LOCUS       c00158_gnlPro..        15421 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBHJJMBE_158.
ACCESSION   c00158_gnlPro..
VERSION     c00158_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 22:26:47
            Original ID  :: gnl|Prokka|HBHJJMBE_158
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15421
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15421
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2176:5421]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2177..5421
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15421
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15421
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(122..1054)
                     /locus_tag="ctg158_1"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGGPNDE
                     TKFVLDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELISAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
     CDS             complement(1084..2052)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg158_2"
                     /sec_met_domain="LysR_substrate (E-value: 3e-26, bitscore:
                     83.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.8e-19, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWSTYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             complement(2177..3028)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-25, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             complement(3160..5421)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg158_4"
                     /sec_met_domain="Gly_radical (E-value: 2.2e-41, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 9.3e-244, bitscore:
                     802.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             complement(5673..8117)
                     /locus_tag="ctg158_5"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVIAAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             complement(8124..10136)
                     /locus_tag="ctg158_6"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKHAFEEHFINGGHPDGSLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLRERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             10853..11560
                     /locus_tag="ctg158_7"
                     /transl_table=11
                     /translation="MYVRFILLTYHSKVKNAKIVSSLRGGAHLILVLCFILAYFIGAIP
                     FGVVIGKLFYHTDIRKGGSHNIGTTNAYRMLGPVGGSIVLVLDILKGTLAASLPILFGI
                     EHHWLVLIVGLAAVFGHTFSIYIRFKGGKAVATSAGILLAYNPPFFVIAFAIWFSLILL
                     TSMVSVASTLGMVLITAWSLVYHDWLLTTVACGLLVVFLIKHRANFKRIKAGDENMVPF
                     GLGQYLRQHRGRS"
     CDS             complement(11642..12520)
                     /locus_tag="ctg158_8"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(12556..13965)
