LOCUS       gnlProkkaBIMOEBCE_12   14875 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BIMOEBCE_12.
ACCESSION   gnlProkkaBIMOEBCE_12
VERSION     gnlProkkaBIMOEBCE_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:26:32
            Original ID  :: gnl|Prokka|BIMOEBCE_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1608620
            Orig. end    :: 1623495
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14875
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:9875]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9875
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14875
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14875
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(318..1556)
                     /locus_tag="ctg12_1655"
                     /transl_table=11
                     /translation="MDQNPKRREDYRARRSSLNLHRNRAFAADAPALKPGNFLARLVGV
                     VALLAVCFGVAWAAHMYFTVHSVIDSKNGGNTATSAKIVNRQPISILVLGVDQGIEGRH
                     DRGNSDTMILATANPQKNSATMTSIPRDTLADIKGDPGDKYFMFRVNSAYEIGGHESSM
                     KTVSSMLNVPINYYLEVNMKALKSLVNAVGGVDVNVPFDFSYDWCDFHKGKQHLNGRHA
                     VAYVRMRKEDPRGDYGRQMRQRQVIEAIAHKAMSVNTLSNYRKLVDVFNKYVKTNLTFN
                     DMLSLALNYRGCMKNMKSSYIQGHDAWIDGASIQVASTKELQKTSDRIRKNLNLSTQTL
                     NNEETRQNELNDQNNHIKWDDPQAFTNYQIYDQNQDKPASGSNSGYGEGTGTGSSSSSS
                     SSSSSSSGWHFHW"
     CDS             1724..3520
                     /locus_tag="ctg12_1656"
                     /transl_table=11
                     /translation="MAIPNRNEVPEELKWDLTRIFKNDEEWEQAYAAAQEKIDQLGELK
                     GTLAKSGKDLYEGLTKILAVKREVENIYVYATMSSDVDTANSHYLGYVSRVQSLANQFE
                     AATSFINPEILSIPSDKLAEFKQAEPRLKNYAHYLEMITNKRPHTLPAEQEKLIADAGD
                     ALGVSENTFNVLTNSDMEYGYVQDDDGNMEQLSDGLYSLLIQSQNRDVRKGAFDTLYAT
                     YSQFQNSLASTLSGVVKKHNYNAKAHKYDSARQAALAENGVPEAVYDTLIQEVDSHLDL
                     LHRYVALRKKILGLKDLQMWDMYVPLTGKPSLSYNFEEAKEVAKKALKPLGEDYLKHVD
                     YIFNNRVIDPIESKNKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYT
                     RNTQPYVYGDYPIFVAEIASTTNENILTEYFLDHITDPKTRAFILNYYLDSFKGTLFRQ
                     TQFAVFEQFLHEADANGEPLTADTLDDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYY
                     NFYVYQYATGFAAATALANKVVHGTPAERDAYLGFLKAGSSDYPTEIMKRAGVDMTKPD
                     YLEDAFKTFEKRLNEFESLIEK"
     CDS             complement(3601..3873)
                     /locus_tag="ctg12_1657"
                     /transl_table=11
                     /translation="MENAKELKSLLVGVKQKVVEDSAAVELINHALSNLEQGVNIEKVV
                     FDLKRDLNNYSLSHNFKLPQPLTELQLKLNENSNKWRDAGLTGSI"
     CDS             complement(3951..4748)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_1658"
                     /sec_met_domain="Abi (E-value: 5.7e-16, bitscore: 56.0,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKYYLALADEVEFSNKAEVNKTIRNLFILAIILLIGSFVLPHL
                     IVGNMITKWLIVIIFIVAFAYVAEHFILTTKTFNQRLKLQGISKVMMIIYCVFLALILF
                     GALKDKILLFKLPLYQIMVAALAAILPAICEEFLFRGILFNTFLLVFRKEKYDILWTSI
                     VCSILFGLYHLNNLTSQSLISTVGQVIITLGMGLFLSYLRVWSNGLIWCMVVHFLQDFS
                     PKILSTDYGTSKIKLTVLVATLIVILMLICIYTINRRFLELSN"
     CDS             complement(5001..5141)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_1659"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.7e-09,
                     bitscore: 33.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFQKLSTAELQNIVGGRGKSSWWRNVQRGVSQFMSGLRDGLAG
