LOCUS       gnlProkkaBPLBJJKO_1    23227 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BPLBJJKO_1.
ACCESSION   gnlProkkaBPLBJJKO_1
VERSION     gnlProkkaBPLBJJKO_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 20:55:55
            Original ID  :: gnl|Prokka|BPLBJJKO_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 865429
            Orig. end    :: 888656
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23227
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13227]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23227
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23227
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="4"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             983..2326
                     /locus_tag="ctg1_878"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(2591..3382)
                     /locus_tag="ctg1_879"
                     /transl_table=11
                     /translation="MADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPTSF
                     YSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSASEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             3693..4121
                     /locus_tag="ctg1_880"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             4123..4416
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.2;
                     E-value: 2.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_881"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             4627..4968
                     /NRPS_PKS="Domain: PKS_KR (3-111). E-value: 1.4e-10. Score:
                     33.2. Matches aSDomain: nrpspksdomains_ctg1_882_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     109.7; E-value: 2.8e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_882"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVSPTKSLDTITEEQFQRT
                     FNINIGGVI"
     aSDomain        4636..4959
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_882_PKS_KR.1"
                     /evalue="1.40E-10"
                     /label="ctg1_882_PKS_KR.1"
                     /locus_tag="ctg1_882"
                     /protein_end="111"
                     /protein_start="3"
                     /score="33.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVSPTKSLDTITEEQFQRTFNI
                     NIGG"
     CDS_motif       4642..4710
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_882_0001"
                     /evalue="1.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_882"
                     /protein_end="28"
                     /protein_start="5"
                     /score="11.6"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAISKRLVEDGVK"
     CDS             5244..5390
                     /locus_tag="ctg1_883"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             5778..7610
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.4; E-value:
                     9.1e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_884"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDAIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             8016..8357
                     /locus_tag="ctg1_885"
                     /transl_table=11
                     /translation="MDITNFIPSQRQAMLERFQQVEALGLGAVRIELKVANPVGIIYEC
                     YIMSGENYFSDQAVVSFRILYEKDLDRISLDVVDIPGRSSLSNYLQLLEIFEGLQHYLN
                     REFAKVKNT"
     CDS             8796..9080
                     /locus_tag="ctg1_886"
                     /transl_table=11
                     /translation="MDNTKDLSNPETASNKAPSKLTFIYYDEDEFAAFLDSLPLTVASK
                     VIARIREVSAIGIAEAMALKLVRKVDRKKDIFELRINTEGIFARSLFSV"
     CDS             9338..9667
                     /locus_tag="ctg1_887"
                     /transl_table=11
                     /translation="MKEIKLTPLDKVDRNGFLASYLAERSKKEPEILQHYNNEIECIKL
                     SHKIKQLRENINLTQQELADRMGKSQASIGRIENGTTNPTYKTLEEIAAATNTRLVVDF
                     VPIKN"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_888"
                     /sec_met_domain="TIGR01716 (E-value: 7.5e-44, bitscore:
                     146.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVECWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDSLYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKYIAAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             10918..11718
                     /locus_tag="ctg1_889"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             11778..11927
                     /locus_tag="ctg1_890"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             12010..13227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_891"