                     /locus_tag="ctg158_9"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGSVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             complement(14009..14533)
                     /locus_tag="ctg158_10"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
ORIGIN
        1 ggagaaccgc ctcaaatgat aaatttattc ttcaacacca gttgacgtag agccacaaaa
       61 aagccgcaac tggctagctg cgactttcct tagaacaatt gtgtgcaatt aaagatgaaa
      121 gttaaccttc aaacgtgctc tgcattggcg gaacgacctg ttttttgcgg gaaacaaccc
      181 caggcaatgc caaacgcgcg tccttgtcga actgttcgtt gaaagcactg gcgattttat
      241 cgcggtcagc accgactgcg aaaccagttg aattgctgtc caagatgtca gtggcaatca
      301 gcaggaaatc gtcgtagcct ttcgcctgcg cctctttggt catggcactg atcaattcgt
      361 cctgacgtgc gtaaatgtcg ttcagatcaa cggtattgac ctgtccgatg cgaatagact
      421 tgccgcccat ggtgaaactc ttagcatcgc cttcgataat gtccatatct gacttggcgg
      481 ccaaattagt acctgccttc agcatggcaa gaccatatga ctgcaaatca attccggcaa
      541 tcttcgccat ttctggcaaa atcttcttat ccttatcggt tgcggtcggc gatttcaaca
      601 acagcgtgtc tgaaatcaaa ccagaagcca tcaaaccagc caatgttggc gaaatcttga
      661 agccatattc ttggaacatc tcaaaaatga cggtattggt gctgccaacc ggttctgctc
      721 ggtaaaacag cggcgctgcc gtgtggaagt tagcgatgcg atgatggtcg acaacagaat
      781 caatcgtcac gtcttcgata tcactgacac tttgttgaaa ttcgttgtga tcaaccaaca
      841 tgacatgatc cgtctcgttg gctgccgtct tgataacccg cggtgcctga accttaaagt
      901 gatcaaggac gaacttagtt tcatcgttcg gtccgcctaa tgctaccgcc tcaacatccg
      961 tgttgcctgc ctgtttctga aattctgccc agctcatggc actcgtaatc gcgtcggtgt
     1021 ccgggttctg atgcccaaaa atcaaagtcg tcatcttatc tgatcgctcc tcaactgaat
     1081 agtttactta tcaagtttaa cacggttttc actgacccgc gacaagtaat ctttttcctt
     1141 cagataatcg tcaaaggtct ggaagaagtt cgagatccgc ggaatgtcag ctttctcttt
     1201 gcgataaaca aaagaaatct caaagcgaat ggccggatca aacgcaatag cataggcctt
     1261 gatttgatca gcgcgtgccc gaacaaaact ggttggtaag gccgtgttga cccctgacaa
     1321 gttaacgaat tgggttaact gatatggcgt ggtgaaatgt gcgaccacgt gcgggaaatc
     1381 aaccatttga ttcttgtacg cctcacgcag aagctgtcca aggaaatagt cgtcaggata
     1441 agttgaccaa ggttcagcta aagtatcttt gaaatggatt cgcttacggt tagccaaggc
     1501 gtcatcgtgg tgcaagaaca gcaattgttc atcaataatt ttcttgctgg cgtatggttt
     1561 ccagttctta atggtctcat ctggcagatt catgatagcc aaatcaatct ggttgttttc
     1621 caaggattcc caaatttcgt gacgggtcat catccgtagc gttacttcaa cttcaggatt
     1681 cagttgatag taatgagcaa tgaacgcaat aaaggcgcta tcctcaattg agcttaataa
     1741 cccaatattg atttttccga cggttgcact ggttgtttgt tgaatttcgt cggttgtctg
     1801 gttcaagatc tcgtagatct catgggttga ctttaacatg gtctgaccag cgtcagataa
     1861 atgcagtttc ttcccgacag aataaaacag cggtgccccc accgtccgtt ccaatttctt
     1921 gatctgctgt gttaaggctg gctgggtaat gccaagcaat tgggcggctt gggtgtagtt
