LOCUS       gnlProkkaGEEKBGBJ_14   17083 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEEKBGBJ_14.
ACCESSION   gnlProkkaGEEKBGBJ_14
VERSION     gnlProkkaGEEKBGBJ_14
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 22:01:22
            Original ID  :: gnl|Prokka|GEEKBGBJ_14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17083
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17083
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4657:7083]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4658..7083
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..17083
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17083
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             548..649
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MEEVRKLRQEKAELEKDNDFLKKAAAFFAKEID"
     CDS             1248..1547
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MCTASFGIAKEAYKFRKNLITKEEFLLNSQILCVEVSVSALSSIL
                     GHAVIPIPILGSVIGNNIGTFLYEIAKDNLTMKEKLLIADYFKEIQEYNYFLDN"
     CDS             complement(1647..2558)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             complement(2788..2877)
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             complement(2874..3476)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_5"
                     /sec_met_domain="TIGR04085 (E-value: 2e-15, bitscore: 49.8,
                     seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.5e-12, bitscore: 39.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERISKGE
                     FKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGVRAC
                     SINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLKSITFDDISGKCSECP
                     LPWCGGGCRCSALELDGTLLGSDLACFYEQKGGGVVV"
     CDS             complement(3570..4661)
                     /locus_tag="ctg14_6"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             complement(4658..5977)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_7"
                     /sec_met_domain="Streptide_RRE (E-value: 1.7e-24, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.5e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.2e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.4e-13, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNAFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             complement(6047..6139)
                     /locus_tag="ctg14_8"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             complement(6229..7083)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_9"
                     /sec_met_domain="TIGR01716 (E-value: 8.1e-50, bitscore:
                     162.2, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFGEIFKKFRESRGLRLKDVAKAGISTSQLSRFEKGETDLTIS
                     KFMFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGMKKLLYSQMELED
                     RREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYYELLIFSNTLDVL
                     NHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFMDALYFEKQLNQC
                     FFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSHHLAKTYEGHLEK
                     NFS"
     CDS             complement(7323..8159)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 265.8; E-value: 6.2e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg14_10"
                     /transl_table=11
                     /translation="MVTEFSLDMLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIF
                     TKHKGNYGYRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAE
                     NLIQRQFEASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQV
                     KAMLEQAFTEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESF
                     FGILKSEMFYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             complement(8153..8719)
                     /locus_tag="ctg14_11"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             complement(8898..9056)
                     /locus_tag="ctg14_12"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             complement(9068..9199)
                     /locus_tag="ctg14_13"
                     /transl_table=11
                     /translation="MNIEECKQISILDVANRLGISFKQVYDKAVYWIYSGVKGQYEY"
     CDS             complement(9209..9721)
                     /locus_tag="ctg14_14"
                     /transl_table=11
                     /translation="MAAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQ
                     PYMTESAYSQELTSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSD
                     LKNANQSKTNQTETRTVNLNYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPS
                     LPNTTTK"
     CDS             complement(10121..13300)
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 497.2; E-value: 1.7e-150)"
                     /gene_kind="other"
                     /locus_tag="ctg14_15"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDHFQKSLEERLRQSNKDMEKRQAQLDGHFASQVWSE
                     EELSVLEQTPASEKLTRLEEFLSQRQENVTKQKSILKAAHEDLAQLQKSLQTAQDLAKI
                     FQELEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     EIAQEALSEKQQAFEDVKAKKEELTVQSKDFLQKEEELETWKENIIYAQSLAQEQEKIK
                     RSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLDSLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLIIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVAKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIHKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             complement(13297..14505)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.5; E-value: 8.1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_16"
                     /sec_met_domain="Metallophos_2 (E-value: 7.5e-10, bitscore:
                     31.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEKVDGVII
                     SGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFFQHQGLH
                     LSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYILEDMEKA
                     FDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFDYVALGH
                     IHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLEVKRPIV
                     ALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTDIVEITF
                     SRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESVFEEIER
                     SRQ"
ORIGIN
        1 tgacttaagg ttaaaagata tggcagacaa agtttatcag ataattgacg gtaaaatgac
       61 aatcctggag aagtaattta atttatgact aaaaatcagc aaaaatataa ttatgactaa
      121 ggaatatttt attaactaaa tgttgagata gcacaaggaa atatttgtgc tatctttttt
      181 atttattagg aaaagagaaa aaattatgcc aacgaaaata tggttaaaac cagaacaatt
      241 agatttgtat attaaacatt tagaacgatt tagagactta tatagtaaac tagactgttc
      301 tggtatagta aatttgtaac actcctacct aataagttaa actattcatt agaataggag
      361 acataacatg aaacactatc cagacgaaac acgataaaaa attgttcgac tgcacattca
      421 agacggatga acattaaaaa gcttagctgc tgaatatggc gtatcccaag cctcaatctc
