LOCUS       c00054_gnlPro..        14384 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MENDNHPA_54.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 22:19:14
            Original ID  :: gnl|Prokka|MENDNHPA_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14384
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14384
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8009:11254]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8010..11254
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14384
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14384
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             3..362
                     /locus_tag="ctg54_1"
                     /transl_table=11
                     /translation="VGPLPTVISDSQWLHFIFEQLLTNAIKYTPHGSIKIYAKGDAVMV
                     ADTGIGILAEDLPRIFEQGYSGYNGRANQKASGLGLFLSKQIAEKLGLTLTVTSEIGQG
                     STFAIHFPQTRWQVE"
     CDS             456..1226
                     /locus_tag="ctg54_2"
                     /transl_table=11
                     /translation="MSTLLKLKNIEKTYTSRGAQPVRALTNISFTVEAGEFVAIMGESG
                     SGKSTLLNLIATLDDPTGGDISLNGQDLSNVKEGARAKFRREHLGFIFQDFDLLDTFNV
                     QDNIFLPLVLAKKPLEIMRNRLTKLAPRLGIDALLKKYPYELSGGQQQRVAAARAMITE
                     PEILLADEPTGALDSKTSTELLDLLTDVNAENRQTILMVTHSAVAASHSRRVLFIRDGQ
                     IFHQLYRGDLDQPAFLTRISETMTAMLTKAGDGQ"
     CDS             1223..3214
                     /locus_tag="ctg54_3"
                     /transl_table=11
                     /translation="MKFYFKLAASNLKADRRLFVPFVTTTSFLMAVNLIMLNAYASSDV
                     LFKKLGAAASKSLFMFGTDVIVIISVILAIYANNFLRKQRIRQLGLYNIIGFGKGELGK
                     MMAVEKLLLLLTTLLFGGILGTVLSRISYLALAKMLKVDHNLDFGLSQQAFSIAGIITI
                     GLFVVLLLVDELWLIRKRPIEIVRAQRAGEREPKTKWVTLIVSLIALIAGYYIAVTTTN
                     PLQAMSMFFVAVILVICGTYGLFTAGSVFVLKWLRNRKNYYYKPKHFINVANLLYRMQQ
                     NGAGLASIAILVTMTLITLASTATLFFGINEVVNTNTPVDLSYVLKANDTTAPGKVARM
                     ASANHVIIKSQHTFVGPSSTMALLDGNRLESQANVNGPFSMGNARSVQLMTIESYNRFT
                     GHHARVKSGEVLIYTSKNFPSKTIRIGQKTYRIRKRAGSFPNAQATFIPNLFIAFPEEK
                     QMIDAMQHLRNARYQNASDAQADITTSQDVMLQGSHANQLKLYEAVVKSRIAESASVQS
                     KAVNYDETMSIMGSFLFLGIIFGVTFILATLLILYYKQLSEGYADARRYTILQRVGLSL
                     REVRATINSQLLMLFYLPLLVAGIHVGFALPFIQRIMILFGLPNWQFFLTVSLITLGIF
                     AIIYVLMYKLTGNVYYRIVSRRQATSRS"
     CDS             complement(3283..3636)
                     /locus_tag="ctg54_4"
                     /transl_table=11
                     /translation="VLDVKDSVNRLAWTTEHHFLHIQARHDFMRAWAVQFEMAYTDFRV
                     IQMALQLGGEQYHDLLKRFAAAYEAVYAYEYAFAAGGLAGFDEQFADKMADYQTAEQTL
                     LKIIDEIKALQPA"
     CDS             complement(3743..4855)
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="VSTQNYSKLIHTMLPALPDYIQDYYQSQKAIPIADSTLYQYLHFY
                     QEFLNWLINSGVTAASSPQTVPLTVLEHLSLRDAQAFMAYLLERPSKTHHNKRMTRRSV
                     ALRLVGIKALYRFLTEESEPHADGEPYFYRNVWNKVKLKTHTETASYRNHKLQEMLFVD
                     GEDAKFLQWLDQSYAQQLPAKPRRYFEATKVRNLAMIALLFGSGVRVSELVNMNLEDLN
                     MDRHTVQVVRKGNFQDRVNFADWIDPYVQAYLTQRAAIIGYQKPTSPLFVTVVGQKINR
                     IRQNTIEAFFKRYTTDYGRPSTPHKARHTLGTNIYTVTKDVQQVADQLGQTTTSATDLY
