LOCUS       gnlProkkaNFIBKKDF_12   10226 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NFIBKKDF_12.
ACCESSION   gnlProkkaNFIBKKDF_12
VERSION     gnlProkkaNFIBKKDF_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:35:52
            Original ID  :: gnl|Prokka|NFIBKKDF_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10226
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10226
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2:10224]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..10224
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10226
                     /SMILES="NC(C(C)C)C(=O)N1C(CCC1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10226
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             3..4175
                     /NRPS_PKS="Domain: Condensation_LCL (1-178). E-value:
                     3.8e-72. Score: 234.7. Matches aSDomain:
                     nrpspksdomains_ctg12_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (345-738). E-value:
                     5.9e-115. Score: 376.0. Matches aSDomain:
                     nrpspksdomains_ctg12_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (843-911). E-value: 2.1e-24. Score:
                     77.4. Matches aSDomain: nrpspksdomains_ctg12_1_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (921-1223). E-value:
                     5.6e-166. Score: 545.3. Matches aSDomain:
                     nrpspksdomains_ctg12_1_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1229-1383). E-value: 5e-52.
                     Score: 167.7. Matches aSDomain:
                     nrpspksdomains_ctg12_1_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 341;
                     E-value: 1.6e-103)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-122, bitscore:
                     395.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 8.1e-16, bitscore:
                     45.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.9e-80, bitscore:
                     254.8, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPA
                     LRIQYKDYAVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVS
                     FTLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEP
                     ILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDMSRN
                     PLFDVMFVLQNMDQESLELDELCLKPAANNGHQTSKFDLTLYAQEQPHGLLTFQMEFST
                     DLYKKKTIEKWLQYFINMLLSIIKDNKAALGTINILNEDETHYLIHELNRTKIDYPRNE
                     TISRLFEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPDSVVALLTGR
                     TPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEKQLLDIECEQ
                     IIIEGIQKQGETKNVDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRLVKNSNYITF
                     TPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIEHQGITTIWL
                     TSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCSEVSIWNGYGPTENTTFS
                     TCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVARGYLGRPDL
                     TKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVRGYRVELGEIESALRQ
                     IDGVKEAAVLARTGQSGSKELFGYISVKAGTNAEQVRSLLARSLPNYMIPAYIIEMETL
                     PLTSNGKLNRKALPEPNFTSKQTYAPPQNDLEDQLVLIWQEVLGIQRIGIEDSFFELGG
                     DSIKALQVSARLGRFGLSLQVSDLFRHPKIKDLSPFIRKSERIIEQGPVQGDVPWTPVQ
                     QWFFSQDIEERHHFNQSVMLFHSGCLSENALRPALKKLAEHHDALRMVYRNDGRRWIQI
                     NQGIHESQLYSLRTSDLSQSESGWETQIKQEVADLQQSINLQEGPLLHAALFKTLTGDY
                     LFLAIHHLVVDGVSWRILLEDLSAGYQQATSGQTIQLPPKTDSYQEYARRIQEYAQSSK
                     LIREEAYWRSVEEQQAAELPYEIPHHVNIDSSKRDSLSFSLTEADTAVLLQNVNYAYGT
                     DTQDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTVGWFTSMYPALISFE
                     NHRDELGTAVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEISFNYLGQFND
                     IERQDTFRPSSLGSRKDITHTWKREQIIEMSAMAADKKLHFNLSYPPACFHKNTMEQLI
                     NRIEHFLLDIMKHCAGQQKAEKTLSDFSSQSLTAEDLDSISSLVEEL"
     aSDomain        6..536
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.80E-72"
                     /label="ctg12_1_Condensation_LCL.1"
                     /locus_tag="ctg12_1"
                     /protein_end="178"
                     /protein_start="1"
                     /score="234.7"
                     /tool="antismash"
                     /translation="QIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNRNLPAL
                     RIQYKDYAVWQEGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSF
                     TLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPI
                     LGMFVNTLALRTRP"
     aSModule        6..4151
                     /complete
                     /domains="nrpspksdomains_ctg12_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg12_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg12_1_PCP.1"
                     /domains="nrpspksdomains_ctg12_1_Epimerization.1"
                     /domains="nrpspksdomains_ctg12_1_TIGR01720.1"
                     /locus_tags="ctg12_1"
                     /monomer_pairings="Val -> D-Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       51..116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0001"
                     /evalue="5.10E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg12_1"
                     /protein_end="38"
                     /protein_start="16"
                     /score="31.8"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNILIREFGELY"
     CDS_motif       147..176
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0002"
                     /evalue="1.30E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg12_1"
                     /protein_end="58"
                     /protein_start="48"
                     /score="14.6"
                     /tool="antismash"
                     /translation="QYKDYAVWQE"
     CDS_motif       438..527
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0003"
                     /evalue="1.60E-15"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg12_1"
                     /protein_end="175"
                     /protein_start="145"
                     /score="49.4"
                     /tool="antismash"
                     /translation="DIIVGSPIAGRPHKDLEPILGMFVNTLALR"
     CDS_motif       576..695
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0004"
                     /evalue="1.00E-22"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg12_1"
                     /protein_end="231"
                     /protein_start="191"
                     /score="72.6"
                     /tool="antismash"
                     /translation="RETALEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVL"
     aSDomain        1038..2216
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_AMP-binding.1"
                     /evalue="5.90E-115"
                     /label="ctg12_1_AMP-binding.1"
                     /locus_tag="ctg12_1"
                     /protein_end="738"
                     /protein_start="345"
