LOCUS gnlProkkaOMMEJOLA_1 24081 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|OMMEJOLA_1. ACCESSION gnlProkkaOMMEJOLA_1 VERSION gnlProkkaOMMEJOLA_1 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2025-04-28 22:35:35 Original ID :: gnl|Prokka|OMMEJOLA_1 NOTE: This is a single region extracted from a larger record! Orig. start :: 1027044 Orig. end :: 1051125 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..24081 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="True" /core_location="[20000:23819]" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" /tool="antismash" proto_core 20001..23819 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX))" /neighbourhood="20000" /product="NRPS" /protocluster_number="1" cand_cluster 1..24081 /SMILES="NC(C(C)CC)C(=O)O" /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(Condensation and (AMP-binding or A-OX))" /detection_rules="(HMGL-like and AMP-binding)" /kind="chemical_hybrid" /product="NRPS" /product="betalactone" /protoclusters="1" /protoclusters="2" /tool="antismash" region 1..24081 /candidate_cluster_numbers="1" /contig_edge="True" /product="NRPS" /product="betalactone" /region_number="3" /rules="cds(Condensation and (AMP-binding or A-OX))" /rules="(HMGL-like and AMP-binding)" /tool="antismash" CDS 396..1895 /locus_tag="ctg1_993" /transl_table=11 /translation="MKRSISIFITCLLITLLTMGGMLASPASAAGTKTPVAKNGQLSIK GTQLVNRDGKAVQLKGISSHGLQWYGEYVNKDSLKWLRDDWGITVFRAAMYTADGGYID NPSVKNKVKEAVEAAKELGIYVIIDWHILNDGNPNQNKEKAKEFFKEMSSLYGNTPNVI YEIANEPNGDVNWKRDIKPYAEEVISVIRKNDPDNIIIVGTGTWSQDVNDAADDQLKDA NVMYALHFYAGTHGQFLRDKANYALSKGAPIFVTEWGTSDASGNGGVFLDQSREWLKYL DSKTVSWVNWNLSDKQESSSALKPGASKTGGWQLSDLSASGTFVRENILGTKDSTKDIP ETPAKDKPTQENGISVQYRAGDGSMNSNQIRPQLQIKNNGNTTVDLKDVTARYWYKAKN KGQNFGCDYAQIGCGNVTHKFVTLHKPKQGADTYLELGFKNGTLAPGASTGNIQLRLHN DDWSNYAQSGDYSFFKSNTFKTTKKITLYDQGKLIWGTEPN" protocluster 1882..24081 /aStool="rule-based-clusters" /category="other" /contig_edge="True" /core_location="[11881:23819]" /cutoff="10000" /detection_rule="(HMGL-like and AMP-binding)" /neighbourhood="10000" /product="betalactone" /protocluster_number="2" /tool="antismash" proto_core 11882..23819 /aStool="rule-based-clusters" /tool="antismash" /cutoff="10000" /detection_rule="(HMGL-like and AMP-binding)" /neighbourhood="10000" /product="betalactone" /protocluster_number="2" CDS 1962..2225 /locus_tag="ctg1_994" /transl_table=11 /translation="MDEILKQYMVLYKKMSNMINGPDYPGKEKDIQHQKDQIEVYEKQL QQGFSTDYDYDVFADSVIKCAYGDMTLEDLEAVYYGLTTPFF" CDS complement(2485..3753) /locus_tag="ctg1_995" /transl_table=11 /translation="MIPRIKKTICVLLVCFTMLSVMLGPGATEVLAASDVTVNVSAEKQ VIRGFGGMNHPAWAGDLTAAQRETAFGNGQNQLGFSILRIHVDENRNNWYKEVETAKSA VKHGAIVFASPWNPPSDMVETFNRNGDTSAKRLKYDKYAAYAQHLNDFVTFMKNNGVNL YAISVQNEPDYAHEWTWWTPQEILRFMRENAGSINARVIAPESFQYLKNLSDPILNDPQ ALANMDILGTHLYGTQVSQFPYPLFKQKGAGKDLWMTEVYYPNSDNNSADRWPEALDVS QHIHNSMVEGDFQAYVWWYIRRSYGPMKEDGTISKRGYNMAHFSKFVRPGYVRIDATKN PNTNVYVSAYKGDNKVVIVAINKSNTGVNQNFVLQNGSASNVSRWITSSSSNLQPGTNL TVSGNHFWAHLPAQSVTTFVVNR" CDS complement(3884..5425) /locus_tag="ctg1_996" /transl_table=11 /translation="MRKKCSVCLFVFALLLSCLSGKSAYAATSSTIAKHVGNSNPLIDH HLGADPVALTYNGRVYIYMSSDDYEYNSNGTIKDNSFANLNKVFVISSADMVNWTDHGA IPVAGANGANGGRGIAKWAGASWAPSIAVKKINGKDKFFLYFANSGGGIGVLTADSPIG PWTDPIGKPLVTPSTPGMSGVVWLFDPAVFVDDDGTGYLYAGGGVPGGSNPTQGQWANP KTARVIKLGPDMTSVVGSASTIDAPFMFEDSGLHKYNGTYYYSYCINFGGTHPADKPPG EIGYMTSSNPMGPFTYRGHFLKNPGAFFGGGGNNHHAVFNFKNEWYVVYHAQTVSSALF GAGKGYRSPHINKLVHNPDGSIQEVAANYAGVTQLSNLNPYNRVEAETFAWNGRILTEK STAPGGPVNNQHVTSIQNGDWIAVGNADFGAGGARSFKANVASTLGGKIEVRLDSADGK LVGTLNVPSTGGAQTWREIETAVSGATGVHKVFFVFTGTGTGNLFHFDYWQFTQR" CDS 6555..7448 /gene_functions="biosynthetic-additional (rule-based-clusters) NTP_transf_3" /gene_functions="biosynthetic-additional (smcogs) SMCOG1064:glucose-1-phosphate adenylyl/thymidylyltransferase (Score: 231; E-value: 3e-70)" /gene_kind="biosynthetic-additional" /locus_tag="ctg1_997" /sec_met_domain="NTP_transf_3 (E-value: 2.8e-10, bitscore: 36.7, seeds: 297, tool: rule-based-clusters)" /transl_table=11 /translation="MRKKVRKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPAIQYIVEE AAESGIEDILIITGRNKRSIEDHFDRSVELEFNLREKGKTETLKEMQQIADLANIHYIR QKEPLGLGHAVLCAEHFIGDEPFAVLLGDDIMVSETPALRQLMDVYDVYGTEVVGVQSV LPEDVSKYGIINTSGSQGHVYEVNDLVEKPSPEEAPSEIAVMGRYVLNSSIFSVLKTIG RGAGNEIQLTDALREVCRKKPIHARLLEGNRYDIGDKLGCFKASTEIGLMHPEMRSQLL AYLEDVIKRETKEMLR" CDS 7512..8117 /gene_functions="other (smcogs) SMCOG1188:hypothetical protein (Score: 144.1; E-value: 4.8e-44)" /gene_kind="other" /locus_tag="ctg1_998" /transl_table=11 /translation="MKNVGSLISEILTWLTNMGYAGIAIGLMIEIIPSEIVLAYGGYMV SEGTIGFIGAIIAGVIGGTIAQIFIYWIGRYGGRPFLDKYGKYLLIKKHHIDMSENWFQ KYGAGVVFSARFIPVVRHAISIPAGIARMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQ WDDVENIAGTYTTPIMILAVVVIALYFVIKKRTAIFKR" CDS complement(8166..9365) /locus_tag="ctg1_999" /transl_table=11 /translation="MYHLYSHNDLDGVGCGIVAKLAFGKDVEVRYNSVNGLNAQVQYFL EKAKESNRQDALFITDLAVNEENEERLNEYVHAGGKVKLIDHHKTALHLNEHEWGFVQV EYDDGRLTSATSLLYGYLVENGFMKPTNALDQFTELVRQYDTWEWERYDQKQAKRLNDL FFLLSIDEFEAKMIQRLSAHDEFSFDDFEEKLLDLEDEKIERYLRRKKREMVQTFVHEH CVGIVHAESYHSELGNRLGKDNPHLDYIAILSMGSKRVSLRTIHDYIDVSEIAGRYGGG GHAKASGCSITDEVYELFVAEAFRIDPVRPDAFRNIYNLKGSANGSLYENRAQMRFFLF PLDNEWNIQINGETQDETFAAFEEAEWFIKRNYAASLVRDEVFVAFLAENLKLANQHRK " CDS complement(9533..11062) /gene_functions="biosynthetic-additional (smcogs) SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase, (Score: 544.8; E-value: 3.7e-165)" /gene_kind="biosynthetic-additional" /locus_tag="ctg1_1000" /transl_table=11 /translation="MDYEKERTERAERIRKGGAEKYHQSNREKGKLFVRERLSLLFDDD IELEDAFFAECMSDGLPADGVVTAIGKIGGQTVCVMANDSTVKAGSWGAKTVEKIIRIQ ETAEKLNCPLIYLVDSAGARITDQINVFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSA AGGAYIPAFCDIVVMVDGNASMYLGSPRMAEMVIGEKVSLEEMGGARMHCSISGCGDIL AETEEEAIQLARAYLSYFPANFQEKAPIHEKRPPKHFDTPLADVIPQNQNAPFDMHELI ERVIDEDSFFEIKALFAPELLTGLARIHGQPVGIVANQPKVKGGVLFHDSADKAAKFIT LCDAFHIPLLFLADIPGFMIGTKVEQAGIIRHGAKMISAMSEATVPKLSVIVRKAYGAG LYAMAGPAFEPDCCLALPTAQIAVMGPEAAVNAVYAKKIAELPEEERAAFISSKREEYK EDINIYRLASEMIIDAVIPANSLRDELAKRLKAYMTKEMTFTNRKHPVYPV" CDS complement(11079..11861) /NRPS_PKS="Domain: ECH (10-252). E-value: 2.3e-70. Score: 228.5. Matches aSDomain: nrpspksdomains_ctg1_1001_ECH.1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1023:enoyl-CoA hydratase (Score: 266.9; E-value: 2.3e-81)" /gene_kind="biosynthetic-additional" /locus_tag="ctg1_1001" /transl_table=11 /translation="MGDSILFTVKNEHIALVTLNRPQAANALSAEMLRNLQMIIQEIEF NSNIRCVILTGTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAI NGSALGGGLELALACDLRIATESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIY TGRRVTAHEAKEIGLVEHVTAPCDLMPKAKELAAAISANGPIAVRQAKFAINRGLETDL ATGLAIEQKAYEQTIPTKDRREGLQAFQEKRRAVYKGI" aSDomain complement(11106..11831) /aSDomain="ECH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1001_ECH.1" /evalue="2.30E-70" /label="ctg1_1001_ECH.1" /locus_tag="ctg1_1001" /protein_end="252" /protein_start="10" /score="228.5" /tool="antismash" /translation="NEHIALVTLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILT GTGEKAFCAGADLKERIKLKEDQVLESVSLIQRTAALLDALPQPVIAAINGSALGGGLE LALACDLRIATESAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEA KEIGLVEHVTAPCDLMPKAKELAAAISANGPIAVRQAKFAINRGLETDLATGLAIEQKA YEQTIPTKDRREGLQAFQEK" CDS complement(11882..12781) /gene_functions="biosynthetic (rule-based-clusters) betalactone: HMGL-like" /gene_functions="biosynthetic-additional (smcogs) SMCOG1271:2-isopropylmalate synthase (Score: 266.1; E-value: 1.1e-80)" /gene_kind="biosynthetic" /locus_tag="ctg1_1002" /sec_met_domain="HMGL-like (E-value: 2.4e-49, bitscore: 164.2, seeds: 15, tool: rule-based-clusters)" /transl_table=11 /translation="MSYPKKVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYI EITSFVHPKWIPALRDAIDVAKGIDRLKGVTYAALVPNQRGLENALEGGINEACVFMSA SETHNRKNINKSTSESLHILKQVNNDAQKANLTTRAYLSTVFGCPYEKDVPIEQVIRLS EALFEFGISELSLGDTIGAANPAQVETVLEALLARFPANQIALHFHDTRGTALANMVTA LQMGITVFDGSAGGLGGCPYAPGSSGNAATEDIVYMLEQMDIKTNVKLEKLLSAAKWIE EKMGKPLPSRNLQVFKSS" CDS complement(12796..13017) /locus_tag="ctg1_1003" /transl_table=11 /translation="MTVSIQMAGNLWKVHVKAGDQIEKGQEVAILESMKMEIPIVADRS GIVKEVKKNEGDFVNEGDVLLELSDSTQ" CDS complement(13032..14366) /gene_functions="biosynthetic-additional (rule-based-clusters) Dala_Dala_lig_C" /gene_functions="biosynthetic-additional (rule-based-clusters) ATP-grasp" /gene_functions="biosynthetic-additional (smcogs) SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score: 653.9; E-value: 5.2e-198)" /gene_kind="biosynthetic-additional" /locus_tag="ctg1_1004" /sec_met_domain="Dala_Dala_lig_C (E-value: 3.5e-16, bitscore: 55.2, seeds: 12, tool: rule-based-clusters)" /sec_met_domain="ATP-grasp (E-value: 2.9e-09, bitscore: 32.6, seeds: 20, tool: rule-based-clusters)" /transl_table=11 /translation="MFTKVLIANRGEIAMRIIRTCSRLGIKTVAVYSEADKDALHTKAA TEAYLIGESRVSESYLNIERIIKTAKKANADAIHPGYGLLSENSRFAERCKQENIVFIG PSPDIIAKMGSKIEARKAMEAAGVPVVPGVSESLGDIEAACRTASQIGYPVMLKASAGG GGIGMQRVENEEALKKAYEGNKKRAADFFGDGSMYIEKVIEHARHIEVQLLADQHGHTV