LOCUS       gnlProkkaAJLADPGO_22    2257 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJLADPGO_22.
ACCESSION   gnlProkkaAJLADPGO_22
VERSION     gnlProkkaAJLADPGO_22
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:09:47
            Original ID  :: gnl|Prokka|AJLADPGO_22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2257
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2257
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:2255]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2255
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..2257
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2257
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             3..2255
                     /NRPS_PKS="Domain: AMP-binding (1-363). E-value: 2.8e-100.
                     Score: 327.6. Matches aSDomain:
                     nrpspksdomains_ctg22_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (465-534). E-value: 3.8e-26. Score:
                     83.0. Matches aSDomain: nrpspksdomains_ctg22_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (548-751). E-value:
                     1.8e-70. Score: 229.2. Matches aSDomain:
                     nrpspksdomains_ctg22_1_Condensation_LCL.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     326.3; E-value: 4.6e-99)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_1"
                     /sec_met_domain="AMP-binding (E-value: 5.4e-118, bitscore:
                     380.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-18, bitscore:
                     53.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 6.8e-69, bitscore:
                     218.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKER
                     LSYMLKDSGASLLLTQPGCSAPNFSGETLEVDMTSLASEKAENHLFTPADGGSLAYVIY
                     TSGSTGQPKGVAVEHRQAVSFLTGMQYQFPLSEDDIVMVKTSFSFDASVWQLFWWALSG
                     ASAYLLPPGWEKDSALIVQAIHQEKVTTAHFIPAMLNSFLDQAEIERLRDSTSLKRVFA
                     GGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPG
                     ARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFPEDPFYPGERMYKTGD
                     VARWLPDGNIEFLGRLDDQVKIRGYRIEPGEIEAALRSVEGVREAAVTVRTGSGEPELC
                     AYIEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGVAADAETY
                     TAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKD
                     VFAHPTVEGLAAVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMP
                     AVLELEGKLNPERMGRAFKELIKRHESLRTAFEQDAGGDPVQRIHDEVPFTLQTTVLGA
                     RTEEEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGE
                     LYNNRKLPALRIQYKDYAVWQEGFKTGDAYKTQEVYWLKQLEGELPVLDLPADHARP"
     aSDomain        6..1091
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_1_AMP-binding.1"
                     /evalue="2.80E-100"
                     /label="ctg22_1_AMP-binding.1"
                     /locus_tag="ctg22_1"
                     /protein_end="363"
                     /protein_start="1"
                     /score="327.6"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="RGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERL
                     SYMLKDSGASLLLTQPGCSAPNFSGETLEVDMTSLASEKAENHLFTPADGGSLAYVIYT
                     SGSTGQPKGVAVEHRQAVSFLTGMQYQFPLSEDDIVMVKTSFSFDASVWQLFWWALSGA
                     SAYLLPPGWEKDSALIVQAIHQEKVTTAHFIPAMLNSFLDQAEIERLRDSTSLKRVFAG
                     GEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGA
                     RLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFPEDPFYPGERMYKTGDV
                     ARWLPDGNIEFLGRLDDQVKIR"
     aSModule        6..1604
                     /complete
                     /domains="nrpspksdomains_ctg22_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg22_1_PCP.1"
                     /locus_tags="ctg22_1"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       75..116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0001"
                     /evalue="4.40E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg22_1"
                     /protein_end="38"
                     /protein_start="24"
                     /score="19.7"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       300..359
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0002"
                     /evalue="3.00E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg22_1"
                     /protein_end="119"
                     /protein_start="99"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       885..974
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0003"
                     /evalue="4.30E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg22_1"
                     /protein_end="324"
                     /protein_start="294"
                     /score="57.3"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       1056..1121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0004"
                     /evalue="3.70E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg22_1"
                     /protein_end="373"
