LOCUS       gnlProkkaGNCMBPMD_1    23227 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GNCMBPMD_1.
ACCESSION   gnlProkkaGNCMBPMD_1
VERSION     gnlProkkaGNCMBPMD_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 21:50:11
            Original ID  :: gnl|Prokka|GNCMBPMD_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 912165
            Orig. end    :: 935392
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23227
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13227]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13227
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..23227
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23227
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RaS-RiPP"
                     /region_number="4"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             795..1454
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 180.3; E-value: 6.9e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_941"
                     /transl_table=11
                     /translation="MARILVIDDQKDIVQLVVKALELQNHNVTGLTSVLDLDKNSLPRF
                     DLILLDIMMPDVDGLQFCHEIRNQVDCPILFITAKTQEADIVQGLSYGADDYICKPFGV
                     KELQARVAAHLRREHRERHHKLSLGEFQFDLSAQELYIENQLLDLTKSEYGICQFLAEN
                     KGQVFSKEQIYTHLYGYEDKGSPAAVAEHIKNIRAKLKEVGQNPIETVWGIGYKWH"
     CDS             1445..2839
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 125.7; E-value: 4.8e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_942"
                     /transl_table=11
                     /translation="MALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     LIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGEKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDTYVKELSEINKMSLKKTLTLEEVPAKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRHSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
     CDS             2940..4283
                     /locus_tag="ctg1_943"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERSLKDLQTFIDA"
     CDS             complement(4548..5345)
                     /locus_tag="ctg1_944"
                     /transl_table=11
                     /translation="MNVADQKANGIDILTDGEFGRSMWHLDFVWGLKGIERYIAEHGYT
                     FKDHDGGQYETRKDIGIRVTEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHTYTE
                     LAIFDQLAVPGQVYETNEELKKGLINVYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPA
                     SFYSDGNGDLAESADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSAAEGTYEDIAK
                     KFLAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(5342..5497)
                     /locus_tag="ctg1_945"
                     /transl_table=11
                     /translation="MTKSKFQLVGSLLRPADLRKYKDEIEHRDDIQYPFYDALPGYQET
                     ETASIK"
     CDS             5650..6078
                     /locus_tag="ctg1_946"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             6080..6373
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 59.2;
                     E-value: 5.6e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_947"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDDSIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             6584..6925
                     /NRPS_PKS="Domain: PKS_KR (3-112). E-value: 4e-11. Score:
                     35.0. Matches aSDomain: nrpspksdomains_ctg1_948_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     111.9; E-value: 5.8e-34)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_948"
                     /transl_table=11
                     /translation="MSKVAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVE
                     LSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLETITEEQFQRT
                     FNINVGGVI"
     aSDomain        6593..6919
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_948_PKS_KR.1"
                     /evalue="4.00E-11"
                     /label="ctg1_948_PKS_KR.1"
                     /locus_tag="ctg1_948"
                     /protein_end="112"
                     /protein_start="3"
                     /score="35.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGFKVGVLDYDAETAEKAVVELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVHQQNPLETITEEQFQRTFNI
                     NVGGV"
     CDS             7201..7347
                     /locus_tag="ctg1_949"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             7735..9567
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 549.8; E-value:
                     1.4e-166)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_950"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDTIEEPYIKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             10001..10858
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_951"
                     /sec_met_domain="TIGR01716 (E-value: 4.3e-45, bitscore:
                     150.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIS
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSDYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCIAAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             10918..11718
