LOCUS       c00119_gnlPro..        15777 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNCKCBKI_119.
ACCESSION   c00119_gnlPro..
VERSION     c00119_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 22:19:10
            Original ID  :: gnl|Prokka|HNCKCBKI_119
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15777
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15777
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2532:5777]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2533..5777
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15777
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15777
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..121
                     /locus_tag="ctg119_1"
                     /transl_table=11
                     /translation="YILCEVVFEETASCHSRNIYVGDYLIRNFIQHPIVAAFF"
     CDS             complement(478..1410)
                     /locus_tag="ctg119_2"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVLDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELINAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
     CDS             complement(1440..2408)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg119_3"
                     /sec_met_domain="LysR_substrate (E-value: 4.4e-27,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.5e-19, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             complement(2533..3384)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_4"
                     /sec_met_domain="Radical_SAM (E-value: 7.6e-26, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             complement(3419..3550)
                     /locus_tag="ctg119_5"
                     /transl_table=11
                     /translation="MSLLGPSSKKCKQLNSRQEAIPVLPKDGNDAVAVFWQNEMKIN"
     CDS             complement(3516..5777)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_6"
                     /sec_met_domain="Gly_radical (E-value: 1.1e-41, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 4.9e-244, bitscore:
                     802.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDDVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             complement(6029..8473)
                     /locus_tag="ctg119_7"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVIAAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             complement(8480..10492)
                     /locus_tag="ctg119_8"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKHAFEEHFINGGHPDGSLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLRERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             complement(10804..10929)
                     /locus_tag="ctg119_9"
                     /transl_table=11
                     /translation="MVLMPKRTRSNLRVRTLGAMVKVQPSHPRPLMLRFLIGLLY"
     CDS             11209..11916
                     /locus_tag="ctg119_10"
                     /transl_table=11
                     /translation="MYVRFILLTYHSKVKNAKIVSSLRGGAHLILVLCFILAYFIGAIP
