LOCUS       gnlProkkaPFDKEMBL_22   23813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFDKEMBL_22.
ACCESSION   gnlProkkaPFDKEMBL_22
VERSION     gnlProkkaPFDKEMBL_22
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 22:21:25
            Original ID  :: gnl|Prokka|PFDKEMBL_22
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 23813
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4064:13813]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4065..13813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..23813
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="chemical_hybrid"
                     /product="lanthipeptide-class-i"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..23813
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             complement(211..621)
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MPFPKAVAVRNTNDFYFQPQLNKLRMAAPESLRSIYIPKLGLDSY
                     LIHIDSVPGWRYSHDPLKIDYIYLISDNFESDVDLLTFIQYLLAQATMSDSSYVTTLVH
                     IFNLLQAPPFLVDIRNHEKMFQLLHTHHLPTY"
     CDS             complement(753..1091)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MNYQQFFSFWNSTLSVSSNNKPIIEQLSYIYKPEIVSNVGDSEVT
                     YYIDIHSSTGENALLFGENIENGLIDVSYGKSRNDLKTWKSNTTILPPISLAPLVNAFT
                     FIHGCALY"
     CDS             1225..1485
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MLIISIILIDFYSGFVKDYWIMVLFGKDSTIRSLNKIYLFHIFSP
                     KKPNSMIEFGILPLSTRSVRRDDHYLRIKMTLRIIPLLLLT"
     protocluster    1336..23813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[11335:13813]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      11336..13813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     CDS             complement(1534..2307)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S41"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="Peptidase_S41 (E-value: 5.1e-09, bitscore:
                     26.6, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKYSYVLGDGKIPDFLAKFGLITRIGEDDDLILINSFPKMLHKV
                     TRIMKVNGMSPIKKGSWHIGINTIQNENGEIFTIPLMPLDPKSIVYPPLINNHFVMMQI
                     LTFNVSQFAELYGVISKRRTLILDLRYNFGGEISAMSKCFEWLNAHCINQKVVLLFNNT
                     TASAAELFIEKCQRSNLSTVSIGSETYGKKWAYKKVTVGKSNFFLPIYQLAPQIEINEY
                     INTDTFYESSRSSDVQSKLIFPFALNIENILLERR"
     CDS             complement(2304..3899)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 134.1; E-value: 1e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_5"
                     /transl_table=11
                     /translation="MYILVKKQFIYHVKNTKLVVLLLILSVSVGSATYIQFLKGQMFQQ
                     AVSSKSSQLLVSFLLFALVMTLEVSFYYVEWQYENKLVSETFFELKKSVLSTVTKFKPY
                     KQASSDKEATQLLTNSIDSLEYPYYNAWFDNLYLSLRVIFVFVAVASINWIIAIIILAL
                     MFIPLGVTQVFKENISKLNKKYMDQVGVNLKKYEDIISNILPVHIFNLRSFVLKNAQAS
                     LETERNLKRSSKGKQYTLNASYSFISYFSSFVVLVFSLLLVSHGKLGLSSVITLLGLVD
                     QLSMPILSLSRNSSSINSTKAVRTDIDQYVLQNASANRKSISFSKKISLENVAVQLSNQ
                     EVSYRDMQFDFGHSYIIRGKSGVGKTLFLHLLTGLQPYDSGDIVYDNAPLGQAADKNVF
                     QDIRFVQAENTLFNGSVLENIFFDRTPSDDKLALCAKLLKKSTLNSADAASISTGEKRR
                     VLLLRGLLSNSRTLIFDEPTANLDANTSAVFWDMLFDWFNQGNRTMIIVSHTIDETNLN
                     RFDKQLDFNSLIKS"
     CDS             4065..6902
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     183.5; E-value: 8.3e-56)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_6"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.3e-13, bitscore:
                     39.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.4e-12, bitscore:
                     36.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILKHYMTRTAVNSPSNPVSQKVFNDMLYAASADVYQMAKKEQ
                     HTSLERKTLANYYARSIYRTTPFGLFSAVEFHNRDSETNKECHAVQYLVKPIIKSEATY
                     KITTLLSKTHFKELKLFKNDNVLEKSGDTLLNVFPIVDKRKDVIEKSIDYNFLIQQILE
                     KIGDDGITFNSLITDFRGIFPEYLLTKIISILIDSHFVLTELEDEQAYTDPNVLINKID
                     SLDIKVPLFVKDYFSFKEMTLEEFSTKAAEDVNQWFYSQFGTKKAVSYLLEADASQRYD
                     SAEYDNKILRFCNFLKKHSALIPSAEFESDYMWIVDHYGSAKIPLSSLRERIFEDAFLN
                     EHISKNASNAISRKIRSNYQKYINTNNIPLKELFKDVENTDTDSLVDPTFQLCFNISQS
                     GTLQLSPTIGTRGIGSIEGRFSRINPKEFREIIIQKNKYLKELGVTPVTVKLLNVPRFF
                     SLTSDIVDGSDLELSINLIGTGRDVVKLDELYVQAINGQILIFRKRKSDFELIKVEANN
                     MANWRKIYPPIIQKMFLWSERYFRNVLFPLDIIIKEQKEKVHNPAVFFEDILLLCENWN
                     PIIEIGEGLDRKSFTSNIKNFIKKYSIPKKVALVSGDQHILVSLNELGISQLWSEYKKI
                     GAFTLENNPMFLEISSKNESNNSTNLTEYILNIVNSTNNGREEKAYSQYVFTNDEIVAE
                     NLVWTEYDIYLPKTHQDTFICSAFDMIRNSLSIRKTFFIKYFDQRSHIRLRVQATERQK
                     EKLWFWLLKCYRNNVICDVVIRLYIPETSRYGAGNQLKRIHEFFCQDSCEIVENVLAEE
                     MSRDEKLQVALLLLLDIITASSTTQLDEIPVVNNKLLKKNKHIWREDWDRIKANISDSP
                     LTDRSVEKKSAPRFRALKAYFNNFNSTNNIDKLFAIQSLIHMTINRVYGIKAEEEGELN
                     YFLSKIIAKYRFKQK"
     CDS             complement(6976..8541)
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="MQKKVGENYMESEDRQTRKSNLRLLFEALVVGLVAGIVVGSFRWL
                     IGQTLAMWQKGYQAAHANPALLWLLAGGVLASVIVAGFLVKQQPHAGGSGIPEVELQLQ
                     GKLQLAWWPIFWRKFVGGVLSIGSGLFLGREGPSIQLGSTVGQGVAQGFKASKSDSRVL
                     LATGAASGLSAAFGAPLGGAMFIVEEVFHNFSPRVWLNALAGAIMANFVVSNVFGQTPV
                     LAIDYKHSFPIFQYWQLLLLGAFLGLIGRFYQWGLLNFSHVYQKIPVLPRWLHGIIPAL
                     ILVPIMYYFPGYVGGGNNLILSLNQIHAVNVLVLIFLLRISFSIVSYDSGLPGGIFLPI