                     /sec_met_domain="Streptide_RRE (E-value: 5.9e-15, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-20, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.3e-09, bitscore: 32.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.7e-10, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.3e-08, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             13224..13967
                     /locus_tag="ctg1_892"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             13974..15146
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_893"
                     /transl_table=11
                     /translation="MKIKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             15400..17076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 504;
                     E-value: 9.2e-153)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_894"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.4e-50, bitscore:
                     168.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.2e-45, bitscore:
                     149.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALAQAVDGPVLIDVPIDYKDNIKLGETILPDEFY"
     CDS             17092..17811
                     /locus_tag="ctg1_895"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(17932..19188)
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 406.3; E-value: 2.2e-123)"
                     /gene_kind="other"
                     /locus_tag="ctg1_896"
                     /transl_table=11
                     /translation="MRPIKNTTELIGIKDQNIKISLVFETDTHIEIQAKLDYPAPSCPH
                     CHGKMIKYDFQKPSKIPLLEQAGTPTLLRLKKRRFQCKSCRRVTVAETSIVEKNCQISN
                     LVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKKHYDKLPAVMSWDEFGFKK
                     GELAFVAQKYETNELITILDNRCQTTIRNYFLKYPLKARQQVQFITMDMSGAYIPLSRR
                     LFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRLFQKDSCKLSL
                     NSFYSKTFRQTLAPHEVVKKTLVFSKELTDYYTLYQLLLFHFQEKRVGEFFDLIEENRS
                     KVNHYFQTVFRTFLRHKQYIQNALETDYSNAKLEATNKLIKDIKRLGFGFRNFINFKKR
                     VFITLNIHKKRTYPVLSRC"
     CDS             complement(19445..20149)
                     /locus_tag="ctg1_897"
                     /transl_table=11
                     /translation="MTEKGIIISEKLADLAGISVGDEVTVQNSQDKDIKLKVAGISEMY
                     MGYFIFMNESTYKDAFGKEASQNATILTLKDHSDKNVEQTASRFMSLDGVKGDVQNTTL
                     KAQIKTIVNSLSRVMGVLISVSILLAFVVLFNLTNINVAERIRELSTIKVLGFFNKEVT
                     LYIYRETICLSIIGILVEFGLGLGLHQYMVDVIPPENIMFNPNLGWLIYAVPTLVIIII
                     LTGSGYLCEPTP"
     CDS             20401..21123
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     76.3; E-value: 4.3e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_898"
                     /transl_table=11
                     /translation="MRGRVSSYLADFSKLDNVYRFVEEIKRDFQRIDILFNNAGLYAGK
                     ERKASGENVELTFMLSVLVPYIFITELIPLLEKLPDGLVINTSSYMHHFAKVKDLDFGF
                     EKEYNPGLAYNNSKLYTIWMTRYLARDFFLKGSNTTINAYHLGLILTNLGNNSSDKKTE
                     KSLFGRLMKSLSKDLDQGIETGYYLTLSEEVSGLTGYYFDEKKVKSVSEKVYSFEKTQK
                     LMNYCQEKVKMFKEKQNV"
     CDS             complement(21556..22131)
                     /locus_tag="ctg1_899"
                     /transl_table=11
                     /translation="MYVTEQFVYSVHMTAQDRRITKTRKAIYQAFLYLLNQKDYEAITV
                     QEIIDLADVGRSTFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKN
                     QDHVTSLLLSKNDYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVVTNFIETL
                     TWWLKKGKSYSEQEVVQFYLEILNVASN"
     CDS             22229..23125
                     /locus_tag="ctg1_900"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFAIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENVSKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAVVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDVVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
ORIGIN
        1 ttttattatg caaataaatt gagtcagcaa cttaaaccta tattaagggt tactgaaaaa
       61 atttcccaac aagatttgga ttttcaaact tctcagtcta caattaagga atttaatcag
      121 gttttaagtg gtttggatca tatgcgtata gcacttcgtg agtctttgat ggaaaattgg
      181 aaggcagagc aagataaaca aaatcagatt tctgccctaa cacatgactt aaagacgccc
      241 ctaacagttg ctcgtggaaa tgcggaactc ttagctatga cgtccttgga tgaaaatcaa
      301 acggacttgt tagagcattt tcaaaaaggt attgcacagg ttgatgctta tgtaaaagag
      361 ttgtcagaac tcaacaaaat gagtttgaag aagaccctga cgcttgaaga agttccagtt
      421 aaggaatttg ttgaagacat ttacgatcaa accttgtcat tagctcaaac gaaacaaatc