                     K"
     CDS             complement(5185..5358)
                     /locus_tag="ctg12_1660"
                     /transl_table=11
                     /translation="MKDYLMLLVNISFLVTWFYTPKTQIGTWVAAIVAVVALIVDTVDI
                     INFIFKSRKRNE"
     CDS             complement(5703..5882)
                     /locus_tag="ctg12_1661"
                     /transl_table=11
                     /translation="MESTVNFEKLNSNKLVSVVGGSHSRNYYNGRGTGRNIRAAGTVAN
                     VIWTGAKIISHFLG"
     CDS             complement(6090..6728)
                     /locus_tag="ctg12_1662"
                     /transl_table=11
                     /translation="MSDQDLESSKFYSYKFRNFSTMIILPAFILVILLFLGSFFAVHEN
                     VVNSMGVITPDHVLSLQNRAYREGQKLSKGINLTLANGKKRVLKDNAIVHLDNKDSVAM
                     PDIKNRRKLRVVTYVPSSEVAVLNKGQQVRFQIENKQGMSEILNGKIISIGTYPVQQKG
                     MSMFEVETMLKTTKSERKFLRYGMQGKVSIITGKASYFNYIKSKLLNSK"
     CDS             complement(6896..7753)
                     /locus_tag="ctg12_1663"
                     /transl_table=11
                     /translation="MNYLKLNRFSHHLQVSFSRLNVICRSLYNLYAPDKLTHRKNIDQT
                     KLSDSSILAMLIWQTEIGIESQRRFCKFFVGLSHSRFNRRAKMLLPLIRCIRQAWNQEV
                     KVAGEFLIIDSFPVPVCQPVRNYRVKIFRDIADIGYKATKKVYYYGFKVHALVSDEGYL
                     LDYAVTKASVHDAKETVELMINAHPINHYLLGDEGYLGKDLAAELKGMGYVLWTPYRKN
                     MKGAKKHNNHQLMAIRRTIESDFSLLSYYNAENNRARSLAGFQQRLEIAILAYNMAYCL
                     ERFN"
     CDS             complement(7833..9875)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 279.1; E-value:
                     1.3e-84)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_1664"
                     /sec_met_domain="Peptidase_C39 (E-value: 9.1e-44, bitscore:
                     145.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 7.7e-303, bitscore:
                     1003.5, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMGMLTYKSIYVPQIDETDCGAACLAMILKNYHSQVSIAHLRHIA
                     KTNTEGTTALGLVKTAEKFNMDVQAVKADMSLFNMKDIQYPFIVHVIKDGGLLHYYVVL
                     KSTKRKIIVADPDPTSGIKKMSKKAFEKEWTGITLFMVPKADFKPVKEKKNNLLSLFPY
                     MFKQKKLVRNIILAALLMTLISICSSYFVQGLIDTYIPNGTFTTLSVLAIGLLIAYVFN
                     SIFSYGQQFLLNVLGQRLSIDLNLQYIKHIFELPMEFFTTRKTGEITSRFSDASRIIDA
                     LASTVISLFLDLSIVILMGIILAVQNMTLFLITLASLPLYAIVILGFSKRFERLNNDQM
                     ESNAVVSSSIIEDIQGIETIKALNSEQVRYRKIDSQFVDYLKKAFKYSKTEAFQTALKT
                     FIRLSLNVIILWVGASVVMHNQMSIGELMAFNALLSYFIDPLQNIINLQPTLQAANVAQ
                     NRLNEVYLVQSEFKGKTSVNDSHDLNGDINFSHVDYRYGYGEDVLKDINLTIKDNEKLT
                     IVGMSGSGKSTMVKLLVDFFSPTKGKVTFNGHSTRSINKHVLRSYVNYVPQTPYIFAGT
                     IKENLLLGSRKNITEKEIEEACQIAEIKNDIEKLPLGFNTQLDENAKILSGGQKQRLTI
                     ARALLSPAKVLIFDEATSGLDTITEKKVVDNLIRLKNKTVTRGAS"
     CDS             complement(9853..10677)
                     /locus_tag="ctg12_1665"
                     /transl_table=11
                     /translation="MQYPVFICDDDQNQIEQTKKILGAAEMILSDDEEIEFSIASSTDY
                     MGAIDYLKKHKLDGGIYFLDVELGGDTEEDTGFDLAALIKKRDERAQIIFVTSHADLSL
                     ITFRRRLGPIDYIVKTSDLDKFRQMMVKTVEVAIYNLHKFNYMKKMTFSYKIGRQTRNV
                     NIDDIIYISTTITPHKLLMILTTGEMQLLGSINQYAKENPMLEKINQSCLVNPKNIESI
                     DLKQHRVSFVNGDVEDFSRSSVKMMKDFLARYNYKTEKLAKQKEINDGHVNV"
     CDS             complement(10681..12087)
                     /locus_tag="ctg12_1666"
                     /transl_table=11