                     /score="376.0"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPD
                     SVVALLTGRTPELIAGMLGILKAGGAYLPIASDLPVERIAYMLSDSGAALLLQSEKTEK
                     QLLDIECEQIIIEGIQKQGETKNVDSSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRL
                     VKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIE
                     HQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCSEVSIWNGY
                     GPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAYILNQWGVLQPVGAVGELCVGGDGVA
                     RGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLPDGTIEYVGRIDDQVKVR"
     CDS_motif       1224..1262
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0005"
                     /evalue="1.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_1"
                     /protein_end="420"
                     /protein_start="407"
                     /score="14.8"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       1449..1505
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0006"
                     /evalue="1.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_1"
                     /protein_end="501"
                     /protein_start="482"
                     /score="33.1"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGKPKGVMIE"
     CDS_motif       2010..2099
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0007"
                     /evalue="4.90E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_1"
                     /protein_end="699"
                     /protein_start="669"
                     /score="57.2"
                     /tool="antismash"
                     /translation="PVGAVGELCVGGDGVARGYLGRPDLTKEKF"
     CDS_motif       2181..2246
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0008"
                     /evalue="2.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_1"
                     /protein_end="748"
                     /protein_start="726"
                     /score="38.9"
                     /tool="antismash"
                     /translation="YVGRIDDQVKVRGYRVELGEIE"
     aSDomain        2532..2735
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_PCP.1"
                     /evalue="2.10E-24"
                     /label="ctg12_1_PCP.1"
                     /locus_tag="ctg12_1"
                     /protein_end="911"
                     /protein_start="843"
                     /score="77.4"
                     /tool="antismash"
                     /translation="EDQLVLIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRFGL
                     SLQVSDLFRHPKIKDLSPFIRKS"
     aSDomain        2766..3671
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_Epimerization.1"
                     /evalue="5.60E-166"
                     /label="ctg12_1_Epimerization.1"
                     /locus_tag="ctg12_1"
                     /protein_end="1223"
                     /protein_start="921"
                     /score="545.3"
                     /tool="antismash"
                     /translation="GDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGCLSENALRPALK
                     KLAEHHDALRMVYRNDGRRWIQINQGIHESQLYSLRTSDLSQSESGWETQIKQEVADLQ
                     QSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQATSGQTIQ
                     LPPKTDSYQEYARRIQEYAQSSKLIREEAYWRSVEEQQAAELPYEIPHHVNIDSSKRDS
                     LSFSLTEADTAVLLQNVNYAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHIL
                     PELDISRTVGWFTSMYPALIS"
     CDS_motif       2778..2804
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0009"
                     /evalue="3.80E-03"
                     /label="NRPS-E1"
                     /locus_tag="ctg12_1"
                     /protein_end="934"
                     /protein_start="925"
                     /score="10.5"
                     /tool="antismash"
                     /translation="WTPVQQWFF"
     CDS_motif       2904..2954
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0010"
                     /evalue="1.70E-03"
                     /label="Cy2"
                     /locus_tag="ctg12_1"
                     /protein_end="984"
                     /protein_start="967"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LAEHHDALRMVYRNDGR"
     CDS_motif       3147..3212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0011"
                     /evalue="1.50E-12"
                     /label="NRPS-E2"
                     /locus_tag="ctg12_1"
                     /protein_end="1070"
                     /protein_start="1048"
                     /score="39.6"
                     /tool="antismash"
                     /translation="LFLAIHHLVVDGVSWRILLEDL"
     CDS_motif       3618..3665
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0012"
                     /evalue="6.70E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg12_1"
                     /protein_end="1221"
                     /protein_start="1205"
                     /score="27.7"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPAL"
     aSDomain        3690..4151
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_1_TIGR01720.1"
                     /evalue="5.00E-52"
                     /label="ctg12_1_TIGR01720.1"
                     /locus_tag="ctg12_1"
                     /protein_end="1383"
                     /protein_start="1229"
                     /score="167.7"
                     /tool="antismash"
                     /translation="ELGTAVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEI
                     SFNYLGQFNDIERQDTFRPSSLGSRKDITHTWKREQIIEMSAMAADKKLHFNLSYPPAC
                     FHKNTMEQLINRIEHFLLDIMKHCAGQQKAEKTLSDFSSQSLTAEDLDSI"
     CDS_motif       3714..3776
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0013"
                     /evalue="1.40E-09"
                     /label="NRPS-E6"
                     /locus_tag="ctg12_1"
                     /protein_end="1258"
                     /protein_start="1237"
                     /score="30.2"
                     /tool="antismash"
                     /translation="VKDTLGRIPNKGVGYGMLKYL"
     CDS_motif       3816..3845
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_1_0014"
                     /evalue="4.50E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg12_1"
                     /protein_end="1281"
                     /protein_start="1271"
                     /score="9.6"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     aSDomain        4201..4290
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_NRPS-COM_Nterm.1"
                     /evalue="1.80E-18"
                     /label="ctg12_2_NRPS-COM_Nterm.1"
                     /locus_tag="ctg12_2"
                     /protein_end="30"
                     /protein_start="0"
                     /score="57.4"
                     /tool="antismash"
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDS"
     CDS             4201..10224
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 1.8e-18.
