521 aaatatcttg tctaagtact ataagatact gtaaaatata ttatgaaagc ggattcatat
     8581 attttacatt ctggagatga tttttatgct aaaaagaact ttgttacctt taacatcaat
     8641 ggtacttgtt ttaggattaa ctggtttggc tagtcaagtt gagactgttg atgcttcaac
     8701 ttatggtaat ggtgtacagg ttactattcc aaaaaagatg cagggtactt ggtactctta
     8761 tgatcgtaat gcacataatg gcacaaagat cacctttact gaacatactg ttaatggcaa
     8821 accaatattt acccaggagg cttcgacaat tagtgattac ttcaatggta gaattgctaa
     8881 ccagaagaac tttgataagg taacgcaaaa ctggatgtct ggtaaaacta ccaaaatgaa
     8941 gaatgataca ttctatgaga ttgatccgtg gattactttt gaaaattgga gtctttatcg
     9001 agtggtacca caaaccatta atggtaaaaa gcataacgtg ctggtttatt ctagtagata
     9061 tgatggtggt aactacttca gaagcaagaa attagctaaa aaaatgaagg actacaagtt
     9121 taagaaagtt aattacacgt tatagttttg taacatccct taactaaggg atgtttttta
     9181 ctaatagacg cgataaaatt tagtataata atgacaaaat taattcttgg aggagaagtt
     9241 atgaaattaa aacaaacacc aattttgcgt ttatataaac tagaaactaa taaagaggat
     9301 catgcaaagt tcgttaaggc agggcaacat aatatgctta cttctcaaga aaacgaacca
     9361 ggcacattgt ttatgcagac aagtcatgac gaagaaacta ctaattttgt agtagaatgc
     9421 tatcaagacg aagcaagtta tgatactcat gctaattcaa agcaatttaa ggattttact
     9481 gacgttgcta aagatatttt aactagtcga gtaaaggtag aattgtttcc ggaatttatt
     9541 tctacaaagg cagaaaaact agcagttacc ggatcaaatg attatgttat ttatctgact
     9601 gaaattggtg tttctttagg taagggcgat gagttttctc atgctgtaat gaaagaaatg
     9661 aaaacggcag tcgaagaaga aaaagatatt ttggcaatga ttgcaggaac tgttgccgat
     9721 caaccaaatg aatggttagc tattgaagtt tatcgtaata atgaagctta caagcagcac
     9781 ttggaaacta agaacttcaa agagtatttg aataatacaa aatattgtgt tgaaagtaag
     9841 agtttacgta agtcgcaacc agatgtaatt gttgaccaag gtgcaatttt ctaccaacca
     9901 taaagaataa gacgaaaaga agaccaggct atgtggagta cataacctgg tctttctagt
     9961 tagaggggaa aagatttatt aacatatatt attctggttt ttagtggcga tgttttacct
    10021 ttgctactgc tggtttatta attaatactg agctgatggc cattaaacca agcgttaaaa
    10081 atgatccacc aattaagagt agtttaatca aggttctcat tcctttcatc ttaattgatc
    10141 ttataatagc gaaataatat taagaattta tatgtaaaac ctaatggatt agttaagaaa
    10201 ataaaactag aaaaaaggct ggttagcacg taaaatagaa atagagtcaa agtctagtgc
    10261 aactgcgcat aaaataaagc agtatcgatg ggatgctgct tgttttggtt aaaaaataga
    10321 gaatatgctt gtagcccttt tcgtaaatag cgttaatgtt gtaaaatgga aagtgcatta
    10381 agtttattaa tgagaaaatt gatgtattat tgcaaaatag gccgtaatgg ccctttttgt
    10441 tgtgaaaaaa ttaaaagaat ataggattgg aaatgccagg aatagtagag caaacattat
    10501 tagaacaaca aaatattgat ttaaatgaaa tggtaacaat gaatcaaatg attgatcaat
    10561 tgttgcctaa tgcaagtaaa gaattacaac aaaaactaaa gattaaaatt tataactttg
    10621 tgcgtacacg taaacaacca agtattactg tgcgaagaag aaaatatttt aagccggctg
    10681 ttgctaaatt aattattggt aatgtacaag attacgcaga tgcaattgaa cgtcgtgcta
    10741 aggaagcccc agctaaagag gatgctactg ataagaagcc agcttctaaa tctaagcggg
    10801 ttaagacaat tactaagcgt aagattttag ctaaagttat aaagaatgat aagattgata
    10861 aatctattca aaagaaatta gaagataaga ttgcttcaat tgtgaagacc aactttatta
    10921 agccagttaa caagcgggga agtttttcgg ttgaagatgg tgaaaaagtt atagctgaac
