LOCUS       gnlProkkaPPOANHPM_20   10518 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPOANHPM_20.
ACCESSION   gnlProkkaPPOANHPM_20
VERSION     gnlProkkaPPOANHPM_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:57:20
            Original ID  :: gnl|Prokka|PPOANHPM_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6712
            Orig. end    :: 17230
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10518
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5518]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5518
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10518
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10518
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(131..1018)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_12"
                     /sec_met_domain="Abi (E-value: 8.6e-12, bitscore: 37.2,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKGHSLTGILFIAMSEKAGFVNLDEGDGMKKKRQRLFTPGLRVL
                     YIFILDELIEAFVFTPFLNFLQLDFWADIVLYKVLSLVIILGLNLLLLRQKIIFRTSFG
                     WPSWQKFVFWDIVGCLVAWQIFTNRNFLDILQASVIGTIAAVPEEYLYRGVIFGGLLRA
                     FYLANRGGTKRNFLYCMLLSSLAFSLAHLSNLPSQGAVATVGQMIQVSGMGMLRAALYV
                     RYGTFLMPIFVHFMIDFLVTLIHGPYPSKLNGVSDETTLITVSLIWATIYLVISMWTLW
                     HCHDKEGFMARLSK"
     CDS             complement(1215..1514)
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="MADRNSLLDRFVANIGTRKCEVGSRVLRCLYCDLPLYLDWLGKEH
                     DEMHRIKNDDLQQMIEGMTWRKFLTMLILGLIAIDAWSHTDQIIAGFLKGWQGV"
     CDS             complement(1489..1785)
                     /locus_tag="ctg20_14"
                     /transl_table=11
                     /translation="MTGLNESFQKTATVSVMNTEAQEVIDDALHILEKENVLQNRAIDY
                     ALARLYSRFVRLIGLQGMKLSPEADQWWQQLKDFMENDIHEELSQVGGPQFIT"
     CDS             complement(2077..2754)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_15"
                     /sec_met_domain="Abi (E-value: 2.1e-18, bitscore: 58.4,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDMKKRGIELGKFAANHSLKGRHQGQRPKKFTVLVFPVCFGMIL
                     PQLLSGILSMIYIRLNQLLALIGWYAFALFFLLKSYDYCWQQGYFKPSYLKLLKGICLG
                     ISLVGFEWIFSTVFPKADGATIDEHAVPIMLLVVCVFAPLWEEVVFRGILNAKIFKKRF
                     VGVLISSILFAVLHGYVSPAMLFYFCLGIAFSLVNRDQTDVFTSVVAHMSFNVIVLILT
                     LSS"
     CDS             complement(2726..2917)
                     /locus_tag="ctg20_16"
                     /transl_table=11
                     /translation="MAMTLNKAIHYLLLIGISGVFLFTLAAAMGWVNQGDFALPLLLLA
                     AGLTLLREADAGYEKARH"
     CDS             complement(3236..3571)
                     /locus_tag="ctg20_17"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSKAYANPTIKAEPALRALIETNAKKVDEGDDDK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAARYRAQALAAGLVA
                     IPIVWGH"
     CDS             complement(3690..4286)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 107.6;
                     E-value: 1.1e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_18"
