LOCUS       gnlProkkaMCBINKMK_121  16600 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCBINKMK_121.
ACCESSION   gnlProkkaMCBINKMK_121
VERSION     gnlProkkaMCBINKMK_121
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:47:13
            Original ID  :: gnl|Prokka|MCBINKMK_121
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16600
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16600
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3564:11600]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3565..11600
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16600
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16600
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(166..1521)
                     /locus_tag="ctg23_1"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMICCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPVLLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(1701..2054)
                     /locus_tag="ctg23_2"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     WRFLAQRFQHHMQ"
     CDS             complement(2173..3552)
                     /locus_tag="ctg23_3"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPNRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQSYHVKASASGVLHLETALEGNQYV
                     PSGSVLARILSDLSEQTDADLKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQALYYGLAGQASVITGTKTYWDYFADKMFNY
                     R"
     CDS             complement(3565..5757)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 310; E-value: 5.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_4"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.9e-41, bitscore:
                     133.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1108.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQADMQLFDFEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPLRVRDVSFKYGFGQGVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLVAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             6387..7682
                     /locus_tag="ctg23_5"
                     /transl_table=11
                     /translation="MTVASNITYFFITFPIFATGIYFLTVIFDSRFRVIHITFWSIFGT
                     LLSLLLSTYGEVIFFIIYTCYIVKTTSRSNIFWIFIFMEANLVVITIQSSITQALISAK
                     AHLEPWTLISDSVINLAIIIAIFWLLSNKKEQILKLRDLVQEQNKLQHSVLIYTGATCA
                     SLYCFEATWELIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHDISSETRDVVSKAQQALSQVE
                     VNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQPGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             7687..8463
                     /locus_tag="ctg23_6"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLD
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRMGELRNILTGTRALS"
     CDS             complement(8582..8842)
                     /locus_tag="ctg23_7"
                     /transl_table=11
                     /translation="MNLYYATWLIFLATLFVFKDRKFVKRMISAILDDGNLGFGIRIVI
                     WLALLGLFFVTNHTDWPSAVLILLIVSAVILIDWHKTFQEE"
     CDS             complement(10312..10611)
                     /locus_tag="ctg23_8"
                     /transl_table=11
                     /translation="MNKLKWFAGGNERAEQAIQLIDELLRDFDDSSSHSDRLRTVLRNN
                     REALIHKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(10789..10947)
