LOCUS       gnlProkkaIAPDHHHN_1    23230 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IAPDHHHN_1.
ACCESSION   gnlProkkaIAPDHHHN_1
VERSION     gnlProkkaIAPDHHHN_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:09:16
            Original ID  :: gnl|Prokka|IAPDHHHN_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 929280
            Orig. end    :: 952510
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23230
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13230]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13230
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23230
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23230
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="4"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(276..1172)
                     /locus_tag="ctg1_955"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFSIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENISKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAIVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDAVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
     CDS             1306..1845
                     /locus_tag="ctg1_956"
                     /transl_table=11
                     /translation="MTAQDRRITKTRKAIYQAFLYLLNQKDYEAITVQEIIDLADVGRS
                     TFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKNQDHVTSLLLSKN
                     DYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVITNFIETLTWWLKKGKSYSE
                     QEVVQFYLEILNVASN"
     CDS             1884..2096
                     /locus_tag="ctg1_957"
                     /transl_table=11
                     /translation="MLLLILLGIFTAFLSLAFALLHLMASLSELRKHKNTLGNRLLLIG
                     SNLATFSHPLLPFADCCFIPLADRS"
     CDS             complement(2273..2995)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     76.2; E-value: 4.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_958"
                     /transl_table=11
                     /translation="MRGRVSSYLADFSKLDNVYRFVEEIKRDFQRIDILFNNAGLYAGK
                     ERKASGENVELTFMLSVLVPYIFITELIPLLEKLPDGLVINTSSYMHHFAKVKDLDFGF
                     EKEYNPGLAYNNSKLYTIWMTRYLARDFFLKGSNTTINAYHLGLILTNLGNNSSDKKTE
                     KSLFGRLMKSLSKDLDQGIETGYYLTLSEEVSGLTGYYFDEKKVKSVSEKGYSFEKTQK
                     LMNYCQEKVKMFKEKQNV"
     CDS             3247..3990
                     /locus_tag="ctg1_959"
                     /transl_table=11
                     /translation="MTEKGIIISEKLADLAGISVGDEVTVQNSQDKDIKLKVAGISEMY
                     MGHFIFMNESTYKDAFGKEASQNATILTLKDHSDKNVEQTASRFMSLDGVKGDVQNTTL
                     KAQIKTIVNSLSRVMGVLIDVSILLAFVVLFNLTNINVAERIRELSTIKVLGFFNKEVT
                     LYIYRETIYLSIIGILVEFGLGLGLHQYMVDVIPPENIMFNPNLGWLIYAVPTLVIIII
                     LTGLGIFVNQHLKKVNMLEALKFVE"
     CDS             4110..5480
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 412.7; E-value: 2.5e-125)"
                     /gene_kind="other"
                     /locus_tag="ctg1_960"
                     /transl_table=11
                     /translation="MRLIKNNTELIGIKDQNIKISLVFETDTHIEIQAKLDYPAPSCPH
                     CHGKMIKYDFQKNSKISLLEQAGTPTLLRLKKRRFQCKSCRRVTVAETSIVEKNCQISN
                     LVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKKHYDKLPAVMSWDEFGFKK
                     GELAFVAQNYETNELITILDNRRQTTIRNYFLKYPLKVRQQVQFITMDMSGAYIPLARK
                     LFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRLFQKDSRKLSL
                     NSFYSKTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHFQEKRVDEFFELIEENRS
                     KVNHYFQTVFRTFLRHKQYIKNALETDYSNAKLKATNKLIKDIKRLGFGFRNFINFKKR
                     VFITLNIHKKGPIRSSLDVSFSLPTTVDKETVSYLYAYSALVISLRISSTLNLAKRY"
     CDS             complement(5417..6136)
                     /locus_tag="ctg1_961"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(6152..7828)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 502.8;
                     E-value: 2.1e-152)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_962"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-50, bitscore:
                     168.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.3e-45, bitscore:
                     149.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYRDNIKLGETILPDEFY"
     CDS             complement(8082..9254)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_963"
                     /transl_table=11
                     /translation="MKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             complement(9261..10004)
                     /locus_tag="ctg1_964"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREEAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             complement(10001..11218)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_965"