                     INLSDKSGKEALREVSETAAKATDRGHDQA"
     CDS             complement(5955..6887)
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MTTLIFGHQNPDTDAITSAMSWAEFQKQAGNTDVEAVALGEPNDE
                     TKFVLDHFKVQAPRVIKTAANETDHVMLVDHNEFQQSVSDIEDVTIDSVVDHHRIANFH
                     TAAPLFYRAEPVGSTNTVIFEMFQEYGFKISPTLAGLMASGLISDTLLLKSPTATDKDK
                     KILPEMAKIAGIDLQSYGLAMLKAGTNLAAKSDMDIIEGDAKSFTMGGKSIRIGQVNTV
                     DLNDIYARQDELINAMTKEAQAKGYDDFLLIATDILDSNSTGFAVGADRDKIASAFNEQ
                     FDKDARLALPGVVSRKKQVVPPMQSTFEG"
     CDS             complement(6917..7885)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     60.8; E-value: 3.2e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg54_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.7e-27,
                     bitscore: 85.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 5.6e-20, bitscore: 60.8,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKQERIFSSKTLTYFLQLAETMNYTQAAQLLGITQPALTQQIK
                     KLERTVGAPLFYSVGKKLHLSDAGQTMLKSTHEIYEILNQTTDEIQQTTSATVGKINIG
                     LLSSIEDSAFIAFIAHYYQLNPEVEVTLRMMTRHEIWESLENNQIDLAIMNLPDETIKN
                     WKPYASKKIIDEQLLFLHHDDALANRKRIHFKDTLAEPWATYPDDYFLGQLLREAYKNQ
                     MVDFPHVVAHFTTPYQLTQFVNLSGVNTALPTSFVRARADQIKAYAIAFDPAIRFEISF
                     VYRKEKADIPRISNFFQTFDDYLKEKDYLSRVSENRVKLDK"
     CDS             complement(8010..8861)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 65.2;
                     E-value: 2.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_8"
                     /sec_met_domain="Radical_SAM (E-value: 2.9e-26, bitscore:
                     82.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLIDQSQSPLNILEQVGQDHDGPIKGYVHSVESFGSVDGPGIRF
                     VVFMQGCRMRCQYCHNPDTWNIGVGEEMTADQILADAQRYKAFWGDQGGITCSGGESLV
                     QIDFILELFTKAKALGISTCLDTSGGPFTRDQPWFGQFEKLMAVTDISLVDIKHIDSAE
                     HKKLTGFPNENILDMVQYMSAHGDDMWIRHVLVPERTDFDPYLKRLGDYIATLDKNVVQ
                     KVEILPYHTLGVKKYHELGITYPLEGIEPPSADRVKNAENLLHVKDYTGWQSWRPKPVA
                     SN"
     CDS             complement(8993..11254)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_9"
                     /sec_met_domain="Gly_radical (E-value: 4.4e-42, bitscore:
                     132.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-244, bitscore:
                     802.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLDETKVPNYWEGFNGGDWQEEINVRDFIEHNLNQYDGDESFL
                     AGPTEATTVLNNQVLNLKKQERANGGVLDADNNIPSTITSHGPGYLNKDLEKIVGVQTD
                     KPFKRAFMPFGGIRMAEDALESYGFKTDPQEHKIFNEYRKTHNQGVFDAYTPDMRKARH
                     YKIVTGLPDAYGRGRIVSDFPRIAVYGIDRLMAEKFKDYNLTGDGEMTDEVIKLREEIN
                     EQYRALNDMKKMAKEYGYDISRPAANAQEAVQWIYFGYLAAVKTQNGAAMSVGRIDTVI
                     DAYIQRDMRLGKLNEEQAQELIDHLVMKLRMVRFIRTEEYNSLFSGDPIWATLSLAGMG
                     NDGRHHVTKTAFRFLKTLDNMGAAPEPNITLLWSERLPEGFKRYATEVSIQSSTIQYEN
                     DDLMRNEWGTDYYGIACCVSAQPIADGVQYFGARANLAKTVLYAINGGKDEIQEAQVGP
                     EYAPITSDYIDYKEFMNKFDKMMDWLADTYVNALNVIHYMHDKYYYEAAQLALKDTQLN
                     RTFATGISGLSHAVDSISAIKYGHVKAIRDENGVAVDFVADNDDYPRYGNNDDRADDIA
                     KWLVKTFYNKMNTHHLYRGAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPA
                     YGAEKNGALASLMSTAKIPYHYATDGISNTFGVTPNTLGHDDETRKDTLVHMVDGYMEN
                     SGMHLNINVFNKETLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVIARTFFEEM
                     "
     CDS             complement(11506..13950)
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="LANQIQELTLEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRI
                     LFAMNQDGNTYDKGFRKSAKSVGNVMGNYHPHGDSSIYEAMVRLSQDWKLRAPLIQMHG
                     NNGSMDGDPPAAMRYTEARLSKISKEMLADIDKETVDMVLNFDDTAQEPTVLPAGFPNL
                     LVNGATGISAGYATEIPPHNLREVIAAVLYLLKHPTADLDTLMQYVKGPDFPTGGIIQG
                     LDGIKQAYETGRGKIVVRSRTHIETIRGGREKIVVTEIPYDVNKAQMIKKIDELRINKK
                     VDGIAEVRDESDRFGLSVVIELKKEADAHGILNYLFKNTDLQIAYNFNMVAIADMQPKL
                     LGLKAMLEAYVEHRRDVVTRRTRFDLNKAAARQHIVEGLIKMLSILDQVIAAIRASKDK
                     GDAKRNLVKKFDFSEAQAEAIVSLQLYRLTNTDITALQKEAAQLAKAIAEYQDILARPA
                     ARDRVIEGELKRIAKEYGDDRRSSIQAKIETLEVATTVTVADETVMVQVSRDGYVKRSS
                     LRSYQAVDPADNGLKANDLAIFTGELSTLQHLYIVTNAGNVIYRPVHEISDARWKDTGE
                     HLSQTVGLGTDEKVLAVFAFDQLDGAGSFVLGSSDGYIKQTALSDLQPQRTYKSKPMMA
                     MKLKDPAAIVTNAYFTTDQQQDVFVVSRHAYGLTFPLSDVSTVGARATGVKSMDLKPDD
                     EVVNFILVKDPTTAKVGILTQRGAFKKMALSEVGEMSRARRGLLVLRELKRDPHRIVAM
                     MSVDDATRLNVLTDTGKVTTLNPAQHPAGDRYSNGSFVIDTDVLGKPVFVQTKEEPADQ
                     VE"
     CDS             complement(14090..14383)
                     /locus_tag="ctg54_11"
                     /transl_table=11
                     /translation="IDAGRIYIALPPLYRLQKGAGAKTKISYAWTDEELAKETKAMGKG
                     YTLTRFKGLGEMNADQLWETTMNPETRTLIRVRIDDAQLAERRVTTLMGAAS"
ORIGIN
        1 ctgtggggcc attgccaact gttattagtg acagtcaatg gctgcatttt atttttgaac
       61 aattgctcac caatgccatt aaatataccc cgcacggttc aattaagatt tatgccaaag
      121 gggatgctgt catggtggcc gacaccggta tcgggatttt ggccgaagat ttaccgcgga
      181 tttttgaaca aggttattcc ggctacaacg gccgcgcaaa tcagaaagct agcggtttgg
      241 ggctattttt gagcaaacaa atcgctgaaa agcttggctt gacgctaact gtcacctcag
      301 aaattgggca aggcagcaca tttgccattc attttcccca aacgcggtgg caagtggagt
      361 aagctacctt accagcttgt aagcaactac gagtcactgt aagtaggcat ggggcatcat
      421 ccccgctaag ctaataaatg aaaggggacg atcacatgtc aacattactt aaattaaaaa
      481 atatcgaaaa aacttatacc agtcgcgggg ctcagccggt gcgtgccttg acgaacatca
      541 gtttcactgt tgaagccggt gaatttgtgg caattatggg tgaatcaggt tctggcaaaa
      601 gcaccttgct aaatctgatt gcaacgctgg acgatccaac cggcggcgat attagtctaa
      661 acggacagga tctgagcaac gtcaaggaag gtgcccgggc taagtttcgt cgagaacacc
      721 tcggtttcat ctttcaggat ttcgacttgc ttgacacctt caatgttcaa gacaacatct
      781 ttctcccatt agtccttgcc aagaagcctc tcgaaattat gagaaatcgg ctaactaagc
      841 tcgcaccacg actaggcatt gatgccttgc tgaaaaaata tccttacgag ctttccggcg
      901 gccaacaaca gcgcgtggcg gcagcgcgcg cgatgatcac cgagccagaa attttgttgg
      961 ctgatgaacc caccggcgcc ttggattcta aaacttctac agaactgctt gatctgctca
     1021 cagatgtgaa tgccgaaaac cggcaaacga tcctcatggt aacgcacagt gctgtggcgg
     1081 ccagtcacag ccgacgagta ttatttattc gcgacggtca aatttttcat caactttatc
     1141 gtggggatct cgatcaacca gcctttctaa cccgtatcag cgagacgatg accgccatgc