                     Score: 57.4. Matches aSDomain:
                     nrpspksdomains_ctg12_2_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-304). E-value:
                     2.1e-118. Score: 386.6. Matches aSDomain:
                     nrpspksdomains_ctg12_2_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (468-865). E-value:
                     7.3e-105. Score: 342.7. Matches aSDomain:
                     nrpspksdomains_ctg12_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (971-1040). E-value: 2.9e-24. Score:
                     77.0. Matches aSDomain: nrpspksdomains_ctg12_2_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1055-1333). E-value:
                     5.7e-104. Score: 339.1. Matches aSDomain:
                     nrpspksdomains_ctg12_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1499-1900). E-value:
                     2.2e-112. Score: 367.5. Matches aSDomain:
                     nrpspksdomains_ctg12_2_AMP-binding.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     386.2; E-value: 4e-117)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_2"
                     /sec_met_domain="Condensation (E-value: 6.6e-89, bitscore:
                     285.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-16, bitscore:
                     48.2, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-121, bitscore:
                     392.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKANSIQDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKV
                     NPQFFQNSINALVERHDIFRTIFISQNVSSPQQVVLRERNIIVLEEDITHLNEAEQSQF
                     IEQWKEKDRDRGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHI
                     YASYVNASPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGK
                     SRQEHVTFSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGR
                     PAEIEGIEHMVGLFINTMPVRVQGAKTPFLQLIKDMQKDRLAAEAYSYHPLYEIQSRSA
                     VKQGLIDHILVFENYPVQQEIQMLNKQEHATDLFQIHNFTVADETNYSFYLMVAPGEEI
                     HIKMNYDAEQHDRSFVLSVKEHLLNAVSQILNNPNLPPEEIDITTDTEKRQLIGEITDR
                     TPVYETIHAMFEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQEPVA
                     IMMDRSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSSSLED
                     NYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLLKFEY
                     THSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFINKHQT
                     NIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRERGIHLHNHYG
                     PSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISGASVA
                     RGYVNHDKLTSDKFSSDPFKPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIRGYRIEP
                     QEIEVTLMNHPDISEAAILIWQDQNGEHELCAYYCSVQKLNAIDLRSYMASELPEYMIP
                     AKWIWVDSIPLTPNGKVDRAALPGPDASISGNPYTAPRNLLEAKLSQLFEDVLNNGHIG
                     IQDNFFDHGGHSLKATVLMSRIAKEFHVQVSLKDIFAHPTVEGLASIIREAEQNPYAAI
                     EPAEERGTYPVSSAQKRMYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCKELINRHE
                     PLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGLIEVSNEKH
                     VLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKGDSYQKQE
                     TYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKNRSTLYMT
                     LLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRPAGNKTFEEFL
                     KEVRQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVLQNMEQQKLKMNDVQLQ
                     WNDLVHPISKFDISLYVTEHDSELFCQFEYSTALFEKETIQRWASLFTTLVEHTAASPE
                     TELDNIPILTKEEERDFIESCHLFEETGYSMNQTLHYALEQQAAKTPDQAAVIFEDGVM
                     TYKELNEQANRIAWELIGRGVKPETTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYP
                     EERISFLLEDSGTNILLLQSAGLHVPEFTGEIVYLNQTNSGLAHRLSNPNVDVLPQSLA
                     YVIYTSGSTGMPKGVEIEHRSAVNFLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWW
                     PYAGASVYLLPQGGEKEPEVIVKAIEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRL
                     KRVFSGGEQLGTHLVSRFHELLPNVSITNSYGPTEATVEAAFFDCPLHEKLERIPIGKP
                     VHHVRLYILNQNHRMLPAGCIGELYIAGAGVARGYLNRPALTEEHFLEDPFYPGERMYK
                     TGDVARWLPDGNVEFLGRLDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEP
                     ELCAYVEGLQRNEVRAQLESLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADA
                     ETYTAPRNVTEMKLSQ"
     aSDomain        4222..5112
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.10E-118"
                     /label="ctg12_2_Condensation_DCL.1"
                     /locus_tag="ctg12_2"
                     /protein_end="304"
                     /protein_start="7"
                     /score="386.6"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKDSQAYVEQASFTIEGKVNPQFFQN
                     SINALVERHDIFRTIFISQNVSSPQQVVLRERNIIVLEEDITHLNEAEQSQFIEQWKEK
                     DRDRGFHLQKDVLMRIALIQTGESQYSCIWTFHHIMMDGWCLSIVLKEFLHIYASYVNA
                     SPITLEPVQPYGKYIKWLMEQDKEQAVSYWDHYLSGHEQQTVLPKQKKTKGKSRQEHVT
