LOCUS       gnlProkkaDLNOEJAJ_20   16785 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DLNOEJAJ_20.
ACCESSION   gnlProkkaDLNOEJAJ_20
VERSION     gnlProkkaDLNOEJAJ_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:43:45
            Original ID  :: gnl|Prokka|DLNOEJAJ_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16785
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16785
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2763:16783]"
                     /cutoff="20000"
                     /detection_rule="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /neighbourhood="20000"
                     /product="transAT-PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2764..16783
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /neighbourhood="20000"
                     /product="transAT-PKS"
                     /protocluster_number="1"
     cand_cluster    1..16785
                     /SMILES="C(C)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(PKS_AT and not (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and
                     (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
                     or cds(tra_KS and PP-binding)))"
                     /kind="single"
                     /product="transAT-PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16785
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="transAT-PKS"
                     /region_number="1"
                     /rules="(cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or
                     ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or
                     cds(tra_KS and PP-binding)))"
                     /tool="antismash"
     CDS             1625..1810
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MKLYTRFIFYITNNFLFIRLPVCGIIIPMLSQSIRIFEFFDISYL
                     HLEELLVNFNCKWNYK"
     CDS             2083..2640
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MSWYVLYVETGQEEIVKCLINKYFADLTIEVIVPKRKIREKRQGK
                     LYEVSRLLFPGYVFLNTYMNIDIYYGLKKIPRCFRLLNSYKYKTDYLVDDVSHNITSVF
                     CTIEQGEIAPILQLLQQNETIGFSQIYKEDSEITVISGPLKGLEGIIKKIDKRKNRAKI
                     ELNFMGVIKLVDVGVEVLTRDS"
     CDS             2764..3747
                     /NRPS_PKS="Domain: PKS_AT (16-301). E-value: 7.8e-67.
                     Score: 217.6. Matches aSDomain:
                     nrpspksdomains_ctg18_3_PKS_AT.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 197.6; E-value: 6.8e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-67, bitscore: 217.6,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIVRCDEVMKEKIIFMFSGQGSQYFKMGKELYEYESIFSKDMGQ
                     LDAVFQKATGKSIINYIYNEHRLKSDIFSDLFYTHPAIFITEVALARLLVSKGIRPHAV
                     IGSSMGEYAAAVVADVFQPEEFLNILIEQVKLLNEFSSPGGMMAILDTHKIYDEVPILH
                     HHANLAAINNESHFVISANQEGIKTVERYLRLKEITYHKLPVTIPFHSEHIELASEAVQ
                     ESLSQISFKSPCLPFYSSVSGKKLEHLTAEYFWNVLKKPIHFIRALTEAVDHGGTILID
                     LGPSGTLANLAKAHFRNRTDISIFSILSPYTDNVRALESVYTKSVQ"
     aSDomain        2812..3666
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_3_PKS_AT.1"
                     /evalue="7.80E-67"
                     /label="ctg18_3_PKS_AT.1"
                     /locus_tag="ctg18_3"
                     /protein_end="301"
                     /protein_start="16"
                     /score="217.6"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFSGQGSQYFKMGKELYEYESIFSKDMGQLDAVFQKATGKSIINY
                     IYNEHRLKSDIFSDLFYTHPAIFITEVALARLLVSKGIRPHAVIGSSMGEYAAAVVADV
                     FQPEEFLNILIEQVKLLNEFSSPGGMMAILDTHKIYDEVPILHHHANLAAINNESHFVI
                     SANQEGIKTVERYLRLKEITYHKLPVTIPFHSEHIELASEAVQESLSQISFKSPCLPFY
                     SSVSGKKLEHLTAEYFWNVLKKPIHFIRALTEAVDHGGTILIDLGPSGTLANLAKAHFR
                     NRTD"
     CDS_motif       2815..2862
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_3_0001"
                     /evalue="7.20E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ctg18_3"
                     /protein_end="33"
                     /protein_start="17"
                     /score="21.4"
                     /tool="antismash"
                     /translation="FSGQGSQYFKMGKELY"
     CDS_motif       3055..3138
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_3_0002"
                     /evalue="1.10E-11"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg18_3"
                     /protein_end="125"
                     /protein_start="97"
                     /score="36.7"
                     /tool="antismash"
                     /translation="GIRPHAVIGSSMGEYAAAVVADVFQPEE"
     CDS             3790..5148
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 230.7; E-value: 4.5e-70)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MNKRIIQLAFPIFIESALVMVDGLIHIIWVGQLVGGKAVAAVGAC
                     FPIILAMSAIANGAAKLTSTPMLQRFLSKKNRDDVVQKQINVSWSFAIFIVLLVTVGIY
                     LAAQWILKMLGTPEGIIELAIGYLQIMAIGFTIMYFSFLITSLLRDVGYKFARMLFIVI
                     ATAGNLVLVPMWIIGIGPFPKLGLYGAVFASFIVSIIAIIVSVGYLLRHYKGLLIKPTK
                     LRWDRDILVSLLPVSIPVFLQQFLLALGYTCIIIFVNPFGIDATAAFYIISRIDSLVAL
                     PAIAVMIAMSILTKQLVQGEKLERIKSLFHSGLLINFPLTFLIALSCFLFPEWIIRIFI
                     TAPSIVTIGADYLKIISFGYLLFTLLYACNGIINGAGKGGITLVFSLASLLVIRVPAAA
                     ILTQAGFKVTGVWFAVLTSFIALAICSWLYYLSGLWRKKLDVKEMKTQRVMPS"
     CDS             5233..5901
                     /NRPS_PKS="Domain: oMT (44-151). E-value: 5e-13. Score:
                     39.7. Matches aSDomain: nrpspksdomains_ctg18_5_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 98.8; E-value:
                     5.7e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MSENPTKSYKGPGMNGVIGTWYAKNTQKKIEKYTRDAKKVLKALS
                     DGDSVLELAPGPGYLSIELAKLGNFQIFGVDISDKFVHMAQNNAGKAGVDVDFRHGDAA
                     QIPFDDESFNLVVCRAAFKNFAQPVIALNEMKRVLKPGGKAVIIDFKGDVPKADINKFV
                     TDDMGFKGLNAMIIKWMFRNVVIKQAYTKEKFMAFVKESNFETCDLKEGLIGIEAWLER
                     "
     aSDomain        5365..5685
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_5_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="5.00E-13"
                     /label="ctg18_5_oMT.1"
                     /locus_tag="ctg18_5"
                     /protein_end="151"
                     /protein_start="44"
                     /score="39.7"
                     /tool="antismash"
                     /translation="SDGDSVLELAPGPGYLSIELAKLGNFQIFGVDISDKFVHMAQNNA
                     GKAGVDVDFRHGDAAQIPFDDESFNLVVCRAAFKNFAQPVIALNEMKRVLKPGGKAVII
                     DFK"
     CDS             6077..6856
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 63.1;