                     /sec_met_domain="Streptide_RRE (E-value: 5.9e-15, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-20, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.3e-09, bitscore: 32.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.7e-10, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.3e-08, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             complement(11301..11453)
                     /locus_tag="ctg1_966"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEEVVSSGLSIDIMEIKPSVATELIDGLKGR
                     CPPSV"
     CDS             complement(11513..12313)
                     /locus_tag="ctg1_967"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             complement(12373..13230)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_968"
                     /sec_met_domain="TIGR01716 (E-value: 1.5e-43, bitscore:
                     145.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDSLYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCIAAIKLANSENLAIKFENHLSG
                     VLKM"
     CDS             complement(13753..15585)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 549.8; E-value:
                     1.4e-166)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_969"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDTIEEPYIKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             complement(15973..16119)
                     /locus_tag="ctg1_970"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             complement(16395..16736)
                     /NRPS_PKS="Domain: PKS_KR (3-112). E-value: 5.7e-11. Score:
                     34.5. Matches aSDomain: nrpspksdomains_ctg1_971_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     110.3; E-value: 1.8e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_971"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLDTITEEQFQRT
                     FNINVGGVI"
     aSDomain        complement(16401..16727)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_971_PKS_KR.1"
                     /evalue="5.70E-11"
                     /label="ctg1_971_PKS_KR.1"
                     /locus_tag="ctg1_971"
                     /protein_end="112"
                     /protein_start="3"
                     /score="34.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLDTITEEQFQRTFNI
                     NVGGV"
     CDS             complement(16947..17240)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 59.2;
                     E-value: 5.6e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_972"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDDSIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             complement(17242..17670)
                     /locus_tag="ctg1_973"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             17823..17978
                     /locus_tag="ctg1_974"
                     /transl_table=11
                     /translation="MTKSKFQLVGSLLRPADLRKYKDEIEHRDDIQYPFYDALPGYQET
                     ETASIK"
     CDS             17975..18772
                     /locus_tag="ctg1_975"
                     /transl_table=11
                     /translation="MNVADQKANGIDILTDGEFGRSMWHLDFVWGLKGIERYIAEHGYT
                     FKDHDGGQYETRKDIGIRVTEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHTYTE
                     LAIFDQLAVPGQVYETNEELKKGLINVYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPA
                     SFYSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSAAEGTYEDIAK
                     KFLAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(19037..20380)
                     /locus_tag="ctg1_976"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERSLKDLQTFIDA"
     CDS             complement(20481..21875)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 125.7; E-value: 4.8e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_977"
                     /transl_table=11
                     /translation="MALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     LIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDTYVKELSEINKMSLKKTLTLEEVPAKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRHSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             complement(21866..22525)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 178.6; E-value: 2.2e-54)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_978"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDIMMPDVEGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
ORIGIN
        1 agtggagttc caccaattcg gaggtaattg tcatgtaaag tctgaatttt atgtggttca
       61 ggacgaacac cacgccgtat attcgtgaaa aactccgcta ctccttcata ggtaatctct
      121 tctggtgacc caaaggtcat catcaacaca gctctcttac tcataattaa tccttgttct
      181 acatttgttc tattttatca tgaaaaggat cactttaggg aacttggtat caaaataact
