Select genomic region:
Overview
12.1
12.2
12.3
12.4
13.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaBIMOEBCE_12 (original name was: gnl|Prokka|BIMOEBCE_12)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | RiPP-like | 417,540 | 428,475 |
Region 12.2 | RiPP-like | 1,608,621 | 1,623,495 |
Region 12.3 | RiPP-like | 1,644,310 | 1,659,792 | gassericin T | RiPP | 44%
Region 12.4 | LAP | 1,907,168 | 1,930,280 | listeriolysin S | RiPP:LAP | 25%

gnlProkkaBIMOEBCE_13 (original name was: gnl|Prokka|BIMOEBCE_13)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 13.1 | lanthipeptide-class-i | 178,329 | 202,247 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | RiPP-like | 417,540 | 428,475 |
Region 12.2 | RiPP-like | 1,608,621 | 1,623,495 |
Region 12.3 | RiPP-like | 1,644,310 | 1,659,792 | gassericin T | RiPP | 44%
Region 12.4 | LAP | 1,907,168 | 1,930,280 | listeriolysin S | RiPP:LAP | 25%
Region 13.1 | lanthipeptide-class-i | 178,329 | 202,247 |

No secondary metabolite regions were found in these records:
  gnlProkkaBIMOEBCE_1 (original name was: gnl|Prokka|BIMOEBCE_1)
  gnlProkkaBIMOEBCE_2 (original name was: gnl|Prokka|BIMOEBCE_2)
  gnlProkkaBIMOEBCE_3 (original name was: gnl|Prokka|BIMOEBCE_3)
  gnlProkkaBIMOEBCE_4 (original name was: gnl|Prokka|BIMOEBCE_4)
  gnlProkkaBIMOEBCE_5 (original name was: gnl|Prokka|BIMOEBCE_5)
  gnlProkkaBIMOEBCE_6 (original name was: gnl|Prokka|BIMOEBCE_6)
  gnlProkkaBIMOEBCE_7 (original name was: gnl|Prokka|BIMOEBCE_7)
  gnlProkkaBIMOEBCE_8 (original name was: gnl|Prokka|BIMOEBCE_8)
  gnlProkkaBIMOEBCE_9 (original name was: gnl|Prokka|BIMOEBCE_9)
  gnlProkkaBIMOEBCE_10 (original name was: gnl|Prokka|BIMOEBCE_10)
  gnlProkkaBIMOEBCE_11 (original name was: gnl|Prokka|BIMOEBCE_11)
  gnlProkkaBIMOEBCE_14 (original name was: gnl|Prokka|BIMOEBCE_14)
  gnlProkkaBIMOEBCE_15 (original name was: gnl|Prokka|BIMOEBCE_15)

Compact view
gnlProkkaBIMOEBCE_12 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 417,540 - 428,475 nt. (total: 10,936 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaBIMOEBCE_12 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,608,621 - 1,623,495 nt. (total: 14,875 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaBIMOEBCE_12 - Region 3 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,644,310 - 1,659,792 nt. (total: 15,483 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaBIMOEBCE_12 - Region 4 - LAP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,907,168 - 1,930,280 nt. (total: 23,113 nt) Show pHMM detection rules used
LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
gnlProkkaBIMOEBCE_13 - Region 1 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 178,329 - 202,247 nt. (total: 23,919 nt) Show pHMM detection rules used
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg13_183

ctg13_184
Leader:
MTESALLDLKIDESAVNAFDAEGY
Core:
A K S Y S A Y S S C S C V N P P C P I A T M D
Core with dehydrations:
A K Dha Y Dha A Y Dha Dha Cys Dha Cys V N P P Cys P I A Dhb M D

#### MIBiG 3.1 matches for ctg13_184

13.0% BGC0000563 (AEA03263.1): Lanthipeptide: venezuelin
8
S S C S C V N
14
++C C V
1
A T C E C V G
7

#### antiSMASH-DB 4.0 matches for ctg13_184

100.0% NZ_CP017706.1 and 3 others:
NZ_CP025200.1 Lanthipeptides: CXB72_RS10430_lanthipeptide NZ_CP083726.1 Lanthipeptides: LA162_RS02790_lanthipeptide NZ_CP083726.1 Lanthipeptides: LA162_RS02790_lanthipeptide
Lanthipeptides: LA20531_RS11120_lanthipeptide
1
A K S Y S A Y S S C S C V N P P C P I A T M D
23
A K S Y S A Y S S C S C V N P P C P I A T M D
1
A K S Y S A Y S S C S C V N P P C P I A T M D
23
26.1% NZ_KL997439.1 and 1 other:
NZ_KL997439.1 Lanthipeptides: allorf_330534_330731_lanthipeptide
Lanthipeptides: allorf_330534_330731_lanthipeptide
8
S S C S C V N P P
16
S S S C++P P
7
S S A S C I S P P
15

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg13_184 - Class I
  Cleavage pHMM score: -7.20
  RODEO score: 18
  Monoisotopic mass: 2286.0 Da
  Molecular weight: 2287.6 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2305.6 Da N = 1
    2323.6 Da N = 2
    2341.6 Da N = 3