                     /translation="MFFQALFSPVIDLYIFYRLSGWKFKREDYAFSIVFIGTCVLAGSV
                     VQIDDFLVDIIQAFLIFLFSYLVKKEKKVKFIFGAILFFELLDLLITISAEIILLIFDI
                     SSSSMTFVFLLVEFVIIVIIQKYYLKIRKLLNDRNSSIFIGLIFYVYLSSSIVYFLALK
                     STHMTIVFEVSLSLLVLQIVFSVITYIAIIKVQKGLLTKQEQKEQKFQLELANADRKAK
                     EAENKELILKQQQLSSEMEQLQEYSNYLDKNEDDLHRFKHDYQNILNGLKVSAQEGNTA
                     EVVKILDQYTETQFNKKALRKYNGVNHIHEKNLKSIAIAKLSKLYSLGLDYSFDCEHDI
                     SRIPDSVNILDLVRIIGITFDNAAEESQALIKETGNSNSARIDAMYYQENGDFEFEIRN
                     RVRKSGVATDKISQKNYTTKKHHMGLGLANVKEITHKYEDSMIVNYYVDDGWFTFDLTI
                     LPDSESGTEK"
     CDS             complement(12173..13351)
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 407.8; E-value: 5.8e-124)"
                     /gene_kind="other"
                     /locus_tag="ctg12_1667"
                     /transl_table=11
                     /translation="MNDFTKDFAQALFNPDKINDLLRKELQQAVNNLLEAELTAFLGYD
                     PYARNGWNTGNSRNGAYFRKVDTQFGPIEVQVPRDRNGQFHQHTLPGYKQHSDILESMI
                     IKLYSKGVTTREIADLIEKMYGSHYSPAQVSNISKQMIPKVEAYHKRKLSDKFFCVYLD
                     ATYLPLRRETFEREAVYIAIGIKPNGHKEVIDYCIAPSENIEVWTDMLQNMKSRGLKQV
                     ELFLSDGVVGMKTALARTYPKAHFQRCLVHVMRNICAKVRVDDREKIMNEFKQVHQQTN
                     KEEATAVLHDFYTKWGKVYSHVIRSLKDIEPDLLVFYNYPKQIRASIYSTNMIESFNNV
                     IKRKAKPKAEFPTEQSLDVFIGIQAMSYNDRYFNRIHKGFGQVQDTLESYFD"
     CDS             complement(13468..13617)
                     /locus_tag="ctg12_1668"
                     /transl_table=11
                     /translation="MKKLNEKELVEVKGGFADPTVSFFALNDITINKKHRNHFNWKKIF
                     ETVK"
     CDS             complement(13737..13859)
                     /locus_tag="ctg12_1669"
                     /transl_table=11
                     /translation="MRKLSTSILEKIVGGRSKIRRHFFKSNSRGWGNGSGGGTF"
     CDS             complement(13992..14174)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 56.2; E-value: 9.2e-17)"
                     /gene_kind="other"
                     /locus_tag="ctg12_1670"
                     /transl_table=11
                     /translation="MKAARVGKDLTQEDLAQQIDVSRQTISAIEKGNYNPSINLCIKIC
                     QALDKTLDDLFWPEG"
     CDS             complement(14186..14671)
                     /locus_tag="ctg12_1671"
                     /transl_table=11
                     /translation="MSKFEILKLMAFASLFAVMTFILVVVFVGNRRAAKYDERQELIRG
                     RGDRYGFLVLIVGEVISALFMQTDFYTKHGIAVNFAIIMLSLTVMSVYDIVHGAYFAFN
                     EEHVKANSWLYVVLGICLILGYIDDFNSALNIMGIYWLIIGVVSLFQLHRDKESDKD"
ORIGIN
        1 agcgatcaaa atggccagag atatcccaag ccgtgccgca caaaccacca agtgctaagc
       61 taacaataaa taaaacagga tagtgactct tgggcatatt attagtaaca ttctcccagc
      121 caatacctaa ggctgctaaa cccattgcaa taaagagtac atcttcaaat cgtttattga
      181 ttcctttttt caaaaaacag ccaatagttg ttcctactag taaggctaac gtatttacaa
      241 ttgttccaat catccttctc acctcttaag attattttac cgcagaaaaa aagtatcctt
      301 gtcggatact ctttcattta ccagtgaaaa tgccaaccgc tacttgaact ggatgatgaa
      361 cttgaactag acgagctgcc tgtccctgtt ccttcaccat aaccagaatt agaaccgctg
      421 gctggcttat cctgattttg atcataaatc tgatagtttg taaaagcctg cggatcatcc
      481 cacttaatgt gattgttctg atcattcaac tcattctgcc gtgtttcctc gttattaagc
      541 gtttgggtcg ataaattcaa attcttgcga attctatcag aagtcttttg caattcctta
      601 gttgaagcaa cttgaattga ggctccatca atccaggcat catgaccttg aatatagcta
      661 ctcttcatat ttttcataca gccacgataa ttcaacgcca agcttaacat atcgttgaag