      241 cttaaaggta gactctaaga gtttaaaaac aaaccttaat gatggtgttg ctgctcactt
      301 tctgcttcta gctcttcgat atttcgcttg tgagcttggt gggttgccaa gtcttcatca
      361 acttcgatgg tgacattttg aaagccactc tctttgagca agtctcggat agactcttta
      421 cagacctcga tatgtttgac atgctccaga caaacatgga caatagcatt tttctccaag
      481 ccgtccatgg tccaaagatt aagctgattg atactagcaa cattatccaa ctgctctaag
      541 tcattcttaa cttgcttgat atctacccct tctggcacag catccaggaa aatcttgagc
      601 gtgctccaaa aacgtggaat ggctttggac agaataaaga aggaaatagc aagagacaag
      661 aggggatcta ggatatacca gtccgtaaat cggaggacaa tggccatcag gatgacagcc
      721 aaccaaccta aggtatcttc caaaaaatgc aggctgagaa tagactcatt cttggtctga
      781 cccttacgaa tgaccagact agccagcaga ttgacactga tagcaataat tcccaaccaa
      841 agaagccctt cgtcattgac gggttgtggg tggaaaagct tgcttatatt ttctaaaatc
      901 accataccag accctgtcat cagaatgact gccgttacca aagcccctaa taagctaaaa
      961 cgcttgtagc ctagggtata gcgactatct tcttcacgat tggagattgt ttctagaaag
     1021 gccgagaggc caatggctag agcatccccc aagtcatgga cagagtcagc gagaacagca
     1081 ctggaaacaa agattccccc tgcaataaac tcaacaatgg aaaagcttag attcaagaaa
     1141 aaagccaacc agactgcata ttttgaactc attttttacc ttcctttggt ataatagatt
     1201 cacgaacatc atattcaata tctattatcc aatactacca acagaaagga taggggcaaa
     1261 ccgttcgctg tgtacgttac tgaacagttt gttcatagtg tccatatgac tgcacaagat
     1321 cgtcgcatta ccaagactag aaaagccatc tatcaagctt tcttgtactt acttaaccaa
     1381 aaagattatg aggccatcac cgttcaggag attattgact tggctgatgt ggggcgttcg
     1441 accttttaca gccattatga gagcaaagag ttactactgg atgagctctg ccaaaagctc
     1501 tttcaccatt tgtttgagcg tactcaatac ctctctccac aagactacct ggcccatatc
     1561 tttcaacatt tcaagaaaaa tcaagaccat gtaaccagtc tcttgctttc aaaaaacgat
     1621 tattttatcc ggcagctgcg aaaagaactg gaacatgacg tctatccaat ggtagctgat
     1681 gaactgattc aatcacaccc caacattcct cactcatatc tcaagcacct ggttataacc
     1741 aacttcattg aaaccctgac ctggtggttg aaaaaaggca agtcctacag cgagcaggaa
     1801 gtagtccagt tttatttgga gattttaaac gtcgcttcta actaaggtgc gactttacat
     1861 catgtatcat agaaaggaaa actatgctcc ttctcattct tcttggtatt ttcacagctt
     1921 tcttatccct tgcttttgct cttcttcatt taatggccag tctttcagaa ttaagaaagc
     1981 acaagaatac tctaggaaat cggcttctcc ttatcggaag caaccttgcg accttctctc
     2041 atcctttact tccttttgcc gattgttgct ttattccttt ggctgatcgg agttagcttg
     2101 atttgctacg gagcctattg gaatggcaag cataaaggaa atttccatct agtagcccac
     2161 tacctgattc ggatcggaat cgctctggta attacgattt tattaactct tgtataagaa
     2221 aagatcaagt tttattaatg aaaacttgag cttttttctt atatttatga tattaaacat
     2281 tctgcttttc tttaaacatt ttgacctttt cttggcagta attcattaat ttctgtgttt
     2341 tttcaaatga gtagcctttt tcagataccg acttgacttt cttttcatca aagtagtagc
     2401 cagtcaagcc actgacttcc tctgataagg tgagataata gcctgtttcg attccctgat
     2461 ctagatcttt tgaaagagac ttcatcaagc gtccgaagag agacttttcc gtctttttat
     2521 cactagaatt attccctaag ttggttaaaa tcaagccgag atggtaggca ttaatagtgg
     2581 tatttgaacc ttttaaaaag aaatctcttg ctagatagcg tgtcatccaa atggtgtaga
     2641 gcttggaatt attgtaggcc aaaccgggat tgtattcttt ctcaaagcca aagtccaaat
     2701 ccttcacttt cgcaaaatgg tgcatatagg aagaggtatt gataacaagg ccatcaggca
     2761 atttttctaa caaggggatt agctctgtta taaaaatata gggaaccaga acggataaca
     2821 tgaaagttag ttcgacattt tcaccactcg cttttcgctc tttccctgca tacagacctg
     2881 cattgttaaa taagatatca atcctttgaa agtctcgctt gatttcctcc acaaatcgat
     2941 aaacattatc taattttgaa aaatcagcca agtagctaga cactctgcct ctcaaggaga
     3001 ctgcccgaac ctcctgagta gccaattcca gcttttgagg attgcgaccg tggaggatga
     3061 tatgatagcc ttcactagac ggtttctttg ctagatgctt accgataccg tccgtagcac
     3121 ctgttagatg taggaagtaa taacgatcgt caagatatca caacacttgt tgtcaatgat
     3181 aaagatcaaa aaacacttca aaattacatc aaactcaatc atcgtgaaac tggtcagaag
     3241 cttgatttga ctgaaaaagg cattattatc tcagagaaat tggcggacct agctggtatt
     3301 tctgtaggtg atgaagtaac cgttcaaaat agccaggaca aagacatcaa actcaaagtt
     3361 gctggtattt ctgagatgta catggggcac ttcatcttta tgaacgaatc tacttataag
     3421 gatgctttcg gaaaagaggc tagccaaaat gctacgatac ttacactgaa agatcattca
     3481 gacaaaaatg ttgagcaaac agccagtcga tttatgtctc ttgatggtgt aaaaggggat
     3541 gtccaaaata ctactctaaa ggcacaaatc aagaccatcg tcaactcact tagccgtgtt
     3601 atgggagttt tgattgatgt ttctattctt cttgcttttg ttgttctctt caatttaacg
     3661 aatatcaatg tggcagagcg tatccgcgaa ttatcaacca ttaaggttct aggtttcttt
     3721 aataaagaag tgacgctcta catctatcga gaaacaattt atctttctat cattggtatc
     3781 ttggttgaat tcggacttgg tttgggactg catcaataca tggtagatgt tatcccacct
     3841 gaaaatatta tgttcaatcc aaatcttggc tggctcatct acgctgttcc aacactagta
     3901 atcattatca ttctgacagg tctgggtatc tttgtgaacc aacaccttaa gaaagtcaat
     3961 atgctcgagg ctctaaaatt tgttgagtga gatatgctat aacttaataa ataaaactac
     4021 tgtagggatt atagagcttt ttgagtgtac acaaaaagtc ccataagaac tataatgaaa