                     FGVVIGKLFYHTDIRKGGSHNIGTTNAYRMLGPVGGSIVLVLDILKGTLAASLPILFGI
                     EHHWLVLIVGLAAVFGHTFSIYIRFKGGKAVATSAGILLAYNPPFFVIAFAIWFSLILL
                     TSMVSVASTLGMVLITAWSLVYHDWLLTTVACGLLVVFLIKHRANFKRIKAGDENMVPF
                     GLGQYLRQHRGRS"
     CDS             complement(11998..12876)
                     /locus_tag="ctg119_11"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(12912..14321)
                     /locus_tag="ctg119_12"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRLVKILVPAIRKEKNTNPMAEMMSMLQGMQNGK
                     MPAGDDADAGGEVTDDIRNKRLSVAEQLEKGLLEDHEITVAVNDEKKGGGMGDMYGQMG
                     IDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGIIFI
                     DEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAEAK
                     PSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKEAV
                     DRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGSVTVTQQYVDDKIGHI
                     AADSNMTRYIL"
     CDS             complement(14365..14943)
                     /locus_tag="ctg119_13"
                     /transl_table=11
                     /translation="MLRFLSASARAHLKRSMTMTTIAAVRKDGVTALAGDGQVTLGEKV
                     IMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRK
                     DPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDM
                     TPADIAKEAVNIAGNIDIFTNHNVIVESF"
ORIGIN
        1 atatatatta tgcgaagtag tgtttgaaga gacggcatcg tgccattctc gcaatattta
       61 cgttggcgat tatttgattc gcaatttcat ccagcacccg atagtcgccg cattttttta
      121 accgctgctt gcagccaagt ctttaaaagc ttctacaatc attggaaatc attcgatatt
      181 tttttgcttg agttttttcg ttaagtcaac aactatcaag ttgaattccc gaactcgtct
      241 cagaatgcgt ctctcaccat gcctcaaaac catccaaaat gacccatgac aacttgctgt
      301 tgattcgacc cgcgaattac tacacgaatt tcaaattcac gcatcacgag ttgctagtca
      361 gctttatatt taacagattt cgcaaaaaga tggctagaga ctttttgcaa acaaaaaagc
      421 cgcaactggc tagctgcgac tttccttaga acaattgtgt gcaattaaag atgaaagtta
      481 accttcaaac gtgctctgca ttggcggaac gacctgcttt ttgcgggaaa caaccccagg
      541 caatgccaaa cgcgcgtcct tgtcgaactg ttcgttaaaa gcactggcga ttttatcgcg
      601 gtcagcaccg actgcgaaac cagttgaatt gctgtccaag atgtcagtag caatcagcag
      661 gaaatcgtcg tagcctttcg cctgcgcctc tttggtcatg gcattgatca attcgtcctg
      721 acgtgcgtaa atgtcgttca gatcgacggt attgacctgt ccgatgcgaa tagacttgcc
      781 gcccatggtg aaactcttag catcgccttc gataatgtcc atatctgact tggcggccaa
      841 attagtgcct gccttcagca tggcaagacc atatgactgc aaatcaattc cggcaatctt
      901 cgccatttct ggcaaaatct tcttatcctt atcggttgcg gtcggcgact tcaacaacag
      961 cgtgtctgaa atcaaaccag aagccatcaa accagccaat gttggcgaaa tcttgaagcc
     1021 atattcctgg aacatctcaa aaatgacggt attggtgctg ccaaccggtt ctgctcggta
     1081 aaacagcggc gctgccgtgt ggaagttagc gatgcgatga tggtcgacaa cagaatcaat
     1141 cgtcacgtct tcgatatcac tgacactttg ttgaaattcg ttgtgatcaa ccaacatgac
     1201 atgatccgtc tcgttggctg ccgtcttgat aacccgcggt gcctgaacct tgaagtgatc
     1261 aaggacgaac ttagtttcat cgttcggttc gcctaatgct accgcctcaa catccgtgtt