                     /locus_tag="ctg23_9"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLVIPVAAILGFLATDAWSHADELVAGV
                     KQGWERS"
     CDS             complement(11415..11600)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_10"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.6e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEMVDKFKGN"
     CDS             complement(11660..11845)
                     /locus_tag="ctg23_11"
                     /transl_table=11
                     /translation="MTTRTRLALKEISEEKLEMTTGGNVPLSNCSVDPPNERHPPAYEA
                     AFKYKLPIVHPIKVAT"
     CDS             complement(12237..12422)
                     /locus_tag="ctg23_12"
                     /transl_table=11
                     /translation="MPTRLTKLVDYGLIIATIIFAIYTVTSAIGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKKA"
     CDS             complement(12472..13278)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_13"
                     /sec_met_domain="Abi (E-value: 2.1e-14, bitscore: 46.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYTLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQAIVLKVTLRRPRLKPVVIWGLLLMLIGWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGGLIRAFYVAHHRHAKYQLLFCVGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEEFLARLSHS"
     CDS             complement(13599..14039)
                     /locus_tag="ctg23_14"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNSKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILTAIEGTAPLFKLHQGIDPAAF
                     VNGERVTSWLAASTNVLNQAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(14094..15521)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 326.4; E-value:
                     3.7e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg23_15"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQVIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAVQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAVRYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPILTLLISAVLWVAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSRVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTASLSKIADVFGQAMLIGVGMTIV
                     GLILVVALIIPAEKAAK"
     CDS             complement(15694..16026)
                     /locus_tag="ctg23_16"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKQAASGGLMETEAQEVVDEALDILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 ttataggaga gccgtccaga aagatactct tgtacaacct ttgccttgaa ctcacttgaa
       61 tatttagtca taaaaatgcc ccacaatcgt tagagtatct gtctaacaat tatggggcac
      121 ttcatttgaa gtggggttat ttgtgttgct aaaaagttat actgatcaat cgctttgccg
      181 ccagcgagaa tccataatca agcgagcggt aaacaagccc agcggtaaaa acataatgat
      241 aagtgcggca cgcgtcatcc attcggcacc gacgccaata ttattcaatc caatattgta
      301 aactgcccgg taaatataca agccaggcac catgatgacg atggatggca ctgttagcga
      361 aatccgcgga tagccatcga cgcgattaat cgccgacgca atcagtccgg ctaccaacgc
      421 gccgataaat gccgccgcag cagggggaat cgtgttgaga tccaccaatt caagccgcaa
      481 cgtattcgcc actgccccaa tcaacccggc ctggattgcc attcggcggg ggctgttaaa
      541 catcaccgag aatccgaaga ccccacaaaa gctggcaatg aggcgataaa ccaaaagaag
      601 gaccggactc aaacctaagt cgacaaagtt ttccgggcgt aaatggacaa ccatcgcgac
      661 cagccagcca accagcgaag ccacaatggt aatcatcaac gcatacagta gtcgttccat
