LOCUS       c00036_gnlPro..        16523 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DHDEFLCF_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 23:28:33
            Original ID  :: gnl|Prokka|DHDEFLCF_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16523
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16523
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3278:6523]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3279..6523
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16523
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16523
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..278)
                     /locus_tag="ctg36_1"
                     /transl_table=11
                     /translation="LSDQQAFADIFAHLWIKLKLYSILLHMAEQWLNQHHRSFFINTSP
                     RQGQLFSRILTLSKRKHTFEVKSVSTQNYSKLIHTMLPALPDYIQDY"
     CDS             complement(1224..2156)
                     /locus_tag="ctg36_2"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVLDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELINAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
     CDS             complement(2186..3154)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg36_3"
                     /sec_met_domain="LysR_substrate (E-value: 3.6e-27,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 1.2e-19, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             complement(3279..4130)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_4"
                     /sec_met_domain="Radical_SAM (E-value: 6.3e-26, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             complement(4165..4296)
                     /locus_tag="ctg36_5"
                     /transl_table=11
                     /translation="MSLLGPSSKKCKQLNSRQEAIPVLPKDGNDAVAVFWQNEMKIN"
     CDS             complement(4262..6523)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_6"
                     /sec_met_domain="Gly_radical (E-value: 9.5e-42, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.5e-244, bitscore:
                     802.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDEVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             complement(6775..8364)
                     /locus_tag="ctg36_7"
                     /transl_table=11
                     /translation="VTKATXXXXXGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNM
                     VAIADMQPKLLGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQV
                     IAAIRASKDKGDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIA
                     EYQDILARPAARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQV
                     SRDGYVKRSSLRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEI
                     SDARWKDTGEHLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQ
                     RTYKSKPMMAMKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATG
                     VKSMDLKPDDEVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLREL
                     KRDPHRIVAMMSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVF
                     VQTKEEPADQVE"
     CDS             complement(8327..9229)
                     /locus_tag="ctg36_8"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVIAAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDXXXXXXA"
     CDS             complement(9236..11248)
                     /locus_tag="ctg36_9"
                     /transl_table=11