     1321 gcctgcctgt ttctgaaatt ctgcccagct catggcactc gtaatcgcgt cggtgtccgg
     1381 gttctgatgc ccaaaaatca aagtcgtcat cttatctgat cgctcctcaa ctgaataatt
     1441 tacttatcaa gtttaacacg gttttcactg acccgcgaca agtaatcttt ttccttcaga
     1501 taatcgtcaa aggtctggaa gaagttcgag atccgcggaa tgtcagcttt ctctttgcga
     1561 taaacaaaag aaatctcaaa gcgaatggcc ggatcaaacg caatagcata ggccttgatt
     1621 tgatcagcgc gtgcccgaac aaaactggtt ggtaaggccg tgttgacccc tgacaagtta
     1681 acgaattggg ttaactgata tggcgtggtg aaatgtgcga ccacgtgcgg gaaatcaacc
     1741 atttgattct tgtacgcctc acgcagaagc tgtccaagga aatagtcgtc aggataagtt
     1801 gcccaaggtt cagctaaagt atctttgaaa tggattcgct tacggttagc caaggcgtca
     1861 tcgtggtgca agaacagcaa ttgttcatca ataattttct tgctggcgta tggtttccag
     1921 ttcttaatgg tttcatctgg cagattcatg atagccaaat caatctggtt gttttccaat
     1981 gattcccaaa tttcgtgacg ggtcatcatc cgtagcgtta cttcaacttc aggattcagt
     2041 tgatagtaat gagcaatgaa cgcaataaag gcgctatcct cgattgagct taataaccca
     2101 atattgattt ttccgacggt tgcactggtt gtttgttgaa tttcgtcggt tgtctggttc
     2161 aagatctcgt agatctcatg ggttgacttt aacatggtct gaccagcgtc agataaatgc
     2221 agtttcttcc cgacagaata aaacagcggt gcccccactg tccgttccaa tttcttgatc
     2281 tgctgtgtta aggctggctg ggtaatgcca agcaattggg cggcttgggt gtagttcatg
     2341 gtttctgcca attgcagaaa ataagttagt gtctttgagg aaaaaatgcg ctcttgtttc
     2401 gttttcatag ggcggcttcc ctttcgttta ttatttaata atatcgttca accatcatca
     2461 taagtggcaa tgaaaaaaaa cgcaacgaat ttgccgcgtt tttaatcgtt acgttaagtt
     2521 ctagctaaaa attcagttgc tcgcaactgg tttcggacgc cagctttgcc atccggtata
     2581 atccttaacg tgcagcagat tctctgcatt cttaacgcga tcggcagacg gcggttcgat
     2641 gccttcaagc gggtacgtaa tgccaagctc gtgatacttt ttaacgccta acgtgtgata
     2701 cggcagaatc tcaacttttt ggaccacgtt tttgtccaat gtcgcaatat agtcccctaa
     2761 tcgtttgaga taagggtcaa agtcagtgcg ttccgggacc agaacgtggc gaatccacat
     2821 gtcatcacca tgcgccgaca tatactgcac catatctaaa atattttcat taggaaaacc
     2881 ggtgagcttt ttatgctcgg ccgaatcgat gtgtttaata tcaactaatg agatgtcagt
     2941 aacagccatc agcttttcaa actggccaaa ccacggttgg tcacgcgtga aggggccgcc
     3001 tgacgtatcg aggcaagtcg aaattcccag tgccttagcc ttggtgaaga gttcgagaat
     3061 gaaatcgatt tgtaccaaac tctcaccgcc actgcacgta ataccccctt ggtcacccca
     3121 gaatgcttta tagcgctggg catccgccaa aatttgatcg gccgtcattt cttcaccaac
     3181 cccaatgttc caggtgtcag ggttgtgaca atactggcaa cgcatgcgac acccttgcat
     3241 aaagacaacg aagcgaatac cagggccatc gaccgaacca aaactttcga ccgagtgaac
     3301 ataccctttg atcgggccat catgatcctg accaacttgt tctaagatat ttaatgggct
     3361 ttgtgactga tcgatgagtt tcatcttatt gcctccacta caacatcatg tgtcgttttc
     3421 aattgatttt catttcattc tgccaaaaaa cggcaacagc atcgttgccg tcttttggca
     3481 aaacaggaat ggcttcctgt cttgagttaa gctgcttaca tttcttcgaa gaaggtccga
     3541 gcaatgacat cgtcttgttg ttccttggtc aaatctgcga agtagacgca gtagccagaa
     3601 acccgaacgg tcaatgttgg gtattcttct gggtgcttct gagcatcaat cagggtctcc
     3661 ttgttgaaga cgttgatgtt caaatgcatg ccgctgtttt ccatatagcc gtcaaccatg
