LOCUS       gnlProkkaEIGOLAPF_88   10446 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EIGOLAPF_88.
ACCESSION   gnlProkkaEIGOLAPF_88
VERSION     gnlProkkaEIGOLAPF_88
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:00:27
            Original ID  :: gnl|Prokka|EIGOLAPF_88
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 90325
            Orig. end    :: 100771
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10446
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5446]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5446
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10446
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10446
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             10..1386
                     /locus_tag="ctg66_93"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAIKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLRMTRA
                     "
     CDS             complement(1648..2811)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     290.9; E-value: 2.1e-88)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_94"
                     /transl_table=11
                     /translation="MSGYHFLKPFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDKIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPRAGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTYLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
     CDS             complement(2837..3571)
                     /NRPS_PKS="Domain: PKS_KR (6-169). E-value: 6.9e-12. Score:
                     37.5. Matches aSDomain: nrpspksdomains_ctg66_95_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.7; E-value: 1.3e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_95"
                     /sec_met_domain="adh_short (E-value: 3.1e-34, bitscore:
                     111.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKDKVVVITGASSGIGAATVQVLAKAGAKLVIGARRTERLAEL
                     AASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEW
                     ERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIM
                     DGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVAKAVLY
                     AIDQPANVAINEVLLRPVTQER"
     aSDomain        complement(3065..3553)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg66_95_PKS_KR.1"
                     /evalue="6.90E-12"
                     /label="ctg66_95_PKS_KR.1"
                     /locus_tag="ctg66_95"
                     /protein_end="169"
                     /protein_start="6"
                     /score="37.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAKAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       complement(3470..3550)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg66_95_0001"
                     /evalue="5.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg66_95"
                     /protein_end="34"
                     /protein_start="7"
                     /score="12.7"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAKAGAKLVI"
     CDS             3776..4729
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     223.7; E-value: 5.1e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_96"
                     /transl_table=11