                     /sec_met_domain="Mac (E-value: 2.4e-10, bitscore: 32.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRKLVGQTGFKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGNHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMI"
     CDS             complement(4557..4865)
                     /locus_tag="ctg20_19"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             complement(5001..5216)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_20"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.6e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(5213..5518)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_21"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.7e-14,
                     bitscore: 44.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVKDSKVDLTQNNLLLFEERRKIISYNYRQLDDFQLSGVSGGKK
                     KFDCAATFVTGITAGIGSGTITGLAGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(5718..6671)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.1; E-value: 7.2e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_22"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVDDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             6876..7610
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 3.9e-12. Score:
                     38.3. Matches aSDomain: nrpspksdomains_ctg20_23_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     193; E-value: 1e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_23"
                     /sec_met_domain="adh_short (E-value: 1.2e-34, bitscore:
                     111.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSATDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        6894..7382
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_23_PKS_KR.1"
                     /evalue="3.90E-12"
                     /label="ctg20_23_PKS_KR.1"
                     /locus_tag="ctg20_23"
                     /protein_end="169"
                     /protein_start="6"
                     /score="38.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       6897..6977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg20_23_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg20_23"
                     /protein_end="34"
                     /protein_start="7"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             7636..8799
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     290.2; E-value: 3.5e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_24"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRNHVDGAFPVIVVGGIKTPADAEKAADFFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
ORIGIN
        1 ttgctgatat cactgtatag gtccaatagg agaatgcctc caatgatcag gcaaatcttg
       61 aatgcttttg ccattcgaat ccttttttcg gttaactaag ctcatcagtc gtgctgttcc
      121 gacataaacc tcattttgac aaccttgcca tgaacccttc tttgtcatga cagtgccata
      181 gggtccacat ggaaatgacc aagtaaatcg tagcccagat caacgaaaca gttatgagtg
      241 tcgtttcgtc acttacccca tttaatttgc tgggataagg gccgtgaatc agcgttacca
      301 agaagtcgat catgaaatgt acaaagatcg gcatcagaaa tgtgccataa cgaacgtaga
      361 gagcagcccg cagcatgccc atcccgctga cttgaatcat ctgacccaca gttgcaacag
      421 caccttggct tggcagatta ctcaagtgtg caagcgaaaa cgccagactg cttagtaaca