     4081 agcgaccaaa ccatcattag gaagaactta tgagacttat taagaataac acagaattaa
     4141 tcggaatcaa agaccaaaat atcaagattt cacttgtttt tgaaactgac actcatatcg
     4201 agattcaagc aaaacttgat taccctgcac catcatgtcc tcattgccat ggaaagatga
     4261 ttaagtatga ctttcaaaaa aactctaaaa tctctcttct cgagcaagcg ggaacaccaa
     4321 ctctactacg tctgaaaaaa cgtcgtttcc agtgtaaaag ttgtagaaga gtcacggtag
     4381 ctgagacatc tatcgttgag aaaaactgcc aaatctccaa tctagtccga caaaaagtta
     4441 cacaactcct aactgagaaa gtgtcactaa ctgatattgc aagaagactt cgcgtgtcga
     4501 cgtccactgt ctatcgtaag cttgatcagt tcactttcaa gaaacattat gacaaactcc
     4561 ctgctgttat gtcctgggat gagtttgggt tcaagaaagg ggaattggct tttgtggcgc
     4621 agaattatga gacaaacgaa ctcataacca tccttgataa tcgccgccaa actactatac
     4681 gaaactactt tttgaagtat ccattgaaag tccgacaaca ggtacagttt atcacgatgg
     4741 atatgtctgg agcttatatt ccactggctc gcaagctctt tccaaacgca aaaatcgttc
     4801 ttgatcgttt ccacatcatc cagcaccttg gacgtgcctt tttaaagaca agaattgcaa
     4861 ttatgaacca gttcgataag aagtcactac cctatcgagc cttgaaaaat cactggcgac
     4921 tcttccaaaa ggacagccgt aaactatctc tcaactcttt ttattcaaag actttccgcc
     4981 aaactttagc accacatgaa gttgttgcga agacactagt cttttcaaaa gagcttactg
     5041 actactatac actttatcag cttttgcttt ttcactttca ggagaagaga gtagatgagt
     5101 tctttgaact gatagaggaa aataggagca aggtcaatca ttattttcaa actgtcttta
     5161 ggacttttct tagacacaag caatacatca aaaacgcact agaaacggac tattcaaacg
     5221 cgaaacttaa agctactaat aagttgatca aagacatcaa acgtttgggc ttcggtttta
     5281 gaaactttat caactttaag aagcgtgtct tcatcacact gaacatacat aaaaaaggac
     5341 ctatccggtc ctctctagat gttagctttt cgttacccac tacagttgac aaagagacag
     5401 tatcttattt atatgcttat tcagccttag taatatcttt acgcatttca tcaacattga
     5461 atttagcaaa gagatattga cggtcttgaa ctgggaagcg ttgatcgagt tggtcaactg
     5521 gtccaacttc aataatacca ttctcgataa caaaatccat aacgtgacca ccgaatgtca
     5581 agtcatctga aataaaatgg agatggtaac cagcaacact cacaccgtgg aacatttcag
     5641 gtgtccagat accaacgatt gtacctgaaa tatcatctac ctcatactca ggttggcgag
     5701 tggcaacatc agcaaactta atgtccgcat ttgattttgg aatcatgcgc acgtgcatgt
     5761 gtttaaaatg acctttgatt ttgattgaac ggaaaagatt gaccccatca tagtatgatt
     5821 caatacgatc ctcaagttct ttatcagtca tttcataacg ttgacggaag ataacttcag
     5881 cttggtgagg tacgactgct gcatagggaa ctttttcatc aggagagact tctaccactt
     5941 cgactttacc ttcagagcct ttagcttgat aggctttacc gtcaagaaca atcaactcac
     6001 catcgataga atctaatgtt ccgaggccca agtctccatg ctctaacaac tctccaacag
     6061 ttaaagtacc tccataaagc ccagccatca aggctcccaa agtattatat tgaaataatt
     6121 ttatggcttc agacatgtct acaccctctt tttagtaaaa ttcatctggc aaaatagttt
     6181 cgccgagttt aatgttatct ctatagtcaa ttggaacatc aataaggact ggtccatcta
     6241 cagcctgagt caaagcctct tgaagcaagc tagcaaacgc tgctttactt gttgcacgat
     6301 aacctttggc tccaaagctc tcagcatatt ttacaaaatc tacaggacca aagtcaaccc
     6361 cagatgaacg accgtacttc atttcttcct ggaattccac catattgtaa tgaccatcgt
     6421 tccagataat atggacaatt ggcaatttca aacgaactgc tgtttccaat tcttgtgctg
     6481 agaagaggaa accaccatca ccagaaacag aaatcacttt tgtcttagga cgaaccaaag
     6541 ctgcagagat agcccatgga agagcaacac ctagcgtttg catcccattt gagaaaagca
     6601 aatgacgtgg ttcatacgat ttgaaataac gtgccatcca aatatagtga ctaccaacat
     6661 caaccgtaac agtcatatca tcatctgttt gttcttgcaa aacttcgatt aaatctagcg
     6721 gatgcaccgt accttcatca ggctgacggt caaacttaac atcctcaaca acattgtttt
     6781 tcaaaccttt aagatattca accgaacctt caggcaattt ataaccttga atagcgggca
     6841 aaagcaagtt taagctcgct tctacattac caatcaattc acgttccggt tggaagtaag
     6901 tgtccacctc ggccggctca acatcaataa cgatgatacg tgctgaaatt tcagcattcc
     6961 agttacgtgc ttcatattcg attgggtcat aaccaatggc aataactaag tcggattttt
     7021 taagcaacat gtctccgggt tggttacgga aaagacctac acgaccaaag aaagtatctt
     7081 cttcaaggtc acgtgacacg ataccggcac cttggaaagt ttcaacaact ggcaatttaa
     7141 catgcttcaa aatttggcga atagagtaag ttacggcttc tgatgaggca ccattcccca
     7201 aaagaaagac tggcaacact gcatttttaa tggcttgtgc tagatagtta atatcagaaa
     7261 cagatgctga accaagtttt ggatctgtca taggcttaat agccttaaca ctgaccggag
     7321 catccgtcac gtcttgagga attgaaatga agcttgcacc tggtttccct gacttagcgt
     7381 gacgataggc attagcaacc gtttcagaaa gggtgttagc atcatgtact tcagcagcat
     7441 atttggtaat tggctcaagc atagcaacgt tattcattga ttggtgggca cgtttcaaga
     7501 gatctgcacg cttaacctga ccaccaatag caagaacagg gtctccttca tccgtcgctg
     7561 ttaccaaacc agtagccaaa ttggagacac ctggaccaga tgttaccaat actacacctg
     7621 gtttcccagt aatacgtcca acaccttgag ccataaaagc agcattttgc tcatgacggg
     7681 caacaatcaa ttcaggtccc ttatcttcca aggtatcaaa aaccctatcg atttttgcgc
     7741 ctggaatccc aaagacatac tcaacatcat ggttgatcaa actatcaacc actaaatctg
     7801 caccatacaa ttgcttttct tctgacatga acacagtcct tctagcccta aaatggtaga
     7861 gccaactttc ctttcaagta taagtcacaa agtgtcaaag tctgctcgtt ttttcacaaa