      721 tcccgagcgc atatcctgct tcgaaatgtc cagcatactg gtgataaacg ggaaacccgg
      781 aatcacaaac aacatggcgc cgatataccc cgcttcatgc cgcgctgcaa tacccagtcc
      841 catttccagt ccgcgaaaag caataaaata aaccaaacag gcaaccgcca cactgacacc
      901 gatacaagcc agcagtgtcc agttacgccg aatcatgatt tcacgcagcc aattaccgat
      961 ccctgcacca acaaaacaac agatcatttc gataggaccg ccgcctagca aaaagacgaa
     1021 agcgcaacac gccaaggctg ctgccaatcc ggcgcgcaac ggatcgtaat tgccagacat
     1081 tttttgaatt tgatcaagtc gatggtgaat atcccggacg gtttgagtcg catactcttt
     1141 gtcaaaatga cgcacaaaac gttccaacgc atccaacttg tcagtattca caccgctttt
     1201 tggcagtgaa agcacctcag aataggcatg gttattgcta aagcaggtat acgataagga
     1261 aattaggcca atatctgctg agcacgacat ccgcaatgct cgagcaacgg tgttcatcgc
     1321 ctcacgcacg cgccacgccc cggtaccaca cgccagcaac atgatcccga ctcggccgac
     1381 aagtgacgcg cgctcttcaa gggtggcatg atcggcttgt cgctcttcgc tgacaatcac
     1441 gtcataccac gggatctgca tatgatgttt ttctgaaagc ggttggtctc cccgatccgc
     1501 ttggttatct tttgccttca taactcgtgc taatccttct tcttataggg attgtctttt
     1561 tcaaaaaaat tgaaaataaa cattcactat tctagcacaa ttcataacag ggtgtatttt
     1621 tgactttttg aaactaacgg atttgaccgc cttattcatg acaagcatgc acaaattagc
     1681 aatcatttct cggtctcaac ttattgcata tgatgttgga atcgctgcgc cagaaaacgc
     1741 cagattcgca aaaagcgacg gggatcttcc ttcttctgtc cattggctat ccgtcgtagt
     1801 tcgtcaattg catcgcgacc ttcttgactc aaccgtacac tttcagtcgt gaggataaaa
     1861 tcaattctta gtatcatccg aaaaacatgt cgtcgtaatt catagccatg gaaaccatcg
     1921 cggataatct cttccttggt tctttccaca acttcttcaa tattcgtttg gcggatgagc
     1981 tgcggttgtt catgtaattc atgcaacagg cagtcgatat agccttttgt ttctaattct
     2041 tcctcgtaat ccatacgccg atcaccgcct ttcatttgac taacttgatc cgcatcgttt
     2101 ttttatggtc attttcttaa ataatgggca tcgcattttc gctactaaac gacaaaagcg
     2161 gtaaataccg attcatcgat agttaaacat cttatctgca aagtaatccc aataagtctt
     2221 tgtgccggtg ataacagatg cttgaccggc taatccataa taaagggcct gccgctgcga
     2281 tttagataat ttcacccgcg ccttgaccgt aaagaagttg ccaactttcg gatcgcgtgt
     2341 cggggcgacg tcaatcgcat aaacccggcc atctaatatg gtaggggtcg gcacattctc
     2401 agcaattcgc aggcgtactt tctgcccacg cttgatgctc atgatttctg tcggcgaaac
     2461 acccaatttt aagtcggcat ccgtttgttc cgataagtcc gacagaattc gtgccaacac
     2521 gcttcctgaa gggacgtatt gattcccttc caaggcagtt tctaaatgca aaacgccact
     2581 ggcacttgct ttgacatgat agctttgagt ttcatcattc aaggtagcta acttagcctc
     2641 gtctgcttgg acctgttgtt gaaccttcgt ctgttccgca acggctgttt gctgcaaccg
     2701 actttgtaat gcggttagat tagcctgagt ctcccccgct ttttgagccg atacatctgc
     2761 ttgtttttga ccggcccgtt gctgctctaa agacgtcaaa ttggtttgtt cctcatccaa
     2821 ctgtgtctgt aattgagcaa ggtactggcg tttaaggttc gcctgtgcct ccgcgtcggt
     2881 attttttatc tcactttcat attgttgata aaggtagtga taggcgtggc gattgggcaa
     2941 gggtttgttc gcctgaatcg ccgcttttgc ctcggagata gcggccattt ttgcttggct
     3001 cgtttggata ctggcgctta gtaaccgatc aatctctttg tttttttcac tagcgacggt
     3061 ttgggttgcc tgctcagcct ctgctgtcag tgtcagcact cggcgttgac tcagataatc
     3121 ttgcacctgt tgttgatagc cgaatcggtc tgcctttgaa aaaagatctt tgttttcggt
     3181 aacactttgt ttcaaaacat ccaattgctg ctgttgctct tttagcgttg ccagttgctg
     3241 cttgagtaat ttaatttgtg ttggattggc gacatcgtgg taaacaagta aggtctcgcc
     3301 tttcttcacg cgcttgcctt ctttcatgcg gttcgagacg atccgattgg cggccgtcgc