     3721 tgaaccaagg tatccttacg agtttcatca tcgtggccca gtgtgttcgg agtaacccca
     3781 aacgtattac taatgccgtc agttgcgtaa tgatacggaa tcttggcggt ggacatcaag
     3841 gatgccaatg cgccgttctt ttctgcgccg tatgccgggt tggcacctgg tgagaatggt
     3901 tcgccttttt gacgaccgtt tggtgttgtc cctgtattct taccataaac cacgttggaa
     3961 gtaatggtca ggacactggt actcaacttc gcgccgcgat acagatgatg cgtgttcatc
     4021 ttgttataga aggtcttaac caaccactta gcgatgtcat cagcgcgatc atcgttgtta
     4081 ccataacgtg gatagtcatc attgtcagca acgaagtcaa ctgcaacacc attttcatcg
     4141 cgaattgcct tgacatgacc atacttgatt gcactgatgg aatcaaccgc gtgtgacagg
     4201 ccggaaatcc cggttgcgaa ggtccggttc agttgggtat ccttcaatgc cagctgtgca
     4261 gcttcataat aatacttgtc atgcatatag tgaatcacat tcaaagcatt gacatacgtg
     4321 tcggccagcc agtccatcat cttgtcgaac ttattcatga attctttgta atcaatgtaa
     4381 tcgctggtga tcggtgcata ttcaggccct acttgcgctt cctgaatttc atctttacca
     4441 ccgttgatcg catacagaac cgtcttagct aagttagcac gggcaccaaa gtattgaacg
     4501 ccatcagcaa ttggttgtgc cgagacacag caagcaatac cgtagtaatc ggtaccccat
     4561 tcattgcgca tcaggtcatc attttcatat tgaatggttg aactttggat ggatacttcg
     4621 gttgcatagc gtttaaagcc ttctggcaag cgttcgctcc aaagcaaggt gatgtttggt
     4681 tctggtgctg cgcccatgtt gtccaaagtc ttcaggaaac ggaaagccgt cttggtaacg
     4741 tggtgacggc catcattgcc cattcctgcc aatgacaagg ttgcccagat tggatcgcct
     4801 gagaacagtg agttatattc ttcagtccgg atgaaacgaa ccatccgcaa tttcataacc
     4861 aaatgatcaa tcagttcctg tgcctgttct tcgttcaatt tgcctaagcg catatcgcgt
     4921 tggatataag catcaataac cgtatcgatc cggccaacgg acattgcggc accgttttga
     4981 gtcttaacag cagccagata gccaaagtag atccactgaa cagcttcttg cgcattagct
     5041 gccggacgcg agatgtcata gccatattcc ttggccatct tcttcatgtc gtttaaggca
     5101 cgatattgtt cattgatttc ttcacgcaat ttgattacat cgtcagtcat ttcgccgtcg
     5161 ccggtcaagt tataatcctt gaacttctca gccattaaac gatcgatccc gtaaacagcg
     5221 atccgtggga aatcagaaac aatccggccg cggccgtatg cgtctggcaa gccagtcacg
     5281 atcttgtaat ggcgagcctt tcgcatatca ggggtataag catcaaagac accttggtta
     5341 tgggtcttac gatattcatt gaaaatcttg tgttcttgag gatctgtctt gaagccataa
     5401 gattccaatg catcttcagc cattcgaata ccgccaaatg gcatgaatgc tcgtttgaat
     5461 ggcttgtcgg tctgaacacc aacaatcttt tcaagatctt tgttcaaata accagggccg
     5521 tgtgaggtga tcgtagatgg aatattgttg tcagcatcca aaacaccgcc atttgcacgt
     5581 tcttgcttct ttaaatttag aacctgattg ttcaggactg ttgtcgcttc agtggggcca
     5641 gcaaggaaac tttcgtcccc gtcatattgg ttcaggttat gctcgataaa atcgcgcaca
     5701 ttaatttctt cttgccagtc gccgccgtta aagccttccc aataattagg aactttggtt
     5761 tcgtcaagct gtttcatagt tgtttgcctc ctaaagtgga ttacagatgt gacagttctt
     5821 acaaacacag tataacacgc cgccaaatct atgcaagcgt tttattgccc atataatagg
     5881 cgttatattg ttttttaagt gtgcttcgtc gcttcttttc gcccatgatt tcggcatttt
     5941 gttaaattgt gcacaactgg tctgtcctat aataatcaaa aacgccacca tctgtattag
     6001 tacagacggc ggtgtcaatg atcaccattt attcgacttg atctgctggt tcttctttgg
     6061 tttgaacaaa aactggcttg ccaaggacat cagtgtcaat gacaaacgaa ccattcgaat
