LOCUS       gnlProkkaONOMJNGG_18   15400 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ONOMJNGG_18.
ACCESSION   gnlProkkaONOMJNGG_18
VERSION     gnlProkkaONOMJNGG_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:41:26
            Original ID  :: gnl|Prokka|ONOMJNGG_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15400
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15400
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8330:10755]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8331..10755
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..15400
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15400
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             891..2117
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.4; E-value: 8.6e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.2e-10, bitscore:
                     31.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEEVVMKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEK
                     VDGVIISGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFF
                     QHQGLHLSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYIL
                     EDMEKAFDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFD
                     YVALGHIHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLE
                     VKRPIVALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTD
                     IVEITFSRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESV
                     FEEIERSRQ"
     CDS             2114..5293
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 498.3; E-value: 8.1e-151)"
                     /gene_kind="other"
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDHFQKSLEERLRQSNKDMEKRQAQLDGHFASQVWSE
                     EELSVLEQTPASEKLTRLEEFLSQRQENVTKQKSILKAAHEDLAQLQKSLQTAQDLAKI
                     FQELEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     EIAQEALSEKQQAFEDVKAKKEELTVQSKDFLQKEEELETWKENIIYAQSLAQEQEKIK
                     RSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLESLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLMIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVTKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIRKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             complement(5362..5490)
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MMTKKSVRTFLRVGRIKYVIQTISFLTILHKVVVNATTFFLC"
     CDS             5573..6037
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MKSLSISSSFFSISTSSTPQLTANSIGQHSTAKQSRKEIELAAAK
                     LVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTSQNDAM
                     NQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTN"
     CDS             6215..6346
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MNIEECKQISILDVANRLGISFKQVYDKAVYWIYSGVKGQYEY"
     CDS             6358..6516
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             6695..7261
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             7279..8091