     3361 ctgaaccgtc acggctgcct ttaccggttc aatttcggca gctgtcagca cagttacctc
     3421 gcgccgagca aagatcagaa acaatagcaa gcctaagaaa agaatcgtac taggcataat
     3481 aatcattgtt gaaaaattgc gaaagcggtg ctggtaatat tcggtcgttg caagtttttt
     3541 gggatccatc atctaaagct cacctcactc atgaaccagg cgcgcgtaat aaccgtcttg
     3601 ggctaacaac gtcgcatggt caccttgttc cacaattttg ccatgatcca tcaccacaat
     3661 ttgttcggtt ttagccgcaa tggttaagcg atgggcaaca aaaataatgg tccgatccgt
     3721 cattgccagc aagcgatcga caatttttcg ctctgtaatg gtatccagac tgctggtcga
     3781 ttcgtcaaaa atgagtactt ttgccggtga taacaaggct cgtgcaatcg ccagccgctg
     3841 cttctgaccc cctgataaaa tgctgccgct ttctgacagt ttggtctgcc actgctgcgg
     3901 taagtttgcg atgtctgcag caatttccgc aaccaaacac gcctgcgtca agtcttgttc
     3961 cgaaacatcc gaacggctac ctaacgtcaa attctccaac accgtccccg aaaaaataaa
     4021 tggatcctga ggtacatatt caatatattg ccgtaatgtt gtgagattaa tatctttgac
     4081 cggaatacca ttaaacgtga tggttccttt atcggcatca accgggtaaa agccaactaa
     4141 taattttgct aatgtcgact taccagaacc gctcatgccg acgatggtat atttagcatt
     4201 ttccgggact tcaaggttga cgtttttcaa cacaccttgg ccaaaaccat atttaaacga
     4261 aacatcccga acgcgtaacg ggccttcgat taaatgccgc tccgtcaagt gccgctgttc
     4321 tttgaattcc gattcaacca gataaacctc attcaaacga ttgttagcaa cccgcgccat
     4381 ttgtaacttt ggctgtaggt tgatgatgct ttcaagcgga ttcgtaaagt atgacagcag
     4441 cgcattaaag gtcagcatct gccccaaact catccgattg gcaatcacca aacttgcccc
     4501 aatccacaac accacaacgt tcaacgccag cttcaacaga cctttaatcg cttgctgtaa
     4561 ttgatctgcc ttagtgtaac taaacgattt cttcagataa gttagaaatt cccgatcaac
     4621 ccgttcatag ctaactcgtt cgccggtcag ggacttgatg gtttcaatgc cattcaaatc
     4681 ttcaataatc gatgaactca agattgcgtt actttccatc gtctcttggt tcaaccgatc
     4741 aaacggccgc tgaaatgcaa aaacaatcac caaataacac ggcacggcaa tcaatgacac
     4801 taaaaacaaa gtcccatttt ggatccctag aacaatgcct aatattagga caatccagac
     4861 atccaaaaat aacgtcataa tcgtattcgc cagcgcatca ataattttat tcgcgtccgc
     4921 aaaccgcgac acaatctctc cggtccgccg agttgaaaaa aacgacatcg gcaattcata
     4981 taaatggcgc acatacccta aaatgacatc aatcgcaagt cgctgcccca acaccgccat
     5041 caaaaaattc tggccataag tcaacacagc ttgcagcaag taagccacca aaaggccact
     5101 agcaatcatc cccatcgtcg tccgcatggc attcggtata tacgtatcaa taatagactg
     5161 caaaaaatac gacccaacga tactaatgac cgtaatcaat accgcggcca gaataatgtt
     5221 cgcgatgatg cctttctgct tagctagcat gggtacaaac gcaaacaaac tgcctttgtc
     5281 ctccttacgc ggctgatact gcggcgccgg tgcaataaag atggccacac ccgaccattc
     5341 tttttcaaac acctctcgcg aaagccaggt catgcgcact gacgggtcag gatcgccaat
     5401 cagaatactc gtgcgcgttg ccttaaaaac aacataataa tgaagcaatt caccacgctt
     5461 cagcacatgg gcaataaacg gataaggcac atcctcaaaa tcaaacaact gcatatccgc
     5521 ctgcaccggt ttcgtctcaa acgctagtgc ttcagcggcc cgaacaattc ccaaagcagt
     5581 cgtgccatcc tgatttgtct tcgctaactc gcgcaagtgg gctaacgaat agtccgaccc
     5641 attgtattta agcagcatgt ttaacgcagc cacaccacag tcacgctcgt caacttgtgc
     5701 ggtgtagaag cgtttgtagt aggtgatctg gcctagtttt ggggtgtatt taaccattaa
     5761 ctctcctcgc ttattaagcc attagattca ggcctctttt atgaacttat atgtcaaaac
     5821 agttagccaa agatacaggt gaagtatcgc aaacttttgc ttaacagctt tgatctaagt
     5881 gtcgtaagat ttagtttttt gcatttaaaa tatgtggtag tatattttaa agcagataaa
     5941 atagcatata aaaataaata ttcattttaa aagtactttt atatttaaat atttattctt