                     FSFSKEESSRLSELAAREEVTLSTIFHTIWGILLQKYNNNDDAVFGSVISGRPAEIEGI
                     EHMVGLFINTMPVRVQ"
     aSModule        4222..7320
                     /complete
                     /domains="nrpspksdomains_ctg12_2_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg12_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg12_2_PCP.1"
                     /locus_tags="ctg12_2"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4231..4272
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0001"
                     /evalue="9.40E-05"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg12_2"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.4"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS_motif       4294..4407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0002"
                     /evalue="1.30E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg12_2"
                     /protein_end="69"
                     /protein_start="31"
                     /score="49.6"
                     /tool="antismash"
                     /translation="AYVEQASFTIEGKVNPQFFQNSINALVERHDIFRTIFI"
     CDS_motif       4627..4692
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0003"
                     /evalue="5.30E-11"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg12_2"
                     /protein_end="164"
                     /protein_start="142"
                     /score="34.9"
                     /tool="antismash"
                     /translation="FHHIMMDGWCLSIVLKEFLHIY"
     CDS_motif       4738..4776
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0004"
                     /evalue="1.30E-02"
                     /label="C4_DCL_171-183"
                     /locus_tag="ctg12_2"
                     /protein_end="192"
                     /protein_start="179"
                     /score="8.6"
                     /tool="antismash"
                     /translation="PYGKYIKWLMEQD"
     CDS_motif       5011..5106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0005"
                     /evalue="1.00E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg12_2"
                     /protein_end="302"
                     /protein_start="270"
                     /score="62.9"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPAEIEGIEHMVGLFINTMPVR"
     CDS_motif       5152..5268
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0006"
                     /evalue="1.90E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg12_2"
                     /protein_end="356"
                     /protein_start="317"
                     /score="65.3"
                     /tool="antismash"
                     /translation="QKDRLAAEAYSYHPLYEIQSRSAVKQGLIDHILVFENYP"
     aSDomain        5605..6795
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_AMP-binding.1"
                     /evalue="7.30E-105"
                     /label="ctg12_2_AMP-binding.1"
                     /locus_tag="ctg12_2"
                     /protein_end="865"
                     /protein_start="468"
                     /score="342.7"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FEKQAEKTPDAHAVIDQACSLTYRELNKAANRLARHLRMKGVVRQ
                     EPVAIMMDRSAAFITGVLGILKAGGAIVPVDPHYPADRIRYILHDCGCSHVVSQAHLSS
                     SLEDNYIITHPEDIESKVDGSNIKSVNNADDLLYMIYTSGTTGKPKGVQFEHRNMANLL
                     KFEYTHSGIDFEADVLQFATPSFDVCYQEIFSALLKGGTLHIVPEAIKRDVPQLFAFIN
                     KHQTNIVFLPTAFIKMIFSERELANSFPDGVKHLIAAGEQLMISDLFQDVLRERGIHLH
                     NHYGPSETHVVSTYTIHPGDPIPELPPIGKPIGCTDLYILNHQKQLQPCGVPGELYISG
                     ASVARGYVNHDKLTSDKFSSDPFKPGVIMYRTGDLARRLEDGNIEYIGRADNQVKIR"
     CDS_motif       5791..5832
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0007"
                     /evalue="5.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_2"
                     /protein_end="544"
                     /protein_start="530"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LGILKAGGAIVPVD"
     CDS_motif       6016..6072
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0008"
                     /evalue="1.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_2"
                     /protein_end="624"
                     /protein_start="605"
                     /score="26.8"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVQFEH"
     CDS_motif       6454..6480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0009"
                     /evalue="4.50E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg12_2"
                     /protein_end="760"
                     /protein_start="751"
                     /score="4.1"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       6589..6678
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0010"
                     /evalue="6.80E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_2"
                     /protein_end="826"
                     /protein_start="796"
                     /score="40.8"
                     /tool="antismash"
                     /translation="PCGVPGELYISGASVARGYVNHDKLTSDKF"
     CDS_motif       6760..6825