                     /translation="MKQVRLGGSNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQIALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             5001..5234
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_97"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-14,
                     bitscore: 47.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYNYRQLDDFQLSGVSGGKKKFDCAATFVTGITAGIGSGTITGL
                     AGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             5231..5446
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_98"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.5e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             5582..5890
                     /locus_tag="ctg66_99"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILLL
                     NRDLKLSSKGLSRLINPQNPYIVLTTLDGRLDFTFISMSNLKKLKSELMSLEIKSMD"
     CDS             6161..6757
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 109.3;
                     E-value: 3.2e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_100"
                     /sec_met_domain="Mac (E-value: 5.1e-10, bitscore: 32.4,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEEKFAFMATGKPYDDMDPLLLAVRDEATAKTDALNNEHDPAK
                     RNALFRKLVGQTGVKPFVNPNFHCEFGRNIRVGDHFYANYDCTILDGAPVTIGDHVLFG
                     PKVGLYTSNHLFDPLERQLGGCIAKPIVVGDGCWLAANVTVLPGVTIGAGTIIGAGSVV
                     THDIPARVIAAGNPCEVLREITAADKTGFAGHDMI"
     CDS             6876..7211
                     /locus_tag="ctg66_101"
                     /transl_table=11
                     /translation="MTDKRETLMSMLSKAYSSPTIKAEPELRALIETNAKKVDEGDDDK
                     AYVTAVTQLSHDISKYYLIHHAVPEELVAVFNYIKKDVPAADIDAARYRAQALAAGLVA
                     IPIVWGH"
     CDS             7530..7715
                     /locus_tag="ctg66_102"
                     /transl_table=11
                     /translation="MTLNKAIHFLLLIGISGVFLFTLAAAMGWVNQGDFALPLLLLAAG
                     LTLLRETDAGYEKARH"
     CDS             7967..8299
                     /locus_tag="ctg66_103"
                     /transl_table=11
                     /translation="MNMIQRNKVYFIMTGLNESFQKTATVSVMNTDAQEVIDDALHILK
                     KENVLQNRAIDYALARLYSRFVRLIGLQGMKLSPEADQWWQQLKDFMENDIHEELSQVG
                     GPHFIT"
     CDS             8811..9668
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg66_104"
                     /sec_met_domain="Abi (E-value: 5.6e-12, bitscore: 38.8,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKAGFVNLDEGDGMKKKRQRLFTPGLRVLYIFILDEFIEAFVF
                     TPFLSFLQLDFWADIVLYKVLSLVIILGLNLLLLRQKIIFRTSFGWPSWQKFVFWDIVG
                     CLVAWQIFTNRNFLDILQASVIGTIAAVPEEYLYRGVIFGGLLRAFYLANRGGTKRNFL
                     YCMLLSSLAFSLAHLSNLPSQGAVATVGQMIQVSGMGMLLAALYVRYGTLLMPIFVHFM
                     IDCLVTLIHGPYPSKLNGVSDEATLITVSLIWATIYLAISMWVLWHCHDEEGFMARLAG
                     QAIK"
     CDS             9779..10048
                     /locus_tag="ctg66_105"
                     /transl_table=11
                     /translation="MTKSKKSQRMIMILALSAIQVMILSILYRIINPKEFASMIYQVNA
                     NNTMRFVIIAVILFTFIASMISSSLLVSVFDFLRSGLFKKGNSK"
     CDS             10252..10437
                     /locus_tag="ctg66_106"
                     /transl_table=11
                     /translation="MSFRKVSSFIVGGGFLFAIVWLILSDLDLLPHISFIDRYYLIFLV