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.8; E-value: 2.9e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIFTEHKGNYG
                     YRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAENLIQRQFE
                     ASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQVKAMLEQAF
                     TEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESFFGILKSEM
                     FYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             8331..9191
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_9"
                     /sec_met_domain="TIGR01716 (E-value: 1.3e-51, bitscore:
                     165.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     ILASS"
     CDS             9436..10755
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_10"
                     /sec_met_domain="Streptide_RRE (E-value: 2.6e-25, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.2e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.6e-14, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             10752..11843
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             11937..12539
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_12"
                     /sec_met_domain="TIGR04085 (E-value: 3e-16, bitscore: 49.8,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 8.9e-14, bitscore: 41.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERISKGE
                     FKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGVRAC
                     SINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKCSECP
                     LPWCGGGCRCSALKLDGTLLGSDLACFYEQKGGGVVV"
     CDS             12855..13766
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             13939..14199
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MRLSLAISYRKVPILFPITDPKIGIGITACPNIEDNALTDTSTHN
                     ICEFSKNSSFVIKFLRNLYASLAIPNEAVHNELATAAGVAV"
     CDS             complement(14325..14594)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MQWKEVNQFFETESIKLSDIEPSKVSYREVQRNQINTTIYNEKGN
                     IKDIDTSIIRDMYDKSKPTLKQGAYISAIAASLEGGYCIYNSNN"
     CDS             complement(15094..15207)
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MPTKIWLKPEQLDLYIKHLERFRDLYSKLDCSGIVNL"
ORIGIN
        1 tatgagtctt tctaaaatga tggtttagtc gcttttcatt ataggtcata tgggactttt
       61 tttctacaat caaaaaggct ccataatctc catagaggat ttacccacta cagaaattat
      121 agagcctgtt ttaaaggaga ttaaatcatt agtgtgttag tatcttccaa aaatctacaa
      181 gcgttactga ttagcactcc aacacattat aaatatattt caagtgattt aagataggaa
      241 ttagctatta ccggtgtttc tctaaaagaa ataaaaatca taccattcgt tcagatggaa
      301 taatgcatgt gacttataaa aaatctcaag tagggaaata gtaaatacta catgcctagt
      361 tccaagtcag ctaacaagct acggataaaa aaagcctaga ataaagtaaa aagtcaggag
      421 cccttagggt tcggattatt tttaggtttt catagtgaaa aatttaaaaa ggatcggtac
      481 tgacaataac gaaaagtgag taaatattat tgcctaaaat acaagatgtg cactagtacc
      541 aacctatatg ataatgctta gaatctataa aagtcaatta aaagaataga taatattgat
      601 tttcttggtt agaggtattt aaattactta accaattgag gcagggtaat ctagactata