    10981 ttagtccttt ttatcaaaat atcaagattg atcaaaagta tcgcaagaat gctgaaaaag
    11041 cggctgaaaa taaggaaaca gaaactaaag aaaagcctga gcaacattct aaggatcaga
    11101 atgaaagtcg tgaaggtcaa tctaaggact ttgagcgtaa gaataatcag aagaatagca
    11161 ataatcgaaa taataatcaa acgcaaaatc aacgtaagcg acaaaataag catccttttg
    11221 agatcagaag agaaaataat aaccgctcac gtaataatca gtctaaccgc cgctataata
    11281 atcgaaataa ttatgaattt gatgaagcta gcggtttgcg tgaacgctac aatacagtaa
    11341 tcagaaatta caatcaactg gagcaaagat ataatgcttt gcaagataaa tataatcagg
    11401 ctttagatga taaagctaga ttgatcgaag aaatgggtaa gaagaacgaa gacttacgtc
    11461 gtgtattgat cgacgttttg cgaaaaatgt agtttttggt aaagaaagag actagtagtc
    11521 aatttgaatt gattactagt cttattttat gtttatgaaa tatgatttag cttaaaaatt
    11581 aaaaaaatat gtgtaaaaaa ttatttttgt gtagtaaaat taaaggatga taaatatttt
    11641 tattaatgat taatggagga gaagtatgag tttaaaagag ctatttaaaa gcaatgtgtt
    11701 tcgagcctgc attattatct tattgtatgt tttatacgca ttatttggga gttttagtga
    11761 atatttattt aaatatgctc tgaattcaat tactgctggt aattttaata catatgttta
    11821 ttggcaaata atgcagtttg ttttagcatt attcacttcg ttgcttttac caattactac
    11881 cgttgttttc actaggcaga cgcaaaacta tctgcataaa attcggcaag aaatcatgca
    11941 tcattactat gatgaaaaaa gtgatgaaaa agtctctagt atgcagaacc gattaacagc
    12001 caatttaaaa atcttatcag atgattatgc tacaccttgg attactattt taagtggggt
    12061 tttagagatt gtgattgcta ttattttact agcaagcatg aactggattc taattttggt
    12121 tactgccatt ttagctgtga ttacactttt tgctcctaaa attatggaga agaaaacatc
    12181 agctgccaca gataaagtaa ataaaaagaa tgaaaagctg ttaaatacaa ttgctcattg
    12241 gcttggtgga ttgcaggaac tacgtcgtta tagtgcatac agtcgtttgg ttaagcaaat
    12301 tcatcgatca agtagtgatt atgtggacgc aagtaagggt agtgcaaaat taagaagtgt
    12361 aagttatttg attaatgctt ttagcaattc aattgcacaa attggtatga gctttattgc
    12421 tggaatcatg tttttgctta atatgatttc attcggtgat tttgcagttg ctagtggttt
    12481 tgcatttacg attttttcag caatttggaa tattactcag tcgttaacgc aagttaagtc
    12541 aactaaggct ttacgcgaac agattaccga tttaagaaag caagttcctg atgaaaataa
    12601 agataaagta tcagcctacg gtcttaaagt ttcaggcttg tctgtaaaat acgatcaggg
    12661 ggaaacaatt ttttatcctg attttacaat aaaaaaaggg cagaaagttt tgcttactgg
    12721 cgattcagga acaggaaaat caaccttgtt taatgttttg ttaggtaagc taaaacctga
    12781 atctggtacg gtgacctatc tagatgaaaa tgaaactatc attcctgaag gaaaagctag
    12841 aattggcaat atgccgcaaa atccagtagt ttttcccgca acgatcaaag agaacattac
    12901 aatgtttaac gaaaatttgc aggataagct tcaagatgtt gttcaagcag ttcaactcca
    12961 atccgactta gccaaaatgc cagatggtgt taatacaaca attgatctaa aaagtgaaaa
    13021 tttgtctggt ggacaacggc aaaaagttgt tttagcgcga acggaaatac acgagcaatc
    13081 gtttgtttta atggatgaag taactagtgc gatcgatcaa aaagctaccg aaaaaatcat
    13141 tgatgaattg ctcaaaacag atcaaactat tttgatgatt gctcacaact ttacgccaga
    13201 attaaaagca aaatttgatc aagaaattaa attaaaaagt aagaaagggg ataaagtaag
    13261 atgaatttga aagcttttat taaaacaaat ccagttcgtt tctggttaac tgcaattggt
    13321 tggattatta ttcctgcttt atcaattacc aatacttacg ttgtacaaga agagacgaat
    13381 atccttttaa gtcgtaattg gactaagttt attttaatca atgttcttgc ttttctgatt