                     IFIVVCEKSQKNKPTN"
ORIGIN
        1 gaggtaaaca tgagcaaata tcgaacagaa acggacacat taggaccagt tgaaattccg
       61 gcaaacgctt tgtggggacc gcaaacagag cgcagccggc ataattttca ggctggtcca
      121 ttgatgccga tgccagtgat tagggccttg ctgcaactca aaaaagcggc agcgcgagca
      181 aatgtggccg ctgatgtttt accggcacca aaaggccaat taatcacgcg agcagtcgat
      241 gccttgttgg ccttgccaga cgaaaaactg caaaaagatt ttccactgca tgtctatcaa
      301 accgggtctg gcacacaaac aaatatgaat gtgaacgaag tcattagcca ccaagctgca
      361 aaactcaacc ccgacttgcc gatcttaccg aatgatgatg tgaatcacag tcaaagctcc
      421 aatgatactt ttccaactgt gatgaatatt acggcggcta ttgctgtgaa tcagttgctg
      481 cacgctgtca accaactgtg cagtgtttta tattcaaaag ccgtcactta cgctcgtgtt
      541 gttaaaatcg gtcgaactca tttacaggat gcaacgccgc taacgtttgg ccaagaaatc
      601 agcggatggg tggccatgat ggagcatgat cagattgctt taaagcagct tcagcccaat
      661 cttttttact tagccattgg cggaacagca gtcggaacgg ggcttaacgc tgaccctaat
      721 tttggcaaga ttgtggcggg ccgattgagc gatgtttatc aattaccact ttcggcgaaa
      781 accaataagt ttgctgcttt agcggctcac tcagaaatta gcgttgttca tggtgccatt
      841 aaaacgctag cggctgatct gcttaaaatc gccaatgaca ttcgcttcct tgccagtggt
      901 ccacgtgctg gatacggcga gttgcgcatt ccggcgaatg agcctggtag ttccatcatg
      961 ccgggcaaag tgaatcccac acaggccgaa gcgctaacca tggccgctgt tcgagtcatg
     1021 ggcaacgata cgacgatcac ggtggccgcg tcacaaggca attttgaatt gaacgtctac
     1081 aagccggtta tcatcagtac ctttttagag tcagctgatc tactaaccaa aacagtcacg
     1141 agtttcactg aaaaattagc tgccggcttg accatccacg caccgcatat gagagcactc
     1201 gttgatcatt cgctcatgct ggtcaccgcc ctcgcacccc acatcggcta cgaaaaaagt
     1261 gccgccatcg cgcaattggc tgagcaagaa aacctcgatc taaaagcagc cgccatcaaa
     1321 agcggcgacg tcacagcagc gcagtttgat aaatgggtcg acccgttaag aatgacaaga
     1381 gcgtgagctg gcgcggttag ctcggcgtag cgaagtggca gtgacacaga tggtctgggc
     1441 tttggaccat ctgtgtcact gttcttcgca tagccgagct gcgctggtga acgcgtttaa
     1501 atcagagcgt gagcaggtga tgatcacacc ttgatttaaa acttataaat cactggtagc
     1561 tccaggcacc atcgcgtaag ttgaagacgg caagaaaaaa gccgagcttt ttacagctcg
     1621 actcgcacga tgatttgaaa tgctagatta atcttgaggc acgttgcttg atgtcataga
     1681 ctgcgcagtt gttaacggga caccttttgc cccaccggaa atactttcga taaaatcgag
     1741 gaaggtcggc gcaatgccaa gttcttcaag atcagcaggg gcgatctggt aacggatcgc
     1801 cttttcgtca tggtctaaga ccttctgaac ccagtgcggc tcgcgaatca tttcgtgacc
     1861 aatggcgacc aagtcaaagg aatctgccgc tttctcagca tcggctggcg ttttcagacc
     1921 accaaccaca atcactggaa aagcaccggc gacgtggtca cgaatttgtt cattcatgat
     1981 ggctgtgtcc tcagggttgc gcaatgaggt tcgccaaacg tcactttggg agacatgcag
     2041 gtaatcaatc ttggtttgtt tcaaagcgtc gattaaggcc aaggtatcat ccaaggtaat
     2101 gccaggctgt tccaactctt ccggcgaaat gcggtagcct aacaaaaatg gccggtcagc
     2161 aattgtggca atcacttttt ctgcttcatg aacgactgcc aacggaaaac gcatccgctt
     2221 atcgcggtca ccgccccatt catcggttcg gcgattagag tttggcgaat agaattgctg
     2281 tatcagatag gtgttggcac catgcagttc gatgccatca aaaccagcaa ggatggcgcg
     2341 gcgcacagcc tgaccaaaat cgtgaatagt ggcctcgatt tctgccgatg tcaatgcgcg
     2401 cggtgtttcg taacccgccc gtggcgcagc aaccgcactg gcactgactg gctgctcacc
     2461 gcgcagaatc ttgctattgc tcatgcggcc agcgctgaag atttgcaaaa tagccttggt
     2521 gccgcctgtt ttcatcgcag cggcgagttt gctcaaaccg gggatgaatc gatcatcagc