      661 ttgattacta caacaacaaa tgcattaagg taaaactaaa aggactcaat cctgtgcaat
      721 acagagctaa atcctttgct tacataaatt gtctaacttt ttggggtcag tacaggatag
      781 cttgggagag attttttgat ctttacagct aaaaaacggg aaaactatca aagcctgtga
      841 aacttttaag cagtatttag cttgataagg tacaatagaa gtaagacaaa atgaatgagg
      901 aggttgtcat gaagttttta catacgtcag attggcatgt aggacgaacc ctcaatggct
      961 ggtctttgtt ggaggagcag gagtgggctt ttcaacaaat tgtggatttg gctattagcg
     1021 aaaaagtgga tggggttatc atttctgggg acctctatga ccgtgcggtg ccccctgtgg
     1081 atgcgattaa gctttttaat aagaccttgg cccgcttggt actggaggag cagattcctg
     1141 tctatgcgat tagtggtaat cacgatgggg ctgaacgttt acattttggg cgtgacttct
     1201 ttcaacatca gggccttcat ttaagtacac gtttggagga ggcttttgag cccattgagt
     1261 tggagaattg ccagattttt ctgctgcctt ttatcgatcc tattgatgct cgtatttact
     1321 ataaggatga tgagggaaag gaaattcagg ggattggtga tgccttgacc tacattcttg
     1381 aggatatgga aaaagctttt gatcctgaca aagctcatgt cttggtgacg cattttgcgg
     1441 tttctaagaa ggatgatagc gatggtcagg gtcttcgaga attgatgttg tctgaaacca
     1501 gtaatacggt aggtggtctt accaatgtga ccagtgacct tttcaagtct ttcgattatg
     1561 ttgccttagg gcatatccat acgcgttttg ctagtcctac caagcgcgtg caatattcag
     1621 gcagtccagt cgcctttaat gtcaaagaag ccaagcgtaa ggaagaaaag ggtgtctata
     1681 ttcttgaatt ggatgcgtct ggtgatatgt ctcagacctt ccatactcta gaggttaaac
     1741 ggccgattgt ggctttacag gaatcttttg aaaccttgat gtcacctgaa ttttataaga
     1801 atcaaccttg tcaaaaagcc tggttcgcct ttgatattca actgtctagt cgtaaggaat
     1861 tagagggtat caatgtgcgt gcccgactgg aagagattta tgggacagac attgtagaaa
     1921 ttactttcag tcgtctgggt gatgttaggg aagaaaactt gaccgttgat cagcacttaa
     1981 aagatttgga aatgcagtcg ccccaggaaa tcgtatttga tttttaccag acagtaactg
     2041 ggggcgatgt cttatctgag agacagactg cccttgtgga aagtgttttt gaggagattg
     2101 agaggagtcg acaatgagac cagtccagtt agaattgacc aattttggac catatcgtaa
     2161 ggaagttatt aatttcactc agtttgacca tgctcccctc tttttgattg gaggggatac
     2221 aggggctggt aagagtactc tctttgatgc catgacggta gccttgtttg ctacgaccag
     2281 tggtgatcgt aatgttgagg agatgcggtc aactttcgct ggtccagagg atgatttgac
     2341 caaggtgact ttctatttcc aacaaggcaa tcacctttat cgcattgacc gagttctcca
     2401 gcaagagagg gccaagcagg gtgggggcac taccatgcaa aaggcgacgg cttctctagt
     2461 cattgtggat aagattggtg gtcaggaaat tgaaaagctt ggggataaga tcaaggaagt
     2521 gagtgaccag attgagcaga ttttggggct caatgctgag cagttcaaac agattattct
     2581 ccttccacaa aatgatttca gccgtttctt gaaagaagat tctaagacca agactcaaat
     2641 tttaaagaaa atctttggaa cgggtatttt tgaccatttt caaaagagct tggaagagcg
     2701 tcttcgtcag agtaataagg atatggaaaa gcgtcaggct cagctagatg gtcattttgc
     2761 cagtcaggtt tggtctgagg aagaattatc cgtcttggag caaacgccag cctctgaaaa
     2821 attgacacgt cttgaagagt ttttgtctca gcgtcaagaa aatgttacga agcaaaaaag
     2881 tatcttgaag gctgcccacg aggatttggc acaactgcag aagagcttgc aaactgccca
     2941 agatttggca aagatttttc aagaattgga gcaagccaag gaacgttacc gtctggaaat
     3001 tgaggagggg gctcaaggac aggcagaggc aaaagtgcat ctggaggaat tacagtttgc
     3061 tcaaggtctg caggaaacca ttcggacctt gaagcagtat cggaaacagt tgatgcaatt