      721 gtcaaattag ttttcacata cttattaaag acatcaacta gcttgcggta attgctgagc
      781 gtattaactg acatggcctt gtgggcaatt gcctcaatta cttgacgctg gcgcatctga
      841 cgaccatagt caccacgtgg atcttctttt ctcatccgca cataagctac agcatgccgg
      901 ccatttaagt gctgtttacc cttgtggaaa tcacaccagt catatgaaaa gtcaaacggc
      961 acattcacat caacaccgcc taccgcatta accaagctct tcaatgcctt catatttact
     1021 tcaagataat aattgattgg cacattaagc atggacgaga ccgtcttcat acttgattca
     1081 tgtccgccaa tttcataagc agagttcacc cggaacataa agtatttgtc acctggatcg
     1141 cctttaatat ctgctaaggt gtcacgtgga attgaggtca tcgttgccga gtttttttgc
     1201 ggattagccg tggctaaaat catggtatcc gaattacctc gatcatgccg tccttcaatt
     1261 ccttggtcaa ctcccaacac taaaattgaa attggctgtc gattaacaat tttagcggaa
     1321 gtagcagtat taccgccatt cttgctatca atcacactgt ggacagtaaa gtacatatgt
     1381 gcggcccaag ctacgccaaa gcaaacagct aataaagcta ccacgcccac tagccgagcc
     1441 agaaagttcc ctggcttcag cgctggcgcg tctgccgcaa atgcacgatt acggtgaaga
     1501 ttaagcgatg aacgacgagc acgataatct tctcttcgtt ttggattttg gtccattctt
     1561 ttgatctttt cccttcgaaa ttaatacaag ttagtttatt tgtatcactt ttcgtctcta
     1621 gataaaataa aaataccgat aattaataat aacttgtttt tttgcgaaag atagcataac
     1681 aggctaagat gtatacaaat tgaaataatt atggaggaaa aatatggcga taccaaacag
     1741 aaatgaagtc ccagaagaac ttaagtggga cttgacccga atttttaaaa atgatgaaga
     1801 atgggaacag gcctatgcag cggcccaaga aaaaatcgac caacttggtg aattaaaagg
     1861 tacattagca aaatctggca aagatttgta cgaaggctta actaagattc tggccgttaa
     1921 gcgcgaggtg gaaaatattt atgtttatgc caccatgtct agcgatgtgg atactgccaa
     1981 ttcacattat ttaggctatg tcagccgggt gcaaagctta gctaaccaat tcgaagccgc
     2041 tactagtttt attaacccag aaatcttgag catccctagt gataaactag ctgaatttaa
     2101 gcaagctgag ccaagactaa agaattatgc tcactacttg gaaatgatta ctaataagcg
     2161 acctcatacc ctgccagctg aacaagaaaa gttaatcgct gatgctggag atgctttagg
     2221 cgtttccgaa aatactttta acgttttaac taactctgac atggaatacg gctacgtcca
     2281 agatgacgat ggcaacatgg aacaactatc tgacggtttg tactcattat taattcaatc
     2341 gcaaaaccgt gacgtcagaa aaggtgcctt cgacactctc tatgctacgt acagccaatt
     2401 ccagaattcg ctggcttcaa ccttgtccgg cgtagtgaaa aaacacaact ataacgctaa
     2461 agcgcacaaa tatgactctg cccgtcaagc agcactggct gaaaacggcg tacctgaagc
     2521 agtttacgat actttaattc aagaagttga ttctcacctt gacctgctcc atcgttacgt
     2581 tgccttgcgc aagaaaattt taggcttaaa agatttgcaa atgtgggaca tgtacgtgcc
     2641 gctaactggg aagccttctc tttcttataa ctttgaagaa gctaaggaag ttgctaaaaa
     2701 ggcattgaag cctttgggcg aagactactt gaagcatgtt gactatattt ttaataatcg
     2761 tgtcatcgac ccaatagaat ctaaaaacaa ggtaactggt gcctactccg gtggtgctta
     2821 tgataccgat ccttatgagt tgctcaactg ggaagataac atcgattcac tttatacttt
     2881 agtccacgaa actggtcact ccgttcactc ctggtacact cgcaatactc aaccttacgt
     2941 ttacggcgac tatccaatct ttgtggctga aattgcttca actactaatg aaaatatttt
     3001 gaccgaatat ttcttagacc acattaccga tcctaagacg cgggccttta tcttaaatta
     3061 ctaccttgat tcatttaaag gcactttatt ccgtcaaact caatttgccg tgtttgaaca
     3121 attcttgcac gaagccgatg ctaatggaga accactgacc gctgacactt tagacgacgt
     3181 ttacggtcaa attaatcagc attattacgg cgatagcgtt gaaccaggcg gcgatattgc
     3241 ccttgaatgg tcacgaattc cacacttcta ctacaatttc tatgtgtacc aatatgcgac
     3301 tggctttgcg gctgcaacag cattagcaaa caaggtggtt catggaacgc ctgctgagag
     3361 ggatgcctac cttggctttc ttaaagctgg ttcaagtgat tacccaactg agatcatgaa
     3421 gcgtgctggc gtagacatga ctaagcctga ctacttagaa gatgccttca agacttttga
     3481 aaaacggttg aacgaatttg aaagcttgat tgagaaataa ataatcgcgc tcatataaaa
