LOCUS       gnlProkkaMHONCCNG_12   10554 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHONCCNG_12.
ACCESSION   gnlProkkaMHONCCNG_12
VERSION     gnlProkkaMHONCCNG_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:06:48
            Original ID  :: gnl|Prokka|MHONCCNG_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10554
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..3663
                     /NRPS_PKS="Domain: AMP-binding (175-568). E-value:
                     8.2e-116. Score: 378.8. Matches aSDomain:
                     nrpspksdomains_ctg12_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (673-741). E-value: 3.1e-24. Score:
                     76.9. Matches aSDomain: nrpspksdomains_ctg12_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (751-1053). E-value:
                     3.3e-168. Score: 552.7. Matches aSDomain:
                     nrpspksdomains_ctg12_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1059-1213). E-value: 9.5e-53.
                     Score: 170.0. Matches aSDomain:
                     nrpspksdomains_ctg12_1_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     338.5; E-value: 9.4e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_1"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-122, bitscore:
                     395.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.4e-15, bitscore:
                     44.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.3e-80, bitscore:
                     255.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLEL
                     TRDMSRNPLFDVMFVLQNMDQESLELNELCLKPAAHNGHQTSKFDLTLYTQEQPRGLLT
                     FQMEFSTDLYKKKTIEKWLQYFINMLLSIIKDNKAALGTINILNEDETHYLIHELNRTK
                     IDYPRNETISRLFEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPDSV
                     VALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEKQL
                     LDIECEQIIIEDIQKQGKTKNVDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRLVK
                     NSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIEHQ
                     GITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGYGP
                     TENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVARG
                     YLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVRGYRVELGE
                     IETAFRQIDGVKEAAVLARTAQTGSKELFGYISVKAGTNAEQVRSLLACSLPNYMIPAY
                     IIEMENLPLTSNGKLNRKALPEPDFASKQTYIPPRNELEEQLALIWQEVLGIQRIGIED
                     SFFELGGDSIKALQVSARLGRHGLSLQVSDLFRRPKIKDLSPFIRKTERVIEQGPVQGD
                     VPWTPIQKWFLSQDIEERHHFNQSVMLFHTDRLSEDALRASLKKLAEHHDALRMVYRND
                     DRRWIQINQGIHESQLYSLRTFDLSQSESGWETQIKQEVADLQQSINLQEGPLLHAALF
                     KTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQLPPKTDSYQEYARRIQ
                     EYAQSSKLIREEAYWRTVEEQQDAELPYEIPHQVNIDFSKRDSLNFSLTEADTAVLLQN
                     VNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTVGWFTSMY
                     PALISFENHRDELGTALKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEISFN
                     YLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPARFHR
                     NTMEQLINRIEHFLLDIMKHCAGQQKTEKTLSDFSSQSLTAEDLDSISSLVEEL"
     protocluster    1..10554
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[0:10552]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..10552
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10554
                     /SMILES="NC(C(C)C)C(=O)N1C(CCC1)C(=O)NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10554
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS_motif       64..183
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0001"
                     /evalue="8.70E-23"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg12_1"
                     /protein_end="61"
                     /protein_start="21"
                     /score="72.8"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVL"
     aSDomain        526..1704
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_AMP-binding.1"
                     /evalue="8.20E-116"
                     /label="ctg12_1_AMP-binding.1"
                     /locus_tag="ctg12_1"
                     /protein_end="568"
                     /protein_start="175"
                     /score="378.8"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPD
                     SVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEK
                     QLLDIECEQIIIEDIQKQGKTKNVDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIE
                     HQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGY
                     GPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVA
                     RGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     aSModule        526..3639
                     /complete
                     /domains="nrpspksdomains_ctg12_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg12_1_PCP.1"
                     /domains="nrpspksdomains_ctg12_1_Epimerization.1"
                     /domains="nrpspksdomains_ctg12_1_TIGR01720.1"
                     /locus_tags="ctg12_1"
                     /monomer_pairings="Val -> D-Val"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       712..750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0002"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_1"
                     /protein_end="250"
                     /protein_start="237"