      481 taattgggta agacattatc gcaaagaatg ccaaactaat aataaagaaa aatcacagct
      541 tgaactcatg gaggaggttc gtaaattacg tcaagaaaag gcagagcttg aaaaggacaa
      601 tgatttctta aaaaaagcag cggcattctt tgcaaaggaa atcgattaga ggcatatcgt
      661 tttattgata actataaaga agattttggt ttgcgttggt tgttcttgca tatgaatatt
      721 catcccaatg cttattataa ttatcttaaa aagacaagga ctaactatca tcgtcaaaag
      781 aaagctattc ttaatactat tcgagatatc taccatgagt gcaatggaaa gaagtaaatc
      841 aattcttcga aacagaaagc atcaaacttt ctgatataga gccttcgaaa gttagttata
      901 gggaggtaca aaggaatcaa atcaatacca ctatttataa tgaaaaaggt aatataaagg
      961 atattgatac tagcattata agagatatgt acgataaaag caaacctact ttaaaacagg
     1021 gagcctatat atccgctata gcagcttctc tagaaggggg gtactgcatt tataacagca
     1081 ataattaaaa aaagcgctta gggaaaacta ttagtgagtt tacaaaagac gattgtcttg
     1141 aaatttctaa agatagtgga attggagcta taaaaggaag tactcgaggc attacgatat
     1201 acgccctaac gaattacaca gctactcctg cagcagtagc aagttcattg tgcactgctt
     1261 catttggtat cgctaaagaa gcatacaaat tccgtaaaaa cttaatcaca aaagaagaat
     1321 ttttactaaa ttcgcaaata ttatgtgttg aagtatcagt tagtgcatta tcctcaatat
     1381 taggacatgc tgtaattcca atacctattt taggatccgt tattggaaat aatataggaa
     1441 ctttcctata tgaaatcgct aaagataatc tcacaatgaa agagaaatta ctgatagcag
     1501 attatttcaa agagatacaa gaatataact attttttaga taattaattt gaattatata
     1561 atcatcaact tcagagagat taagaattac tataaacttt tagggaaggc attttctcct
     1621 gactataata tcgcttttca gggatcttat gaatttttaa atatgttttt taaaaatacg
     1681 ttaacctctc ctattttctc tgcttcaggt aaatagatag aaacggttgt cgaataaaca
     1741 aaagaaggta cactcacaat tgaaagcaat tgactaataa ctgcataaat agccaacaat
     1801 tctactccta atctcgacat caaggcatca aacaccataa taaacaaaac actctccaga
     1861 atttcttgac caaccaaagg aataccaaat gttattaatt caaatttagt tgtagatgta
     1921 atggataaag ccttcaaaat cattggataa accataaaca agtaactaag cgatatgaaa
     1981 gctaaggata caatcgttga tatggctgct cccttaattc cgatttgtgg taccagtaca
     2041 taatttaaca caacatctat taatgaactg ataagtccaa cccacataat tggttttgtt
     2101 ttcttttgaa ctcttaataa atttgtcagc gaaaagttta ataatgtcaa tccgatatat
     2161 ggagacatga agactaaata aatggtggat aaggacaata gttgcccttt aaatccatag
     2221 agctgcttca agattacatt tccaaaaata atgacaaaaa ccgcaaaggc aactccgata
     2281 attaaatcta aggttagatt tgatttcaat aaatcatcaa acctgttagt ttgccgatta
     2341 gagtacgcct tagagctttt aatattaaat gacaaactga atgctcctaa aagtccacca
     2401 aaagcaaata agagattctg aataatggaa attcctgaca gagcaattga ggaattgttc
     2461 acagcaaaat gcaatgctat ctgcccaata attacttgac caatatttgt taaaactaag
     2521 ggaaaggcaa atttgttaat ttcttttgaa tctatcattt ttcctctcta aaaggcttca
     2581 aatgtaagta aagatcagat ttaactaaat ttgcataaat aatatgcaaa ataggagttt
     2641 cttctaaaaa tgaaataatt gcctgcttac aatcattagc agatacctca taatcttgct
     2701 gtaatagttc tacaatcttg tctaaagaaa aatttttaga aatgcaataa agtatttctg
     2761 ctcctatttc atcaaatgaa tagtactcta atcaagtaga tcgtatccta tgtattcatc
     2821 tgctacttta tttacaatga aatctctctt acctcttatc acaaaatgtt ctttcatacg
     2881 actactccac ctcctttttg ttcataaaag caggctaaat cagagcccag taatgttcca
     2941 tctaattcca aggcactgca tcgacatccc ccaccacacc atggtagggg acattctgaa
     3001 catttcccag aaatatcatc aaatgtaatt gattttagtt tattaaatac agcagaatgg
     3061 tgccaaattt cgctaaactt ttgttcttta acatttccag caactaattc atctatacca
     3121 ttcatcaagt cacacccgta tacatctcct ttatgattaa ttgaacatgc tctaactcca
     3181 gcttgacaag atatttccct tggcttatca aaatttatat ctactttttg atgccaaaca