     7921 ctttcatcaa ttcacaattc tgttatcatt atagcacagt tttcagacaa tcttgtgaaa
     7981 aaaggcagac taggtgacta aaaaaagaca aacactcaaa atagcgtttg tctactttat
     8041 aaattaacta tctcatttgc ttgttttctg atttataaat attacttatc aatgcttagt
     8101 tttttgaggt ttacaaacac acaataacac agaagaataa acagagcaaa aacagcaaga
     8161 cttctgaaaa ctaaaacaag atgactactt aaaaaggcaa aacttcctat tactaaaaca
     8221 gcaatgcctg aaaatacaga atgtaaggtc tccgagtaaa tatatagttt ctgtaattct
     8281 ttcatgttaa gtgacaactg aaaataattg gtttcgatta tccccatcat tgtctgacct
     8341 atcgctagaa aaacataact cattagtact gtataaatgt tcgaagatgt actaaataaa
     8401 agtagatata gaacataaaa tgaaagacct aaggcgaaag ctttcatatg agaacttatt
     8461 tgtttcacga agctaagaag gaagctcatt actaagaatg aaactgctaa aaatgataag
     8521 gaaaaggaat acatagaatc actaataccg agatactttg ttaaataaac aacttcataa
     8581 gtatcataaa caactccaat tgatcccaca ataactccag ataatagaac taatgcaatt
     8641 tttttggatc tcagaatgtt aaataatgta atgtttaaat tttgtttttt tctttcttct
     8701 ttcaaattta aagtcgaaat atttggtaaa aataaaagac tagtagctcc cactatcaaa
     8761 agaagagcat aaactgcaaa caataaaaag tgacttttat taataaataa accaacaaac
     8821 aacggtgcta aaaaataaga tactgaacca atgcttgtat acctagcgtt aaacttaatc
     8881 aatgaatcct tgtctataat aattggtaca caactatata ataaactgga aaacaataca
     8941 ttgacaacct caattatgaa tacaactaat aggacaatta tatggtttaa tccaaaacct
     9001 agtaagaaaa gtaagattgc ctttgtaatt tctaacagaa taagcaggta ttttctgctc
     9061 agtttactat ttgagatatt aatcctattt gtaactattg cagctaaaca ctttaccacc
     9121 caaaaataca taactaattg cacagaaatt ctagacaata gaatgttgat caagatagta
     9181 taaccatact ctgagattaa cgatgagaaa cgattaaaat aaatactcaa tgctgcatat
     9241 ttttttattt tcaatatttc ctatatcctc cttaattttg atttaacaaa ttgaatcatt
     9301 tggtaaaaaa tgtgagcatt atcacttcca accatcggat tgtactcaac tatatcacaa
     9361 aaatatacct tatcagaaca taaaattttg gaaattattc caagaaaatc gttcatttga
     9421 aatcctccaa taataggata tgatactgaa tcaaaaacag atggatccaa aacatcaatg
     9481 tctattgata agtaaatatc ttttgactca tcaatataac tatctaactt tttcaaaact
     9541 ctactcttat ttaaccaata ctcctccatt gagaggatga ttattttatt atcaaatgaa
     9601 ctaggaaact caaaattcct ttccccaatg ataattattt tttcaaaaat atcggttaaa
     9661 aaacttaaaa aattccaatt ttttacaaca ctttcaaagt ctttgaagta atctaaatga
     9721 gcatctaaaa caattaaata tgcttcctct cgaacagtgg cctttgctaa tagataagta
     9781 actgaatgat ctcctcctaa agcaatctga actttagatt cagcaatagt tcgacttaga
     9841 ctttctaaat caatagaaaa taaatcttga ttacctaaat taattgtaat tatatcagaa
     9901 tctttcctat catataacat cgcttcttga taatattttg tgggagcaaa tctcgctcct
     9961 ggaattctac ttccaccatc ataaataata gataatattt tcataaactc attgactttg
    10021 gcttaatccc agttaaatta tatgctaact tgcactcctg tatatcggga ctcccaatag
    10081 aacctccgaa aaactgagct cgacttctac acccaccttg acaaacataa tttgcagggc
    10141 attcattata atacttacat cgtacatttc gaatatgatt gaagaacttc gaattaatcc
    10201 aaatatcatt taaagtcttt tcattaatgt tacctccaca aaatttagtg gaggataatg
    10261 tcggacaaaa tccaacatca cctgacgaat ttataaacac ataagaattg ccagcaccac
    10321 aataaaatga ttcaaatgtg gattcggata tattattaca atttgcttga atattgggaa
    10381 tacacaaaat agcattattg aattcttcat cactaattga tagtcgatta ttcctttcaa
    10441 aaggtaaaaa cctatcaaaa gcatatttca catctaatcg atcaaacaac tccaaaaaat
    10501 acttcactcc actaatattc ttgttattca aaacaacatt aacagtaaca ggtactccta
    10561 aactcctaaa atattcaata ttcttaattg ttctcttaaa tgtacctctt cctctaattg
    10621 aatcatgtat tgtttcattc caaccatcta aactaacttt tagtcttata ccatcatatc
    10681 tttgaatcaa tattttaaaa tcttcaggaa tatatacagc atttgtaaaa attgttgtac
    10741 acattccctc ttttaatact tcctcgataa tttcacttaa tccctgtaat aataatggtt
    10801 cgcctccagt gaaatcaaca tccattactc ctagctgctt agcttcatat actatacttg
    10861 aaattttctt tctatcgagc tcctttgaat aatcaggtaa ataacaatgc atacatctta
    10921 ggttacattt gttcgtgacc tcaatctgta tcacttttaa tggtattttc gttgaaaatt
    10981 caacaatttt agtgttggtc ttagagagtg atatttcatt gttatttaga aaatctataa
    11041 cattttttat tacctgactc tttgaatcag aaaacttttt caatgaaaat tggtacataa
    11101 attttaaagc taaaaatgta gctaaattta atgaaaatag tttattattc ctattattcc
    11161 tgagtattcc ttgcttattg taccaattaa aaaaaatcga gtaaacattg ctcgtcatat
    11221 taattccctg caatcttcca aaaatattaa tataaaaacc aaaggattag aaatagactc
    11281 taatcctaca atcagttcta ttagacagac ggtgggcaac gacctttgag tccatcaatc
    11341 aactctgtag caacagaagg tttaatttcc ataatgtcaa tagatagacc gctagaaaca
    11401 acttcttctt cttctgctaa ttcaatttgt gcaatagcat cactaacttg catcgtaata
    11461 tcctccatta tttatttaag aatcaataag tacccataac aaatcataga aatcattctt
    11521 tatctataaa atttagctga aaatgctttg aaattgtctt attaaactga tttgcaataa
    11581 taaagtatat gttatctgtt cgtatatatg atattttttt ataaacatct tcacaaactc
    11641 tcttgtaaag attccaaaat tgatttgctt gtgaacttgt ataagataag ggtatacttc
    11701 cccatctaaa atctaaataa tatatatacc atttttcata ttctttaaac tctgtagtgc