                     /score="15.0"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       937..993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0003"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_1"
                     /protein_end="331"
                     /protein_start="312"
                     /score="33.3"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       1498..1587
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0004"
                     /evalue="4.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_1"
                     /protein_end="529"
                     /protein_start="499"
                     /score="57.4"
                     /tool="antismash"
                     /translation="PVGAVGELCVGGDGVARGYLGRPDLTKEKF"
     CDS_motif       1669..1734
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0005"
                     /evalue="1.80E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_1"
                     /protein_end="578"
                     /protein_start="556"
                     /score="39.1"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        2020..2223
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_PCP.1"
                     /evalue="3.10E-24"
                     /label="ctg12_1_PCP.1"
                     /locus_tag="ctg12_1"
                     /protein_end="741"
                     /protein_start="673"
                     /score="76.9"
                     /tool="antismash"
                     /translation="EEQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRHGL
                     SLQVSDLFRRPKIKDLSPFIRKT"
     aSDomain        2254..3159
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_Epimerization.1"
                     /evalue="3.30E-168"
                     /label="ctg12_1_Epimerization.1"
                     /locus_tag="ctg12_1"
                     /protein_end="1053"
                     /protein_start="751"
                     /score="552.7"
                     /tool="antismash"
                     /translation="GDVPWTPIQKWFLSQDIEERHHFNQSVMLFHTDRLSEDALRASLK
                     KLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRTFDLSQSESGWETQIKQEVADLQ
                     QSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQ
                     LPPKTDSYQEYARRIQEYAQSSKLIREEAYWRTVEEQQDAELPYEIPHQVNIDFSKRDS
                     LNFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       2347..2430
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0006"
                     /evalue="2.50E-05"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg12_1"
                     /protein_end="810"
                     /protein_start="782"
                     /score="16.7"
                     /tool="antismash"
                     /translation="TDRLSEDALRASLKKLAEHHDALRMVYR"
     CDS_motif       2635..2700
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0007"
                     /evalue="1.30E-12"
                     /label="NRPS-E2"
                     /locus_tag="ctg12_1"
                     /protein_end="900"
                     /protein_start="878"
                     /score="39.8"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVSWRILLEDL"
     CDS_motif       3106..3153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0008"
                     /evalue="5.80E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg12_1"
                     /protein_end="1051"
                     /protein_start="1035"
                     /score="27.9"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     aSDomain        3178..3639
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_TIGR01720.1"
                     /evalue="9.50E-53"
                     /label="ctg12_1_TIGR01720.1"
                     /locus_tag="ctg12_1"
                     /protein_end="1213"
                     /protein_start="1059"
                     /score="170.0"
                     /tool="antismash"
                     /translation="ELGTALKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEI
                     SFNYLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAR
                     FHRNTMEQLINRIEHFLLDIMKHCAGQQKTEKTLSDFSSQSLTAEDLDSI"
     CDS_motif       3202..3264
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0009"
                     /evalue="1.20E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg12_1"
                     /protein_end="1088"
                     /protein_start="1067"
                     /score="30.4"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGMLKYL"
     CDS_motif       3304..3333
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0010"
                     /evalue="3.90E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg12_1"
                     /protein_end="1111"
                     /protein_start="1101"
                     /score="9.8"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        3689..3778
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_NRPS-COM_Nterm.1"
                     /evalue="2.10E-18"
                     /label="ctg12_2_NRPS-COM_Nterm.1"
                     /locus_tag="ctg12_2"
                     /protein_end="30"
                     /protein_start="0"
                     /score="57.2"
                     /tool="antismash"
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS"
     CDS             3689..10552
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 2.1e-18.
                     Score: 57.2. Matches aSDomain:
                     nrpspksdomains_ctg12_2_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     1.7e-117. Score: 383.7. Matches aSDomain:
                     nrpspksdomains_ctg12_2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (468-865). E-value:
                     5.8e-105. Score: 343.0. Matches aSDomain:
                     nrpspksdomains_ctg12_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1040). E-value: 1.2e-23. Score:
                     75.0. Matches aSDomain: nrpspksdomains_ctg12_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1054-1333). E-value:
                     1.3e-101. Score: 331.4. Matches aSDomain:
                     nrpspksdomains_ctg12_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1900). E-value:
                     5.1e-113. Score: 369.6. Matches aSDomain:
                     nrpspksdomains_ctg12_2_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2002-2071). E-value: 1.3e-25.
                     Score: 81.3. Matches aSDomain:
                     nrpspksdomains_ctg12_2_PCP.2"
                     /NRPS_PKS="Domain: Condensation_LCL (2085-2288). E-value:
                     1.8e-70. Score: 229.2. Matches aSDomain:
                     nrpspksdomains_ctg12_2_Condensation_LCL.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     361.4; E-value: 1.1e-109)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_2"
                     /sec_met_domain="Condensation (E-value: 5.8e-89, bitscore:
                     285.1, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 9.7e-123, bitscore:
                     396.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-17, bitscore:
                     50.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEENITHLNEAEQSQF
                     IEQWKEKDRDQGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNASPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGK
                     SRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR
                     PAEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAYSYHPLYEIQSRSA
                     VKQGLIDHILVFENYPVQQEIQMLNKQEHASDLFQIHNFTVADETNYSFYLMVAPGEEI
                     HIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQLIGEITDQ
                     TPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQEPVA
                     IMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLPSSLED
                     NYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLLKFEY
                     THSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHQT
                     NIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRKRGIHLHNHYG
                     PSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA
                     RGYVNHDKLTSDKFSSDPFKPDVIMYRTGDLARRLEDGNIEYIGRADNQVKIRGYRIEP
                     QEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMIP
                     SKWIWVDSIPLTPNGKVDRAALPEPDASISGNPYTAPRNLLEAKLSQLFEDVLKNGHIG
                     IQDNFFDNGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLALIIREAEQNLYAAI
                     EPAEERDTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELISRHE
                     PLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFCLSQAPLFRAGLIEVSNEKH
                     VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKGDSYQKQE
                     TYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKNRSTLYMT
                     LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNKTFEEFL
                     KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMNDVQLQ
                     WNDLEHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWASLFTTLVEHTAASPE
                     TELDNIPILTKEEERDFIESCHLFEETGYSMNQTLHYALEQQAEKTPDQAAVIFEDGVM
                     TYKELNEQANRIAWELIGRGVKPETTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYP
                     EERISFLLEDSGTNILLLQSAGLHVPAFTGEIVYLNQTNSGLAHRLSNPNVDVLPQSLA
                     YVIYTSGSTGMPKGVEIEHRSAVNFLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWW
                     PYAGASVYLLPQGGEKEPEVIAKAIEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRL
                     KRVFSGGEQLGTHLVSRFYELLPNVSITNSYGPTEATVEAAFFDCPPQEKLERIPIGKP
                     VHHVRLYILNQNQRMLPVGCIGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYK
                     TGDVARWLPDGNIEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEP
                     ELCAYIEGLQRNEVRAQLERLLPGYMVPAYMIEMKQWPVTPSGKLDRNALPAPGGAADA
                     ETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRITKEFDVQVP
                     LKDVFAHPTVEGLAAVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGY
                     NMPAVLELEGKLNPERMDRAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTV
                     LGERTEQEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIRE
                     FGELYNNRNLPALRIQYKDYAVWQEGFKTRDAYKTQGAYWLKQLEGELPVLDLPADHAR
                     P"
     aSDomain        3710..4600
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.70E-117"
                     /label="ctg12_2_Condensation_DCL.1"
                     /locus_tag="ctg12_2"
                     /protein_end="304"
                     /protein_start="7"
                     /score="383.7"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNPQFFQN
                     SINALVERHDIFRTIFISQNVSSPQQVVLRERNVIVLEENITHLNEAEQSQFIEQWKEK
                     DRDQGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA
                     SPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGKSRQEHVT
                     FSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI
                     EHMVGLFINTMPVRVQ"
     aSModule        3710..6808
                     /complete
                     /domains="nrpspksdomains_ctg12_2_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg12_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg12_2_PCP.1"
                     /locus_tags="ctg12_2"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3719..3760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0001"
                     /evalue="1.10E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg12_2"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.2"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       3782..3895
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0002"
                     /evalue="1.50E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg12_2"
                     /protein_end="69"
                     /protein_start="31"
                     /score="49.4"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNPQFFQNSINALVERHDIFRTIFI"
     CDS_motif       4115..4180
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0003"
                     /evalue="6.10E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg12_2"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.7"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       4226..4264
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0004"
                     /evalue="1.50E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg12_2"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.4"
                     /tool="antismash"
                     /translation="PYGKYIKWLMEQD"
     CDS_motif       4499..4594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0005"
                     /evalue="1.20E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg12_2"
                     /protein_end="302"
                     /protein_start="270"
                     /score="62.7"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTMPVR"
     CDS_motif       4640..4756
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0006"
                     /evalue="2.20E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg12_2"
                     /protein_end="356"
                     /protein_start="317"
                     /score="65.1"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP"
     aSDomain        5093..6283
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_AMP-binding.1"
                     /evalue="5.80E-105"
                     /label="ctg12_2_AMP-binding.1"
                     /locus_tag="ctg12_2"
                     /protein_end="865"
                     /protein_start="468"
                     /score="343.0"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQ
                     EPVAIMMERSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLPS
                     SLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL
                     KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRKRGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTSDKFSSDPFKPDVIMYRTGDLARRLEDGNIEYIGRADNQVKIR"
     CDS_motif       5279..5320
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0007"
                     /evalue="6.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_2"
                     /protein_end="544"
                     /protein_start="530"
                     /score="13.2"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPVD"
     CDS_motif       5504..5560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0008"
                     /evalue="1.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_2"
                     /protein_end="624"
                     /protein_start="605"
                     /score="26.6"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVQFEH"
     CDS_motif       5942..5968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0009"
                     /evalue="5.20E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg12_2"
                     /protein_end="760"
                     /protein_start="751"
                     /score="3.9"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       6077..6166
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0010"
                     /evalue="7.80E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_2"
                     /protein_end="826"
                     /protein_start="796"
                     /score="40.6"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF"
     CDS_motif       6248..6313
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0011"
                     /evalue="7.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_2"
                     /protein_end="875"
                     /protein_start="853"
                     /score="37.1"
                     /tool="antismash"
                     /translation="YIGRADNQVKIRGYRIEPQEIE"
     CDS_motif       6521..6547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0012"
                     /evalue="5.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg12_2"
                     /protein_end="953"
                     /protein_start="944"
                     /score="3.8"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     aSDomain        6602..6808
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_PCP.1"