HLFERDCSVQRRHQKVIEEAPSPFVDDELRMKIGQTAVKAAKAIGYTNAGTIEFIVDQK QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLRIAAGHTLTFSQKDIQRNGHAIEVRIY AEDPKTFFPSPGTITAFLLPDQKGVRHECAVAKDSTVTPFYDPMIAKMIVKGQTRTEAI EKLETALRDYRVEGIKTNLPLLIQAAATKAFKEGDVTTDFLKQHL" CDS complement(14376..16025) /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 8.8e-106. Score: 345.7. Matches aSDomain: nrpspksdomains_ctg1_1005_AMP-binding.1" /gene_functions="biosynthetic (rule-based-clusters) betalactone: AMP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 460.2; E-value: 1.1e-139)" /gene_kind="biosynthetic" /locus_tag="ctg1_1005" /sec_met_domain="AMP-binding (E-value: 3.4e-115, bitscore: 380.8, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MAELIHSTIGRLLEQTADAYPDRDAVVYPDRNIRYTYAQFDSLCR QTAKGLMRMGIGKGDHVAIWASNIPEWLVVQFATAKIGAVLVTVNTNYQAHELDYLLKQ SDAAALIIMDSYRGTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLSGMY HWDDIEILAKTVTDAELEERMNSLDKDDVINMQYTSGTTGFPKGVMLTHFNVINNAANI AECMALSSQDRMCIPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCT ALHGVPTMFIAELHHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQ TEASPVITQTRANDSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVM KGYYKDKDATRKAINHDGWLFTGDLAVMDEDGYCRITGRLKDMLIRGGENIYPREIEEF LYRHPAVLDVQVVGVPDAKFGEEAAAWIKLKDGKSVSPDDLKAYCKGKIARHKIPRYVI FTDDYPMTASGKIQKYKLREKTIEMFNLSSSQ" aSDomain complement(14691..15986) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1005_AMP-binding.1" /evalue="8.80E-106" /label="ctg1_1005_AMP-binding.1" /locus_tag="ctg1_1005" /protein_end="445" /protein_start="13" /score="345.7" /specificity="substrate consensus: X" /tool="antismash" /translation="EQTADAYPDRDAVVYPDRNIRYTYAQFDSLCRQTAKGLMRMGIGK GDHVAIWASNIPEWLVVQFATAKIGAVLVTVNTNYQAHELDYLLKQSDAAALIIMDSYR GTSYPDIVNSLIPELQEAKPGQLKSERYPFLKTLIYIGNKRLSGMYHWDDIEILAKTVT DAELEERMNSLDKDDVINMQYTSGTTGFPKGVMLTHFNVINNAANIAECMALSSQDRMC IPVPFFHCFGCVLGVLACVSVGAAMIPVQEFDPVTVLKTVEKEKCTALHGVPTMFIAEL HHPDFDAYDLSTLRTGIMAGSPCPSEVMKAVIERMGMKDITIAYGQTEASPVITQTRAN DSFIRRVETTGRALPHTEVKIVEPGTCQEVQRGMQGELCTRGYHVMKGYYKDKDATRKA INHDGWLFTGDLAVMDEDGYCRITGRLKDMLIR" CDS_motif complement(14793..14870) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1005_0002" /evalue="5.00E-04" /label="NRPS-A_a6" /locus_tag="ctg1_1005" /protein_end="411" /protein_start="385" /score="12.5" /tool="antismash" /translation="GMQGELCTRGYHVMKGYYKDKDATRK" CDS_motif complement(15390..15440) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1005_0001" /evalue="2.10E-07" /label="NRPS-A_a3" /locus_tag="ctg1_1005" /protein_end="212" /protein_start="195" /score="23.3" /tool="antismash" /translation="QYTSGTTGFPKGVMLTH" CDS complement(16069..17211) /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_N" /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_M" /gene_functions="biosynthetic-additional (rule-based-clusters) Acyl-CoA_dh_1" /gene_functions="biosynthetic-additional (smcogs) SMCOG1006:acyl-CoA dehydrogenase (Score: 458.5; E-value: 2.8e-139)" /gene_kind="biosynthetic-additional" /locus_tag="ctg1_1006" /sec_met_domain="Acyl-CoA_dh_N (E-value: 7.6e-39, bitscore: 128.8, seeds: 790, tool: rule-based-clusters)" /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.9e-27, bitscore: 91.3, seeds: 43, tool: rule-based-clusters)" /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.6e-55, bitscore: 181.0, seeds: 49, tool: rule-based-clusters)" /transl_table=11 /translation="MNFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFEKM GELGLMGIPFPEEYGGSGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTE EQKQTHLTPLASGTALGSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYA RTVIVTAVTDKNKDGKNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPA ANLLGDPTKGFKQFLYTLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPISSFQA IQFKLADMAMEIDLARQMVLKAAWLKDHNRPFTKEAAYAKLFASEMATRACNQAIQIHG GSGYMKEYGVERMLRDAKLMEIGEGTSEIQRLVIARQLLK" CDS complement(17833..19365) /locus_tag="ctg1_1007" /transl_table=11 /translation="MKVCQKSIVRFLVSLIIGTFVISVPFMANAQSDRELRAVWIASVL NIDWPSKKGLSVKEQKQEYSKLLDDVQKMGMNAVIVQIKPTADAFYPSAYGPWSEYLTG VQGKDPGYDPLAFMIEETHKRNLEFHAWFNPYRITMNHTDLNKLSESHPARKHPDWVAA YGNQLYYNPGIPEARDFIVKGIEEVVKHYDIDAVHMDDYFYPYKIAGQEFPDQAQYEQY GKDAFSNIDDWRRDNVNQLVKQINQTIKAAKPYVKFGISPFGVWRNAADDPTGSNTKAG VRNYDDLYADTRHWIQEGDIDYIAPQIYWSIGFNAAAYDVLADWWSNEVKNRPVHLYIG QAAYKINNNFDPPWSDPEEYVRQITLNRQLELVKGSMHFSLKDLNKNPLGIKDRLSTDL YSKPALVPQMPWLDNTAPKKPKLTKVTEDKNGNLLQIKDHPSNQKTKETAYYAIYRAEG KKQRTLLATQRKTHEQQTFLDNTADPNKKYTYYVTSADRLHNESKASKRTTK" CDS complement(19501..19893) /locus_tag="ctg1_1008" /transl_table=11 /translation="MDHLSFLTFIMLILASYRLTHLIVFDKITEFIRKPFMKKKRTVDQ NGHVDEKSVPASNFGYMLNCYWCAGVWCAILIGLGYLFLPRIAIPLIFILAIAGAQAIL ETAVGVGVKLIDVLKSLQTMMNDKKS" CDS complement(20001..23819) /NRPS_PKS="Domain: NRPS-COM_Nterm (0-29). E-value: 1.4e-15. Score: 48.1. Matches aSDomain: nrpspksdomains_ctg1_1009_NRPS-COM_Nterm.1" /NRPS_PKS="Domain: Condensation_DCL (8-309). E-value: 8.5e-119. Score: 387.9. Matches aSDomain: nrpspksdomains_ctg1_1009_Condensation_DCL.1" /NRPS_PKS="Domain: AMP-binding (474-867). E-value: 1.6e-109. Score: 358.1. Matches aSDomain: nrpspksdomains_ctg1_1009_AMP-binding.1" /NRPS_PKS="Domain: PCP (973-1040). E-value: 3.3e-23. Score: 73.6. Matches aSDomain: nrpspksdomains_ctg1_1009_PCP.1" /NRPS_PKS="Domain: Thioesterase (1060-1263). E-value: 9e-41. Score: 132.6. Matches aSDomain: nrpspksdomains_ctg1_1009_Thioesterase.1" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic (rule-based-clusters) betalactone: AMP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 341.1; E-value: 1.5e-103)" /gene_kind="biosynthetic" /locus_tag="ctg1_1009" /sec_met_domain="Condensation (E-value: 1.2e-88, bitscore: 293.0, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 1.4e-112, bitscore: 372.3, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 7.8e-16, bitscore: 54.3, seeds: 164, tool: rule-based-clusters)" /transl_table=11 /translation="MDNIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSL SYEWFQRSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLYSEDISHLPTNDQN EYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFM QIYQSIHAGRPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSTPSPLPRVSDKE TKEGYHREDLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAV VSGRPSEIPGVEQMIGLFINTIPIRIKTHQDETFQELLIRCQKEMLEAEPFTCQPLFDI QANTALKQELIDHIIVFENYPLQQKIADSADQTDSPLQIDQVQVSEQSGYNFNLVVAPG EELVVKFSYNAFVYDAAWISCIKRQFTQALSTAAQHPHMPIADFSFLDATEKEQIVTQF NNTKTEYPKNHTIIDLFREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFR KNETAGILAAHSPEFMISVLAVLKAGGAYLPLDEELPPERVSFMLEETQAKMLIVQKGL EQNAAFSGTCMIADAQALMGENHFPINTISSPDDLAYIMYTSGSTGRPKGVMITNRNVV SLVRNSNYTSASGDDRFILTGSISFDAVTFEMFGSLLHGASLHIIDKSTMLTPDRFGAY LLENDITVLFLTTALFNQLAQVRSDMFRGLHTLYVGGEALSPALMNAVRHACPDLALHN IYGPTENTTFSAFFELKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDG VAKGYLNKDDLTNAVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIRGKRI EPAEIEARLLEMEGVQEAAVTLREKDGEAQLYTHYVGDHKKTDTDFRADLARVLPDYMI PQHWVRVERMPLTGNGKIDRSALPIPENKPAKRQNIILPRNLVEEELANIWKQVLGVNT ISIDDDFFAIGGHSLKALQVIHTLKHQQNIDIPIDFLFEHPTIAQLAEKLYSKQLTAAD EQHVIKLNQHGAQNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYVNC MTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGNDE SAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIQIETSENTSLTKWEG ACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKITSNKAIPHKQ" aSDomain complement(20031..20639) /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1009_Thioesterase.1" /evalue="9.00E-41" /label="ctg1_1009_Thioesterase.1" /locus_tag="ctg1_1009" /protein_end="1263" /protein_start="1060" /score="132.6" /tool="antismash" /translation="QNLFCFPPISGFGIYFKDLALLLNEKAAVYGFHFIEQDTRIEQYV NCMTDIQPEGPYVLLGYSAGGNLAFEVAQAMERKGLEVSDFIIVDAYLKEQPLPIDTGN DESAAYLPEAVREKVMKKKRNYQEYWAQLLNEGHIKASIHFIEAGIQIETSENTSLTKW EGACGNYSEYTGFGAHKDMLEGTYAEKNADIILDILEKIT" aSModule complement(20031..23795) /complete /domains="nrpspksdomains_ctg1_1009_Condensation_DCL.1" /domains="nrpspksdomains_ctg1_1009_AMP-binding.1" /domains="nrpspksdomains_ctg1_1009_PCP.1" /domains="nrpspksdomains_ctg1_1009_Thioesterase.1" /final_module /locus_tags="ctg1_1009" /monomer_pairings="Ile -> Ile" /tool="antismash" /type="nrps" CDS_motif complement(20415..20486) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0010" /evalue="3.10E-13" /label="NRPS-te1" /locus_tag="ctg1_1009" /protein_end="1135" /protein_start="1111" /score="42.0" /tool="antismash" /translation="QPEGPYVLLGYSAGGNLAFEVAQA" aSDomain complement(20700..20900) /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1009_PCP.1" /evalue="3.30E-23" /label="ctg1_1009_PCP.1" /locus_tag="ctg1_1009" /protein_end="1040" /protein_start="973" /score="73.6" /tool="antismash" /translation="EEELANIWKQVLGVNTISIDDDFFAIGGHSLKALQVIHTLKHQQN IDIPIDFLFEHPTIAQLAEKLY" CDS_motif complement(21189..21254) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0009" /evalue="1.30E-09" /label="NRPS-A_a8" /locus_tag="ctg1_1009" /protein_end="877" /protein_start="855" /score="30.2" /tool="antismash" /translation="YISRIDRQMKIRGKRIEPAEIE" aSDomain