                     /locus_tag="ctg1_952"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEGQRYKDIEDVVLRYIKTGVPVFSPSLHVSEERLKYE
                     IEYQNNFKNTLSEYYRTKTADGTTEFKEYEKWYIYYLDFRWGSIPLSYTSSQANQFWNL
                     YKRVCEDVYKKISYIRTDNIYFIIANQFNKTISKHFQLNFIDKE"
     CDS             11778..11927
                     /locus_tag="ctg1_953"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEVVSSGLSIDIMEIKPSVATELIDGLKGRC
                     PPSV"
     CDS             12010..13227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_954"
                     /sec_met_domain="Streptide_RRE (E-value: 6.3e-15, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.5e-19, bitscore: 67.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.1e-08, bitscore: 30.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.9e-10, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7.8e-08, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSGIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             13224..13967
                     /locus_tag="ctg1_955"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             13974..15146
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 61.4; E-value: 1.2e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_956"
                     /transl_table=11
                     /translation="MKTKKYAALSIYFNRFSSLISEYGYTILINILLSRISVQLVMYFW
                     VVKCLAAIVTNRINISNSKLSRKYLLILLEITKAILLFLLGFGLNHIIVLLVVFIIEVV
                     NVLFSSLLYSCVPIIIDKDSLIKFNARYTSIGSVSYFLAPLFVGLFINKSHFLLFAVYA
                     LLLIVGATSLLFLPNISTLNLKEERKKQNLNITLFNILRSKKIALVLLSGVIVGSIGVV
                     YDTYEVVYLTKYLGISDSMYSFSLSFLAVSFLVMSFLLSFVKQISSHMKAFALGLSFYV
                     LYLLLFSTSSNIYTVLMSYVFLAIGQTMMGIIETNYFQLSLNMKELQKLYIYSETLHSV
                     FSGIAVLVIGSFAFLSSHLVLVFRSLAVFALFILLCYCVFVNLKKLSIDK"
     CDS             15400..17076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 502.8;
                     E-value: 2.1e-152)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_957"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-50, bitscore:
                     168.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.9e-45, bitscore:
                     149.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKQLYGADLVVDSLINHDVEYVFGIPGAKIDRVFDTLEDKGP
                     ELIVARHEQNAAFMAQGVGRITGKPGVVLVTSGPGVSNLATGLVTATDEGDPVLAIGGQ
                     VKRADLLKRAHQSMNNVAMLEPITKYAAEVHDANTLSETVANAYRHAKSGKPGASFISI
                     PQDVTDAPVSVKAIKPMTDPKLGSASVSDINYLAQAIKNAVLPVFLLGNGASSEAVTYS
                     IRQILKHVKLPVVETFQGAGIVSRDLEEDTFFGRVGLFRNQPGDMLLKKSDLVIAIGYD
                     PIEYEARNWNAEISARIIVIDVEPAEVDTYFQPERELIGNVEASLNLLLPAIQGYKLPE
                     GSVEYLKGLKNNVVEDVKFDRQPDEGTVHPLDLIEVLQEQTDDDMTVTVDVGSHYIWMA
                     RYFKSYEPRHLLFSNGMQTLGVALPWAISAALVRPKTKVISVSGDGGFLFSAQELETAV
                     RLKLPIVHIIWNDGHYNMVEFQEEMKYGRSSGVDFGPVDFVKYAESFGAKGYRATSKAA
                     FASLLQEALTQAVDGPVLIDVPIDYRDNIKLGETILPDEFY"
     CDS             17092..17811
                     /locus_tag="ctg1_958"
                     /transl_table=11
                     /translation="MSEAIKLFQYNTLGALMAGLYGGTLTVGELLEHGDLGLGTLDSID
                     GELIVLDGKAYQAKGSEGKVEVVEVSPDEKVPYAAVVPHQAEVIFRQRYEMTDKELEDR
                     IESYYDGVNLFRSIKIKGHFKHMHVRMIPKSNADIKFADVATRQPEYEVDDISGTIVGI
                     WTPEMFHGVSVAGYHLHFISDDLTFGGHVMDFVIENGIIEVGPVDQLDQRFPVQDRQYL
                     FAKFNVDEMRKDITKAE"
     CDS             complement(17863..19119)
                     /gene_functions="other (smcogs) SMCOG1206:transposase
                     (Score: 413.2; E-value: 1.8e-125)"
                     /gene_kind="other"
                     /locus_tag="ctg1_959"
                     /transl_table=11
                     /translation="MRLIKNNTELIGIKDQNIKISLVFETDTHIEIQAKLDYPAPSCPH
                     CHGKMIKYDFQKNSKISLLEQAGTPTLLRLKKRRFQCKSCRRVTVAETSIVEKNCQISN
                     LVRQKVTQLLTEKVSLTDIARRLRVSTSTVYRKLDQFTFKKHYDKLPAVMSWDEFGFKK
                     GELAFVAQNYETNELITILDNRRQTTIRNYFLKYPLKVRQQVQFITMDMSGAYIPLARK
                     LFPNAKIVLDRFHIIQHLGRAFLKTRIAIMNQFDKKSLPYRALKNHWRLFQKDSRKLSL
                     NSFYSKTFRQTLAPHEVVAKTLVFSKELTDYYTLYQLLLFHFQEKRVDEFFELIEENRS
                     KVNHYFQTVFRTFLRHKQYIKNALETDYSNAKLKATNKLIKDIKRLGFGFRNFINFKKR
                     VFITLNIHKKRTYPVLSRC"
     CDS             complement(19336..19926)
                     /locus_tag="ctg1_960"
                     /transl_table=11
                     /translation="MNESTYKDAFGKEASQNATILTLKDHSDKNVEQTASRFMSLDGVK
                     GDVQNTTLKAQIKTIVNSLSRVMGVLIDVSILLAFVVLFNLTNINVAERIRELSTIKVL
                     GFFNKEVTLYIYRETIYLSIIGILVEFGLGLGLHQYMVDVIPPENIMFNPNLGWLIYAV
                     PTLVIIIILTGLGIFVNQHLKKVNMLEALKFVE"
     CDS             complement(19923..20078)
                     /locus_tag="ctg1_961"
                     /transl_table=11
                     /translation="MTEKGIIISEKLADLAGISVGDEVTVQNSQDKDIKLKVAGISEIT
                     WGTSSL"
     CDS             20330..21052