                     /evalue="1.20E-23"
                     /label="ctg12_2_PCP.1"
                     /locus_tag="ctg12_2"
                     /protein_end="1040"
                     /protein_start="971"
                     /score="75.0"
                     /tool="antismash"
                     /translation="EAKLSQLFEDVLKNGHIGIQDNFFDNGGHSLKATVLMSRIAKEFH
                     VQVSLKDIFAHPTVEGLALIIREA"
     aSDomain        6851..7687
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.30E-101"
                     /label="ctg12_2_Condensation_LCL.1"
                     /locus_tag="ctg12_2"
                     /protein_end="1333"
                     /protein_start="1054"
                     /score="331.4"
                     /tool="antismash"
                     /translation="DTYPVSSAQKRIYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVC
                     KELISRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFCLSQAPLFRAGL
                     IEVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKK
                     GDSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHK
                     NRSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        6851..9901
                     /complete
                     /domains="nrpspksdomains_ctg12_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg12_2_AMP-binding.2"
                     /domains="nrpspksdomains_ctg12_2_PCP.2"
                     /locus_tags="ctg12_2"
                     /monomer_pairings="Glu -> Glu"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       6917..7030
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0013"
                     /evalue="8.20E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg12_2"
                     /protein_end="1114"
                     /protein_start="1076"
                     /score="47.2"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELISRHEPLRTSFV"
     CDS_motif       7202..7267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0014"
                     /evalue="2.10E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg12_2"
                     /protein_end="1193"
                     /protein_start="1171"
                     /score="29.9"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       7298..7330
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0015"
                     /evalue="3.90E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg12_2"
                     /protein_end="1214"
                     /protein_start="1203"
                     /score="13.1"
                     /tool="antismash"
                     /translation="QYKDYAVWQQK"
     CDS_motif       7589..7678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0016"
                     /evalue="3.10E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg12_2"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="51.7"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       7727..7846
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0017"
                     /evalue="7.60E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg12_2"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="66.5"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        8186..9388
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_AMP-binding.2"
                     /evalue="5.10E-113"
                     /label="ctg12_2_AMP-binding.2"
                     /locus_tag="ctg12_2"
                     /protein_end="1900"
                     /protein_start="1499"
                     /score="369.6"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAEKTPDQAAVIFEDGVMTYKELNEQANRIAWELIGRGVKPE
                     TTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSAGLH
                     VPAFTGEIVYLNQTNSGLAHRLSNPNVDVLPQSLAYVIYTSGSTGMPKGVEIEHRSAVN
                     FLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIAKA
                     IEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFYELLPN
                     VSITNSYGPTEATVEAAFFDCPPQEKLERIPIGKPVHHVRLYILNQNQRMLPVGCIGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNIEFLGRTDDQVK
                     IR"
     CDS_motif       8375..8413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0018"
                     /evalue="9.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_2"
                     /protein_end="1575"
                     /protein_start="1562"
                     /score="15.6"
                     /tool="antismash"
                     /translation="GILKAGGAYLPID"
     CDS_motif       8600..8659
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0019"
                     /evalue="1.10E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_2"
                     /protein_end="1657"
                     /protein_start="1637"
                     /score="30.2"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGMPKGVEIEH"
     CDS_motif       9044..9073
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0020"
                     /evalue="5.00E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg12_2"
                     /protein_end="1795"
                     /protein_start="1785"
                     /score="6.8"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       9182..9271
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0021"
                     /evalue="2.10E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_2"
                     /protein_end="1861"