     6001 atatgcttaa agcaattatg tgctcagctt tttcaaaaga cgtatatggc tttaatgctt
     6061 tctttgaaac tgttctatca gccatttttt tatattttca aacgcttggc ttgttggtcg
     6121 caaattgcca ccatgtattt gtacgagccg ctcatccgaa atcacgctgt ttttcatctg
     6181 actctgaaac ccctttttgt tgttcacttc aaactacctc ctatgattta ttcttctgtt
     6241 tttaacctaa catgtcgtga gctttttggg gcatacaaaa aataaacgtc gtgttttggc
     6301 catttaacgt cattgtgtca gcagatgacg tcatttatct tcattcaaaa cttgccatac
     6361 tttcataact tgcggaggtt ttctatatga cagtggcgtc aaacataacc tacttcttta
     6421 taacttttcc tatttttgcg actggaattt actttcttac cgtcattttc gacagccgtt
     6481 tcagagttat ccacatcact ttttggtcaa tcttcggaac ccttctgtct ttgctccttt
     6541 caacttatgg cgaggtcata ttctttataa tctatacgtg ctatatagtt aagaccactt
     6601 cacgttctaa tattttctgg atttttatct ttatggaagc caaccttgtt gttatcacaa
     6661 ttcaatcctc tattacacaa gccttgatct cagctaaagc acaccttgag ccttggacat
     6721 taatttccga ctcagttatt aacttggcaa taatcatcgc gattttctgg ttactttcta
     6781 acaagaaaga gcaaatttta aaactgcgcg acctagttca ggaacagaat aaactgcaac
     6841 attcagttct gatctacaca ggcgcaacct gtgcgtcact atactgtttt gaggctactt
     6901 gggagctaat cgatctcaac aacttcttat cttggttaag tcttggcgta ttcctacttt
     6961 cagttgtgat cagcctttat tcaattttct ttatcttaaa atcctataaa tattatatag
     7021 agctcatctg gattaaacgg gcagaaagtt cccagcgtgc ttactatgca acgttagcac
     7081 agcaacaaaa gagaacggac aagctccttc atgattacaa aaacttatta gccacgttgc
     7141 agttgtcaat ggatcaatca actcacgaca tttcttctga gacgcgagac gttgtttcaa
     7201 aggcacaaca agcgctatct caagtcgagg tcaatcaaga aaccttcgat gcaattaaaa
     7261 gcgattcgct gaaaagtcta ctctatttaa aatggacaga agcgctacat cagaatatca
     7321 agatgtacgt tcacatcgaa gggatcattg aaccgctcga tagcagcact tcattcgcgg
     7381 tcattcgcgc actcggtatt ttaattgaca acgctttaga agaaacaagc cgctccggaa
     7441 actcaaagtt tagtgtctta ttaatcaatt caagctcgta cctggaagtt aatgtcatca
     7501 atgacgtgac cgcgggattt gaactatcaa atcttaacca gcctggattt accaccaaag
     7561 gccatggtcg cggaaagggg ttgaccatta ttaacgagct gattgaacaa aacaaaaaaa
     7621 tcagccttaa gaaaaaggtc aaagataacc agttgaaaat cacacttttt gtatggaggt
     7681 aactttatgt ctaaaaacaa aacgatccta aacatttata ttctcgaaga caaccctgac
     7741 tatctaacct ttatccaaga aactgtgcag cagtaccttc tgattgaaga actacccgcc
     7801 aagatccggc tggcaacaac gtcagcaacc gaactgctcg caactattga ttggtcagcc
     7861 atcaacgata gtatcttcct ccttgatatc gagctgggag attcagcgac aagcggcgta
     7921 gatgtagcca cagccattcg gaaaaagtca tattatgtcg atatcctctt catcactagc
     7981 catgtagatg aagctttaag gattttagag cacaaaatcg caccgttgga catgatcaat
     8041 aagaactcac cttcgaagac agaaaagaaa attcgaaata acattcttta tgcaataaaa
     8101 cggctaaagg cgcgtcaggt cgcatctccc agattgttta gctacagcat caactccagc
     8161 attttttcac ttgatatgga tgagctcatc tatattcaaa ctgctcccgg tgtctcaggg
     8221 acactggagc ttcatgcaga aaatgaaatc acaacctttc ccggcaacct taaggaacta
     8281 gcgaccaaat ataccaactt atgtcgatgc cataagagta tcctgattaa tcccgcacat
     8341 gttttgcgtc tggacatcac aaaccgattc gtttatatgg acaatcaaga taaacttgag
     8401 gtcagtattc ggagaatggg cgagttgcgc aacatcttaa caggcacacg ggctttatct
     8461 taagaagagt gtgactgggc aatcatccta gatttctgtt aatcaacaca gctgaacgca
     8521 caaataacgc atcctcaata tcaagggtgc gttatttggt ggtttataca ggttggaaat
     8581 actattcctc ctgaaaggtt ttatgccaat caattaaaat tactgcacta acgatgagca