                     E-value: 3.6e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MYNENLPMLWTTRLAFKREEEQDFPSTCCLCYSDSFHDYLQTKSF
                     LHPKERVYFSQLQFNRRIKSYLAGRYAGKNAVSLLSGEEKLSAIAIEPGIFHQPVVHFP
                     GRSAIQVTISHCDDLGMALAYPDTCPLGVDIERLQADKQAVLAGQMTAEEHGLIQSLPF
                     SSVQSLTLFWTVKESLSKVLKTGFISPIDIFAIRTVEVAHPVVTSYFENFPQYCATSFF
                     FTSYVCSITHPKGVDWPKDSIYRLLSQVTPVLERINT"
     CDS             6887..9235
                     /NRPS_PKS="Domain: PKS_AT (16-294). E-value: 1e-55. Score:
                     181.1. Matches aSDomain: nrpspksdomains_ctg18_7_PKS_AT.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 431.1; E-value: 1.2e-130)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="PKS_AT (E-value: 2e-56, bitscore: 181.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILKTKKEGDKRMTVYVFPGQGSQKKGMGEGLFTEFPHLTKQADD
                     ILGYSIQTLCLENPEESLGKTQYTQPALFVVNAFHYLKRKKEANEKPNYLAGHSLGEYN
                     ALFAAGVFDFETGLKLVKKRGELMSQCYGGGMAAVVGLNEQEIAEVLAFNGLAQLDIAN
                     YNSPTQMVLSGSQEDITRAKGIFEQTPNVQLFVPLNTSGAFHSRYMQKVKSEFSDYLGE
                     FSFFAPAIPIISNVEARPYGENIKDNLIAQIDHPVKWTESIRYLMGKGETDYLELGPGH
                     VLTNLVNQIKRKASPLIVEDKPTLVIEEIEKTAEKAPSPDIPSRLTASSLGSDSFKKDY
                     NLKYAYLTGGMYRGISSTSLVVRVGKEGMMGFFGSGGLKLTEIEQAIVTIQKELCQGEP
                     YGFNLVHQFNHPQREEEIVNLFLKNGVTVIEASAFLGVTPALIIYRAKGLKPSADGSIG
                     CHNRIIAKISRPEVAEAFLSPAPERLLNKLEMEGGITSQEAKWLRQVPMADDITVEADS
                     GGHTDSGVSYALLPTIIRLRDRLVAKYAYKKEIRIGAAGGIGTPEAAAAAFTLGAAYIL
                     TGSVNQCTVEANTSDAVKDLLQQMNVQDTDYAPAGDLFELGSKIQVLKKGVFFPARANK
                     LWELYRHYESWEAIDEKTRHHIEELYFKCPYEEVYAKVKLHYSPEELQKIENNPKHKMA
                     AIFKWYFHYSNQLALSGNPEFKVDYQIHCGPALGSFNEWVKGTGLENWRNRHADYIGKY
                     LMDETAQLLTERFQQLLPVKESLAFQTIT"
     CDS_motif       6929..6982
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_7_0001"
                     /evalue="2.00E-07"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg18_7"
                     /protein_end="32"
                     /protein_start="14"
                     /score="23.0"
                     /tool="antismash"
                     /translation="VYVFPGQGSQKKGMGEGL"
     aSDomain        6935..7768
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_7_PKS_AT.1"
                     /evalue="1.00E-55"
                     /label="ctg18_7_PKS_AT.1"
                     /locus_tag="ctg18_7"
                     /protein_end="294"
                     /protein_start="16"
                     /score="181.1"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VFPGQGSQKKGMGEGLFTEFPHLTKQADDILGYSIQTLCLENPEE
                     SLGKTQYTQPALFVVNAFHYLKRKKEANEKPNYLAGHSLGEYNALFAAGVFDFETGLKL
                     VKKRGELMSQCYGGGMAAVVGLNEQEIAEVLAFNGLAQLDIANYNSPTQMVLSGSQEDI
                     TRAKGIFEQTPNVQLFVPLNTSGAFHSRYMQKVKSEFSDYLGEFSFFAPAIPIISNVEA
                     RPYGENIKDNLIAQIDHPVKWTESIRYLMGKGETDYLELGPGHVLTNLVNQIKRKA"
     CDS_motif       7157..7273
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_7_0002"
                     /evalue="5.80E-17"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg18_7"
                     /protein_end="129"
                     /protein_start="90"
                     /score="53.8"
                     /tool="antismash"
                     /translation="KPNYLAGHSLGEYNALFAAGVFDFETGLKLVKKRGELMS"
     CDS             9252..9506
                     /NRPS_PKS="Domain: PP-binding (15-73). E-value: 6e-09.
                     Score: 28.2. Matches aSDomain:
                     nrpspksdomains_ctg18_8_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_8"
                     /sec_met_domain="PP-binding (E-value: 1.2e-09, bitscore:
                     28.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKEDIFSILVQHTREIVPELEQHHFQWDDRLADLGANSVDRAEI
                     IMETLEALSLQIPRIELSEARNLGGLAEILYEKCSMHDL"
     aSDomain        9297..9470
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_8_PP-binding.1"
                     /evalue="6.00E-09"
                     /label="ctg18_8_PP-binding.1"
                     /locus_tag="ctg18_8"
                     /protein_end="73"
                     /protein_start="15"
                     /score="28.2"
                     /tool="antismash"
                     /translation="EIVPELEQHHFQWDDRLADLGANSVDRAEIIMETLEALSLQIPRI
                     ELSEARNLGGLAE"
     CDS             9478..10164
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     177.9; E-value: 2.8e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MKNAACMIYNLYSLKMSYHFFINYTYLIVEPNTRNAIVVDPAWEL
                     DRITQQLEKKHANLRAILLTHSHYDHVNLVPALSDLMQPDVFLSQKEIDASGFRCKRLN
                     AINDNDCLLLGELPFHCLLTPGHTMGSMCFQLDKSLFTGDTLFTEGCGVCPRPGGSPEA
                     MYLSIQRIKAEIEDDVRIFPGHSFGMSPGKTMGHLRKNNIYLQLNREHFIKFRMRKNQR
                     GIFDFQ"
     CDS             10180..10983
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 67;
                     E-value: 3.7e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_10"
                     /sec_met_domain="PF00561 (E-value: 1e-23, bitscore: 73.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-21, bitscore:
                     67.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGELEVIHANPTGMPKTPPLLFVHGANHAAWCWKENFLPFFQSHG
                     FQSYALSFRGHGHSEGRGNLHTFTMEDYVEDVYNVLETLEQKPIIIGHSMGGAVVQKVM
                     HQHPDRIEAAVLIASIPPGGMLKDFFRLLLMHPKKFRQLSLYNQGKTTVFPVDLFLSGE
                     TPEELQASLVGKLQPESTKASRDCLKRVVPKNTVAQVPLLVLGTDGDTMISKKTTQSIG
                     RFYQTEPVIFPKMCHDMMLDPDWRKVAEQILAFSLREEERMVDEA"
     CDS             10973..16783
                     /NRPS_PKS="Domain: PP-binding (13-79). E-value: 7.5e-12.
                     Score: 37.5. Matches aSDomain:
                     nrpspksdomains_ctg18_11_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (104-522). E-value:
                     1.1e-154. Score: 507.2. Matches aSDomain:
                     nrpspksdomains_ctg18_11_PKS_KS.1"
                     /NRPS_PKS="Domain: Trans-AT_docking (538-694). E-value:
                     1.8e-28. Score: 91.7. Matches aSDomain:
                     nrpspksdomains_ctg18_11_Trans-AT_docking.1"
                     /NRPS_PKS="Domain: cMT (847-1064). E-value: 4.8e-81. Score:
                     264.0. Matches aSDomain: nrpspksdomains_ctg18_11_cMT.1"
                     /NRPS_PKS="Domain: PKS_PP (1084-1162). E-value: 4.8e-13.
                     Score: 41.2. Matches aSDomain:
                     nrpspksdomains_ctg18_11_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (1210-1628).