     2581 gacacttagc tcaccttcga atcctttgcc aagcgcattg acattggcgg taccggtaat
     2641 aaacatgccg acgccaccgg cccgttgctg gtaatacctg attttgtccc gcgtcacagt
     2701 gccgtcttca aacgacaggc gcgttgtcat cggcggaatg acaatgcgat ttttcaacgt
     2761 gatggtttgg tgcttgaagg tgaacggttt taaaaaatga taacccgaca tgcaatcaca
     2821 ctcctttaga cgaaaattaa cgttcttgcg tgactggccg taagagcact tcattgatgg
     2881 caacattggc cggttgatca atggcataca aaactgcctt ggcaacatcc gaggcgctga
     2941 ggccattgtt tttttcatca gcttcaacag cttcacggcg cttaggatcg gtaattgtgc
     3001 tgaaaagctc agtattcacg gcaccgggcg agatcatggt cgttttaata tgattagccg
     3061 cttgttcttg tcgtaggccg tccatgatcg cctggatagc ccacttggta ccggagtaaa
     3121 cggcggttcc agggtgaaca atgtgaccgg caactgagtc tgttgtgata atttggccac
     3181 tgtgttgggc aatcataggt ggtaaaaccg cggcgatccc atacaagacg cctttaatgt
     3241 tgacgtcaat catacgttcc cattcgttga ctttgagttc ggccatttca gaaagtggca
     3301 tcaggccagc gttgttatac aaaacatcca catgaccaaa cttatccaac gccaaatcaa
     3361 tcagcgcttt cacttgctgc tggtcggtca catcggtttg ttgatacagc acctgaccgt
     3421 ccgtaaagct ggccgccaat tcagccaacc gttctgtgcg ccgcgcaccg atgactagtt
     3481 ttgcaccagc cttggccaac acttgtaccg ttgccgcgcc aatcccgctc gatgcacctg
     3541 tgattacaac cactttatct ttaactgtca aaatcacggc ctcctttatg ggcttatcct
     3601 gctaagaaaa aataagtaac agacacaggt taacctaccg cgcagctcag caccatgcaa
     3661 gctgttttat tgaaattcta atattggctt gacctcaagt ggactttagg ggctacactt
     3721 aacttgtcgt cagtaacata atttgaaatg acgtatcgaa gggagttttg tgtttatgaa
     3781 acaagttcga ttaggcggat ccaattggca ggcgtcaagt gtggccttgg gcatcatgcg
     3841 gatgaatgtg ctggcccccg acaaagcggc caatgtgctg gatagtgcgt acaatgacgg
     3901 catcaacttt atcgactcgg ccgacattta tggccaaggc aaatccgaag aagtttttgg
     3961 tgaagccttg aagcaagcca gcgtttcccg cgatcagtta ttcattcaat cgaaagtcgg
     4021 gatcgtcgtt gatccaaaac gctctcatgg cagtttggta ttcggcaaac ggtacgactt
     4081 ttcaaaagat cacttactgt cagcggttga tcacattttg aaacggttgc aggttgatta
     4141 ccttgattcg gtcttgctgc atcggccaga tccgttaatg gaagtcgatg acgttgcggc
     4201 ggcctttgat gcattggaac aaagtggcaa ggttcggcat tttggcgtct ccaactttaa
     4261 ccctgaacaa attgcgttgc ttgaaagcgg cattcggcag cctttgctga ttgaccaagt
     4321 tcaattctcc gttgcccata ctggcatggt caatgcgggg atgcacacca acatggccga
     4381 cgctgcctcg gtcgatcatg atggcagcct attaccatac ttgcaacgca aacacatgac
     4441 cttacaagca tggtcaccat tccaatacgg catgtttgaa ggcaccttta tcgatagccc
     4501 gaagtttaag gcgttgaatg atgaactgca gaaagtcgct gaccactacc acaccaataa
     4561 aaatgcaatc gcagtcgctt ggctattacg ccatccagtt ggtgtgcagg tgattctcgg
     4621 ctctatgaat cctgaacata tcaaggaaag tgcggaaggc gcggacatca cgttgacccg
     4681 acaagaatgg tatgacattt actttgcggc ggggaatgat ttgccgtaag ttgatgatat
     4741 gaaaaaattg tctcaaattg ctgagacgat tttttttgca aaaaattgaa gtttttacca
     4801 agcaaggaga tttaaacgtt aagaattttt gacttttaaa gcgcaactga acaataaaag
     4861 tgtaaagacg acgttaaact ggaaatttcc tacgtttaaa aaattttggc attttacaca
     4921 aataattaat gtatgttaaa gacagtaaag tcgaccttac acaaaataac ttgttgcttt
     4981 ttgaagaaaa aaggaaaatt atgtcttata attatcgcca gcttgacgat tttcagttgt
     5041 caggggtttc aggtgggaaa aagaaatttg attgtgctgc tacatttgtt actggcatca
     5101 cggctggtat tggatcagga acgattactg gcctagctgg tggtcctttt gggataatcg
     5161 gcggcgccgt agttggtgga aacttaggag cggttgggtc agctattaaa tgcttaggag