     6121 agcggtcacc tgctggatgt tgtgccggat taagggtcgt taccttaccc gtatcggtca
     6181 aaacattcag gcgggtagcg tcatcgactg acatcatcgc gacaatccga tgcggatcac
     6241 gcttaagctc acgcaagacc agtaaaccac gacgggcacg actcatttcc ccgacttcgc
     6301 ttaaggccat ctttttgaag gcgccacgtt gggtcaaaat accgacctta gccgtagttg
     6361 gatccttcac tagaatgaaa ttgacaacct catcgtctgg ctttagatcc atacttttaa
     6421 cgccggttgc ccgggcaccg acagttgaca catcgcttaa cgggaatgtc agtccgtaag
     6481 cgtggcggct gaccacaaag acatcctgtt gctgatcagt cgtgaagtat gcattggtga
     6541 caatcgcggc tgggtctttc agcttcatcg ccatcatcgg cttactcttg tacgtccgtt
     6601 gcggctgcaa atcacttaag gcagtttgtt tgatgtaccc gtcacttgac cctaacacaa
     6661 aactgccagc gccatcgagt tgatcaaaag caaacactgc caagactttt tcgtcagtgc
     6721 caaggccaac tgtttggctt aagtgttcgc cggtgtcttt ccaacgcgca tcactaattt
     6781 catgcactgg tcgataaatg acatttccgg catttgtcac gatgtaaagg tgctgcaacg
     6841 tactcagttc gccagtgaaa atggcaagat cattggcctt caaaccattg tcggccggat
     6901 caaccgcctg ataactgcgc agtgaactgc gtttaacgta cccatcacga gaaacctgca
     6961 ccatgacggt ttcatcagcc accgtcaccg ttgtcgccac ttcaagtgtt tcaattttgg
     7021 cttgaatgct gctgcgacga tcatccccgt actccttggc aatccgcttc aactcgcctt
     7081 caatcacccg atcgcgggca gcggggcggg ccaaaatatc ttgatactcg gcgattgctt
     7141 tcgccaattg tgctgcttct ttctgtaaag ccgtgatatc ggtattggtc aatcgataca
     7201 gctgcaagga aacaatcgct tccgcctgag cttccgaaaa atcaaacttc ttgactaagt
     7261 tacgcttagc atccccttta tccttggaag cacgaatcgc ggcgatgacc tgatccaaaa
     7321 tcgatagcat tttgatcaag ccttcgacaa tgtgctgtcg agcagcggcc ttgttgaggt
     7381 caaaacgcgt tcgccgagtg accacatcgc gtcgatgttc gacgtatgct tccaacatgg
     7441 ccttaagtcc tagcaacttc ggctgcatgt cggcaatagc gaccatgtta aagttgtatg
     7501 caatttgtag atcggtattt ttaaataaat agtttaagat gccatgtgca tcggcttctt
     7561 tttttaattc gatgacaacg ctaagcccaa aacggtcgct ttcgtcacgg acttcggcga
     7621 taccgtccac ttttttgttg atgcgtaatt catcgatttt tttaatcatc tgcgctttat
     7681 tgacatcata cgggatctca gtgaccacga tcttctcacg accgccacga atggtttcga
     7741 tgtgtgtccg agaacgaacc acgattttac cgcggccggt ttcgtaagct tgcttgatgc
     7801 catcaagccc ttgaataatc ccacctgttg gaaaatcggg acccttgacg tattgcatta
     7861 aagtatctaa atcagcagtg ggatgcttca gcaagtataa gacggcagca ataacttccc
     7921 gcagattgtg cggcggaatt tcggttgcat aaccggcaga aataccggtg gcaccgttca
     7981 ccagcaaatt tggaaaccca gctggcagca cagtcggttc ctgtgccgtg tcatcaaagt
     8041 tcaacaccat atcgacggtt tccttatcga tgtcggccag catttccttg ctgattttgc
     8101 ttaaacgcgc ttccgtgtat cgcattgcag ctggcggatc accatccatg gaaccgttat
     8161 tcccgtgcat ctgaatcagt ggggcccgta acttccaatc ctggcttagc cgaaccatcg
     8221 cttcataaat ggagctgtcg ccgtggggat gataattacc catgacattc ccgacacttt
     8281 tagccgactt gcggaagccc ttatcatacg tattgccatc ttggttcatc gcaaataaaa
     8341 tgcgacgctg aaccggtttg aggccgtcac gcacatcagg cagcgcccgt tcttgaataa
     8401 tgtatttcga gtaccggcca aaccggtcgc ccatgacctc ttctaaggtc agttcttgaa
     8461 tctgattggc caatggcttt tactttcctt tcttgtccag ttgtttgacg atttgcttgg