                     /protein_start="1831"
                     /score="58.3"
                     /tool="antismash"
                     /translation="PVGCIGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       9353..9418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0022"
                     /evalue="1.40E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_2"
                     /protein_end="1910"
                     /protein_start="1888"
                     /score="39.4"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
     CDS_motif       9614..9640
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0023"
                     /evalue="5.70E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg12_2"
                     /protein_end="1984"
                     /protein_start="1975"
                     /score="3.7"
                     /tool="antismash"
                     /translation="GKLDRNALP"
     aSDomain        9695..9901
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_PCP.2"
                     /evalue="1.30E-25"
                     /label="ctg12_2_PCP.2"
                     /locus_tag="ctg12_2"
                     /protein_end="2071"
                     /protein_start="2002"
                     /score="81.3"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRITKEFD
                     VQVPLKDVFAHPTVEGLAAVIREG"
     aSDomain        9944..10552
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_Condensation_LCL.2"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.80E-70"
                     /label="ctg12_2_Condensation_LCL.2"
                     /locus_tag="ctg12_2"
                     /protein_end="2288"
                     /protein_start="2085"
                     /score="229.2"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRA
                     FKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQEAAAAFIKPFDLS
                     QAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPALRIQYKDY
                     AVWQEGFKTRDAYKTQGAYWLKQLEGELPVLDLPADHARP"
     CDS_motif       10016..10123
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0024"
                     /evalue="1.20E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg12_2"
                     /protein_end="2145"
                     /protein_start="2109"
                     /score="53.0"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFKELIKRHESLRTSF"
     CDS_motif       10322..10387
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0025"
                     /evalue="8.80E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg12_2"
                     /protein_end="2233"
                     /protein_start="2211"
                     /score="31.1"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       10418..10447
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0026"
                     /evalue="2.20E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg12_2"
                     /protein_end="2253"
                     /protein_start="2243"
                     /score="13.9"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
ORIGIN
        1 acgctggcgc ttcggacgcg tccggagggc gggaagccat tcgtacagta tttgcaggaa
       61 gtgcgtgaga cagcattgga agcctttgag caccaggatt acccgttcga agagcttgtc
      121 gataagcttg aattaacacg ggatatgagc agaaatccgc tgtttgacgt aatgtttgtt
      181 cttcaaaaca tggatcagga atcgttggag ctgaatgaac tttgtctcaa acctgcagca
      241 cacaatgggc atcaaacgtc caaatttgat ttaaccctat atacacagga acagccccgc
      301 ggtttgctga cgttccaaat ggagtttagt actgacttat ataagaaaaa aacgatagaa
      361 aagtggcttc aatacttcat caatatgtta ctctccatca tcaaagacaa caaagccgct
      421 ctcggaacaa taaatatcct gaatgaggat gagacccatt accttatcca cgagctcaat
      481 cgtacaaaaa tagattatcc aagaaatgaa accatcagca gactctttga aatgcaggca
      541 gaacaaacac ctaatgctgt agcaattgtc agcgacaccc aagtattcac ttacgaggac
      601 ctgaacagct gggcaaatca aattgcctca gttctacaga taaagggcgt agggcctgat
      661 agtgttgtag ccttgttgac aggcagaaca ccagaactca ttgcaggaat gctgggcatt
      721 ctgaaagccg ggggagccta tctgcctatt gcttctgatc tgcctgttga acgaatagct
      781 tatatgctgt cagacagcgg ggcggcatta ctccttcaat ctgaaaaaac agaaaaacag
      841 ctattagaca ttgaatgtga acaaatcata atcgaagata ttcaaaagca aggaaaaacg
      901 aagaacgttg attcttcagc agggccacat tcactcgcat atatcattta tacctctgga
      961 tcaaccggta aaccaaaggg tgtcatgatt gagcagcgaa gtgtaattcg tcttgttaaa
     1021 aacagcaatt atattacatt tacacctgaa gaccgccttc tgatgacatc atcaatcggt
     1081 ttcgacgttg ggtcatttga aattttcgga ccgctgctaa atggtgccgc tttgcatctg
     1141 tccgatcaac aaacatttct cgattcccat cagcttaaga ggtacataga acatcaagga
     1201 atcacaacga tttggctgac atcttctcta ttcaatcatt tgacagaaca aaatgaacaa
     1261 acattttcac agctgaaaca tttgattata ggcggagaag ctttgtcgcc gagccacgtc
     1321 aatcgaatca gaaatgtctg ccctgaagta tctatatgga atggatatgg ccctaccgaa
     1381 aatacaactt tttcgacatg ccttcacatt caaaaaacat atgaactttc cattccgatc
     1441 gggcggccgg ttggtaattc caccgcttat atcttaaatc aatggggagt gctgcagccg
     1501 gtcggagctg tcggtgaact ttgtgtcggc ggagatggcg tcgccagagg atatttgggc
     1561 cgtcctgatt taacgaaaga gaaatttgtc ccacatccat ttgcacctgg cgatcgactg
     1621 tatcgcacgg gtgatctggc gcgctggctt cctgatggca caattgagta cgttggccgt
     1681 attgatgatc aagtaaaagt cagaggctat cgggtggagc tgggtgaaat cgaaacagca
     1741 tttcgtcaaa tagacggagt caaagaagcc gcagtgttag cacgtacagc ccagaccggg
     1801 agcaaagagc tgtttggcta tatcagcgta aaagcaggca cgaatgctga acaagtgcgt