     3241 ttttctaata aatctgatct attataaaat gcaagcggaa aataatgtgt caaaaaaaca
     3301 tcactttcat taggaggaac aattttaaat ttaactttga actctccttt agaaatccgc
     3361 tctgttaaat caagaaaaac aggataccat tgttttttat ctgctaaaat actaccgtca
     3421 ttagccctac cagtaggaca aataaccata actgacatat actcaatacc aagcatatca
     3481 ttcaatctta tactctaaag aaaatatctg ctaaatttgc aaacaattgt gctatcaata
     3541 atttggcaaa tgaattagaa atacaacttt taagttcttt tctctctgtt agaaaatgaa
     3601 taagatacta agcaacaaag agctactata ccaaatatta aataattgct cctaatacta
     3661 aagttatcag caaaaatacc agctaggaaa tcagctaaca taaaactaat cgaaataaac
     3721 aaattatata ctgaccatga tactgctcta tttttttcta ttgacatatt aaatttataa
     3781 taaaaatgat tattgtagtt ggaattaaga acacgcatta ataaaaggat tataatttgg
     3841 atgattagat tagtttgaaa aaacatgagt atagctaata ctggtaacat caagcttact
     3901 tcaaacttaa tttttagata actccccaaa gccatagata tattaaacat aaatagtata
     3961 attcccagca tatctagtga aagtccctgt tcatttaaga atatccctgc ataagaattg
     4021 ctaatcataa ttagagttga gaatgctact cctaatatta ttaataacca tggaatattt
     4081 tgaatattat cgaggctaaa aaatttttgt ttattatttt gttccttttt aatctcgggt
     4141 aatcctatta aatataataa actgaaaatt acaaatacaa tggatataat aataggataa
     4201 atataattcc tatgcaataa aggtggagat ataatcgtaa taatagcaat aaaaatatat
     4261 tttaatgtgt tgagattttt caaaaatgat ttatatacaa cttcgtcatc aattatttca
     4321 aaattataag aaataagaac tcctgaagat aatgattctg acaatccaaa aaatatcgct
     4381 gaaatatata ttatatttga ttttccaaac aataggcccc ataatgctaa aattaataat
     4441 aaatttgaaa tagccaaaat tttcttgtaa ccaatcttac ttgaaatata acttaaagga
     4501 atatcaaaaa ctgagccaca tagctcagta ataactgata aagtagctat ttctgtgaac
     4561 gaaaaaccta agtgctttaa tagtaaaatt cctacaaagt agtacggtaa tccagataga
     4621 aacatattca ttccgtataa attaaaaatc ttcttactca taagttacaa actgggtctc
     4681 taaaatattt tggactcttc tccttaatca agttaacata gcagccaccc tcgcaaattt
     4741 ttaacaatcc acaagataaa cacttagaat tcttcgttct aaaagaacga atccctccat
     4801 acaacggatc atcataccaa acatctaaca aatctttttc aaaggcattc tgcttagttt
     4861 gattaactcc taaaaaagca atgcaaggca agatatcccc attagacatt atttccatct
     4921 tagtatattt tgcacgacat ccataataca tttcgccaaa ctctgaaaat tcaattgaat
     4981 tatttatcaa ctccggataa gcggtgaaaa gatgacatcc ctcagtagca aaatttaaat
     5041 tagcttcccg ttgagttata taatctgtaa catactcatt caaccttctc aaatcagcta
     5101 aatcgtattt tttctttatt ttcgtatatc ctgttacctc agaataatta gctactgaaa
     5161 atctatctat tttattctct atacaaaaat caaccaattc tataatctgc tcatagcttt
     5221 gctttgtata cactgcatta attctacatt tttttccaac ctctttaaag tacttcgcta
     5281 atttaatttg tctatcaggt ctcaccccca ttaattcaaa atttaattta ggatctaaag
     5341 tctgcaaaga taaaaccggt gtaatatatt tagatttagc tagaatttcc actgtacttt
     5401 tctttattaa ttgggcatta gttgttatag tagtctttat cttcagttct tcacaagcta
     5461 tcaacaaatt atcaatatca aaatatctag tcggttcccc tcctaaaatt gaaacactta
     5521 acactccatt atcttttgct tggcgcaaaa ttctttccca atctttagca ggtttggcat
     5581 ttctatcttc acgatttgct aaaaaacaaa aaccacattt taaatcacag tacatactgg
     5641 ggtatattac tagttcaagc ggaaaactca atatgttatg tttttttaat tttgctacat
     5701 gctttctcgc attttgaaga gtctcgtcag gatttttcga tgatccctca atattattat
     5761 cagaatagat atttaataag agtactcgct ctagtttccc tgcttttatt tctttcttaa
     5821 aaaaggacgt agcaatttca aaaccatgat tttgaaccaa ataaagaaaa taagcttcac
     5881 tctcatctaa ctcaattcgg tcaaaagtta ctttatttat caaaattcca ccaaactttt
     5941 ctagtctaaa taaaaaatct tctgaaattg tcatcatatt gaataccttt ctaaaaaagc