complement(21219..22397) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1009_AMP-binding.1" /evalue="1.60E-109" /label="ctg1_1009_AMP-binding.1" /locus_tag="ctg1_1009" /protein_end="867" /protein_start="474" /score="358.1" /specificity="substrate consensus: Ile" /tool="antismash" /translation="FREQAEKTPDHTALVYGNMSISYKELDKRSNALARELIQKGFRKN ETAGILAAHSPEFMISVLAVLKAGGAYLPLDEELPPERVSFMLEETQAKMLIVQKGLEQ NAAFSGTCMIADAQALMGENHFPINTISSPDDLAYIMYTSGSTGRPKGVMITNRNVVSL VRNSNYTSASGDDRFILTGSISFDAVTFEMFGSLLHGASLHIIDKSTMLTPDRFGAYLL ENDITVLFLTTALFNQLAQVRSDMFRGLHTLYVGGEALSPALMNAVRHACPDLALHNIY GPTENTTFSAFFELKRDYAGPIPIGKPISNSTAYILDTKGRLLPIGVPGELCVGGDGVA KGYLNKDDLTNAVFSPHPFLPGERIYRTGDLARWLPDGNLEYISRIDRQMKIR" CDS_motif complement(21336..21425) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0008" /evalue="8.80E-15" /label="NRPS-A_a6" /locus_tag="ctg1_1009" /protein_end="828" /protein_start="798" /score="46.8" /tool="antismash" /translation="PIGVPGELCVGGDGVAKGYLNKDDLTNAVF" CDS_motif complement(21930..21986) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0007" /evalue="4.40E-10" /label="NRPS-A_a3" /locus_tag="ctg1_1009" /protein_end="630" /protein_start="611" /score="31.4" /tool="antismash" /translation="AYIMYTSGSTGRPKGVMIT" CDS_motif complement(22170..22211) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0006" /evalue="8.20E-06" /label="NRPS-A_a2" /locus_tag="ctg1_1009" /protein_end="550" /protein_start="536" /score="18.9" /tool="antismash" /translation="LAVLKAGGAYLPLD" CDS_motif complement(22737..22853) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0005" /evalue="1.40E-16" /label="C67_DCL_14fromHMM" /locus_tag="ctg1_1009" /protein_end="361" /protein_start="322" /score="52.9" /tool="antismash" /translation="QKEMLEAEPFTCQPLFDIQANTALKQELIDHIIVFENYP" aSDomain complement(22893..23795) /aSDomain="Condensation" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1009_Condensation_DCL.1" /domain_subtypes="Condensation_DCL" /evalue="8.50E-119" /label="ctg1_1009_Condensation_DCL.1" /locus_tag="ctg1_1009" /protein_end="309" /protein_start="8" /score="387.9" /tool="antismash" /translation="NIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSLSYEWFQRS IQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLYSEDISHLPTNDQNEYIERFKE KDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHA GRPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSTPSPLPRVSDKETKEGYHRE DLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEI PGVEQMIGLFINTIPIRIKT" CDS_motif complement(22902..22997) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0004" /evalue="1.30E-21" /label="C5_DCL_263-294" /locus_tag="ctg1_1009" /protein_end="306" /protein_start="274" /score="69.0" /tool="antismash" /translation="DVVFGAVVSGRPSEIPGVEQMIGLFINTIPIR" CDS_motif complement(23322..23387) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0003" /evalue="1.00E-12" /label="C3_DCL_135-156" /locus_tag="ctg1_1009" /protein_end="166" /protein_start="144" /score="40.4" /tool="antismash" /translation="HHHILMDGWCLGIVMQEFMQIY" CDS_motif complement(23613..23729) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0002" /evalue="9.80E-16" /label="C2_DCL_024-062" /locus_tag="ctg1_1009" /protein_end="69" /protein_start="30" /score="50.0" /tool="antismash" /translation="GAYVEQSLFTIKGSLSYEWFQRSIQAIIDRHDIFRTVFL" aSDomain complement(23733..23819) /aSDomain="NRPS-COM_Nterm" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_ctg1_1009_NRPS-COM_Nterm.1" /evalue="1.40E-15" /label="ctg1_1009_NRPS-COM_Nterm.1" /locus_tag="ctg1_1009" /protein_end="29" /protein_start="0" /score="48.1" /tool="antismash" /translation="MDNIKKIKNIYPLSHMQEGMLFHSFLRKE" CDS_motif complement(23748..23789) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_ctg1_1009_0001" /evalue="3.90E-05" /label="C1_DCL_004-017" /locus_tag="ctg1_1009" /protein_end="24" /protein_start="10" /score="15.5" /tool="antismash" /translation="YPLSHMQEGMLFHS" CDS complement(23848..24081) /locus_tag="ctg1_1010" /transl_table=11 /translation="MSAIAAEGKMTVNMTYDTTRFQRKTIEQLSETCRQFLLQLIEHCQ NKSETEKTISDYDDQELTEDALQEIADMLSFH" ORIGIN 1 cgtaagcaag gacttgatcc tgtgtttaaa gcgaaaaaca tcccagggct gaaaaacgct 61 gaaacatggg aagatgagaa acaagaagca taatataaat ataaaacaaa gctgcattca 121 atagttgaat gcagcttttt cattattgga aataaattta atttttcgac tcgaatgaaa 181 aatgacgtgt aaagtcccaa ttcagtccag ttttctttgt tctatatgtg tcatgtgtgt 241 cttattcaat ggagatagag taaattgaca ggcttttaaa cctcccaaaa acaagaaatt 301 aggttgatag acaatcatga gaaagatttt tacaatgagt tcgtgctcat aagaagtgga 361 gagccaaaat gatgcgaagg aggaaaagat