     8521 caccaaactg taatttttcg tgattagcag tcggggtttc caaaatactg ccgtcgtcat
     8581 ccatatcaaa cttgacgtta tgctcaatcc attcacgacg cggctcaacg cgatcaccca
     8641 tcaaagtggt cacgcgtcgt tccgccagct gagcatcgtc aatccgaacc cggatcaaag
     8701 tccgcgtctc aggattcata gtcgtttccc aaagctggtc ggcattcatt tccccaagtc
     8761 ctttaaatcg ggtcaatgtg taacccttgc ccatggcctt ggtctctttg gccaactctt
     8821 catcggtcca agcataactg atcttggttt tagcaccagc gcctttttgc agccgataca
     8881 atggtggcaa agcaatgtaa attcggcctg cgtcaatcag cggccgcatg tagcgataaa
     8941 agaaggttag tagcaaaatc tgaatatgcg cgccatcagt atccgcatca gtcataataa
     9001 tgattttgtc gtagttggcc tgctgcagat caaaatccgc accgacacca gcgccgatgg
     9061 tgtaaatcat cgtattgatt tcttcgtttt taacgatgtc ctgtaacttg gccttctggg
     9121 tattcagtac tttccctcgc aatggcaaga tcgcctgaaa ctttcggtct cggccttgtt
     9181 tagctgaacc accggcagaa tccccttcga cgagatacaa ttcgttacgc ttagggttct
     9241 tggtttgcgc cggggtcaat ttaccggaaa gcaaaccttg gtccttcttg cgcttgcgtc
     9301 ccgtccggct atcgtcgcgc gcttttcgag ccgcttcccg cgcatcacgg gctttgacgg
     9361 ctttacgaac caactcttgc gactcttcac cgttttccat caaaaaagtt gacagcttgt
     9421 catagacaat cccatcgacc acagtgcggg cttgcggcgt acctagcttg ccctttgtct
     9481 ggccctcaaa ttgcaaaatt tcttctggaa tgcggacact taaaatacct gcaaaacctt
     9541 cacgcacatc actgccttca aggttcttgt cgcgttccct cagcaagccg acttttcggg
     9601 caaattcatt gaatgctcgc gtcatgccgc tgcgcaagcc aatttcatgc gtcccgccat
     9661 caccagtgcg aacgttatta acaaacgaaa tcaggttttc agaatagcca tcgttatatt
     9721 ggccggcaaa atcaaccacg ataccgtcct ttttgccttc aaaattgatc acctgtgaca
     9781 atgcgtcttt gccttcatta aggtatttaa caaaactgac caagccatca ggatagtgat
     9841 aactgtcgtg cttaccggtg cgttcatccg tcagattaat cgtaatattt ttcagtagaa
     9901 aggctgattc gcgcaagcgt tcggccaagg tatcataact gaagacggtg gtttgaaaaa
     9961 tagtcgggtc cggcttgaat gtgatggtcg tgccattagg ttcattaact ttgcccaact
    10021 tctgcaaact gccatcagga tgaccgccat tgataaaatg ctcctcaaat gcgtgtttat
    10081 cccgcacaac tcgcacagtc aatgactccg atagggcatt gacgacgctt gagccaaccc
    10141 catgcaaacc accagaagtt ttgtaactat tttggttaaa ttttccgccg gcatgtagca
    10201 cggttaaaat gacttcaatc gtcggtttac cactcgggtg catccccgtt ggcatccctc
    10261 gaccatgatc ctgtacggtc acagagttat cggcgtgaat cgtcacattg atctcatccc
    10321 caaaccccgc gagcgcttca tcgacagagt tgtccacgat ttcatagacc aagtgatgca
    10381 aaccgcggcc atcggtggaa ccaatataca tccccggacg cttccgcaca gcttccaagc
    10441 catgcagcac ctgaatggat gaatcattat atgcttgcgt tgctttatcc atagtaaact
    10501 cccttttttg aacaactaag ttatagaata caccacgcgt tgagatttca gaaataaaaa
    10561 ataagagcgc gagccagccc gattagaaac cggagcataa gcggccttgg gtgcgatggt
    10621 tgggctttga ccattgtgcc caaggtcctt atgtgcaggt ttctgggctg gcgagcgcgt
    10681 ttcagtagag cgcgagcagg agcggttagc aaccggagtg taagcggcct tggacgtgat
    10741 ggtcggcttt gaccattgcg gccaagtccc ttacacgcag gttgctgcga ctgcgagcgc
    10801 gtttcaatag agcagcccga ttagaaaccg gagcataagc ggccttgggt gcgatggttg
    10861 gactttgacc attgcaccca aggtccttac acgcaggttg ctgcgagtgc gtttaggcat
    10921 caacaccatc aacagcagac ctcaacgtat tgctctcagg actcctgttt tctcctcaaa