                     /translation="MDKATQAYNDSSIQVLHGLEAVRKRPGMYIGSTDGRGLHHLVYEI
                     VDNSVDEALAGFGDEINVTIHADNSVTVQDHGRGMPTGMHPSGKPTIEVILTVLHAGGK
                     FNQNSYKTSGGLHGVGSSVVNALSESLTVRVVRDKHAFEEHFINGGHPDGSLQKLGKVN
                     EPNGTTITFKPDPTIFQTTVFSYDTLAERLRESAFLLKNITINLTDERTGKHDSYHYPD
                     GLVSFVKYLNEGKDALSQVINFEGKKDGIVVDFAGQYNDGYSENLISFVNNVRTGDGGT
                     HEIGLRSGMTRAFNEFARKVGLLRERDKNLEGSDVREGFAGILSVRIPEEILQFEGQTK
                     GKLGTPQARTVVDGIVYDKLSTFLMENGEESQELVRKAVKARDAREAARKARDDSRTGR
                     KRKKDQGLLSGKLTPAQTKNPKRNELYLVEGDSAGGSAKQGRDRKFQAILPLRGKVLNT
                     QKAKLQDIVKNEEINTMIYTIGAGVGADFDLQQANYDKIIIMTDADTDGAHIQILLLTF
                     FYRYMRPLIDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKGYTLTRF
                     KGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGDRVEPRREWIEHNVKF
                     DMDDDGSILETPTANHEKLQFGAKQIVKQLDKKGK"
     CDS             11843..12550
                     /locus_tag="ctg36_10"
                     /transl_table=11
                     /translation="MYVRFILLTYHSKVKNAKIVSSLRGGAHLILVLCFILAYFIGAIP
                     FGVVIGKLFYHTDIRKGGSHNIGTTNAYRMLGPVGGSIVLVLDILKGTLAASLPILFGI
                     EHHWLVLIVGLAAVFGHTFSIYIRFKGGKAVATSAGILLAYNPPFFVIAFAIWFSLILL
                     TSMVSVASTLGMVLITAWSLVYHDWLLTTVACGLLVVFLIKHRANFKRIKAGDENMVPF
                     GLGQYLRQHRGRS"
     CDS             complement(12632..13510)
                     /locus_tag="ctg36_11"
                     /transl_table=11
                     /translation="MVTIANDFLTVKISRHGAELTSIKDNLTGRERLWQADPAVWGRHA
                     PVLFPIVGALADNQYHYAGKTYHMGQHGFARDRDFTVLSATPFKASFVLKDDDKTRAMY
                     PFAFRLIITFALENNNLHVTYHVDNPDKSEPLFFSIGGHPGFKVPMTPDTQFSDYYLNF
                     KPRKSLVQIPLVAGEGIDYTHRTLAATDANLALTHETFDHDALIFALLGKTTFNLVSDK
                     TKHGVSVTMTDTPYLGVWSPYPTTGDFVCIEPWWGIADTIGSTGDLTRKLGINRLEPGT
                     AFEKGYMISIF"
     CDS             complement(13546..14784)
                     /locus_tag="ctg36_12"
                     /transl_table=11
                     /translation="MAEVQTPKQIVEKLDQYVIGQDDAKRAVAVALYNRYRRMQLSPKM
                     QEEITPKNLLMIGPTGVGKTEIARRLAKIVEAPFVKVEATKFTEVGYVGRDVESMVRDL
                     AETAVAMEEEKQFSKVRIRAEKEANKRXXXXKGLLEDHEITVAVNDEKKGGGMGDMYGQ
                     MGIDLSDTIGALMPKKKVERTMTVKEAREIFIKEESDKLVNHADIYHDAIQSAENNGII
                     FIDEIDKIAAGNKHNSGEVSREGVQRDILPIVEGSQINTKYGPINTDHILFIGSGAFAE
                     AKPSDLIAELQGRFPIRVELKDLTEKDFVRILTEPDNALIKQYIALIGADGVKITFTKE
                     AVDRIAEIATQVNHDTDNIGARRLATILEKLLEDVLYEGPDMAMGSVTVTQQYVDDKIG
                     HIAADSNMTRYIL"
     CDS             complement(14828..15352)
                     /locus_tag="ctg36_13"
                     /transl_table=11
                     /translation="MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVV
                     IGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHD
                     LLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDI
                     FTNHNVIVESF"
     CDS             complement(15600..16496)
                     /locus_tag="ctg36_14"
                     /transl_table=11
                     /translation="MKPIAAFQEYLEVERQYSPETVTAYLSDLQEFQAFLKANGGFTDF
                     RHVDDLDVQTYLTDLNKQDLARTSIARKISSLRSFYRYLTRIDVVKRNPFELVELKKQH
                     HHLPQFFYEAEIQELFKTVAGKTPLDQRNRALLEVLYGTGIRVSECAKLTLNQVDFNTA