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     76.2; E-value: 4.8e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_962"
                     /transl_table=11
                     /translation="MRGRVSSYLADFSKLDNVYRFVEEIKRDFQRIDILFNNAGLYAGK
                     ERKASGENVELTFMLSVLVPYIFITELIPLLEKLPDGLVINTSSYMHHFAKVKDLDFGF
                     EKEYNPGLAYNNSKLYTIWMTRYLARDFFLKGSNTTINAYHLGLILTNLGNNSSDKKTE
                     KSLFGRLMKSLSKDLDQGIETGYYLTLSEEVSGLTGYYFDEKKVKSVSEKGYSFEKTQK
                     LMNYCQEKVKMFKEKQNV"
     CDS             complement(21229..21441)
                     /locus_tag="ctg1_963"
                     /transl_table=11
                     /translation="MLLLILLGIFTAFLSLAFALLHLMASLSELRKHKNTLGNRLLLIG
                     SNLATFSHPLLPFADCCFIPLADRS"
     CDS             complement(21480..22019)
                     /locus_tag="ctg1_964"
                     /transl_table=11
                     /translation="MTAQDRRITKTRKAIYQAFLYLLNQKDYEAITVQEIIDLADVGRS
                     TFYSHYESKELLLDELCQKLFHHLFERTQYLSPQDYLAHIFQHFKKNQDHVTSLLLSKN
                     DYFIRQLRKELEHDVYPMVADELIQSHPNIPHSYLKHLVITNFIETLTWWLKKGKSYSE
                     QEVVQFYLEILNVASN"
     CDS             22153..23049
                     /locus_tag="ctg1_965"
                     /transl_table=11
                     /translation="MSSKYAVWLAFFLNLSFSIVEFIAGGIFVSSAVLADSVHDLGDAL
                     AIGLSAFLETISNREEDSRYTLGYKRFSLLGALVTAVILMTGSGMVILENISKLFHPQP
                     VNDEGLLWLGIIAISVNLLASLVIRKGQTKNESILSLHFLEDTLGWLAVILMAIVLRFT
                     DWYILDPLLSLAISFFILSKAIPRFWSTLKIFLDAVPEGVDIKQVKNDLEQLDNVASIN
                     QLNLWTMDGLEKNAIVHVCLEHVKHIEVCKESIRDLLKESGFQNVTIEVDEDLATHQAH
                     KRNIEELEAESEQQHHH"
ORIGIN
        1 cacattcatt atttttttga ttatacaggg aaaatcccta tttggtttgc tatgattggt
       61 agattagcag cacccttgtt ccttttttgt gtgattgagg gttttattca tacccataac
      121 cggaagaaat acttcctaaa gatttattct ttagcaattg tgatgggact gattcaattt
      181 ggattctata attttctaca tcctctagtt agaccagatg gtttctttcc acaaaatatg
      241 atgctgtcgt cattcgcaat tttgctcgtt gctcttcaag ggattgcatg gattcaagaa
      301 aagaaatacc ttaaagggat accaacttta ctttttccat tgttgcttcc atggttaatg
      361 atgccttttt atctgctaag tgtgaacaaa cctatgtttg gttttctact aaatttactc
      421 aatttcacag tattgccagt ccatacattt atcagtgatg gaggaacgtg gttgcttttg
      481 accggtatcg ctatgtatct ttgtcatagg aatcttaaga aagaagtgct tgcttttatg
      541 agtgttagtc tcgtttggct gctaatggcg attgttttaa gtagaccttc ttttcacgat
      601 ttaatattca aatactttga atggatggaa atattttcag cacctttaat gctttcttat
      661 aacggtcaaa gagggaaagg gtcaaaatat ttgttctatg ttttttaccc aacccatatt
      721 tatctacttt acgccttgtc agttatcttc tatagatgat atgatatgga taactttgaa
      781 ggaaaggaaa ggctatggct cgaatacttg ttattgatga tcaaaaagat attgttcaat
      841 tggttgtaaa ggctttagag ctccaaaacc ataatgtgac agggcttaca agtgttttag
      901 atttggataa gaactcttta cctcgatttg acctgatttt actggatatt atgatgcctg
      961 atgttgacgg tctacagttt tgccatgaga ttcgaaatca ggtggattgc ccaatcctct
     1021 ttattacagc taaaacgcaa gaagcagaca ttgtccaagg gttgagttat ggtgcggatg
     1081 attacatttg caaaccattt ggagttaaag aactccaagc gcgtgttgca gctcacttga
     1141 gacgtgaaca tcgtgagcgt caccataagc tttcacttgg ggagtttcag tttgacttgt
     1201 ctgctcaaga gctttatatt gagaatcagt tgttagattt gacaaagtcg gaatatggta
     1261 tttgccagtt tttagctgaa aataagggcc aagtcttttc aaaagaacaa atctacacgc
     1321 atttgtacgg ctatgaggat aaaggcagtc cggcagcagt ggctgaacat atcaagaata
     1381 tccgtgcaaa gcttaaagaa gttgggcaaa atcctattga aacagtttgg gggattggtt
     1441 acaagtggca ctaataaaaa aacgagaaca ctctctaaga acaatcttgt tatcttatgt
     1501 cgtcagtctt acagttctct ctgtaatcag cagtcttctt attttgtatt tgttcagctt
     1561 gtcttttcgt tttggagttt tgattccagc aaatcaagtt gagagtgatt tgtctgctgt
     1621 gagaagtgat attgaaactt ctaaggtctt taatcccgag attttacctg atggcacgag
     1681 ttatgtcttt ttaactagag attttaagct taaaaagtct aacatgcctg ttaacttgca
     1741 agaagaatcc ttactaaatt accaattcaa gaatgctcac ggtgagaaat acggctattt
     1801 tcagtctttt gaacgatcag atggcatagt cattgtcaat tatcaactat cacctcggta
     1861 ccgtaatgag tggatgaacc agcattttcc caatgctgat cttatgatga ttggttcaat
     1921 gtttgtatct atcttaatca tatttattat tttaactttt tattatgcaa ataaattgag
     1981 tcagcaactt aaacctatat taagggttac tgaaaaaatt tcccaacaag atttggattt
     2041 tcaaacttct cagtctacaa ttaaggaatt taatcaggtt ttaagtggtt tggatcatat
     2101 gcgtatagca cttcgtgagt ctttgatgga aaattggaag gcagagcaag ataaacaaaa
     2161 tcagatttct gccctgacac atgacttaaa gacgccccta acagttgctc gtggaaatgc
     2221 ggaactctta gctatgacgt ccttggatga aaatcaaacg gacttgttag agcattttca
     2281 aaaaggtatt gcacaggttg atacttatgt aaaagagttg tcagaaatca acaaaatgag
     2341 tttgaagaag accctgacgc ttgaagaagt tccagctaag gaatttgttg aagacattta
     2401 cgatcaaacc ttgtcattag ctcaaacgaa acaaatcaat gtggtatttg acaagaagga
     2461 aattgcgaaa gaaagcatag gcaattggga taagtccttg ttgaatcgag ctattatgaa
     2521 tattgtttca aatgccgtag agcatacacc cagtggcagt cagttgctcc tgaccgctag
     2581 ggtagaagaa gatgaattca agtttatatg ccttgattct ggtcctggat tttcccttga
     2641 atctcttgaa aacgctactc agctatttta tcaagaggat aaaagcagac atagtcgcaa
     2701 tcatagtggc cttggtctga ctattgccaa tgatattatt cgtttacact atggtagtct