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0011"
                     /evalue="6.60E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_2"
                     /protein_end="875"
                     /protein_start="853"
                     /score="37.3"
                     /tool="antismash"
                     /translation="YIGRADNQVKIRGYRIEPQEIE"
     CDS_motif       7033..7059
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0012"
                     /evalue="4.50E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg12_2"
                     /protein_end="953"
                     /protein_start="944"
                     /score="4.0"
                     /tool="antismash"
                     /translation="GKVDRAALP"
     aSDomain        7114..7320
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_PCP.1"
                     /evalue="2.90E-24"
                     /label="ctg12_2_PCP.1"
                     /locus_tag="ctg12_2"
                     /protein_end="1040"
                     /protein_start="971"
                     /score="77.0"
                     /tool="antismash"
                     /translation="EAKLSQLFEDVLNNGHIGIQDNFFDHGGHSLKATVLMSRIAKEFH
                     VQVSLKDIFAHPTVEGLASIIREA"
     aSDomain        7366..8199
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.70E-104"
                     /label="ctg12_2_Condensation_LCL.1"
                     /locus_tag="ctg12_2"
                     /protein_end="1333"
                     /protein_start="1055"
                     /score="339.1"
                     /tool="antismash"
                     /translation="TYPVSSAQKRMYVLQQLDEGVAYNMPAVLELEGALDVAKLSAVCK
                     ELINRHEPLRTSFVSGADDEPVQRIHTEVPFTLSKETTIEGFVRPFDLSQAPLFRAGLI
                     EVSNEKHVLLVDMHHIISDGVSVQLLIREFTDLYANRQLKPLRIQYKDYAVWQQKFKKG
                     DSYQKQETYWQQQFSGDLPILELPTDKRRPAERQFIGGKVTFQLDKEITARIKRLAHKN
                     RSTLYMTLLALYSAFLSRLSGQDDIVIGSPIAGRPHADLEAVLGMFVNTLALRTRP"
     aSModule        7366..9900
                     /domains="nrpspksdomains_ctg12_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg12_2_AMP-binding.2"
                     /incomplete
                     /locus_tags="ctg12_2"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       7429..7542
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0013"
                     /evalue="4.00E-15"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg12_2"
                     /protein_end="1114"
                     /protein_start="1076"
                     /score="48.2"
                     /tool="antismash"
                     /translation="AYNMPAVLELEGALDVAKLSAVCKELINRHEPLRTSFV"
     CDS_motif       7714..7779
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0014"
                     /evalue="1.80E-09"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg12_2"
                     /protein_end="1193"
                     /protein_start="1171"
                     /score="30.1"
                     /tool="antismash"
                     /translation="MHHIISDGVSVQLLIREFTDLY"
     CDS_motif       7810..7842
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0015"
                     /evalue="3.30E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg12_2"
                     /protein_end="1214"
                     /protein_start="1203"
                     /score="13.3"
                     /tool="antismash"
                     /translation="QYKDYAVWQQK"
     CDS_motif       8101..8190
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0016"
                     /evalue="2.70E-16"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg12_2"
                     /protein_end="1330"
                     /protein_start="1300"
                     /score="51.9"
                     /tool="antismash"
                     /translation="DIVIGSPIAGRPHADLEAVLGMFVNTLALR"
     CDS_motif       8239..8358
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0017"
                     /evalue="6.60E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg12_2"
                     /protein_end="1386"
                     /protein_start="1346"
                     /score="66.7"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPFEELVDKLGVQREMSRNPLFDTTLVL"
     aSDomain        8698..9900
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg12_2_AMP-binding.2"
                     /evalue="2.20E-112"
                     /label="ctg12_2_AMP-binding.2"
                     /locus_tag="ctg12_2"
                     /protein_end="1900"
                     /protein_start="1499"
                     /score="367.5"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="LEQQAAKTPDQAAVIFEDGVMTYKELNEQANRIAWELIGRGVKPE
                     TTVAIIGKRSPEMLLGIYGILKAGGAYLPIDPDYPEERISFLLEDSGTNILLLQSAGLH
                     VPEFTGEIVYLNQTNSGLAHRLSNPNVDVLPQSLAYVIYTSGSTGMPKGVEIEHRSAVN
                     FLNSLQSRYQLKHSDMIMHKTSYSFDASIWELFWWPYAGASVYLLPQGGEKEPEVIVKA
                     IEEQKITAMHFVPSMLHAFLEHIKYRSVPIKTNRLKRVFSGGEQLGTHLVSRFHELLPN
                     VSITNSYGPTEATVEAAFFDCPLHEKLERIPIGKPVHHVRLYILNQNHRMLPAGCIGEL