     1201 tgacaaaggc aggcgatgga caatgaaatt ctactttaag ctcgctgcaa gtaacttgaa
     1261 agccgatcgc cgcctgtttg ttccgtttgt caccaccact agcttcctga tggccgtcaa
     1321 cctaatcatg ctgaatgctt acgccagtag tgatgtcttg tttaaaaagc tgggggcagc
     1381 cgctagcaag tcactgttca tgttcggcac agatgtcatc gtgattatct ctgtgattct
     1441 cgccatctac gcaaacaatt ttctgcgcaa acagcgtatt cgtcagttag gactttacaa
     1501 catcatcggg tttggcaaag gtgaactcgg caaaatgatg gcagtggaga agctgctact
     1561 gttactaacc actttactgt tcggtggtat tctcggtacc gtcctttccc gcatcagcta
     1621 ccttgcgctc gccaaaatgc tcaaagttga ccacaatctt gactttgggt taagccagca
     1681 agccttcagt atcgccggga tcattaccat cggcttattc gttgttttgc tgttagttga
     1741 tgaactttgg ctcattcgca aacggccaat cgaaatcgtg cgagcacaac gagcaggtga
     1801 gcgggagccc aagacaaagt gggtgacgct aattgttagc cttatcgcct taattgccgg
     1861 ctactatatc gcggtcacaa caactaatcc actacaagca atgagtatgt tttttgttgc
     1921 cgtgatctta gtcatctgcg gcacttatgg actgttcacc gccggatcgg tcttcgtctt
     1981 aaaatggttg cgaaaccgca aaaattacta ttacaaaccc aagcatttta tcaatgtagc
     2041 taatttactc tatcgtatgc aacaaaacgg cgctggtctt gcatctattg ccattttggt
     2101 gacgatgacc ttgattacgc tcgccagcac ggccacgttg ttcttcggta tcaatgaagt
     2161 cgtcaatacg aatacgccgg ttgatttgtc atatgttctc aaggcaaacg acaccactgc
     2221 acccggcaag gtggcacgga tggccagcgc gaatcatgtc atcatcaagt cgcaacacac
     2281 ttttgttgga ccgtccagta cgatggcttt acttgatggc aatcggcttg aatcgcaggc
     2341 caatgtcaat ggtccgttca gtatgggcaa tgcccgctcg gtgcaattga tgaccattga
     2401 gagctacaac cgctttaccg ggcatcatgc ccgcgttaag tcaggggaag tgttgatcta
     2461 tacatccaaa aattttccta gcaagaccat tcgcattggt caaaagactt acaggatcag
     2521 aaaacgtgca ggtagctttc caaatgcaca agcgactttt atccccaatc tttttattgc
     2581 ctttcctgaa gagaagcaaa tgatcgacgc catgcagcat ctgagaaatg cacgctatca
     2641 aaacgcgtct gatgcgcaag ctgatatcac cacaagtcaa gatgtgatgt tgcaaggaag
     2701 ccatgccaat cagcttaagc tctatgaagc ggtggtcaag agtcgtatcg ctgaatcggc
     2761 ctcagttcaa tcgaaagccg tgaattacga tgagaccatg agtatcatgg gcagctttct
     2821 tttcctcggc atcattttcg gcgtcacctt cattttggca accttattga tcttgtatta
     2881 taaacagtta tctgaaggct atgccgatgc ccgccgctac acgatcttac aacgcgtcgg
     2941 cttaagcttg cgagaagtgc gcgcaaccat caacagccag ttactaatgc tgttttatct
     3001 gccattactc gtggcaggga ttcatgtcgg atttgcattg ccattcattc aacgcatcat
     3061 gatattgttt ggcttaccga attggcagtt cttcctgact gtctcactca tcacactagg
     3121 gatcttcgcg atcatctatg tcctcatgta caagctcacc ggtaacgtgt actatcgcat
     3181 cgtctcgcgt cgccaagcta ccagtcgcag ctaacgaaaa aaagcgtcga aacgccagta
     3241 aaaatactgt cgctcgacgc tttttttcgt tgatgccagc aattaagccg gctgcagtgc
     3301 cttgatttca tcaatgatct tcaacaatgt ttgctcagct gtttgatagt ccgccatttt
     3361 atcggcaaac tgctcgtcaa aaccagccaa cccgccagca gcaaaggcat actcataggc
     3421 atacaccgct tcgtaggcgg ccgcaaaccg ctttagcaaa tcatgatatt gttcgccgcc
     3481 aagttgcagc gccatctgaa tcacgcgaaa gtccgtatac gccatctcaa attgaactgc
     3541 ccatgcccgc ataaaatcat gtcgggcctg aatatgcagg aaatgatgct ccgttgtcca
     3601 tgctaatcgg ttcactgaat ctttaacatc taacacaatc aatcccacct tcccgtttcg
     3661 atctgactcg attataggcc ggtctggcga aataagcttt caaaagactc gatgatcaac
     3721 ttcagtaacc atccctcgtc aattaagctt ggtcatgccc gcgatcagtt gcttttgcgg
     3781 ccgtttcaga aacctcacgc aaggcttctt taccgctttt atcactgaga ttgatataca