                     LTMGALLGAVYGQFMVDLGLLDQKLVVNLIIFSMAGLFSAIVRSPFTAIMLIAEMVGSL
                     LHLMPLAVVSVAAYVVNELLGGVPIYESLAGRMQTKEDNDYVGEADQLTVSIYEGSQLA
                     DHQVKDIAWPDRTLVRVIHRGQKDIIPNGNTKLLAGDLLVLEIDENQRGLVYDKMARLQ
                     EAKE"
     CDS             complement(8594..9388)
                     /locus_tag="ctg22_8"
                     /transl_table=11
                     /translation="MSYPVFICDDDPDQIVQVTDTLKRAEQILSDEEKIRFDLASQGNY
                     QDAKAYLLSHPADGGIYFLDVELDQEVDADNGFDLAELIKKQDDRAQIIFLTSHADLSI
                     ITYRRRLGPVDYIVKGADPMAQRRRIVETVEVALDQLHKDSVAKQLAFSYRVGRQIKNI
                     RLTDLVYITTTLTPHKLLIVKQAGEAQFLGSLSQCAKENPLLEKISQSCLVNPDNIEAI
                     DLRRHLVSFVNGDVEEYGAGRQKQMKTLMQEHAYRLAELMKP"
     CDS             complement(9385..10740)
                     /locus_tag="ctg22_9"
                     /transl_table=11
                     /translation="MTLFLQILVMIFSAVVDIWLFCLFAQIKPGKLDWLLLLALEAVLS
                     VALSNFQTYSSLIYETGLEILLFCGYFYLLKKAGRFRQLLGAGLLFGIISLVIQLSMKV
                     LVSLLPLPSYFYFDAFMNLLLPLAALALLIWQRQRITSLLTDVNSGILVSLLAYLYIVC
                     CAIGAYILDDKKPTEVVLLFFFLLIFQAIFLAVIYREIVHIQRQLLDQQKQEALARQKQ
                     LLVKENEQLKEYADYLDRNEDELRRFKHDYQNILLSLKVSAEKGGSHALVEELEKYTSS
                     QFDQKALRKYPDVNHVKIPELKSIAIAKLAKLYNEKIDYSFGCEPEISQIPQTNLLDLV
                     RIIGIAFDNAIEASQQLEALGGQGRVEAMYYQEGGDFEFMIRNRIGGPVVDSDQLAQAG
                     YTTKEAHAGLGLANVKEIVSQHDEQMLLDYGPEDGWFNFSLTLLPENVEEEI"
     CDS             complement(10813..10962)
                     /locus_tag="ctg22_10"
                     /transl_table=11
                     /translation="MQVLDLQQLGNAGGAGLEDSKSFSLICIGSRVGDGNHSSHKKHHK
                     GKKH"
     CDS             complement(11336..13813)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_11"
                     /sec_met_domain="micKC (E-value: 1.9e-133, bitscore: 436.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8e-16, bitscore: 48.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 8.6e-11, bitscore:
                     31.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYQAQDYQPYLQADSDYYELDTTEKSDQEFTCSPPADWQNFYQG
                     DWHCCLSPRPLAQQGWKIHLSVALRQEQGMLDLVSHYCFAHLSSFKVTRSRRAWLLKNA
                     KYADRAASGKFITIYPEDEGEFVQTVIDLAALLKDFAPGPYILSDRRWQASPVYYRYGA
                     FKEIVKEISGQKCCCLQAPDGSWQEDQRCPYYYQPDFVQEPAELVRDNFQVKGAEISKL
                     TAYQIKEALHFSNGGGVYLAQKNGKNYVIKEGRPAAGLDGHGQDAFSRIQKEAGWLKKL
                     ANVPEVVDGKEDFQAWIHAYLVEDYVSGQTLGDYVAENYPFYPEKRAAYVAKSLQIAEK
                     LRQAVAHVHAQGVAIGDLQADNVMITEDGEVKLIDFEAAAELAQPYDPGIMTAGFSDLA
                     LENYEQADLYALYQSIRSIFLPISNRARASWPMQDLNLRQYFSKEAGDYLENLRQKLLP
                     KCPLLGKENDYGQKEVWPGLNELRGNISRGIKADWLSPNLIKGDLPLLEDPDQRLTVDN
                     GALGYGLLLARRGELAEKKEYLAWLKKQGAEKISAAGLFTGKAGLGGIVYELGDKAWGR
                     QLIWSAQGSSADLSLKSGLAGIALAKIALAKEEGLAKTAELIKIGREIAAGYQKMPTAG
                     LMTGQLGAILALWKLGKFLEEDSFKKEAKNGLDALLEKDLVQVDQHVFLAEDGRRMPYL
                     ANGTAGLALVLAAIAQDEPKEDRYQKIIIQAAETLDSFCSYMGGLFTGYAGLMLLDLAL
                     GRKKALGEKIRLLNNYLLPKEEGTLVAASCGYRCSMDLAAGASGVLLLLEGIARNDASL
                     WLPLVQTKNWRLF"
     CDS             complement(13822..15519)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 305.4; E-value:
                     1.3e-92)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_12"
                     /transl_table=11
                     /translation="MIKAGKIRMFSLDLRQILAILLSCLATALSLKIPLLLKQVIDHGK
                     MLSRTSSLGQIGFCLLISSLLEAVSQYLLSLAGDERIRDLRLLLQEKLLRLPWNYYKEN
                     SRGSLLSHVLNDSSVVKDFTVSVLPSALVSLLTVAASLEILLGLDVKMTLVIVLTFALI
                     ASSAFPLGKINEHFAYQNQAKLSRVSADLDENLANIKLIKLTNAQAGVLQKFRGDLQDL
                     FALSRKTDAVFSVTGPLQTVLTLAGFLLILLYGSQRLANGSLSLGMLSSFIMYMFGIIS
                     PINNLGNFYMSYAEARGSLKAISEILAQPDEADPGQELPKKAADLKVRDLTFAYPGSQS
                     PVLRDLSLDFKEGAKTALVGPSGAGKTTLINLLTRLEAGYQGQILLGDLEARNCSLPAW
                     RDLFSVVAQDNNIFAGTVADNLLFGLEKSVSRSDMIQALQVANLWPELDLDTQTGEGGW
                     KLSLGQSQRLQLARAYLRDAPCLILDEATANLDPESEAKVSQAVDRIAREKIVIIIAHR
                     LSTIANADKIYFLDQGQVQAAGRHEELLKHLPKYRAYVEDQLRPLESR"
     CDS             complement(15800..16969)
                     /locus_tag="ctg22_13"
                     /transl_table=11
                     /translation="MKRNKILASVSTVALALGALATFGGNHVDAATKSITPALPYRYKT
                     DTAYFLDKSTSAHYKGVWNSATNAWKKNGFAWKAAANHSKTTLSSYSDNSASGLNVAGY
                     DKVQYNKTTGKIISSEVRLNRAAFKKYGYNTAERTNVAEHELGHALGLDHNLKGSVSVM
                     NPANRYYSIQGCDVKGMKKIYSTVASFDSVSDNAGDIVTVVNYTPAVKSAVTAVKTSYN
                     AKTKSLTITGKAKGASKVAVSYNAKALKPVKVSKKGQFKTTVKFTGYKDFTLTGLNAKG
                     AAVTKAYVLAKDSYAAAKPTLLKADRTKKGLTFTTDAKKKTTLKFYYKNKLVKKTRLTK
                     DKQKVFFSAKSLKGKKGSFKVVASAAGKKSSQAAQFKIIGVGQATVTNY"
     CDS             complement(17148..17831)
                     /locus_tag="ctg22_14"
                     /transl_table=11
                     /translation="MKRNKILASVSTAALALGMLTVIGKKQVNAADNDDPANIVTVVNY
                     TPTKSAVTAVKTSYNAKTKSLTITSKAKGASKVAVSYNAKALKPVKATKKGQFKTTVKF
                     TGYKDFTLTGLNAKGAAVTKAYVLAKDSYAATKPTLLKADRTKKGLTFTTDAKKKTTLK
                     FYYKNKLVKKTKLTKDKQKVFFSAKSLKGKKGNFKVVASAAGKKSSQAAQFKIIGVGQA
                     TVTNY"
     CDS             complement(18510..19292)
                     /locus_tag="ctg22_15"
                     /transl_table=11