     2761 ttctcttgca aatgacaatg gcacgggtgg tgctaaagtg actatcattt tacccctttt
     2821 aaatacagat gactcctagt cgccagatga ggagtttttt gctatactac taagagtaaa
     2881 aatgaagaaa gatttgtggg agcaggattt catcttgttt ccgaagaggt attagtgtca
     2941 tgtctcaatc aaaagcagat tatattaacg tgattggagc tggtttggcc ggatccgagg
     3001 cggcttatca gattgccaaa cgtggtattc cagtaaaact ttatgaaatg cgtggggtca
     3061 aagcaacacc acagcataag acaacaaatt ttgcagaatt ggtttgctct aactctttcc
     3121 gtggagatag cttgaccaat gctgtagggc ttctaaaaga agaaatgcgt cgtttggact
     3181 ctatcattat gcgtaatgga gaagctcacc gtgtgccagc aggtggtgcc atggcggtgg
     3241 accgtgaagg ctatgcagaa gcagtgacag ctgaaattga aagtcatccc ttaattgaag
     3301 ttatccgtaa agaaatcaca gaaattcctg atgatgctat tacagttatt gcttcaggtc
     3361 ccctaacttc tgatgcttta gctgaaaaga ttcatgagct taacggtgga gacgggttct
     3421 atttctatga tgccgctgca ccaatcgttg ataaagcaac tatcgacatg aacaaggttt
     3481 accttaagtc acgctatgat aagggtgaag cagcttatct aaactgtcca atgaccaagg
     3541 aagagttcat ggccttctat gaggccttga ctacagctga agaagctcct ttgaattctt
     3601 ttgaaaaaga aaagtatttc gaagggtgta tgcctatcga ggttatggct aaacgtggta
     3661 ttaaaacaat gctctacggt cctatgaaac cagttggttt ggagtatcct gaagattata
     3721 tgggtccacg tgatggtgac ttcaagacac cttatgcggt tgttcagctt cgtcaggaca
     3781 atgcggctgg tagcctctac aatatcgttg gtttccaaac ccacctcaaa tggggagagc
     3841 aaaaacgtgt cttccaaatg attccaggtc ttgaaaatgc agaatttgtt cgttatgggg
     3901 taatgcaccg taactcttac atggattcgc caaacttgct taaacagacc ttccaatcaa
     3961 aatcaaaccc taatctgttc tttgctggac aaatgactgg tgttgaaggt tatgttgaat
     4021 cagctgcctc aggtttggtt gctggaatca atgcagcccg tctttttaag ggtgaagatg
     4081 aagttatttt ccctcataca acagcaatcg gtagccttcc atattatgtg acacatgctg
     4141 aaagcaaaca tttccaacca atgaatgtta actttggtat tatcaaagaa ttagaaggcc
     4201 cacgtattcg tgacaagaaa gagcgttatg aaaaaatcgc agaaagatct cttaaggatt
     4261 tgcaaacttt tatagatgct tgatgctaac ataaaaagcc ctcacaagag tgaaggcttt
     4321 tcgttttaga gaggagcgaa tagaaatatc gattagccaa agaatttctt agcgatttct
     4381 tgaccttgtt tgattttagc ccattgttga ggtgttgcca gctcattacc tgagtcacat
     4441 gaggcgaaac cacattggtg agagaggaag agacgttttt ttggaaggat ttgactcgct
     4501 ttttcaagca aatcgagaac acgttcttcg tcatctaggt cagtcgttta agaagacaat
     4561 agcccaaata caacttcagc tttactgtct ttaagggctt ccagagcttt gatatcacca
     4621 gctgtatcgc tatcccattc aaggaagaag cggtcatagt gttgctctgc caagaatttc
     4681 ttagcgatgt cttcgtaagt tccttcagca gcagaacgga tttcataatt accacgacag
     4741 ttgtgtgtcc aaaccgttaa accaagttcg tgagtatagt caacaacctc attattgata
     4801 gcaacaaatt catcggccga ttctgccaaa tcaccattgc cgtctgagta gaaacttgca
     4861 gggtttgatg ggtcaaaaag ttcccagagg cagtcatcaa attgaacgat tttaccacca
     4921 acagccttgt attcatctaa gaattcttta tagacattaa tcaaaccttt tttgagttct
     4981 tcgtttgttt catagacttg tccaggaaca gccaattgat caaagatagc aagttcagtg
     5041 taggtatgag caggtcccca gatagtttgt ttggtatctt catcaccagc ttcagcctta
     5101 accaatttgt aaatatctag gtagtggtgg tttttacctg agagaggctc agtgacacga
     5161 ataccgatat ctttacgtgt ttcatattga ccaccatcat ggtctttaaa agtataacca
     5221 tgctcagcaa tgtagcgttc aatacctttg agtccccaga caaagtccaa gtgccacata
     5281 gaacgtccaa actccccatc ggtaaggatg tcaattccgt tagctttttg gtcagccaca
     5341 ttcacttaat agatgcagtt tcagtttctt gataaccagg aagggcatca tagaaaggat
     5401 actggatgtc gtcacgatgc tcgatttcgt ccttgtattt acggagatcc gcaggacgaa
     5461 gaagagaacc gactaattgg aatttagatt ttgtcattaa atttacctcg aaatgtctat
     5521 ttacatctat attatctctt atgggaacta atgaaaaata gttaatttct tgctgtggat
     5581 atagttttag actatacaag gtttagctct gcaaaatgat acttcttatg ataaaatgga
     5641 aagaaaacga tgaaggttgg gaatatgcaa aaaacattct ttattattaa accagatgct
     5701 gttaaacgcc atctaattgg tcaagtgctt gatcgaattg agcgacgtgg cttcgttatt
     5761 gagcgtatgg agatgctgat gcttgacgaa gaacgtctta aagaacatta tgcccaattg
     5821 gctgataaac cttttttccc tagtatttct gaattcatga tgagtggtcc agcagttatt
     5881 ggtattatgt ccggcccagg tgttattaag tcatggcgtg atatgatggg agcaactaat
     5941 cctggggatg ctgctcctgg aacgattcgt ggagactttg caacagcacc agatggtgac
     6001 atgattccaa atatcgttca tggctctgat tcagaagaat ctgcggctcg agaaattaag
     6061 atttggtttg gtgagtagga tggatatagc acagattcaa tcagaattag ctcaggatgg
     6121 actattaatt gatgtcagga ctccagaaga gtacgcagaa ggtcatgtta aggatgcttt
     6181 attaatacct cacacgcagt ttttcacagc tgacattcca gctaaaaaag acgattcaat
     6241 ttatctttat tgtaaaatgg gatctcgtgc tgaatttgct gcaggtgtac tgaaagaacg
     6301 aggatatact aaggttacca ccttaggtgg cctaggtgat atggaagcac tagggtttaa
     6361 gtttgaaaaa taatacacat aaggtcacta gtggtgatct tatttgcttt caaaaagcat
     6421 gacaaattat taacaacgct tttataaagg ggtagaatct taattgagtt aagacaaagc
     6481 ctatgaaaat gactttgcca gaacttgatt aacttagcat attccaattg agatagggct
     6541 tgtggttaag cttgtgacta caattggtag aggaggattt cgtatgtcaa aagttgctat
     6601 tgttacaggt gcaggtcaag gtattggttt tgcgatttca aaacgcttgg ttgaagatgg
     6661 ttttaaagtc ggggtattgg actatgacgc tgaaactgct gaaaaagcag ttgttgagtt
     6721 gtcagaagac aaggcatttt ccgttgtagc agatgtgtct aaacaagctg aggtagcagc
     6781 agctttccaa aaagtagttg atcactttgg cgacttgaat gttgttgtta ataatgctgg