     3841 gatctgtcgc acttgtggtc gtttgcccga gctgatccgc aacctgctgc acatccttgg
     3901 tgaccgtata aatattggtt cccaaagtgt gccgggcctt atgtggtgtt gatggccgac
     3961 cataatcggt tgtataacgc ttgaaaaagg cttcgattgt attttggcga atccgattga
     4021 ttttttggcc gacaactgtc acaaacaggg gagaagtcgg cttttgataa ccaataatag
     4081 ccgctcgctg cgttaagtaa gcctgaacat acggatcaat ccagtctgca aaattgacgc
     4141 gatcctgaaa gttgcctttg cgaacaactt ggaccgtatg ccgatccatg ttcaaatctt
     4201 ccagattcat attcaccaat tcgctgactc gaacccctga gccaaacagt aaggcaatca
     4261 tggccaagtt gcgcactttt gtcgcctcaa aatagcgccg cggcttggct ggcagttgtt
     4321 gcgcataact ttgatccaac cactgtaaaa acttagcatc ttcaccgtcc acaaacagca
     4381 tttcctgtag cttgtggttt cggtaactcg cagtttcagt atgggtttta agttttacct
     4441 tgttccagac attccgatag aaataaggtt cgccatctgc atggggttca ctttcctccg
     4501 tcaaaaaccg ataaagcgcc ttgatcccga ctaagcgcaa agcaacactg cgacgcgtca
     4561 ttcgcttgtt gtggtgcgtc ttggaaggcc gttcaagcaa atacgccata aatgcctggg
     4621 catcacgcaa cgacaaatgt tctaacacgg tcagcgggac ggtttgcggt gaggaagcgg
     4681 ccgtcacacc actgttaatc agccagttca gaaactcttg ataaaaatgt aaatactgat
     4741 agagcgtcga atcggcgatc gggatcgctt tttgactctg ataatagtcc tgaatgtaat
     4801 ccggcagggc aggtagcatt gtatgaatta atttcgaata attttgtgtc gacacagatt
     4861 tcacctcgaa cgtatgtttt cttttagata atgttagtat acgcgaaaac aactgtcctt
     4921 ggcgagggct agtgttgatg aaaaatgaac ggtggtgctg gttcagccat tgttctgcca
     4981 tgtgaagcag aattgaataa agttttagct ttatccaaag gtgagcaaag atgtcagcaa
     5041 acgcctgttg gtcagacaaa ttttagctca cataattctg gtatgaattc ggctattaaa
     5101 tgagttcact tcggtcaatc attcagcaaa cttattttgg ccattggtca ataaaataaa
     5161 tttgctgaat gttgcgtgac cctcaattgt tgttgagtca atttcaaact acacaactca
     5221 aaaaatcatc agtcaactcg aagccggcta actgacgaga atctcacaac atcatgaagc
     5281 ttgaattgat atgcattttt ctggttttgg ctggcatgac attttcaatc aaacaaatgc
     5341 atgcaacaca gcgcaaacgc aacgtcccaa gtcataattg attgccttgg taaaaagttc
     5401 aatagccacc acagccacca ccaacattac gtccgaacca caaatttttg acagccatct
     5461 gaaagagggg acacccagat tcgcagatca agtgccaaag ccaattattt atattctagt
     5521 ttacataata tatattatgc gaagcagtgt ttgaagagac ggcatcgtgc cattctcgca
     5581 atatttacgt tggcgattat ttgattcgca atttcatcca gcacccgata gtcgccgcat
     5641 ttttttaacc gctgcttgca gccaagtctt taaaagcttc tacaatcatt ggaaatcatt
     5701 cgatattttt ttgcttgagt tttttcgtta agtcaacaac tatcaagttg aattcccgaa
     5761 ctcgtctcag aatgcgtctc tcaccatgcc tcaaaaccat ccaaaatgac ccatgacaac
     5821 ttgctgttga ttcgacccgc gaattactac acgnnnnnnn nnnnnnnnnn nnnnnnnnnn
     5881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ccttagaaca attgtgtgca
     5941 attaaagatg aaagttaacc ttcaaacgtg ctctgcattg gcggaacgac ctgctttttg
     6001 cgggaaacaa ccccaggcaa tgccaaacgc gcgtccttgt cgaactgttc gttaaaagca
     6061 ctggcgattt tatcgcggtc agcaccgact gcgaaaccag ttgaattgct gtccaagatg
     6121 tcagtagcaa tcagcaggaa atcgtcgtag cctttcgcct gcgcctcttt ggtcatggca
     6181 ttgatcaatt cgtcctgacg tgcgtaaatg tcgttcagat cgacggtatt gacctgtccg
     6241 atgcgaatag acttgccgcc catggtgaaa ctcttagcat cgccttcgat aatgtccata
     6301 tctgacttgg cggccaaatt agtgcctgcc ttcagcatgg caagaccata tgactgcaaa
     6361 tcaattccgg caatcttcgc catttctggc aaaatcttct tatccttatc ggttgcggtc
     6421 ggcgacttca acaacagcgt gtctgaaatc aaaccagaag ccatcaaacc agccaatgtt