     1861 tcacttctcg cgtgttcact gcctaattat atgattccgg cgtatatcat tgaaatggag
     1921 aatcttccgc tcacatcgaa cggcaaattg aaccggaaag cactgcctga accagatttc
     1981 gcatctaaac aaacatacat cccgccacgc aacgaacttg aagagcagct ggcattgatc
     2041 tggcaggagg ttctaggcat ccagaggatc ggaatagagg attcattctt tgaattgggc
     2101 ggcgattcaa tcaaagcgct tcaagtttct gcacgtctcg ggcgccacgg gttaagcttg
     2161 caggtaagtg atttattccg tcgtccaaag ataaaagact tatcaccatt tattcgtaaa
     2221 acagagagag tcatagaaca aggacctgtt cagggagatg ttccatggac gcctattcag
     2281 aaatggtttc tctcacaaga catagaagaa cgacaccatt tcaatcagtc tgtcatgctt
     2341 ttccatactg accgtttgtc tgaagacgct cttagagcat ccttaaaaaa gctggcggag
     2401 catcatgatg cgcttcggat ggtttatcgc aacgatgata ggcgatggat tcaaatcaac
     2461 caaggcattc atgagtcaca gctatacagc ttaagaacct ttgatctttc acagtcagaa
     2521 agcggctggg agacgcaaat caaacaagaa gttgcagatc ttcagcaaag catcaatttg
     2581 caggaaggac cattgttgca cgccgctttg tttaaaacac tgaccggaga ttacttgttc
     2641 cttgcgatcc atcaccttgt cgttgatggt gtctcatggc ggattttgct tgaggatttg
     2701 tcagccggat atcaacaagc tgctgcaggc cagacgatcc agcttccgcc taaaacggat
     2761 tcctatcagg aatacgcaag acgcatacag gaatatgccc aaagcagtaa gctgattcgc
     2821 gaagaggcgt attggcgaac tgtagaagaa cagcaagacg cagaactgcc ctatgaaata
     2881 ccgcatcaag tgaacatcga cttcagcaaa agggactcat taaacttttc actgactgaa
     2941 gcagacaccg ccgtcttgct gcaaaacgtc aatcacgcct atggcacaga tacacaagat
     3001 attctgttaa ccgcagcatc cttggcgatt tgtgaatgga caggaggaag caagctccgt
     3061 atcgctatgg aaggacacgg gagagaacac attctgccag agttagatat cagcaggacg
     3121 gtcggctggt ttacatccat gtatccggcc ctcataagct ttgaaaatca tagggatgag
     3181 ctcggaaccg cattaaaaac cgttaaagat acactgggcc ggataccaaa caaaggggta
     3241 ggttacggta tgctgaaata ccttacacac cctgaaaata aaagcattac gttttcaaaa
     3301 acacctgaaa tcagctttaa ctatttgggc cagttcaacg acatcgaaag acaggacacc
     3361 ttccgcccat caagccttgg gagcggaaag gatatcactc atacatggaa gcgtgagcaa
     3421 atcatcgaga tgagcgcaat ggcagcagac aaaaagctcc atttcaatct tagttatccg
     3481 ccagcccgct ttcacagaaa cacaatggaa cagcttatta acaggattga acactttttg
     3541 ctggacatta tgaaacactg cgccggtcaa cagaaaacag aaaagacact gagcgatttc
     3601 agcagtcaat cattaacggc tgaggacttg gacagcatat ccagcttggt ggaagaattg
     3661 tagaaaatcg tgacagggag acatgaacat gacaaaagcg aattcaattc aggatattta
     3721 tccgctgtct tacatgcagg aagggatgct tttccattcc ctcctgcaaa aagattcaca
     3781 ggcgtatgtt gagcaagctt cttttacaat tgaaggaaaa gtcaacccgc agttttttca
     3841 aaacagcatc aacgctcttg tagaaagaca tgatattttc agaacgattt ttatcagcca
     3901 aaatgtttcc tctccccagc aggttgttct gagagaacga aatgtcatcg tactggaaga
     3961 aaacattact catttaaacg aggcggagca atcacagttt atcgagcaat ggaaagaaaa
     4021 ggaccgggac caggggtttc atttacaaaa ggatgtgctc atgcgcatcg ctctgattca
     4081 aacaggagag agccagtact cttgcatttg gacctttcat catatcatga tggacggttg
     4141 gtgcctcagc attgtgctaa aggagtttct gcatatttac gcatcttatg taaatgcatc
     4201 cccaataaca ttggagccgg tccagccata cggaaagtat atcaaatggc tgatggagca
     4261 agacaaagag caggcggttt cttattggga ccattatctt tccggccacg aacagcaaac
     4321 cgtgctcccg aagcagaaaa aaacaaaggg aaaaagcagg caggaacacg ttacattttc
     4381 attctctaag gaagaaagca gcaggctttc agagcttgct gctagagaag aagtgacact
     4441 cagtacgatt tttcatacca tttggggcat tctgctacaa aaatataata ataacgatga
     4501 cgccgtattc ggttctgtca tttcaggaag acccgcagaa atcgaaggca ttgaacatat
     4561 ggtaggtctt ttcattaata cgatgccggt tcgggtgcag ggggcaaaaa cgccttttct
     4621 tcaacttata aaagatatgc aaaaagaccg tcttgccgct gaagcgtaca gctaccatcc
     4681 tttatatgag attcaatccc gctcagctgt taagcaaggg ctgattgatc atattctcgt
     4741 atttgaaaac tatccggtgc agcaagagat tcaaatgctg aacaaacagg aacatgcttc
     4801 tgatcttttt cagattcata atttcactgt cgcagatgaa accaactaca gcttttatct
     4861 tatggtggcg ccaggggaag aaattcatat caaaatgaac tatgatgcgg agcagcacga
     4921 tcggtctttt gtgctctctg tcaaagagca tcttctgaat gctgtatcac aaatcttaaa
     4981 taatccgaac cttccacctg aagaaatcga tatcacgaca gatactgaaa agcggcagct
     5041 gattggagaa atcacagatc aaacaccagt ttacgaaacc atccatgcca tgtttgaaaa
     5101 gcaagcggaa aagacaccag atgctcatgc tgtaattgat caagcctgct cattaacata
     5161 cagagaactg aataaagcgg ctaacagatt ggcacggcat ttacgaatga aaggcgttgt
     5221 gagacaggaa cccgttgcga ttatgatgga acgctcagcg gcgtttatca caggtgttct
     5281 tggtatcttg aaagcaggcg gcgccattgt tccggttgat ccgcattacc ctgctgacag
     5341 aatccgttat attctgcatg attgcggctg ttcgcatgtt gtttcacaag cgcatcttcc
     5401 ctcatcgtta gaagacaatt acattatcac tcatccagaa gatatcgaaa gcaaagtaga
     5461 cggcagtaac ataaagtcag tcaacaatgc tgacgatctg ctgtatatga tttatacatc
     5521 aggcacaaca ggtaaaccaa agggtgttca atttgagcat cgaaacatgg ctaacttgct
     5581 gaagttcgaa tatactcact ccggcattga ctttgaagca gatgttctgc aatttgcgac
     5641 gccttccttc gacgtctgct atcaagaaat attttctgcg cttctgaaag gcggcacact
     5701 ccacatcgtg ccagaagcca taaaaagaga tgtgcctcag ctgtttgcat ttataaacaa
     5761 gcatcagacg aatattgtgt ttctcccaac tgcttttatc aaaatgattt tcagcgagcg
     5821 agaacttgcg aactcgtttc ctgatggcgt caaacacctg atcgcagccg gggaacaatt
     5881 aatgatttca gaccttttcc aagatgtgtt gcgtaaacgc ggcatacacc tgcacaatca
     5941 ttacggacct tcagaaactc atgtggtatc tacgtatacc attcatcctg gagaccctat
     6001 tcctgagctt ccgccaatcg gtaaaccgat aggctgtact gatctatata ttttgaatca
     6061 tcaaaaacag cttcagccat gcggcgtacc aggcgaactc tatatttccg gcgcaagtgt
     6121 tgccagagga tatgtcaatc acgataaact gacaagcgac aaattttcat ccgatccatt