      481 tgcaatagag aaagttacgt ttggtaccac cacggttagc aaggtaaaag gcgcggagca
      541 agccaccgaa aataaccccg cggtataggt actcttcagg aacagcggcg atggtaccaa
      601 tgacacttgc ttgtaaaata tctaagaagt ttcggttggt aaagatttgc caagccacaa
      661 ggcagcccac aatatcccag aacacaaatt tctgccagct tggccagcca aatgacgtcc
      721 taaagataat cttttgtctt aacagcaaca gattgagccc cagaatgata actaaactaa
      781 gtactttata gagcacaatg tctgcccaaa aatccagctg tagaaaattc aaaaatgggg
      841 tgaacacaaa tgcttctata agttcatcca agataaaaat gtataaaaca cgtaacccag
      901 gcgtgaacaa ccgttgccgt ttctttttca ttccgtcacc ttcatccaag ttgacaaagc
      961 cggctttttc cgacattgct atgaacaata taccggttaa tgaatggcct ttagtcaact
     1021 aattttaaac gtcgtgtttt caccacttaa cgttgacgat catccgtcaa aaattcgcta
     1081 gcggtcattt attgacaaaa aaagccactt cactcggcaa acgacgctac gctaagccaa
     1141 gaagaagtga cgctgcagtg ttgaaaaagt tgcggagctt gcaattggcg caattcttca
     1201 ccggtcacaa acacctacac gccctgccat ccctttaaaa accccgcaat aatttggtca
     1261 gtgtgtgacc aagcatctat cgcaatcaat cctaaaatca gcattgtcag gaatttacgc
     1321 caggtcatcc cttcaatcat ttgttgcaaa tcatcattct ttattcgatg catctcatcg
     1381 tgctccttcc ccaaccagtc taaataaagt ggtaagtcac agtataaaca gcgtaacact
     1441 cgacttccga cttcgcattt gcgtgtgcca atattggcaa caaaccgatc aagtaatgaa
     1501 ttgcggtccg ccaacctgac tcagctcttc atgaatatca ttctccatga aatctttcag
     1561 ttgttgccac cactggtcag cttctgggga taatttcatc ccctgcaggc caattaagcg
     1621 aacgaaccga gaatacagcc gcgctaatgc gtagtcaatg gctctgtttt gaagcacatt
     1681 ttctttttcc agaatgtgta gtgcatcatc aatgacctct tgcgcctcgg tattcatgac
     1741 actgacggtt gcagtttttt gaaagctttc gttgagccct gtcataataa aatagacttt
     1801 atttcgctga atcatgttca taatatgtca ccatttcctt tgatgtcgtg acaatttttc
     1861 cgtagaaaag tttgagaaat atcgatctta tgagttttaa gcaaaatact gaagaagcaa
     1921 cgtctttaac tcaacaagcg gctattaata ccgctttata cttgaactca tgcgcatata
     1981 aatcaatatt gtaatcggtg acattttaaa gtcagtttgt gcttgtgtac agaaatgcag
     2041 cttctggttt atgcattgag taaactggcc aattggctaa ctagaaagag tcaaaattag
     2101 cactattacg ttaaaactca tgtgtgcgac aactgaggtg aagacatcag tttgatctcg
     2161 attaaccaaa ctgaatgcaa tgcctaaaca gaagtaaaaa agcattgcag gtgaaacata
     2221 cccatgcaag actgcaaaga ggattgacga tataagcacg ccaacgaacc gctttttgaa
     2281 aatttttgca ttcaaaatac ctctaaaaac aacttcttcc cataacggcg caaatacaca
     2341 gaccaccagc aacatgattg gcacagcgtg ttcgtcaatc gttgcaccgt cagcttttgg
     2401 aaagacggtc gaaaaaatcc attcgaaacc gaccagcgaa attcctaagc atatcccctt
     2461 aagtagcttg agataggatg gtttgaagta cccttgttgc cagcagtaat cataagactt
     2521 cagcaaaaag aagagcgcaa atgcatacca gccgataagt gcaagcagct gattcaatcg
     2581 aatataaatc atcgaaagaa tacctgaaag aagttgtggc agaatcatgc caaaacacac
     2641 gggaaacact agaacagtga actttttggg tctttgtcct tgatgacgcc cttttaatga
     2701 atggttagcg gcaaacttgc ccaattcaat gcctcgcttt ttcatatccg gcatcagctt
     2761 cccgcaacaa cgtgagtcct gccgccaaaa gcagtagtgg cagcgcaaag tcaccttggt
     2821 tgacccagcc catggcggca gccagcgtaa aaagaaagac accactgatg cctatcagta
     2881 aaagataatg aattgcttta ttcaacgtca tcgccaactt gtatcccccc gtccagatga
     2941 acttcgactt tttctcgcgg atgcttttac gcacactata ctggatagtt cacacaacag