     6481 ggcgaaatct tgaagccata ttcctggaac atctcaaaaa tgacggtatt ggtgctgcca
     6541 accggttctg ctcggtaaaa cagcggcgct gccgtgtgga agttagcgat gcgatgatgg
     6601 tcgacaacag aatcaatcgt cacgtcttcg atatcactga cactttgttg aaattcgttg
     6661 tgatcaacca acatgacatg atccgtctcg ttggctgccg tcttgataac ccgcggtgcc
     6721 tgaaccttga agtgatcaag gacgaactta gtttcatcgt tcggttcgcc taatgctacc
     6781 gcctcaacat ccgtgttgcc tgcctgtttc tgaaattctg cccagctcat ggcactcgta
     6841 atcgcgtcgg tgtccgggtt ctgatgccca aaaatcaaag tcgtcatctt atctgatcgc
     6901 tcctcaactg aataatttac ttatcaagtt taacacggtt ttcactgacc cgcgacaagt
     6961 aatctttttc cttcagataa tcgtcaaagg tctggaagaa gttcgagatc cgcggaatgt
     7021 cagctttctc tttgcgataa acaaaagaaa tctcaaagcg aatggccgga tcaaacgcaa
     7081 tagcataggc cttgatttga tcagcgcgtg cccgaacaaa actggttggt aaggccgtgt
     7141 tgacccctga caagttaacg aattgggtta actgatatgg cgtggtgaaa tgtgcgacca
     7201 cgtgcgggaa atcaaccatt tgattcttgt acgcctcacg cagaagctgt ccaaggaaat
     7261 agtcgtcagg ataagttgcc caaggttcag ctaaagtatc tttgaaatgg attcgcttac
     7321 ggttagccaa ggcgtcatcg tggtgcaaga acagcaattg ttcatcaata attttcttgc
     7381 tggcgtatgg tttccagttc ttaatggttt catctggcag attcatgata gccaaatcaa
     7441 tctggttgtt ttccaatgat tcccaaattt cgtgacgggt catcatccgt agcgttactt
     7501 caacttcagg attcagttga tagtaatgag caatgaacgc aataaaggcg ctatcctcga
     7561 ttgagcttaa taacccaata ttgatttttc cgacggttgc actggttgtt tgttgaattt
     7621 cgtcggttgt ctggttcaag atctcgtaga tctcatgggt tgactttaac atggtctgac
     7681 cagcgtcaga taaatgcagt ttcttcccga cagaataaaa cagcggtgcc cccactgtcc
     7741 gttccaattt cttgatctgc tgtgttaagg ctggctgggt aatgccaagc aattgggcgg
     7801 cttgggtgta gttcatggtt tctgccaatt gcagaaaata agttagtgtc tttgaggaaa
     7861 aaatgcgctc ttgtttcgtt ttcatagggc ggcttccctt tcgtttatta tttaataata
     7921 tcgttcaacc atcatcataa gtggcaatga aaaaaaacgc aacgaatttg ccgcgttttt
     7981 aatcgttacg ttaagttcta gctaaaaatt cagttgctcg caactggttt cggacgccag
     8041 ctttgccatc cggtataatc cttaacgtgc agcagattct ctgcattctt aacgcgatcg
     8101 gcagacggcg gttcgatgcc ttcaagcggg tacgtaatgc caagctcgtg atacttttta
     8161 acgcctaacg tgtgatacgg cagaatctca actttttgga ccacgttttt gtccaatgtc
     8221 gcaatatagt cccctaatcg tttgagataa gggtcaaagt cagtgcgttc cgggaccaga
     8281 acgtggcgaa tccacatgtc atcaccatgc gccgacatat actgcaccat atctaaaata
     8341 ttttcattag gaaaaccggt gagcttttta tgctcggccg aatcgatgtg tttaatatca
     8401 actaatgaga tgtcagtaac agccatcagc ttttcaaact ggccaaacca cggttggtca
     8461 cgcgtgaagg ggccgcctga cgtatcgagg caagtcgaaa ttcccagtgc cttagccttg
     8521 gtgaagagtt cgagaatgaa atcgatttgt accaaactct caccgccact gcacgtaata
     8581 cccccttggt caccccagaa tgctttatag cgctgggcat ccgccaaaat ttgatcggcc
     8641 gtcatttctt caccaacccc aatgttccag gtgtcagggt tgtgacaata ctggcaacgc
     8701 atgcgacacc cttgcataaa gacaacgaag cgaataccag ggccatcgac cgaaccaaaa
     8761 ctttcgaccg agtgaacata ccctttgatc gggccatcat gatcctgacc aacttgttct
     8821 aagatattta atgggctttg tgactgatcg atgagtttca tcttattgcc tccactacaa
     8881 catcatgtgt cgttttcaat tgattttcat ttcattctgc caaaaaacgg caacagcatc
     8941 gttgccgtct tttggcaaaa caggaatggc ttcctgtctt gagttaagct gcttacattt
     9001 cttcgaagaa ggtccgagca atgacatcgt cttgttgttc cttggtcaaa tctgcgaagt
     9061 agacgcagta gccagaaacc cgaacggtca atgttgggta ttcttctggg tgcttctgag