     6841 tgtgcaccaa caaaaccccc ttgaaactat tactgaagaa cagtttcaac gtacatttaa
     6901 cattaatgtt ggtggagtta tctgaggtgc acaagctgcc caagcacaat ttaaatcact
     6961 tggtcatggt ggtaaaatta tcaatgcaac tttacaagca ggtgttgtag ggaactctaa
     7021 cttaactgta tatggtggaa ctaaattcgt agttcgtggt attactcaaa ctttggcgcg
     7081 tgacttagct gattcaggta taactgtaaa tgcttatgca ccaggtatcg ttaagactcc
     7141 aatgatgttt gacatttccc acgaagttgg taaaatgctg gtaaagatga tgagtagggt
     7201 atgcaaactt ttgctaaaga tattaccctc aaacgtttgt cagaacctga agatgttgca
     7261 gcagcagtta gcttcctagc tggacctgac tcaaactaca tcacaggtca aacaatcatc
     7321 gttgatggtg gtatgcaatt ccattaaggt taaaagggag agcgaatggc tctctttttt
     7381 tgcttgataa aacataatgt ttctgataat atagttataa ataattatgt ttttaaaggt
     7441 ggattcccat atcagacatc ttacactata ttgctgagca cccatttttt agtcttattc
     7501 tattgggaat tattgtacta gcctttggtt tagctccatt ttcaagtagt tcaatagaga
     7561 acaagcgttc agctattatt aataagcact acaatgataa ttttaagaaa taagaaggac
     7621 taaatgcagt cataaagcag atattagaga taggcaaatg cctgtctttt ttgtataata
     7681 ggaggtgacg gttcgttttt taacaatcac aagtaagaac taggaaagaa taaaatgcca
     7741 aatattgaag aattaaaaca aagacaggag aagattcgca acttctcgat tattgctcat
     7801 attgaccatg gtaaatcaac gcttgctgac cgtatcttgg aaaagactga gactgtatca
     7861 agtcgtgaga tgcaggcaca actccttgat agtatggatc ttgagcgcga acgtggtatc
     7921 actatcaaac tgaatgccat tgagcttaac tacaaagcta aagacggcga gacttatatt
     7981 ttccacctta tcgacacacc gggacatgtg gactttactt atgaggtgtc acgttccctt
     8041 gccgcctgtg agggtgctat cttggtggta gatgcagctc aagggattga agcacaaaca
     8101 cttgccaatg tttacttggc acttgataat gacttggaaa tcttaccagt tatcaataaa
     8161 atcgaccttc cagcggcaga tcctgagcgt gtacgtacag agattgaaga tgttatcgga
     8221 ttagatgcct cggaagctgt gcttgcatca gctaaggctg gcattggtat cgaagagatt
     8281 ctcgaacaaa ttgttgagaa agttcctgcg ccccaaggtg atgtggaagc acctctccaa
     8341 gcccttatct ttgactctgt ttatgatgcg tatcgtggcg tcatactcca agtgcgtgtg
     8401 gttaacggaa tggttaaaac gggcgataag attcaaatga tgtctaatgg caagaccttt
     8461 gacgttactg aggttggtat tttcactcct aaagctgttg gccgtgacta ccttgcgact
     8521 ggagatgttg gttatgtagc agcttcaatt aagacagttg cggatactcg tgtcggtgat
     8581 acagtgacac ttgcggataa tccagccgca gaaccacttc atggttataa gcaaatgaac
     8641 ccaatggtct ttgctggtct ttatccgatt gagtcaaata aatataacga cttgcgtgag
     8701 gctcttgaaa agctccaatt gaatgatgcc agtcttcaat ttgagcctga aacgtctcaa
     8761 gcccttggtt ttggtttccg ttgtggtttc ttgggccttc ttcacatgga tgttatccaa
     8821 gagcgtttgg aacgtgagtt taacatcgat ctcatcatga ctgcaccatc agtagtttac
     8881 catgttaaca ctactgacgg tgaaatgctt gaagtgtcca acccatctga atttccagat
     8941 cctacacgta ttgataccat tgaagagcct tatatcaaag ctcaaattat ggttcctcaa
     9001 gagtatgttg gtgctgttat ggagttggcg caacgtaaac gtggtgattt tgaaaccatg
     9061 gaatatattg atgataatcg tgttaacgtt atctatcaaa ttccacttgc tgaaatcgtc
     9121 tttgacttct ttgataaatt gaagtcatca actcgtggtt atgcaagttt tgactatgaa
     9181 ttgtcagagt accgtcgttc acaattggtg aaaatggata ttctccttaa tggtgataag
     9241 gtcgatgccc ttagctttat tgtccataga gaatttgcct acgaacgtgg aaaacttatc
     9301 gttgataaac ttaagaaaat tattccacgt caacaatttg aagttcctat ccaagcggct
     9361 attggtcaaa aaattgttgc ccgtacagat atcaaagctc ttcgtaaaaa cgtcttggct
     9421 aaatgttacg gtggtgacgt ttcacgtaaa cgtaaactcc tcgaaaaaca aaaagccggt
     9481 aagaaacgta tgaaagccat cggttcggtg gaggtaccac aagaagcctt cttgtctgtg
     9541 ctttcaatgg acgaagatga gaaataagaa tgatagtaga atgtgatgtt ctggctattt
     9601 tagtaaaaag ttatgataaa gaggatttta aaatttacct tctcaaagtg acgtatagag
     9661 aatggcacca ctaatccaac atataaaaca ttggaagaaa ttgccgctgc aaccaatact
     9721 agattagttg ttgactttgt tccaataaag aactagtttt tgtatacact caaaaagctc
     9781 tataatctct acagtagttt tacccactac agaaattata gagcccttta ttttctattt
     9841 gtttagccaa cagcaattac aataatgctt tcaaaaatta gaagtaagat agctaaaaaa
     9901 ctttctttat tcatagaaat taacctccta tctcactata tgatataata cttttaagtt
     9961 tatctgggaa attctcgtat atgcaaaaga ggtgcttttt atgaaagatt atggaaaatt
    10021 atttaagaaa tttagagagt ctaggggatt agtcttaaaa gatatcgcaa agttaggcgt
    10081 atcagtatct catatttccc gctttgaacg tgaaaataca gatttgacaa ttagtaagtt
    10141 tatgtcagct ttaaatgcga taaatatgcc tattgatgag tttatgtatg cagcaaacga
    10201 ctttcagaga gatgagttta atgaaatctt agaaaagatt agtttatttg tttcagcaag
    10261 gaacgtgtca ggtatggaaa agttattaat ctctcaagta gaaaaaatcg aaaagcgtga
    10321 gactttttat actctaaata ctattttaat aaaaattcgt ttacaggact tatcagacaa
    10381 aagttactat gatgaatctg atatccaata tttatcagac tacctattct ctgtagaata
    10441 ttggggttgt tacgaactac tgttatttgc gaatactgta gatgtattga atcatcaaac
    10501 aatgatgctt ttatcaagag aaatgtgtaa acgttcagaa ttttacaagg atttaccaaa
    10561 ctaccgaagg ttacactcaa caatgctatt aaattgttat atcataagta ttgaaagaga
    10621 tgagtatatt gatgcgttgt attttgaaaa acagttaaat catagttgtt ttacggaaac
    10681 tgagatttac gagaaattag tgtttcatta ttcaaaaaat ttatatgaat taaagaagaa
    10741 taggagcaat aaagctattc tagaaatgaa gaagtgtatt gctgcaatga agctggctaa
    10801 tagtgagaat ttagctataa aatttgaaaa tcatttatct ggagtgttaa aaatgtagtt
    10861 ggatttgtgt atatggtata aattatcagt gtcaaaatta aatgatatat tattgatatg