cagatatgaa acggtcaatc tcgattttta 421 ttacgtgttt attgattacg ttattgacaa tgggcggcat gctggcttcg ccggcatcag 481 cagcagggac aaaaacgcca gtagccaaga atggccagct tagcataaaa ggtacacagc 541 tcgttaaccg agacggtaaa gcggtacagc tgaaggggat cagttcacac ggattgcaat 601 ggtatggaga atatgtcaat aaagacagct taaaatggct gagggacgat tggggtatca 661 ccgttttccg tgcagcgatg tatacggcag atggcggtta cattgacaac ccgtccgtga 721 aaaataaagt aaaagaagcg gttgaagcgg caaaagagct tgggatatat gtcatcattg 781 actggcatat cttaaatgac ggtaatccaa accaaaataa agagaaggca aaagaattct 841 tcaaggaaat gtcaagtctt tacggtaaca cgccaaacgt catttatgaa attgcaaacg 901 aaccaaacgg tgatgtgaac tggaagcgtg atattaaacc gtatgcggaa gaagtgattt 961 ccgttatccg caaaaatgat ccagacaaca tcatcattgt cggaaccggt acatggagcc 1021 aggatgtgaa tgatgcagcc gatgaccagc taaaagatgc aaacgttatg tacgcacttc 1081 atttttatgc cggcacacac ggccagtttt tacgggataa agcaaactat gcactcagca 1141 aaggagcgcc tatttttgtg acagaatggg ggacaagtga tgcttccgga aatggcggtg 1201 tattccttga tcaatcgcgg gaatggctga aatatctcga tagcaagacc gttagctggg 1261 tgaactggaa tctttctgat aagcaggaat catcctcagc tttaaagccg ggggcatcta 1321 aaacaggcgg ctggcagttg tcagatttat ctgcttcagg aacattcgtt agagaaaaca 1381 ttctcggcac caaagattcg acgaaggaca ttcctgaaac gccagcaaaa gataaaccca 1441 cacaggaaaa cggtatttct gtacaataca gagcagggga tgggagtatg aacagcaacc 1501 aaatccgtcc gcagcttcaa ataaaaaata acggcaatac cacggttgat ttaaaagatg 1561 tcactgcccg ttactggtat aaagcgaaaa acaaaggcca aaactttggc tgtgactacg 1621 cgcagattgg atgcggcaat gtgacacaca agtttgtgac gttgcataaa ccaaagcaag 1681 gtgcagatac ctatctggaa cttgggttta aaaacggaac gctggcaccg ggagcaagca 1741 cagggaatat tcagctccgt cttcacaatg atgactggag caattatgca caaagcggcg 1801 attattcctt tttcaaatca aatacgttta aaacaacgaa aaaaatcaca ttatatgatc 1861 aaggaaaact gatttgggga acagaaccaa attagttaag ctttttttgg cggacatcag 1921 taacgatgtc cgtttttatc atctaatagg aggtttgcgt tgtggatgaa atactgaaac 1981 agtatatggt gctgtacaaa aaaatgagta atatgataaa tggtccggac tatccaggta 2041 aggaaaaaga tatccagcat caaaaagatc agatcgaagt ttacgaaaaa cagctgcagc 2101 aaggattttc tacagattat gactatgatg tgtttgctga ttctgttatc aaatgcgcat 2161 atggcgatat gacgctggag gatttagaag ccgtttatta tggattgaca acgccatttt 2221 tttgatttgt cattcagcag aaaaatttta atttctgtct cactaactta agtatacttt 2281 tatattgaga cagaaattta tttattttct ttacttccta gaatatatat tatgtaaact 2341 agaaaagatg aagattaaag ctttgctgtt tttatgtaca tcctttcttc ttcctgtaat 2401 tcagcaacaa aataaaaaag cgatttccca atcggaaaaa tcgccaattc agacactcta 2461 ttatttttgt gtgtctttgt gctcttaacg atttacaaca aatgttgtta cgctttgagc 2521 tggaagatgg gcccaaaaat gattgcctga tacagtgaga ttcgttccag gttgtagatt 2581 gctgctgctg ctcgtgatcc atctagatac gtttgaagca gatccattct gcaaaacaaa 2641 gttttggttg acccctgtgt tgcttttgtt aatggcaaca ataacgacct tgttgtcacc 2701 tttataggct gacacgtaaa cgttcgtatt cggatttttc gttgcatcaa tccttacata 2761 gccgggacgc acaaacttcg agaaatgagc catattgtag ccgcgtttac tgatcgtacc 2821 atcttctttc ataggaccat atgatcttcg gatgtaccac catacataag cttgaaaatc 2881 tccctctacc atcgaattgt gaatatgctg tgaaacatcc aatgcctcag gccatcgatc 2941 cgccgagttg ttatcactgt ttggatagta tacttccgtc atccaaaggt ccttccccgc 3001 tcctttttgt ttgaaaagag gataagggaa ttggctgacc tgggtgccgt acaggtgagt 3061 tccgagaata tccatattgg caagagcctg cggatcgttc aagatcgggt ccgacaaatt 3121 ctttaagtat tgaaaagact caggtgcaat gacgcgggca ttgatcgagc cggcgttttc 3181 tctcataaag cgaagtattt cttgcggcgt ccaccacgtc cactcgtgag cgtaatcagg 3241 ctcgttttgg accgaaatcg cataaagatt cacaccatta tttttcatga aggtaacaaa 3301 atcgttaaga tgctgcgcgt atgcggcgta cttatcgtat ttcagccgct tagctgatgt 3361 gtcaccatta cgattaaagg tctcaaccat atcacttgga ggattccagg gagatgcaaa 3421 aacgattgcc ccatgtttga ccgcactctt ggcagtctcc acctctttat accaattatt 3481 tcggttttca tctacatgaa ttcttaagat tgaaaagcct aactgattct gtccattgcc 3541 aaaagcggtt tctctttgag ctgctgtaag atccccagcc caagccggat ggttcatccc 3601 tccaaaaccg cgaatcactt gtttctctgc agatacatta actgttacat cactggctgc 3661 caaaacttca gtagcgcctg gccctaacat gactgacagc atagtgaaac atactaatag 3721 tacacaaatt gtttttttta tgcgtggaat catttattcc tctccttcgt catgtgtctt 3781 ttacggtatt aaaaaatctg catggcatat ccataatggc gggctgttcc ggtgctgact 3841 cgtacttcac ccgcctcgtt tttaagcggt cccattacga gtcctatctt tgcgtaaact 3901 gccagtaatc aaaatgaaac aagtttcctg tacctgttcc ggtaaataca aagaatactt 3961 tgtgcacacc ggttgccccg cttactgcag tttctatttc tctccacgtt tgcgctccgc 4021 ctgttgaagg cacattcaga gttccaacaa gcttaccgtc tgcactgtcg aggcgcactt 4081 ctattttccc gcctaaagtg gatgctacat ttgctttaaa tgacctggca ccgcccgctc 4141 cgaagtctgc atttcctaca gcaatccagt ctccattttg aatgcttgtt acatgctgat 4201 tatttactgg