      481 aatgtggtat ttgacaagaa ggaaattgcg aaagaaagca taggcaattg ggataagtcc
      541 ttgttgaatc gagctattat gaatattgtt tcaaatgccg tagagcatac acccagtggc
      601 agtcagttgc tcctgaccgc tagggtagaa gaagatgaat tcaagtttat atgccttgat
      661 tctggtcctg gattttccct tgaatctctt gaaaacgcta ctcagctatt ttatcaagag
      721 gataaaagca gacagagtcg caatcatagt ggccttggtc tgactattgc taatgatatt
      781 attcgtttac actatggtag tctttctctt gcaaatgaca atggcacggg tggtgctaaa
      841 gtgactatca ttttacccct tttaaataca gatgactcct agtcgccaga tgaggagttt
      901 tttgctatac tactaagagt aaaaatgaag aaagatttgt gggagcagga tttcatcttg
      961 tttccgaaga ggtattagtg tcatgtctca atcaaaagca gattatatta acgtgattgg
     1021 agctggtttg gccggatccg aggcggctta tcagattgcc aaacgtggta ttccagtaaa
     1081 actttatgaa atgcgtgggg tcaaagcaac accacagcat aagacaacaa attttgcaga
     1141 attggtttgc tctaactctt tccgtggaga tagcttgacc aatgctgtag ggcttctaaa
     1201 agaagaaatg cgtcgtttgg actctatcat tatgcgtaat ggagaagctc accgtgtgcc
     1261 agcaggtggt gccatggcgg tggaccgtga gggctatgca gaagcagtga cagctgaaat
     1321 tgaaagtcat cccttaattg aagttatccg taaagaaatc acagaaattc ctgatgatgc
     1381 tattacagtt attgcttcag gtcccctaac ttctgatgct ttagctgaaa agattcatga
     1441 gcttaacggt ggagacgggt tctatttcta tgatgccgct gcaccaatcg ttgataaagc
     1501 aactatcgac atgaacaagg tttaccttaa gtcacgctat gataagggtg aagcagctta
     1561 tctaaactgt ccaatgacca aggaagagtt catggccttc tatgaggcct tgactacagc
     1621 tgaagaagct cctttgaatt cttttgaaaa agaaaagtat ttcgaagggt gtatgcctat
     1681 cgaggttatg gctaaacgtg gtattaaaac aatgctctac ggtcctatga aaccagttgg
     1741 tttggagtat cctgaagatt atatgggtcc acgtgatggt gacttcaaga caccttatgc
     1801 ggttgttcag cttcgtcagg acaatgcggc tggtagcctc tacaatatcg ttggtttcca
     1861 aacccacctc aaatggggag agcaaaaacg tgtcttccaa atgattccag gtcttgaaaa
     1921 tgcagaattt gttcgttatg gggtaatgca ccgtaactct tacatggatt cgccaaactt
     1981 gcttaaacag accttccaat caaaatcaaa ccctaatctg ttctttgctg gacaaatgac
     2041 tggtgttgaa ggttatgttg aatcagctgc ctcaggtttg gttgctggaa tcaatgcagc
     2101 ccgtctcttt aagggtgaag atgaagttat tttccctcat acaacagcaa tcggtagcct
     2161 tccatattat gtgacacatg ctgaaagcaa acattttcaa ccaatgaatg ttaactttgg
     2221 tattatcaaa gaattagaag gcccacgtat tcgtgacaag aaagagcgtt atgaaaaaat
     2281 cgcagaaaga gctcttaagg atttgcaaac ttttatagat gcttgatgct aacataaaaa
     2341 gccctcacaa gagtgaaggc ttttcgtttt agagaggagc gaatagaaat atcgattagc
     2401 caaagaattt cttagcgatt tcttgacctt gtttgatttt agcccattgt tgaggtgttg
     2461 ccagctcatt acctgagtca catgaggcga aaccacattg gtgaaagggg aagagacgtt
     2521 tttttggaag gatttgactc gctttttcaa gcaaatcgag aacacgttct tcgtcatcta
     2581 ggtcagtcgt ttaagaagac aatagcccaa atacaacttc agctttactg tctttaaggg
     2641 cttccagagc tttgatatca ccagctgtat cgctatccca ttcaaggaag aagcggtcat
     2701 agtgttgctc tgccaagaat ttcttagcga tgtcttcgta agttccttca gaagcagaac
     2761 ggatttcata attaccacga cagttgtgtg tccaaaccgt taaaccaagt tcgtgagtat
     2821 agtcaacaac ctcattattg atagcaacaa attcatcggc caattctgcc aaatcaccat
     2881 tgccgtctga gtagaaactt gtagggtttg atgggtcaaa aagttcccag aggcagtcgt
     2941 caaattgaac gattttacca ccaacagcct tgtattcatc caagaattct ttataggcat
     3001 taatcaaacc ttttttgagt tcttcgtttg tttcatagac ttgtccagga acagccaatc
     3061 gatcaaagat agcaagttca gtgtaggcat gagcaggtcc ccagatagtt tgtttggtat
     3121 cttcatcacc agcttcagcc ttaaccaatt tgtaaatatc taggtagtgg tggtttttac
     3181 ctgatagagg ctcagtgata cgaataccga tatctttacg tgtttcatat tgaccaccat
     3241 catggtcttt aaaagtataa ccatgctcag caatgtagcg ttcaatacct ttgagtcccc
     3301 agacaaagtc caagtgccac atagaacgtc caaacttccc atcggtaagg atgtcaattc
     3361 cgttagcttt ttggtcagcc acattcgctt aatagatgca gtttcagttt cttgataacc
     3421 aggaagggca tcatagaaag gatactggat gtcgtcacga tgctcgattt cgtccttgta
     3481 tttacggaga tccgcaggac gaagaagaga accgactaat tggaatttag attttgtcat
     3541 taaatttacc tcgaaatgtc tatttacatc tatattattt cttatgggaa ctaatgaaaa
     3601 atagttaatt tcttgctgtg tatatagttt tagactatac aaggtttagc tctgcaaaat
     3661 gatacttctt atgataaaat ggaaagaaaa cgatgaaggt tgggaatatg caaaaaacat
     3721 tctttattat taaaccagat gctgttaaac gtcatctaat tggtcaagtg cttgatcgaa
     3781 ttgagcgacg tggcttcgtt attgagcgta tggagatgct gatgcttgac gaagaacgtc
     3841 ttaaagaaca ttatgcccaa ttggctgata aacctttttt ccctagtatt tctgaattca
     3901 tgatgagtgg tccagcagtt attggtatta tgtccggccc aggagttatt aagtcatggc
     3961 gtgatatgat gggagcaact aatcctgggg atgctgctcc tggaacgatt cgtggagact
     4021 ttgcaacagc accagatggt gacatgattc caaatatcgt tcatggctct gattcagaag
     4081 aatctgcggc tcgagaaatt aagatttggt ttggtgagta ggatggatat agcacagatt
     4141 caatcagaat tagctcagga tggactatta attgatgtca ggactccaga agagtacgca