     3001 cgcaaacttt ttttaaacgt agggttttgc ccgattaacg tcgctttttt gtcaaatatc
     3061 gaccaaattt tctctttatc gatctgctac tcggtttttc ttaactggtg tcaacaagtt
     3121 tcatggcaaa aaaatagccg cagatcttag tctgcgacgt ttttttgcaa atgataactg
     3181 attgcttgat catcaacttt agcctcaccg tttagaattc acagttgtac atcggctaat
     3241 gcccccaaac aatgggaatg gcgactaagc cagcggccaa ggcttgcgcg cgataacgtg
     3301 ctgcatcaat atcggcagca ggtacatctt ttttgatgta attgaagacg gccaccagct
     3361 cttctggtac ggcgtgatga atcagatagt atttggaaat gtcgtgggac aactgagtga
     3421 cagccgtcac ataagcctta tcgtcatcac cttcatcaac ctttttggcg ttggtttcga
     3481 taagcgcccg taatgccggc tctgctttga tcgttgggtt agcgtatgcc ttgcttagca
     3541 ttgacattaa agtttcacgt ttatctgtca tcctgcactt cctttcgatg attaacttgg
     3601 caattcatgc tcactcagag cactttagtc attgtgaata ttgttagaat gcgcttgtca
     3661 attgccattt tcaagtatcg atttggcgtt tagatcatgt catgccctgc aaaccctgtt
     3721 ttatcagcag ccgtgatctc gcggagcact tcgcaaggat tacccgccgc aatcacgcga
     3781 gctgggatgt cgtgggtgac aacactacct gctccgataa tcgtccccgc accaatcgtg
     3841 acgcctggta gtaccgtcac attggcagcg agccaacagc catccccgac tacaatcggt
     3901 ttagcaatac agccaccaag ttgtcgttca agcggatcaa aaagatggtt gctggtgtac
     3961 aaaccgactt tcgggccaaa caaaacgtga ttgccaatgg tcaccggcgc cccgtccaaa
     4021 atggtacagt cataattggc ataaaaatga tcgcctacgc ggatattccg accaaattca
     4081 cagtgaaagt ttgggttcac aaacggtttg aagccagttt ggcctaccaa tttcctaaac
     4141 aaggcattgc gtttggctgg atcgtgttca ttgttaagtg catcagtttt ggcagttgct
     4201 tcatcccgca cagccagtaa caaaggatcc atgtcgtcgt atggcttacc agttgccatg
     4261 aaagcaaatt tttcttctag attcattgcg ccacccctct ttcttggctc aagtttacca
     4321 gacatttgcg cactgcgttg ataattgcca atatgttaag gtgtgcttat cggtacgcat
     4381 gaagtctaca aaaagccacc acttcttgaa gaaatggtgg cttgaaaaca atgacatcgc
     4441 ttctgcacac agaaccacgc ctgttttgtt acaaacagaa acatacagtt acagtcttca
     4501 tcgtcacaaa attctggcgt taggaaattt cagctacttc ctcggacttt atcagcttaa
     4561 tccatagact taatctcaag tgacattaac tcagatttta gcttttttaa atttgacata
     4621 gagataaatg taaagtcaag tcttccatct agagtagtga gaactatata agggttctgg
     4681 ggattgatta acctactcag ccccttacta gatagtttca aatcccgatt taacaaaagt
     4741 atcttggcaa tgactttgct tcttgctgcc ccttgccaaa gtcctccaac aaatggtgct
     4801 agataaaaag cgatcgtcgc cagtaaaatc aagataacta tgatgatact tattatctta
     4861 tccatttgta tttcctcttc cttttgcaca aatagactaa tttgaaatcg atctttgact
     4921 aagacaagaa aaagtgagca ctaccaaggt gttagttata ttgaacagtt gcgataggag
     4981 ctaaccgtct ttgtccaata ttaggctggg tgaatgtaat tagtgctgag acacaaggat
     5041 aatcctattg cagcgcctgc aacagttgta aatggattta atccagctgc ccctgctacc
     5101 gctcccccga tcgtggacac aatacaccca ctaggtttat tgcgtcgctt ggctcctcct
     5161 tggattaaga ccaaatcatg ctgttttaaa gtaatgccca cttctttact tatcattgca
     5221 tcccatctcc taagcattta atagctgacc caaccgctcc taagtttcca ccaactacgg
     5281 cgccgccgat tatcccaaaa ggaccaccag ctaggccagt aatcgttcct gatccaatac
     5341 cagccgtgat gccagtaaca aatgtagcag cacaatcaaa tttctttttc ccacctgaaa
     5401 cccctgacaa ctgaaaatcg tcgagctggc gataattata agatataatt ttccttcttt
     5461 cttcaaaaag caacaagtta ttttgtgtaa ggtcgacttt actgtcttta acatacatta