     3541 aatcgatatc atttcgtaag atttgatatc gatttttttg ttgatgatac ttatttttat
     3601 ttaaattgaa cctgttagac ctgcatcccg ccatttattg gaattttcgt ttaactttag
     3661 ctgtaattca gttaatggtt gaggcagctt gaaattatgt gacaatgaat aattattcag
     3721 atcacgtttc aagtcaaaga ctaccttttc aatattaact ccctgctcca aattacttaa
     3781 agcgtgattg attagctcta ctgctgcgct atcttcgaca accttttgtt ttacaccgac
     3841 tagaagtgat ttcaactctt ttgcgttttc catatcgttc tcctatcacg ctcatataaa
     3901 aataatcggt atcattttag catatttgat accgattatt tttatcgatt ttaattactt
     3961 aattccaaaa atctacgatt aattgtataa atacaaatta acattaaaat tacaatcagt
     4021 gttgccacca ataccgtcaa tttaatttta gaagtaccat aatctgtgct caatatctta
     4081 ggtgaaaagt cctgtaaaaa gtgtactacc atacaccaaa ttaatccatt ggaccacact
     4141 cttagataac taaggaataa ccccataccc aatgtaataa tcacttgacc aacagttgaa
     4201 attaatgatt gactagttaa attatttaaa tgatataagc cgaacagaat tgaacataca
     4261 atagatgtcc ataagatatc atatttttct ttacgaaaaa ctagcaagaa agtattaaat
     4321 aaaatccctc taaataaaaa ttcctcacag attgcgggca atatcgcagc taaagccgct
     4381 accattattt gatacagagg caacttaaat aataatattt tatcttttaa tgctccaaaa
     4441 agtattaagg ccaaaaagac acagtagatg atcatcatta cttttgatat tccttgcaat
     4501 tttagccttt gattaaaagt cttagtcgtt aaaataaaat gctcggctac atatgcaaaa
     4561 gcgactataa agatgattac aatcaaccac ttggttatca tgttgcctac aattaaatgt
     4621 ggcaacacaa atgaacctat taaaagaatg attgcaagta taaatagatt tctgattgtt
     4681 ttattgactt cagccttatt actaaattct acttcatcgg ctaatgccaa gtaatattta
     4741 ttattcaatg tttcacccta atacttttat atgaaataat aaggctaata aattctaatt
     4801 aaatttatta gccttattac ttataacttt caaacgttcc aaatactaat aggtctcatc
     4861 gaactattca gcatttgact aacatttcgt agagttctcc caaaattgcg accagcatag
     4921 taattacgag agtgtccttt accacctata gtatttttta attgatctaa cgtcaattct
     4981 tccattttaa tactttcttt ttatttacct gctaagccat cacgaaggcc tgacataaac
     5041 tgacttacgc ccctttgtac atttctccac caagagcttt taccacgacc acctacaata
     5101 ttttgtaatt cagcagtact tagtttttga aaattattca tttctatacc tccaatacta
     5161 attagcaaat ttctttaccg ataattattc atttcgtttt cttgacttga aaataaagtt
     5221 aataatgtca actgtatcta caatcaatgc aacaactgct acaattgctg ctacccaagt
     5281 accaatttga gtcttgggag tataaaacca agtcacaaga aaagaaatat ttactaataa
     5341 cattaaatag tctttcattt ttctcctacc aagttgatat cgattaacct ttcatcttat
     5401 tactttaaaa gctaccttgt ttacgtcagc ttaatcagtt tcctagttct aaatatatag
     5461 tccaagaata acgcccctga aatttgactt ataatcgaaa tacgcgagga tgcgttcact
     5521 aataaaatgt atcaaatcaa acaataacat gtttaaagga tattatattg ataaaaaatt
     5581 aaagcaacga tatccaataa aacacttcta aacaaaagtt ttttatagag aagagcagtt
     5641 aaatttctca aaactactaa aataaagaat attatcttat acttttgcct ataacttaaa
     5701 ttttatccca aaaagtggct gataatctta gctccagtcc aaataacatt tgcaaccgtt
     5761 cctgcagccc taatatttct accagtacca cgaccattgt agtagtttcg agagtgacta
     5821 cctcctacaa cacttactaa tttgtttgaa tttaactttt caaaattaac agtactttcc
     5881 attttgatac ctccgataaa tctttaagcc tgcctcactt agtacctcta agtaccttat
     5941 caacttacat atataacttt accagaatag tggtattttc tatgacattg tcataagtta
     6001 gcaacatcca catcatattc tgctaaagta cataatttga tccaaaactg cctactatat
     6061 gagtttcaat catcgacatc tcactaattt tacttagaat ttagcaattt agacttaata
     6121 taattaaagt aactagcttt tcctgtaata attgacactt taccttgcat cccataccgc
     6181 aaaaactttc tttctgactt ggtagtctta agcatagtct ctacttcaaa catgctcatc
     6241 cctttttgtt ggacaggata agtacctata ctaataattt tcccattaag tatctcagac
     6301 attccttgct tattctcaat ctgaaatctc acttgttgtc ctttattaag tacagcaact
     6361 tcagaactag ggacatatgt tactactctc agttttctcc tattttttat atctggcata