                     /translation="MSLLWSRLNKRWFVAAIAVGMAVGLGQIIVNCYTGMANIDSPYTR
                     WLSINTDSSATTIFFILLPFLASIPAGNMLKEDLDSGLFNKFKLQVPVARLIMQYAAMA
                     FMTGFVTIMIPLLLNLLGYLLILPNFKPDNLLNINIGVFNFNTMLVSLYYSHPFVHACL
                     NILLASVWGGLFSVFVLVNSVWIRNRFASLSTALVLELILMELDTVLPIDDMPSISPTD
                     FLPELGDRPLLWLTALMTIMLAAYCMGMYKLACRRAVL"
     CDS             complement(19305..19745)
                     /locus_tag="ctg22_16"
                     /transl_table=11
                     /translation="MSVIFRRYIMLHKKIVVVIASVLMTLGIVATAAPVFAGNTGNTYW
                     RSVYKVGSPYDHTPARKKENKSAYYNKTNNVHIKGGYIVIWAALYDGRDVSGGHSYRSY
                     QGQVTHLWNEAVERYGKGVAVRINSKKAAKGWADGVWSPDCK"
     CDS             complement(19742..20251)
                     /locus_tag="ctg22_17"
                     /transl_table=11
                     /translation="MKHKVWLAAAIVLFVLAGLRYWQVNANPVCRGVDKEIFVQRGQEV
                     HAPGIDFKILSAKMVKGKENVYLTVKVDLKDRDYYADGKHGIIAAVNNMYFNMPYSLSN
                     PSDLDVVDGKGHKVAIGYLTSKTPQPLTVKFDNVRSWYDTENAPARFSFLVGDGNGYKK
                     YSLLLE"
     CDS             complement(20241..20870)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 136.7; E-value:
                     1.7e-41)"
                     /gene_kind="transport"
                     /locus_tag="ctg22_18"
                     /transl_table=11
                     /translation="MFIELKNVNKVISGRQLLSQVNCEIEAGQIAVFEGINGSGKTLIL
                     KTILGLMKVDGEVLVAGKQVKPQDAYPVKAGILIENPSLITDFTATQNMELLAKLDEHI
                     SATEIAELLKYFDLSRFPNEKVKKFSLGMKQKLGIAEAFLGSYPLIVLDEPTNALDSDS
                     IDKLVDLIKLRQSKGCTFVIASHDRDFVEQVATKRFKVEEGVVHEA"
     CDS             complement(20881..21591)
                     /locus_tag="ctg22_19"
                     /transl_table=11
                     /translation="MRLFKDQFLYFWLLIKVRFLSWLLLTCLFLLVADGFMRNGRSANI
                     MVFQGLGLAEIRAGIRDFPVLWFGYFFFPLIISLNIFKELWISRVMHLRGQQIKPSHFS
                     WVNVILQLLLAAVYVLASNACLWLKDLLCGNSPLVLGPWQGGAAELHWMLIAWLGVSSL
                     LLIQASCSELTPALGLIMPIVLLVSTSLTAWSGNPLNALMLSRWTSGAELFMFVWTLIW
                     ALLYVLVDSKHGWV"
     CDS             complement(21593..22090)
                     /locus_tag="ctg22_20"
                     /transl_table=11
                     /translation="MLVPVQILLLLSTFRVRLQDIYVTGSRRIVWKQLEYHLAISLLVT
                     LVPWGAGCLIGMCLNGWGTRLGPIVAEALIRYLYLALSCLAILLLVSLCLLASKRIWAF
                     LAGFVLSGISYFLNVNHHFSLFYDFLIDDLGTLLLSRLPILLSIVLFLAVGVQMEIARK
                     DW"
     CDS             22194..22451
                     /locus_tag="ctg22_21"
                     /transl_table=11
                     /translation="MAARKYHLRIALSCSHCCLIIYIYTAPPLYFSSPLIAFSIVPHII
                     PVNIKFDKKIQAKVIDTCSSIMVSAALRLFLFSHIFILPF"
     CDS             complement(22440..22529)
                     /locus_tag="ctg22_22"
                     /transl_table=11
                     /translation="MSEQKAVIDEKILAERKLYFLMISPFLKR"
     CDS             complement(22526..23062)
                     /locus_tag="ctg22_23"
                     /transl_table=11
                     /translation="MNKKRATIISGLIVVLLLGTLLLLKHVDNSASAILEAKITADDDS
                     GTSFATIYDNGKLEKSRSSHNKQFVKPIEVDPQVFVEHTDKKNNIYLTVNEKALRKNKQ
                     VSSDENWVKLTKLIAKRSEHAIAMLNLFKLGDDYYAFLKYNAGLSDEGSLYQYKSSLTK
                     VATLDSGKISGLKKK"
ORIGIN
        1 gactttaaca gccaacatac ttagacgaga ttctcaattg aatggtgaag ctgccagttt
       61 tatttacgac atcatgtgtc caaaagacgc acggcattgg cttcatctcc actttatata
      121 gtaaaagaaa aagtgttgaa cgactactcc gtcgagtaat catccaacac cagattagta
      181 tgttttattg gccactaagc tatagtgttt ttagtaagtt ggtaaatggt gtgtatgtag
      241 taattggaac attttttcat gattccggat gtctactaaa aatggtggtg cttgtagcag
      301 gttgaatata tgaacaagtg tcgtaacgta tgagctatct gacatggttg cttgggcaag
      361 caaatattga ataaaagtta ataaatctac gtcactttca aagttatctg aaatcaaata
      421 tatataatcg atttttaatg gatcatgact atatctccat ccaggtacgg agtcaatatg
      481 gatgagatat gaatctagtc ctagtttagg gatatatatg gaccttaaac tttctggagc
      541 agccattcgg agcttattta attgtggttg gaaatagaaa tcattagtat ttctaaccgc
      601 aacggcttta ggaaatggca ttaggaacca atcactattt cgaacggcaa caatgtcatc
      661 actgataagc gaggccccct tatcaagcat tgatagaata aatgttgttt tgcctgatct
      721 actaggacca aatataacat gcgtttttcc atctaatata gtgcacatcc atgaatgaaa
      781 gtaaaagcat tgactaatgg tgctaaagag ataggcggaa gaatggttgt gttactcttc
      841 caagtcttta aatcatttct tgatttaccg tatgatacat ctattaaacc attttcgatg
      901 ttttctccaa ataataacgc attttctcca gtgctcgaat ggatatctat atagtatgta
      961 acctcactat cgcctacatt tgatacaatt tccggcttat atatataaga cagttgttca
     1021 atgatcggtt tgttattaga acttacggat aatgtgctat tccaaaacga aaaaaattgc
     1081 tggtaattca tcgcattaag gttccaatat atattttttt atcatagata aaacgtcatc
     1141 aatactgttt atgacatttg ttttgtcttc tgaagataga tcatatttac gctgaaaaac
     1201 attgtatagt tcatcagcgg ttatttgctt attatcagca taatattgat agatttctac
     1261 tccggttttg ttaaggatta ttggatcatg gttctctttg gtaaggattc cactatcaga
     1321 agtttgaata aaatctactt gtttcatatt ttttctccta aaaaaccgaa ctcaatgatt
     1381 gagttcggta tacttccgct tagcaccagg tcagttcgcc gcgatgacca ctacttgcgt
     1441 ataaagatga ctctaaggat aattccttta cttttgttga cttaaccttc aaaagggttg
     1501 ctttaggata tgtccagatt aacatagcgt acttcacctc ctttctagta gaatattttc
     1561 gatatttaaa gcaaacggaa atataagctt tgattggaca tcagagctac gggagctctc
     1621 atagaatgtg tcagtattta tgtattcatt tatttctatt tgtggagcaa gttgataaat