    10981 atcgacccag ctggctaata ccatcattgt tcatttaaat tttattagcc gtgtcaatgt
    11041 cccaaagctc agcagaaaac cgcacttccc taagcatggc acataactat gacttcttga
    11101 cgtgaaattc atcgcccgct ggcaccatat ctacgctgtg ccccgccatg atccttgcgc
    11161 aagacaacac caaatcgcgc cacaacccgc ttcacaggtt ttattcgaat gtacgttcgt
    11221 tttattctac tgacgtatca ctcaaaagtc aaaaatgcta aaatagtttc tagtttgaga
    11281 ggaggggcac atttgatact tgtgctttgt tttatactcg cgtatttcat aggcgccatc
    11341 ccgtttggtg tggtcattgg taaactcttt tatcacacgg atatccgcaa aggcgggagt
    11401 cacaatattg gcaccacaaa tgcctatcgc atgttagggc cagtcggcgg ctcaattgtc
    11461 ttggtgctgg atatcttaaa aggcacgttg gctgccagct tacccattct ctttggcatc
    11521 gagcatcatt ggctggtgct gatcgtgggt ttagcggccg tattcggtca tacattttcg
    11581 atctacattc gctttaaagg cggtaaggcg gtggcaacta gcgctggcat tttacttgca
    11641 tataatccgc cattttttgt cattgcattt gccatctggt tcagtttgat cttgctaacg
    11701 tccatggtca gcgttgccag cacactgggt atggtgttga tcacagcttg gtcgcttgtt
    11761 taccatgatt ggttgctgac aactgttgcc tgcgggttgc tggttgtctt tttgatcaaa
    11821 catcgggcaa acttcaaacg catcaaggcc ggagatgaaa atatggtgcc ctttggctta
    11881 ggccaatatc ttcgtcaaca ccggggccgc tcttagtcac cttttgatgg caaccaaaaa
    11941 gacatccgaa actggatgtc tttttttcat gtacctaatc gacaaactga tgacacctta
    12001 gaaaatgctg atcatgtaac ccttctcaaa tgccgtgcca ggttcaagtc gattgatccc
    12061 gagtttgcgc gtcaggtcgc cagtgctgcc aatcgtgtcg gcgatgcccc accaaggttc
    12121 gatgcagaca aagtcgccag tggttggata cggactccaa acgcccagat atggggtatc
    12181 ggtcatggta acgctgacac catgtttcgt cttgtcagaa accaagttga aggttgtctt
    12241 accaagcaac gcgaaaatta aagcatcatg atcaaatgtt tcgtgcgtta aggccaaatt
    12301 ggcatcagtt gcagccaagg tccggtgcgt gtaatcaatg ccttcaccag caaccaatgg
    12361 aatctgaaca agcgacttac gcggtttgaa gttcaaataa taatcggaga attgagtatc
    12421 cggcgtcatt gggaccttga agcccggatg gccgccgatg ctaaagaaca gtggctcact
    12481 tttgtccgga ttgtcaacgt gatacgtgac atgtagattg ttattttcta gtgcaaacgt
    12541 gatgattaaa cgaaaagcga acgggtacat cgcccgcgtt ttgtcatcat ccttcagaac
    12601 gaagctcgct ttaaacggtg tcgcagagag caccgtgaaa tcacgatcac gggcaaaacc
    12661 gtgctggccc atgtggtaag tcttgcctgc gtaatgatat tgattgtcag ccagcgcccc
    12721 aacaatcggg aacaagaccg gggcgtggcg accccacacc gcaggatctg cttgccacag
    12781 acgctccctg cctgtcaggt tatctttgat actggtcagt tcagcaccat gccgactgat
    12841 tttaactgtc aaaaagtcat ttgcaatcgt taccatacat cctcatcctt tacctacaac
    12901 attattgtta actacaaaat ataccgcgtc atgtttgaat cagccgcaat atggccaatc
    12961 ttgtcatcca catattgctg ggtgacggtc acactgccca tcgccatatc tggaccttca
    13021 taaagtacgt cttcaagcag tttttcaaga atggttgcca gtcgccgcgc tccaatatta
    13081 tcagtgtcgt ggttgacctg agtcgcaatc tctgcaattc gatcaaccgc ttccttcgtg
    13141 aaggtaatct tcacgccatc tgcaccaatc aaggcgatat actgcttgat caaagcattg
    13201 tctggctcgg tcaagatccg cacaaagtct ttttcggtta agtccttcaa ttcaacccga
    13261 attggaaaac gcccttgaag ttcagcaatc aaatcactag gcttagcctc ggcaaacgca
    13321 cctgagccaa tgaacaagat gtgatccgta ttgataggac catacttagt gttaatctgc