     6421 gcaacactat ctttgttatc caaatggaca atagcattat cttttaatac tcttttttta
     6481 ccattagcta aggtgagatt aatccccttt gacagttttt gcccctctct atatgctcta
     6541 ttctgcaaag ataatacatg atctggcgtg ataacaccca tactattaac cacattttca
     6601 tgtacagcaa agaaagatcc caaaaataat agaattacta aaataaaggc tggcaaaatt
     6661 atcatcgtgg aaaagttgcg aaacttatag gaatagaact tactactttc caaatcttga
     6721 tcactcatta atatcaccta acttttcacc aaattgtaat aatagccacg ctttttcatt
     6781 aattcgttat gattaccttg ttctacaact tgaccttgat tcaataccac aatattgtca
     6841 gttctctcag caatagctaa acgatgcgca ataaatataa cagttacgcg tggtgctagt
     6901 taaatcgttc taggcaatat gccatattat aagctaaaat ggctatttct agccgctgct
     6961 gaaagccagc taagctcctt gctcggttat tttcagcgtt atagtaactg agcaaagaaa
     7021 agtcgctttc aattgttctt ctaattgcca tcagttgatg attattatgt tttttagcac
     7081 ctttcatgtt ttttcgatat ggtgtccaaa ggacatagcc catacctttt aactcggcag
     7141 ctaagtcttt tcctaagtag ccttcatcgc ctaaaagata atggttaatt ggatgagcat
     7201 taatcatcaa ttctactgtt tctttggcat catgcactga tgctttagtg actgcgtagt
     7261 caagcaaata gccttcatcg cttactagcg cgtgcacctt gaaaccataa taatagactt
     7321 tcttggttgc tttatagcca atatcggcta tgtcacggaa gatcttaaca cgataattac
     7381 gaacaggctg acaaactgga acaggaaaac tgtcaataat taaaaattct ccagcaacct
     7441 ttacctcttg attccaagct tgacggatgc agcgaattaa aggcaaaagc atcttggctc
     7501 gacgattaaa gcgagaatga gataagccaa caaaaaattt acagaatctt ctttgggatt
     7561 caattccaat ttcagtttgc caaatgagca tcgctaagat ggagctgtcg gaaagctttg
     7621 tttgatcaat gttttttcga tgcgtaagct tatcaggcgc ataaagatta tatagtgaac
     7681 gacaaattac atttaaacga ctaaaactaa cttgtaaatg gtgagagaaa cgattaagct
     7741 tgaggtagtt caattagatc agactctttt ctatttaatt tacttacaac ttgagtctaa
     7801 tccgattgga cttttttatt aactaaaacg atttaactag caccacgcgt aacagtttta
     7861 ttctttaacc taattaaatt atcaaccact tttttctcag taattgtatc aagcccactt
     7921 gttgcttcat caaaaatcaa taccttagca ggtgaaagta aggccctagc aattgttaat
     7981 ctttgcttct gaccacctga caaaatctta gcattttcat ctaattgtgt attaaatcct
     8041 aatggcaatt tttcaatgtc attctttatc tccgcgattt ggcaagcttc ttctatctct
     8101 ttttcagtta tattcttacg acttcccaac aaaagattct ctttaatggt acctgcaaaa
     8161 atatatggag tttgtggcac ataattcaca tatgagcgta aaacatgctt atttatactt
     8221 ctagtcgaat gaccattaaa agttactttt ccttttgtgg gactgaaaaa atcaaccaac
     8281 aatttaacca tagttgactt acctgatcca ctcattccca caatagttaa tttctcatta
     8341 tctttgatcg tcaaattaat atcttttaag acatcttcac catatccata acgataatcg
     8401 acatgtgaga aattaatgtc tccatttaaa tcatgactat cattaactga agttttgccc
     8461 ttaaattcac tttgaactaa ataaacttca tttaaacgat tctgagctac atttgcagct
     8521 tgaagtgtag gttgcaagtt aataatattt tgtaatggat caataaaata tgataataat
     8581 gcattaaatg ccatcaattc accaatagac atttgattat gcattacaac acttgccccc
     8641 acccaaagaa taatgacatt cagtgataat ctaataaaag ttttcaaagc agtttgaaaa
     8701 gcttctgttt tgctatactt aaaagctttt tttaaataat caacaaactg actatcaatt
     8761 tttcgataac gtacttgttc actgtttaat gctttaatcg tctcaattcc ttgaatatct
     8821 tcaataattg atgaactaac taccgcatta ctttccatct ggtcattatt taatctttca
     8881 aacctttttg aaaagccgag aataacaata gcatagagtg gtaatgaagc tagcgtaatc
     8941 aaaaacaatg tcatgttttg aaccgccaaa attataccca ttaaaattac aattgaaaga
     9001 tcaaggaata atgaaatcac cgtacttgcc aatgcatcta taattctact tgcatcagaa
     9061 aaacgagaag taatctcacc agtttttctg gtagtaaaaa attccatcgg taattcaaaa
     9121 atatgcttaa tgtattgtaa attaagatcg attgataacc gctgccccaa aacattcaat
     9181 aaaaattgct gaccatatga aaaaattgag ttaaagacat atgcaatcaa taacccaata