    11761 catcggcagt ctttgttcga taatactctg ataaagtgtt tttaaaattg ttttgatact
    11821 caatctcata tttcagcctt tcctctgaaa catgcaaaga cggactaaaa actggcaccc
    11881 cagttttaat atatcgtaaa actacatcct ctatatcctt gtacctctgc ccctcaccaa
    11941 ggttcagttg aaatgtcgga caaggagtaa aagaaacaat atagaagttc tgaattttct
    12001 taatatgaaa aggatataat tcacaagtta atggcttgtt caagcctaaa tcatttatcg
    12061 tacaacccaa ttcagaatga aaccagcact ttttaccaca actcaacaat gaaacactat
    12121 catcactaac aataaaatct ttaagatacg tgcgttttag aaaacttgct gtctttgcat
    12181 caagtaataa agaattattc acatgacaac aagatcctct acacttttca caattataag
    12241 agataatatc atctagaaac gtataatgaa tgatatcttc tgaaatctgt tcaggaaatt
    12301 taataattct catatcaata atatatcatt taattttgac actgataatt tataccatat
    12361 acacaaatcc aactacattt ttaacactcc agataaatga ttttcaaatt ttatagctaa
    12421 attctcacta ttagccagct taattgcagc aatacacttc ttcatttcta gaatagcttt
    12481 attgctccta ttcttcttta attcatataa attttttgaa taatgaaaca ctaatttctc
    12541 gtaaatctca gtttccgtaa aacaactatg atttaactgt ttttcaaaat acaacgaatc
    12601 aatatactca tctctttcaa tacttatgat ataacaattt aatagcattg ttgagtgtaa
    12661 ccttcggtag tttggtaaat ccttgtaaaa ttctgaacgt ttacacattt ctcttgataa
    12721 aagcatcatt gtttgatgat tcaatacatc tacagtattc gcaaataaca gtagttcgta
    12781 acaaccccaa tattctacag agaataggta gtctgataaa tattggatat cagattcatc
    12841 atagtaactt ttgtctgata agtcctgtaa acgaattttt attaaaatag tatttagagt
    12901 ataaaaagtc tcacgctttt cgattttttc tacttgagag attaataact tttccatacc
    12961 tgacacgttc cttgctgaaa caaataaact aatcttttct aagatttcat taaactcatc
    13021 tctctgaaag tcgtttgctg catacataaa ctcatcaata ggcatattta tcgcatttaa
    13081 agctgacata aacttactaa ttgtcaaatc tgtattttca cgttcaaagc gggaaatatg
    13141 agatactgat acgcctaact ttgcgatatc ttttaagact aatcccctag actctctaaa
    13201 tttcttaaat aattttccat aatctttcat aaaaagcacc tcttttgcat atacgagaat
    13261 ttcccagata aacttaaaag tattatatca tatagtgaga taggaggtta atttctatga
    13321 ataaagaaag ttttttagct atcttacttc taatttttga aagcattatt gtaattgctg
    13381 ttggctaaac aaatagaaaa taaagacacc acaaaagtta gactttcgat gtctaacttt
    13441 tgtggtgtag ttaaggtatg atgctgttct ctaataaggg tataatataa aaaagactct
    13501 atgatttctg tagtaggtaa aaccactata gagattatag agctttttga gtgtatacaa
    13561 aaactagttc tttattggaa caaagtcaac aactaatcta gtattggttg cagcggcaat
    13621 ttcttccaat gttttatatg ttggattagt ggtgccattc tctatacgtc actttgagaa
    13681 ggtaaatttt aaaatcctct ttatcataac tttttactaa aatagccaga acatcacatt
    13741 ctactatcat tcttatttct catcttcgtc cattgaaagc acagacaaga aggcttcttg
    13801 tggtacctcc accgaaccga tggctttcat acgtttctta ccggcttttt gtttttcgag
    13861 gagtttacgt ttacgtgaaa cgtcaccacc gtaacattta gccaagacgt ttttacgaag
    13921 agctttgata tctgtacggg caacaatttt ttgaccaata gccgcttgga taggaacttc
    13981 aaattgttga cgtggaataa ttttcttaag tttatcaacg ataagttttc cacgttcgta
    14041 ggcaaattct ctatggacaa taaagctaag ggcatcgacc ttatcaccat taaggagaat
    14101 atccattttc accaattgtg aacgacggta ctctgacaat tcatagtcaa aacttgcata
    14161 accacgagtt gatgacttca atttatcaaa gaagtcaaag acgatttcag caagtggaat
    14221 ttgatagata acgttaacac gattatcatc aatatattcc atggtttcaa aatcaccacg
    14281 tttacgttgc gccaactcca taacagcacc aacatactct tgaggaacca taatttgagc
    14341 tttgatataa ggctcttcaa tggtatcaat acgtgtagga tctggaaatt cagatgggtt
    14401 ggacacttca agcatttcac cgtcagtagt gttaacatgg taaactactg atggtgcagt
    14461 catgatgaga tcgatgttaa actcacgttc caaacgctct tggataacat ccatgtgaag
    14521 aaggcccaag aaaccacaac ggaaaccaaa accaagggct tgagacgttt caggctcaaa
    14581 ttgaagactg gcatcattca attggagctt ttcaagagcc tcacgcaagt cgttatattt
    14641 atttgactca atcggataaa gaccagcaaa gaccattggg ttcatttgct tataaccatg
    14701 aagtggttct gcggctggat tatccgcaag tgtcactgta tcaccgacac gagtatccgc
    14761 aactgtctta attgaagctg ctacataacc aacatctcca gtcgcaaggt agtcacggcc
    14821 aacagcttta ggagtgaaaa taccaacctc agtaacgtca aaggtcttgc cattagacat
    14881 catttgaatc ttatcgcccg ttttaaccat tccgttaacc acacgcactt ggagtatgac
    14941 gccacgatac gcatcataaa cagagtcaaa gataagggct tggagaggtg cttccacatc
    15001 accttggggc gcaggaactt tctcaacaat ttgttcgaga atctcttcga taccaatgcc
    15061 agccttagct gatgcaagca cagcttccga ggcatctaat ccgataacat cttcaatctc
    15121 tgtacgtaca cgctcaggat ctgccgctgg aaggtcgatt ttattgataa ctggtaagat
    15181 ttccaagtca ttatcaagtg ccaagtaaac attggcaagt gtttgtgctt caatcccttg
    15241 agctgcatct accaccaaga tagcaccctc acaggcggca agggaacgtg acacctcata
    15301 agtaaagtcc acatgtcccg gtgtgtcgat aaggtggaaa atataagtct cgccgtcttt
    15361 agctttgtag ttaagctcaa tggcattcag tttgatagtg ataccacgtt cgcgctcaag
    15421 atccatacta tcaaggagtt gtgcctgcat ctcacgactt gatacagtct cagtcttttc
    15481 caagatacgg tcagcaagcg ttgatttacc atggtcaata tgagcaataa tcgagaagtt
    15541 gcgaatcttc tcctgtcttt gttttaattc ttcaatattt ggcattttat tctttcctag