     9121 catcaatcag ggtctccttg ttgaagacgt tgatgttcaa atgcatgccg ctgttttcca
     9181 tatagccgtc aaccatgtga accaaggtat ccttacgagt ttcatcatcg tggcccagtg
     9241 tgttcggagt aaccccaaac gtattactaa tgccgtcagt tgcgtaatga tacggaatct
     9301 tggcggtgga catcaaggat gccaatgcgc cgttcttttc tgcgccgtat gccgggttgg
     9361 cacctggtga gaatggttcg cctttttgac gaccgtttgg tgttgtccct gtattcttac
     9421 cataaaccac gttggaagta atggtcagga cactggtact caacttcgcg ccgcgataca
     9481 gatgatgcgt gttcatcttg ttatagaagg tcttaaccaa ccacttagcg atgtcatcag
     9541 cgcgatcatc gttgttacca taacgtggat agtcatcatt gtcagcaacg aagtcaactg
     9601 caacaccgtt ttcatcgcga attgccttga catgaccata cttgattgca ctgatggaat
     9661 caaccgcgtg tgacaggccg gaaatcccgg ttgcgaaggt ccggttcagt tgggtatcct
     9721 tcaatgccag ctgtgcagct tcataataat acttgtcatg catatagtga atcacattca
     9781 aagcattgac atacgtgtcg gccagccagt ccatcatctt gtcgaactta ttcatgaatt
     9841 ctttgtaatc aatgtaatcg ctggtgatcg gtgcatattc aggccctact tgcgcttcct
     9901 gaatttcatc tttaccaccg ttgatcgcat acagaaccgt cttagctaag ttagcacggg
     9961 caccaaagta ttgaacgcca tcagcaattg gttgtgccga gacacagcaa gcaataccgt
    10021 agtaatcggt accccattca ttgcgcatca ggtcatcatt ttcatattga atggttgaac
    10081 tttggatgga tacttcggtt gcatagcgtt taaagccttc tggcaagcgt tcgctccaaa
    10141 gcaaggtgat gtttggttct ggtgctgcgc ccatgttgtc caaagtcttc aggaaacgga
    10201 aagccgtctt ggtaacgtgg tgacggccat cattgcccat tcctgccaat gacaaggttg
    10261 cccagattgg atcgcctgag aacagtgagt tatattcttc agtccggatg aaacgaacca
    10321 tccgcaattt cataaccaaa tgatcaatca gttcctgtgc ctgttcttcg ttcaatttgc
    10381 ctaagcgcat atcgcgttgg atataagcat caataaccgt atcgatccgg ccaacggaca
    10441 ttgcggcacc gttttgagtc ttaacagcag ccagatagcc aaagtagatc cactgaacag
    10501 cttcttgcgc attagctgcc ggacgcgaga tgtcatagcc atattccttg gccatcttct
    10561 tcatgtcgtt taaggcacga tattgttcat tgatttcttc acgcaatttg attacttcgt
    10621 cagtcatttc gccgtcgccg gtcaagttat aatccttgaa cttctcagcc attaaacgat
    10681 cgatcccgta aacagcgatc cgtgggaaat cagaaacaat ccggccgcgg ccgtatgcgt
    10741 ctggcaagcc agtcacgatc ttgtaatggc gagcctttcg catatcaggg gtataagcat
    10801 caaagacacc ttggttatgg gtcttacgat attcattgaa aatcttgtgt tcttgaggat
    10861 ctgtcttgaa gccataagat tccaatgcat cttcagccat tcgaataccg ccaaatggca
    10921 tgaatgctcg tttgaatggc ttgtcggtct gaacaccaac aatcttttca agatctttgt
    10981 tcaaataacc agggccgtgt gaggtgatcg tagatggaat attgttgtca gcatccaaaa
    11041 caccgccatt tgcacgttct tgcttcttta aatttagaac ctgattgttc aggactgttg
    11101 tcgcttcagt ggggccagca aggaaacttt cgtccccgtc atattggttc aggttatgct
    11161 cgataaaatc gcgcacatta atttcttctt gccagtcgcc gccgttaaag ccttcccaat
    11221 aattaggaac tttggtttcg tcaagctgtt tcatagttgt ttgcctccta aagtggatta
    11281 cagatgtgac agttcttaca aacacagtat aacacgccgc caaatctatg caagcgcttc
    11341 attgcccata taataggcgt tatattgttt tttaagtgtg cttcgtcgct tcttttcgcc
    11401 catgatttcg gcattttgtt aaattgtgca caactggtct gtcctataat aatcaaaaac
    11461 gccaccatct gtattagtac agacggcggt gtcaatgatc accatttatt cgacttgatc
    11521 tgctggttct tctttggttt gaacaaaaac tggcttgcca aggacatcag tgtcaatgac
    11581 aaacgaacca ttcgaatagc ggtcacctgc tggatgctgt gccggattaa gggtcgttac
    11641 cttacccgta tcggtcaaaa cattcaggcg ggtagcgtca tcgactgaca tcatcgcgac
    11701 aatccgatgc ggatcacgct taagctcacg caagaccagt aaaccacgac gggcacgact