     1681 gggtaaaaag aaattggact tgccaactgt gacctttttg taagcccact tttttccata
     1741 tgtttcactg ccgattgata ccgtacttaa attagaccgt tggcattttt ctataaaaag
     1801 ttccgctgcg ctggcagtag tgttgttgaa tagtaacact actttttgat taatacagtg
     1861 ggcatttaac cactcgaagc atttagacat tgctgatatc tctccaccaa agttatatct
     1921 taggtctaat attaaggtcc ttctttttga aataacacca tatagctccg cgaattgtga
     1981 tacgttaaat gttagaattt gcatcattac aaagtggtta tttatcaaag gaggataaac
     2041 aatagatttt ggatctaatg gcatgagagg gatggtaaat atttcaccat tttcattttg
     2101 aatagtattg attcctatat gccaactccc cttttttatg gggctcatac cgtttacctt
     2161 cataattcta gtgactttat gtagcatttt tggaaaagag ttgatcagaa taagatcatc
     2221 atcctcccct atgcgtgtta ttaagccgaa tttagctaaa aaatcaggga ttttaccatc
     2281 gcctagaaca tatgagtatt tcttcatgac ttgatcagtg agttaaaatc tagctgcttg
     2341 tcaaagcgat tgaggttggt ttcgtcaatg gtgtgtgaca cgataatcat cgttcgattg
     2401 ccttgattga accagtcaaa gagcatatcc cagaaaacag cactggtatt tgcatcaagg
     2461 ttcgcggtag gttcatcaaa gataagggtt ctgctgtttg acagtaaccc tctaagcaga
     2521 aggactcttc tcttttcgcc tgttgagata cttgcagcat cagctgaatt taatgtgctc
     2581 tttttcaata gtttggcaca taatgctaat ttatcatctg aaggtgtgcg gtcaaaaaat
     2641 atattttcaa gaactgagcc attgaatagg gtgttctccg cttgcacaaa acggatgtcc
     2701 tgaaagacgt ttttatcggc ggcttgccca agtggagcgt tgtcgtatac aatgtctccg
     2761 ctatcgtaag gctgcaggcc agtcagcaaa tgtaggaaca aagttttccc gaccccgctt
     2821 ttaccacgga tgatgtagct atgaccgaag tcgaattgca tatctcggta tgagacttct
     2881 tggttggata attgaactgc cacattttcc aaagaaattt tcttggaaaa tgaaattgac
     2941 ttacggttag cactggcatt ctgaagcacg tattgatcga tatcagttct taccgccttg
     3001 gtgctgttta ttgaagaact gttgcgagat aaggaaagaa taggcatgct gagctgatcg
     3061 actagaccga gcagggtgat tactgaagac aatcctaatt tgccatggct gactagcagc
     3121 aaagagaaaa ctaaaactac aaaactggaa aaataggaga taaaggagta tgaagcatta
     3181 agcgtgtatt gcttaccttt tgagcttctt ttcaaattac gttcagtttc aagtgatgct
     3241 tgagcatttt tcagaacaaa agagcgaagg ttaaaaatgt gaactggaag aatgtttgaa
     3301 ataatgtctt cgtatttctt tagattcacc cctacttgat ccatatactt cttgttcagt
     3361 ttggaaatat tctctttgaa cacttgggtt acgcccagag gaatgaacat gagcgccaga
     3421 atgataatgg ctataatcca gttgattgag gctacagcta caaagacaaa aataaccctg
     3481 agagataggt aaagattatc aaaccacgcg ttatagtatg gatactccag gctgtcaata
     3541 gaattggtta agagctgagt agcctctttg tctgaactag cctgcttata tggcttgaat
     3601 ttagtaacag tacttaaaac agacttcttt aactcaaaga aggtctctga aaccagtttg
     3661 ttttcatact gccattctac gtagtagaag gaaacctcaa gcgtcattac cagcgcgaac
     3721 aataagaagc tgactaacaa ctgggagctt ttgctagata cggcttgctg gaacatttgc
     3781 ccttttagga attggatgta tgttgctgat cctacagaaa ccgacagtat cagcaataga
     3841 acgacaagct tagtattttt cacatgatag ataaactgct ttttcactaa tatatacact
     3901 ttcttgaaat tttcacgatc cgttcgttaa ttttttatta acttgtccca tcttcctcac
     3961 attatgctac aatttttatt gaagtcaacc ttttttatga aaaagactgc aaattactaa
     4021 attaaggaaa attacatttt ataacataat cattatgaga catcatgaca aaaattttaa
     4081 agcattacat gacaagaacg gcagttaatt caccatcaaa tcccgttagt cagaaggtat
     4141 ttaatgatat gttgtatgca gcatccgcgg atgtgtatca aatggctaag aaagaacagc
     4201 atacatcttt agaaagaaaa acgttagcta attattacgc tagatcaata tatagaacaa
     4261 cacctttcgg cttgttttcc gcagtagaat ttcataatag agattcagaa actaataaag
     4321 agtgtcatgc agtacaatat ttggttaaac ctattataaa gtcagaagca acatataaaa
     4381 tcacaacact tttgtccaaa acacacttca aggaactaaa actttttaag aatgataacg
     4441 ttttagagaa atctggcgat actttgctta atgtcttccc tatcgtggac aaacgaaaag
     4501 atgttatcga gaagtctatt gactataatt ttttaataca acaaatttta gagaaaatag
     4561 gggatgatgg aatcaccttt aactctttga ttaccgattt tcgtggcatc ttcccagaat
     4621 acttactgac caagataata agcatactga tagattctca ttttgtatta acagagcttg
     4681 aagatgagca ggcgtataca gatccgaatg tattgattaa caagatcgac tcgctagata
     4741 taaaggtgcc gctatttgtt aaagactact tttcatttaa agaaatgact ttagaggagt
     4801 tctcaacgaa ggctgcagaa gatgtaaatc agtggtttta tagtcagttt ggtaccaaaa
     4861 aagcagtatc ttatttatta gaagctgatg catcgcagag atatgactca gctgaatacg
     4921 acaacaaaat attgcggttt tgcaatttcc taaaaaagca ttctgcactt attccaagcg
     4981 cagaatttga atcagattat atgtggattg ttgatcacta tgggagtgca aaaataccat
     5041 taagcagctt aagagaaagg atatttgaag atgcttttct taatgagcat attagcaaaa
     5101 acgcgtctaa tgctattagt agaaaaatac gatctaatta tcagaaatat ataaatacta
     5161 ataacatccc actcaaagaa ctttttaagg atgttgaaaa taccgacaca gatagtttgg
     5221 tggatccaac attccaactg tgttttaaca tcagtcagag tggaacgctt caattatcac
     5281 caacgatagg tactcgtggc ataggatcaa ttgaaggaag attttctcga attaacccaa
     5341 aggaatttcg agaaataatt attcaaaaga acaaatatct taaagagctt ggcgtgacac
     5401 cagtaacagt aaagttgcta aacgttccgc gttttttctc tctgacatcg gatattgtcg
     5461 atggcagtga tttagaatta tcgatcaatt tgataggcac aggcagggac gtagtaaaac
     5521 tagatgaact ttacgttcaa gcaattaatg gacaaattct tatttttaga aagagaaagt
     5581 cagattttga gttgataaaa gttgaagcga ataatatggc gaattggcga aaaatatatc
     5641 cgcctattat acaaaagatg tttttgtgga gtgaaagata ttttagaaat gtcttgtttc
     5701 cgctagatat cataatcaaa gagcaaaagg aaaaggtaca taaccctgca gttttctttg
     5761 aagatatttt attgttgtgt gaaaactgga atccaattat tgaaattggc gaaggacttg
     5821 accgaaagtc attcacgtcc aatataaaaa actttattaa gaaatatagt attcctaaaa
     5881 aagtagcgct cgtttctggt gaccagcata tcttagtatc cctaaacgaa ctaggaataa
     5941 gtcaactatg gtcagaatac aagaaaatag gagcattcac actggagaac aatccaatgt
     6001 tcttagaaat atcctcaaag aacgaaagca ataacagtac caatttgacg gaatacattt
     6061 tgaatatagt taattctaca aataatggcc gcgaagaaaa ggcttattcc cagtatgtgt