                     YIAGAGVARGYLNRPALTEEHFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRLDDQVK
                     IR"
     CDS_motif       8887..8925
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0018"
                     /evalue="8.50E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg12_2"
                     /protein_end="1575"
                     /protein_start="1562"
                     /score="15.8"
                     /tool="antismash"
                     /translation="GILKAGGAYLPID"
     CDS_motif       9112..9171
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0019"
                     /evalue="9.80E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg12_2"
                     /protein_end="1657"
                     /protein_start="1637"
                     /score="30.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGMPKGVEIEH"
     CDS_motif       9556..9585
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0020"
                     /evalue="4.30E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg12_2"
                     /protein_end="1795"
                     /protein_start="1785"
                     /score="7.0"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       9694..9783
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0021"
                     /evalue="6.70E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg12_2"
                     /protein_end="1861"
                     /protein_start="1831"
                     /score="53.5"
                     /tool="antismash"
                     /translation="PAGCIGELYIAGAGVARGYLNRPALTEEHF"
     CDS_motif       9865..9930
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0022"
                     /evalue="1.10E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg12_2"
                     /protein_end="1910"
                     /protein_start="1888"
                     /score="39.7"
                     /tool="antismash"
                     /translation="FLGRLDDQVKIRGYRIEPGEIE"
     CDS_motif       10126..10152
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg12_2_0023"
                     /evalue="4.90E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg12_2"
                     /protein_end="1984"
                     /protein_start="1975"
                     /score="3.9"
                     /tool="antismash"
                     /translation="GKLDRNALP"
ORIGIN
        1 gtgcccaaat cgtaaagata tcagatgagc ggcacctgtt gctggttgat atgcatcaca
       61 tcatttcaga cggtgtttcc gtcaacattc tgattcggga attcggcgag ctgtacaata
      121 atcggaatct tccggcactg cgcattcaat ataaagatta tgccgtatgg caagaaggat
      181 tcaaaacagg agacgcgtac aaaacgcaag aggcgtactg gctgaagcag ctcgagggcg
      241 agctgcctgt gctggatctt ccggctgatc atgcccgccc gccggtgcga agcttcgcgg
      301 gtgacaaggt ctcatttacg ctggatcaag aggttgcatc aggccttcac aagctggcac
      361 gagaaaacgg aagcacactg tacatggtgc tccttgcggc ttacaccgcg ttcttgtcac
      421 gcttaagcgg acaggaagat atcatcgtcg gctcgccaat tgccggccgg ccgcacaagg
      481 atcttgagcc gatactcgga atgtttgtga acacgctggc gcttcggaca cgcccggagg
      541 gcgggaagcc attcgtacag tatttgcagg aagtgcgtga gacagcattg gaagcctttg
      601 agcaccaaga ttacccgttc gaagagcttg tcgataagct tgaattgaca cgggacatga
      661 gccggaatcc gctgtttgac gtaatgtttg ttcttcaaaa catggatcag gaatcgttgg
      721 aactggatga actttgtctc aaacctgcag caaacaatgg gcatcaaacg tccaaatttg
      781 atttaaccct atatgcccag gaacagcccc acggtttgct gacgttccaa atggagttta
      841 gtactgactt atataagaaa aaaacgatag aaaagtggct tcaatacttc atcaatatgt
      901 tactctccat catcaaagac aacaaagccg ctctcggaac aataaatatc ctgaatgagg
      961 atgagaccca ttaccttatc cacgagctca atcgtacaaa aatagattat ccaagaaatg
     1021 aaaccatcag cagactcttt gaaatgcagg cagaacaaac gcctaatgct gtagcaattg
     1081 tcagcgacac ccaagtattt acttacgagg acctgaacag ctgggcaaat caaattgcct
     1141 cagttctaca gattaagggt gtagggcctg atagtgttgt agccttgttg acaggcagaa
     1201 caccagaact cattgcagga atgctgggca ttctgaaagc cgggggagcc tatctgccta
     1261 ttgcttctga tctgcctgtt gaacgaatag cttatatgct gtcagacagc ggggcggcat
     1321 tactccttca atctgaaaaa acagagaaac agctattaga cattgaatgt gaacaaatca
     1381 taatcgaagg tattcaaaag caaggagaaa cgaagaacgt tgattcttca gcagggccac
     1441 attcacttgc atatatcatt tatacctctg gatcaaccgg taaaccaaag ggtgtcatga
     1501 ttgagcagcg aagtgtaatt cgtcttgtta aaaacagcaa ttatattaca tttacacctg
     1561 aagaccgcct tcttatgaca tcatcaatcg gtttcgacgt tgggtcattt gaaattttcg
     1621 gaccgctgct aaatggtgcc gctttgcatc tgtccgatca acaaacattt ctcgattccc
     1681 atcagcttaa gaggtacata gaacatcaag gaatcacaac gatttggctg acatcttctc
     1741 tattcaatca tttgacagaa caaaatgaac aaacattttc acagctgaaa catttgatta
     1801 taggcggaga agctttgtcg ccgagccacg tcaatcgaat cagaaatgtc tgctctgaag
     1861 tatcgatatg gaatggatat ggccctaccg aaaatacaac tttttcgaca tgccttcaca
     1921 ttcaaaaaac atatgaactt tccattccga tcgggcggcc ggttggtaat tccaccgctt
     1981 atatcttaaa tcaatgggga gtgctgcagc cggtcggagc tgtcggtgaa ctttgtgtcg
     2041 gcggagatgg cgtcgccaga ggatatttgg gccgtcctga tttaacgaaa gagaaatttg