     1981 catggtttct gccaattgca gaaaataagt tagtgtcttt gaggaaaaaa tgcgctcttg
     2041 tttcgttttc atagggcggc ttccctttcg tttataattt aataatatcg ttcaaccatc
     2101 atcataagtg gcaatgaaaa aaaacgcaac gaatttgccg cgtttttaat cgttacgtta
     2161 agttctagct aaagattcag ttgctcgcaa ctggtttcgg acgccagctt tgccatccgg
     2221 tataatcctt aacgtgcagc agattctctg cattcttaac gcgatcggca gacggcggtt
     2281 cgatgccttc aagcgggtac gtaatgccaa gctcgtgata ctttttaacg cctaacgtgt
     2341 gatacggaag aatctcaact ttttggacca cgtttttgtc caatgtcgca atatagtccc
     2401 ctaaccgttt gagataaggg tcaaagtcag tgcgttccgg gaccagaacg tggcgaatcc
     2461 acatgtcatc accatgcgcc gacatatact gcaccatatc caaaatattc tcattaggaa
     2521 aaccggtgag ctttttatgc tcggccgaat caatgtgttt aatatcaact aatgagatgt
     2581 cagtaacagc catcagcttt tcaaactggc caaaccacgg ttggtcacgc gtgaaggggc
     2641 cgcctgacgt atcgaggcaa gtcgaaattc ccagtgcctt agccttggtg aagagttcga
     2701 gaatgaaatc gatttgtacc aaactctcac cgccactgca ggtaataccc ccttggtcac
     2761 cccagaatgc tttatagcgc tgggcatccg ccaaaatttg atcggccgtc atttcttcac
     2821 caaccccaat gttccaggtg tcagggttgt gacaatactg gcaacgcatg cgacaccctt
     2881 gcataaagac aacgaagcga ataccagggc catcgaccga accaaaactt tcgaccgagt
     2941 gaacataccc tttgatcggg ccatcatgat cctgaccaac ttgttctaag atatttaatg
     3001 ggctttgtga ctgatcgatg agtttcatct tattgcctcc actacaacat catgtgtcgt
     3061 tttcaattga ttttcatttc attctgccaa aaaacggcaa cagcatcgtt gccgtctttt
     3121 ggcaaaacag gaatggcttc ctgtcttgag ttaagctgct tacatttctt cgaagaaggt
     3181 ccgagcaatg acatcgtctt gttgttcctt ggtcaaatct gcgaagtaga cgcagtagcc
     3241 agaaacccga acggtcaatg ttgggtattc ttctgggtgc ttctgagcat caatcaaggt
     3301 ctccttgttg aagacgttga tgttcaaatg catgccgctg ttttccatat agccgtcaac
     3361 catgtgaacc aaggtatcct tacgagtttc atcatcgtgg cccagtgtgt tcggagtaac
     3421 cccaaacgta ttactaatgc cgtcagttgc gtaatgatac ggaatcttgg cggtggacat
     3481 cagggatgcc agtgcgccgt tcttttctgc gccatatgcc gggttggcac ctggtgagaa
     3541 tggttcgcct ttttgacgac cgtttggtgt tgtccctgta ttcttaccat aaaccacgtt
     3601 ggaagtaatg gtcaggacac tggtgctcaa cttcgcgccg cgatacagat gatgcgtgtt
     3661 catcttgtta tagaaggtct taaccaacca cttagcgatg tcatcagcgc gatcatcgtt
     3721 gttaccataa cgtggatagt catcattgtc agcaacgaag tcaactgcaa caccgttttc
     3781 atcgcgaatt gccttgacat gaccatactt gattgcactg atggaatcaa ccgcgtgtga
     3841 caggccggaa atcccggttg cgaaggtccg gttcagttgg gtatccttca atgccagctg
     3901 tgcagcttca taataatact tgtcatgcat atagtgaatc acattcaaag cattgacata
     3961 cgtgtcggcc agccagtcca tcatcttgtc gaacttattc atgaattctt tgtaatcaat
     4021 gtaatcgctg gtgatcggtg catattcagg ccctacttgc gcttcctgaa tttcatcttt
     4081 cccaccgttg atcgcataca gaactgtctt agctaagtta gcacgggcac caaagtattg
     4141 aacgccatca gcaattggtt gtgccgagac acagcaagca ataccgtagt aatcggtacc
     4201 ccattcgttg cgcatcaggt catcattttc atattgaatg gttgaacttt ggatggatac