                     LLLIHGKGNKDRYVPFGQYAQQALRTYLKDGRQVLMAKSQAQHRYVFVNQYGRPITSRG
                     IEYILDQLIKQTTLTANIHPHMLRHSFATHMLDHGADLRTVQELLGHASLSTTQIYTHV
                     TMAHLKNEYMKYYPKHN"
ORIGIN
        1 taatagtcct gaatgtaatc cggcagggca ggtagcattg tatgaattaa tttcgaataa
       61 ttttgtgtcg acacagattt cacctcgaac gtatgttttc ttttagataa tgttagtata
      121 cgcgaaaaca actgtccttg gcgagggcta gtgttgatga aaaatgaacg gtggtgctgg
      181 ttcagccatt gttctgccat gtgaagcaga attgaataaa gttttagctt tatccaaagg
      241 tgagcaaaga tgtcagcaaa cgcctgttgg tcagacaaat tttagctcac ataattctgg
      301 tatgaattcg gctattaaat gagttcactt cggtcaatca ttcagcaaac ttattttggc
      361 cattggtcaa taaaataaat ttgctgaatg ttgcgtgacc ctcaattgtt gttgagtcaa
      421 tttcaaacta cacaactcaa aaaatcatca gtcaactcga agccggctaa ctgacgagaa
      481 tctcacaaca tcatgaagct tgaattgata tgcatttttc tggttttggc tggcatgaca
      541 ttttcaatca aacaaatgca tgcaacacag cgcaaacgca acgtcccaag tcataattga
      601 ttgccttggt aaaaagttca atagccacca cagccaccac caacattacg tccgaaccac
      661 aaatttttga cagccatctg aaagagggga cacccagatt cgcagatcaa gtgccaaagc
      721 caattattta tattctagtt tacataatat atattatgcg aagcagtgtt tgaagagacg
      781 gcatcgtgcc attctcgcaa tatttacgtt ggcgattatt tgattcgcaa tttcatccag
      841 cacccgatag tcgccgcatt tttttaaccg ctgcttgcag ccaagtcttt aaaagcttct
      901 acaatcattg gaaatcattc gatatttttt tgcttgagtt ttttcgttaa gtcaacaact
      961 atcaagttga attcccgaac tcgtctcaga atgcgtctct caccatgcct caaaaccatc
     1021 caaaatgacc catgacaact tgctgttgat tcgacccgcg aattactaca cgaatttcaa
     1081 attcacgcat cacgagttgc tagtcagctt tatatttaac agatttcgca aaaagatggc
     1141 tagagacttt ttgcaaacaa aaaagccgca actggctagc tgcgactttc cttagaacaa
     1201 ttgtgtgcaa ttaaagatga aagttaacct tcaaacgtgc tctgcattgg cggaacgacc
     1261 tgctttttgc gggaaacaac cccaggcaat gccaaacgcg cgtccttgtc gaactgttcg
     1321 ttaaaagcac tggcgatttt atcgcggtca gcaccgactg cgaaaccagt tgaattgctg
     1381 tccaagatgt cagtagcaat cagcaggaaa tcgtcgtagc ctttcgcctg cgcctctttg
     1441 gtcatggcat tgatcaattc gtcctgacgt gcgtaaatgt cgttcagatc gacggtattg
     1501 acctgtccga tgcgaataga cttgccgccc atggtgaaac tcttagcatc gccttcgata
     1561 atgtccatat ctgacttggc ggccaaatta gtgcctgcct tcagcatggc aagaccatat
     1621 gactgcaaat caattccggc aatcttcgcc atttctggca aaatcttctt atccttatcg
     1681 gttgcggtcg gcgacttcaa caacagcgtg tctgaaatca aaccagaagc catcaaacca
     1741 gccaatgttg gcgaaatctt gaagccatat tcctggaaca tctcaaaaat gacggtattg
     1801 gtgctgccaa ccggttctgc tcggtaaaac agcggcgctg ccgtgtggaa gttagcgatg
     1861 cgatgatggt cgacaacaga atcaatcgtc acgtcttcga tatcactgac actttgttga
     1921 aattcgttgt gatcaaccaa catgacatga tccgtctcgt tggctgccgt cttgataacc
     1981 cgcggtgcct gaaccttgaa gtgatcaagg acgaacttag tttcatcgtt cggttcgcct
     2041 aatgctaccg cctcaacatc cgtgttgcct gcctgtttct gaaattctgc ccagctcatg
     2101 gcactcgtaa tcgcgtcggt gtccgggttc tgatgcccaa aaatcaaagt cgtcatctta
     2161 tctgatcgct cctcaactga ataatttact tatcaagttt aacacggttt tcactgaccc
     2221 gcgacaagta atctttttcc ttcagataat cgtcaaaggt ctggaagaag ttcgagatcc
     2281 gcggaatgtc agctttctct ttgcgataaa caaaagaaat ctcaaagcga atggccggat
     2341 caaacgcaat agcataggcc ttgatttgat cagcgcgtgc ccgaacaaaa ctggttggta
     2401 aggccgtgtt gacccctgac aagttaacga attgggttaa ctgatatggc gtggtgaaat
     2461 gtgcgaccac gtgcgggaaa tcaaccattt gattcttgta cgcctcacgc agaagctgtc
     2521 caaggaaata gtcgtcagga taagttgccc aaggttcagc taaagtatct ttgaaatgga
     2581 ttcgcttacg gttagccaag gcgtcatcgt ggtgcaagaa cagcaattgt tcatcaataa