     5521 attatttgtg taaaatgcca aaatttttta aacgtaggaa atttccagtt taacgtcgtc
     5581 tttacacttt tattgttcag ttgcgcttta aaagtcaaaa attcttaacg tttaaatctc
     5641 cttgcttggt aaaaacttca attttttgca aaaaaaatcg tctcagcaat ttgagacaat
     5701 tttttcatat catcaactta cggcaaatca ttccccgccg caaagtaaat gtcataccat
     5761 tcttgtcggg tcaacgtgat gtccgcgcct tccgcacttt ccttgatatg ttcaggattc
     5821 atagagccga gaatcacctg cacaccaact ggatggcgta atagccaagc gactgcgatt
     5881 gcatttttat tggtgtggta gtggtcagcg actttctgca gttcatcatt caacgcctta
     5941 aacttcgggc tatcgataaa ggtgccttca aacatgccgt attggaatgg tgaccatgct
     6001 tgtaaggtca tgtgtttgcg ttgcaagtat ggtaataggc tgccatcatg atcgaccgag
     6061 gcagcgtcgg ccatgttggt gtgcatcccc gcattgacca tgccagtatg ggcaacggag
     6121 aattgaactt ggtcaatcag caaaggctgc cgaatgccgc tttcaagcaa cgcaatttgt
     6181 tcagggttaa agttggagac gccaaaatgc cgaaccttgc cactttgttc caatgcatca
     6241 aaggccgccg caacgtcatc gacttccatt aacggatctg gccgatgcag caagaccgaa
     6301 tcaaggtaat caacctgcaa ccgtttcaaa atgtgatcaa ccgctgacag taagtgatct
     6361 tttgaaaagt cgtaccgttt gccgaatacc aaactgccat gagagcgttt tggatcatcg
     6421 acgatcccga ctttcgattg aatgaataac tgatcgcggg aaacgctggc ttgcttcaag
     6481 gcttcaccaa aaacttcttc ggatttgcct tggccataaa tgtcggccga gtcgataaag
     6541 ttgatgccgt cattgtacgc actatccagc acattggccg ctttgtcggg ggccagcaca
     6601 ttcatccgca tgatgcccaa ggccacactt gacgcctgcc aattggatcc gcctaatcga
     6661 acttgtttca taaacacaaa actcccttcg atacgtcatt tcaaattatg ttactgacga
     6721 caagttaagt gtagccccta aagtccactt gaggtcaagc caatattaga atttcaataa
     6781 aacagcttgc atggtgctga gctgcgcggt aggttaagct gtgtctgtta cttatttttt
     6841 cttagcagga taagcccata aaggaggccg tgattttgac agttaaagat aaagtggttg
     6901 taatcacagg tgcatcaagc gggattggcg cggcaacggt acaagtgctg gccgaggctg
     6961 gtgcaaaact agtcatcggt gcgcggcgca cagaacggtt ggccgaattg gcggccagct
     7021 ttacggacgg tcaggtgctt tatcaacaaa ccgatgtgac cgaccagcag caagtgaaag
     7081 cgctgattga tttggcgttg gataagtttg gtcatgtgga tgttttgtat aacaacgctg
     7141 gcctgatgcc actttctgaa atggccgaac tcaaagtcaa cgaatgggaa cgtatgattg
     7201 acgtcaacat taaaggcgtc ttgtatggga tcgccgcggt tttaccgcct atgattgccc
     7261 aacacagtgg ccaaattatc acaacagact cggtcgccgg tcacattgtt caccctggaa
     7321 ccgccgttta ctccggtacc aagtgggcta tccaggcgat catggacggc ctgcgacaag
     7381 aacaagcagc taatcatatt aaaacgacca tgatctcgcc cggtgccgtg aatactgagc
     7441 ttttcagcac aattaccgat cctaagcgcc gtgaagctgt tgaagccgat gaaaagaaca
     7501 atggcctcag tgccacggat gttgccaagg cagttttgta tgccattgat caaccggcca
     7561 atgttgccat caatgaagtg ctcttacggc cagtcacgca agaacgttaa ttttcgtcta
     7621 aaggagtgtg attgcatgtc gggttatcat tttttaaaac cgttcacctt caagcaccaa
     7681 accatcacgt tgaaaaatcg cattgtcatt ccgccgatga caacgcgcct gtcgtttgaa
     7741 gacggcactg tgacgcggga cgaaatcagg tattaccagc aacgggccgg tggcgtcggc
     7801 atgtttatta ccggtaccgc caatgtcaat gcgcttggca aaggattcga aggtgagcta
     7861 agtgtcgctg atgatcgatt catccccggt ttgagcaaac tcgccgctgc gatgaaaaca
     7921 ggcggcacca aggctatttt gcaaatcttc agcgctggcc gcatgagcaa tagcaagatt
     7981 ctgcgcggtg agcagccagt cagtgccagt gcggttgctg cgccacgggc gggttacgaa