     4261 ttcggttgca tagcgtttaa agccttctgg caagcgttcg ctccaaagca aggtgatgtt
     4321 tggttctggt gctgcgccca tgttgtccaa agtcttcagg aaacggaaag ccgtcttggt
     4381 aacgtggtga cggccatcat tgcccattcc tgccaatgac aaggttgccc agattggatc
     4441 gcctgagaac agtgagttat attcttcagt ccggatgaaa cgaaccatcc gcaatttcat
     4501 aaccaaatga tcaatcagtt cctgtgcctg ttcttcgttc aatttgccta agcgcatatc
     4561 gcgttggata taagcatcaa taaccgtatc gatccggcca acggacattg cggcaccgtt
     4621 ttgagtctta acagcagcca gatagccaaa gtagatccac tgaacagctt cttgcgcatt
     4681 agctgccgga cgcgagatgt catagccata ttccttggcc atcttcttca tgtcgtttaa
     4741 ggcacgatat tgttcattga tttcttcacg caatttgatt acatcgtcag tcatttcgcc
     4801 gtcgccggtc aagttataat ccttgaactt ctcagccatt aaacgatcga tcccgtaaac
     4861 agcgatccgt gggaaatcag aaacaatccg gccgcggccg tatgcgtctg gcaagccagt
     4921 cacgatcttg taatggcgag cctttcgcat atcaggggta taagcatcaa agacaccttg
     4981 gttatgggtc ttacgatatt cattgaaaat cttgtgttct tgaggatctg tcttgaagcc
     5041 ataagattcc aatgcatctt cagccattcg aataccgcca aatggcatga atgctcgttt
     5101 gaatggcttg tcggtctgaa caccaacaat cttttcaaga tctttgttca aataaccagg
     5161 gccatgtgag gtgatcgtag atggaatatt gttgtcagca tccaaaacac cgccatttgc
     5221 acgttcttgc ttctttaaat ttagaacctg attgttcagg actgttgtcg cttcagtggg
     5281 gccagcaagg aaactttcgt ccccgtcata ttggttcagg ttatgctcga taaaatcgcg
     5341 cacattaatt tcttcttgcc agtcgccgcc gttaaagcct tcccaataat taggaacttt
     5401 ggtttcgtca agctgtttca tagttgtttg cctcctaaag tggattacag atgtgacagt
     5461 tcttacaaac acagtataac acgccgccaa atctatgcaa gcgttttatt gcccatataa
     5521 taggcgttat attgtttttt aagtgtgctt cgtcgcttct tttcgcccat gatttcggca
     5581 ttttgttaaa ttgtgcacaa ctggtctgtc ctataataat caaaaacgcc accatctgta
     5641 ttagtacaga cggcggtgtc aatgatcacc atttattcga cttgatctgc tggttcttct
     5701 ttggtttgaa caaaaactgg cttgccaagg acatcagtgt caatgacaaa cgaaccattc
     5761 gaatagcggt cacctgctgg atgttgtgcc ggattaaggg tcgttacctt acccgtatcg
     5821 gtcaaaacat tcaggcgggt agcgtcatcg actgacatca tcgcgacaat ccgatgcgga
     5881 tcacgcttaa gctcacgcaa gaccagtaaa ccacgacggg cacgactcat ttccccgact
     5941 tcgcttaagg ccatcttttt gaaggcgcca cgttgggtca aaataccgac cttagccgta
     6001 gttggatcct tcactagaat gaaattgaca acctcatcgt ctggctttag atccatactt
     6061 ttaacgccgg ttgcccgggc accgacagtt gacacatcgc ttaacgggaa tgtcagtccg
     6121 taagcgtggc ggctgaccac aaagacatcc tgttgctgat cagtcgtgaa gtatgcattg
     6181 gtgacaatcg cggctgggtc tttcagcttc atcgccatca tcggcttact cttgtacgtc
     6241 cgttgcggct gcaaatcact taaggcagtt tgtttgatgt acccgtcact tgaccctaac
     6301 acaaaactgc cagcgccatc gagttgatca aaagcaaaca ctgccaagac tttttcgtca
     6361 gtgccaaggc caactgtttg gcttaagtgt tcgccggtgt ctttccaacg cgcatcacta
     6421 atttcatgca ctggtcgata aatgacattt ccggcatttg tcacgatgta aagatgctgc