     2641 ttttcttgct ggcgtatggt ttccagttct taatggtttc atctggcaga ttcatgatag
     2701 ccaaatcaat ctggttgttt tccaatgatt cccaaatttc gtgacgggtc atcatccgta
     2761 gcgttacttc aacttcagga ttcagttgat agtaatgagc aatgaacgca ataaaggcgc
     2821 tatcctcgat tgagcttaat aacccaatat tgatttttcc gacggttgca ctggttgttt
     2881 gttgaatttc gtcggttgtc tggttcaaga tctcgtagat ctcatgggtt gactttaaca
     2941 tggtctgacc agcgtcagat aaatgcagtt tcttcccgac agaataaaac agcggtgccc
     3001 ccactgtccg ttccaatttc ttgatctgct gtgttaaggc tggctgggta atgccaagca
     3061 attgggcggc ttgggtgtag ttcatggttt ctgccaattg cagaaaataa gttagtgtct
     3121 ttgaggaaaa aatgcgctct tgtttcgttt tcatagggcg gcttcccttt cgtttattat
     3181 ttaataatat cgttcaacca tcatcataag tggcaatgaa aaaaaacgca acgaatttgc
     3241 cgcgttttta atcgttacgt taagttctag ctaaaaattc agttgctcgc aactggtttc
     3301 ggacgccagc tttgccatcc ggtataatcc ttaacgtgca gcagattctc tgcattctta
     3361 acgcgatcgg cagacggcgg ttcgatgcct tcaagcgggt acgtaatgcc aagctcgtga
     3421 tactttttaa cgcctaacgt gtgatacggc agaatctcaa ctttttggac cacgtttttg
     3481 tccaatgtcg caatatagtc ccctaatcgt ttgagataag ggtcaaagtc agtgcgttcc
     3541 gggaccagaa cgtggcgaat ccacatgtca tcaccatgcg ccgacatata ctgcaccata
     3601 tctaaaatat tttcattagg aaaaccggtg agctttttat gctcggccga atcgatgtgt
     3661 ttaatatcaa ctaatgagat gtcagtaaca gccatcagct tttcaaactg gccaaaccac
     3721 ggttggtcac gcgtgaaggg gccgcctgac gtatcgaggc aagtcgaaat tcccagtgcc
     3781 ttagccttgg tgaagagttc gagaatgaaa tcgatttgta ccaaactctc accgccactg
     3841 cacgtaatac ccccttggtc accccagaat gctttatagc gctgggcatc cgccaaaatt
     3901 tgatcggccg tcatttcttc accaacccca atgttccagg tgtcagggtt gtgacaatac
     3961 tggcaacgca tgcgacaccc ttgcataaag acaacgaagc gaataccagg gccatcgacc
     4021 gaaccaaaac tttcgaccga gtgaacatac cctttgatcg ggccatcatg atcctgacca
     4081 acttgttcta agatatttaa tgggctttgt gactgatcga tgagtttcat cttattgcct
     4141 ccactacaac atcatgtgtc gttttcaatt gattttcatt tcattctgcc aaaaaacggc
     4201 aacagcatcg ttgccgtctt ttggcaaaac aggaatggct tcctgtcttg agttaagctg
     4261 cttacatttc ttcgaagaag gtccgagcaa tgacatcgtc ttgttgttcc ttggtcaaat
     4321 ctgcgaagta gacgcagtag ccagaaaccc gaacggtcaa tgttgggtat tcttctgggt
     4381 gcttctgagc atcaatcagg gtctccttgt tgaagacgtt gatgttcaaa tgcatgccgc
     4441 tgttttccat atagccgtca accatgtgaa ccaaggtatc cttacgagtt tcatcatcgt
     4501 ggcccagtgt gttcggagta accccaaacg tattactaat gccgtcagtt gcgtaatgat
     4561 acggaatctt ggcggtggac atcaaggatg ccaatgcgcc gttcttttct gcgccgtatg
     4621 ccgggttggc acctggtgag aatggttcgc ctttttgacg accgtttggt gttgtccctg
     4681 tattcttacc ataaaccacg ttggaagtaa tggtcaggac actggtactc aacttcgcgc
     4741 cgcgatacag atgatgcgtg ttcatcttgt tatagaaggt cttaaccaac cacttagcga
     4801 tgtcatcagc gcgatcatcg ttgttaccat aacgtggata gtcatcattg tcagcaacga
     4861 agtcaactgc aacaccgttt tcatcgcgaa ttgccttgac atgaccatac ttgattgcac
     4921 tgatggaatc aaccgcgtgt gacaggccgg aaatcccggt tgcgaaggtc cggttcagtt
     4981 gggtatcctt caatgccagc tgtgcagctt cataataata cttgtcatgc atatagtgaa
     5041 tcacattcaa agcattgaca tacgtgtcgg ccagccagtc catcatcttg tcgaacttat
     5101 tcatgaattc tttgtaatca atgtaatcgc tggtgatcgg tgcatattca ggccctactt
     5161 gcgcttcctg aatttcatct ttaccaccgt tgatcgcata cagaaccgtc ttagctaagt
     5221 tagcacgggc accaaagtat tgaacgccat cagcaattgg ttgtgccgag acacagcaag
     5281 caataccgta gtaatcggta ccccattcat tgcgcatcag gtcatcattt tcatattgaa
     5341 tggttgaact ttggatggat acttcggttg catagcgttt aaagccttct ggcaagcgtt