                     E-value: 7.6e-165. Score: 540.7. Matches aSDomain:
                     nrpspksdomains_ctg18_11_PKS_KS.2"
                     /NRPS_PKS="Domain: Trans-AT_docking (1639-1793). E-value:
                     1.4e-33. Score: 108.2. Matches aSDomain:
                     nrpspksdomains_ctg18_11_Trans-AT_docking.2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: ATd"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS: tra_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047:phosphopantetheine-binding domain-containing
                     protein (Score: 36.3; E-value: 8.5e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="PP-binding (E-value: 1.5e-12, bitscore:
                     37.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 1.6e-171, bitscore:
                     560.3, seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ATd (E-value: 2.8e-34, bitscore: 108.2,
                     seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHDRRVRNPVKEKLVEEFIQVVGEQDQPIDLNKSFLELGMNSIK
                     AVDFVEAVNNSLGLELGVEVIFDFRGIPELAEHIAELYSAEEEKNPSPESALNSDSSMD
                     IAIIGISGKFADSENIEDLWSHLKAGECCIKEVRRRGWDEKTYYTPEAVQKNRSVSKWG
                     GMLSHIDQFDAGFFDISSEEAERMDPQQRLCLEESYKAFEDADYPAEKLAGKKVGVFIG
                     GRTSDYRKRLWKKMDTFNFWGNEMSMLASRLYYFFNFKGPSLTVDTACSSSLVAIHLAC
                     DSIRKGESEMALAGGVFIASTPEFFKMSSQAGLLSPDGQCKAFDPQANGMVLGEGVGVA
                     VLKRLDDAVRDQDHIYGVIKGSAINQAGRTNGMTAPSVTSQKELIQEVYTKSQINPETI
                     GYIEAHGTGTMLGDLMELKALSVAFKEITDKSQFCVVGSHKPNIGHATLASGMAGLFKI
                     LMAMKDQVLPPHRPTGQGQDHFLNSPFVFNTKLRQWKSHPDMPLRAGLNALGSNGTNAH
                     IIIEEWVEQSVQSISPIQKPYYLFLFSAKNIEALHQRLIDLADWLEHDGEQYSAEEVAY
                     TLSAARSHFDVRYAFIASGLMDLRHHLRKVIQEGFELGGLWHQRASTFQPASEKLNNGQ
                     QLIHTLSNGTVLHQDTYQEYVAKLSDLYIQGYDLDWTGLYHKNRKVPLPSYPFCKTSYW
                     TTEQEDTAVQEPAVFSSYGLQMRDMEELLVKLLLKQLQSLGILADQRMTLADMQKKLGM
                     SYIYRKWLARSLQFLVDKQWVVCDETDQYSLNPSIEKEQDAWEVWERQKQHWLATPDAR
                     MQTILVEHTLRSLPRILTGEVLATDIIFPNSSMELVEGIYQNNAVADYFNHLLAQKVID
                     YIQERLRQNPDARIRIIEIGAGTGGTSVRVLDHLKSYLGHLEDYCYTDISKAFLVYAEK
                     RFKADYPFVSYRVYNAEAEAAEQGISIDTYDIAIATNVLHATKNIMQTLRRVKAVLKAD
                     GLLILNEISDNSLFLHLTFGLLEGWWLFQDDTLRLPGGPAVSAEGWRRVLEQEGFKQVR
                     FPAVEDHTKGQQIIMAFSNGHVRQEAAQKQPAVTTKNHHIAAALKNWMAEHISHALSTE
                     AQAIDFRAAFRDYGVDSISGNNLVQVINQTFFLDLGTTILFDYSSIDQLTNFLLTHYKD
                     AIAAFFGKEKPPAEETTIGHLEERKEVLSTHETKQVSKGRQKGPIAIVGISGKFANSEN
                     VHALWEHLSKGTNLIDHTSRWRRPGDKDETVKSWEKGSFIEDIDQFDPFFFNISGVEAS
                     YMDPQQRLFLMASWQALEDAGYAGKSIEGRLCGVYAGCNSGDYHHLMNDYPSREVPQAF
                     WGNLASIIPARIAYYLNLQGPAIAVDTACSSSLVAMHLACQGLWTGEIEMALAGGVSIQ
                     CTPELYQAEHQAGMLSPTGQCYTFDDRANGFIPGEGVGVVVLKRLEDALADGDHIYGVV
                     RGSGINQDGTTNGITAPSLRSQVRLERAVYDQFGINPEEIQMIEAHGTGTKLGDPIEYQ
                     ALTQAFQHYTDEKSYCAIGSIKTNIGHAQLAAGIAGVIKILLALKHRKIPPSLHFEQGN
                     SNIQFKDSPFFVNTELKEWEVKPGAKRCAAVSSFGVSGTNAHMVIEEAPDVIRKHPVQP
                     GYLLVLSARSEEALRKQAQQLIDYSKENQEGVGDICYTLLVGRQHFKHRLSCVVRDQHD
                     MVAQLEEWIENKAISSVFTHTVHESEHREQPALKKFGNHCIRQSDVNEEEYMDNLSTVA
                     DLFVQGYELDYPALFANGQYSRVPLPTYPFAMERYWVPQPDADVAPAREATVKAAPTQP
                     QAAEEVAASTEEGQLMTFAESWQRQDLTDERMPLPSVWVCFLSNPAHQQALRTVLQTRY
                     PETEVIFVAQGTAERRESPHHYQLNREDGVAYRQTLQRIAADWGPGFALLYLWPLEDPA
                     VISD"
     aSDomain        11012..11209
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_PP-binding.1"
                     /evalue="7.50E-12"
                     /label="ctg18_11_PP-binding.1"
                     /locus_tag="ctg18_11"
                     /protein_end="79"
                     /protein_start="13"
                     /score="37.5"
                     /tool="antismash"
                     /translation="KLVEEFIQVVGEQDQPIDLNKSFLELGMNSIKAVDFVEAVNNSLG
                     LELGVEVIFDFRGIPELAEHI"
     aSDomain        11285..12538
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="1.10E-154"
                     /label="ctg18_11_PKS_KS.1"
                     /locus_tag="ctg18_11"
                     /protein_end="522"
                     /protein_start="104"
                     /score="507.2"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAIIGISGKFADSENIEDLWSHLKAGECCIKEVRRRGWDEKTYYT
                     PEAVQKNRSVSKWGGMLSHIDQFDAGFFDISSEEAERMDPQQRLCLEESYKAFEDADYP
                     AEKLAGKKVGVFIGGRTSDYRKRLWKKMDTFNFWGNEMSMLASRLYYFFNFKGPSLTVD
                     TACSSSLVAIHLACDSIRKGESEMALAGGVFIASTPEFFKMSSQAGLLSPDGQCKAFDP
                     QANGMVLGEGVGVAVLKRLDDAVRDQDHIYGVIKGSAINQAGRTNGMTAPSVTSQKELI
                     QEVYTKSQINPETIGYIEAHGTGTMLGDLMELKALSVAFKEITDKSQFCVVGSHKPNIG
                     HATLASGMAGLFKILMAMKDQVLPPHRPTGQGQDHFLNSPFVFNTKLRQWKSHPDMPLR
                     AGLNALGSNGTNAHIIIEE"
     aSModule        11285..14458
                     /complete
                     /domains="nrpspksdomains_ctg18_11_PKS_KS.1"
                     /domains="nrpspksdomains_ctg18_11_Trans-AT_docking.1"
                     /domains="nrpspksdomains_ctg18_11_cMT.1"
                     /domains="nrpspksdomains_ctg18_11_PKS_PP.1"
                     /locus_tags="ctg18_11"
                     /monomer_pairings="mal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       11534..11560
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0001"
                     /evalue="1.20E-01"
                     /label="PKSI-KS_m2"
                     /locus_tag="ctg18_11"
                     /protein_end="196"
                     /protein_start="187"
                     /score="5.8"