     3121 agagcaggac cttgaaattg ctcaagaagc cttaagtgaa aagcaacagg cgtttgagga
     3181 tgttaaggct aaaaaagagg aactcacagt tcaatctaag gattttcttc aaaaagaaga
     3241 ggagcttgaa acttggaaag agaatattat ctatgcccag agtcttgccc aagaacagga
     3301 gaaaatcaaa cgttcaacga ctaactacaa gcagttggaa gagacctatc agcaggctag
     3361 aaaagaggtt gagatgctta acaagtcctt gtctgacttg gaggctaatc gtcttagttt
     3421 agagagttta catgaggccg aaaaactctt ccagattgtg ggctacagtg tggagaatca
     3481 acttgctcag gacctgaaag agatagagaa cttgaatcag gagttgacaa agaccgaaaa
     3541 acgtcatcaa acgttatctt ttgatattga tcaagctcaa gaaattctca aagaattgga
     3601 agaggagtta agaaggactt tggtttcacg ccgtcaactc atgattgtcc aactgcaggc
     3661 agagttagag gaggggcatc cttgtatggt ttgtggtgct ctggaacacc ctaatgttgg
     3721 tggagcacag gctgatgaag tggccttgaa aaatctcatg gatcaggtgg agaagcttca
     3781 agctcaaaaa gaaaagcaag tcgctacttt atcaaatcgt caggctacct tgagtgaagt
     3841 tgcatctaaa cgtcaggatt tgcttgacca agtgactaaa gtcaaggcaa ctcttgaaaa
     3901 gcactatcaa gaattagaag agcacgttaa gggacggttt gattttgatt tttcgataga
     3961 ctatgaaact gaccgtgggc aagccctact cctgaaggtt gagcagtatt atcaagagtt
     4021 acaaaaacgt tatgataagg aagagacaga ttatatccga tatcaagatg agctaggtaa
     4081 ggctcaaaaa aaagcgacag atttggctaa aacctatcaa gaggccaagg cagtgcttga
     4141 ccaagctcaa gaacgcctag aggacttgca ggaagctcat ccagaacttg agtctgttga
     4201 ggtatatcaa gaacggattt cccttgctca tcaggagctg aacctctaca ataagcaagt
     4261 caaggaaaat agcgaagcct acaaccaact tcatgccgac attaaaggaa tcaaggggca
     4321 gattgagagt ataactaagt ctaaagataa ggtaaatcaa gatgttaagc gattatctgc
     4381 tgaattagag caaagtctca aggctgaagg agccctcgcc aatgacttag agcaggtcga
     4441 actctggctt attgaggtaa ataatcaagc tattcctatg cttcaggcca aattaacgac
     4501 ctatgcaacg ctcaaacaag aattacaggc gcagattcgt aaggggcaag agcttctcca
     4561 aaatcaagaa caaccagatc tcgatagtct agcgcaagca gtacagaatt gtcaggaaat
     4621 ctatgatagg cagctcgctc agttttctgt catggaaaag ggacttaagg atgcgacggc
     4681 tacctaccaa gcggctaaaa cccttcaaga cagcaaccaa gaggccttta aggcccacca
     4741 agaactcagt gatttggtta aggtggttaa gggagaaaat actgctctaa ctggtcgtct
     4801 taatcttgag gtctacgtta tccgtcagta tttccaacaa atcttggact atgccaatgc
     4861 taactacatc ggactattaa cggataaccg ctattccttt gttctaagtg aggaaggacg
     4921 cagggcgcgt gatcacttcg gtttggatat caacgtctat gaccagctga caggtagtga
     4981 acgctccgtt aaatccttgt ctggtggtga aacctttatc gctgcactgg ccattgccct
     5041 atccctctca gaagttgtcc aaaataccag caagggtgcc gttgttgaag cactcttcat
     5101 cgacgaaggt ttcggttcac ttgataagga agccctcact aaggctatct ctgtcctaga
     5161 acaaatcggt gaaaatcgca tggtcggtgt catcagccac gtggacgata tgaaagaagg
     5221 tattgctcag caactagtta tcatcaagtc gcacgatggc agtagccgta ttaaaattgt
     5281 ggataagggg taggaggaat cagtttatat aatactctat atcagataat cgcagttgta
     5341 gccatgtcaa atttgttcta atcaacatag aaaaaaggta gttgcattaa caactacctt
     5401 atgtagaatt gttaaaaagc tgatggtttg tataacatat ttaattcgtc ctactcgtaa
     5461 aaaagtgcgg acggattttt ttgtcatcat atttgacaat gttatagcaa aaactaatca
     5521 aggtaatatg aggctaccta atgtctccct aattcgttga acttttagct aggtgaagtc