    10921 agaattatta aatttcctga acagatttca gaagatatca ttcattatac gtttctagat
    10981 gatattatct cttataattg tgaaaagtgt agaggatctt gttgtcatgt gaataattct
    11041 ttattacttg atgcaaagac agcaagtttt ctaaaacgca cgtatcttaa agattttatt
    11101 gttagtgatg atagtgtttc attgttgagt tgtggtaaaa agtgctggtt tcattctgaa
    11161 ttgggttgta cgataaatga tttaggcttg aacaagccat taacttgtga attatatcct
    11221 tttcatatta agaaaattca gaacttctat attgtttctt ttactccttg tccgacattt
    11281 caactgaacc ttggtgaggg gcagaggtac aaggatatag aggatgtagt tttacgatat
    11341 attaaaactg gggtgccagt ttttagtccg tctttgcatg tttcagagga aaggctgaaa
    11401 tatgagattg agtatcaaaa caattttaaa aacactttat cagagtatta tcgaacaaag
    11461 actgccgatg gcactacaga gtttaaagaa tatgaaaaat ggtatatata ttatttagat
    11521 tttagatggg gaagtatacc cttatcttat acaagttcac aagcaaatca attttggaat
    11581 ctttacaaga gagtttgtga agatgtttat aaaaaaatat catatatacg aacagataac
    11641 atatacttta ttattgcaaa tcagtttaat aagacaattt caaagcattt tcagctaaat
    11701 tttatagata aagaatgatt tctatgattt gttatgggta cttattgatt cttaaataaa
    11761 taatggagga tattacgatg caagttagtg atgctattgc acaaattgaa ttagcagaag
    11821 aagaagttgt ttctagcggt ctatctattg acattatgga aattaaacct tctgttgcta
    11881 cagagttgat tgatggactc aaaggtcgtt gcccaccgtc tgtctaatag aactgattgt
    11941 aggattagag tctatctcta atcctttggt ttttatatta atatttttgg aagattgcag
    12001 ggaattaata tgacgagcaa tgtttactcg atttttttta attggtacaa taagcaagga
    12061 atactcagga ataataggaa taataaacta ttttcattaa atttagctac atttttagct
    12121 ttaaaattta tgtaccaatt ttcattgaaa aagttttctg attcaaagag tcaggtaata
    12181 aaaaatgtta tagattttct aaataacaat gaaatatcac tctctaagac caacactaaa
    12241 attgttgaat tttcaacgaa aataccatta aaagtgatac agattgaggt cacgaacaaa
    12301 tgtaacctaa gatgtatgca ttgttattta cctgattatt caaaggagct cgatagaaag
    12361 aaaatttcaa gtatagtata tgaagctaag cagctaggag taatggatgt tgatttcact
    12421 ggaggcgaac cattattatt acagggatta agtggaatta tcgaggaagt attaaaagag
    12481 ggaatgtgta caacaatttt tacaaatgct gtatatattc ctgaagattt taaaatattg
    12541 attcaaagat atgatggtat aagactaaaa gttagtttag atggttggaa tgaaacaata
    12601 catgattcaa ttagaggaag aggtacattt aagagaacaa ttaagaatat tgaatatttt
    12661 aggagtttag gagtacctgt tactgttaat gttgttttga ataacaagaa tattagtgga
    12721 gtgaagtatt ttttggagtt gtttgatcga ttagatgtga aatatgcttt tgataggttt
    12781 ttaccttttg aaaggaataa tcgactatca attagtgatg aagaattcaa taatgctatt
    12841 ttgtgtattc ccaatattca agcaaattgt aataatatat ccgaatccac atttgaatca
    12901 ttttattgtg gtgctggcaa ttcttatgtg tttataaatt cgtcaggtga tgttggattt
    12961 tgtccgacat tatcctccac taaattttgt ggaggtaaca ttaatgaaaa gactttaaat
    13021 gatatttgga ttaattcgaa gttcttcaat catattcgaa atgtacgatg taagtattat
    13081 aatgaatgcc ctgcaaatta tgtttgtcaa ggtgggtgta gaagtcgagc tcagtttttc
    13141 ggaggttcta ttgggagtcc cgatatacag gagtgcaagt tagcatataa tttaactggg
    13201 attaagccaa agtcaatgag tttatgaaaa tattatctat tatttatgat ggtggaagta
    13261 gaattccagg agcgagattt gctcccacaa aatattatca agaagcgatg ttatatgata
    13321 ggaaagattc tgatataatt acaattaatt taggtaatca agatttattt tctattgatt
    13381 tagaaagtct aagtcgaact attgctgaat ctaaagttca gattgcttta ggaggagatc
    13441 attcagttac ttatctatta gcaaaggcca ctgttcgaga gggagcatat ttaattgttt
    13501 tagatgctca tttagattac ttcaaagact ttgaaagtgt tgtaaaaaat tggaattttt
    13561 taagtttttt aaccgatatt tttgaaaaaa taattatcat tggggaaagg aattttgagt
    13621 ttcctagttc atttgataat aaaataatca tcctctcaat ggaggagtat tggttaaata
    13681 agagtagagt tttgaaaaag ttagatagtt atattgatga gtcaaaagat atttacttat
    13741 caatagacat tgatgttttg gatccatctg tttttgattc agtatcatat cctattattg
    13801 gaggatttca aatgaacgat tttcttggaa taatttccaa aattttatgt tctgataagg
    13861 tatatttttg tgatatagtt gagtacaatc cgatggttgg aagtgataat gctcacattt
    13921 tttaccaaat gattcaattt gttaaatcaa aattaaggag gatataggaa atattgaaaa
    13981 caaaaaaata tgcagcattg agtatttatt ttaatcgttt ctcatcgtta atctcagagt
    14041 atggttatac tatcttgatc aacattctat tgtctagaat ttctgtgcaa ttagttatgt
    14101 atttttgggt ggtaaagtgt ttagctgcaa tagttacaaa taggattaat atctcaaata
    14161 gtaaactgag cagaaaatac ctgcttattc tgttagaaat tacaaaggca atcttacttt
    14221 tcttactagg ttttggatta aaccatataa ttgtcctatt agttgtattc ataattgagg
    14281 ttgtcaatgt attgttttcc agtttattat atagttgtgt accaattatt atagacaagg
    14341 attcattgat taagtttaac gctaggtata caagcattgg ttcagtatct tattttttag
    14401 caccgttgtt tgttggttta tttattaata aaagtcactt tttattgttt gcagtttatg
    14461 ctcttctttt gatagtggga gctactagtc ttttattttt accaaatatt tcgactttaa
    14521 atttgaaaga agaaagaaaa aaacaaaatt taaacattac attatttaac attctgagat
    14581 ccaaaaaaat tgcattagtt ctattatctg gagttattgt gggatcaatt ggagttgttt
    14641 atgatactta tgaagttgtt tatttaacaa agtatctcgg tattagtgat tctatgtatt
    14701 ccttttcctt atcattttta gcagtttcat tcttagtaat gagcttcctt cttagcttcg
    14761 tgaaacaaat aagttctcat atgaaagctt tcgccttagg tctttcattt tatgttctat
    14821 atctactttt atttagtaca tcttcgaaca tttatacagt actaatgagt tatgtttttc
    14881 tagcgatagg tcagacaatg atggggataa tcgaaaccaa ttattttcag ttgtcactta
    14941 acatgaaaga attacagaaa ctatatattt actcggagac cttacattct gtattttcag
    15001 gcattgctgt tttagtaata ggaagttttg cctttttaag tagtcatctt gttttagttt