                     /tool="antismash"
                     /translation="DPQQRLCLE"
     CDS_motif       11753..11800
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0002"
                     /evalue="4.80E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg18_11"
                     /protein_end="276"
                     /protein_start="260"
                     /score="21.6"
                     /tool="antismash"
                     /translation="GPSLTVDTACSSSLVA"
     CDS_motif       11942..11980
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0003"
                     /evalue="6.80E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg18_11"
                     /protein_end="336"
                     /protein_start="323"
                     /score="6.9"
                     /tool="antismash"
                     /translation="FDPQANGMVLGEG"
     CDS_motif       12173..12220
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0004"
                     /evalue="1.40E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg18_11"
                     /protein_end="416"
                     /protein_start="400"
                     /score="11.2"
                     /tool="antismash"
                     /translation="YIEAHGTGTMLGDLME"
     CDS_motif       12281..12325
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0005"
                     /evalue="2.30E-01"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg18_11"
                     /protein_end="451"
                     /protein_start="436"
                     /score="5.2"
                     /tool="antismash"
                     /translation="GSHKPNIGHATLASG"
     aSDomain        12587..13054
                     /aSDomain="Trans-AT_docking"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_Trans-AT_docking.1"
                     /evalue="1.80E-28"
                     /label="ctg18_11_Trans-AT_docking.1"
                     /locus_tag="ctg18_11"
                     /protein_end="694"
                     /protein_start="538"
                     /score="91.7"
                     /tool="antismash"
                     /translation="YLFLFSAKNIEALHQRLIDLADWLEHDGEQYSAEEVAYTLSAARS
                     HFDVRYAFIASGLMDLRHHLRKVIQEGFELGGLWHQRASTFQPASEKLNNGQQLIHTLS
                     NGTVLHQDTYQEYVAKLSDLYIQGYDLDWTGLYHKNRKVPLPSYPFCKTSYW"
     aSDomain        13514..14164
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_cMT.1"
                     /domain_subtypes="cMT"
                     /evalue="4.80E-81"
                     /label="ctg18_11_cMT.1"
                     /locus_tag="ctg18_11"
                     /protein_end="1064"
                     /protein_start="847"
                     /score="264.0"
                     /tool="antismash"
                     /translation="VEGIYQNNAVADYFNHLLAQKVIDYIQERLRQNPDARIRIIEIGA
                     GTGGTSVRVLDHLKSYLGHLEDYCYTDISKAFLVYAEKRFKADYPFVSYRVYNAEAEAA
                     EQGISIDTYDIAIATNVLHATKNIMQTLRRVKAVLKADGLLILNEISDNSLFLHLTFGL
                     LEGWWLFQDDTLRLPGGPAVSAEGWRRVLEQEGFKQVRFPAVEDHTKGQQIIMA"
     CDS_motif       13685..13711
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0006"
                     /evalue="5.70E+01"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg18_11"
                     /protein_end="913"
                     /protein_start="904"
                     /score="-1.3"
                     /tool="antismash"
                     /translation="LKSYLGHLE"
     aSDomain        14225..14458
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_PKS_PP.1"
                     /evalue="4.80E-13"
                     /label="ctg18_11_PKS_PP.1"
                     /locus_tag="ctg18_11"
                     /protein_end="1162"
                     /protein_start="1084"
                     /score="41.2"
                     /tool="antismash"
                     /translation="NHHIAAALKNWMAEHISHALSTEAQAIDFRAAFRDYGVDSISGNN
                     LVQVINQTFFLDLGTTILFDYSSIDQLTNFLLT"
     aSDomain        14603..15856
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_PKS_KS.2"
                     /domain_subtypes="Trans-AT-KS"
                     /domain_subtypes="alphaMe"
                     /evalue="7.60E-165"
                     /label="ctg18_11_PKS_KS.2"
                     /locus_tag="ctg18_11"
                     /protein_end="1628"
                     /protein_start="1210"
                     /score="540.7"
                     /specificity="transATor: alphaMe"
                     /tool="antismash"
                     /translation="IAIVGISGKFANSENVHALWEHLSKGTNLIDHTSRWRRPGDKDET
                     VKSWEKGSFIEDIDQFDPFFFNISGVEASYMDPQQRLFLMASWQALEDAGYAGKSIEGR
                     LCGVYAGCNSGDYHHLMNDYPSREVPQAFWGNLASIIPARIAYYLNLQGPAIAVDTACS
                     SSLVAMHLACQGLWTGEIEMALAGGVSIQCTPELYQAEHQAGMLSPTGQCYTFDDRANG
                     FIPGEGVGVVVLKRLEDALADGDHIYGVVRGSGINQDGTTNGITAPSLRSQVRLERAVY
                     DQFGINPEEIQMIEAHGTGTKLGDPIEYQALTQAFQHYTDEKSYCAIGSIKTNIGHAQL
                     AAGIAGVIKILLALKHRKIPPSLHFEQGNSNIQFKDSPFFVNTELKEWEVKPGAKRCAA
                     VSSFGVSGTNAHMVIEEAP"
     aSModule        14603..16351
                     /domains="nrpspksdomains_ctg18_11_PKS_KS.2"
                     /domains="nrpspksdomains_ctg18_11_Trans-AT_docking.2"
                     /incomplete
                     /locus_tags="ctg18_11"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       14831..14857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0007"
                     /evalue="5.00E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="ctg18_11"
                     /protein_end="1295"
                     /protein_start="1286"
                     /score="6.9"
                     /tool="antismash"
                     /translation="DPQQRLFLM"