     5401 cgctccaaag caaggtgatg tttggttctg gtgctgcgcc catgttgtcc aaagtcttca
     5461 ggaaacggaa agccgtcttg gtaacgtggt gacggccatc attgcccatt cctgccaatg
     5521 acaaggttgc ccagattgga tcgcctgaga acagtgagtt atattcttca gtccggatga
     5581 aacgaaccat ccgcaatttc ataaccaaat gatcaatcag ttcctgtgcc tgttcttcgt
     5641 tcaatttgcc taagcgcata tcgcgttgga tataagcatc aataaccgta tcgatccggc
     5701 caacggacat tgcggcaccg ttttgagtct taacagcagc cagatagcca aagtagatcc
     5761 actgaacagc ttcttgcgca ttagctgccg gacgcgagat gtcatagcca tattccttgg
     5821 ccatcttctt catgtcgttt aaggcacgat attgttcatt gatttcttca cgcaatttga
     5881 ttacttcgtc agtcatttcg ccgtcgccgg tcaagttata atccttgaac ttctcagcca
     5941 ttaaacgatc gatcccgtaa acagcgatcc gtgggaaatc agaaacaatc cggccgcggc
     6001 cgtatgcgtc tggcaagcca gtcacgatct tgtaatggcg agcctttcgc atatcagggg
     6061 tataagcatc aaagacacct tggttatggg tcttacgata ttcattgaaa atcttgtgtt
     6121 cttgaggatc tgtcttgaag ccataagatt ccaatgcatc ttcagccatt cgaataccgc
     6181 caaatggcat gaatgctcgt ttgaatggct tgtcggtctg aacaccaaca atcttttcaa
     6241 gatctttgtt caaataacca gggccgtgtg aggtgatcgt agatggaata ttgttgtcag
     6301 catccaaaac accgccattt gcacgttctt gcttctttaa atttagaacc tgattgttca
     6361 ggactgttgt cgcttcagtg gggccagcaa ggaaactttc gtccccgtca tattggttca
     6421 ggttatgctc gataaaatcg cgcacattaa tttcttcttg ccagtcgccg ccgttaaagc
     6481 cttcccaata attaggaact ttggtttcgt caagctgttt catagttgtt tgcctcctaa
     6541 agtggattac agatgtgaca gttcttacaa acacagtata acacgccgcc aaatctatgc
     6601 aagcgcttca ttgcccatat aataggcgtt atattgtttt ttaagtgtgc ttcgtcgctt
     6661 cttttcgccc atgatttcgg cattttgtta aattgtgcac aactggtctg tcctataata
     6721 atcaaaaacg ccaccatctg tattagtaca gacggcggtg tcaatgatca ccatttattc
     6781 gacttgatct gctggttctt ctttggtttg aacaaaaact ggcttgccaa ggacatcagt
     6841 gtcaatgaca aacgaaccat tcgaatagcg gtcacctgct ggatgctgtg ccggattaag
     6901 ggtcgttacc ttacccgtat cggtcaaaac attcaggcgg gtagcgtcat cgactgacat
     6961 catcgcgaca atccgatgcg gatcacgctt aagctcacgc aagaccagta aaccacgacg
     7021 ggcacgactc atttccccga cttcgcttaa ggccatcttt ttgaaggcgc cacgttgggt
     7081 caaaataccg accttagccg tagttggatc cttcactaga atgaaattga caacctcatc
     7141 gtctggcttt agatccatac ttttaacgcc ggttgcccgg gcaccgacag ttgacacatc
     7201 gcttaacggg aatgtcagtc cgtaagcgtg gcggctgacc acaaagacat cctgttgctg
     7261 atcagtcgtg aagtatgcat tggtgacaat cgcggctggg tctttcagct tcatcgccat
     7321 catcggctta ctcttgtacg tccgttgcgg ctgcaaatca cttaaggcag tttgtttgat
     7381 gtacccgtca cttgacccta acacaaaact gccagcgcca tcgagttgat caaaagcaaa
     7441 cactgccaag actttttcgt cagtgccaag gccaactgtt tggcttaagt gttcgccggt
     7501 gtctttccaa cgcgcatcac taatttcatg cactggtcga taaatgacat ttccggcatt
     7561 tgtcacgatg taaagatgct gcaacgtact cagttcgcca gtgaaaatgg caagatcatt
     7621 ggccttcaaa ccattgtcgg ccggatcaac cgcctgataa ctgcgcagtg aactgcgttt
     7681 aacgtaccca tcacgagaaa cctgcaccat gacggtttca tcagccaccg tcaccgttgt
     7741 cgccacttca agtgtttcaa ttttggcttg aatgctgctg cgacgatcat ccccgtactc
     7801 cttggcaatc cgcttcaact cgccttcaat cacccgatcg cgggcagcgg ggcgggccaa
     7861 aatatcttga tactcggcga ttgctttcgc caattgtgct gcttctttct gtaaagccgt
     7921 gatatcggta ttggtcaatc gatacagctg caaggaaaca atcgcttccg cctgagcttc
     7981 cgaaaaatca aacttcttga ctaagttacg cttagcatcc cctttatcct tggaagcacg
     8041 aatcgcggcg atgacctgat ccaaaatcga tagcattttg atcaagcctt cgacaatgtg
     8101 ctgtcgagca gcggccttgt tgaggtcaaa acgcgttcgc cgagtgacca catcgcgtcg
     8161 atgctcgacg tatgcttcca acatggcctt aagtcctagc aacttcggct gcatgtcggc