     6121 ttacaaatga tgaaattgtt gcagaaaatt tggtatggac agaatatgat atctatcttc
     6181 ctaaaacgca tcaagatact tttatttgca gtgcgtttga catgataaga aatagcttat
     6241 ctataaggaa gacattcttc ataaaatatt ttgatcagcg atctcatatt agattacgtg
     6301 ttcaggcaac agagcgacaa aaagaaaaat tgtggttttg gcttttaaaa tgctatagaa
     6361 ataatgtgat atgtgatgtt gtgattaggc tgtatatccc agaaacatca cgttatgggg
     6421 caggaaatca actaaagaga attcatgagt tcttttgtca agatagctgt gagatagtag
     6481 aaaatgtact tgcagaagaa atgtctagag atgaaaagct tcaagtggca ttattgttgt
     6541 tactagatat aattacagct tcgtcaacaa cacaacttga tgaaattccg gtagtgaata
     6601 ataaacttct aaaaaagaat aagcatatat ggcgagaaga ttgggatcgc atcaaagcta
     6661 atatttcaga tagtccatta acagatagat ctgtggaaaa gaaaagtgcc cctcgtttta
     6721 gagcactcaa ggcttacttt aataacttta attctacaaa taatatagat aaactgtttg
     6781 caatacaaag tttgatccat atgactatca atagagtata tggaataaaa gcagaagaag
     6841 agggagaact aaactatttc ctcagtaaaa taatagctaa gtataggttt aagcaaaaat
     6901 aaacaatata gatacatttt tgccaagcta aaaagccccg acttcggtcg gggctttttt
     6961 tatacatttt cagctttatt ctttggcttc ctgcagtctg gccatcttat catagaccag
     7021 gccccgctgg ttttcatcga tttccaagac taaaaggtca ccggctaaca gcttggtatt
     7081 cccattaggg ataatatcct tttgcccccg gtggataact ctaaccaggg tgcggtccgg
     7141 ccaggcgatg tccttgacct ggtggtcagc caattggctg ccttcataaa tggaaacggt
     7201 cagctggtct gcttcaccga catagtcgtt gtcttctttg gtctgcatcc ggccagccag
     7261 gctttcatag atcggcaccc cgcccagcag ttcgttgacg acataagcgg caactgagac
     7321 cacggctaaa ggcatgaggt gcagcagtga cccaaccatt tccgcgatca gcatgatagc
     7381 ggtaaaaggc gagcggacga tggctgaaaa aagcccggcc atggagaaga tgatcaagtt
     7441 gacgaccaat ttttggtcca aaaggcccag gtcaaccatg aactggccat aaaccgcccc
     7501 caagagggcc cccatggtca agatcggcag gaagatcccg cccggcaggc cagaatcgta
     7561 agacacgata gaaaaactga tccgcaagag gaagatcaag accaggacat ttacggcgtg
     7621 aatttggttc aagctcaaga tcaagttgtt gcccccgccg acatagcctg ggaagtagta
     7681 catgatcggt actaagatga gggctgggat gatcccgtgc agccaacgcg gcaggacggg
     7741 gattttttga taaacatggc tgaaattgag caggccccac tggtagaagc gcccgatcaa
     7801 gcccaagaaa gcccccaata agagcagctg ccagtactgg aagatgggga agctatgctt
     7861 gtagtcgatc gctaagaccg gagtctggcc aaagacattg gaaaccacaa agttggccat
     7921 gatagctccg gccaaggcgt tcagccagac ccggggagaa aagttgtgaa agacttcttc
     7981 aacgatgaac atggccccgc ccaaaggtgc cccgaaggcc gcggacaagc cgctggccgc
     8041 cccggttgcc aggaggaccc gggagtcgct ctttgaagcc ttgaagccct gggccacccc
     8101 ctggccgact gttgaaccca attggattga cggaccttcc cggcctaaaa agaggccaga
     8161 cccgatcgac aggaccccgc cgacgaactt ccgccaaaag attggccacc aggccagttg
     8221 cagcttgccc tgcaactgaa gctctacttc aggaatcccg gacccgccgg catggggctg
     8281 ctgcttgact aagaagccgg ccacgatcac gctggccaga acgcccccgg ctaagagcca
     8341 caagagggct gggttagcgt gcgctgcctg gtagcctttt tgccacatgg ccagggtctg
     8401 cccgatcagc cagcggaagc tgccaacaac aatgcccgcc accaggccta cgaccagggc
     8461 ttcgaataat aagcgcaggt tggatttgcg cgtttgtctg tcttcactct ccatataatt
     8521 ttcgcctacc tttttttgca tataaaaaca gcataaacct tttaggcgga catgtaaaat
     8581 ctactttatc tcgtcaaggc ttcataagct cggccagccg gtaggcatgc tcctgcatga
     8641 gtgtcttcat ctgcttctgc cggccggctc cgtactcttc gacatcccca ttcacgaagg
     8701 agaccaggtg gcggcgcaga tcgatggctt cgatattgtc cgggttgacc aggcaggact
     8761 ggctgatttt ctccaagagg ggattttcct tggcgcactg gctgaggctg ccaaggaact
     8821 gggcttcacc ggcctgcttg acgattaaaa gcttgtgggg cgtcaaggtg gtcgtgatat
     8881 agaccaggtc ggttaatctg atgtttttga tctgccggcc cacccggtag gaaaaagcca
     8941 gctgcttggc tacagaatcc ttatgcagct gatccaaagc cacttccacg gtttccacaa
     9001 tccgccggcg ctgggccatg ggatccgcgc ctttgacgat gtagtcaacc ggccccagcc
     9061 ggcggcggta ggtgatgatc gacaggtcgg catggctggt cagaaaaatt atctgggccc
     9121 ggtcatcctg ctttttgatc agttctgcca ggtcaaagcc gttgtccgcg tccacttcct
     9181 ggtccaattc cacgtctaaa aagtagatgc cgccatctgc cgggtgactt aagagatatg
     9241 ccttggcgtc ttggtaattg ccttggctgg caaggtcaaa gcggattttt tcttcatctg
     9301 acaggatctg ttccgcccgc tttaaggtgt cggtgacctg gacgatctgg tctggatcgt
     9361 catcacaaat aaatacaggg tagctcatat ttcttcctcc acattttccg gcagcagggt
     9421 taggctgaag ttgaaccagc cgtcctctgg cccgtagtcc agcagcattt gttcatcatg
     9481 ctggctaacg atttctttga cattggccaa gccaaggcca gcgtgcgctt cttttgtcgt
     9541 gtagcccgcc tgggccaatt gatcagagtc gaccacgggc ccgccaatcc ggtttctgat
     9601 catgaattca aagtcaccgc cttcctggta gtacatggcc tccacccgtc cctggccgcc
     9661 cagggcttcc agctgctgac tggcttcaat ggcgttgtca aaagcaatgc cgataatccg
     9721 caccaggtcc aggagattag tttgagggat ctggctgatt tcgggctcgc agccgaaact
     9781 atagtcaatc ttttcattat agagcttggc cagcttggcg atggcgatgc tcttcagttc
     9841 gggaatcttg acgtggttga cgtcggggta tttgcgcagg gccttttggt caaactggct
     9901 gctggtgtat ttttccagct cttctaccag ggcatggctt cccccttttt ccgcactgac
     9961 cttgagactg agcaggatgt tctggtagtc gtgcttgaag cggcggagct cgtcttcgtt
    10021 tcggtccaga tagtccgcgt attccttcag ctgctcattt tccttgacca acaattgctt
    10081 ttgccgggcc agggcttcct gcttctgctg gtctaaaagc tgacgctgga tgtggacgat
    10141 ttcccggtag atcaccgcca gaaaaattgc ctggaagatc aaaaggaaga agaagaggag
    10201 gactacttcg gttggctttt tatcatcaag aatataggcg ccaatcgcgc agcagacaat
    10261 gtagagataa gccaggagac tgaccagaat gccgctgtta acatccgtca gcagggaagt
    10321 gatccgctgg cgctgccaga ttaacaaggc caaggcggcc agaggcagca gcaggttcat
    10381 gaaggcgtca aagtagaagt agcttggcaa aggcaggagg ctgaccagga ctttcatgct
    10441 gagctggatg accaggctga tgatgccaaa aagcaggcca gcccccagca gctggcggaa
    10501 gcggccagct tttttcagca aatagaagta tccgcaaaac agcagaatct ccagacctgt