     5221 atgggatgca atgataagta aagaagtggg cattacttta aaacagcatg atttggtctt
     5281 aatccaagga ggagccaagc gacgcaataa acctagtggg tgtattgtgt ccacgatcgg
     5341 gggagcggta gcaggggcag ctggattaaa tccatttaca actgttgcag gcgctgcaat
     5401 aggattatcc ttgtgtctca gcactaatta cattcaccca gcctaatatt ggacaaagac
     5461 ggttagctcc tatcgcaact gttcaatata actaacacct tggtagtgct cactttttct
     5521 tgtcttagtc aaagatcgat ttcaaattag tctatttgtg caaaaggaag aggaaataca
     5581 aatggataag ataataagta tcatcatagt tatcttgatt ttactggcga cgatcgcttt
     5641 ttatctagca ccatttgttg gaggactttg gcaaggggca gcaagaagca aagtcattgc
     5701 caagatactt ttgttaaatc gggatttgaa actatctagt aaggggctga gtaggttaat
     5761 caatccccag aacccttata tagttctcac tactctagat ggaagacttg actttacatt
     5821 tatctctatg tcaaatttaa aaaagctaaa atctgagtta atgtcacttg agattaagtc
     5881 tatggattaa gctgataaag tccgaggaag tagctgaaat ttcctaacgc cagaattttg
     5941 tgacgatgaa gactgtaact gtatgtttct gtttgtaaca aaacaggcgt ggttctgtgt
     6001 gcagaagcga tgtcattgtt ttcaagccac catttcttca agaagtggtg gctttttgta
     6061 gacttcatgc gtaccgataa gcacacctta acatattggc aattatcaac gcagtgcgca
     6121 aatgtctggt aaacttgagc catgaaagaa aggtggcgca atgaatctag aagaaaagtt
     6181 tgctttcatg gcaaccggta agccatacga cgatatggat cctttgttac tggctgtgcg
     6241 ggatgaagca actgccaaaa ctgatgcact taacaatgaa cacgatccag ccaaacgcaa
     6301 tgccttgttt aggaaattgg taggccaaac tggcgtcaaa ccgtttgtga atccaaattt
     6361 tcactgtgag tttggtcgaa atatccgtgt aggcgatcat ttttatgcca attacgactg
     6421 taccattttg gacggggcgc cggtgaccat tggcgatcac gttttgtttg gcccgaaagt
     6481 cggtttgtac accagcaacc atctttttga tccgcttgaa cgacaacttg gtggctgtat
     6541 tgctaaaccg attgtagtcg gggatggctg ttggctcgct gccaatgtga cggtgctacc
     6601 aggcgtcacg attggtgcgg ggacgattat cggggcaggt agtgttgtca cccacgacat
     6661 cccagcgcgc gtgattgcgg cgggtaatcc ttgcgaagtg ctccgcgaga tcacggctgc
     6721 tgataaaaca gggtttgcag gacatgacat gatctaaacg ctgaattgat acttgaaaat
     6781 ggcaattgac aagcgcattc taacaatatt cacaatgact aaagtgctct gagtgagcat
     6841 gaattgccag gttaatcatc gaaaggaagt gcaggatgac agataaacgt gaaactttaa
     6901 tgtcgatgtt aagcaaggca tactcaagtc cgacgatcaa agcagagccg gaattgcggg
     6961 cgcttattga aaccaatgcc aaaaaggttg atgaaggtga tgacgataag gcttatgtga
     7021 cggctgtcac tcagttgtcc cacgacattt ccaaatacta tctgattcat cacgccgtac
     7081 cagaagagct ggtggccgtt ttcaattaca tcaaaaaaga tgtacctgct gccgatattg
     7141 atgcagcacg ttatcgcgcg caagccttgg ccgctggctt agttgccatt cccattgttt
     7201 gggggcatta gccgatgtag ggctgtgaat tttaaacggt gaggctaaag ttgatgatca
     7261 atcagttatg atttgccaaa aacgtcgcag actaagatct gcggctattt ttttgccatg
     7321 aaacttgttg acaccagtta agaaaaaccg agtagcagat cgataaagag aaaatttggt
     7381 cgatatttga caaaaaagcg acgttaatcg ggcaaaaccc tacgtttaaa aaagtttgcg
     7441 ctgttgtgtg aactatccag tatagtgtgc gtgaaagcat ccgcaagaaa aagtcgaagt
     7501 acatctggac gaggggatac aagttggcga tgacgttgaa taaagcaatt cattttcttt
     7561 tactgatagg catcagtggt gtctttcttt ttacgctggc tgccgccatg ggctgggtca
     7621 accaaggtga ctttgcgctg ccactactgc ttttggcggc aggactcacg ttgttgcggg
     7681 aaactgatgc cggatatgaa aaagcgaggc attgaattgg gtctgcttag aaggtagaaa
     7741 aacgtgaagc cgaatttctg tacacaagga caaactgatt ttaaaatgta atcggttacg
     7801 atgactcata tctaaaagag ttcaaataca agacggtatc aagatccatc agtcgggcta