     6481 aacgtactca gttcgccagt gaaaatggca agatcattgg ccttcaaacc attgtcggcc
     6541 ggatcaaccg cctgataact gcgcagtgaa ctgcgtttaa cgtacccatc acgagaaacc
     6601 tgcaccatga cggtttcatc agccaccgtc accgttgtcg ccacttcaag tgtttcaatt
     6661 ttggcttgaa tgctgctgcg acgatcatcc ccgtactcct tggcaatccg cttcaactcg
     6721 ccttcaatca cccgatcgcg ggcagcgggg cgggccaaaa tatcttgata ctcggcgatt
     6781 gctttcgcca attgtgctgc ttctttctgt aaagccgtga tatcggtatt ggtcaatcga
     6841 tacagctgca aggaaacaat cgcttccgcc tgagcttccg aaaaatcaaa cttcttgact
     6901 aagttacgct tagcatcccc tttatccttg gaagcacgaa tcgcggcgat gacctgatcc
     6961 aaaatcgata gcattttgat caagccttcg acaatgtgct gtcgagcagc ggccttgttg
     7021 aggtcaaaac gcgttcgccg agtgaccaca tcgcgtcgat gttcgacgta tgcttccaac
     7081 atggccttaa gtcctagcaa cttcggctgc atgtcggcaa tagcgaccat gttaaagttg
     7141 tatgcaattt gtagatcggt atttttaaat aaatagttta agatgccatg tgcatcggct
     7201 tcttttttta attcgatgac aacgctaagc ccaaaacggt cgctttcgtc acggacttcg
     7261 gcgataccgt ccactttttt gttgatgcgt aattcatcga tttttttaat catctgcgct
     7321 ttattgacat catacgggat ctcagtgacc acgatcttct cacgaccgcc acgaatggtt
     7381 tcgatgtgtg tccgagaacg aaccacgatt ttaccgcggc cggtttcgta agcttgcttg
     7441 atgccatcaa gcccttgaat aatcccacct gttggaaaat cgggaccctt gacgtattgc
     7501 attaaagtat ctaaatcagc agtgggatgc ttcagcaagt ataagacggc agcaataact
     7561 tcccgcagat tgtgcggcgg aatttcggtt gcataaccgg cagaaatacc ggtggcaccg
     7621 ttcaccagca aatttggaaa cccagctggc agcacagtcg gttcctgtgc cgtgtcatca
     7681 aagttcaaca ccatatcgac ggtttcctta tcgatgtcgg ccagcatttc cttgctgatt
     7741 ttgcttaaac gcgcttccgt gtatcgcatt gcagctggcg gatcaccatc catggaaccg
     7801 ttattcccgt gcatctgaat cagtggggcc cgtaacttcc aatcctggct tagccgaacc
     7861 atcgcttcat aaatggagct gtcgccgtgg ggatgataat tacccatgac attcccgaca
     7921 cttttagccg acttgcggaa gcccttatca tacgtattgc catcttggtt catcgcaaat
     7981 aaaatgcgac gctgaaccgg tttgaggccg tcacgcacat caggcagcgc ccgttcttga
     8041 ataatgtatt tcgagtaccg gccaaaccgg tcgcccatga cctcttctaa ggtcagttct
     8101 tgaatctgat tggccaatgg cttttacttt cctttcttgt ccagttgttt gacgatttgc
     8161 ttggcaccaa actgtaattt ttcgtgatta gcagtcgggg tttccaaaat actgccgtcg
     8221 tcatccatat caaacttgac gttatgctca atccattcac gacgcggctc aacgcgatca
     8281 cccatcaaag tggtcacgcg tcgttccgcc agctgagcat cgtcaatccg aacccggatc
     8341 aaagtccgcg tctcaggatt catagtcgtt tcccaaagct ggtcggcatt catttcccca
     8401 agtcctttaa atcgggtcaa tgtgtaaccc ttgcccatgg ccttggtctc tttggccaac
     8461 tcttcatcgg tccaagcata actgatcttg gttttagcac cagcgccttt ttgcagccga
     8521 tacaatggtg gcaaagcaat gtaaattcgg cctgcgtcaa tcagcggccg catgtagcga
     8581 taaaagaagg ttagtagcaa aatctgaata tgcgcgccat cagtatccgc atcagtcata
     8641 ataatgattt tgtcgtagtt ggcctgctgc agatcaaaat ccgcaccgac accagcgccg