     9241 gctaaaacag ataacgtggt aaatgtaccg ttaggaatat atgtatcaat caacccttgt
     9301 acaaaatatg agctacagat actaatcagt gtcatcagca aagcagctaa aataatgttt
     9361 ctaactaact ttttctgttt aaacatataa gggaataatg ataatagatt attctttttc
     9421 tcctttacag gcttaaaatc tgccttaggc accataaaca atgtaatacc tgtccactct
     9481 ttttcaaacg cctttttgga cattttttta attccactag taggatcagg atcggctacg
     9541 attatttttc ttttagtact tttaagaact acataataat gtaacaatcc tccatctttt
     9601 atcacatgaa caataaaagg atattgaata tctttcatat tgaataagga catatctgct
     9661 tttaccgctt gaacatccat attgaatttt tccgcagttt taactaatcc taaagcagta
     9721 gttccttcag tattggtttt agcaatatga cgtaaatgtg ctattgatac ttgagaatga
     9781 taattcttta agatcattgc taaacaagct gcaccacagt ctgtttcatc gatttgtgga
     9841 acataaattg atttatacgt taacatgccc atcatttatc tctttctgct tagctaattt
     9901 ctctgtttta taattatatc tagcaagaaa atctttcatc attttcacac tactacgtga
     9961 aaaatcttca acatccccat taacaaatga gacacgatgc tgtttcaaat caatcgactc
    10021 aatgttcttc ggattcacca aacaagactg gttaatcttc tctaacatag gattttcttt
    10081 agcatattga ttaatactac ctaaaagttg catttcacct gtcgtcaaga tcattaataa
    10141 cttgtgcggg gttatagttg ttgaaatata aataatatca tcaatattga cattcctagt
    10201 ttgacgtcca attttatacg aaaaagtcat tttcttcata taattgaatt tgtgtaagtt
    10261 gtagatagct acttctacag tctttaccat catctgtcta aatttatcca aatcagatgt
    10321 ttttacaatg tagtcaattg gacctaatcg tcttctgaat gtaattaatg ataagtctgc
    10381 atgactagtt acaaagataa tttgagctcg ttcatctcgc tttttaatta aggcagccag
    10441 atcaaagcca gtatcttctt ccgtatcacc gcctaattca acatcaagaa agtagatacc
    10501 accatctaat ttatgtttct tcagataatc aattgcaccc atgtaatcag ttgaagatgc
    10561 aattgaaaat tcaatttctt catcatctga caaaatcatt tccgcagcac caagaatttt
    10621 cttagtttgc tcaatttgat tttgatcatc atcacaaata aatactggat attgcatttt
    10681 ttatttttca gtcccacttt cactatcagg caaaattgtt aaatcaaaag taaaccaccc
    10741 atcatcaaca tagtaattaa caatcattga atcttcatat ttatgagtaa tttcttttac
    10801 attcgctagt cctaaaccca tatgatgttt cttggttgta taattctttt gacttatttt
    10861 atctgtcgct actccacttt ttctaacgcg atttcgaatt tcaaactcga aatcgccgtt
    10921 ttcttgataa tacattgcat ctattcgcgc actattagag ttacctgttt ctttgatcaa
    10981 ggcctgactt tcttctgcag cattatcaaa cgtgatacca attattctga ccagatctaa
    11041 aatattaaca ctatcaggaa ttcgagaaat gtcgtgttca caatcgaaac tataatctag
    11101 acctaaacta taaagtttag acaacttagc aattgcgata cttttcaagt tcttctcatg
    11161 gatatgattt acaccattat atttacgcaa agccttttta ttaaattgcg tttcagtata
    11221 ctgatcaagt atttttacaa cttctgcagt attaccttct tgagcactta cttttaagcc
    11281 atttaaaata ttttgatagt cgtgtttgaa acgatgcaaa tcatcttcat ttttatcaag
    11341 ataatttgaa tattcctgta attgttccat ctcagaactc aattgctgct gtttaagaat
    11401 cagttcctta ttttctgctt cttttgcttt tctatcagca tttgctagtt caagctgaaa
    11461 tttttgctct ttttgttctt gtttagttag aaggcctttt tgcactttaa tgatagctat
    11521 ataagtaatt acagagaaaa ctatctgaag cactaataaa ctcaaagaca cttcaaaaac
    11581 tatagtcata tgtgtacttt tcaatgctaa aaaatacaca atagagcttg ataaataaac
    11641 gtaaaatatt aatccaataa aaatcgaact atttcgatca tttagtaact tacgaatttt
    11701 taaataatac ttttgaatta taactataat tacgaattcc actagcaaaa atacaaaagt
    11761 catgctacta gaactaatat caaaaattaa tagtattatt tcagcactaa ttgttataag
    11821 aagatctaat aattcaaaaa ataaaattgc cccaaaaata aattttactt ttttctcttt
    11881 ttttaccaaa tatgaaaaaa ggaatattaa aaacgcttga ataatatcta ctaaaaaatc
    11941 atctatttgt actacactac cagctaatac gcatgttcca ataaaaacta tcgaaaatgc
    12001 ataatcttct ctcttaaact tccagcctga caatcgataa aaaatataca aatcaattac