cccgccgggt gctgtggact tctctgtcaa aatgcgtcca ttccaagcaa 4261 acgtttcagc ttctacccgg ttataaggat tcaaattaga aagctgtgtt acacctgcat 4321 aatttgctgc tacctcttgg atggatccat ctgggttatg caccagctta ttaatatggg 4381 gagaacggta tcctttgccg gccccgaaca gagcggaact gacagtttgc gcgtggtaca 4441 ccacatacca ctcgttttta aaattgaaaa cagcatgatg gttgtttccg ccacctccga 4501 aaaatgcacc cggatttttc aggaaatgcc ctctatatgt aaagggaccc atgggatttg 4561 aactggtcat gtagccgatc tcacccgggg gtttatcggc tgggtgcgtg ccgccgaaat 4621 taatgcaata ggagtaataa tatgttccgt tatacttgtg caatcccgaa tcttcaaaca 4681 tgaaaggcgc atcaattgta gatgcacttc caacaacact cgtcatatca ggccccaatt 4741 ttatgactct agccgtttta ggattggccc attgtccctg cgttggattt gaaccgccag 4801 gaacgcctcc cccggcatac aggtaaccgg tgccgtcatc atctacaaat actgccggat 4861 caaaaagcca tacaacacca gacattcctg gcgtacttgg cgttacgagc ggttttccga 4921 ttggatcggt ccatggacca atcgggctgt ctgcggtgag aaccccgata cctccgccgc 4981 tgtttgcgaa ataaaggaag aatttatcct tgccattgat tttttttact gcgattgacg 5041 gtgcccatga cgcccctgcc cattttgcta tcccacggcc accattagct ccattggcac 5101 ctgctactgg aatggctccg tggtctgtcc agttcaccat atccgctgaa gaaatgacga 5161 atactttatt caaattggca aatgaattat ctttaatcgt tccgttgcta ttatattcat 5221 agtcatcact tgacatataa atatagactc tcccgttata ggtcagcgca accggatccg 5281 ctcccaaatg atggtcgata agcggatttg aattccctac atgttttgca attgtactac 5341 tggtggcagc atacgcagac tttccagata aacagctcaa tagtaaagca aaaacaaata 5401 aacatacgct acactttttc ctcatcactt aacagcctcc tttttcctta aaatgaaggg 5461 ttcttttgaa atttgttaac aacaggtcat gaagactgca ccacttgttt cttcaagatc 5521 aatctagaaa agttccccca ttcctagcgg tcattgtcca gaaaataaaa tggcgaattg 5581 ttcaagtccc ctataacgct tgagcaggta tgtatattta ttcaaaaaaa tccctttatc 5641 taacatccta ccttattaaa aaaatagtgt atagaatact tttggaggaa ttcgtgttcg 5701 attctacaaa ggaactggat atatttattc attgtttaga tggggctaca tatacggctg 5761 ttaccgactc ttcttcgctt agactgttcc ctcgattatt gacataatag acatcatctc 5821 tgctgatagg gaatcaaggc ttaaaaccac tcaatctatt gaagtattgt tctcttcttt 5881 gcaagacctt tcgttatcat ttcgccctct tcccctgcga aatatgtcat attttttcat 5941 ctttatgtaa tgagcgtttt cgaaaaatca gccgttcatg ccgctgcttt ttaaagagta 6001 taaaaactaa tgagcggtat actcgctttt ttcatgtttt gttcatattt tattaattgt 6061 ttattcaaca ctgtccgcta tagtaatcca tatcaacaaa tatgactgcc actcgcatct 6121 tttatgaagg gaggtccgtt acgctgaaag aaaaaataaa gaccttaggc cgtttttgca 6181 ccgtaggcgt cggcaatacg ctgatagatt ttggtgtctt ctttcttctt accgcttgtc 6241 atgtctctta tctgccggcg cagatctgct cctatactgc aggtatcgtc aacagctatg 6301 tgtggaaccg gaattggacg ttttgtgtga aacgtaaggc tgacgggaaa gagatcgtgc 6361 gttttctcat gattaatatt gccgcgtcgg ggatcacctt tttgctgctt tatttgtttc 6421 aaaattgcgg ctgctcgctt ttggtgagta agctcgccgc cactatcggc ggaatgatga 6481 tgaattttat cggaaaccga atctgggtat ttggagattc gctgaaaaac atacaggatc 6541 aggagtgagg atgaatgaga aaaaaagtga gaaaagcggt tattcccgca gcgggtttag 6601 gaacgagatt tctgccggcg acaaaggcgc agcctaaaga aatgctccca atcgtcgaca 6661 aaccagcaat ccaatatatt gtagaagagg ccgcagagtc aggaattgaa gatatactga 6721 ttattacagg gagaaacaaa cgctcgattg aagatcattt tgatcggtcg gtcgaattgg 6781 aattcaatct ccgggaaaaa ggcaagacgg agacacttaa ggaaatgcag cagattgccg 6841 atttggccaa cattcattac atccgccaga aagaaccgct cggattaggc catgcggtgc 6901 tgtgtgcgga gcattttatc ggagatgagc cttttgctgt tctcttaggt gatgatatta 6961 tggtgtctga aacaccggct cttcggcaat taatggatgt atatgacgtt tatggcacag 7021 aggttgtcgg tgtacagtca gttctccctg aggatgtcag caaatatggt attataaata 7081 catcagggtc tcaagggcat gtatatgaag tgaacgattt agtggaaaag ccttctcctg 7141 aagaagcacc ttcggaaatc gcagtaatgg gacgttatgt gctgaattct tcgatcttct 7201 ccgttttgaa gacaattggc agaggcgcgg gcaacgaaat tcagctgaca gatgcgcttc 7261 gtgaggtttg ccgtaagaag ccgatccatg cccggctgct ggaaggaaat cgatatgaca 7321 ttggcgataa gctaggctgt tttaaagcga gcaccgaaat cggcttaatg catcccgaaa 7381 tgagatctca gcttttggcc tatttagaag atgtgatcaa acgggaaacg aaagaaatgc 7441 tgcggtaaaa aaattgtaac catcttgctc gtcaatcagt catataatag tgaaaaagat 7501 taggacaggt tgtgaagaat gtgggcagtt tgataagcga aattttaaca tggctgacga 7561 acatgggata tgcgggtatt gcgattgggt taatgattga aatcattccg agtgagattg 7621 tattagctta tggcggctat atggtatcgg aaggcacgat tggatttatt ggcgcaatta 7681 ttgcgggtgt tattgggggc accattgccc agatctttat ttactggatc ggtcgctatg 7741 gcggcaggcc atttctggac aaatacggga aatatttatt gattaaaaag catcatatcg 7801 atatgtcgga aaactggttt cagaaatacg gcgccggagt tgtcttctcg gctcgtttta 7861 taccggttgt cagacatgcc atatccattc cggcaggtat tgccagaatg ccttttctca 7921 aatttgtggt actgactgtg cttgctatca ttccatggtc tatcctgttt gtttatttag 7981 gcatacagct aggaagccag tgggatgatg ttgagaatat