     4201 gaaggtcatg ttaaggatgc tttattaata cctcacacgc agtttttcac agctgacatt
     4261 ccagctaaaa aagacgcctc catttacctc tattgtaaaa tgggatctcg tgctgaattt
     4321 gctgcaggag tactgaaaga acgaggatat actaaggtta ccaccttagg tggcctaggt
     4381 gatatggaag cactagggtt taagtttgaa aaataataca cataaggtca ctagtggtga
     4441 tcttatttgc tttcaaaaag catgacaaat tattaacaac gctttcataa agtggtaaga
     4501 ttctaaatga gttaagaaaa agcctatgaa aatgactttg ccagaacttg attaacttag
     4561 catattccaa ttgagatagg gcttgtggtt aagcttgtga ctacaattgg tagaggagga
     4621 tttcgtatgt caaaagttgc tattgttaca ggtgcaggtc aaggtattgg ttttgcgatt
     4681 tcaaaacgct tggttgaaga tggtgttaaa gtcggggtat tggactatga cgctgaaact
     4741 gctgaaaaag cagttgctga gttgtcagaa gacaaggcat tttccgttgt agcagatgtg
     4801 tctaaacaag ctgaggtagc agcagctttc caaaaagtag ttgatcactt tggcgacttg
     4861 aatgttgttg ttaataatgc tggtgtgtca ccaacaaaat cccttgacac tattactgaa
     4921 gaacagtttc aacgtacatt taacattaat attggtggag ttatctgagg tgcacaagct
     4981 gcccaagcac aatttaaatc acttggtcat ggtggtaaaa ttatcaatgc aactttacaa
     5041 gcaggtgtcg tagggaactc taacttaact gtatatggtg gaactaaatt cgtagttcgt
     5101 ggtattactc aaactttggc gcgtgactta gctgattcag gtataactgt aaatgcttat
     5161 gcaccaggta tcgttaagac tccaatgatg tttgacattg cccacgaagt tggtaaaatg
     5221 ctggtaaaga tgatgagtgg ggtatgcaaa cttttgctaa agatattacc ctcaaacgtt
     5281 tgtcagaacc tgaagatgtt gcagcagcag ttagcttcct agctggacct gactcaaact
     5341 acatcacagg tcaaacaatc atcgttgatg gtggtatgca attccattaa ggttaaaagg
     5401 gagagcgaat ggctctcttt ttttgcttga taaaacataa tgtttctgat aatatagtta
     5461 taaataatta tgtttttaaa ggtggattcc catatcagac atcttacact atattgctga
     5521 gcacccattt tttagtctta ttctattggg aattattgta ctagcctttg gtttagctcc
     5581 attttcaagt agttcaatag agaacaagcg ttcagctatt attaataagc actacaatga
     5641 taattttaag aaataagaag gactaaatgc agtcataaag cagatattag agataggcaa
     5701 atgcctgtct tttttgtata ataggaggtg acggttcgtt ttttaacaat cacaagtaag
     5761 aattaggaaa gaataaaatg ccaaatattg aagaattaaa acaaagacag gagaagattc
     5821 gcaacttctc gattattgct catattgacc atggtaaatc aacgcttgct gaccgtatct
     5881 tggaaaagac tgagactgta tcaagtcgtg agatgcaggc acaactcctt gatagtatgg
     5941 atcttgagcg cgaacgtggt atcactatca aactgaatgc cattgagctt aactacaaag
     6001 ctaaagacgg cgagacttat attttccacc ttatcgacac accgggacat gtggacttta
     6061 cttatgaggt gtcacgttcc cttgccgcct gtgagggtgc tatcttggtg gtagatgcag
     6121 ctcaagggat tgaagcacaa acacttgcca atgtttactt ggcacttgat aatgacttgg
     6181 aaatcttacc agttatcaat aaaatcgacc ttccagcggc agatcctgag cgtgtacgta
     6241 cagagattga agatgttatc ggattagatg cctcggaagc tgtgcttgca tcagctaagg
     6301 ctggcattgg tatcgaagag attctcgaac aaattgttga gaaagttcct gcgccccaag
     6361 gtgatgtgga agcacctctc caagccctta tctttgactc tgtttatgat gcgtatcgtg
     6421 gcgtcatact ccaagtgcgt gtggttaacg gaatggttaa aacgggcgat aagattcaaa
     6481 tgatgtctaa tggcaagacc tttgacgtta ctgaggttgg tattttcact cctaaagctg
     6541 ttggccgtga ctaccttgcg actggagatg ttggttatgt agcagcttca attaagacag
     6601 ttgcggatac tcgtgtcggt gatacagtga cacttgcgga taatccagcc gcagaaccac
     6661 ttcatggtta taagcaaatg aacccaatgg tctttgctgg tctttatcca attgagtcaa
     6721 ataaatataa cgacttgcgt gaggctcttg aaaagctcca attgaatgat gccagtcttc
     6781 aatttgagcc tgaaacgtct caagcccttg gttttggttt ccgttgtggt ttcttgggcc
     6841 ttcttcacat ggatgttatc caagagcgtt tggaacgtga gtttaacatc gatctcatca
     6901 tgactgcacc atcagtagtt taccatgtta acactactga cggtgaaatg cttgaagtgt
     6961 ccaacccatc tgaatttcca gatcctacac gtattgatgc cattgaagag ccttatgtca
     7021 aagctcaaat tatggttcct caagagtatg ttggtgctgt tatggagttg gcgcaacgta
     7081 aacgtggtga ttttgaaacc atggaatata ttgatgataa tcgtgttaac gttatctatc
     7141 aaattccact tgctgaaatc gtctttgact tctttgataa attgaagtca tcaactcgtg
     7201 gttatgcaag ttttgactat gaattgtcag agtaccgtcg ttcacaattg gtgaaaatgg
     7261 atattctcct taatggtgat aaggtcgatg cccttagctt tattgtccat agagaatttg
     7321 cctacgaacg tggaaaactt atcgttgata aacttaagaa aattattcca cgtcaacaat
     7381 ttgaagttcc tatccaagcg gctattggtc aaaaaattgt tgcccgtaca gatatcaaag
     7441 ctcttcgtaa aaacgtcttg gctaaatgtt acggtggtga cgtttcacgt aaacgtaaac
     7501 tcctcgaaaa acaaaaagct ggtaagaaac gtatgaaagc cattggttcg gtggaggtac
     7561 cacaagaagc cttcttgtct gtgctttcaa tggacgaaga tgagaaataa gaatgatagt
     7621 agaatgtgat gttctggcta ttttagtaaa aagttatgat aaagaggatt ttaaaattta
     7681 ccttctcaaa gtgtggaagg atttatgcta cgatcatact aaatactttt ctttttaggg
     7741 aatggcgata caaagcatgt agcagaatta tagactgacc taaaagcaga taaggtaact
     7801 tccaatgaga tttttggtag tcgtcaacaa tatgttgtac ttagtcatgt agaacacact
