GCA_039414055.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaNCGNHNBL_1 (original name was: gnl|Prokka|NCGNHNBL_1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	terpene	368,829	389,710

gnlProkkaNCGNHNBL_4 (original name was: gnl|Prokka|NCGNHNBL_4)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	cyclic-lactone-autoinducer	191,658	212,363

gnlProkkaNCGNHNBL_8 (original name was: gnl|Prokka|NCGNHNBL_8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	T3PKS	1	33,588

gnlProkkaNCGNHNBL_13 (original name was: gnl|Prokka|NCGNHNBL_13)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	RiPP-like	60,500	72,650

gnlProkkaNCGNHNBL_14 (original name was: gnl|Prokka|NCGNHNBL_14)

Region	Type	From	To	Most similar known cluster		Similarity
Region 14.1	NRPS	52,220	92,262	mutanocyclin/leuvalin/tyrvalin	NRP	46%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	terpene	368,829	389,710
Region 4.1	cyclic-lactone-autoinducer	191,658	212,363
Region 8.1	T3PKS	1	33,588
Region 13.1	RiPP-like	60,500	72,650
Region 14.1	NRPS	52,220	92,262	mutanocyclin/leuvalin/tyrvalin	NRP	46%

Compact view

gnlProkkaNCGNHNBL_1 - Region 1 - terpene

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Location: 368,829 - 389,710 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNCGNHNBL_4 - Region 1 - cyclic-lactone-autoinducer

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Location: 191,658 - 212,363 nt. (total: 20,706 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNCGNHNBL_8 - Region 1 - T3PKS

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Location: 1 - 33,588 nt. (total: 33,588 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNCGNHNBL_13 - Region 1 - RiPP-like

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Location: 60,500 - 72,650 nt. (total: 12,151 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaNCGNHNBL_14 - Region 1 - NRPS

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Location: 52,220 - 92,262 nt. (total: 40,043 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 52219 - 92262:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg14_73

Search NORINE for peptide: strict or relaxed

AMP-binding (447..839): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DYFTLGLVVK
Nearest Stachelhaus code(s):: Leu DYFTFGLIIK (68% 8Å match); OMe-Trp DAFTLGCVFK (56% 8Å match)
Stachelhaus code match:: 70% (weak)