     8221 aatagcgacc atgttaaagt tgtatgcaat ttgtagatcg gtatttttaa ataaatagtt
     8281 taagatgcca tgtgcatcgg cttctttttt taattcgatg acaacgctaa gcccnnnnnn
     8341 nnnnnnnnnn gtcgctttcg tcacggactt cggcgatacc gtccactttt ttgttgatgc
     8401 gtaattcatc gattttttta atcatctgcg ctttattgac atcatacggg atctcagtga
     8461 ccacgatctt ctcacgaccg ccacgaatgg tttcgatgtg tgtccgagaa cgaaccacga
     8521 ttttaccgcg gccggtttcg taagcttgct tgatgccatc aagcccttga ataatcccac
     8581 ctgttggaaa atcgggaccc ttgacgtatt gcattaaagt atctaaatca gcagtgggat
     8641 gcttcagcaa gtataagacg gcggcaataa cttcccgcag attgtgcggc ggaatttcgg
     8701 ttgcataacc ggcagaaata ccggtggcac cgttcaccag caaatttgga aacccagctg
     8761 gcagcacagt cggttcctgt gccgtgtcat caaagttcaa caccatatcg acggtttcct
     8821 tatcgatgtc ggccagcatt tccttgctga ttttgcttaa acgcgcttcc gtgtatcgca
     8881 ttgcagctgg cggatcacca tccatggaac cgttattccc gtgcatctga atcagtgggg
     8941 cccgtaactt ccaatcctgg cttagccgaa ccatcgcttc ataaatggag ctgtcgccgt
     9001 ggggatgata attacccatg acattcccga cacttttagc cgacttgcgg aagcccttat
     9061 catacgtatt gccatcttgg ttcatcgcaa ataaaatgcg acgctgaacc ggtttgaggc
     9121 cgtcacgcac atcaggcagc gcccgttctt gaataatgta tttcgagtac cggccaaacc
     9181 ggtcgcccat gacctcttct aaggtcagtt cttgaatctg attggccaat ggcttttact
     9241 ttcctttctt gtccagttgt ttgacgattt gcttggcacc aaactgtaat ttttcgtgat
     9301 tagcagtcgg ggtttccaaa atactgccgt cgtcatccat atcaaacttg acgttatgct
     9361 caatccattc acgacgcggc tcaacgcgat cacccatcaa agtggtcacg cgtcgttccg
     9421 ccagctgagc atcgtcaatc cgaacccgga tcaaagtccg cgtctcagga ttcatagtcg
     9481 tttcccaaag ctggtcggca ttcatttccc caagtccttt aaatcgggtc aatgtgtaac
     9541 ccttgcccat ggccttggtc tctttggcca actcttcatc ggtccaagca taactgatct
     9601 tggttttagc accagcgcct ttttgcagcc gatacaatgg tggcaaagca atgtaaattc
     9661 ggcctgcgtc aatcagcggc cgcatgtagc gataaaagaa ggttagtagc aaaatctgaa
     9721 tatgcgcgcc atcagtatcc gcatcagtca taataatgat tttgtcgtag ttggcctgct
     9781 gcagatcaaa atccgcaccg acaccagcgc cgatggtgta aatcatcgta ttgatttctt
     9841 cgtttttaac gatgtcctgt aacttggcct tctgggtatt cagtactttc cctcgcaatg
     9901 gcaagatcgc ctgaaacttt cggtctcggc cttgtttagc tgaaccaccg gcagaatccc
     9961 cttcgacgag atacaattcg ttacgcttag ggttcttggt ttgcgccggg gtcaatttac
    10021 cggaaagcaa accttggtcc ttcttgcgct tgcgtcccgt ccggctatcg tcgcgcgctt
    10081 ttcgagccgc ttcccgcgca tcacgggctt tgacggcttt acgaaccaac tcttgcgact
    10141 cttcaccgtt ttccatcaaa aaagttgaca gcttgtcata gacaatccca tcgaccacag
    10201 tgcgggcttg cggcgtacct agcttgccct ttgtctggcc ctcaaattgc aaaatttctt
    10261 ctggaatgcg gacacttaaa atacctgcaa aaccttcacg cacatcactg ccttcaaggt
    10321 tcttgtcgcg ttccctcagc aagccgactt ttcgggcaaa ttcattgaat gctcgcgtca
    10381 tgccgctgcg caagccaatt tcatgcgtcc cgccatcacc agtgcgaacg ttattaacaa
    10441 acgaaatcag gttttcagaa tagccatcgt tatattggcc ggcaaaatca accacgatac
    10501 cgtccttttt gccttcaaaa ttgatcacct gtgacaatgc gtctttgcct tcattaaggt
    10561 atttaacaaa actgaccaag ccatcaggat agtgataact gtcgtgctta ccggtgcgtt
    10621 catccgtcag attaatcgta atatttttca gtagaaaggc tgattcgcgc aagcgttcgg
    10681 ccaaggtatc ataactgaag acggtggttt gaaaaatagt cgggtccggc ttgaatgtga
    10741 tggtcgtgcc attaggttca ttaactttgc ccaacttctg caaactgcca tcaggatgac
    10801 cgccattgat aaaatgctcc tcaaatgcgt gtttatcccg cacaactcgc acagtcaatg
    10861 actccgatag ggcattgacg acgcttgagc caaccccatg caaaccacca gaagttttgt
    10921 aactattttg gttaaatttt ccgccggcat gtagcacggt taaaatgact tcaatcgtcg