     7861 tactacatta cgataaacac tataaaatca gactttagag aatataaaga agctagatga
     7921 ggattcatgg ggggtagtct tatcaggaat cccttcgcaa gcatttttct cagctttagg
     7981 ctataatata caaaaggaaa gtcgggaggg ccactatgga tatcacaaat tttattccta
     8041 gtcagcgaca ggctatgttg gaacgttttc agcaagtgga ggccttgggc ttaggcgcag
     8101 ttcgtattga gttgaaggtt gcgaatcctg ttggcatcat ttatgagtgc tacattatgt
     8161 caggagagaa ttatttttct gatcaagcag tggtatcctt ccgtattctt tacgaaaagg
     8221 acttggaccg catttctttg gatgtggtag atatccctgg tcgctcaagt ttgtctaatt
     8281 atctccagtt actagagatt tttgaaggct tgcaacatta tcttaatcga gagtttgcta
     8341 aggtaaaaaa tacataaaca tctgattgta atcaggtgtt tctttttgtg ctggaagttc
     8401 aaaatttcac aatagtcaac ctccatttga taataattcc accaatcgtt acgattttcg
     8461 tcgaagaagt aactagtagg aatatgtgca aacgtctcag caattaaccg aatttgcaaa
     8521 gggttcaaaa aaccaactgc ttggaaccgc tttaaataca taaaatatcg tttagcgatt
     8581 agttatcctg gctcacctga tacattctta cgttctttgg ctagtttatg ccttttttgc
     8641 ttcatttttt tatgtttcat aactttttcc ttcctaattg actgacctat attgactttt
     8701 aatatcatat atgctataat tatatcaaat aatccctcaa aagggaaata aatgaaagaa
     8761 aggccttccg ctcgtcggaa aggtaatggt gtccaatgga caatactaag gatctctcaa
     8821 atccagaaac agcaagtaat aaagccccct ctaaactaac ctttatttat tatgacgaag
     8881 acgaatttgc agcgttttta gattccctcc ccttaactgt agcgtcaaag gttatcgcaa
     8941 ggatacgaga ggtttctgct atcggtatag cagaagccat ggctctaaag ttagtcagaa
     9001 aagtagatag aaaaaaagat atctttgagc ttagaattaa tacggaaggc attttcgccc
     9061 gttcattatt ttccgtttag aaaaagctaa cgaagaagaa gacaatgtgg cttcacctac
     9121 ttatatcatc acaaactcct ttaagaaaaa aacaaataaa acaccatcta aggaattgaa
     9181 gaaagctatc aaacgaaaat cgaactataa gaacaagcga tgacacaaac tggattctcg
     9241 caatccagtt ttaagggctg aaaaagattc aacctttaaa actggactgt aaagtttagt
     9301 atggatattg actataattt attaaggaga gatgcacatg aaggaaatca aacttacacc
     9361 acttgataaa gtggatagaa acgggtttct tgcttcatac ttggcagaaa ggagtaaaaa
     9421 ggaacctgaa attctacagc actataacaa tgaaatcgag tgtataaagc tatcgcataa
     9481 aattaaacaa ttaagagaga atatcaattt aactcagcaa gaacttgctg atcgtatggg
     9541 aaaaagtcag gctagtatcg gacgtataga gaatggcacc actaatccaa catataaaac
     9601 attggaagaa attgccgctg caaccaatac tagattagtt gttgactttg ttccaataaa
     9661 gaactagttt ttgtatacac tcaaaaagct ctataatctc tatagtggtt ttacctacta
     9721 cagaaatcat agagtctttt ttatattata cccttattag agaacaacat cataccttaa
     9781 ctacaccaca aaagttagac atcgaaagtc taacttttgt ggtgtcttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaatg
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtattga atcatcaaac
    10501 aatgatgctt ttatcaagag aaatgtgtaa acgttcagaa ttttacaagg atttaccaaa
    10561 ctaccgaagg ttacactcaa caatgctatt aaattgttat atcataagta ttgaaagaga
    10621 tgagtatatt gattcgttgt attttgaaaa acagttaaat catagttgtt ttacggaaac
    10681 tgagatttac gagaaattag tgtttcatta ttcaaaaaat ttatatgaat taaagaagaa
    10741 taggagcaat aaagctattc tagaaatgaa gaagtatatt gctgcaatga agctggctaa
    10801 tagtgagaat ttagctataa aatttgaaaa tcatttatct ggagtgttaa aaatgtagtt
    10861 ggatttgtgt atatggtata aattatcagt gtcaaaatta aatgatatat tattgatatg
    10921 agaattatta aatttcctga acagatttca gaagatatca ttcattatac gtttctagat
    10981 gatattatct cttataattg tgaaaagtgt agaggatctt gttgtcatgt gaataattct
    11041 ttattacttg atgcaaagac agcaagtttt ctaaaacgca cgtatcttaa agattttatt
    11101 gttagtgatg atagtgtttc attgttgagt tgtggtaaaa agtgctggtt tcattctgaa
    11161 ttgggttgta cgataaatga tttaggcttg aacaagccat taacttgtga attatatcct
    11221 tttcatatta agaaaattca gaacttctat attgtttctt ttactccttg tccgacattt
    11281 caactgaacc ttggtgaggg gcagaggtac aaggatatag aggatgtagt tttacgatat
    11341 attaaaactg gggtgccagt ttttagtccg tctttgcatg tttcagagga aaggctgaaa
    11401 tatgagattg agtatcaaaa caattttaaa aacactttat cagagtatta tcgaacaaag
    11461 actgccgatg gcactacaga gtttaaagaa tatgaaaaat ggtatatata ttatttagat
    11521 tttagatggg gaagtatacc cttatcttat acaagttcac aagcaaatca attttggaat
    11581 ctttacaaga gagtttgtga agatgtttat aaaaaaatat catatatacg aacagataac
    11641 atatacttta ttattgcaaa tcagtttaat aagacaattt caaagcattt tcagctaaat
    11701 tttatagata aagaatgatt tctatgattt gttatgggta cttattgatt cttaaataaa
    11761 taatggagga tattacgatg caagttagtg atgctattgc acaaattgaa ttagcagaag
    11821 aagaagttgt ttctagcggt ctatctattg acattatgga aattaaacct tctgttgcta
    11881 cagagttgat tgatggactc aaaggtcgtt gcccaccgtc tgtctaatag aactgattgt
    11941 aggattagag tctatttcta atcctttggt ttttatatta atatttttgg aagattgcag
    12001 ggaattaata tgacgagcaa tgtttactcg atttttttta attggtacaa taagcaagga
    12061 atactcagga ataataggaa taataaacta ttttcattaa atttagctac atttttagct