     2101 tcccacatcc atttgcacct ggcgatcgac tgtatcgcac aggtgatctg gcgcgctggc
     2161 ttcctgatgg cacaattgag tacgttggcc gtattgatga tcaagtaaaa gtcagaggct
     2221 atcgtgtgga gctgggtgag atcgaatcag cacttcgcca aatagacgga gtcaaagaag
     2281 cggcggtgtt ggcacgtaca ggacagtcag ggagcaaaga gctgtttggc tatatcagcg
     2341 taaaagcagg cacgaatgct gaacaagtgc gttctcttct tgcgcgttcg ctgccaaact
     2401 atatgatccc ggcgtacatt attgaaatgg agactcttcc gctcacatca aacggcaaat
     2461 tgaaccgaaa agcacttcct gaaccaaatt tcacatctaa acaaacgtac gctccgcctc
     2521 aaaatgacct tgaagaccaa cttgtgttga tctggcagga ggttctcggc atccagagga
     2581 tcggaataga ggattcgttt tttgaattgg gcggagattc aatcaaagcc cttcaagttt
     2641 ctgcacgcct tggacgcttt gggctaagct tgcaggtaag tgatttattc cgtcatccaa
     2701 agataaagga cttatcacca tttatccgta agtcagagag aatcatagag caaggacccg
     2761 ttcagggtga cgttccttgg acgcctgttc agcaatggtt tttttcacag gatattgaag
     2821 aaagacacca tttcaatcag tctgtcatgc tattccattc tggatgtttg tctgaaaacg
     2881 cccttagacc agccttgaaa aaactggcgg agcatcatga tgcgcttcgg atggtttatc
     2941 gcaacgatgg caggcgatgg attcaaatca accaaggcat tcatgagtca cagctataca
     3001 gcttaagaac ctctgatctt tcacagtcag aaagcggctg ggagacgcaa atcaaacaag
     3061 aagttgcaga tcttcagcaa agcatcaatt tgcaggaagg accgttgttg cacgccgctt
     3121 tgtttaaaac actgaccgga gattacttgt tccttgcgat ccatcacctt gtcgttgatg
     3181 gtgtctcatg gcggattttg ctggaggatt tgtcagccgg atatcaacaa gctacttcag
     3241 gccagacgat ccagcttccg cctaaaacgg attcctacca ggaatacgca agacgcatac
     3301 aggaatatgc ccaaagcagt aagctgattc gcgaagaggc gtattggcga agtgtagaag
     3361 aacagcaagc cgcagaactg ccatatgaaa taccgcatca tgtgaacatc gactccagca
     3421 aaagggactc attaagcttt tcactgactg aagcagacac cgccgtcttg ctgcaaaacg
     3481 tcaattacgc ctatggcaca gatacacaag atattctgtt aaccgcagca tccttggcga
     3541 tttgtgaatg gacaggcgga agcaagctcc gtatcgctat ggaaggacac gggagagaac
     3601 acattctgcc agagttagat atcagcagga cggtcggctg gtttacatcc atgtacccgg
     3661 ccctcataag ctttgaaaat catagagatg agctcggaac cgcagtaaaa accgttaaag
     3721 atacactggg ccggatacca aacaaagggg taggttacgg tatgctgaaa taccttacac
     3781 atcctgaaaa taaaagcatt acgttttcaa aaacacctga aatcagcttt aactatttgg
     3841 gccagttcaa cgacatcgaa agacaggaca ccttccgccc atcaagcctt ggtagcagaa
     3901 aggatatcac tcatacatgg aagcgtgagc aaatcatcga gatgagcgca atggcagcag
     3961 acaaaaagct ccatttcaat cttagttatc cgccagcctg ctttcacaaa aacacaatgg
     4021 agcagcttat taacaggatt gaacactttt tgctggacat tatgaaacac tgcgccggtc
     4081 aacagaaagc agaaaagaca ctgagcgatt tcagcagtca atcattaacg gcagaggact
     4141 tggacagcat atccagcttg gtggaagaat tgtagaaaat cgtgacaggg agacatgaac
     4201 atgacaaaag cgaattcaat tcaggatatt tatccgctgt cttacatgca ggaagggatg
     4261 cttttccatt ccctcctgca aaaagattca caggcgtatg ttgagcaagc ttcttttaca
     4321 atagaaggaa aagtcaaccc gcagtttttt caaaacagca tcaacgctct tgtagaaaga
     4381 catgatattt tcagaacgat ttttatcagc caaaatgttt cctcccccca gcaggttgtt
     4441 ctgagagaac gaaatatcat cgtcctggaa gaagacatta ctcatttaaa cgaggcggag
     4501 caatcacagt ttatcgagca atggaaagaa aaggaccggg accgggggtt tcatttgcaa
     4561 aaggatgtgc tcatgcgcat cgctcttatt caaacaggag agagccagta ctcctgcatt
     4621 tggacctttc atcatatcat gatggacggt tggtgcctca gcattgtgct aaaggagttt
     4681 ctgcatattt acgcatctta tgtaaatgca tcccctataa cattggagcc ggtccagcca
     4741 tacggaaagt atatcaaatg gctgatggag caagacaaag agcaggcggt ttcttattgg
     4801 gaccattatc tttccggcca cgaacagcaa accgtgctcc cgaagcagaa aaaaacaaag
     4861 ggaaaaagca ggcaggaaca cgttacattt tcattctcta aagaagaaag cagcaggctt
     4921 tcagagcttg ctgctagaga agaagtgaca ctcagtacga tttttcatac catttggggc
     4981 attctgctgc aaaaatataa taataacgat gacgccgtat tcggttctgt catttcagga
     5041 aggcccgcag aaatcgaagg cattgaacat atggtaggtc ttttcattaa tacgatgccg
     5101 gttcgggtgc agggggcaaa aacgccattt cttcaactta taaaagatat gcaaaaagac
     5161 cgtcttgccg ctgaagcgta cagctaccac cctttatatg agattcaatc ccgctcagct
     5221 gttaagcaag ggctgattga tcatattctc gtatttgaaa actatccggt gcagcaagag
     5281 attcaaatgc tgaacaaaca ggaacatgct actgatcttt ttcagattca taatttcact
     5341 gtcgcagatg aaaccaacta cagcttttat cttatggtgg cgccagggga agaaattcat
     5401 atcaaaatga actatgatgc ggagcagcac gatcggtctt ttgtgctctc tgtcaaagag
     5461 catcttctga atgctgtatc acaaatctta aataatccga atcttccacc tgaagaaatc
     5521 gatatcacga cagatactga aaagcggcag ctgattggag aaatcacaga tcgaacacca
     5581 gtttacgaaa ccatccatgc catgtttgaa aagcaagcgg aaaagacacc agatgctcat
     5641 gctgtaattg atcaagcctg ctcattaaca tacagagaac tgaataaagc ggctaacaga
     5701 ttggcacggc atttacgaat gaaaggcgtt gtgagacagg aacccgttgc gattatgatg
     5761 gatcgctctg cggcgtttat caccggcgtt cttggaatct taaaggcagg cggcgccatt
     5821 gttccggttg atccgcatta cccggctgac agaatccgtt atattctgca tgattgcggc
     5881 tgttcgcatg ttgtttcaca agcgcatctt tcctcatcgt tagaagacaa ttacattatc
     5941 actcatccag aagatatcga aagcaaagta gacggcagta acataaagtc agtcaacaat
     6001 gctgacgatc tgctgtatat gatttataca tcaggcacaa caggtaaacc aaagggtgtt
     6061 caatttgagc atcgaaacat ggctaacttg ctgaagttcg aatatactca ctccggcatt
     6121 gactttgaag cagatgttct gcaatttgct acaccttcct tcgacgtctg ctatcaagaa