     6001 agaggaaaat atagcctctg cttaacttat gggataaatt actttatcac tcccagccgt
     6061 caccttttgc catcaccttc cagccgtcac cttttgccat tgaactagac tcaaggactt
     6121 tttcaagctc tttagacata tttggtactc ctttcgaata tgatactgtg attatatttc
     6181 ttttcaacac ttacaataaa atattcccat atttgcattt tctaactact agctaaaatt
     6241 tttttctaaa tgtccttcat aagtctttgc taagtgatga cttcctgcta atttcatcgc
     6301 tccaacacac ttcttcattt caataattgc tttcacattt ccatcctctt tatattgata
     6361 aagattttgt gcatacttaa agactaaacg ttcatatact tctgtctcaa taaaaaagca
     6421 ttgatttagc tgcttttcaa aatataaagc atccataaat ttttctcttt caacacatgt
     6481 aatatatcca tttaaaagca tcgttgaaat taatcgtctg ttatttggaa tttctttgta
     6541 aaaatcagaa cgcctaaaca tttctcttgc taagaccatg aaaacatcat gatttaatac
     6601 atctaaagta ttcgagaaaa tcaataactc atagtacccc cagtattcta cactaaagag
     6661 ataatctgtt aaatatgtca aatcatcctt tgtatagtaa gtttctcctg ataaatcctg
     6721 tagacgaatt ttcaataaaa taatattgat ttgatgaaat ttttctcgcc tatcttccag
     6781 ttccatctga gaataaagta attttttcat accttctacg tcacgtgttg acacaaaatg
     6841 acgtactttc gataacagtt cgtttaactc atctctatga aaatcatgga ccgcatacat
     6901 aaattcatct attggcatat tgatttcatc taaaataaac atgaactttg aaatcgttaa
     6961 atctgtttct cctttctcaa atcgagagag ctgagacgtt gatataccag cctttgcgac
     7021 gtcttttaat cgtaatcctc tcgattctcg aaacttttta aaaatttctc caaatttttt
     7081 catactacac ctccatcacg catatatggg aataattttc atttgctttc atcatatcat
     7141 acaataaaga aaaacaaaag tgaggattat cacatgaaaa agcaaatttt actaacactt
     7201 cttcttgtcg tatttgaaga cattatcgtt atcgtcgtgg gataaagagt ctgggacaaa
     7261 agtcctttag ctccaaaaag caacggcata atgtactgac cccaaaaagt tagacaaata
     7321 atttaagtaa aggatttagt tctgtattgt acaggactga gtccttttag ttttacctta
     7381 atgcgtttgt tgttgtaata attaatatag tctgcaattg cttgttccaa atgctcaatt
     7441 gacttaaacg tcttctcata accataaaac atctcagact taagaatgcc aaagaaggat
     7501 tccatcatgc cgttgtctgg actattgcct ttacgtgaca tggatggttg gattcctttc
     7561 tcctctaaaa aatgatgata gaaatcatgt tgatattgcc atccctggtc actatggaga
     7621 attgtatttt tgtaatgttt ctctgtaaag gcttgttcta acatagcttt cacttgtatc
     7681 aagttcggtg acttagaaag attgtaggcg ataatttcac tattgaagcc atctaaaatt
     7741 ggcgacaaat agagtttttg gctgcttgct ggaatggcaa attctgttac atctgtgtag
     7801 catttttcca atggtttgga tgcttcgaac tggcgttgga tgagattctc tgctttcata
     7861 ccaacctctc cttgatatga agaatactta cgtttacggc gaattctagc ggttaaacca
     7921 agtactttca taagacgttg aactctctta tgattaatca caattcctcg atttctcaat
     7981 tcaagagtca ttcgacgata gccgtaattt cctttatgct tagtaaaaat ggcttgaatt
     8041 tcagctttaa tgtcataatc cttatcattt tgatccagct gttttaagtg gtaataatag
     8101 gttgaacgag caagcttaat aatctttaga agcatatcta aagaaaactc agttaccaat
     8161 cctcggacaa tttccgtttt tcttcttgct ctttttcttc cctcaatcgg agttctctca
     8221 actttttaag aactgcattc tccgctctaa ggtactcatt ttctgcttga agacgttcca
     8281 tttcttccag ttttttcttt ggcttacgtc ccattttaga taaccttcct cttgttttct
     8341 caacaatagt atacccgttt ttcttatagt gtgcgagcca gttaggaagc gtcccacgat
     8401 ttgggagagc atattcaaga gaaactctat cttgagaata gcctttatat aggactttat
     8461 caatcatttc ttgttttaat tcaggagagt agtaacgatt ctttcctttt ttagcgattt
     8521 ctattccgta tcgatcaatc aatttaatca tgtagctaag attagaaatg tttatcccaa
     8581 atttatttga aagctgatct aagctatatc cttggtttct aagttcatag atttgaacct
     8641 tatcttcata agtcaatttc ataataaaaa caccccgaaa gttagatttt ttctgtctaa
     8701 cttttggggt gcagttcata aaaccgttgc tttttgcatg attgtgatag acttggtgaa