     8641 gtataaggac tgccgaaggc caatcagtgt gatttgtgac aaagaaaagc cctaaaagag
     8701 ccaaccatat gacaattctg ataccaaatc ctaaatttcc atcatctaaa attgcggaaa
     8761 tcattctttt gacaaatttg cgatctttga aaacaaacaa agttgccaaa aagataagcc
     8821 atgttgcgta ataaagattc acagtgctac tccttcatca gctctacttc aaccaacgcg
     8881 ctatcgactg acccgtttga taaccagcgt cataaatccc ctttaaaatt cccggtgaaa
     8941 agtaccaaaa cgacattatt aaaaccccaa tggcgacaag caacgacact ttctgttgga
     9001 atgataatct tgcaaattga tcgattacgc tcacctcgtt tacaaacaga cttattttta
     9061 cttctttcag caatccatta gtaacctgtt ctttatgttc tcccaccttc taagaaaaag
     9121 gcaatatact aatggccaac tgcatcaatt gggaacattt ctcccaaaaa gatgttcgcg
     9181 catgaagccg atgtcttaag aggtctatca tctgccagct gatcgcagtt acaaatacga
     9241 atgtgaagaa aaatgccaga atcaaaagca tagaatataa cacaactgtc ataagcaaag
     9301 ctccttgagt cttcctttaa acttacattg aggcggcaaa ttagcgagca caggttcgga
     9361 gatactatac gttctgctag ggtcggtcat acaagcaagg agtcacaaaa aatgacacca
     9421 ttttagctat ttaatgctgt ttcctaaagc ccttttgctg tcagggaaaa aacaattgtt
     9481 ggttttgaaa gctcatcttg tttagcatct gttctgccat actcacgcgc aagatctcct
     9541 gatttgtatt tttgtttcaa tacaaatcag gagacctttt gcggtttttg gctgatagaa
     9601 catagggtaa caagattctg acactaaaag cagtttccaa atatcagtag tgtcacctaa
     9661 aatctcattt gccgtcatga acagtcgaca ttgcattatt atggcctggc agatagctgt
     9721 gtcacaatag ttgctgtctc tcggtgctga caggcttcct actgacaatg acgctgccgc
     9781 cttaccaata cttcgaaatc aaacaaagaa aatttgttat ttagagcgtt tatgatcttt
     9841 aacccttgaa gatgcgacac ttattttaga aaaaagaatc aaaacaatga agattgaaag
     9901 catctcaatg aacgcccgga cgatgaaaaa atcaaaaccc aagcaatcga caatcagctt
     9961 gtttaagcta tcactgagcg agaacccgcc gaaaaagata caaacgataa tccagaaaga
    10021 agcttcatta agccatgtgt gcatagtttt aagaatcgtc atcgtacctc cgctttgctc
    10081 atcactaaat catttatcga ccgatcagtt ttggctctgt ctttttaagt tagaccgtta
    10141 tattcgaaac tagtttgcca aagtcgccgt tataaattgg acaacctttt aggcatcatc
    10201 cattgacaac aagcccatac caaccagcat cgcaatcgga gtttgatctg caccaaatga
    10261 atcagtgaac ctaaccataa tcaagcgcgc tcaccgtttt agtagtggct tctagtaccc
    10321 atatctgata ttcgccagcg aagaaagctg ctcgaattta tcagattgtt gcttggttaa
    10381 caaaatattg ttttgcaaca gggcattaga gatttctaga ttcatgcggc ttaaaataaa
    10441 tggaaccgct gcttgcttgt gaattaaggc ctctctattg ttccttagca ctgtccgtaa
    10501 gcgatcacta tgggaagaac tgtcatcgaa gtcgcgaagc agctcatcga taagctgtat
    10561 cgcttgttca gctcgttcat tcccgccagc aaaccatttc aatttgttca tcattcactc
    10621 caaaaaacgt tgtgcttgtg catcttcact tgtaacacgt ttggcgccgt gcattgccag
    10681 atctgccgta gcaataacgg taagtgcgtg ctcgcccaca gataaaaact tgttctgggg
    10741 agagatactt ttacaacggc gaaatcgcta aaaatcaacg caccgttatt acgatcgttc
    10801 ccatccttgc ttgaccccag ctaccagctc atcagcatgg ctccacgcat ctgttgccag
    10861 aaatccaaga atggcagcga cagggattac gagcggtccg ataccgccgg aaatcttact
    10921 caattcagct tcattcaact tagtcattaa aattaccccc ttgtatttgt agaaactact
    10981 cgccagttga tccaaaagtc cttgttatgg atatcgtggc gataaaacac tcatcaaccg
    11041 cacaactttt tgcaaataca accattgagt catcatcggc atgcctggat taaggccact
    11101 tgaccttcac catcgaaatt cgactactgg atttgtatgg cagcattaca gcgtacggct
    11161 taggcattga acggaacact caaagtttaa gcgtaggtaa taaaccagat ggcattcaaa
    11221 atataagcac gtttaaaggc tatctgatgc ccactgtcga gatatttatc attcccaacg
    11281 cgatagtgac catctttttt acagcacgta tataccaaaa cacctaatag atataccaag