    11761 catttccccg acttcgctta aggccatctt tttgaaggcg ccacgttggg tcaaaatacc
    11821 gaccttagcc gtagttggat ccttcactag aatgaaattg acaacctcat cgtctggctt
    11881 tagatccata cttttaacgc cggttgcccg ggcaccgaca gttgacacat cgcttaacgg
    11941 gaatgtcagt ccgtaagcgt ggcggctgac cacaaagaca tcctgttgct gatcagtcgt
    12001 gaagtatgca ttggtgacaa tcgcggctgg gtctttcagc ttcatcgcca tcatcggctt
    12061 actcttgtac gtccgttgcg gctgcaaatc acttaaggca gtttgtttga tgtacccgtc
    12121 acttgaccct aacacaaaac tgccagcgcc atcgagttga tcaaaagcaa acactgccaa
    12181 gactttttcg tcagtgccaa ggccaactgt ttggcttaag tgttcgccgg tgtctttcca
    12241 acgcgcatca ctaatttcat gcactggtcg ataaatgaca tttccggcat ttgtcacgat
    12301 gtaaagatgc tgcaacgtac tcagttcgcc agtgaaaatg gcaagatcat tggccttcaa
    12361 accattgtcg gccggatcaa ccgcctgata actgcgcagt gaactgcgtt taacgtaccc
    12421 atcacgagaa acctgcacca tgacggtttc atcagccacc gtcaccgttg tcgccacttc
    12481 aagtgtttca attttggctt gaatgctgct gcgacgatca tccccgtact ccttggcaat
    12541 ccgcttcaac tcgccttcaa tcacccgatc gcgggcagcg gggcgggcca aaatatcttg
    12601 atactcggcg attgctttcg ccaattgtgc tgcttctttc tgtaaagccg tgatatcggt
    12661 attggtcaat cgatacagct gcaaggaaac aatcgcttcc gcctgagctt ccgaaaaatc
    12721 aaacttcttg actaagttac gcttagcatc ccctttatcc ttggaagcac gaatcgcggc
    12781 gatgacctga tccaaaatcg atagcatttt gatcaagcct tcgacaatgt gctgtcgagc
    12841 agcggccttg ttgaggtcaa aacgcgttcg ccgagtgacc acatcgcgtc gatgctcgac
    12901 gtatgcttcc aacatggcct taagtcctag caacttcggc tgcatgtcgg caatagcgac
    12961 catgttaaag ttgtatgcaa tttgtagatc ggtattttta aataaatagt ttaagatgcc
    13021 atgtgcatcg gcttcttttt ttaattcgat gacaacgcta agcccaaaac ggtcgctttc
    13081 gtcacggact tcggcgatac cgtccacttt tttgttgatg cgtaattcat cgattttttt
    13141 aatcatctgc gctttattga catcatacgg gatctcagtg accacgatct tctcacgacc
    13201 gccacgaatg gtttcgatgt gtgtccgaga acgaaccacg attttaccgc ggccggtttc
    13261 gtaagcttgc ttgatgccat caagcccttg aataatccca cctgttggaa aatcgggacc
    13321 cttgacgtat tgcattaaag tatctaaatc agcagtggga tgcttcagca agtataagac
    13381 ggcggcaata acttcccgca gattgtgcgg cggaatttcg gttgcataac cggcagaaat
    13441 accggtggca ccgttcacca gcaaatttgg aaacccagct ggcagcacag tcggttcctg
    13501 tgccgtgtca tcaaagttca acaccatatc gacggtttcc ttatcgatgt cggccagcat
    13561 ttccttgctg attttgctta aacgcgcttc cgtgtatcgc attgcagctg gcggatcacc
    13621 atccatggaa ccgttattcc cgtgcatctg aatcagtggg gcccgtaact tccaatcctg
    13681 gcttagccga accatcgctt cataaatgga gctgtcgccg tggggatgat aattacccat
    13741 gacattcccg acacttttag ccgacttgcg gaagccctta tcatacgtat tgccatcttg
    13801 gttcatcgca aataaaatgc gacgctgaac cggtttgagg ccgtcacgca catcaggcag
    13861 cgcccgttct tgaataatgt atttcgagta ccggccaaac cggtcgccca tgacctcttc
    13921 taaggtcagt tcttgaatct gattggccaa tggcttttac tttcctttct tgtccagttg
    13981 tttgacgatt tgcttggcac caaactgtaa tttttcgtga ttagcagtcg gggtttccaa
    14041 aatactgccg tcgtcatcca tatcaaactt gacgttatgc tcaatccatt cacgacgcgg
    14101 cacccatcaa agtggtcacg cgtcgttccg ccagctgagc atcgtcaatc cgaacccgga
    14161 tcaaagtccg cgtctcagga ttcatagtcg tttcccaaag ctggtcggca ttcatttccc
    14221 caagtccttt aaatcgggtc aatgtgtaac ccttgcccat ggccttggtc tctttggcca
    14281 actcttcatc ggtccaagca taactgatct tggttttagc accagcgcct ttttgcagcc
    14341 gatacaatgg tggcaaagca atgtaaattc ggcctgcgtc aatc
//