     8761 atagaattga ccaaaaatct tctgaaatat aacaagagag tgactcgaat ttaaaaagct
     8821 agagttccac aattggaaat ctctagcttt tttgtgactg agaacttttt gtcccagcct
     8881 ctactttcta ctgactacta tcctgcatgc cctaagtcga gatagagaat atctcgctta
     8941 gtggcatact ctagcgcatg ttcaacagcc tcaaataaat ctgaagctag aaaccttttc
     9001 gtaaagacgg tttcgtcttt acgcttaaat ttcgcaacat aactatgttt agtcattttt
     9061 tctccttcta atattcatat tgtcctttaa caccactata gatccagtaa actgctttat
     9121 cataaacttg tttaaaggag atacctaatc gattggctac atcaagaatt gaaatttgct
     9181 tacattcctc tatattcata aaatatcatc attttgtcgt agtattcggc aatgatggaa
     9241 cagatgagga ttcttctaaa gttttaggag ttgccttatc tagatcatct aacccagatt
     9301 tccaaacctg tacttggttg accaataact taccaggtag tttcgaatag ttcaaattaa
     9361 ccgttctggt ttctgtttgg tttgtctttg attggttggc attctttaaa tcagatacat
     9421 aagttacatt ataagagacc atggcaatgg cttgattcgt agtctgattg acaaagatat
     9481 ctgctttttc aaaatgataa tccaaaatat agtccttata cacttggttc atggcatcat
     9541 tttgacttgt caattcttga gaataggccg attcagtcat ataaggttga atacgtgtat
     9601 tattttcccc tagtttttct ttcgtatagt actgtgtcaa aaattctttt acagtatctg
     9661 atgataaaat acttgcttta tcttctgctt gtttgtcctc tacaagttta gctgcagcca
     9721 attcgatttc ttttcgactt tgtttggcag tagaatgttg accaatagaa ttagcagtaa
     9781 gttgtggtgt tgatgaggtg gatatactaa aaaatgagga ggaaattgat aattacttca
     9841 cctagctaaa agttcaacga attagggaga cattaggtag cctcatatta ctttgattag
     9901 tttttgctat aacattgtca aatatgatga caaaaaaatc cgtccgcact tttttacgag
     9961 taggacgaat taaatatgtt atacaaacca tcagcttttt aacaattcta cataaggtag
    10021 ttgttgatgc aactaccttt tttctatgct gattagaaca aatttgacat ggctacaact
    10081 gcgattatct gatatagagt attatataaa ctgattcctc ctacccctta tccacaattt
    10141 taatacggct actgccatcg tgcgacttga tgataactag ttgctgagca ataccttctt
    10201 tcatatcgtc tacgtggctg atgacaccga ccatgcggtt ttcaccgatt tgttccagaa
    10261 cagaaatggc cttggtcagg gcttccttat ccagtgagcc aaacccttca tcgatgaaga
    10321 gagcttcaac aacggcaccc ttgctggtat tttggacaac ttctgagagg gatagggcaa
    10381 tggccagtgc agcgataaag gtttcaccac cagacaagga tttaacggag cgttcactac
    10441 ctgtcagctg gtcatagacg ttgatatcca aaccgaagtg atcacgcgcc ctgcgtcctt
    10501 cctcacttag aacaaaggaa tagcggttat ccgttaatag tccgatgtag ttagcattgg
    10561 catagtccaa gatttgttgg aaatactgac ggataacgta gacctcaaga ttaagacgac
    10621 cagttagagc agtattttct cccttaacca ccttaaccaa atcactgagt tcttggtggg
    10681 ccttaaaggc ctcttggtta ctgtcttgaa gggttttagc cgcttggtag gtagccgtcg
    10741 catccttaag tcccttttcc atgacagaaa actgagcgag ctgcctatca tagatttcct
    10801 gacaattctg tactgcttgc gctagactat cgagatctgg ttgttcttga ttttggagaa
    10861 gctcttgccc cttatgaatc tgcgcctgta attcttgttt gagcgttgca taggtcgtta
    10921 atttggcctg aagcatagga atagcttgat tatttacctc aataagccag agttcgacct
    10981 gctctaagtc attagcgagg gctccttcag ccttgagact ttgctctaat tcagcagata
    11041 atcgcttaac atcttgattt accttatctt tagacttagt tatactctca atctgcccct
    11101 ttattccttt aatgtcggca tgaagttggt tgtaggcttc gctattttcc ttgacttgct
    11161 tattgtagag gttcagctcc tgatgagcaa gggaaatccg ttcttgatat acctcaacag
    11221 actcaagttc tggatgagct tcctgcaggt cctctaggcg ttcttgagct tggtcaagca
    11281 ctgccttggc ctcttgatag gttttagcca aatctgtcgc ttttttttga gccttaccta
    11341 gctcatcttg atatcggata taatctgtct cttccttatc ataacgtttt tgtaactctt
    11401 gataatactg ctcaaccttc aggagtaggg cttgcccacg gtcagtttca tagtctatcg
    11461 aaaaatcaaa atcaaaccgt cccttaacgt gctcttctaa ttcttgatag tgcttttcaa