     CDS_motif       15059..15106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0008"
                     /evalue="2.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ctg18_11"
                     /protein_end="1378"
                     /protein_start="1362"
                     /score="19.5"
                     /tool="antismash"
                     /translation="GPAIAVDTACSSSLVA"
     CDS_motif       15248..15286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0009"
                     /evalue="5.20E-03"
                     /label="PKSI-KS_m4"
                     /locus_tag="ctg18_11"
                     /protein_end="1438"
                     /protein_start="1425"
                     /score="10.2"
                     /tool="antismash"
                     /translation="FDDRANGFIPGEG"
     CDS_motif       15482..15526
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0010"
                     /evalue="2.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg18_11"
                     /protein_end="1518"
                     /protein_start="1503"
                     /score="13.2"
                     /tool="antismash"
                     /translation="IEAHGTGTKLGDPIE"
     CDS_motif       15587..15631
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg18_11_0011"
                     /evalue="9.50E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ctg18_11"
                     /protein_end="1553"
                     /protein_start="1538"
                     /score="9.0"
                     /tool="antismash"
                     /translation="GSIKTNIGHAQLAAG"
     aSDomain        15890..16351
                     /aSDomain="Trans-AT_docking"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg18_11_Trans-AT_docking.2"
                     /evalue="1.40E-33"
                     /label="ctg18_11_Trans-AT_docking.2"
                     /locus_tag="ctg18_11"
                     /protein_end="1793"
                     /protein_start="1639"
                     /score="108.2"
                     /tool="antismash"
                     /translation="YLLVLSARSEEALRKQAQQLIDYSKENQEGVGDICYTLLVGRQHF
                     KHRLSCVVRDQHDMVAQLEEWIENKAISSVFTHTVHESEHREQPALKKFGNHCIRQSDV
                     NEEEYMDNLSTVADLFVQGYELDYPALFANGQYSRVPLPTYPFAMERYWV"
ORIGIN
        1 gtagagcaac tgacttgtaa tcagtaggtt gggggttcaa gtcctcttgc cggcactgtt
       61 ttttcaaaat ttaatgtgga ggggtagcga agtggctaaa cgcggcggac tgtaaatccg
      121 ctccctcagg gttcggcagt tcgaatctgc ccccctccac catttatagg ggcatagttt
      181 aacggtagaa cagaggtctc caaaacctcc ggtgtgggtt cgattcctac tgcccctgcc
      241 aaatttatga catcttgaga ttatggcggt tgtggcgaag tggttaacgc accagattgt
      301 ggctctggca ctcgtgggtt cgattcccat caatcgcccc atattatcat tgggctatag
      361 ccaagcggta aggcaacgga ctttgactcc gtcatgcgtt ggttcgaatc cagctagccc
      421 agtctcattt tttatatcaa cgatgtatta agtccattaa aaatgcggaa gtagttcagt
      481 ggtagaacac caccttgcca aggtgggggt cgcgggttcg aatcccgtct tccgctccaa
      541 ttacggcggc atagccaagt ggtaaggcag aggtctgcaa aacctttatc cccggttcga
      601 atccgggtgt cgccttctta ttgccggggt ggtggaattg gcagacacac aggacttaaa
      661 atcctgcggt aggtgactac cgtgccggtt caagtccggc cctcggcacc aattttactt
      721 acatgataag ttgaattggt gtttgtgttt tatcattata actaatcata ttaatgatct
      781 acataagtag atcatttttt taatgctttg atttatcata acaagttaag tttcgaggcc
      841 tattataaag cggctgtata gctcgtcttt caacactttt attttatatt tccaaaaaaa
      901 cttttttgaa atacgttgac actttatgag atccatgata tatttatatt cgtcggttag
      961 atacgacgta aaacttgccg gtgtggcgga attggcagac gcgcacgact caaaatcgtg
     1021 ttccttctgg agtgtcggtt cgaccccgac caccggtata tacttggtat taacaagata
     1081 tatcagttat tgtaacgtgc aaaaaagata ggtaattacc tatctttttt tgcatgttat
     1141 aatattagta aggtcgttgt tactgtggct cacttacaaa ggcttctttt atattgttat
     1201 cttgcagatt ttcagttaca tatcgaactg acttgttagg acgtagataa tatagttaca
     1261 ttgcccttgt gcctgtttct aactttgaaa gataaaaaga agtaccgcct gttcagactc
     1321 taaaaaacat gaaacaaaca caaccacata tcaaagcaaa taaaagtaat attaccaatt
     1381 aaagaaacat aggcttcaac cttgtatcct ggtattatgc cctctatgta tagataatgt
     1441 aaagccctta tcaaaagtga ctattactct atacttagag gcttttttta aaaaaactaa
     1501 gataattggt cttcatacat gtttatgtaa aagaaaccaa aggttaattt gacaacctaa
     1561 tactactgtt tactctatca cgagaagcat tctttataac atataatcac ttgcgcttct
     1621 ctatatgaaa ctttatacca gatttatttt ttacattact aacaattttc tctttatccg
     1681 tttacccgtg tgtggcatta taattcctat gttgtcacaa agtatccgta tttttgaatt
     1741 ttttgatatt tcatatttac atttagaaga attattagta aactttaact gtaaatggaa
     1801 ttacaaatag gataggacga atgttgtact actaattaaa agtttacttt aagctaacta
     1861 aaaatttttg tatacgttgt gtaatacttc aactgttttt tttcggggac ctatactttt
     1921 tctatataac ataaaaagaa ccacagaaag ttaatcgttg tttcggcacg ttaatggact
     1981 aaggggataa tagagagtag tgttagcgta gtgctggtta ctcctggacg atagggcgaa
     2041 gctatgcctt ttattcaaat gttgaaaggg atgggtattt gaatgtcttg gtatgtcctt
     2101 tatgtcgaaa caggtcaaga agaaattgtg aaatgtttaa tcaataagta ttttgctgat
     2161 ttaacgattg aggtaattgt tccgaaaaga aagatacgag aaaagcgaca aggtaaatta
     2221 tacgaggtaa gtagactttt attcccaggg tatgtatttc ttaacacgta tatgaatata
     2281 gacatatact atggactcaa aaaaatacca agatgtttcc gtcttctcaa ttcatataaa
     2341 tataaaactg attatctggt agacgatgtg agtcataata taactagtgt cttctgcacg
     2401 attgaacaag gagaaatcgc gccaattctt cagttattgc aacaaaatga aacgattggt
     2461 ttttcgcaaa tttacaaaga agattcagaa ataactgtca tttctggtcc tttaaagggg
     2521 cttgaaggca ttataaaaaa aatcgataag cgtaaaaaca gagccaaaat tgagttgaat
     2581 tttatgggag taataaaatt ggttgatgtg ggagttgaag tgttaaccag agacagttaa
     2641 ttaaaatctt aatattaaaa ttcaaacttg taaacgagcc cctttccaag ggaaaattca
     2701 tattttccct tggaaagggg actttttgta tgtcaggttt tagctaataa tattaggaga
     2761 gtggtgtcta ttgttaggtg tgatgaggtt atgaaggaaa aaatcatttt tatgttttca