     5581 attatcaatt tcctcctcat tttttagtat atccacctca tcaacaccac aacttactgc
     5641 taattctatt ggtcaacatt ctactgccaa acaaagtcga aaagaaatcg aattggctgc
     5701 agctaaactt gtagaggaca aacaagcaga agataaagca agtattttat catcagatac
     5761 tgtaaaagaa tttttgacac agtactatac gaaagaaaaa ctaggggaaa ataatacacg
     5821 tattcaacct tatatgactg aatcggccta ttctcaagaa ttgacaagtc aaaatgatgc
     5881 catgaaccaa gtgtataagg actatatttt ggattatcat tttgaaaaag cagatatctt
     5941 tgtcaatcag actacgaatc aagccattgc catggtctct tataatgtaa cttatgtatc
     6001 tgatttaaag aatgccaacc aatcaaagac aaactaaaca gaaaccagaa cggttaattt
     6061 gaactattcg aaactacctg gtaagttatt ggtcaaccaa gtacaggttt ggaaatctgg
     6121 gttagatgat ctagataagg caactcctaa aactttagaa gaatcctcat ctgttccatc
     6181 attgccgaat actacgacaa aatgatgata ttttatgaat atagaggaat gtaagcaaat
     6241 ttcaattctt gatgtagcca atcgattagg tatctccttt aaacaagttt atgataaagc
     6301 agtttactgg atctatagtg gtgttaaagg acaatatgaa tattagaagg agaaaaaatg
     6361 actaaacata gttatgttgc gaaatttaag cgtaaagacg aaaccgtctt tacgaaaagg
     6421 tttctagctt cagatttatt tgaggctgtt gaacatgcgc tagagtatgc cactaagcga
     6481 gatattctct atctcgactt agggcatgca ggatagtagt cagtagaaag tagaggctgg
     6541 gacaaaaagt tctcagtcac aaaaaagcta gagatttcca attgtggaac tctagctttt
     6601 taaattcgag tcactctctt gttatatttc agaagatttt tggtcaattc tatttcacca
     6661 agtctatcac aatcatgcaa aaagcaacgg ttttatgaac tgcaccccaa aagttagaca
     6721 gaaaaaatct aactttcggg gtgtttttat tatgaaattg acttatgaag ataaggttca
     6781 aatctatgaa cttagaaacc aaggatatag cttagatcag ctttcaaata aatttgggat
     6841 aaacatttct aatcttagct acatgattaa attgattgat cgatacggaa tagaaatcgc
     6901 taaaaaagga aagaatcgtt actactctcc tgaattaaaa caagaaatga ttgataaagt
     6961 cctatataaa ggctattctc aagatagagt ttctcttgaa tatgctctcc caaatcgtgg
     7021 gacgcttcct aactggctcg cacactataa gaaaaacggg tatactattg ttgagaaaac
     7081 aagaggaagg ttatctaaaa tgggacgtaa gccaaagaaa aaactggaag aaatggaacg
     7141 tcttcaagca gaaaatgagt accttagagc ggagaatgca gttcttaaaa agttgagaga
     7201 actccgattg agggaagaaa aagagcaaga agaaaaacgg aaattgtccg aggattggta
     7261 actgagtttt ctttagatat gcttctaaag attattaagc ttgctcgttc aacctattat
     7321 taccacttaa aacagctgga tcaaaatgat aaggattatg acattaaagc tgaaattcaa
     7381 gccattttta ctgagcataa aggaaattac ggctatcgtc gaatgactct tgaattgaga
     7441 aatcgaggaa ttgtgattaa tcataagaga gttcaacgtc ttatgaaagt acttggttta
     7501 accgctagaa ttcgccgtaa acgtaagtat tcttcatatc aaggagaggt tggtatgaaa
     7561 gcagagaatc tcatccaacg ccagttcgaa gcatccaaac cattggaaaa atgctacaca
     7621 gatgtaacag aatttgccat tccagcaagc agccaaaaac tctatttgtc gccaatttta
     7681 gatggcttca atagtgaaat tatcgcctac aatctttcta agtcaccgaa cttgatacaa
     7741 gtgaaagcta tgttagaaca agcctttaca gagaaacatt acaaaaatac aattctccat
     7801 agtgaccagg gatggcaata tcaacatgat ttctatcatc attttttaga ggagaaagga
     7861 atccaaccat ccatgtcacg taaaggcaat agtccagaca acggcatgat ggaatccttc
     7921 tttggcattc ttaagtctga gatgttttat ggttatgaga agacgtttaa gtcaattgag
     7981 catttggaac aagcaattgc agactatatt aattattaca acaacaaacg cattaaggta