    10981 gtttaccact cgggtgcatc cccgttggca tccctcgacc atgatcctgc acggtcacag
    11041 agttatcggc gtgaatcgtc acattgatct catccccaaa ccccgcgagc gcttcatcga
    11101 cagagttgtc cacgatttca tagaccaagt gatgcaaacc gcggccatcg gtggaaccaa
    11161 tatacatccc cggacgcttc cgcacagctt ccaagccatg cagcacctga atggatgaat
    11221 cattatatgc ttgcgttgct ttatccatag taaactccct tttttgaaca actaagttat
    11281 agaatacacc acgcgttgag atttcagaaa taaaaaataa gagcgcgagc cagcccgatt
    11341 agaaaccgga gcataagcgg ccttgggtgc gatggttggg ctttgaccat tgtgcccaag
    11401 gtccttatgt gcaggtttct gggctggcga gcgcgtttca atagagcagc ccgattagaa
    11461 accggagcat aagcggcctt gggtgcgatg gttggacttt gaccattgca cccaaggtcc
    11521 ttacacgcag gttgctgcga gtgcgtttag gcatcaacac catcaacagc agacctcaac
    11581 gtattgctct caggactcct gttttctcct caaaatcgac ccagctggct aataccatca
    11641 ttgttcattt aaattttatt agccgtgtca atgtcccaaa gctcagcaga aaaccgcact
    11701 tccctaagca tggcacataa ctatgacttc ttgacgtgaa attcatcgcc cgctggcacc
    11761 atatctacgc tgtgccccgc catgatcctt gcgcaagaca acaccaaatc gcgccacaac
    11821 ccgcttcaca ggttttattc gaatgtacgt tcgttttatt ctactgacgt atcactcaaa
    11881 agtcaaaaat gctaaaatag tttctagttt gagaggaggg gcacatttga tacttgtgct
    11941 ttgttttata ctcgcgtatt tcataggcgc catcccgttt ggtgtggtca ttggtaaact
    12001 cttttatcac acggatatcc gcaaaggcgg gagtcacaat attggcacca caaatgccta
    12061 tcgcatgtta gggccagtcg gcggctcaat tgtcttggtg ctggatatct taaaaggcac
    12121 gttggctgcc agcttaccca ttctctttgg catcgagcat cattggctgg tgctgatcgt
    12181 gggtttagcg gccgtattcg gtcatacatt ttcgatctac attcgcttta aaggcggtaa
    12241 ggcggtggca actagcgctg gcattttact tgcatataat ccgccatttt ttgtcattgc
    12301 atttgccatc tggttcagtt tgatcttgct aacgtccatg gtcagcgttg ccagcacact
    12361 gggtatggtg ttgatcacag cttggtcgct tgtttaccat gattggttgc tgacaactgt
    12421 tgcctgcggg ttgctggttg tctttttgat caaacatcgg gcaaacttca aacgcatcaa
    12481 ggccggagat gaaaatatgg tgccctttgg cttaggccaa tatcttcgtc aacaccgggg
    12541 ccgctcttag tcaccttttg atggcaacca aaaagacatc cgaaactgga tgtctttttt
    12601 tcatgtacct aatcgacaaa ctgatgacac cttagaaaat gctgatcatg taacccttct
    12661 caaatgccgt gccaggttca agtcgattga tcccgagttt gcgcgtcagg tcgccagtgc
    12721 tgccaatcgt gtcggcgatg ccccaccaag gttcgatgca gacaaagtcg ccagtggttg
    12781 gatacggact ccaaacgccc agatatgggg tatcggtcat ggtaacgctg acaccatgtt
    12841 tcgtcttgtc agaaaccaag ttgaaggttg tcttaccaag caacgcgaaa attaaagcat
    12901 catgatcaaa tgtttcgtgc gttaaggcca aattggcatc agttgcagcc aaggtccggt
    12961 gcgtgtaatc aatgccttca ccagcaacca atggaatctg aacaagcgac ttacgcggtt
    13021 tgaagttcaa ataataatcg gagaattgag tatccggcgt cattgggacc ttgaagcccg
    13081 gatggccgcc gatgctaaag aacagtggct cacttttgtc cggattgtca acgtgatacg
    13141 tgacatgtag attgttattt tctagtgcaa acgtgatgat taaacgaaaa gcgaacgggt
    13201 acatcgcccg cgttttgtca tcatccttca gaacgaagct cgctttaaac ggtgtcgcag
    13261 agagcaccgt gaaatcacga tcacgggcaa aaccgtgctg gcccatgtgg taagtcttgc
    13321 ctgcgtaatg atattgattg tcagccagcg ccccaacaat cgggaacaag accggggcgt
    13381 ggcgacccca caccgcagga tctgcttgcc acagacgctc cctgcctgtc aggttatctt
    13441 tgatactggt cagttcagca ccatgccgac tgattttaac tgtcaaaaag tcatttgcaa
    13501 tcgttaccat acatcctcat cctttaccta caacattatt gttaactaca aaatataccg
    13561 cgtcatgttt gaatcagccg caatatggcc aatcttgtca tccacatatt gctgggtgac
    13621 ggtcacactg cccatcgcca tatctggacc ttcataaagt acgtcttcaa gcagtttttc
    13681 aagaatggtt gccagtcgcc gcgctccaat attatcagtg tcgtggttga cctgagtcgc