    10561 ttcgtaaatc aggctgctgt aggtctgaaa attggataaa gccacggaca acacggcttc
    10621 aagggccagc aaaagcagcc agtcaagctt gccgggcttg atctgagcaa acaggcagaa
    10681 gagccagata tcaaccacgg cactgaaaat catcactaga atttgtaaaa acagggtcat
    10741 cggccgcctc ctttcaaagc tggcaagaac gacgaaaaga gcctggcttc tttgccaaac
    10801 tctttgcggg ggttaatgct tcttaccctt atggtgtttc ttgtgagaag agtgatttcc
    10861 atcaccaact ctactcccaa tacagattaa agagaagctc ttagagtctt caagacctgc
    10921 tccaccggca tttcctaatt gctgtaagtc caacacttgc atgtttacaa attcctcctg
    10981 tttttatttt ttctgcctgc aactgacagc tacaggcagg tggtcatcaa tcatttccga
    11041 tattttctcc aatgcagata aaggaatagt cctttccact tttgctggcg tagcccacgt
    11101 gcatcttgct gcggcgcgtg cttttttcta tatcatggcc aagattttcg caaaagtgct
    11161 ccagttctaa aataaagttc atcgtttacc tccatagtaa tgaccatcta cgacgctgcc
    11221 aatgcagata agggaaaagc ctttatgttt ctttttactt ttttctgcct tcgcctcatg
    11281 gccaagattt tcgcaaaagc gttccaagtc taaaataaag ttcatcgttt gcctcctaaa
    11341 aaagccgcca gttcttggtc tggacgaggg gcagccagag gctggcgtcg tttcgcgcga
    11401 ttccctccaa cagcagcaaa actccgcttg cccccgcggc cagatccatc gagcagcggt
    11461 agccgcaaga agcagccact aaagtcccct cttcctttgg cagtaaataa ttgttaagca
    11521 ggcggatttt ttctcccagc gccttcttcc ggcccaaggc caggtctagc agcattaagc
    11581 cggcatagcc ggtaaataag ccgcccatgt agctgcagaa gctgtccagc gtttccgctg
    11641 cttgaataat gattttctga tatctgtcct ctttcggctc gtcttgggca attgccgcca
    11701 agaccagggc caggccggcc gttccgtttg ccagataagg catccgccgg ccatcctctg
    11761 ccaaaaacac atgctgatcc acttgcacta aatctttttc caacaaggca tccagcccat
    11821 ttttggcttc ttttttaaaa ctgtcttctt ctaaaaactt tcccagcttc cataaggcaa
    11881 gaattgcccc caattggcca gtcatcaggc ccgcggttgg cattttctga tagccagccg
    11941 cgatttctct tcctatttta atcaactcag ctgttttcgc cagaccttct tccttagcca
    12001 gggcgatttt ggccaaggcg attcccgcga ggccagactt tagagacaaa tcagcactgc
    12061 ttccttgggc tgaccagatc aactgccggc cccaggcctt gtcccctaac tcataaacga
    12121 ttccgcccag gcctgccttt ccggtaaaca atccggcagc agatattttc tctgctccct
    12181 gctttttcag ccaggctaaa tattccttct tctctgccag ctccccccgt ctagccaaaa
    12241 gaaggccgta gcccaaggca ccgttgtcga ccgtcagccg ctggtccgga tcttctaaga
    12301 ggggcaggtc tcccttgatc aagttcggac tcagccagtc agcttttatt ccccgggaaa
    12361 tatttccccg cagctcgttc aaaccaggcc agacttcctt ttgcccataa tcattttctt
    12421 tccctaacag ggggcacttg ggcaagagct tctgccgcaa gttttccaaa tagtcccctg
    12481 cttcttttga aaaatactgg cgcaggttca agtcctgcat cggccagctt gctctagccc
    12541 ggttgctgat cggcaggaaa attgaccgga tgctttggta gagggcgtac aggtcagcct
    12601 gctcataatt ttcaagagcc aggtcactga aaccggcggt catgatccct ggatcatagg
    12661 gctgggccag ttccgcggcg gcttcaaagt cgatcagctt gacctcgcca tcttccgtaa
    12721 tcatgacatt gtcggcctgc agatcaccga tggctactcc ttgcgcatgc acgtgggcca
    12781 cggcctggcg cagcttttcc gctatctgca ggcttttagc cacgtaggct gcccgttttt
    12841 ccgggtagaa aggatagttt tcagctacat agtcccccaa agtctgcccg gaaacataat
    12901 cttcaaccaa ataggcgtga atccaagctt gaaagtcctc cttgccatct accacttccg
    12961 gcacatttgc caatttcttc aaccagcccg cttctttttg gatccggctg aaggcatcct
    13021 ggccatgacc atccagaccc gcggccggcc ggccttcctt gatcacgtaa tttttaccat
    13081 ttttctgggc caaatagaca ccgccgccat tactgaagtg gagggcctcc ttgatctggt
    13141 aagcagttaa tttgctgatc tctgctcctt taacttgaaa gttatctctt actagttcag
    13201 ctggctcttg cacaaagtcc ggctgataat aataaggaca gcgctggtcc tcctgccagc
    13261 tgccgtccgg cgcctgcagg cagcagcatt tttgcccgga aatttcttta actatttcct
    13321 tgaaggcgcc gtagcggtag taaaccggac tggcttgcca gcggcggtcg ctcaagatat
    13381 aagggccggg agcaaaatcc tttaacaaag ccgctaagtc aataactgtc tggacgaatt
    13441 ccccttcatc ttccgggtaa atggtgataa atttcccgct agctgcccgg tcggcatact
    13501 tggcattttt taacagccaa gcccgtcttg accgggtcac tttgaaggac gacagatgcg
    13561 caaaacagta atggctgacc aaatccagca tcccctgctc ctgccttaaa gctaccgaca
    13621 ggtgaatctt ccagccctgc tgggccaagg gccgggggct gaggcagcaa tgccagtctc
    13681 cctggtaaaa gttttgccaa tctgctggcg ggctgcaggt aaattcctgg tcactctttt
    13741 cagttgtatc cagctcataa taatcgctgt ctgcctgcag atagggctgg taatcttgtg
    13801 cttgataatc cattatttcc ttcacctgct ttccaaaggc cgcagctggt cttcgacata
    13861 ggcccggtac ttcggcagat gcttgagcaa ttcttcatgc cggccagccg cttgaacctg
    13921 accttgatct aaaaagtaga ttttatcggc attggcgatc gtcgacagac ggtgggcgat
    13981 gatgatgaca atcttttccc gggcaatccg gtcaacagct tggctgacct tggcttctga
    14041 ctcggggtcc aggttagccg tggcttcatc caggatcagg cacggggcat cccgcaagta
    14101 ggcccgggcc agctgcaggc gctggctttg tcccaaggac agcttccagc cgccctcccc
    14161 cgtttgggtg tccaggtcca gttccggcca aaggttggca acttgcaggg cctggatcat
    14221 gtccgaccgg ctgacggatt tttccaagcc aaagagcaaa ttgtcagcga ctgtaccggc
    14281 aaaaatattg ttgtcctggg caaccacgct gaagaggtcc cgccaggcag gcaagctgca
    14341 gtttctggct tccaggtcac ctagcaggat ctgcccttga tagccagctt ctaagcgggt
    14401 taaaaggttg atcaaggtcg tctttccagc tccggatgga ccaaccaaag ctgttttcgc
    14461 cccttcttta aagtccaggg acaagtcccg taaaaccggg ctctggctgc ctggataggc
    14521 aaaagtcagg tcgcggacct tgagatcagc ggcttttttc ggcagctctt ggccaggatc
    14581 agcttcatcc ggctgggcca ggatttcact gatggctttc agggagcccc gggcttcagc
    14641 gtagctcatg taaaagttgc ccaaattgtt gatcggagaa atgatgccga acatgtacat
    14701 gataaatgag ctcagcatcc ccaaagacag gctgccatta gccagacgct ggctaccgta
    14761 gagcaggatc aggagaaagc cggccagggt caagaccgtc tgcagagggc cagtcacgct
    14821 gaaaaccgcg tcagtcttcc gggacagggc aaacaagtcc tgcaagtccc cgcggaattt
    14881 ttgcaaaacg ccggcttggg cattggtcaa cttgatcagc ttgatattgg ccaggttttc