     8701 atggtgtaaa tcatcgtatt gatttcttcg tttttaacga tgtcctgtaa cttggccttc
     8761 tgggtattca gtactttccc tcgcaatggc aagatcgcct gaaactttcg gtctcggcct
     8821 tgtttagctg aaccaccggc agaatcccct tcgacgagat acaattcgtt acgcttaggg
     8881 ttcttggttt gcgccggggt caatttaccg gaaagcaaac cttggtcctt cttgcgcttg
     8941 cgtcccgtcc ggctatcgtc gcgcgctttt cgagccgctt cccgcgcatc acgggctttg
     9001 acggctttac gaaccaactc ttgcgactct tcaccgtttt ccatcaaaaa agttgacagc
     9061 ttgtcataga caatcccatc gaccacagtg cgggcttgcg gcgtacctag cttgcccttt
     9121 gtctggccct caaattgcaa aatttcttct ggaatgcgga cacttaaaat acctgcaaaa
     9181 ccttcacgca catcactgcc ttcaaggttc ttgtcgcgtt ccctcagcaa gccgactttt
     9241 cgggcaaatt cattgaatgc tcgcgtcatg ccgctgcgca agccaatttc atgcgtcccg
     9301 ccatcaccag tgcgaacgtt attaacaaac gaaatcaggt tttcagaata gccatcgtta
     9361 tattggccgg caaaatcaac cacgataccg tcctttttgc cttcaaaatt gatcacctgt
     9421 gacaatgcgt ctttgccttc attaaggtat ttaacaaaac tgaccaagcc atcaggatag
     9481 tgataactgt cgtgcttacc ggtgcgttca tccgtcagat taatcgtaat atttttcagt
     9541 agaaaggctg attcgcgcaa gcgttcggcc aaggtatcat aactgaagac ggtggtttga
     9601 aaaatagtcg ggtccggctt gaatgtgatg gtcgtgccat taggttcatt aactttgccc
     9661 aacttctgca aactgccatc aggatgaccg ccattgataa aatgctcctc aaatgcgtgt
     9721 ttatcccgca caactcgcac agtcaatgac tccgataggg cattgacgac gcttgagcca
     9781 accccatgca aaccaccaga agttttgtaa ctattttggt taaattttcc gccggcatgt
     9841 agcacggtta aaatgacttc aatcgtcggt ttaccactcg ggtgcatccc cgttggcatc
     9901 cctcgaccat gatcctgtac ggtcacagag ttatcggcgt gaatcgtcac attgatctca
     9961 tccccaaacc ccgcgagcgc ttcatcgaca gagttgtcca cgatttcata gaccaagtga
    10021 tgcaaaccgc ggccatcggt ggaaccaata tacatccccg gacgcttccg cacagcttcc
    10081 aagccatgca gcacctgaat ggatgaatca ttatatgctt gcgttgcttt atccatagta
    10141 aactcccttt tttgaacaac taagttatag aatacaccac gcgttgagat ttcagaaata
    10201 aaaaataaga gcgcgagcca gcccgattag aaaccggagc ataggcggcc ttgggtgcga
    10261 tggttgggct ttgacgattg tgcccaaggt ccttatgtgt aggtttctgg gctggcgagc
    10321 gcgtttcagt agagcgcgag caggagcggt tagcaaccgg agtgtaagcg gccttggacg
    10381 tgatggtcgg ctttgaccat tgcggccaag tcccttacac gcaggttgct gcgactgcga
    10441 gcgcgtttca atagagcagc ccgattagaa accggagcat aagcggcctt gggtgcgatg
    10501 gttggacttt gaccattgca cccaaggtcc ttacacgcag gttgctgcga gtgcgtttag
    10561 gcatcaacac catcaacagc agacctcaac gtattgctct caggactcct gttttctcct
    10621 caaaatcgac ccagctggct aataccatca ttgttcattt aaattttatt agccgtgtca
    10681 atgtcccaaa gctcagcaga aaaccgcact tccctaagca tggcacataa ctatgacttc
    10741 ttgacgtgaa attcatcgcc cgctggcacc atatctacgc tgtgccccgc catgatcctt
    10801 gcgcaagaca acaccaaatc gcgccacaac ccgcttcaca ggttttattc gaatgtacgt
    10861 tcgttttatt ctactgacgt atcactcaaa agtcaaaaat gctaaaatag tttctagttt
    10921 gagaggaggg gcacatttga tacttgtgct ttgttttata ctcgcgtatt tcataggcgc