     2821 ggacaaggtt ctcaatactt taaaatggga aaggagttgt atgaatatga atcgattttc
     2881 agtaaagaca tgggtcagct ggatgctgta tttcaaaaag ccactggaaa atcgataatt
     2941 aattatatct acaatgaaca tcgtttaaaa agcgatattt ttagtgactt gttctatacg
     3001 caccctgcaa tttttataac agaagttgct ttggcccgtt tgctggtttc aaaaggaata
     3061 cgtcctcatg cggtaatagg gtctagtatg ggtgaatatg ctgctgctgt agtggctgat
     3121 gttttccaac cagaagagtt tctaaatatt ttgattgagc aagttaaact attgaatgag
     3181 tttagttcac cgggaggaat gatggcgatc ctagatacac ataaaattta tgatgaggtt
     3241 ccaattcttc atcatcatgc caatctcgct gcaattaaca atgaatcgca ttttgtaata
     3301 agtgctaatc aggaaggaat aaaaacggtg gagcgatatc ttcgcttaaa agaaattact
     3361 tatcataagc tacctgtaac aattcctttc cattcagagc atattgaatt ggcgagcgaa
     3421 gcagttcaag agagtttgtc tcaaatatca tttaaatcac cgtgtcttcc gttttattcc
     3481 tctgtgtctg ggaaaaagct agaacatttg actgctgagt atttttggaa tgtgctaaaa
     3541 aagccaatcc attttattag agctttaaca gaagcggtgg atcatggagg gacaattttg
     3601 atagatttag ggccctcagg cacattagcc aacctagcca aagctcattt taggaatcgt
     3661 acagatatat ctatttttag tattctttca ccatatactg ataacgtcag ggcattagaa
     3721 agtgtgtata ccaagagtgt ccaataatgt gaaaatgaat caaaaaaaac taaggaggaa
     3781 gataatagag tgaataaaag aattattcag ttggcctttc caatttttat tgaaagcgct
     3841 ctggttatgg ttgatggtct tattcatata atttgggttg ggcaattagt tggcggtaag
     3901 gcagtagctg cggttggtgc ttgctttcct atcattttgg caatgtcagc aatcgctaac
     3961 ggagcggcaa aattaacttc aacacccatg ttacagcgtt ttctttctaa gaaaaatcga
     4021 gatgatgtgg tgcaaaaaca aattaatgtc tcatggtctt ttgccatctt tatagtactg
     4081 cttgtgacag tgggaattta tcttgctgct caatggattc taaaaatgct gggaacacct
     4141 gagggtatta ttgaactggc aataggatat cttcaaatta tggccattgg tttcactatt
     4201 atgtatttct catttttaat tacatccctg ctgagggatg ttgggtataa gtttgcacgg
     4261 atgcttttta ttgtgattgc cacagctgga aatttagtgc tggtccccat gtggattata
     4321 gggatcgggc cctttcctaa gttgggatta tatggggcag tatttgcttc ttttattgtt
     4381 tcgattattg ctatcatcgt ttctgtgggc tatctcttac gacattataa aggcttactc
     4441 attaaaccga caaaattaag atgggatcgc gacattctag tctcattatt accggtaagc
     4501 atccctgttt ttttacaaca gtttctattg gctttggggt acacatgcat tattattttt
     4561 gtcaatcctt ttgggatcga tgcgacagcg gcattctata tcattagccg aattgattcc
     4621 cttgtggcac taccggcaat tgcggttatg attgctatgt cgatcctaac aaaacaattg
     4681 gtgcaggggg agaaactgga gagaatcaag agtctttttc attcggggct actcattaat
     4741 tttccattga catttttaat agcattgtcc tgttttctct tccctgaatg gattataagg
     4801 atctttataa ctgccccatc tattgtcacg attggtgcag attatttgaa aatcatcagc
     4861 tttggctatc tcctttttac acttttatat gcttgtaatg gcatcattaa cggggctgga
     4921 aaaggaggga tcaccttagt tttttcctta gcttccctcc ttgtaatcag ggtgcctgct
     4981 gcagcgatac ttacacaagc gggctttaaa gtaacgggcg tatggttcgc agttctaact
     5041 agctttatcg cgttggcaat atgcagttgg ttatattatc tatctggttt atggaggaaa
     5101 aaattggatg ttaaagaaat gaaaacacag agagttatgc catcttaaat aagttagacc
     5161 gctaagcggc taacttttga agctcaagtc acgggggaag ggaaaatatt atctttgaag
     5221 gagtgatgag atatgtctga aaatccaacc aagagttaca agggaccggg aatgaacggt
     5281 gttattggta cttggtatgc gaagaacacg cagaaaaaaa tcgaaaaata tacacgggat
     5341 gcgaagaagg ttttaaaggc cttatctgat ggggattctg tgctggagct agctcctggt
     5401 cctggctatt tatcgattga actggctaag ttagggaatt ttcagatttt cggggtggat
     5461 attagcgata agtttgtgca catggcacag aacaatgccg gcaaagcagg ggtggacgtt
     5521 gatttccgtc atggtgatgc ggcacagatc ccgtttgatg atgaatcctt taatctggtc
     5581 gtttgccggg cggcttttaa gaattttgct caaccggtca tagcactaaa tgagatgaaa
     5641 agagtattaa aaccgggagg taaggcagtc atcatcgatt ttaaagggga tgtgcccaaa
     5701 gcagatatca ataaatttgt aacggatgat atgggattca aaggcctgaa tgccatgata
     5761 attaagtgga tgtttcgaaa tgtagtgatt aagcaagcct atacgaaaga gaagtttatg
     5821 gcattcgtca aagagagtaa ctttgagaca tgtgacttaa aagaaggtct cattggaata
     5881 gaggcttggt tagagagata gttgacagcg tttgtaaatg aaaatagata ttgatatttt
     5941 gatggagtca aaggaactta ttcttcgaga ctctcttttt tatttcaaaa tcgggttttg
     6001 attatcatgc attgaaatga ttttgatagc taagtttaga taaagcatat ttcactggtg
     6061 agaaaggatg aataggatgt acaatgaaaa cttgccgatg ctgtggacaa cccgcctggc
     6121 ttttaaaagg gaggaagaac aggactttcc atcgacttgt tgcctatgct attcagactc
     6181 atttcacgat tatctacaaa caaaatcatt tcttcatcca aaggaaaggg tctattttag
     6241 ccaattgcag tttaatagga gaataaaaag ctacttggcg ggcagatatg caggaaaaaa
     6301 tgctgtatca ctgctaagtg gggaagagaa attaagtgca attgcaattg aaccggggat
     6361 tttccatcaa ccggttgttc actttccagg caggtcagca attcaagtca ccatctctca
     6421 ttgtgatgat ttaggcatgg cactcgcata cccggatacc tgcccactag gtgttgatat
     6481 tgagcggctt caagcggata aacaagcggt attggctggt cagatgacgg ctgaagagca
     6541 tggtttgata caatcactgc ctttttcttc agttcaatcg ctcacccttt tctggacagt
     6601 caaagaaagc ttgtctaaag tgttgaaaac ggggtttata tccccgattg acatctttgc
     6661 cattcgtaca gtggaggtag cccatcctgt ggtaacaagc tactttgaaa actttccaca
     6721 gtattgtgcc acctcgtttt tttttacatc ttatgtttgt tccattaccc atccaaaagg
     6781 agttgattgg ccaaaagatt ctatttaccg cttattatct caggtaactc cagtattaga
     6841 gaggataaat acatagattg atggtatgcc aataacccga tgttatatga ttttgaaaac
     6901 taaaaaagaa ggggataaga gaatgaccgt ttatgttttt ccaggacaag ggtctcagaa
     6961 aaagggaatg ggcgaggggt tatttacaga attccctcat ttaactaagc aggccgatga
     7021 tatactgggg tattccattc agacattatg tttggaaaac ccagaggaga gtctaggaaa
     7081 aacccaatat acgcagcctg cattgtttgt cgttaatgca tttcattatt taaaaaggaa
     7141 aaaggaagcg aatgaaaagc cgaattattt ggcaggacac agtctgggag agtataatgc
     7201 tctttttgcc gcaggggtat ttgattttga aacaggtctt aagttggtta aaaaaagagg
     7261 cgagttgatg agtcagtgct atggtggcgg gatggcggca gttgttggct tgaatgaaca
     7321 ggagattgcg gaagttttgg cctttaacgg gttggctcaa ctggatattg ccaactacaa
     7381 ctcaccgaca cagatggttt tatccggttc acaagaagat attacgcgag caaaggggat
     7441 ctttgagcag acaccaaatg tccagttgtt tgtcccgcta aacacaagtg gtgcttttca