    13741 aatctctgca attcgatcaa ccgcttcctt cgtgaaggta atcttcacgc catctgcacc
    13801 aatcaaggcg atatactgct tgatcaaagc attgtctggc tcggtcaaga tccgcacaaa
    13861 gtctttttcg gttaagtcct tcaattcaac ccgaattgga aaacgccctt gaagttcagc
    13921 aatcaaatca ctaggcttag cctcggcaaa cgcacctgag ccaatgaaca agatgtgatc
    13981 cgtattgata ggaccatact tagtgttaat ctgcgatcct tctacaatcg gtaaaatatc
    14041 tcgctgcaca ccttcacgcg aaacttcgcc gctattatgc ttgtttcctg cagcaatttt
    14101 atcgatttca tcgatgaaaa tgatcccgtt attctcggca ctttgaatgg cgtcgtgata
    14161 aatgtcggca tgattgacca gtttgtcaga ttcctctttg atgaagattt cgcgagcttc
    14221 tttgacggtc atggtccgct caaccttttt cttaggcatt aaagcgccaa tagtgtcgct
    14281 tagatcaatg cccatctgac cgtacatgtc acccatgcca ccgccttttt tctcatcatt
    14341 gacagcaacg gtgatttcat gatcttcaag taatcctttn nnnnnnnnna aacgcttgtt
    14401 ggcttctttt tcggcacgta tgcgaacctt tgaaaattgc ttctcttctt ccatggcaac
    14461 ggcagtttcg gcaagatctc ggaccatgga ttcgacatca cggccaacgt agccaacttc
    14521 cgtaaactta gtcgcttcca ccttcacaaa tggcgcctca actattttcg ccagtcgtcg
    14581 tgcaatttcg gttttcccga caccggttgg tccgatcatc agtaagtttt tcggggtaat
    14641 ctcttcttgc atttttggcg ataattgcat tcgccgataa cggttataca aggcaaccgc
    14701 gacggcccgt tttgcatcat cttgtccaat gacatattga tcgagttttt caacgatctg
    14761 ttttggggtt tgtacttctg ccatcataag cctcctgtag gtcaatgtaa ttgccgacgg
    14821 ttacaaacta aaagctttcg acaataacat tgtggtttgt gaaaatatcg atattccctg
    14881 cgatattcac tgcttctttg gcaatgtcag ctggtgtcat atctggggca tgccgcagca
    14941 tcgcgattgc cgcggcttgc gcaaagttgc cgccggagcc gatcgctacc acgtcttcat
    15001 ctggatctat cacttcgcca gacccggata caagtaacag gtcatgctca tccatcacga
    15061 tcatcatggc ttcaagtttc tgcaaggtcg gatccttgcg ccaatcttga gccagcgcaa
    15121 ctgcggaacg tcgcaagttg ccagcataat gctccagctt cttttcaaac cagtcttgca
    15181 gggtgaaagc atctgccacc ccgccggcaa atccgatgac gacttgatca tgatagatcc
    15241 ggcgaacttt ctgcgcgttg cctttcatga tgaccttttc gccaagggtt acctgaccgt
    15301 caccggccaa agcggtcaca ccatcttttc ttactgctgc aattgttgtc atagtcatgc
    15361 tcctttttaa gtgagcgcga gcagaagcgc ttagaaaccg gagcatacgg gggctgcaag
    15421 cctaaatggc tgaattttgg ctatttaggc ttgcaggtca ttatgtgtag gtttctgcga
    15481 ctgcgagcgc gttatctgcg tatctcgtcg gataaaaaca gctaaagtag cgattaatct
    15541 gttatcgcca atgttcttag cttaaaaaac tcagactgct tttgcatcat gctttagtct
    15601 taattatgct tcggataata tttcatatac tcatttttta aatgtgccat ggtgacatgc
    15661 gtgtagattt gtgtggttga taaacttgca tgacccagta gctcttgaac agttcgcagg
    15721 tcagcaccat gatccagcat atgggttgca aaactatgcc gcagcatgtg gggatgaatg
    15781 ttagctgtca gcgtcgtctg cttgatgagc tgatccaaaa tatattcaat gccacgcgag
    15841 gtaatcggac gcccatactg gttcacgaat acatatcgat gctgtgcctg acttttagcc
    15901 atcaagactt gtcggccatc ttttaaataa gttcgtagtg cttgctgagc gtactgtcca
    15961 aagggcacat acctatcttt gttgccttta ccatgaatca acagtaatgc cgtattgaaa
    16021 tcgacctgat tcaatgtcag tttggcacac tcggaaactc gaataccggt gccatacaaa
    16081 acttccaaca aagcgcgatt acgttgatcc agcggggttt tgccagcaac tgtcttgaac
    16141 agttcctgaa tctcggcttc atagaaaaat tgtggtaaat gatgatgctg cttttttaat
    16201 tcaaccagct caaatgggtt gcgtttgacg acatcaattc gtgtcaaata acggtaaaag
    16261 cttcgcaaac tactgatttt tcgggcaatc gatgtccgtg ccaaatcctg tttgttaaga
    16321 tcagtcaaat aagtttgaac gtctaaatca tccacatgcc gaaagtcagt aaacccgccg
    16381 ttggccttga gaaacgcctg aaattcttga agatcactca aataagccgt cactgtttcc
    16441 ggtgaatact gccgttcaac ttcaagatac tcttgaaacg ctgcaattgg cttcattgaa
    16501 tccctccgat aatacattaa cat
//