    12121 ttaaaattta tgtaccaatt ttcattgaaa aagttttctg attcaaagag tcaggtaata
    12181 aaaaatgtta tagattttct aaataacaat gaaatatcac tctctaagac caacactaaa
    12241 attgttgaat tttcaacgaa aataccatta aaagtgatac agattgaggt cacgaacaaa
    12301 tgtaacctaa gatgtatgca ttgttattta cctgattatt caaaggagct cgatagaaag
    12361 aaaatttcaa gtatagtata tgaagctaag cagctaggag taatggatgt tgatttcact
    12421 ggaggcgaac cattattatt acagggatta agtgaaatta tcgaggaagt attaaaagag
    12481 ggaatgtgta caacaatttt tacaaatgct gtatatattc ctgaagattt taaaatattg
    12541 attcaaagat atgatggtat aagactaaaa gttagtttag atggttggaa tgaaacaata
    12601 catgattcaa ttagaggaag aggtacattt aagagaacaa ttaagaatat tgaatatttt
    12661 aggagtttag gagtacctgt tactgttaat gttgttttga ataacaagaa tattagtgga
    12721 gtgaagtatt ttttggagtt gtttgatcga ttagatgtga aatatgcttt tgataggttt
    12781 ttaccttttg aaaggaataa tcgactatca attagtgatg aagaattcaa taatgctatt
    12841 ttgtgtattc ccaatattca agcaaattgt aataatatat ccgaatccac atttgaatca
    12901 ttttattgtg gtgctggcaa ttcttatgtg tttataaatt cgtcaggtga tgttggattt
    12961 tgtccgacat tatcctccac taaattttgt ggaggtaaca ttaatgaaaa gactttaaat
    13021 gatatttgga ttaattcgaa gttcttcaat catattcgaa atgtacgatg taagtattat
    13081 aatgaatgcc ctgcaaatta tgtttgtcaa ggtgggtgta gaagtcgagc tcagtttttc
    13141 ggaggttcta ttgggagtcc cgatatacag gagtgcaagt tagcatataa tttaactggg
    13201 attaagccaa agtcaatgag tttatgaaaa tattatctat tatttatgat ggtggaagta
    13261 gaattccagg agcgagattt gctcccacaa aatattatca agaagcgatg ttatatgata
    13321 ggaaagattc tgatataatt acaattaatt taggtaatca agatttattt tctattgatt
    13381 tagaaagtct aagtcgaact attgctgaat ctaaagttca gattgcttta ggaggagatc
    13441 attcagttac ttatctatta gcaaaggcca ctgttcgaga gggagcatat ttaattgttt
    13501 tagatgctca tttagattac ttcaaagact ttgaaagtgt tgtaaaaaat tggaattttt
    13561 taagtttttt aaccgatatt tttgaaaaaa taattatcat tggggaaagg aattttgagt
    13621 ttcctagttc atttgataat aaaataatca tcctctcaat ggaggagtat tggttaaata
    13681 agagtagagt tttgaaaaag ttagatagtt atattgatga gtcaaaagat atttacttat
    13741 caatagacat tgatgttttg gatccatctg tttttgattc agtatcatat cctattattg
    13801 gaggatttca aatgaacgat tttcttggaa taatttccaa aattttatgt tctgataagg
    13861 tatatttttg tgatatagtt gagtacaatc cgatggttgg aagtgataat gctcacattt
    13921 tttaccaaat gattcaattt gttaaatcaa aattaaggag gatataggaa atattgaaaa
    13981 taaaaaaata tgcagcattg agtatttatt ttaatcgttt ctcatcgtta atctcagagt
    14041 atggttatac tatcttgatc aacattctat tgtctagaat ttctgtgcaa ttagttatgt
    14101 atttttgggt ggtaaagtgt ttagctgcaa tagttacaaa taggattaat atctcaaata
    14161 gtaaactgag cagaaaatac ctgcttattc tgttagaaat tacaaaggca atcttacttt
    14221 tcttactagg ttttggatta aaccatataa ttgtcctatt agttgtattc ataattgagg
    14281 ttgtcaatgt attgttttcc agtttattat atagttgtgt accaattatt atagacaagg
    14341 attcattgat taagtttaac gctaggtata caagcattgg ttcagtatct tattttttag
    14401 caccgttgtt tgttggttta tttattaata aaagtcactt tttattgttt gcagtttatg
    14461 ctcttctttt gatagtggga gctactagtc ttttattttt accaaatatt tcgactttaa
    14521 atttgaaaga agaaagaaaa aaacaaaatt taaacattac attatttaac attctgagat
    14581 ccaaaaaaat tgcattagtt ctattatctg gagttattgt gggatcaatt ggagttgttt
    14641 atgatactta tgaagttgtt tatttaacaa agtatctcgg tattagtgat tctatgtatt
    14701 ccttttcctt atcattttta gcagtttcat tcttagtaat gagcttcctt cttagcttcg
    14761 tgaaacaaat aagttctcat atgaaagctt tcgccttagg tctttcattt tatgttctat
    14821 atctactttt atttagtaca tcttcgaaca tttatacagt actaatgagt tatgtttttc
    14881 tagcgatagg tcagacaatg atggggataa tcgaaaccaa ttattttcag ttgtcactta
    14941 acatgaaaga attacagaaa ctatatattt actcggagac cttacattct gtattttcag
    15001 gcattgctgt tttagtaata ggaagttttg cctttttaag tagtcatctt gttttagttt
    15061 tcagaagtct tgctgttttt gctctgttta ttcttctgtg ttattgtgtg tttgtaaacc
    15121 tcaaaaaact aagcattgat aagtaatatt tataaatcag aaaacaagca aatgagatag
    15181 ttaatttata aagtagacaa acgctatttt gagtatttgt ctttttttag tcacctagtc
    15241 tgcctttttt cacaagattg tctgaaaact gtgctataat gataacagaa ttgtgaattg
    15301 atgaaagttt gtgaaaaaac gagcagactt tgacactttg tgacttatac ttgaaaggaa
    15361 agttggctct accattttag ggctagaagg actgtgttca tgtcagaaga aaagcaattg
    15421 tatggtgcgg atttagtggt tgatagtttg atcaaccatg atgttgagta tgtctttggg
    15481 attccaggcg caaaaatcga tagggttttt gataccttgg aagataaggg acctgaattg
    15541 attgttgccc gtcatgagca aaatgctgct tttatggctc aaggtgttgg acgtattact
    15601 gggaaaccag gtgtagtatt ggtaacatct ggtccaggtg tctccaattt ggctactggt
    15661 ttggtaacag cgacggatga aggagaccct gttcttgcta ttggtggtca ggttaagcgt
    15721 gcagatctct tgaaacgtgc ccaccaatca atgaataacg ttgctatgct tgagccaatt
    15781 accaaatatg ctgctgaagt acatgatgct aacacccttt ctgaaacggt tgctaatgcc