     7501 ttctcgttat atgcaaaaag ttaaatctga attttctgac tacttgggtg aattttcttt
     7561 ctttgcccca gccattccta tcatatctaa tgttgaggca agaccgtatg gggaaaatat
     7621 taaggataat ctcattgcac aaattgatca tcctgtgaaa tggacggaaa gtatccgata
     7681 tttaatgggc aaaggggaaa cggactatct agaacttggg ccgggtcatg tcttaaccaa
     7741 tttagttaac caaattaaaa ggaaagcaag tcctttgatc gtagaggaca agccaacact
     7801 agttatagaa gagattgaaa agacggctga aaaagcgccg tcgcctgata taccctcccg
     7861 cttaacagct tcttccctgg ggagtgacag ttttaagaag gattataacc tcaaatatgc
     7921 gtacttaact ggcgggatgt atcggggcat ttcctcaact agtttagtag tgcgtgtcgg
     7981 caaagaaggt atgatgggtt tttttggaag tggcgggttg aaactaacgg aaatagaaca
     8041 ggctattgtc acgattcaaa aggagttatg ccagggggaa ccctatggtt ttaatctagt
     8101 tcaccagttt aatcatccgc aaagggaaga agaaatcgtt aatctatttt taaaaaatgg
     8161 cgtgactgtc attgaggcct ccgcttttct aggtgtgacg cctgccttaa tcatctatcg
     8221 ggcgaaaggc ttaaagccct ctgctgatgg ctcaattgga tgccacaatc gcatcattgc
     8281 caaaatctcc cgtccggaag tcgctgaggc tttcttaagc cctgcccctg aacgcctgct
     8341 gaataagctg gaaatggaag ggggaatcac ttcccaggaa gcgaaatggc ttcggcaggt
     8401 tcccatggca gatgatatta ctgtagaagc tgattcaggc ggacatacag acagtggcgt
     8461 ttcctatgcg ttgttgccga ccattattcg gttacgggat cgtcttgtag caaaatacgc
     8521 ctataaaaaa gagattcgta tcggtgcggc aggtggcatt ggtacccctg aggctgctgc
     8581 tgcggctttt acccttggag cagcatatat actcacaggt tccgttaatc aatgtaccgt
     8641 ggaagcgaac accagcgatg ctgtaaaaga tttgttgcaa caaatgaatg tacaggatac
     8701 tgattatgcg ccggctgggg atctgtttga acttggctcc aaaattcaag tgttgaaaaa
     8761 aggagtgttc ttccctgccc gtgccaataa actttgggaa ttataccgcc actatgaatc
     8821 ttgggaagcg attgatgaaa aaacacggca ccatatcgaa gaattatatt ttaaatgccc
     8881 ttatgaagag gtatatgcaa aagtaaaact tcactactcg ccggaagaat tacagaagat
     8941 cgaaaacaac ccaaaacata aaatggcggc gatctttaaa tggtacttcc actatagtaa
     9001 tcaactggct ctaagcggta atccggaatt caaagtagat tatcaaattc attgcggacc
     9061 cgccttaggt tcctttaacg agtgggtcaa agggacgggg ttagaaaact ggcggaaccg
     9121 tcacgcggat tacatcggaa aatatttaat ggatgaaacg gcacagctat tgactgaacg
     9181 ttttcagcag cttctgcctg taaaagaatc cctagcattt caaactatta catgataagg
     9241 agaaaaaacg aatgaaaaaa gaagacatct tttctatatt agtacagcat acacgtgaga
     9301 ttgtaccgga acttgaacag catcactttc aatgggatga ccgattggcg gatttaggtg
     9361 ccaattccgt agatcgtgcc gagattatta tggagacatt agaagctctt tctttgcaaa
     9421 ttcctagaat tgaattgtcg gaagcccgga acctcggagg tttggcggaa atcctttatg
     9481 aaaaatgcag catgcatgat ttataatcta tattccctaa aaatgagcta tcactttttt
     9541 atcaactata cctatctgat tgtggagcca aacaccagaa atgctattgt agttgatcca
     9601 gcatgggaat tagatagaat cacccagcaa cttgaaaaaa aacatgctaa tctccgagct
     9661 attcttttga ctcattctca ttatgatcat gtcaatttgg taccagcact aagcgatctt
     9721 atgcaaccgg atgtattttt gtcccaaaag gaaattgatg catcaggttt tcgatgtaaa
     9781 cgattgaatg ctatcaatga taatgactgt cttttattgg gagaattgcc gtttcattgc
     9841 ttgctgaccc ctggtcatac tatgggtagc atgtgtttcc aactggataa aagccttttt
     9901 acaggtgata ccctgtttac agaaggatgc ggtgtctgtc ccaggcctgg cggttctcca
     9961 gaagcgatgt atcttagcat acaacgaata aaagcggaaa tagaagatga tgtccgtatc
    10021 tttccggggc actcgtttgg tatgtcaccg ggaaagacga tggggcatct ccgtaagaat
    10081 aacatttatc ttcaactaaa ccgcgaacat tttattaaat ttcgcatgcg aaaaaatcaa
    10141 cgtggcatct ttgattttca atagaaagga aggggcaata tgggagaact tgaagtcata
    10201 catgcaaacc ctactgggat gcctaaaaca ccaccacttc tctttgttca tggggcaaat
    10261 catgcggcct ggtgctggaa ggaaaatttc cttccttttt ttcaatctca tggtttccag
    10321 tcctatgccc taagctttcg tgggcacggc catagtgagg ggcgtggaaa tctacatacc
    10381 tttacgatgg aagactacgt agaagatgta tacaacgtgc tagaaaccct agagcaaaaa
    10441 cccattatta ttggtcattc catgggagga gcagttgtac aaaaagtgat gcatcagcat
    10501 ccggacagga ttgaggcagc tgtacttatt gcttcaatcc cacctggggg aatgttaaag
    10561 gatttttttc ggctactgtt aatgcatcct aagaaatttc gccaactctc tttatataat
    10621 cagggaaaaa ccactgtctt cccagtggat ttatttttgt ctggcgagac accagaagaa
    10681 ctgcaggctt ctttagtcgg gaagctgcaa ccagaatcaa caaaagctag ccgtgattgc
    10741 ctaaaacgcg tggtccccaa aaatacagta gcccaggttc ctcttttggt attgggcact
    10801 gatggggata ccatgatctc aaaaaaaact acgcagtcca ttgggcgttt ttatcaaaca
    10861 gagccggtta tttttccgaa aatgtgccat gatatgatgc tggaccccga ttggcggaag
    10921 gtggctgaac agatccttgc tttttcactt agagaggagg agcgaatggt agatgaagca
    10981 tgatcgaagg gtacgaaacc cggttaaaga gaaattagtt gaagagttta ttcaggtggt
    11041 tggtgagcag gatcagccca ttgatctcaa taaaagcttt ctggaactgg gtatgaattc
    11101 cataaaagca gttgactttg ttgaagctgt taataacagt ctgggattag agttgggtgt
    11161 tgaagtaatc tttgattttc gtggcattcc cgaattggct gaacatatag cggaactata
    11221 ctcggcagag gaagaaaaaa acccttctcc tgagtctgct ttaaacagcg attcatctat
    11281 ggatattgcg attattggaa tatcagggaa gtttgctgac tcagaaaata ttgaagatct
    11341 gtggtctcat ctcaaagcgg gggaatgttg cattaaagaa gttcgacgca gggggtggga
    11401 tgaaaagacg tactatacac cagaagcagt ccagaaaaat cggtcagtca gtaaatgggg
    11461 cggcatgttg tcgcatattg atcaatttga tgccggcttt tttgatattt cttcagagga
    11521 agcagaaagg atggacccgc aacaacgcct ctgtttagag gaatcctata aagcctttga
    11581 ggatgccgat taccctgctg aaaaattggc ggggaaaaag gtgggcgtgt ttataggtgg
    11641 acgcacatcc gactatcgga agcgattatg gaagaaaatg gataccttta acttttgggg
    11701 caatgaaatg tcgatgctgg catcacggct ttattacttt tttaatttca aaggtcctag
    11761 cctgacagtt gatactgctt gttcatcctc cttggttgcc attcatttgg cttgtgacag
    11821 tatccgcaag ggtgagtcgg aaatggctct agctggtggg gtttttattg caagcacgcc
    11881 tgaatttttt aagatgtctt cccaagctgg tttattatcg ccagatggtc aatgcaaagc
    11941 ttttgatccc caggctaatg gcatggtttt aggtgaaggc gtgggggtgg ccgttttaaa
    12001 aaggcttgat gacgcggtac gggaccagga ccatatctat ggggttatta aaggatctgc
    12061 tattaaccaa gctggcagaa cgaatggtat gacagcacca agtgtcactt ctcaaaaaga