     8041 aaactaaaag gactcagtcc tgtacaatac agaactaaat cctttactta aattatttgt
     8101 ctaacttttt ggggtcagta cattatgccg ttgctttttg gagctaaagg acttttgtcc
     8161 cagactcttt atcccacgac gataacgata atgccttcaa atacgacaag aagaagtgtt
     8221 agtaaaattt gctttttcat gtgataatcc tcacttttgt ttttctttat tgtatgatat
     8281 gatgaaagca aatgaaaatt attcccatat atgcgtgatg gaggtgtagt atgaaaaaat
     8341 ttggagaaat ttttaaaaag tttcgagaat cgagaggatt acgattaaaa gacgtcgcaa
     8401 aggctggtat atcaacgtct cagctctctc gatttgagaa aggagaaaca gatttaacga
     8461 tttcaaagtt catgtttatt ttagatgaaa tcaatatgcc aatagatgaa tttatgtatg
     8521 cggtccatga ttttcataga gatgagttaa acgaactgtt atcgaaagta cgtcattttg
     8581 tgtcaacacg tgacgtagaa ggtatgaaaa aattacttta ttctcagatg gaactggaag
     8641 ataggcgaga aaaatttcat caaatcaata ttattttatt gaaaattcgt ctacaggatt
     8701 tatcaggaga aacttactat acaaaggatg atttgacata tttaacagat tatctcttta
     8761 gtgtagaata ctgggggtac tatgagttat tgattttctc gaatacttta gatgtattaa
     8821 atcatgatgt tttcatggtc ttagcaagag aaatgtttag gcgttctgat ttttacaaag
     8881 aaattccaaa taacagacga ttaatttcaa cgatgctttt aaatggatat attacatgtg
     8941 ttgaaagaga aaaatttatg gatgctttat attttgaaaa gcagctaaat caatgctttt
     9001 ttattgagac agaagtatat gaacgtttag tctttaagta tgcacaaaat ctttatcaat
     9061 ataaagagga tggaaatgtg aaagcaatta ttgaaatgaa gaagtgtgtt ggagcgatga
     9121 aattagcagg aagtcatcac ttagcaaaga cttatgaagg acatttagaa aaaattttag
     9181 ctagtagtta gaaaatgcaa atatgggaat attttattgt aagtgttgaa aagaaatata
     9241 atcacagtat catattcgaa aggagtacca aatatgtcta aagagcttga aaaagtcctt
     9301 gagtctagtt caatggcaaa aggtgacggc tggaaggtga tggcaaaagg tgacggctgg
     9361 gagtgataaa gtaatttatc ccataagtta agcagaggct atattttcct ctgctttttt
     9421 agaaaggtat tcaatatgat gacaatttca gaagattttt tatttagact agaaaagttt
     9481 ggtggaattt tgataaataa agtaactttt gaccgaattg agttagatga gagtgaagct
     9541 tattttcttt atttggttca aaatcatggt tttgaaattg ctacgtcctt ttttaagaaa
     9601 gaaataaaag cagggaaact agagcgagta ctcttattaa atatctattc tgataataat
     9661 attgagggat catcgaaaaa tcctgacgag actcttcaaa atgcgagaaa gcatgtagca
     9721 aaattaaaaa aacataacat attgagtttt ccgcttgaac tagtaatata ccccagtatg
     9781 tactgtgatt taaaatgtgg tttttgtttt ttagcaaatc gtgaagatag aaatgccaaa
     9841 cctgctaaag attgggaaag aattttgcgc caagcaaaag ataatggagt gttaagtgtt
     9901 tcaattttag gaggggaacc gactagatat tttgatattg ataatttgtt gatagcttgt
     9961 gaagaactga agataaagac tactataaca actaatgccc aattaataaa gaaaagtaca
    10021 gtggaaattc tagctaaatc taaatatatt acaccggttt tatctttgca gactttagat
    10081 cctaaattaa attttgaatt aatgggggtg agacctgata gacaaattaa attagcgaag
    10141 tactttaaag aggttggaaa aaaatgtaga attaatgcag tgtatacaaa gcaaagctat
    10201 gagcagatta tagaattggt tgatttttgt atagagaata aaatagatag attttcagta
    10261 gctaattatt ctgaggtaac aggatatacg aaaataaaga aaaaatacga tttagctgat
    10321 ttgagaaggt tgaatgagta tgttacagat tatataactc aacgggaagc taatttaaat
    10381 tttgctactg agggatgtca tcttttcacc gcttatccgg agttgataaa taattcaatt
    10441 gaattttcag agtttggcga aatgtattat ggatgtcgtg caaaatatac taagatggaa