     6181 atattttctg cgcttctgaa aggcggcaca ctccacatcg tgccagaagc cataaaaaga
     6241 gatgtgcctc agctgtttgc atttataaac aagcatcaga cgaatattgt gtttctccca
     6301 actgctttta tcaaaatgat tttcagcgag cgagaacttg cgaactcgtt tcctgatggc
     6361 gtcaaacacc tgatcgcagc cggggaacaa ttaatgattt cagacctttt ccaagatgtg
     6421 ttgcgtgaac gcggcataca cctgcacaat cattacggac cttcagaaac tcatgtggta
     6481 tctacgtata ccattcatcc tggagaccct attcctgagc ttccgccaat cggtaaaccg
     6541 ataggctgta ctgatctata tattttgaat catcaaaaac agcttcagcc atgcggcgta
     6601 ccaggcgaac tctatatttc cggcgcaagt gttgccagag gatatgtcaa tcacgataaa
     6661 ctgacaagcg acaaattttc atccgatcca ttcaagcctg gtgtgatcat gtaccggaca
     6721 ggtgatttgg ccagacggct tgaagacggc aacatcgaat atatcggacg ggcagacaat
     6781 caagtgaaaa tcagaggtta tcgaattgag ccgcaagaaa tcgaagtcac gttaatgaat
     6841 cacccggaca ttagtgaggc tgccattctc atctggcaag atcaaaacgg tgaacatgaa
     6901 ttatgcgctt actattgcag tgtacaaaag ctgaacgcaa tagatttacg cagttatatg
     6961 gctagtgagc tcccagaata catgattccg gcgaaatgga tatgggttga cagcatacct
     7021 cttaccccaa atggaaaagt agatcgcgca gcacttccgg ggccagatgc ttcaatcagc
     7081 ggaaacccat atactgcccc tcgaaatctg ttagaggcaa agctttcaca actatttgaa
     7141 gatgtactga ataatggcca tataggcatc caagacaact tttttgacca tggcggccac
     7201 tcgttaaaag caacagtgct tatgtcacgg atcgcaaagg aattccatgt gcaagtttcg
     7261 cttaaggaca tctttgctca tccgactgtt gaaggattag cttcaatcat tcgagaggca
     7321 gaacaaaatc cgtatgcagc aattgaacca gcagaagaaa ggggtacata tcctgtatct
     7381 tcggcccaaa aacgaatgta tgtgcttcaa cagcttgatg agggtgtcgc ctataacatg
     7441 cctgcggtct tagaactgga aggtgcactg gatgtcgcca aactgtctgc tgtatgtaaa
     7501 gaactgatca atcggcatga gccgcttcga acttcctttg tatccggagc tgatgacgag
     7561 ccggttcagc gtatccacac cgaagtgccg tttacgttaa gtaaagagac cactatcgag
     7621 ggatttgtcc gtccctttga tctcagccag gcgccattat ttagagcagg ccttatagaa
     7681 gtgtcaaacg agaagcatgt attgctggtg gatatgcacc atatcatttc agatggcgta
     7741 tccgttcagc tcctaatccg agaatttacc gatctttatg caaaccggca gcttaagcca
     7801 ttgcggatcc aatataaaga ttacgccgta tggcagcaga aatttaaaaa gggagactcg
     7861 taccaaaagc aggagactta ctggcagcag cagtttagcg gggatcttcc tatactggag
     7921 cttccaacag ataaacgacg tccggcagaa cggcaattca taggcggaaa agtaaccttt
     7981 caattggaca aagagatcac ggcccgcata aagcggctcg cccataaaaa cagaagcacg
     8041 ctttatatga cgcttctcgc tttgtattca gcctttttgt ctcggttaag cggtcaggat
     8101 gatatcgtga ttggttcacc tatcgccgga cggccccatg ccgaccttga agctgttctt
     8161 gggatgttcg tcaatacact ggctctccgc acacgcccgg cgggtaataa gacgtttgag
     8221 gaatttctga aagaagtcag acagacggca ctagaagcgt atgagcatca ggattacccg
     8281 tttgaagagc ttgtggacaa actcggtgtg cagcgggaaa tgagccggaa tcctttgttt
     8341 gacacaacgc tagtccttca gaatatggaa cagcaaaagc taaaaatgaa tgatgtacag
     8401 cttcagtgga acgacttggt gcacccaata tcaaaatttg atatttccct atacgttaca
     8461 gaacatgatt ccgagctttt ctgtcagttt gaatacagta cagctttgtt tgagaaagaa
     8521 accatccaaa ggtgggccag ccttttcacc acgcttgtgg aacatacagc tgccagtcct
     8581 gaaacagaat tggacaatat tccaatctta acaaaagaag aagagcgaga tttcattgaa
     8641 tcatgccatc tgtttgagga gacgggctat tcaatgaatc aaacgctcca ctatgcactc
     8701 gaacagcagg cagcaaaaac gcctgatcag gcggccgtta tcttcgaaga tggagtgatg
     8761 acctataaag aattgaacga acaggctaac cgtatcgcct gggagctgat cggacggggg
     8821 gtaaaacccg aaacgactgt tgccattata ggaaagcgtt cacctgaaat gctgcttggc
     8881 atttatggca ttcttaaagc tggcggcgct tatctgccca tcgacccgga ttatccggaa
     8941 gaacgaatca gctttctgct ggaggacagc ggtacaaaca ttctcctgct tcagtctgcc
     9001 ggccttcatg ttccggaatt tacaggagag attgtctatc tcaatcagac aaatagcgga
     9061 ctggcacatc gtttgtccaa tccgaatgtg gatgttctcc cgcaatcttt agcctatgtc
     9121 atctatacat ccggctctac cgggatgcct aagggtgttg aaattgaaca tcgatcagcg
     9181 gtgaattttt tgaattccct acagtcccgc tatcagctaa agcattcaga catgattatg
     9241 cacaaaacat cgtattcatt cgatgcttca atatgggagc tgttttggtg gccttatgcc
     9301 ggagcttctg tttatctgct tcctcaggga ggcgaaaaag aacctgaagt gatcgtgaag
     9361 gccatagaag aacaaaagat cacagctatg cattttgtgc cttcaatgct ccatgcattt
     9421 ttagaacata taaaatatcg ctctgtaccg attaagacaa acagactcaa gcgagtgttt
     9481 tctggaggag aacagctggg gacccatctt gtctcccgat ttcacgagtt gcttccaaat
     9541 gtttcaataa ccaattccta tgggccaacg gaagcaaccg tagaagctgc attctttgat
     9601 tgtccgctgc atgaaaaact tgaacggatt ccaattggaa aacctgttca tcatgtcaga
     9661 ttatatatcc tgaatcagaa tcatcggatg ctgcctgctg gatgtatcgg cgaactatac
     9721 attgccggag cgggtgttgc cagaggttat ttgaatcggc cggcattaac ggaggagcat
     9781 tttctagaag acccgtttta cccgggtgaa cgcatgtaca aaacagggga tgtggcgcgc
     9841 tggctccctg acgggaatgt tgaattcctg ggacggttgg atgatcaggt gaaaatccgc
     9901 ggctaccgga ttgagccggg agaaattgaa gcggcactaa gaagtataga aggtgtaaga
     9961 gaggcggccg ttaccgtacg gacagacagc ggcgagccgg aattatgcgc ttatgtagaa
    10021 gggctccaaa gaaacgaagt ccgagcgcag cttgagagcc tgttgccggg ctacatggtc
    10081 ccagcctata tgatagaaat ggaacagtgg ccggttacac caagcggaaa gctcgaccga
    10141 aacgccctgc cagctcctgg cggagcggca gatgcggaga cctacacggc gccgagaaac
    10201 gtgactgaga tgaagctttc tcagct
//