    11521 gagttgcctt gactttagcc acttggtcaa gcaaatcctg acgtttagat gcaacttcac
    11581 tcaaggtagc ctgacgattt gataaagtag cgacttgctt ttctttttga gcttgaagct
    11641 tctccacctg atccatgaga tttttcaagg ccacttcatc agcctgtgct ccaccaacat
    11701 tagggtgttc cagagcacca caaaccatac aaggatgccc ctcctctaac tctgcctgca
    11761 gttggacaat aatgagttga cggcgtgaaa ccaaagtcct tcttaactcc tcttccaatt
    11821 ctttgagaat ttcttgagct tgatcaatat caaaagataa cgtttgatga cgtttttcgg
    11881 tctttgtcaa ctcctgattc aagttctcta tttctttcag gtcctgagca agttgattct
    11941 ccacactgta gcccacaatc tggaagagtt tttcggcctc atgtaaacta tctaaactaa
    12001 gacgattagc ctccaagtca gacaaggact tgttaagcat ctcaacctct tttctagcct
    12061 gctgataggt ctcttccaac tgcttgtagt tagtcgttga acgtttgatt ttctcctgtt
    12121 cttgggcaag actctgggca tagataatat tctctttcca agtttcaagc tcctcttctt
    12181 tttgaagaaa atccttagat tgaactgtga gttcctcttt tttagcctta acatcctcaa
    12241 acgcctgttg cttttcactt aaggcttctt gagcaatttc aaggtcctgc tctaattgca
    12301 tcaactgttt ccgatactgc ttcaaggtcc gaatggtttc ctgcagacct tgagcaaact
    12361 gtaattcctc cagatgcact tttgcctctg cctgtccttg agccccctcc tcaatttcca
    12421 gacggtaacg ttccttggct tgctccaatt cttgaaaaat ctttgccaaa tcttgggcag
    12481 tttgcaagct cttctgcagt tgtgccaaat cctcgtgggc agccttcaag atactttttt
    12541 gcttcgtaac attttcttga cgctgagaca aaaactcttc aagacgtgtc aatttttcag
    12601 aggctggcgt ttgctccaag acggataatt cttcctcaga ccaaacctga ctggcaaaat
    12661 gaccatctag ctgagcctga cgcttttcca tatccttatt actctgacga agacgctctt
    12721 ccaagctctt ttgaaaatgg tcaaaaatac ccgttccaaa gattttcttt aaaatttgag
    12781 tcttggtctt agaatcttct ttcaagaaac ggctgaaatc attttgtgga aggagaataa
    12841 tctgtttgaa ctgctcagca ttgagcccca aaatctgctc aatctggtca ctcacttcct
    12901 tgatcttatc cccaagcttt tcaatttcct gaccaccaat cttatccaca atgactagag
    12961 aagccgtcgc cttttgcatg gtagtgcccc caccctgctt ggccctctct tgctggagaa
    13021 ctcggtcaat gcgataaagg tgattgcctt gttggaaata gaaagtcacc ttggtcaaat
    13081 catcctctgg accagcgaaa gttgaccgca tctcctcaac attacgatca ccactggtcg
    13141 tagcaaacaa ggctaccgtc atggcatcaa agagagtact cttaccagcc cctgtatccc
    13201 ctccaatcaa aaagagggga gcatggtcaa actgagtgaa attaataact tccttacgat
    13261 atggtccaaa attggtcaat tctaactgga ctggtctcat tgtcgactcc tctcaatctc
    13321 ctcaaaaaca ctttccacaa gggcagtctg tctctcagat aagacatcgc ccccagttac
    13381 tgtctggtaa aaatcaaata cgatttcctg gggcgactgc atttccaaat cttttaagtg
    13441 ctgatcaacg gtcaagtttt cttccctaac atcacccaga cgactgaaag taatttctac
    13501 aatgtctgtc ccataaatct cttccagtcg ggcacgcaca ttgataccct ctaattcctt
    13561 acgactagac agttgaatat caaaggcgaa ccaggctttt tgacaaggtt gattcttata
    13621 aaattcaggt gacatcaagg tttcaaaaga ttcctgtaaa gccacaatcg gccgtttaac
    13681 ctctagagta tggaaggtct gagacatatc accagacgca tccaattcaa gaatatagac
    13741 acccttttct tccttacgct tggcttcttt gacattaaag gcgactggac tgcctgaata
    13801 ttgcacgcgc ttggtaggac tagcaaaacg cgtatggata tgccctaagg caacataatc
    13861 gaaagacttg aaaaggtcac tggtcacatt ggtaagacca cctaccgtat tactggtttc
    13921 agacaacatc aattctcgaa gaccctgacc atcgctatca tccttcttag aaaccgcaaa
    13981 atgcgtcacc aagacatgag ctttgtcagg atcaaaagct ttttccatat cctcaagaat
    14041 gtaggtcaag gcatcaccaa tcccctgaat ttcctttccc tcatcatcct tatagtaaat
    14101 acgagcatca ataggatcga taaaaggcag cagaaaaatc tggcaattct ccaactcaat
    14161 gggctcaaaa gcctcctcca aacgtgtact taaatgaagg ccctgatgtt gaaagaagtc
    14221 acgcccaaaa tgtaaacgtt cagccccatc gtgattacca ctaatcgcat agacaggaat
    14281 ctgctcctcc agtaccaagc gggccaaggt cttattaaaa agcttaatcg catccacagg