    13381 gatccttcta caatcggtaa aatatctcgc tgcacacctt cacgcgaaac ttcgccgcta
    13441 ttatgcttgt ttcctgcagc aattttatcg atttcatcga tgaaaatgat cccgttattc
    13501 tcggcacttt gaatggcgtc gtgataaatg tcggcatgat tgaccagttt gtcagattcc
    13561 tctttgatga agatttcgcg agcttctttg acggtcatgg tccgctcaac ctttttctta
    13621 ggcattaaag cgccaatagt gtcgcttaga tcaatgccca tctgaccgta catgtcaccc
    13681 atgccaccgc cttttttctc atcattgaca gcaacggtga tttcatgatc ttcaagtaat
    13741 cctttttcca gttgctctgc cacgctcaaa cgcttattgc gaatatcatc ggtcacttcg
    13801 ccgcctgcat ctgcatcatc gccagctggc attttgccat tttgcatccc ttgcaacatg
    13861 ctcatcatct cggccatcgg attggtattc ttttccttac gaatggccgg cactaaaatt
    13921 ttaaccaaac gcttgttggc ttctttttcg gcacgtatgc gaacctttga aaattgcttc
    13981 tcttcttcca tggcaacggc agtttcggca agatctcgga ccatggattc gacatcacgg
    14041 ccaacgtagc caacttccgt aaacttagtc gcttccacct tcacaaatgg cgcctcaact
    14101 attttcgcca gtcgtcgtgc aatttcggtt ttcccgacac cggttggtcc gatcatcagt
    14161 aagtttttcg gggtaatctc ttcttgcatt tttggcgata attgcattcg ccgataacgg
    14221 ttatacaagg caaccgcgac ggcccgtttt gcatcatctt gtccaatgac atattgatcg
    14281 agtttttcaa cgatctgttt tggggtttgt acttctgcca tcataagcct cctgtaggtc
    14341 aatgtaattg ccgacggtta caaactaaaa gctttcgaca ataacattgt ggtttgtgaa
    14401 aatatcgata ttccctgcga tattcactgc ttctttggca atgtcagctg gtgtcatatc
    14461 tggggcatgc cgcagcatcg cgattgccgc ggcttgcgca aagttgccgc cggagccgat
    14521 cgctaccacg tcttcatctg gatctatcac ttcgccagac ccggatacaa gtaacaggtc
    14581 atgctcatcc atcacgatca tcatggcttc aagtttctgc aaggtcggat ccttgcgcca
    14641 atcttgagcc agcgcaactg cggaacgtcg caagttgcca gcataatgct ccagcttctt
    14701 ttcaaaccag tcttgcaggg tgaaagcatc tgccaccccg ccggcaaatc cgatgacgac
    14761 ttgatcatga tagatccggc gaactttctg cgcgttgcct ttcatgatga ccttttcgcc
    14821 aagggttacc tgaccgtcac cggccaaagc ggtcacacca tcttttctta ctgctgcaat
    14881 tgttgtcata gtcatgctcc tttttaagtg agcgcgagca gaagcgctta gaaaccggag
    14941 cataagtggg ctgcaagcct aaatggctga attttggcta tttaggcttg caggtcatta
    15001 tgtgtaggtt tctgcgactg cgagcgcgtt atctgcgtat ctcgtcggat aaaaacagct
    15061 aaagtagcga ttaatctgtt atcgccaatg ttcttagctt aaaaaactca gactgctttt
    15121 gcatcatgct ttagtcttaa ttatgcttcg gataatattt catatactca ttttttaaat
    15181 gtgccatggt gacatgcgtg tagatttgtg tggttgataa acttgcatga cccagtagct
    15241 cttgaacagt tcgcaggtca gcaccatgat ccagcatatg ggttgcaaaa ctatgccgca
    15301 gcatgtgggg atgaatgtta gctgtcagcg tcgtctgctt gatgagctga tccaaaatat
    15361 attcaatgcc acgcgaggta atcggacgcc catactggtt cacgaataca tatcgatgct
    15421 gtgcctgact tttagccatc aagacttgtc ggccatcttt taaataagtt cgtagtgctt
    15481 gctgagcgta ctgtccaaag ggcacatacc tatctttgtt gcctttacca tgaatcaaca
    15541 gtaatgccgt attgaaatcg acctgattca atgtcagttt ggcacactcg gaaactcgaa
    15601 taccggtgcc atacaaaact tccaacaaag cgcgattacg ttgatccagc ggggttttgc
    15661 cagcaactgt cttgaacagt tcctgaatct cggcttcata gaaaaattgt ggtaaatgat
    15721 gatgctgctt ttttaattca accagctcaa atgggttgcg tttgacgaca tcaattc
//