    11341 ataaacgtag ctaacattaa aagatttatc ttattcatac gttcgcccgt tcgagtgcct
    11401 attcatcgcg gatgctaatt gcctttgaac ttgtcaacca tctctttggc aggaccaatg
    11461 gctggtgcaa acatggcgcc ttcagcccaa gaacgcgcgg ttgaaccaat agccttcccg
    11521 ataaaggtcc acagattacc attatcgcca ccagaaatgc ttgctaagtc agctgtgttt
    11581 aaagttttta aatgatccat gtttttcctc cttttttctt tatgagcctg tcaatgtatt
    11641 aatcagccca ggttattgct taagtcgcca ccttaattgg atgaacaatc ggcagtttat
    11701 acttaaatgc cgcttcgtaa gctggcggat ggcgttcgtt tggtggatcc acactgcaat
    11761 tggataaagg aacattccca ccggtcgtca tttcaagctt ttcttctgag atttctttca
    11821 aagctagccg cgttcgtgtg gtcatcccat ttttctcctt tccctttgtt agaaggactt
    11881 cccttcttcc tcatcaatat aaagtagaca gccaggtttg tgggaatgaa ttttttaacg
    11941 tcgatttttg caagaaaatc gtcgtaaaaa acctaatttt gacgtttatc gttaaaaacc
    12001 cggcgattat ttgatattgc cgccttctct tcaaaactca agcaactgca actgtaactg
    12061 tatttacttt tacccatgtc tttttcgcca ctgtgagcat ccagtcttaa gccaacttag
    12121 aaaggcgatc aggctcgcgg ccagcatgtg catccattca ccgggaaagt gataacaaac
    12181 tgcacacata taaccgacaa aaaatgttaa taaacagcgc caaaatcttt tttgattcac
    12241 gctttcttct gcttttcctc ccgctcactc aacagcatca acaacgtcat caaaatcaac
    12301 attggcgtca caaaactgcc gtgattggtc cacccaattg ccgatgtgac cgtataaatg
    12361 gcgaaaataa tggtagcgat tatcaaccca taatcgacta gtttagtcag tcgcgtaggc
    12421 atcgtttttc tccttaaact cgttctatca taattgatac agacagccgc gctacgaatg
    12481 cgataaccgt gccagaaact cttcattgtt ttggccacgg cgaaaaagtc gcagtgcaat
    12541 cgctaggtaa atcccggcaa taaggaatgc gtgaacaatc gtcatcgtta tagcgttggg
    12601 atcactaggc gcttctttcg gatacggtcc actaaccaaa gtgataacaa aatcaatcaa
    12661 aaaatggatc aatattggca taagcaacga tccgtagcga atataaagtg ctgcaaaaat
    12721 agcccccatg ccaaatgcct ggatcacttg ggcaattgtt atcacaagcc cttgagcagg
    12781 caaattactc aggtgagcca atgaaaaaac caagctgctt aaccctacgc aaaataagag
    12841 ttggtatttg gcatggcgat gatgggcaac ataaaacgcc cgaatcaaac cgccaagcat
    12901 gacgccacga aacaaatact cttctggaac agcggcaatg gtaccaatca cagctgcttg
    12961 caagacgtca atcggtgttc gatttgtaac cgtgaaccac ccgataagca tcaagagcag
    13021 tccccagatg acaaccggct tcaatcgtgg ccgcctaagt gtcactttca agacgatagc
    13081 ttgtttcagc agcagccagt taagtgcgat catcaccagt aaaatgatgg ctttaaataa
    13141 gatattccca gcccagaagt ccaatttcag cgtgtaaact gctggaatta aaagcagctg
    13201 gctgattagc acaaccaaaa gcaagatata taaaacgcaa aatcctggcg acaatagcaa
    13261 atgacgtttt ctttccattt attcaccttc actcgcacgt ttcaatgcaa agcagcttcg
    13321 atatcgctac ccacaatata ccgagtcttc gcatgttacg gatcattaac ttttaaacgt
    13381 cgggttttca ccgataatcg ttgtgttttg aaacttgaca acgcgttaat cgtccccatt
    13441 tccgaaaagg tcggcaaatg gaggcgcact tgctgactat ttactgactg ccccacagtt
    13501 gcacgatcct gaaaatgccg taagcaaaat cgcctcatcc aatgccaacg cgccaacgtc
    13561 agtcttggat gaggcgatga aaagttagag ttcgatattt acgcttctgc ggcttcagcc
    13621 aaatcagcaa tgctcgtctg ctttagcact tgcaccatag catcttcggc ttggtttaaa
    13681 acattggtgc ttgccgctaa ccagctcgtg acgcgctcgc cgttgacaaa cgcagctgga
    13741 tcgattccct gatgaagctt aaataacggt gccgtccctt caatagccgt taagatttcg
    13801 taaactgtaa tcgtttgtgg cgttttggct aatcgcaaac cgccattgag accggttttc
    13861 gacgttaaaa taccactttt tttaagtgta gacgaaattt ttttaatgct aggaaccgga
    13921 atgtttagca tttcggaaat cttttgaatt gataaatagt cttcgtgttg tgcttgggac