    12121 attaatccaa gaagtgtaca ccaaatcaca gattaatccc gaaacgatag gctatataga
    12181 ggctcatggt acaggtacca tgcttggtga tttaatggag ctaaaggcct tgtcagtagc
    12241 atttaaagaa attacagata aatcccaatt ttgtgttgtt ggttcccata agcccaacat
    12301 tggacatgcc acgctggcat ccggaatggc cggtttattt aagattctaa tggcgatgaa
    12361 agatcaagtg ttaccgccac accgtccaac tggacagggg caagatcatt ttttaaacag
    12421 tccttttgta tttaatacca agttgcgtca gtggaaatca catcctgata tgccattgag
    12481 ggctggttta aatgcgctag gctccaatgg gacgaatgcc catatcatta ttgaggaatg
    12541 ggtagaacaa tcagtacaat ctatatctcc aattcaaaag ccctattatt tatttttgtt
    12601 ttctgctaaa aacatagaag ccttacatca aaggctaatc gatctagctg attggctaga
    12661 gcacgatggc gagcagtact ccgcagaaga agtggcgtat accttatcgg cggcacgtag
    12721 tcactttgat gttcgttatg ccttcattgc cagtggctta atggatctaa ggcatcacct
    12781 gcgcaaagtg atacaagagg gattcgagct aggaggattg tggcaccagc gggcctccac
    12841 ttttcaacct gcttccgaaa agctgaataa cgggcaacag ttgattcata ctttatcgaa
    12901 tggtacggtt ttgcatcagg atacatatca ggaatatgta gcaaaactat ccgatctgta
    12961 tatacagggt tatgacctgg attggaccgg tctatatcat aaaaatagga aggtgcctct
    13021 cccatcatat cctttttgca aaacaagtta ttggacaaca gagcaggagg ataccgctgt
    13081 acaagaacct gctgttttct catcatatgg tctgcaaatg cgtgatatgg aggaactgct
    13141 tgttaagtta ctgttaaagc aattgcagtc tctgggtatt ttagctgacc agcggatgac
    13201 attggcggat atgcaaaaga aactggggat gtcttatatc tatcgtaaat ggttggcacg
    13261 cagtcttcag tttttagttg ataagcaatg ggtggtttgt gatgaaaccg atcaatatag
    13321 cttgaatcct tctattgaga aagagcaaga tgcatgggaa gtctgggaac gacaaaaaca
    13381 acattggttg gcaactcctg atgccaggat gcagacgatt ttggtagaac atacccttcg
    13441 ttctttgccg cggatattga ctggtgaggt actggcaacg gatattatat tccccaattc
    13501 ttcgatggaa ctggtggaag gaatctatca aaataatgca gttgctgatt attttaatca
    13561 tcttcttgcc cagaaagtaa ttgattacat tcaagaacgc ttacgtcaaa acccagatgc
    13621 acgtatacgt atcattgaaa taggtgcagg cacaggggga accagtgtcc gtgtattgga
    13681 tcatctaaaa tcctatctcg gccatctaga agactattgc tataccgaca tctcaaaagc
    13741 ctttctggtc tatgcagaaa aaaggtttaa agcagactat ccctttgtct cctatagggt
    13801 ttataatgct gaggctgaag ccgcggaaca aggcatctca atcgatacgt atgatattgc
    13861 cattgcgacc aatgtgcttc atgccacaaa aaatattatg cagacattgc gtcgggttaa
    13921 agcagtgtta aaggcagatg gtttgctgat tttaaatgag attagtgata attccctatt
    13981 ccttcacctt acgttcggcc ttttggaagg ttggtggtta ttccaagatg atacactgcg
    14041 tctacccggc ggcccagctg tatctgcgga gggatggaga cgggtattgg agcaggaagg
    14101 ttttaaacag gttcgttttc ctgcagtaga ggatcataca aagggtcagc agattattat
    14161 ggctttcagt aatggacacg tgcgccaaga ggcggcacaa aaacaacccg ctgtcaccac
    14221 aaagaatcat cacatagcgg cagccttgaa aaactggatg gccgaacaca tatctcacgc
    14281 tttatcgacc gaagctcaag caattgattt tcgggctgcc tttcgcgatt acggcgttga
    14341 ttctataagt ggcaacaatt tggtgcaggt gattaatcag acctttttcc ttgatttggg
    14401 aactaccatc ctctttgact atagctctat tgatcaacta acaaattttc ttttgaccca
    14461 ttacaaggat gctattgccg ctttttttgg gaaggagaaa ccacctgcgg aagaaaccac
    14521 tattggtcat ttggaagagc gcaaagaagt attgagtacc catgagacga aacaggtgtc
    14581 aaaaggcaga cagaaaggac ccattgctat tgtaggtatc agcggcaagt ttgccaattc
    14641 tgaaaatgtg catgcattat gggagcatct gtctaaagga accaatttga ttgatcacac
    14701 atctcgctgg cgacgtccag gtgataaaga tgaaacagtg aaaagttggg agaaaggcag
    14761 ttttattgag gatattgatc agtttgaccc tttcttcttt aatatttcag gggtagaagc
    14821 aagttatatg gatcctcagc aacgactctt tttaatggca tcatggcaag ccttagagga
    14881 tgctggttat gctggaaaaa gcattgaagg tcggttgtgt ggcgtttatg ctggatgcaa
    14941 cagtggtgat tatcatcacc ttatgaatga ttatccttct cgtgaggtgc cccaagcttt
    15001 ttgggggaat ttagcttcta tcattcctgc tcggattgcc tattatctca atctacaggg
    15061 tccggccatt gccgtagata ccgcctgttc cagttcactg gtggctatgc atttggcttg
    15121 tcagggttta tggacgggcg aaatagagat ggcattagct ggcggtgtat ccatacaatg
    15181 tacaccggag ttatatcaag cagagcatca ggcggggatg ttatctccaa cggggcaatg
    15241 ctacaccttt gatgatcggg ccaacggatt tattccaggt gaaggggttg gtgtagtcgt
    15301 acttaaacgg ctagaagacg cccttgctga tggtgaccac atttatggag tggttcgggg
    15361 ttccggtata aatcaagatg gtactaccaa tggaattaca gcgcccagcc ttcgttccca
    15421 ggtgcggtta gaacgggctg tctatgacca atttggtatc aatccggaag agattcagat
    15481 gatagaagcg catggcacgg gaacgaaatt gggagacccg attgaatatc aggcactgac
    15541 acaggcattt caacattaca cagatgagaa gtcatattgc gctataggct cgattaaaac
    15601 caatattggt catgcgcaat tggccgctgg aattgctggt gtgattaaga ttctgttggc
    15661 attaaaacac cgtaaaatcc ctccttcgct gcactttgaa caggggaata gcaatattca
    15721 atttaaggat agtccctttt ttgtgaatac cgagctaaaa gagtgggagg tcaaaccggg
    15781 tgctaaacgc tgtgccgctg ttagctcttt tggtgtgagc ggcaccaatg cgcatatggt
    15841 gattgaagag gcacccgatg tgattcgcaa gcacccggtt cagcctggct atttattggt
    15901 cttgtctgcc cgctctgagg aggctttgcg aaaacaagcc cagcaactga ttgattatag
    15961 taaagaaaat caggagggtg taggggatat atgctatacc ttattggtgg gccgacagca
    16021 ttttaaacac cgtttatcct gtgtagtacg tgatcagcat gatatggttg cacaattaga
    16081 ggaatggatt gagaataaag cgatttcctc tgtatttact catactgtac atgagagcga
    16141 acatagagaa cagccggctt taaaaaagtt tggaaatcat tgtattcgcc agagcgatgt
    16201 taacgaggaa gagtatatgg acaacctttc aacggtggcg gatttgtttg ttcaagggta
    16261 tgaactcgat tatccggccc tgtttgcgaa cggacaatat agccgggtgc cgctgcccac
    16321 ctatcctttt gccatggagc gttattgggt accgcaacca gatgcggatg tggctcctgc
    16381 gagggaggct acagttaaag ccgcccctac gcagcctcaa gctgccgaag aggtggcggc
    16441 ctctactgag gaaggccagt tgatgacgtt cgctgagagc tggcagcgac aagacttgac
    16501 cgatgagcgg atgcccctgc cttcggtatg ggtctgtttt ctatccaatc ccgcgcacca
    16561 acaggcgttg cgcaccgtcc ttcaaacccg ctatccggag acggaggtca tttttgttgc
    16621 gcagggtacg gcggagcgtc gggaaagccc gcatcactac cagttgaacc gagaggatgg
    16681 cgtggcctat cggcaaaccc tccaacgcat agcggctgac tggggtccgg gttttgccct
    16741 gctctatctg tggcctttgg aggatccggc tgtcattagc gatta
//