    15061 tcagaagtct tgctgttttt gctctgttta ttcttctgtg ttattgtgtg tttgtaaacc
    15121 tcaaaaaact aagcattgat aagtaatatt tataaatcag aaaacaagca aatgagatag
    15181 ttaatttata aagtagacaa acgctatttt gagtgtttgt ctttttttag tcacctagtc
    15241 tgcctttttt cacaagattg tctgaaaact gtgctataat gataacagaa ttgtgaattg
    15301 atgaaagttt gtgaaaaaac gagcagactt tgacactttg tgacttatac ttgaaaggaa
    15361 agttggctct accattttag ggctagaagg actgtgttca tgtcagaaga aaagcaattg
    15421 tatggtgcag atttagtggt tgatagtttg atcaaccatg atgttgagta tgtctttggg
    15481 attccaggcg caaaaatcga tagggttttt gataccttgg aagataaggg acctgaattg
    15541 attgttgccc gtcatgagca aaatgctgct tttatggctc aaggtgttgg acgtattact
    15601 gggaaaccag gtgtagtatt ggtaacatct ggtccaggtg tctccaattt ggctactggt
    15661 ttggtaacag cgacggatga aggagaccct gttcttgcta ttggtggtca ggttaagcgt
    15721 gcagatctct tgaaacgtgc ccaccaatca atgaataacg ttgctatgct tgagccaatt
    15781 accaaatatg ctgctgaagt acatgatgct aacacccttt ctgaaacggt tgctaatgcc
    15841 tatcgtcacg ctaagtcagg gaaaccaggt gcaagcttca tttcaattcc tcaagacgtg
    15901 acggatgctc cggtcagtgt taaggctatt aagcctatga cagatccaaa acttggttca
    15961 gcatctgttt ctgatattaa ctatctagca caagccatta aaaatgcagt gttgccagtc
    16021 tttcttttgg ggaatggtgc ctcatcagaa gccgtaactt actctattcg ccaaattttg
    16081 aagcatgtta aattgccagt tgttgaaact ttccaaggtg ccggtatcgt gtcacgtgac
    16141 cttgaagaag atactttctt tggtcgtgta ggtcttttcc gtaaccaacc cggagacatg
    16201 ttgcttaaaa aatccgactt agttattgcc attggttatg acccaatcga atatgaagca
    16261 cgtaactgga atgctgaaat ttcagcacgt atcatcgtta ttgatgttga gccggccgag
    16321 gtggacactt acttccaacc ggaacgtgaa ttgattggta atgtagaagc gagcttaaac
    16381 ttgcttttgc ccgctattca aggttataaa ttgcctgaag gttcggttga atatcttaaa
    16441 ggtttgaaaa acaatgttgt tgaggatgtt aagtttgacc gtcagcctga tgaaggtacg
    16501 gtgcatccgc tagatttaat cgaagttttg caagaacaaa cagatgatga tatgactgtt
    16561 acggttgatg ttggtagtca ctatatttgg atggcacgtt atttcaaatc gtatgaacca
    16621 cgtcatttgc ttttctcaaa tgggatgcaa acgctaggtg ttgctcttcc atgggctatc
    16681 tctgcagctt tggttcgtcc taagacaaaa gtgatttctg tttctggtga tggtggtttc
    16741 ctcttctcag cacaagaatt ggaaacagca gttcgtttga aattgccaat tgtccatatt
    16801 atctggaacg atggtcatta caatatggtg gaattccagg aagaaatgaa gtacggtcgt
    16861 tcatctgggg ttgactttgg tcctgtagat tttgtaaaat atgctgagag ctttggagcc
    16921 aaaggttatc gtgcaacaag taaagcagcg tttgctagct tgcttcaaga ggctttgact
    16981 caggctgtag atggaccagt ccttattgat gttccaattg actatagaga taacattaaa
    17041 ctcggcgaaa ctattttgcc agatgaattt tactaaaaag agggtgtaga catgtctgaa
    17101 gccataaaat tatttcaata taatactttg ggagccttga tggctgggct ttatggaggt
    17161 actttaactg ttggagagtt gttagagcat ggagacttgg gcctcggaac attagattct
    17221 atcgatggtg agttgattgt tcttgacggt aaagcctatc aagctaaagg ctctgaaggt
    17281 aaagtcgaag tggtagaagt ctctcctgat gaaaaagttc cctatgcagc agtcgtacct
    17341 caccaagctg aagttatctt ccgtcaacgt tatgaaatga ctgataaaga acttgaggat
    17401 cgtattgaat catactatga tggggtcaat cttttccgtt caatcaaaat caaaggtcat
    17461 tttaaacaca tgcacgtgcg catgattcca aaatcaaatg cggacattaa gtttgctgat
    17521 gttgccactc gccaacctga gtatgaggta gatgatattt caggtacaat cgttggtatc
    17581 tggacacctg aaatgttcca cggtgtgagt gttgctggtt accatctcca ttttatttca
    17641 gatgacttga cattcggtgg tcacgttatg gattttgtta tcgagaatgg tattattgaa
    17701 gttggaccag ttgaccaact cgatcaacgc ttcccagttc aagaccgtca atatctcttt
    17761 gctaaattca atgttgatga aatgcgtaaa gatattacta aggctgaata agcatataaa
    17821 taagatactg tctctttgtc aactgtagtg ggtaacgaaa agctaacatc tagagaggac
    17881 cggataggtc ctttttttat gtatgttcag tgtgatgaag acacgcttct taaagttgat
    17941 aaagtttcta aaaccgaagc ccaaacgttt gatgtctttg atcaacttat tagtagcttt
    18001 aagtttcgcg tttgaatagt ccgtttctag tgcgtttttg atgtattgct tgtgtctaag
    18061 aaaagtccta aagacagttt gaaaataatg attgaccttg ctcctatttt cctctatcag
    18121 ttcaaagaac tcatctactc tcttctcctg aaagtgaaaa agcaaaagct gataaagtgt
    18181 atagtagtca gtaagctctt ttgaaaagac tagtgtcttc gcaacaactt catgtggtgc
    18241 taaagtttgg cggaaagtct ttgaataaaa agagttgaga gatagtttac ggctgtcctt
    18301 ttggaagagt cgccagtgat ttttcaaggc tcgatagggt agtgacttct tatcgaactg
    18361 gttcataatt gcaattcttg tctttaaaaa ggcacgtcca aggtgctgga tgatgtggaa
    18421 acgatcaaga acgatttttg cgtttggaaa gagcttgcga gccagtggaa tataagctcc
    18481 agacatatcc atcgtgataa actgtacctg ttgtcggact ttcaatggat acttcaaaaa
    18541 gtagtttcgt atagtagttt ggcggcgatt atcaaggatg gttatgagtt cgtttgtctc
    18601 ataattctgc gccacaaaag ccaattcccc tttcttgaac ccaaactcat cccaggacat
    18661 aacagcaggg agtttgtcat aatgtttctt gaaagtgaac tgatcaagct tacgatagac
    18721 agtggacgtc gacacgcgaa gtcttcttgc aatatcagtt agtgacactt tctcagttag
    18781 gagttgtgta actttttgtc ggactagatt ggagatttgg cagtttttct caacgataga
    18841 tgtctcagct accgtgactc ttctacaact tttacactgg aaacgacgtt ttttcagacg
    18901 tagtagagtt ggtgttcccg cttgctcgag aagagagatt ttagagtttt tttgaaagtc
    18961 atacttaatc atctttccat ggcaatgagg acatgatggt gcagggtaat caagttttgc
    19021 ttgaatctcg atatgagtgt cagtttcaaa aacaagtgaa atcttgatat tttggtcttt
    19081 gattccgatt aattctgtgt tattcttaat aagtctcata agttcttcct aatgatggtt