    14341 gggcaccgca cggtcataga ggtccccaga aatgataacc ccatccactt tttcgctaat
    14401 agccaaatcc acaatttgtt gaaaagccca ctcctgctcc tccaacaaag accagccatt
    14461 gagggttcgt cctacatgcc aatctgacgt atgtaaaaac ttcatgacaa cctcctcatt
    14521 cattttgtct tacttctatt gtaccttatc aagctaaata ctgcttaaaa gtttcacagg
    14581 ctttgatagt tttcccgttt tttagctgta aagatcaaaa aatctctccc aagctatcct
    14641 gtactgaccc caaaaagtta gacaatttat gtaagcaaag gatttagctc tgtattgcac
    14701 aggattgagt ccttttagtt ttaccttaat gcatttgttg ttgtagtaat caatatagtc
    14761 tagattaccc tgcctcaatt ggttaagtaa tttaaatacc tctaaccaag aaaatcaata
    14821 ttatctattc ttttaattga cttttataga ttctaagcat tatcatatag gttggtacta
    14881 gtgcacatct tgtattttag gcaataatat ttactcactt ttcgttattg tcagtaccga
    14941 tcctttttaa atttttcact atgaaaacct aaaaataatc cgaaccctaa gggctcctga
    15001 ctttttactt tattctaggc tttttttatc cgtggcttgt tagctgactt ggaactaggc
    15061 atgtagtatt tactatttcc ctacttgaga ttttttataa gtcacatgca ttattccatc
    15121 tgaacgaatg gtatgatttt tatttctttt agagaaacac cggtaatagc taattcctat
    15181 cttaaatcac ttgaaatata tttataatgt gttggagtgc taatcagtac cgcttgtaga
    15241 tttttggaag atactaacac actaatgatt taatctcctt taaaacatga aaagagaagc
    15301 ctccaaagct tctcttttat aattatcaaa taatgtacaa ctagattctt aataactacc
    15361 taatttagtg gttcaatcat gaagcttaat tgatagctat ctgctgagct aagcaagaat
    15421 tcgtcatgaa ctggagcacc ccatgtgtcg tcaccaccta cacccatttg agcagcaaga
    15481 actttaatcc atgtagcatc agattcttgc aactcatatt ggtgacgagc attttcaatt
    15541 tgttcagtac tgttacgcaa agcactgaat tcgaatgctt tattaagtgc ggtgaattta
    15601 agaccattat ggttatcatc agatactgtg aattcacgag taccatagtg attaccagat
    15661 tcttgtggca ttagatatgg agcaaatgtc ttttcaacag atgtttcata tcgaccaaga
    15721 taggcaccag gaagtttatc acggtagctt tcttctgcac cgtatccata atagctaagg
    15781 tttgtaaatt gtgaaccgat agcaaattct agaccaaatt cagggaagtt tggcaaacct
    15841 gctttaccat catagtttgc agtaacaaag attcgaccct tgtaatcaac ttgataagtt
    15901 accttaactt cgacatcaga caagcctggc aattcatgaa cataagtcac tttaacagag
    15961 tcgtcttcga tttgaatttg agtatctgta actttactat agtttccagc aaccttccag
    16021 cctgccattt cgaatggata tccagcacca cgatcgttgt cagtgtaagc acgagtgaag
    16081 ctaagtttag gacctttctc aatgaattca acaccattat acttagcaga tactaaagta
    16141 ttttgtgcac gtgaaagcaa gattgagaag ttttgtcctt gaataccgat gttgaagtcg
    16201 ccttcaacaa cattcaaagg tgctttaact ggtgtttcag tgctaatctt ttcaacaaca
    16261 tattgaccac gaacaatttc atgaccttta ggagcccatt cagttgcttc cctcagaaca
    16321 caagcaactt cgtaaatttg ttcagaattt gaagcctcga ctacaaagtt aactgggaat
    16381 gttgcttctt cgcctggttt aacatcaaag tgatattcac tttcactaac ttttctacca
    16441 tcttcgtaaa ctctagctag gaaagtataa gcagaaagat cttcgaagag attatcattc
    16501 ttgatagtta ctgatttttc atcaacagca atcttaatat tagagtaaag atgtttaact
    16561 gtttgaagtt ttggagttag ggtacgatct gcaaagacga taccatttcc acaaaattcg
    16621 tagtcagaag gtctatcatg ccagtcacca ccatatgata ggaattcgct accatttgga
    16681 agtgttttgt aaatagattg gtcaatgaag tcccaaataa atccaccttg gtattctgga
    16741 tatttctcta agtcagtgta gagttgcaat ccaccaccag agttacccat tgtgtgcatg
    16801 tattcacatg aaatataagg tttttgaggt ttgttagtta ggttacctga agcaaagtgt
    16861 ttatcactaa cgcttgaaag atcaactagt ttaccagttg tgaggtattc ttcgatatca
    16921 gctggtttcg catacatacg actttcgatg tctgtaatgt aatcaaactc acgacaccat
    16981 gcaacacctt catagtgaac tggacgagta ttgtcaacac tacggaagta atcagccatg
    17041 tcagcaatat ctttaccagc atatgattca ttaccacaag acc
//