    15601 ttcttacttg tgattgttaa aaaacgaacc gtcacctcct attatacaaa aaagacaggc
    15661 atttgcctat ctctaatatc tgctttatga ctgcatttag tccttcttat ttcttaaaat
    15721 tatcattgta gtgcttatta ataatagctg aacgcttgtt ctctattgaa ctacttgaaa
    15781 atggagctaa accaaaggct agtacaataa ttcccaatag aataagacta aaaaatgggt
    15841 gctcagcaat atagtgtaag atgtctgata tgggaatcca cctttaaaaa cataattatt
    15901 tataactata ttatcagaaa cattatgttt tatcaagcaa aaaaagagag ccattcgctc
    15961 tcccttttaa ccttaatgga attgcatacc accatcaacg atgattgttt gacctgtgat
    16021 gtagtttgag tcaggtccag ctaggaagct aactgctgct gcaacatctt caggttctga
    16081 caaacgtttg agggtaatat ctttagcaaa agtttgcata ccctactcat catctttacc
    16141 agcattttac caacttcgtg ggaaatgtca aacatcattg gagtcttaac gatacctggt
    16201 gcataagcat ttacagttat acctgaatca gctaagtcac gcgccaaagt ttgagtaata
    16261 ccacgaacta cgaatttagt tccaccatat acagttaagt tagagttccc tacaacacct
    16321 gcttgtaaag ttgcattgat aattttacca ccatgaccaa gtgatttaaa ttgtgcttgg
    16381 gcagcttgtg cacctcagat aactccacca acattaatgt taaatgtacg ttgaaactgt
    16441 tcttcagtaa tagtgtcaag ggggttttgt tggtgcacac cagcattatt aacaacaaca
    16501 ttcaagtcgc caaagtgatc aactactttt tggaaagctg ctgctacctc agcttgttta
    16561 gacacatctg ctacaacgga aaatgccttg tcttctgaca actcaacaac tgctttttca
    16621 gcagtttcag cgtcatagtc caataccccg actttaaaac catcttcaac caagcgtttt
    16681 gaaatcgcaa aaccaatacc ttgacctgca cctgtaacaa tagcaacttt tgacatacga
    16741 aatcctcctc taccaattgt agtcacaagc ttaaccacaa gccctatctc aattggaata
    16801 tgctaagtta atcaagttct ggcaaagtca ttttcatagg ctttgtctta actcaattaa
    16861 gattctaccc ctttataaaa gcgttgttaa taatttgtca tgctttttga aagcaaataa
    16921 gatcaccact agtgacctta tgtgtattat ttttcaaact taaaccctag tgcttccata
    16981 tcacctaggc cacctaaggt ggtaacctta gtatatcctc gttctttcag tacacctgca
    17041 gcaaattcag cacgagatcc cattttacaa taaagataaa ttgaatcgtc ttttttagct
    17101 ggaatgtcag ctgtgaaaaa ctgcgtgtga ggtattaata aagcatcctt aacatgacct
    17161 tctgcgtact cttctggagt cctgacatca attaatagtc catcctgagc taattctgat
    17221 tgaatctgtg ctatatccat cctactcacc aaaccaaatc ttaatttctc gagccgcaga
    17281 ttcttctgaa tcagagccat gaacgatatt tggaatcatg tcaccatctg gtgctgttgc
    17341 aaagtctcca cgaatcgttc caggagcagc atccccagga ttagttgctc ccatcatatc
    17401 acgccatgac ttaataacac ctgggccgga cataatacca ataactgctg gaccactcat
    17461 catgaattca gaaatactag ggaaaaaagg tttatcagcc aattgggcat aatgttcttt
    17521 aagacgttct tcgtcaagca tcagcatctc catacgctca ataacgaagc cacgtcgctc
    17581 aattcgatca agcacttgac caattagatg gcgtttaaca gcatctggtt taataataaa
    17641 gaatgttttt tgcatattcc caaccttcat cgttttcttt ccattttatc ataagaagta
    17701 tcattttgca gagctaaacc ttgtatagtc taaaactata tccacagcaa gaaattaact
    17761 atttttcatt agttcccata agagataata tagatgtaaa tagacatttc gaggtaaatt
    17821 taatgacaaa atctaaattc caattagtcg gttctcttct tcgtcctgcg gatctccgta
    17881 aatacaagga cgaaatcgag catcgtgacg acatccagta tcctttctat gatgcccttc
    17941 ctggttatca agaaactgaa actgcatcta ttaagtgaat gtggctgacc aaaaagctaa
    18001 cggaattgac atccttaccg atggggagtt tggacgttct atgtggcact tggactttgt
    18061 ctggggactc aaaggtattg aacgctacat tgctgagcat ggttatactt ttaaagacca
    18121 tgatggtggt caatatgaaa cacgtaaaga tatcggtatt cgtgtcactg agcctctctc
    18181 aggtaaaaac caccactacc tagatattta caaattggtt aaggctgaag ctggtgatga
    18241 agataccaaa caaactatct ggggacctgc tcatacctac actgaacttg ctatctttga
    18301 tcaattggct gttcctggac aagtctatga aacaaacgaa gaactcaaaa aaggtttgat
    18361 taatgtctat aaagaattct tagatgaata caaggctgtt ggtggtaaaa tcgttcaatt
    18421 tgatgactgc ctctgggaac tttttgaccc atcaaaccct gcaagtttct actcagacgg
    18481 caatggtgat ttggcagaat tggccgatga atttgttgct atcaataatg aggttgttga
    18541 ctatactcac gaacttggtt taacggtttg gacacacaac tgtcgtggta attatgaaat
    18601 ccgttctgct gctgaaggaa cttacgaaga catcgctaag aaattcttgg cagagcaaca
    18661 ctatgaccgc ttcttccttg aatgggatag cgatacagct ggtgatatca aagctctgga
    18721 agcccttaaa gacagtaaag ctgaagttgt atttgggcta ttgtcttctt aaacgactga
    18781 cctagatgac gaagaacgtg ttctcgattt gcttgaaaaa gcgagtcaaa tccttccaaa
    18841 aaaacgtctc ttcctctctc accaatgtgg tttcgcctca tgtgactcag gtaatgagct
    18901 ggcaacacct caacaatggg ctaaaatcaa acaaggtcaa gaaatcgcta agaaattctt
    18961 tggctaatcg atatttctat tcgctcctct ctaaaacgaa aagccttcac tcttgtgagg
    19021 gctttttatg ttagcatcaa gcatctataa aagtttgcaa atccttaaga gatctttctg
    19081 cgattttttc ataacgctct ttcttgtcac gaatacgtgg gccttctaat tctttgataa
    19141 taccaaagtt aacattcatt ggttggaaat gtttgctttc agcatgtgtc acataatatg
    19201 gaaggctacc gattgctgtt gtatgaggga aaataacttc atcttcaccc ttaaaaagac
    19261 gggctgcatt gattccagca accaaacctg aggcagctga ttcaacataa ccttcaacac
    19321 cagtcatttg tccagcaaag aacagattag ggtttgattt tgattggaag gtctgtttaa