    12061 aggagaaaat aaagcttgaa aaaacatttt ctattttaat ccaaaaattt gaaactgtca
    12121 aatcttttgt gtaaatagat ctttctcgta aattgatttt ttaattattt atttaatcaa
    12181 agtaggattc taaggtgtcc tgaacctgac caaagccttt atgaattcga ttgaaataac
    12241 ggtcattgta gctcattgcc tggatgccaa taaatacatc aagcgactgt tcagttggaa
    12301 actctgcctt aggcttagct ttgcgcttga tcacattgtt aaatgattca atcatgttag
    12361 tcgaataaat tgaagctctg atctgcttgg gatagttata aaagaccagc agatctggtt
    12421 ctatgtcttt caagcttctg ataacatggc tgtaaacctt gccccatttg gtatagaagt
    12481 catgcaggac agctgtggct tcttctttgt ttgtctgttg atgcacctgt ttgaattcgt
    12541 tcatgatctt ttcacgatcg tcgacgcgta ctttagcgca gatattgcgc atgacatgaa
    12601 ccaaacagcg ttgaaaatga gctttaggat aagtcctggc caaggctgtt ttcatgccaa
    12661 caacaccatc agaaagaaaa agctcaactt gctttaagcc tcgggatttc atgttttgaa
    12721 gcatatctgt ccagacttca atgttctcgc taggtgcaat gcagtagtca atgacctcct
    12781 tgtgcccatt aggcttgatg ccaatggcaa tatagactgc ttcacgctca aatgtttctc
    12841 ggcgcaaagg aaggtatgtc gcatccaaat agacgcagaa aaacttgtcg cttagcttgc
    12901 gtttgtggta agcctcaacc tttggaatca tctgcttgga aatatttgat acctgagctg
    12961 gactgtaatg gctgccatac atcttttcaa ttagatcggc tatttccctg gtggtcacgc
    13021 ccttggagta aagcttgata atcatgcttt ccaagatatc cgagtgctgc ttgtagccag
    13081 gcagcgtgtg ctgatgaaat tgaccgttgc gatcccgagg cacttgcact tcaattgggc
    13141 caaattgcgt atcaactttg cggaaataag caccatttct agagttgcca gtattccagc
    13201 catttctggc atagggatca tagcccagaa aggcagtcaa ttcagcttct aacaagttat
    13261 taacagcctg ttgtagctct ttgcgcaata aatcatttat tttgtctgga ttgaatagag
    13321 cttgagcaaa atctttggta aaatcattca tgaaggagtt cttctttctg tatgtgtttt
    13381 tttgttcaaa ccaatcatac gagaaaggaa ctcctttttc taatgtttaa agaaataaat
    13441 ttaaggaatc attcatcctt acacaaacta ttttacagtc tcaaaaattt tcttccagtt
    13501 aaaatgattt ctatgttttt tatttattgt gatatcgtta agagcaaaaa aactaactgt
    13561 aggatcagca aatccaccct taacttcaac taattccttt tcattcaact ttttcataat
    13621 tcaaatttcc tttcaattaa ctaacaattt ttacactatt aatgttacta cacacataat
    13681 ctcacaacta aagtcgtcaa attttgcacc attcaaatca tattctgcat tttcatttaa
    13741 aatgttcctc caccagaacc atttccccat ccccgagaat tactcttgaa gaaatgccgt
    13801 ctaatttttg accgtcctcc aacaattttt tctagaatcg aagtcgacaa ttttcgcatg
    13861 atcttcctct cctttactta aaaattatta tagaaaaatc ataaacctat tctgtttatc
    13921 aaaaatcagc tcatcaaatc ttgcaccatt ttgatcatat tttgcaaaaa atgatcgata
    13981 ttgtacgagt actatccctc cggccaaaaa agatcatcca acgttttatc cagcgcctga
    14041 caaattttga tacataagtt aatcgaggga ttataatttc ccttctcaat cgcagaaatt
    14101 gtctgtcttg aaacatcaat ctgctgcgcc aaatcttctt gcgttaagtc tttaccgact
    14161 cgtgcagcct tcatttttaa atttttcaat ccttatcact ttccttatca cgatggagtt
    14221 gaaacaggct tactactcca ataatcaacc aataaatccc cataatgttc agcgcactgt
    14281 taaagtcatc aatatatcct agaatcaagc aaataccaag tacaacatat agccaactat
    14341 ttgccttaac atgctcttca ttaaatgcaa aatatgctcc atggactata tcgtaaactg
    14401 acatcaccgt taatgacaac ataataattg caaagttaac agcaatacca tgctttgtat
    14461 aaaaatccgt ctgcatgaat aaagcagaaa ttacttctcc aacgattaac acaagaaagc
    14521 catacctgtc accacgacca cgaatcaatt cctgtcgttc atcatacttt gccgcacgac
    14581 gatttcccac gaatacaacg actaagatga aagtcataac tgcaaacaag cttgcaaaag
    14641 ccattaattt taatatttca aattttgaca ttttacacat ccctttcttt taatagtttg
    14701 atattaagcc catatttgca aaatgtaaag tatgttttac atttttacta ataaatttgt
    14761 atttataaaa actagcatta acataatcgg tatcatttcg tgagatttga taccgattat
    14821 ttgttaatga tcctgatttt tcaaaaattt ccttgacttc ttcttttcat cgtcg
//