     8041 acaccgcgcg cattgacatc ggcagaaatc gaggcaacta ttcacgattt tggtcaggct
     8101 gtgcgccgcg ccatccttgc tggttttgat ggcatcgaac tgcatggtgc caacacctat
     8161 ctgatacagc aattctattc gccaaactct aatcgccgaa ccgatgaatg gggcggtgac
     8221 cgcgataagc ggatgcgttt tccgttggca gtcgttcatg aagcagaaaa agtgattgcc
     8281 acaattgctg accggccatt tttgttaggc taccgcattt cgccggaaga gttggaacag
     8341 cctggcatta ccttggatga taccttggcc ttaatcgacg ctttgaaaca aaccaagatt
     8401 gattacctgc acgtctccca aagtgacgtt tggcgaacct cattgcgcaa ccctgaggac
     8461 acagccatca tgaatgaaca aattcgtaac cacgtcgacg gtgcttttcc agtgattgtg
     8521 gtcggtggca ttaaaacccc cgccgatgct gagaaagcgg cagatttctt tgatttggtc
     8581 gccattggtc acgagatgat tcgcgagccg cactgggttc agaaggtctt agaccatgac
     8641 gaaaaggcga tccgttacca gatcgcccct gctgatcttg aagaacttgg cattgcgccg
     8701 accttcctcg attttatcga aagtatttcc ggtggggcaa aaggtgtccc gttaacaact
     8761 gcgcagtcta tgacatcaag caacgtgcct caagattaat ctagcatttc aaatcatcgt
     8821 gcgagttgag ctgtaaaaag ctcggctttt ttcttgccgt cttcgactta cgcgatggtg
     8881 cctggagcta ccagtgattt ataagtttta aatcaaggtg tgatcatcac ctactcacgc
     8941 tctgacttaa acgcgttcgc cagcgcagaa acctacacat aaggacctga aacctaaatg
     9001 gtcaaagccc gactatttag gtttcaggcc acttatgtgt aggtttctaa acgcgccagt
     9061 tcacgctctg acttaaacgc gttcgctggc gcagctcggc tatgcgaaga acagtgacac
     9121 agatggtcca aagcccagac catctgtgtc actgccactt cgctacgccg agctaaccgc
     9181 gccagttcac gctcttgtca tttttaacgg gtcgacccat ttatcaaact gcgctgctgt
     9241 gacgtcgccg cttttgatgg cggctgcttt tagatcgagg ttttcttgct cagccaattg
     9301 cgcgatggcg gcactttttt cgtagccgat gtggggtgcg agggcggtga ccagcatgag
     9361 cgaatgatca acgagtgctc tcatatgcgg tgcgtggatg gtcaagccgg caactaattt
     9421 ttcagtgaaa ctcgtgactg ttttggttag tagatcagct gactctaaaa aggtactgat
     9481 gataaccggc ttgtagacgt tcaattcaaa attgccttgt gacgcggcca ccgtgatcgt
     9541 cgtatcgttg cccatgactc gaacagcggc catggttagc gcttcggcct gtgtaggatt
     9601 cactttgccc ggcatgatgg aactaccagg ctcattggcc ggaatgcgca actcgccgta
     9661 tccagcacgt ggaccactgg caaggaagcg aatgtcattg gcgattttaa gcagatccgc
     9721 cgctagcgtt ttaatggcac catgaacaac gctaatttct gagtgagccg ctaaagcagc
     9781 aaacttattg gttttcgccg aaagtggtaa ttgataaaca tcgctcaatc ggcccgccac
     9841 aatcttgcca aaattagggt cagcgttaag ccccgttccg actgctgttc cgccaatggc
     9901 taagtaaaaa agattgggct gaagctgctt taaagcaatc tgatcatgct ccatcatggc
     9961 cacccatccg ctgatttctt ggccaaacgt tagcggcgtt gcatcctgta aatgagttcg
    10021 accgatttta acaacacgag cgtaagtgac ggcttttgaa tataaaacac tgcacagttg
    10081 gttgacagcg tgcagcaact gattcactgc aatagccgcc gtaatattca tcacagttgg
    10141 aaaagtatca ttggagcttt gactgtgatt cacatcatca ttcggtaaga tcggcaagtc
    10201 ggggttgagt tttgcagctt ggtggctaat gacttcgttc acattcatat ttgtttgtgt
    10261 gccagaccca gtttgataga catgcaatgg aaaatctttt tgcagttttt cgtctggcaa
    10321 ggccaacaag gcatcgactg ctcgcgtgat taattggcct tttggtgccg gtaaaacatc
    10381 agcggccaca tttgctcgcg ctgccgcttt tttgagttgc agcaaggccc taatcactgg
    10441 catcggcatc aatggaccag cctgaaaatt atgccggctg cgctctgttt gcggtcccca
    10501 caaagcgttt gccggaat
//