     7861 taaagccatt gttttccggt gctttgccta aaagccatag catcgatact tttcaaacat
     7921 ttctatagaa aaattgtcac gacatcaaag gaaatggtga catatcatga acatgattca
     7981 gcgaaataaa gtctatttta ttatgacagg gctcaacgaa agctttcaaa aaactgcaac
     8041 cgtcagtgtc atgaataccg atgcacaaga ggtcattgat gatgcgctac acattttgaa
     8101 aaaagaaaat gtgcttcaaa atagagccat tgactacgca ttagcgcgcc tgtattctcg
     8161 ctttgtccgg ttaattgggt tgcaggggat gaaattatcc ccagaagctg accagtggtg
     8221 gcaacaactg aaagatttca tggagaatga tattcatgaa gagctgagtc aggttggcgg
     8281 accgcacttc attacttgat cggtttgttc ccaatattgg cacacgcaaa tgcgaagtcg
     8341 gaagtcgagt gttacgctgt ttatactgtg acttaccact ttatttagac tggttgggga
     8401 aggggcacga tgagatgcat cgaataaaga atgatgattt gcaacaaata attgaaggga
     8461 tgacctagcg taaattcctg acaatgctga ttttaggatt gattgcgata gatgcttggt
     8521 cacacactga ccaaattatt gcggggtttt taaagggatg gcagggcatg taggtgtttg
     8581 tgaccggtga agaattgcgc caattgcaag ctccgcgact ttttcaacac tgcagcgtca
     8641 cttcttcttg gcttagcgta gcgtcgttta ccgagtgaag tggctttttt gtcaataaat
     8701 gaccgctagc gaatttttga cggatgatcg tcaacgttaa atggcgaaaa cacgacgttt
     8761 aaaattagtt gactaaaagc cattcattaa tcggtatatt gttcatagca atgtcggaaa
     8821 aagccggctt tgtcaacttg gatgaaggtg acggaatgaa aaagaaacgg caacggttgt
     8881 tcacgcctgg attacgtgtt ttatacattt ttatcttgga tgaatttata gaagcatttg
     8941 tgttcacccc atttttaagt tttctacagc tggatttttg ggcagacatt gtgctctata
     9001 aagtacttag tttagttatc attctggggc tcaatctgtt gctgttaaga caaaagatta
     9061 tctttaggac gtcatttggc tggccaagct ggcagaaatt tgtgttctgg gatattgtgg
     9121 gctgccttgt ggcttggcaa atctttacca accgaaactt cttagatatt ttacaagcaa
     9181 gtgtcattgg taccatcgcc gctgttcctg aagagtacct gtatcgcggg gttattttcg
     9241 gtggcttgct ccgcgccttt taccttgcta accgtggtgg taccaaacgt aactttctct
     9301 attgcatgtt actaagcagt ctggcgtttt cgcttgcaca cttgagtaat ctgccaagcc
     9361 aaggtgctgt tgcaactgtg ggtcagatga ttcaagtcag cgggatgggc atgctgctgg
     9421 ctgctctcta cgttcgttat ggcacattac tgatgccgat ttttgttcat ttcatgatcg
     9481 actgcttggt aacgctgatt cacggccctt atcctagcaa attaaatggg gtaagtgacg
     9541 aagcgacgct cataactgtt tcgttgatct gggctacgat ttacttggcc atttccatgt
     9601 gggtcctatg gcactgtcat gacgaagaag ggttcatggc aaggttagca ggccaagcaa
     9661 tcaaataagt ttatagtatc ttggacacat tcactcgcaa ttgcggaaaa ctttattact
     9721 ggatatgata atcgcttatt taattatagg aagatccaaa aaagaggagc tgaatcaagt
     9781 gaccaaatct aaaaaaagtc aaagaatgat tatgatcctt gctttgtcag caatacaggt
     9841 aatgatactc agtattctgt acaggattat aaatccaaaa gaattcgctt ctatgattta
     9901 tcaagtcaac gctaacaata caatgagatt cgttatcata gccgtgatat tgtttacctt
     9961 tatagcgagc atgataagct cgtctctttt ggtgtctgta ttcgattttt tgaggagtgg
    10021 tttattcaaa aaaggaaact ctaaatgatt ttcatctgtg aatatgactt tcgttttctc
    10081 gtgcacactt aaacactttg ccagaccaag gtgttattgc aactgttgaa cagataattc
    10141 aagtcagcgg atcatgatgt ctatatgcat ttaatctcct caattggcaa atgaaacgtt
    10201 tgtattattg caaaaataaa cattgaagaa tgatagagag tgggtctgtt tatgagtttt
    10261 agaaaagtga gcagctttat tgttggtggc ggctttttat ttgctatagt ttggctgatt
    10321 ttaagtgatc tagatttgtt acctcacatt tcatttattg atcgctacta tttgatcttt
    10381 cttgttattt ttattgtggt gtgtgaaaaa agtcaaaaaa acaagcctac aaattaagcg
    10441 atgacg
//