    10501 ataatgtcta atggggatat cttgccttgc attgcttttt taggagttaa tcaaactaag
    10561 cagaatgcct ttgaaaaaga tttgttagat gtttggtatg atgatccgtt gtatggaggg
    10621 attcgttctt ttagaacgaa gaattctaag tgtttatctt gtggattgtt aaaaatttgc
    10681 gagggtggct gctatgttaa cttgattaag gagaagagtc caaaatattt tagagaccca
    10741 gtttgtaact tatgagtaag aagattttta atttatacgg aatgaatatg tttctatctg
    10801 gattaccgta ctactttgta ggaattttac tattaaagca cttaggtttt tcgttcacag
    10861 aaatagctac tttatcagtt attactgagc tatgtggctc agtttttgat attcctttaa
    10921 gttatatttc aagtaagatt ggttacaaga aaattttggc tatttcaaat ttattattaa
    10981 ttttagcatt atggggccta ttgtttggaa aatcaaatat aatatatatt tcagcgatat
    11041 tttttggatt gtcagaatca ttatcttcag gagttcttat ttcttataat tttgaaataa
    11101 ttgatgacga agttgtatat aaatcatttt tgaaaaatct caacacatta aaatatattt
    11161 ttattgctat tattacgatt atatctccac ctttattgca taggaattat atttatccta
    11221 ttattatatc cattgtattt gtaattttca gtttattata tttaatagga ttacccgaga
    11281 ttaaaaagga acaaaataat aaacaaaaat tttttagcct cgataatatt caaaatattc
    11341 catggttatt aataatatta ggagtagcat tctcaactct aattatgatt agcaattctt
    11401 atgcagggat attcttaaat gaacagggac tttcactaga tatgctggga attatactat
    11461 ttatgtttaa tatatctatg gctttgggga gttatctaaa aattaagttt gaagtaagct
    11521 tgatgttacc agtattagct atactcatgt tttttcaaac taatctaatc atccaaatta
    11581 taatcctttt attaatgcgt gttcttaatt ccaactacaa taatcatttt tattataaat
    11641 ttaatatgtc aatagaaaaa aatagagcag tatcatggtc agtatataat ttgtttattt
    11701 cgattagttt tatgttagct gatttcctag ctggtatttt tgctgataac tttagtatta
    11761 ggagcaatta tttaatattt ggtatagtag ctctttgttg cttagtatct tattcatttt
    11821 ctaacagaga gaaaagaact taaaagttgt atttctaatt catttgccaa attattgata
    11881 gcacaattgt ttgcaaattt agcagatatt ttctttagag tataagattg aatgatatgc
    11941 ttggtattga gtatatgtca gttatggtta tttgtcctac tggtagggct aatgacggta
    12001 gtattttagc agataaaaaa caatggtatc ctgtttttct tgatttaaca gagcggattt
    12061 ctaaaggaga gttcaaagtt aaatttaaaa ttgttcctcc taatgaaagt gatgtttttt
    12121 tgacacatta ttttccgctt gcattttata atagatcaga tttattagaa aatgtttggc
    12181 atcaaaaagt agatataaat tttgataagc caagggaaat atcttgtcaa gctggagtta
    12241 gagcatgttc aattaatcat aaaggagatg tatacgggtg tgacttgatg aatggtatag
    12301 atgaattagt tgctggaaat gttaaagaac aaaagtttag cgaaatttgg caccattctg
    12361 ctgtatttaa taaactaaga tcaattacat ttgatgatat ttctgggaaa tgttcagaat
    12421 gtcccctacc atggtgtggt gggggatgtc gatgcagtgc cttgaaatta gatggaacgt
    12481 tactgggctc tgatttagcc tgcttttatg aacaaaaagg aggtggagta gtcgtatgaa
    12541 agaacatttt gtgataagag gtaagagaga tttcattgta aataaagtag cagatgaata
    12601 cataggatac gatctacttg attagagtac tattcatttg atgaaatagg agcagaaata
    12661 ctttattgca tttctaaaaa tttttcttta gacaagattg tagaactatt acagcaagat
    12721 tatgaggtat ctgctaatga ttgtaagcag gcaattattt catttttaga agaaactcct
    12781 attttgcata ttatttatgc aaatttagtt aaatctgatc tttacttaca tttgaagcct
    12841 tttagagagg aaaaatgata gattcaaaag aaattaacaa atttgccttt cccttagttt
    12901 taacaaatat tggtcaagta attattgggc agatagcatt gcattttgct gtgaacaatt