    19381 gcaagtttgg cgaatccatg taagagttac ggtgcattac cccataacga acaaattctg
    19441 cattttcaag acctggaatc atttggaaga cacgtttttg ctctccccat ttgaggtggg
    19501 tttggaaacc aacgatattg tagaggctac cagccgcatt gtcctgacga agctgaacaa
    19561 ccgcataagg ggtcttgaag tcaccatcac gtggacccat ataatcttca ggatactcca
    19621 aaccaactgg tttcatagga ccgtagagca ttgttttaat accacgttta gccataacct
    19681 cgataggcat acacccttcg aaatactttt ctttttcaaa agaattcaaa ggagcttctt
    19741 cagctgtagt caaggcctca tagaaggcca tgaactcttc cttggtcatt ggacagttta
    19801 gataagctgc ttcaccctta tcatagcgtg acttaaggta aaccttgttc atgtcgatag
    19861 ttgctttatc aacgattggt gcagcggcat catagaaata gaacccgtct ccaccgttaa
    19921 gctcatgaat cttttcagct aaagcatcag aagttagggg acctgaagca ataactgtaa
    19981 tagcatcatc aggaatttct gtgatttctt tacggataac ttcaattaag ggatgacttt
    20041 caatttcagc tgtcactgct tctgcatagc cttcacggtc caccgccatg gcaccacctg
    20101 ctggcacacg gtgagcttct ccattacgca taatgataga gtccaaacga cgcatttctt
    20161 cttttagaag ccctacagca ttggtcaagc tatctccacg gaaagagtta gagcaaacca
    20221 attctgcaaa atttgttgtc ttatgctgtg gtgttgcttt gaccccacgc atttcataaa
    20281 gttttactgg aataccacgt ttggcaatct gataagccgc ctcggatccg gccaaaccag
    20341 ctccaatcac gttaatataa tctgcttttg attgagacat gacactaata cctcttcgga
    20401 aacaagatga aatcctgctc ccacaaatct ttcttcattt ttactcttag tagtatagca
    20461 aaaaactcct catctggcga ctaggagtca tctgtattta aaaggggtaa aatgatagtc
    20521 actttagcac cacccgtgcc attgtcattt gcaagagaaa gactaccata gtgtaaacga
    20581 ataatatcat tggcaatagt cagaccaagg ccactatgat tgcgactatg tctgctttta
    20641 tcctcttgat aaaatagctg agtagcgttt tcaagagatt caagggaaaa tccaggacca
    20701 gaatcaaggc atataaactt gaattcatct tcttctaccc tagcggtcag gagcaactga
    20761 ctgccactgg gtgtatgctc tacggcattt gaaacaatat tcataatagc tcgattcaac
    20821 aaggacttat cccaattgcc tatgctttct ttcgcaattt ccttcttgtc aaataccaca
    20881 ttgatttgtt tcgtttgagc taatgacaag gtttgatcgt aaatgtcttc aacaaattcc
    20941 ttagctggaa cttcttcaag cgtcagggtc ttcttcaaac tcattttgtt gatttctgac
    21001 aactctttta cataagtatc aacctgtgca ataccttttt gaaaatgctc taacaagtcc
    21061 gtttgatttt catccaagga cgtcatagct aagagttccg catttccacg agcaactgtt
    21121 aggggcgtct ttaagtcatg tgtcagggca gaaatctgat tttgtttatc ttgctctgcc
    21181 ttccaatttt ccatcaaaga ctcacgaagt gctatacgca tatgatccaa accacttaaa
    21241 acctgattaa attccttaat tgtagactga gaagtttgaa aatccaaatc ttgttgggaa
    21301 attttttcag taacccttaa tataggttta agttgctgac tcaatttatt tgcataataa
    21361 aaagttaaaa taataaatat gattaagata gatacaaaca ttgaaccaat catcataaga
    21421 tcagcattgg gaaaatgctg gttcatccac tcattacggt accgaggtga tagttgataa
    21481 ttgacaatga ctatgccatc tgatcgttca aaagactgaa aatagccgta tttctcaccg
    21541 tgagcattct tgaattggta atttagtaag gattcttctt gcaagttaac aggcatgtta
    21601 gactttttaa gcttaaaatc tctagttaaa aagacataac tcgtgccatc aggtaaaatc
    21661 tcgggattaa agaccttaga agtttcaata tcacttctca cagcagacaa atcactctca
    21721 acttgatttg ctggaatcaa aactccaaaa cgaaaagaca agctgaacaa atacaaaata
    21781 agaagactgc tgattacaga gagaactgta agactgacga cataagataa caagattgtt
    21841 cttagagagt gttctcgttt ttttattagt gccacttgta accaatcccc caaactgttt
    21901 caataggatt ttgcccaact tctttaagct ttgcacggat attcttgata tgttcagcca
    21961 ctgctgccgg actgccttta tcctcatagc cgtacaaatg cgtgtagatt tgttcttttg
    22021 aaaagacttg gcccttattt tcagctaaaa actggcaaat accatattcc gactttgtca
    22081 aatctaacaa ctgattctca atataaagct cttgagcaga caagtcaaac tgaaactccc
    22141 caagtgaaag cttatggtga cgctcacgat gttcacgtct caagtgagct gcaacacgcg
    22201 cttggagttc tttaactcca aatggtttgc aaatgtaatc atccgcacca taactcaacc
    22261 cttggacaat gtctgcttct tgcgttttag ctgtaataaa gaggattggg caatccacct
    22321 gatttcgaat ctcatggcaa aactgtagac cttcaacatc aggcatcata atatccagta
    22381 aaatcaggtc aaatcgaggt aaagagttct tatccaaatc taaaacactt gtaagccctg
    22441 tcacattatg gttttggagc tctaaagcct ttacaaccaa ttgaacaata tctttttgat
    22501 catcaataac aagtattcga gccatagcct ttcctttcct tcaaagttat ccatatcata
    22561 tcatctatag aagataactg acaaggcgta aagtagataa atatgggttg ggtaaaaaac
    22621 atagaacaaa tattttgacc ctttccctct ttgaccgtta taagaaagca ttaaaggtgc
    22681 tgaaaatatt tccatccatt caaagtattt gaatattaaa tcgtgaaaag aaggtctact
    22741 taaaacaatc gccattagca gccaaacgag actaacactc ataaaagcaa gcacttcttt
    22801 cttaagattc ctatgacaaa gatacatagc gataccggtc aaaagcaacc acgttcctcc
    22861 atcactgata aatgtatgga ctggcaatac tgtgaaattg agtaaattta gtagaaaacc
    22921 aaacataggt ttgttcacac ttagcagata aaaaggcatc attaaccatg gaagcaacaa
    22981 tggaaaaagt aaagttggta tccctttaag gtatttcttt tcttgaatcc atgcaatccc
    23041 ttgaagagca acgagcaaaa ttgcgaatga cgacagcatc atattttgtg gaaagaaacc
    23101 atctggtcta actagaggat gtagaaaatt atagaatcca aattgaatca gtcccatcac
    23161 aattgctaaa gaataaatct ttaggaagta tttcttccgg ttatgggtat gaataaaacc
    23221 ctcaatcaca
//