    14941 atccaaatct gcagataccc ggctgagctt ggcctggttt tggtaggcga agtgctcatt
    15001 gatttttcct aaaggaaagg cgctgctggc gatcaaggca aaagtcaaaa cgataaccaa
    15061 agtcattttg acatccagac cgagcaagat ctccaggctg gcggcaaccg ttaacaggct
    15121 gaccaaggct gagggcagga cgctaacggt aaagtccttg accactgaac tgtcgtttag
    15181 gacgtggctg agcagggagc cgcggctgtt ttccttatag tagttccaag gcaggcggag
    15241 gagtttttcc tgcaaaagca ggcgcaggtc tctgatccgc tcgtctccgg ccagactgag
    15301 caggtactgg ctgacggctt ccaagaggct ggaaatgagc aggcagaaac ctatctggcc
    15361 caggctgctt gtccgggaaa gcatttttcc atgatcgatc acttgcttta gcaagagagg
    15421 aattttcaag gacaaggcag tggccaggca gctcagcagg atcgccagaa tttgccgtag
    15481 gtcgagggaa aacatgcgga tttttccagc tttaatcatt gccgtggaaa caaatgaagc
    15541 tgtatctgtg ctgtcttctg cggtgccgct tggcgctttt gtcgtcgcgt tccaggattt
    15601 tttccatttc caaaataaag ttaaacattg tttttctcct catctaatca acttacaagg
    15661 caattgtagg ctatggagct ggccataaac gaaaaccgtc aaatttgccg cttttcgcgt
    15721 cattttcgtc agaaaaaggg caaaagaaaa agagcgaagc tcacggatgg agtctcgctc
    15781 tctagagtta tgttcgcttt tagtagttgg ttacagttgc ctggccaacg ccgatgatct
    15841 tgaattgggc agcttggctg ctcttcttgc cagcagctga ggcaacgacc ttgaagctcc
    15901 ccttcttgcc cttcagtgac ttggctgaga agaagacctt ttgcttgtcc ttggtcagcc
    15961 tagtcttctt gaccagcttg ttcttgtagt agaactttaa agtagtcttc ttcttggcgt
    16021 cggtcgtgaa ggtcagcccc ttcttggtcc ggtcagcctt gagcagggtt ggcttagccg
    16081 cagcgtagct gtccttggcc aaaacgtagg ccttggttac ggcagccccc ttggcgttta
    16141 agccagtaag agtaaagtcc ttgtagccgg tgaacttgac ggtcgtcttg aattggccct
    16201 tcttgcttac cttgactggc ttgagtgcct tggcattata gctgacagcc accttgcttg
    16261 cgcctttagc cttgccagtg atcgtcaatg acttggtctt ggcattgtag ctagtcttaa
    16321 cggcagtgac ggctgactta actgcaggcg tatagtttac aactgttact atatctccag
    16381 cattgtcgct aacgctgtca aatgaagcaa cagtggaata aatcttcttc attcccttaa
    16441 catcacaacc ttgaattgag tagtagcgat ttgctgggtt cataacagat acgctgccct
    16501 ttaaattgtg gtcaaggccc aaagcatgcc ccaattcatg ctcagcaaca ttcgttcgtt
    16561 ctgcagtgtt gtacccatac ttcttgaagg cagctctgtt caagcgaact tcactagaaa
    16621 tgatttttcc agtagtttta ttgtattgaa ccttgtcata gcccgcaaca ttgaggcctg
    16681 aagcgctatt gtcagagtag ctgctaaggg tcgtctttga gtgattagct gctgctttcc
    16741 aagcaaatcc atttttcttc caagcgtttg ttgctgaatt ccaaacgccc ttgtaatgag
    16801 ctgaagtaga cttgtctaag aaatatgccg tatctgtctt ataacgatat ggtaaggcag
    16861 gggtaattga cttagtagca gcatctacat gatttccacc aaaagttgcg agtgcaccta
    16921 aggctaacgc cactgttgaa acagaggcta aaatcttatt tcttttcatg tttccctcct
    16981 aaaaattaat taattaactt attctgtcat tgtagatcta ggaggagttc tctaacgaaa
    17041 aacgtcatat ttggcttatt tcgcatcata ttcgtcattt tcgtcaaaaa aaagaaaaag
    17101 agcgaagctc acggatggag tctcgctctc tagagttata ttcgctttta gtagttggtt
    17161 acagttgcct ggccaacgcc gatgatcttg aattgggcag cttggctgct cttcttgcca
    17221 gcagctgagg caacgacctt gaagttcccc ttcttgccct tcagtgactt ggctgagaag
    17281 aagacctttt gcttgtcctt ggtcagcttg gtcttcttga ccagcttgtt cttgtagtag
    17341 aacttcaaag tggtcttctt cttggcatcg gtcgtgaagg tcagcccctt cttggtccgg
    17401 tcagccttga gcaaggttgg cttagtggca gcgtaactgt ccttggccaa tacgtaggcc
    17461 ttggttacag cagccccctt ggcgtttaag ccagtaagag tgaagtcctt gtagccggtg
    17521 aacttaacgg tcgtcttgaa ttggcccttc ttagttgcct tgactggctt tagtgccttg
    17581 gcattgtagc tgacggcaac cttgcttgcg cctttagcct tgctagtgat cgtcaatgac
    17641 ttggtcttgg cgttgtagct agtcttaacg gcagtgacgg ctgatttagt cggagtatag
    17701 tttacaaccg ttacgatatt agcaggatca tcattgtccg cggcattaac ttgcttttta
    17761 ccaatgactg tcaacattcc taaggctaaa gccgccgttg aaactgaagc taaaatcttg
    17821 tttcttttca tattttcctc ctaaaaagca ttaatcaact tacgcgctca ttatgaaact
    17881 caagcagacg acgaatattt caaggcaact gatcaataca atggcttctt aaaggccagc
    17941 gaagttaaga aagcaaagct gccgaccatc atttccaaga aggcagccaa gacaagcgac
    18001 cagccggcca gcgcgagcca gctggcagcc ttgaagaagg aaatcaccaa ggctgaagcc
    18061 gtccagaaga aaacaatcta caagctgtca tcttcctacc gccgtgacta cctggactac
    18121 gcgctcagca acgcgcaaaa ggcactttcc ggcaataagg gtgaggtaac ttttgccaaa
    18181 tggctcctgg ccaactctga gacatatctt aatgggaaaa aggccccagt caccaacatc
    18241 aacaaactca gcaaggctga gtacgaacgc gtgcggagaa tcgtttcgga tgtagcgcca
    18301 aatggctaca tgacgaccat ttactacaag cgggcagatg gcacttggca cagaaaatac
    18361 agtgaacttt ggaacaacaa aaactgcaaa ttcgtttatg tcagcatgac gaccaaagag
    18421 aagaaattct tgaagatcag cgacttcgcg atgaaaagca gtcaactttt tgaaagctga
    18481 ctgcttttta ctcgctcatt ttttccaagt tacagcacgg cccggcggca agccagctta
    18541 tacatcccca tacagtaggc agctaacatt attgtcatca aagctgtcag ccacaacaaa
    18601 ggacggtccc ccagctctgg caagaaatca gtaggtgata tgcttggcat atcatcaatt
    18661 ggcaaaacag tatccaattc cattaaaatc agctctaaaa ccagggctgt actcaatgat
    18721 gcaaaacgat ttctgatcca aaccgagttg accaagacaa ataccgaaaa caaaccaccc
    18781 cagacggaag ctagcaatat attaagacat gcgtgaacaa aaggatgact ataatacaaa
    18841 gaaaccagca tggtgttgaa gttgaaaacc ccaatattga tattcaacaa attatctggc
    18901 ttaaaattag gaagaatcaa cagataccct agcaagttta aaagtagcgg aatcatgatg
    18961 gtcacaaatc cggtcataaa agccatagcc gcatattgca taatcaaacg agctacaggc
    19021 acctgcagtt taaacttatt gaatagacca ctgtctaagt cctcttttaa catgtttcct
    19081 gctggaatac tggctaagaa gggcaagagg ataaagaaaa ttgtcgttgc agatgagtca
    19141 gtgttaattg acagccagcg ggtgtaagga gagtcgatat ttgccatgcc agtgtagcag
    19201 ttgacgatta tctgacccaa gcccactgcc atgccaacag cgattgccgc aacaaaccag
    19261 cgcttattca gccttgacca caataaactc attttgttat caccttactt gcaatccgga
    19321 ctccaaacac catctgccca tcccttagca gctttctttg aattaattct cacagctacg