    19141 tggtcgcttt tcattatagt tcttatggga ctttttgtgt acactcaaaa agctctataa
    19201 tccctacagt agttttaccc actacagaaa ttatagagcc aagatactcc cctattcgac
    19261 ataggggagt atcttgtttt aaaacgacga agtggtccta actcttccgt tttatttatt
    19321 aagttatagc atatctcact caacaaattt tagagcctcg agcatattga ctttcttaag
    19381 gtgttggttc acaaagatac ccagacctgt cagaatgata atgattacta gtgttggaac
    19441 agcgtagatg agccagccaa gatttggatt gaacataata ttttcaggtg ggataacatc
    19501 taccatgtat tgatgcagtc ccaaaccaag tccgaattca accaagatac caatgataga
    19561 aagataaatt gtttctcgat agatgtagag cgtcacttct ttattaaaga aacctagaac
    19621 cttaatggtt gataattcgc ggatacgctc tgccacattg atattcgtta aattgaagag
    19681 aacaacaaaa gcaagaagaa tagaaacatc aatcaaaact cccataacac ggctaagtga
    19741 gttgacgatg gtcttgattt gtgcctttag agtagtattt tggacatccc cttttacacc
    19801 atcaagagac ataaatcgac tggctgtttg ctcaacattt ttgtctgaat gatctttcag
    19861 tgtaagtatc gtagcatttt ggctagcctc ttttccgaaa gcatccttat aagtagattc
    19921 gttcataaag atgaagtgcc ccatgtaatc tcagaaatac cagcaacttt gagtttgatg
    19981 tctttgtcct ggctattttg aacggttact tcatcaccta cagaaatacc agctaggtcc
    20041 gccaatttct ctgagataat aatgcctttt tcagtcaaat caagcttctg accagtttca
    20101 cgatgattga gtttgatgta attttgaagt gttttttgat ctttatcatt gataacaagt
    20161 gttgtgatat cttgacgatc gttattactt cctacatcta acaggtgcta cggacggtat
    20221 cggtaagcat ctagcaaaga aaccgtctag tgaaggctat catatcatcc tccacggtcg
    20281 caatcctcaa aagctggaat tggctactca ggaggttcgg gcagtctcct tgagaggcag
    20341 agtgtctagc tacttggctg atttttcaaa attagataat gtttatcgat ttgtggagga
    20401 aatcaagcga gactttcaaa ggattgatat cttatttaac aatgcaggtc tgtatgcagg
    20461 gaaagagcga aaagcgagtg gtgaaaatgt cgaactaact ttcatgttat ccgttctggt
    20521 tccctatatt tttataacag agctaatccc cttgttagaa aaattgcctg atggccttgt
    20581 tatcaatacc tcttcctata tgcaccattt tgcgaaagtg aaggatttgg actttggctt
    20641 tgagaaagaa tacaatcccg gtttggccta caataattcc aagctctaca ccatttggat
    20701 gacacgctat ctagcaagag atttcttttt aaaaggttca aataccacta ttaatgccta
    20761 ccatctcggc ttgattttaa ccaacttagg gaataattct agtgataaaa agacggaaaa
    20821 gtctctcttc ggacgcttga tgaagtctct ttcaaaagat ctagatcagg gaatcgaaac
    20881 aggctattat ctcaccttat cagaggaagt cagtggcttg actggctact actttgatga
    20941 aaagaaagtc aagtcggtat ctgaaaaagg ctactcattt gaaaaaacac agaaattaat
    21001 gaattactgc caagaaaagg tcaaaatgtt taaagaaaag cagaatgttt aatatcataa
    21061 atataagaaa aaagctcaag ttttcattaa taaaacttga tcttttctta tacaagagtt
    21121 aataaaatcg taattaccag agcgattccg atccgaatca ggtagtgggc tactagatgg
    21181 aaatttcctt tatgcttgcc attccaatag gctccgtagc aaatcaagct aactccgatc
    21241 agccaaagga ataaagcaac aatcggcaaa aggaagtaaa ggatgagaga aggtcgcaag
    21301 gttgcttccg ataaggagaa gccgatttcc tagagtattc ttgtgctttc ttaattctga
    21361 aagactggcc attaaatgaa gaagagcaaa agcaagggat aagaaagctg tgaaaatacc
    21421 aagaagaatg agaaggagca tagttttcct ttctatgata catgatgtaa agtcgcacct
    21481 tagttagaag cgacgtttaa aatctccaaa taaaactgga ctacttcctg ctcgctgtag
    21541 gacttgcctt ttttcaacca ccaggtcagg gtttcaatga agttggttat aaccaggtgc
    21601 ttgagatatg agtgaggaat gttggggtgt gattgaatca gttcatcagc taccattgga
    21661 tagacgtcat gttccagttc ttttcgcagc tgccggataa aataatcgtt ttttgaaagc
    21721 aagagactgg ttacatggtc ttgatttttc ttgaaatgtt gaaagatatg ggccaggtag
    21781 tcttgtggag agaggtattg agtacgctca aacaaatggt gaaagagctt ttggcagagc
    21841 tcatccagta gtaactcttt gctctcataa tggctgtaaa aggtcgaacg ccccacatca
    21901 gccaagtcaa taatctcctg aacggtgatg gcctcataat ctttttggtt aagtaagtac
    21961 aagaaagctt gatagatggc ttttctagtc ttggtaatgc gacgatcttg tgcagtcata
    22021 tggacactat gaacaaactg ttcagtaacg tacacagcga acggtttgcc cctatccttt
    22081 ctgttggtag tattggataa tagatattga atatgatgtt cgtgaatcta ttataccaaa
    22141 ggaaggtaaa aaatgagttc aaaatatgca gtctggttgg cttttttctt gaatctaagc
    22201 ttttccattg ttgagtttat tgcaggggga atctttgttt ccagtgctgt tctcgctgac
    22261 tctgtccatg acttggggga tgctctagcc attggcctct cggcctttct agaaacaatc
    22321 tccaatcgtg aagaagatag tcgctatacc ctaggctaca agcgttttag cttattaggg
    22381 gctttggtaa cggcagtcat tctgatgaca gggtctggta tggtgatttt agaaaatata
    22441 agcaagcttt tccacccaca acccgtcaat gacgaagggc ttctttggtt gggaattatt
    22501 gctatcagtg tcaatctgct ggctagtctg gtcattcgta agggtcagac caagaatgag
    22561 tctattctca gcctgcattt tttggaagat accttaggtt ggttggctgt catcctgatg
    22621 gccattgtcc tccgatttac ggactggtat atcctagatc ccctcttgtc tcttgctatt
    22681 tccttcttta ttctgtccaa agccattcca cgtttttgga gcacgctcaa gattttcctg
    22741 gatgctgtgc cagaaggggt agatatcaag caagttaaga atgacttaga gcagttggat
    22801 aatgttgcta gtatcaatca gcttaatctt tggaccatgg acggcttgga gaaaaatgct
    22861 attgtccatg tttgtctgga gcatgtcaaa catatcgagg tctgtaaaga gtctatccga
    22921 gacttgctca aagagagtgg ctttcaaaat gtcaccatcg aagttgatga agacttggca
    22981 acccaccaag ctcacaagcg aaatatcgaa gagctagaag cagaaagtga gcagcaacac
    23041 catcattaag gtttgttttt aaactcttag agtctacctt taagagttat tttgatacca
    23101 agttccctaa agtgatcctt ttcatgataa aatagaacaa atgtagaaca aggattaatt
    23161 atgagtaaga gagctgtgtt gatgatgacc tttgggtcac cagaagagat tacctatgaa
    23221 ggagtag
//