    10981 catcccgttt ggtgtggtca ttggtaaact cttttatcac acggatatcc gcaaaggcgg
    11041 gagtcacaat attggcacca caaatgccta tcgcatgtta gggccagtcg gcggctcaat
    11101 tgtcttggtg ctggatatct taaaaggcac gttggctgcc agcttaccca ttctctttgg
    11161 catcgagcat cattggctgg tgctgatcgt gggtttagcg gccgtattcg gtcatacatt
    11221 ttcgatctac attcgcttta aaggcggtaa ggcggtggca actagcgctg gcattttact
    11281 tgcatataat ccgccatttt ttgtcattgc atttgccatc tggttcagtt tgatcttgct
    11341 aacgtccatg gtcagcgttg ccagcacact gggtatggtg ttgatcacag cttggtcgct
    11401 tgtttaccat gattggttgc tgacaactgt tgcctgcggg ttgctggttg tctttttgat
    11461 caaacatcgg gcaaacttca aacgcatcaa ggccggagat gaaaatatgg tgccctttgg
    11521 cttaggccaa tatcttcgtc aacaccgggg ccgctcttag tcaccttttg atggcaacca
    11581 aaaagacatc cgaaactgga tgtctttttt tcatgtacct aatcgacaaa ctgatgacac
    11641 cttagaaaat gctgatcatg taacccttct caaatgccgt gccaggttca agtcgattga
    11701 tcccgagttt gcgcgtcagg tcgccagtgc tgccaatcgt gtcggcgatg ccccaccaag
    11761 gttcgatgca gacaaagtcg ccagtggttg gatacggact ccaaacgccc agatatgggg
    11821 tatcggtcat ggtaacgctg acaccatgtt tcgtcttgtc agaaaccaag ttgaaggttg
    11881 tcttaccaag caacgcgaaa attaaagcat catgatcaaa tgtttcgtgc gttaaggcca
    11941 aattggcatc agttgcagcc aaggtccggt gcgtgtaatc aatgccttca ccagcaacca
    12001 atggaatctg aacaagcgac ttacgcggtt tgaagttcaa ataataatcg gagaattgag
    12061 tatccggcgt cattgggacc ttgaagcccg gatggccgcc gatgctaaag aacagtggct
    12121 cacttttgtc cggattgtca acgtgatacg tgacatgtag attgttattt tctagtgcaa
    12181 acgtgatgat taaacgaaaa gcgaacgggt acatcgcccg cgttttgtca tcatccttca
    12241 gaacgaagct cgctttaaac ggtgtcgcag agagcaccgt gaaatcacga tcacgggcaa
    12301 aaccgtgctg gcccatgtgg taagtcttgc ctgcgtaatg atattgattg tcagccagcg
    12361 ccccaacaat cgggaacaag accggggcgt ggcgacccca caccgcagga tctgcttgcc
    12421 acagacgctc cctgcctgtc aggttatctt tgatactggt cagttcagca ccatgccgac
    12481 tgattttaac tgtcaaaaag tcatttgcaa tcgttaccat acatcctcat cctttaccta
    12541 caacattatt gttaactaca aaatataccg cgtcatgttt gaatcagccg caatatggcc
    12601 aatcttgtca tccacatatt gctgggtgac ggtcacactg cccatcgcca tatctggacc
    12661 ttcataaagt acgtcttcaa gcagtttttc aagaatggtt gccagtcgcc gcgctccaat
    12721 attatcagtg tcgtggttga cctgagtcgc aatctctgca attcgatcaa ccgcttcctt
    12781 cgtgaaggta atcttcacgc catctgcacc aatcaaggcg atatactgct tgatcaaagc
    12841 attgtctggc tcggtcaaga tccgcacaaa gtctttttcg gttaagtcct tcaattcaac
    12901 ccgaattgga aaacgccctt gaagttcagc aatcaaatca ctaggcttag cctcggcaaa
    12961 cgcacctgag ccaatgaaca agatgtgatc cgtattgata ggaccatact tagtgttaat
    13021 ctgcgatcct tctacaatcg gtaaaatatc tcgctgcaca ccttcacgcg aaacttcgcc
    13081 gctattatgc ttgtttcctg cagcaatttt atcgatttca tcgatgaaaa tgatcccgtt
    13141 attctcggca ctttgaatgg cgtcgtgata aatgtcggca tgattgacca gtttgtcaga