    15841 tatcgtcacg ctaagtcagg gaaaccaggt gcaagcttca tttcaattcc tcaagacgtg
    15901 acggatgctc cggtcagtgt taaggctatt aagcctatga cagatccaaa acttggttca
    15961 gcatctgttt ctgatattaa ctatctcgca caagccatta aaaatgcagt gttgccagtc
    16021 tttcttttgg ggaatggtgc ctcatcagaa gccgtaactt actctattcg ccaaattttg
    16081 aagcatgtta aattgccagt tgttgaaact ttccaaggtg ccggtatcgt gtcacgtgac
    16141 cttgaagaag atactttctt tggtcgtgta ggtcttttcc gtaaccaacc cggagacatg
    16201 ttgcttaaaa aatccgactt agttattgcc attggttatg acccaatcga atatgaagca
    16261 cgtaactgga atgctgaaat ttcagcacgt atcatcgtta ttgatgttga gccggccgag
    16321 gtggacactt acttccaacc ggaacgtgaa ttgattggta atgtagaagc gagcttaaac
    16381 ttgcttttgc ccgctattca aggttataaa ttgcctgaag gttcggttga atatcttaaa
    16441 ggtttgaaaa acaatgttgt tgaggatgtt aagtttgacc gtcagcctga tgaaggtacg
    16501 gtgcatccgc tagatttaat cgaagttttg caagaacaaa cagatgatga tatgactgtt
    16561 acggttgatg ttggtagtca ctatatttgg atggcacgtt atttcaaatc gtatgaacca
    16621 cgtcatttgc ttttctcaaa tgggatgcaa acgctaggtg ttgctcttcc atgggctatc
    16681 tctgcagctt tggttcgtcc taagacaaaa gtgatttctg tttctggtga tggtggtttc
    16741 ctcttctcag cacaagaatt ggaaacagca gttcgtttga aattgccaat tgtccatatt
    16801 atctggaacg atggtcatta caatatggtg gaattccagg aagaaatgaa gtacggtcgt
    16861 tcatctgggg ttgactttgg tcctgtagat tttgtaaaat atgctgagag ctttggagcc
    16921 aaaggttatc gtgcaacaag taaagcagcg tttgctagct tgctccaaga agccttggct
    16981 caagctgtag atggaccagt ccttattgat gttccaattg actataaaga taacattaaa
    17041 ctcggcgaaa ctattttgcc agatgaattt tactaaaaag agggtgtaga catgtctgaa
    17101 gccataaaat tatttcaata taatactttg ggagccttga tggctgggct ttatggaggt
    17161 actttaaccg ttggagagtt gttagagcat ggagacttgg gtctcggaac attagattct
    17221 atcgatggtg agttgattgt tcttgacggt aaagcctatc aagctaaagg ctctgaaggt
    17281 aaagtcgaag tggtagaagt ttctcctgat gaaaaagttc cctatgcagc agtcgtacct
    17341 caccaagctg aagttatctt ccgtcaacgt tatgaaatga ctgataaaga acttgaggat
    17401 cgtattgaat catactatga tggggtcaat cttttccgtt caatcaaaat caaaggtcat
    17461 tttaaacaca tgcacgtgcg catgattcca aaatcaaatg cggacattaa gtttgctgat
    17521 gttgccactc gccaacctga gtatgaggta gatgatattt caggtacaat cgttggtatc
    17581 tggacacctg aaatgttcca cggtgtgagt gttgctggtt accatctcca ttttatttca
    17641 gatgacttga cattcggtgg tcacgttatg gattttgtta tcgagaatgg tattattgaa
    17701 gttggaccag ttgaccaact cgatcaacgc ttcccagttc aagaccgtca atatctcttt
    17761 gctaaattca atgttgatga aatgcgtaaa gatattacta aggctgaata agcatataaa
    17821 taagatactg tctctttgtc aactgtagtg ggtaacgaaa agctaacatc tagagaggac
    17881 cggataggtc ctttttttgg ctctttgtca actgtagtgg gtgacgaaaa gctaacatct
    17941 agagaggacc ggataggtcc tctttttatg tatgttcagt gtgatgaaga cacgtttctt
    18001 aaagttgatg aagtttctaa aaccgaagcc caagcgttta atgtctttaa ttaacttatt
    18061 agtcgcttca agttttgcgt ttgaatagtc tgtttctagt gcattttgga tgtattgctt
    18121 gtgtctaaga aaagtcctaa agaccgtttg aaaatagtga ttgaccttgc ttctattttc
    18181 ctctatcagg tcaaagaact cacctactct cttctcctga aagtgaaaaa gcaaaagctg
    18241 ataaagtgta tagtagtcag taagctcttt tgaaaagact agtgtcttct taacaacttc
    18301 atgtggtgct aaagtttggc ggaaagtctt tgaatagaaa gagttgagag ataacttaca
    18361 gctgtccttt tggaagagtc gccagtgatt tttcaaggct cgatagggta gtgacttctt
    18421 atcgaactgg ttcataattg caattctagt ctttaaaaag gcacgtccaa ggtgctggat
    18481 aatgtggaaa cgatcaagaa cgattttggc gtttggaaag agtctgcggg atagtgggat
    18541 ataggctcca gacatatcca tcgtgataaa ctgcacctgt tggcgagctt tcaatggata
    18601 cttcaaaaag tagtttcgta tagtagtttg gcagcgatta tcaaggatgg ttatgagttc
    18661 gtttgtctca tacttttgag ctacaaaagc caactcccct ttcttgaaac caaactcatc
    18721 ccaggacata acagcaggga gtttgtcata atgtttcttg aaagtgaact gatcaagctt
    18781 acgatagaca gtggacgtcg acacgcgaag tcttcttgca atatcagtta gtgacacctt
    18841 ctcagttaga agctgtgtaa ctttttgtcg gactagattg gagatttggc agtttttctc
    18901 aacgatagat gtctcagcta ccgtgactct tctacaactt ttacactgga aacgacgttt
    18961 tttcagacgt agtagagttg gcgttcccgc ttgctcgaga agagggattt tagaaggctt
    19021 ttgaaagtcg tacttgatca tctttccatg gcagtgagga catgatggtg cagggtaatc
    19081 gagttttgct tgaatctcga tatgagtatc agtttcaaaa acaagtgaaa tcttgatatt
    19141 ttggtcttta attccgatta attctgtggt attcttaata ggtctcataa gttcttccta
    19201 atggtagttt tgtcactttt cattatagtt cttattggac tttttgtgta cactcaaaaa
    19261 gctctataat ctctacagta gttttaccca ctacagaaat tatagagcca agatactccc
    19321 ctattcgaca taggggagta tcttgtttta aaacgacgaa gtggtcctaa ctcttccgtt
    19381 ttatttatta agttatagca tatctcactc aacagatttt agagcctcga gcatattgac
    19441 tttcttaagg tgttggttca caaagatacc cagaacctgt cagaatgata atgattacta
    19501 gtgttggaac agcgtagatg agccagccaa gatttggatt gaacataata ttttcaggtg