    13441 atgttagttg actatggtgt gagtgcttta gttgattatc agcagcaggc tcaggtacaa
    13501 gacttaaatg atcaagttag agataaaatt gttaagcgat attattatga cgggaaaaag
    13561 catactgttg cacagatgca aaatcgtttg actaatgatt tacaaatgct taacaataac
    13621 tactttatta atgtcttctt attgatttat ggtgtgtcaa cgatcgtttt tgttttaatt
    13681 tatcttattt tattgagttg gcaattattg ctggctattt gtttgatggt agctatttct
    13741 cttttgctgc caaagttaac agaaaagccg ttacaaaaag caacagaatt aatttctgac
    13801 agcaatcaaa aatatttaga tacattaaat gattggttat ctggtctgga tcaacttcaa
    13861 caatttttag ctggagctaa actattttcc gtaatagaaa aaacatcaaa aaaattagaa
    13921 gatgctaatg ttaagcaaac ggcttatatt aaactgctta atgccgtaaa tggaattgtt
    13981 tccgcggctt ttggtttagc attgtttgtg cttgctggtt ggttggttaa aaatcatcaa
    14041 attccaattg gtgccttatt ggtagtcggt aattttcggt attacttaaa tggaggaatt
    14101 gatacactta ctaacgggtt aggagcaatg aaaggtagta aaaaattact tgccgaagtt
    14161 gataaatctg ctagtgatat tccgatgcaa gctgaaaaag atgtagttat gcctaatgta
    14221 attaaaacaa aagatctagt tttaaagttc cctaatggag aaaaattgac ttatcctgat
    14281 ctggagatta agcaaggcga aaagatttta ttaactggcg attctggtgc aggtaagtct
    14341 actttgttta aactaatttt aggtgaactt aagcctagtg caggtaaagt tgtttatgag
    14401 gataaggctg gtaagaaaat taatcctgat ttgagtaaga taggctattt accgcaagat
    14461 ccagtagttt ttccagcatc gattgaagaa aatattacga tgtttaatga aaaactgaat
    14521 ggaaaagtta aacaagtaat aaatgaagtg aactttgctg atgatatcgc taagtttact
    14581 gaaggactag atgaaaagat taatcttgat aagctgaata tttccggagg tcaaagacaa
    14641 aaaattgtat tggctagagc aaaagttcac aatagtgata ttatcttgat tgatgaggga
    14701 actagtgcaa ttgatcagaa agctacaatg ttgattttga agaatttatt gaaaagcaaa
    14761 acgacgattg tttttattgc ccataacttt aatgaaggaa tgcatcagtt gtttgatcga
    14821 gagattcatt tagtaaaaga atagttgaag aaagacactg catttttagg gatgcagtgt
    14881 ctttacttta gtttggaaag atataggtat tgaaactgtt attcttattt attttaaaat
    14941 agcttagtaa ttgataagcc atccagtcag tatcgtctgc ttcaaaaaat attgaaggat
    15001 aattttgaaa cattttaact agaatagttt caataaaatt attagaacta aacctatccc
    15061 aagaacagat gtatgcaatc tcgttgtttt cagtgaatac aagattatct atttctccga
    15121 gttcattagt actataatat ccagtttttg ttggaacttc ttggataaac gtgtcaatat
    15181 tagcagttaa tggtgacaca gattgatgaa cttgtttgta atatttataa agtaattggc
    15241 aacatgttct gtaatcggga ctttctgtat tgaaaaaatg aagagataat ttgttattga
    15301 tctcaatttt taaatctttt ttgttaacgg taagcgtata acagtgtcgt ttgcagataa
    15361 aaccatttct taataaaaaa tctacgattg gattttcatt tgaatcaatc atgacttgca
    15421 atgcttggtg ctctgcttga actatttttg aaaatggaat atttacagag taatcactta
    15481 gattgaattt tagataaata tatttgttat gaaaaagatt gtgataagta gaaatagtgc
    15541 ctagatgctt atcgttatca gttactttgt agattttagg agatattttt tcaatttttg
    15601 tagtcatttt ttatcctttt gataattgaa attaattttt gatcggttcc gtttttaatt
    15661 atgaagttat aaatcggttc ataattgagc acagggaaaa taagatcagg atcaatttta
    15721 ggtataatgt caatcattga tttcttacta attacgttga gatttttaac ttcttgagca
    15781 tttcttatct ttctttttgc ttgtgaagga ggataacctt gtccccaagg ctgttcaaaa
    15841 agatttttta tagtctgctc aaaattgatt tcaccactcc aaccccaatt a
//