    13201 ttcctctttg atgaagattt cgcgagcttc tttgacggtc atggtccgct caaccttttt
    13261 cttaggcatt aaagcgccaa tagtgtcgct tagatcaatg cccatctgac cgtacatgtc
    13321 acccatgcca ccgccttttt tctcatcatt gacagcaacg gtgatttcat gatcttcaag
    13381 taatcctttt tccagttgct ctgccacgct caaacgctta ttgcgaatat catcggtcac
    13441 ttcgccgcct gcatctgcat catcgccagc tggcattttg ccattttgca tcccttgcaa
    13501 catgctcatc atctcggcca tcggattggt attcttttcc ttacgaatgg ccggcactaa
    13561 aattttaacc aaacgcttgt tggcttcttt ttcggcacgt atgcgaacct ttgaaaattg
    13621 cttctcttct tccatggcaa cggcagtttc ggcaagatct cggaccatgg attcgacatc
    13681 acggccaacg tagccaactt ccgtaaactt agtcgcttcc accttcacaa atggcgcctc
    13741 aactattttc gccagtcgtc gtgcaatttc ggttttcccg acaccggttg gtccgatcat
    13801 cagtaagttt ttcggggtaa tctcttcttg catttttggc gataattgca ttcgccgata
    13861 acggttatac aaggcaaccg cgacggcccg ttttgcatca tcttgtccaa tgacatattg
    13921 atcgagtttt tcaacgatct gttttggggt ttgtacttct gccatcataa gcctcctgta
    13981 ggtcaatgta attgccgacg gttacaaact aaaagctttc gacaataaca ttgtggtttg
    14041 tgaaaatatc gatattccct gcgatattca ctgcttcttt ggcaatgtca gctggtgtca
    14101 tatctggggc atgccgcagc atcgcgattg ccgcggcttg cgcaaagttg ccgccggagc
    14161 cgatcgctac cacgtcttca tctggatcta tcacttcgcc agacccggat acaagtaaca
    14221 ggtcatgctc atccatcacg atcatcatgg cttcaagttt ctgcaaggtc ggatccttgc
    14281 gccaatcttg agccagcgca actgcggaac gtcgcaagtt gccagcataa tgctccagct
    14341 tcttttcaaa ccagtcttgc agggtgaaag catctgccac cccgccggca aatccgatga
    14401 cgacttgatc atgatagatc cggcgaactt tctgcgcgtt gcctttcatg atgacctttt
    14461 cgccaagggt tacctgaccg tcaccggcca aagcggtcac accatctttt cttactgctg
    14521 caattgttgt catagtcatg ctccttttta agtgagcgcg agcagaagcg cttagaaacc
    14581 ggagcataag tgggctgcaa gcctaaatgg ctgaattttg gctatttagg cttgcaggtc
    14641 attatgtgta ggtttctgcg actgcgagcg cgttatctgc gtatctcgtc ggataaaaac
    14701 agctaaagta gcgattaatc tgttatcgcc aatgttctta gcttaaaaaa ctcagactgc
    14761 ttttgcatca tgctttagtc ttaattatgc ttcggataat atttcatata ctcatttttt
    14821 aaatgtgcca tggtgacatg cgtgtagatt tgtgtggttg ataaacttgc atgacccagt
    14881 agctcttgaa cagttcgcag gtcagcacca tgatccagca tatgggttgc aaaactatgc
    14941 cgcagcatgt ggggatgaat gttagctgtc agcgtcgtct gcttgatgag ctgatccaaa
    15001 atatattcaa tgccacgcga ggtaatcgga cgcccatact ggttcacgaa tacatatcga
    15061 tgctgtgcct gacttttagc catcaagact tgtcggccat cttttaaata agttcgtagt
    15121 gcttgctgag cgtactgtcc aaagggcaca tacctatctt tgttgccttt accatgaatc
    15181 aacagtaatg ccgtattgaa atcgacctga ttcaatgtca gtttggcaca ctcggaaact
    15241 cgaataccgg tgccatacaa aacttccaac aaagcgcgat tacgttgatc cagcggggtt
    15301 ttgccagcaa ctgtcttgaa cagttcctga atctcggctt catagaaaaa ttgtggtaaa
    15361 tgatgatgct gcttttttaa ttcaaccagc tcaaatgggt tgcgtttgac gacatcaatt
    15421 c
//