     6181 caagcctgat gtgatcatgt accggacagg tgatttggcc agacggcttg aagacggcaa
     6241 catcgaatat atcggacggg cagacaatca agtgaaaatc agaggttatc gaattgagcc
     6301 gcaagaaatc gaagtcacgc taatgaatca tccggacatt agtgaggctg ccattctcat
     6361 ctggcaagat caaaacggtg aacatgaatt atgcgcttac tattgcagtg tacaaaagct
     6421 gaatgcaata gatttacgca gttatatggc tagtgagctc ccagaataca tgattccgtc
     6481 gaaatggata tgggttgaca gcatacctct taccccaaac ggaaaagtag atcgcgcagc
     6541 acttccggag ccagatgctt caatcagcgg aaacccatat accgcccctc gaaatctgtt
     6601 agaggcaaag ctttcgcaac tatttgaaga tgtgctaaag aatggacata taggcatcca
     6661 agacaacttt tttgacaatg gcggccactc gttaaaagca acagtgctta tgtcacggat
     6721 cgcaaaggaa ttccatgtgc aagtttcact taaggacatc tttgctcatc cgactgttga
     6781 aggattagct ttaattattc gagaggctga acaaaatctg tatgcagcaa ttgaaccagc
     6841 agaagaaagg gatacatatc ctgtatcttc ggcccaaaaa cgaatctatg tgcttcaaca
     6901 gcttgatgag ggtgtcgcct ataacatgcc tgcggtctta gaactggaag gtgcactgga
     6961 tgtcgccaaa ctgtctgctg tatgtaaaga actgatcagc cggcatgagc cgcttcgaac
     7021 ttcctttgta tccggagctg atgacgagcc ggttcagcgt atccacaccg aagtgccgtt
     7081 tacgttaagt aaagagacca ctatcgaggg atttgtccgt cccttttgtc tcagccaggc
     7141 gccattattt agagcaggcc ttatagaagt gtcaaacgag aagcatgtat tgctggtgga
     7201 tatgcaccat atcatttcag atggcgtatc cgttcagctc ctaatccgag aatttaccga
     7261 tctttatgca aaccggcagc ttaagccatt gcggatccaa tataaagatt acgccgtatg
     7321 gcagcagaaa tttaaaaagg gagactcgta ccaaaagcag gagacttact ggcagcagca
     7381 gtttagcggg gaccttccta tactggagct tccaacagat aaacgacgtc cggcagaacg
     7441 gcaattcata ggcggaaaag taacctttca attggacaaa gagatcacgg cccgcataaa
     7501 gcggctcgcc cataaaaaca gaagcacgct ttatatgacg cttctcgctt tgtattcagc
     7561 ctttttgtct cggttaagcg gtcaggatga tatcgtgatt ggttcaccta tcgccggacg
     7621 gccccatgcc gaccttgaag ctgttcttgg gatgttcgtc aatacattgg ctctccgcac
     7681 acgcccggcg ggtaataaga catttgagga atttctgaaa gaagtcagac agacggcact
     7741 agaagcgtat gagcatcagg attacccgtt tgaagagctt gtggacaaac tcggtgtgca
     7801 gcgggaaatg agccggaatc ctttgtttga cacaacgcta gtccttcaga atatggaaca
     7861 gcaaaagcta aaaatgaatg atgtacagct tcagtggaac gacttggagc acccaatatc
     7921 aaaatttgat atttccctat acgttacaga gcatgattcc gagcttttct gtcagtttga
     7981 atacagtaca gctttgtttg agaaagaaac catccaaagg tgggccagcc ttttcaccac
     8041 gcttgtggaa catacagctg ccagtcctga aacagaattg gacaatattc caatcttaac
     8101 aaaagaagaa gagcgagatt tcattgaatc atgccatctg tttgaggaga cgggctattc
     8161 aatgaatcaa acgctccact atgcactcga acagcaggca gaaaaaacgc ctgatcaggc
     8221 ggccgttatc ttcgaagatg gagtgatgac ctataaagaa ttgaacgaac aggctaaccg
     8281 tatcgcctgg gagctgatcg gacggggggt aaaacctgaa acgactgttg ccattatagg
     8341 aaagcgttca cctgaaatgc tgcttggcat ttatggcatt cttaaagctg gcggcgctta
     8401 tctgcccatc gacccggatt atccggaaga acgaatcagc tttctgctgg aggacagcgg
     8461 tacaaacatt ctcctgcttc agtctgccgg ccttcatgtt ccggcattta caggagagat
     8521 tgtctatctc aatcagacaa atagcggact ggcacatcgt ttgtccaatc cgaatgtgga
     8581 tgttctcccg caatctttag cctatgtcat ctatacatcc ggctctaccg ggatgcctaa
     8641 gggtgttgaa attgaacatc gatcagcggt gaattttttg aattccctac agtcccgcta
     8701 tcagctaaag cattcagata tgattatgca caaaacatca tattcattcg atgcttcaat
     8761 atgggagctg ttttggtggc cttatgccgg agcttctgtt tatctgcttc ctcagggagg
     8821 cgaaaaagaa cctgaagtga tcgcgaaggc catagaagaa caaaagatca cagctatgca
     8881 ttttgtgcct tcaatgctcc atgcattttt agaacatata aaatatcgct ctgtaccgat
     8941 taagacaaac agactcaagc gagtgttttc tgggggagaa cagctgggga cccatcttgt
     9001 ctcccgattt tacgagttgc ttccaaatgt ttcaataacc aattcctatg ggccaacgga
     9061 agcaaccgta gaagctgcat tctttgattg tccgccacaa gaaaaacttg aacggattcc
     9121 aattggaaaa cctgttcatc atgtcagatt atatatcctg aatcagaatc agcggatgct
     9181 gcctgttgga tgtatcggtg aactatacat tgccggagcg ggtgttgcca gaggttattt
     9241 gaatcggccg gcattaacgg aggagcgttt tcttgaagac ccgttttacc cgggggaacg
     9301 catgtacaaa accggggatg tggcgcgctg gctccctgac gggaatattg aattcctcgg
     9361 gcgcacggat gatcaggtga aaatccgcgg ctaccggatt gagccgggag aaattgaagc
     9421 ggcactaaga agcatagaag gtgtaagaga ggcggccgtt accgtacgga cagacagcgg
     9481 ggagccggaa ttatgcgctt atatagaagg gctccaaaga aacgaagtcc gagcgcagct
     9541 tgagagactg ttgccgggct acatggtccc agcctatatg atagaaatga aacagtggcc
     9601 ggttacgcca agcggaaagc tcgaccgaaa cgccctgcca gctcctggcg gagcggcaga
     9661 tgcggagacc tacacagcgc cgagaaacgt gactgagatg aagctttctc agctgtggga
     9721 ggacgtgctg aaaaatggcc ctgtcgggat tcacgacaac ttttttgacc gcgggggaca
     9781 ttccttaaaa gcaacggcgc ttgtctcacg gatcaccaaa gaattcgatg tacaggtgcc
     9841 gctaaaagat gtgtttgccc atccaacagt agaagggctg gctgccgtta tccgtgaagg
     9901 aacggacagt ccatatgaag cgattaagcc cgctgaaaaa caggaaacct atccggtttc
     9961 ctctgcccaa aagcggattt atgtccttca gcagctggaa gacggaggga caggctacaa
    10021 tatgccggct gtgttagagc tcgaagggaa gctcaaccct gaaaggatgg acagagcttt
    10081 caaagagctg atcaagcgcc acgagtcgct tcgtacctcc ttcgaacagg acgcaggagg
    10141 cgatccggtg cagcgcatcc atgacgaggt gccgtttacg ttacagacta cagttctcgg
    10201 cgaacgaacc gaacaggagg ccgcagccgc atttatcaaa ccgtttgatc tcagccaagc
    10261 gccgctgttc cgtgcccaaa tcgtaaaggt atcagatgag cggcacctgt tgctggttga
    10321 tatgcatcac atcatttcag acggtgtttc cgtcaacatt ctgattcggg aattcggcga
    10381 gctgtacaat aatcggaatc ttcctgcgct gcgcattcaa tataaagact acgccgtatg
    10441 gcaagaagga ttcaaaacaa gagacgcgta caaaacgcag ggggcgtact ggctgaagca
    10501 gctcgagggc gagctgcctg tgctggatct tccggctgat catgcccgcc cgcc
//