    19561 ggataacatc taccatgtat tgatgcagtc ccaaaccaag tccgaattca accaagatac
    19621 caatgataga aagacaaatt gtttctcgat agatgtagag cgtcacttct ttattaaaga
    19681 aacctagaac cttaatggtt gataattcgc ggatacgctc tgccacattg atattcgtta
    19741 aattgaagag aacaacaaaa gcaagaagaa tagaaacact aatcaaaact cccataacac
    19801 ggctaagtga gttgacgatg gtcttgattt gtgcctttag agtagtattt tggacatccc
    19861 cttttacacc atcaagagac ataaatcgac tggctgtttg ctcaacattt ttgtctgaat
    19921 gatctttcag tgtaagtatc gtagcatttt ggctagcctc ttttccgaaa gcatccttat
    19981 aagtagattc gttcataaag atgaagtacc ccatgtacat ctcagaaata ccagcaactt
    20041 tgagtttgat gtctttgtcc tggctatttt gaacggttac ttcatcacct acagaaatac
    20101 cagctaggtc cgccaatttc tctgagataa taatgccttt ttcagtcaaa tcaagcttct
    20161 gaccagtttc acgatgattg agtttgatgt aattttgaag tgttttttga tctttatcat
    20221 tgacaacaag tgttgtgata tcttgacgat cgttattact tcctacatct aacaggtgct
    20281 acggacggta tcggtaagca tctagcaaag aaaccgtcta gtgaaggcta tcatatcatc
    20341 ctccacggtc gcaatcctca aaagctggaa ttggctactc aggaggttcg ggcagtctcc
    20401 ttgagaggca gagtgtctag ctacttggct gatttttcaa aattagataa tgtttatcga
    20461 tttgtggagg aaatcaagcg agactttcaa aggattgata tcttatttaa caatgcaggt
    20521 ctgtatgcag ggaaagagcg aaaagcgagt ggtgaaaatg tcgaactaac tttcatgtta
    20581 tccgttctgg ttccctatat ttttataaca gagctaatcc ccttgttaga aaaattgcct
    20641 gatggccttg ttatcaatac ctcttcctat atgcaccatt ttgcgaaagt gaaggatttg
    20701 gactttggct ttgagaaaga atacaatccc ggtttggcct acaataattc caagctctac
    20761 accatttgga tgacacgcta tctagcaaga gatttctttt taaaaggttc aaataccact
    20821 attaatgcct atcatctcgg cttgatttta accaacttag ggaataattc tagtgataaa
    20881 aagacggaaa agtctctctt cggacgcttg atgaagtctc tttcaaaaga tctagatcag
    20941 ggaatcgaaa caggctatta tctcacctta tcagaggaag tcagtggctt gactggctac
    21001 tactttgatg aaaagaaagt caagtcggta tctgaaaaag tctactcatt tgaaaaaaca
    21061 cagaaattaa tgaattactg ccaagaaaag gtcaaaatgt ttaaagaaaa gcagaatgtt
    21121 taatatcata aatataagaa aaaagctcaa gttttcatta ataaaacttg atcttttctt
    21181 atacaagagt taataaaatc gtaattacca gagcgattcc gatccgaatc aggtagtggg
    21241 ctactagatg gaaatttcct ttatgcttgc cattccaata ggctccgtag caaatcaagc
    21301 taactccgat cagccaaagg aataaagcaa caattggcaa aaggaagtaa aggatgagag
    21361 aaggtcgcaa ggttgcttcc gataaggaga agccgatttc ctagagtatt cttgtgcttt
    21421 cttaattctg aaagactggc cattacatta aatgaagaag agcaaaagca agggataaga
    21481 aagctgtgaa aataccaaga agaatgagga ggagcatagt tttcctttct atgatacatg
    21541 atgtaaagtc gcaccttagt tagaagcgac gtttaaaatc tccaaataaa actggactac
    21601 ttcctgctcg ctgtaggact tgcctttttt caaccaccag gtcagggttt caatgaagtt
    21661 ggttacaacc aggtgcttga gatatgagtg aggaatgttg gggtgtgatt gaatcagttc
    21721 atcagctacc attggataga cgtcatgttc cagttctttt cgcagctgcc ggataaaata
    21781 atcgtttttt gaaagcaaga gactggttac atggtcttga tttttcttga aatgttgaaa
    21841 gatatgggcc aggtagtctt gtggagagag gtattgagta cgctcaaaca aatggtgaaa
    21901 gagcttttgg cagagctcat ccagtagtaa ctctttgctc tcataatggc tgtaaaaggt
    21961 cgaacgcccc acatcagcca agtcaataat ctcctgaacg gtgatggcct cataatcttt
    22021 ttggttaagt aagtacaaga aagcttgata gatggctttt ctagtcttgg taatgcgacg
    22081 atcttgtgca gtcatatgga cactataaac aaactgttca gtaacgtaca cagcgaacgg
    22141 tttgccccta tcctttctgt tggtagtatt ggataataga tattgaatat gatgttcgtg
    22201 aatctattat accaaaggaa ggtaaaaaat gagttcaaaa tatgcagtct ggttggcttt
    22261 tttcttgaat ctaagctttg ccattgttga gtttattgca gggggaatct ttgtttccag
    22321 tgctgttctc gctgactctg tccatgactt gggggatgct ctagccattg gcctctcggc
    22381 ctttctagaa acaatctcca atcgtgaaga agatagtcgc tataccctag gctacaagcg
    22441 ttttagctta ttaggggctt tggtaacggc agtcattctg atgacagggt ctggtatggt
    22501 gattttagaa aatgtaagca agcttttcca cccacaaccc gtcaatgacg aagggcttct
    22561 ttggttggga attattgcta tcagtgtcaa tctgctggcg agtctggtca ttcgtaaggg
    22621 tcagaccaag aatgagtcta ttctcagcct gcattttttg gaagatacct taggttggtt
    22681 ggctgtcatc ctgatggccg ttgtcctccg atttacggac tggtatatcc tagatcccct
    22741 cttgtctctt gctatttcct tctttattct gtccaaagcc attccacgtt tttggagcac
    22801 gctcaagatt ttcctggatg ttgtgccaga aggggtagat atcaagcaag ttaagaatga
    22861 cttagagcag ttggataatg ttgctagtat caatcagctt aatctttgga ccatggacgg
    22921 cttggagaaa aatgctattg tccatgtttg tctggagcat gtcaaacata tcgaggtctg
    22981 taaagagtct atccgagact tgctcaaaga gagtggcttt caaaatgtca ccatcgaagt
    23041 tgatgaagac ttggcaaccc accaagctca caagcgaaat atcgaagagc tagaagcaga
    23101 aagtgagcag caacaccatc attaaggttt gtttttaaac tcttagagtc tacctttaag
    23161 agttattttg ataccaagtt ccctaaagtg atccttttca tgataaaata gaacaaatgt
    23221 agaacaa
//