                     /protein_start="351"
                     /score="41.2"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     aSDomain        1398..1604
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_1_PCP.1"
                     /evalue="3.80E-26"
                     /label="ctg22_1_PCP.1"
                     /locus_tag="ctg22_1"
                     /protein_end="534"
                     /protein_start="465"
                     /score="83.0"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFD
                     VQVPLKDVFAHPTVEGLAAVIREG"
     aSDomain        1647..2255
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.80E-70"
                     /label="ctg22_1_Condensation_LCL.1"
                     /locus_tag="ctg22_1"
                     /protein_end="751"
                     /protein_start="548"
                     /score="229.2"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMGRA
                     FKELIKRHESLRTAFEQDAGGDPVQRIHDEVPFTLQTTVLGARTEEEAAAAFIKPFDLS
                     QAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRKLPALRIQYKDY
                     AVWQEGFKTGDAYKTQEVYWLKQLEGELPVLDLPADHARP"
     CDS_motif       1719..1826
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0005"
                     /evalue="4.70E-17"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg22_1"
                     /protein_end="608"
                     /protein_start="572"
                     /score="54.4"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMGRAFKELIKRHESLRTAF"
     CDS_motif       2025..2090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0006"
                     /evalue="2.60E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg22_1"
                     /protein_end="696"
                     /protein_start="674"
                     /score="32.8"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       2121..2150
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg22_1_0007"
                     /evalue="6.50E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg22_1"
                     /protein_end="716"
                     /protein_start="706"
                     /score="15.5"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
ORIGIN
        1 cggcacgcgg cgtcacaaac gaaagtatcg tcggtgtcct gtctgaacgc tcacctgaca
       61 tgctgatcgc tgtccttgct gtattgaagg ccggaggggc gtatttgccg cttgatcctg
      121 cgtatccaaa ggagcggctg agctacatgc tgaaagacag cggggcatcg ctcttgctga
      181 cacagccggg atgctccgca ccaaactttt ctggcgaaac gcttgaagtg gacatgacat
      241 ctcttgcgag cgaaaaagca gaaaaccatc tgtttactcc tgctgacggc ggttctctcg
      301 cctatgtcat ctatacatcg ggctctaccg ggcagccgaa aggagtggcc gttgagcacc
      361 gccaggctgt ttcttttctg accggcatgc agtaccagtt tccgctttca gaagatgaca
      421 ttgtcatggt gaaaacctct ttttcctttg atgcgtctgt gtggcagctg ttttggtggg
      481 ctctttccgg tgcttcggcg tatctgcttc cgcccggctg ggaaaaagac tccgcattga
      541 tcgtacaagc cattcatcag gaaaaagtga caacggctca ttttattccg gctatgctga
      601 acagctttct ggatcaagcg gaaatcgaaa ggttgcgtga cagcacaagc ctgaaacgtg
      661 tattcgccgg aggtgaaccg cttgcgccgc gtacggcagc ccgttttgct tctgtattgc
      721 cgcaggtatc attaatccat ggctacgggc cgacagaagc aacggtagac gcggcatttt
      781 acgtgttaga tccagaacgg gacagggatc gtttgcggat tccgattggg aagcccgtac
      841 ctggtgcgcg tttgtatgtt ttagatccgc atttagccgt acagccttcc ggtgtcgccg
      901 gcgaactgta cattgccgga gcgggtgttg ccagaggtta tttgaatcgg ccggcattga
      961 cggaggagcg ttttcctgaa gacccgtttt acccgggtga acgcatgtac aaaaccgggg
     1021 atgtggcgcg ctggctccct gacgggaata ttgaattcct cgggcggttg gatgatcagg
     1081 tgaaaatccg cggctaccgg attgagccgg gagaaattga agcggcacta agaagcgttg
     1141 aaggcgtaag agaggcggct gttaccgtac ggacaggcag cggggagccg gaattatgcg
     1201 cttatataga agggctccaa agaaacgaag tgcgggcaca gcttgagaga ctgttgccgg
     1261 gctacatggt cccagcctat atgatagaga tggaacagtg gccggttacg ccaagcggaa
     1321 agctcgaccg aaacgccctg ccagctcctg gcgtagcggc agatgcggag acctacacag
     1381 cgccgagaaa cgtgactgag atgaagcttt ctcagctgtg ggaggacgtg ctgaaaaatg
     1441 gccctgtcgg gattcacgac aacttttttg accgcggggg gcattcctta aaagcaacag
     1501 cgcttgtctc acggatcgcc aaagaattcg atgtacaggt gccgctaaaa gatgtgtttg
     1561 cccatccgac ggtagaagga ctggctgccg ttatccgtga aggaacggac agtccatatg
     1621 aagcgattaa gcccgctgaa aaacaggaaa cctatccggt ttcctctgcc caaaagcgga
     1681 tttatgtcct tcagcagctg gaggacggag ggacaggcta caatatgccg gctgtgttag
     1741 agctcgaagg gaagctcaac cctgaaagga tgggcagagc tttcaaagag ctgatcaagc
     1801 gccacgagtc gcttcgaacc gccttcgaac aggacgcagg aggcgatccg gtgcagcgca
     1861 tccatgacga ggtgccgttt acgttacaga ctacagttct cggcgcacga accgaagagg
     1921 aggccgcagc cgcatttatc aaaccgtttg atctcagcca agcgccgctg ttccgtgctc
     1981 aaatcgtaaa ggtatcagat gagcggcacc tgttgctggt tgatatgcat cacatcattt
     2041 cagacggtgt ttccgtcaac attctgattc gggaattcgg cgagctgtac aataatcgga
     2101 agcttccggc actgcgcatt caatataaag attatgccgt atggcaagaa ggatttaaaa
     2161 caggagatgc gtacaaaacg caagaggtgt actggctgaa gcagctcgag ggcgagctgc
     2221 ctgtgctgga tctccccgct gatcatgccc gcccgcc
//