    19381 cctttcccat agcgttctac agcttcattc cacaaatgag tcacttgacc ttgataactc
    19441 ctataactgt ggccacctga aacatcacgt ccatcgtaaa gagctgccca aatcacgatg
    19501 tagccaccct taatatgtac gttgtttgtc ttattatagt aagctgattt gttttccttc
    19561 ttgcgagcag gagtatggtc gtaaggagaa ccaactttat aaacactacg ccaataagta
    19621 ttgcccgtat tccccgcgaa tacaggtgcg gccgtagcca caattcccaa cgtcatcaaa
    19681 actgatgcaa tcactacaac gatttttttg tgtaacataa tatatctcct aaaaattacg
    19741 ctcattccaa aagcagtgaa tacttcttat acccattgcc atccccaacc aaaaagctga
    19801 atctagccgg tgcgttttct gtatcgtacc aacttcgcac attgtcaaat ttcaccgtca
    19861 atggctgggg agtcttgcta gtcaaatatc caatggctac cttgtgacct ttgccatcca
    19921 ccacatcaag atctgatgga ttgctgaggc tgtatggcat attgaaatac atgttgttaa
    19981 ccgcggcgat tattccatgc ttgccatccg cgtaatagtc acgatccttc agatcaacct
    20041 ttacagtcaa atagacgttt tctttccctt tgaccatctt ggcggacaga atcttaaagt
    20101 cgattcctgg agcatgaacc tcctgccccc tttggacaaa aatttccttg tctaccccgc
    20161 ggcaaacagg attagcgttt acttgccaat agcgcaggcc tgccagtacg aacaagacga
    20221 tggctgctgc cagccatact ttatgcttca tgaaccacac cttcttcaac tttaaagcgc
    20281 ttggttgcca cttgctcaac aaaatcccgg tcatgtgagg cgatgacaaa agtgcatccc
    20341 ttgctttgcc gcaacttgat caaatccacc aacttatcaa tactatcgct atccaaagcg
    20401 ttggtcggtt catctaatac aatcagcgga tatgagccta agaaagcttc agcaataccc
    20461 agcttctgct tcatccctaa agaaaacttc ttgacctttt cattaggaaa gcggcttaag
    20521 tcaaagtatt tcagcaattc tgcaatttca gttgcagaaa tatgctcatc aagcttggct
    20581 aaaagctcca tattttgcgt tgccgtgaag tctgtaatca agctgggatt ttcaatcaaa
    20641 atccctgcct tgaccggata agcatcttgc ggcttgacct gcttgccagc taccaagact
    20701 tccccgtcaa ccttcatcaa gcccaaaatc gtctttaaaa tcaaagtctt cccagatccg
    20761 ttgatccctt caaaaaccgc gatctggcca gcctcaatct cgcagttgac ttgactgagc
    20821 agctgccggc ctgagatgac cttgtttaca ttctttaact caataaacat tcttcctcct
    20881 ttagacccag ccgtgcttgc tgtcaactaa tacgtacagc aaagcccaga tcagggtcca
    20941 cacaaacata aacaactctg cgccactggt ccagcggctc aacattaatg cattaagcgg
    21001 attgccgctc caagccgtca aagaggtcga aaccaacaag acgattggca taatcaagcc
    21061 caaagcggga gtgagctcac tgcaactggc ttgaatcagt aagagtgagc tgaccccaag
    21121 ccaggcaatt aacatccagt gcaattctgc tgctcctcct tgccagggtc ccagaacaag
    21181 aggcgagttg ccacacagca agtctttcaa ccacaggcag gcattgcttg ccaagacgta
    21241 aactgcggcc aagagcaact gcaatatgac attgacccag ctgaagtgac ttggcttgat
    21301 ctgctggccc cgcaggtgca ttaccctgct gatccacaat tccttgaaaa tattcaagct
    21361 gataatcagc gggaaaaaga aatagccgaa ccacaagacc ggaaaatctc taatgccagc
    21421 ccttatctct gccaatccaa gcccttggaa gaccattata ttggcacttc tgccgtttct
    21481 catgaaacca tcggcaacca gcaaaaacaa acaggtcaac agtagccatg ataggaacct
    21541 cacctttatc agcagccaga aatacagaaa ctgatcttta aaaagccgca ttttaccagt
    21601 cctttctagc gatttccatt tgcacgccaa cagctagaaa caagactatg cttagcagga
    21661 tcggcaagcg ggacagaagc agggttccca aatcatcgat aagaaaatca tagaacaagg
    21721 aaaaatgatg gttgacgttc aagaaatagg aaattccgct tagaacaaag ccggccagaa
    21781 aggcccagat tctcttgcta gccagcaaac agagactgac cagcaagaga atagccaggc
    21841 aggacaaagc caaatatagg tagcgaatca atgcttctgc cactataggc cctaatctgg
    21901 tcccccagcc attaagacac ataccgatta ggcagccggc tccccatggc acaagagtca
    21961 cgagcaaaga tatcgccaaa tggtactcca gctgtttcca aactattcgc ctgctcccag
    22021 taacatatat gtcttgcaga cggacacgaa atgtactcag taaaagcaag atctgaacag
    22081 gaaccagcaa gctgaaaaca agaaagcgtg agaatatggt ctggcttaac cactgatttt
    22141 gcggtgcgtc gcttaccaga atagcagtac tgcatccccc aaataaaatt aaaatggctg
    22201 ctaggaaata ccacttacgt atagcattgt cctgcagcca ttgttgccta ataatataca
    22261 tatatacagc tcctccctta tatttttctt cccctttaat cgctttcagt atagttccac
    22321 atataatccc tgtcaacata aaattcgaca aaaaaattca agcaaaagtc attgacacat
    22381 gctctagcat catggtaagc gcggctttaa ggctgttttt attcagtcat atatttatct
    22441 taccttttta aaaaaggaga aatcattaaa aaatataatt ttctttccgc cagtattttt
    22501 tcatcaatga ctgctttttg ctcgctcatt ttttctttaa acccgatatt tttccggaat
    22561 caagcgtggc cactttagtc aagctgctct tgtactgata aaggctgccc tcatctgaaa
    22621 gcccggcatt gtattttaga aaggcatagt agtcatcgcc aagcttaaac agattcagca
    22681 tcgcgatagc atgctcgctt ctcttggcaa tcagcttagt tagcttgacc cagttttcat
    22741 cagaagagac ctgtttgttt ttcctcaacg ctttctcgtt taccgttaaa taaatattgt
    22801 ttttcttgtc cgtatgctcc acaaaaactt gtgggtctac ttcaatcggc ttaacaaact
    22861 gcttgttatg gctggacctg cttttttcga gcttcccgtt gtcatagatg gtcgcgaagc
    22921 tagttccaga gtcatcgtct gccgttattt tggcttccaa aatcgcgctg gcgctgttgt
    22981 cgacatgctt tagcagcaac aatgtcccaa gcagcagaac gacaattaag ccagaaataa
    23041 tcgttgctct ctttttgttc atatgtttct accttaaatt tgtcctttat taaatttgtc
    23101 ctttataata atatacctta cctcctagag acgctgcgct caattctact tttctatata
    23161 ctgattacgc taaataagac agccttttca tcatatgtca caaatctttt ctggaaatct
    23221 cctactgaac aatgaaaagc ctaatattat catcaagcaa cagaagaatc aagcacgaca
    23281 aaacaaaaga gtgaaacttt ccaatgaagt ttcactcttt tcatcaatac tgtttgttat
    23341 ttttcttcat accattcggt gtggtaaacg ccctcgcggt cgtttctgta gtaagtgtgc
    23401 gcaccgaagt agtctctttg tgcctgaatc atgttggccg gcaggcttgg gttgaagatt
    23461 gattccaggt agttcagagc ggcgctgaag cttggagtcg gcacgccagc ttccgcagcc
    23521 agcttaacga ctgctcgcaa ggctggcagg ttcttttcca tcacgcccgc aaagtatggg
    23581 tcctggaaaa ggttgtccaa ttgctttccg tcagcgtagg catcttcaat gtggtacagg
    23641 gtcttggcgt ggatgatgca tcccgcttcc cagttctgcg cgatcgccgg gtagttcagt
    23701 tcccagtcgt aagccttagc ggccatagtc aactgctgga agccttgagc gtaagccacg
    23761 atctgtgcca ggtacattgc cttgcccaag ttgtcgatca agtcgctggc aac
//