    12961 cctcaattgc tctgtcagga atttccatta ttcagaatct cttatttgct tttggtggac
    13021 ttttaggagc attcagtttg tcatttaata ttaaaagctc taaggcgtac tctaatcggc
    13081 aaactaacag gtttgatgat ttattgaaat caaatctaac cttagattta attatcggag
    13141 ttgcctttgc ggtttttgtc attatttttg gaaatgtaat cttgaagcag ctctatggat
    13201 ttaaagggca actattgtcc ttatccacca tttatttagt cttcatgtct ccatatatcg
    13261 gattgacatt attaaacttt tcgctgacaa atttattaag agttcaaaag aaaacaaaac
    13321 caattatgtg ggttggactt atcagttcat taatagatgt tgtgttaaat tatgtactgg
    13381 taccacaaat cggaattaag ggagcagcca tatcaacgat tgtatcctta gctttcatat
    13441 cgcttagtta cttgtttatg gtttatccaa tgattttgaa ggctttatcc attacatcta
    13501 caactaaatt tgaattaata acatttggta ttcctttggt tggtcaagaa attctggaga
    13561 gtgttttgtt tattatggtg tttgatgcct tgatgtcgag attaggagta gaattgttgg
    13621 ctatttatgc agttattagt caattgcttt caattgtgag tgtaccttct tttgtttatt
    13681 cgacaaccgt ttctatctat ttacctgaag cagagaaaat aggagaggtt aacgtatttt
    13741 taaaaaacat atttaaaaat tcataagatc cctgaaaagc gatattatag tcaggagaaa
    13801 atgccttccc taaaagttta tagtaattct taatctctct gaagttgatg attatataat
    13861 tcaaattaat tatctaaaaa atagttatat tcttgtatct ctttgaaata atctgctatc
    13921 agtaatttct ctttcattgt gagattatct ttagcgattt catataggaa agttcctata
    13981 ttatttccaa taacggatcc taaaataggt attggaatta cagcatgtcc taatattgag
    14041 gataatgcac taactgatac ttcaacacat aatatttgcg aatttagtaa aaattcttct
    14101 tttgtgatta agtttttacg gaatttgtat gcttctttag cgataccaaa tgaagcagtg
    14161 cacaatgaac ttgctactgc tgcaggagta gctgtgtaat tcgttagggc gtatatcgta
    14221 atgcctcgag tacttccttt tatagctcca attccactat ctttagaaat ttcaagacaa
    14281 tcgtcttttg taaactcact aatagttttc cctaagcgct ttttttaatt attgctgtta
    14341 taaatgcagt accccccttc tagagaagct gctatagcgg atatataggc tccctgtttt
    14401 aaagtaggtt tgcttttatc gtacatatct cttataatgc tagtatcaat atcctttata
    14461 ttaccttttt cattataaat agtggtattg atttgattcc tttgtacctc cctataacta
    14521 actttcgaag gctctatatc agaaagtttg atgctttctg tttcgaagaa ttgatttact
    14581 tctttccatt gcactcatgg tagatatctc gaatagtatt aagaatagct ttcttttgac
    14641 gatgatagtt agtccttgtc tttttaagat aattataata agcattggga tgaatattca
    14701 tatgcaagaa caaccaacgc aaaccaaaat cttctttata gttatcaata aaacgatatg
    14761 cctctaatcg atttcctttg caaagaatgc cgctgctttt tttaagaaat cattttcctt
    14821 ttcaagctct gccttttctt gacgtaattt acgaacctcc tccatgagtt caagctgtga
    14881 tttttcttta ttattagttt ggcattcttt gcgataatgt cttacccaat tagagattga
    14941 ggcttgggat acgccatatt cagcagctaa gctttttaat gttcatccgt cttgaatgtg
    15001 cagtcgaaca attttttatc gtgtttcgtc tggatagtgt ttcatgttat gtctcctatt
    15061 ctaatgaata gtttaactta ttaggtagga gtgttacaaa tttactatac cagaacagtc
    15121 tagtttacta tataagtctc taaatcgttc taaatgttta atatacaaat ctaattgttc
    15181 tggttttaac catattttcg ttggcataat tttttctctt ttcctaataa ataaaaaaga
    15241 tagcacaaat atttccttgt gctatctcaa catttagtta ataatatatt ccttagtcat
    15301 aattatattt ttgctgattt ttagtcataa attaaattac ttctccagga ttgtcatttt
    15361 accgtcaatt atctgataaa ctttgtctgc catatctttt
//