    13981 tttgagttga cataagccgt aatttcaagt gcttgcgaga atgcgactga aaaagccatc
    14041 gaatatacct cccattaggc gattgtgtat attctattat accaatgata ccgttacttg
    14101 gcggcttttt ctgccggaat aatgagcgcg acgacaagta ttaagccaac aatggtcatg
    14161 ccaacgccaa tcaacattgc ctgtccgaat acatcggcaa ttttagataa gctggcggtc
    14221 gaggccgcaa aaattgccag tcctaaagcg ccgccaaatt gtcgggcggt gttgtagacg
    14281 cctgatgcag ctcccgaaat ttccggccga attctagcca aacctgaagt agcgagtgtg
    14341 gcaaatgcca gcgcgaatcc taccgcaaat ccgagtgttc cgagtaacaa aaaccagtaa
    14401 ttggcaaacc gtgatgccac tgccagttca gccaatgaaa gtagcaccgt gacaaatccg
    14461 aagatcatga cccttgagtt acgccaccga tcaacgaagg tccgggcctt gactgccaca
    14521 atgaacagta ggatggccat tggcaccatg cctaacgcag tcataaatgg cgttaatcct
    14581 aagacgcctt gcataaactg aggtgtgtag aaccaaaagc cgattgcagc ggcactaaac
    14641 aacagagaac tgacataaga agccatccgt tccctatccg taaagatttc cagtggcatt
    14701 gtcgggtggg caacgcgacc ttgactagca atgaatgcaa cccaaagaac tgctgaaatc
    14761 agcaacgtga ggattggcca tggactgcca tctaacccat atgagattga agtcatcgct
    14821 aatactgaca agatcgtacc aatccagtca atctttccgg tttggcgttt tgcactaggt
    14881 aaatatctta ccgcaatacc aaccatgatt aacgcgatcg gaccattcat gtagaaaccg
    14941 acccgccatg acgcaaatgt tgcaaagaag ccgccaatga ctaaaccaac cgctgcaccg
    15001 gctccaatca cagaggcgta gtagccaatc gcccgctgcc gtgcttttcc ttgaaaggtg
    15061 tcggttaaca atgctaaaca gttcggtgca agaatggccg cgcccacgcc ttgcacagcg
    15121 cgaaagctaa tcatgacaag cgcattagta gctgccccga ctgccagact gccaaccccg
    15181 aaaatagcta aactcgcaat gaataatggc ttgcgtccgt atatatcgcc taatttaccg
    15241 cctactagca tcagcccagc ataagttagc gcataggcca cctgcaccca agacaacgcg
    15301 ccagcattca aatgcaattg taccgccatt ttgacggtac ctgtgtaaac aatcgatgtg
    15361 tcaagcacac ctagaaaagc cccaatcagt gccagaccta aaataatgac ttgagtcgct
    15421 gacatgcgct gcgattgggt gattgccgca tctgtttcct caatgacggt gtcgtcagcc
    15481 aggccatcat tgattaattc cttgtcttct tctttgctca tatgagatgc ccctttctat
    15541 ggttcactta gtatattccg tttatactaa tatggcaaat cttttttgag caaaaaaacc
    15601 acgtgttcct taattctgtg gaaacacgcg gctacaagcg aattcttttc gggccggtta
    15661 ctggaatcag accatggctt gggcaacaac tgtctaaata ataaagtgcg gcccgcctac
    15721 ctgactcaat tcgccatgaa tgtcattttc cataaagtct tttaccgcct gccaccactg
    15781 attggcctct gctgaaagtt tcattccttg caagccgatt aatcgcgtaa accgtgcgta
    15841 tagtcgcgac aaggcgtaat ctgcggctcg attcttgagc acattaggcc gctttaaaat
    15901 atctaaggcc tcatccacaa cttcctgtgc ttctgtctcc atcaagccac cactagccgc
    15961 ttgtttcaga ctcaggttta atccggtcaa aataaacaga atctgatttc gttgcaccat
    16021 attcatgagc gatcctccat gtctggtaga taaatgtttg caatgagata atgttttctt
    16081 gaattgctaa ctgcaatata ccaaatctat caagcttcgg gtcaaacttt cgataaacgt
    16141 cgccttttcg ccgattaacg ttattgcgga catgaatcgc ccggtccaaa gcacatagaa
    16201 aaagccgtgg tgcattaacc acgactaatc ggaagcgcgt atttcagcat agtcgtaaaa
    16261 aggctgaaat gacacagttc atcagcatca aacaaattca tattccatcc ggctacttaa
    16321 tgtccgccac cccagacaat tggaaaggcg acgagcccag cagccagcgc ctgatcgcga
    16381 taacgcttgg cattgacctg atctgccggc acatccgcct tgatcgcatt gaaaatggcg
    16441 atcatctcgt ctggaatcgt gtgatgaatg agataatact tggaaatatc atgcgatagc
    16501 tgggtcacga ctgcgacata agttgtttta tcctctgcat cttccagttg tttcgcgttg
    16561 gattcgatta tttgctttaa tttggcatca gctttcacgg
//