agcaggcact tatacaacac 8041 cgattatgat attggctgtt gtcgtgatag ccctttattt tgtgattaag aaacgtacag 8101 ccatatttaa aagatagcta gcggatatgc ataggggtga ctgacgctcc cctatgcata 8161 tttttttact tccgatgttg atttgccagc ttcagattct ccgctaaaaa tgcgacaaac 8221 acttcatccc gcacgagcga tgcggcataa tttctcttaa taaaccattc tgcctcttca 8281 aacgctgcga atgtttcgtc ttgggtttct ccgttaattt gaatattcca ttcgttgtct 8341 aaagggaaaa gaaaaaatct catttgtgcg cgattttcat ataatgatcc attcgcagat 8401 ccctttagat tatagatgtt acggaaggca tccggccgta caggatcaat gcggaaagct 8461 tcagctacaa acaactcgta tacttcatca gttattgaac agccggacgc ttttgcatgc 8521 cctccgccgc catatcggcc ggcgatttct gacacatcga tgtaatcatg aatggtgcgg 8581 agactgactc gttttgaccc catgctcaaa atcgcaatgt aatcgaggtg cgggttatct 8641 ttccctagcc tgttccccag ctctgaatgg tacgattcag cgtgaacgat gcctacacag 8701 tgttcgtgaa caaaggtttg taccatttcc cttttctttc tgcggaggta gcgctcgatt 8761 ttttcgtctt ctaaatcaag cagtttttct tcaaaatcat cgaaggaaaa ttcgtcatgc 8821 gcggaaaggc gctggatcat ttttgcttca aattcatcga ttgacagcaa aaagaaaaga 8881 tcattaagcc gcttcgcctg tttttgatcg taccgctccc actcccatgt atcgtattgg 8941 cggacgagct ctgtgaattg atctaaggcg tttgtcggtt tcatgaagcc attttcaacg 9001 agatagccat ataaaagcga tgtcgcggat gtgagccttc catcatcgta ttccacctgg 9061 acaaatcccc attcatgctc attcaaatga agggctgttt tatgatggtc aatgagcttc 9121 actttgcccc ctgcatgaac atactcattc aatctctctt cgttttcttc attgacggcg 9181 agatcggtga tgaataacgc gtcctgtctg ttgctctcct tcgctttttc taaaaagtac 9241 tgcacctgtg cgtttaagcc gttgacagag ttataccgga cctctacgtc ttttccgaac 9301 gctaattttg ctacgattcc gcaccctact ccgtccaagt cgttatgtga atataaatga 9361 tacataatgt gggccccttt ttatgataaa ctgacaattg ccgctagagg tgcggcagcc 9421 tttatttact attctaaaaa acaaagtgtt ttatgcaaat gtaattagtt gacataatgt 9481 tgttattgta aatatataaa agagcgcttt ttacgctcct aagttcttgc ttttatactg 9541 gataaaccgg atgctttcga ttggtaaatg tcatttcctt tgtcatgtat gccttgagcc 9601 gtttggccag ctcatcacgc agcgaattgg ctgggataac agcatcaatg atcatttctg 9661 aagccagacg gtagatattg atgtcctctt tatattcttc ccgtttgctg ctgataaatg 9721 cggctctctc ttcttctggc agctcggcga tttttttagc gtagacagcg tttacagcgg 9781 cctcagggcc catgacggcg atttgggcgg ttgggagcgc tagacagcaa tccggttcaa 9841 atgccggccc tgccattgca tacaaccccg ctccgtacgc ttttcggaca atgacagaga 9901 gctttggaac agttgcctcc gacatcgcag aaatcatttt cgctccgtgt ctgataatcc 9961 cagcctgttc tacttttgtg ccaatcataa aaccggggat atccgctaag aacagcaatg 10021 ggatatgaaa agcgtcacat aaggtaatga acttagccgc tttgtctgct gaatcgtgga 10081 ataagacgcc tccttttacc ttcggctggt ttgcaacaat gccgacaggc tgtccgtgga 10141 ttcgtgcgag gcccgtcaat aattccggtg caaataaggc tttgatctca aaaaatgagt 10201 cttcatctat gacccgctca atcagctcat gcatatcaaa aggtgcgttt tgattttgcg 10261 gaatgacgtc ggcaagcggg gtgtcgaagt gttttggcgg gcgtttctca tgaatgggcg 10321 ctttttcttg aaaatttgcc ggaaagtaag acaaataagc ccgcgccagc tgtatggctt 10381 cttcttcagt ttctgcaaga atatctccgc agccggagat tgagcaatgc atacgggcgc 10441 cacccatttc ttcaagagac actttttcgc caataaccat ttccgccatc cttggcgagc 10501 ctaaatacat ggaggcgtta ccgtctacca taacgacgat atcacagaag gccggaatat 10561 aagcgccacc tgctgcagat ggtccgaaaa gcagacagat ttgcggaatg cgtcccgata 10621 atttgacttg attgtaaaaa attcttcctg caccgcgtct ccctggaaag acattgattt 10681 ggtcggtaat tcgggcgcct gccgaatcga ctaaataaat gagcggacag tttaattttt 10741 cggcggtttc ttgaattctg atgatttttt caactgtttt agctccccat gaccccgctt 10801 tcactgttga atcattcgcc atgacgcaaa cagtttggcc gccgattttg ccgatagcgg 10861 tgacaactcc gtcagcggga agcccgtctg acatacattc cgcaaaaaaa gcgtcttcta 10921 gctcaatgtc atcgtcaaag agaagggaaa gccgctctct gacaaagagc ttgccttttt 10981 cccgattgct ttgatgatac ttttccgctc cgccttttcg aatccgttca gcccgttctg 11041 ttcgttcctt ttcataatcc atgagcattg cctccctttt atattccctt gtatacggcc 11101 cgtctttttt cttgaaaggc ctgaagccct tctctcctgt cttttgtcgg gatggtttgt 11161 tcatacgctt tttgttcaat cgcaaggcct gtagcgagat ctgtctccaa tcctctattg 11221 attgcaaatt tagcctgacg gacagcgatc ggcccgttgg cagaaatggc tgcggccagt 11281 tcctttgctt ttggcataag gtcacaagga gccgtgacat gctctacaag gccgatttct 11341 tttgcttcgt gtgcggtcac gcgtctgcct gtataaatga attcttttgc ttttcctctg 11401 ccaatcagcc ggggcagcct ttgggtccct ccagcgcccg ggataatagc taaccctgtt 11461 tccggaagtc ccagcacagc tgattcagtt gcgattcgaa ggtcgcatgc caatgccaat 11521 tctagtccgc cgcctaatgc gcttccattt atcgcagcta tgaccggctg aggcaaggca 11581 tcaagtaaag ccgccgttct ttgaatgaga gatacacttt ccagaacctg atcttctttc 11641 agttttatcc gttccttcag gtctgcccct gcacaaaacg ctttttcacc ggtgcctgtg 11701 aggatgacgc aacggatgtt tgagttgaat tcaatttcct ggataatcat ttgcaggttt 11761 ctaagcattt cagctgaaag agcatttgct gcctgaggcc tgtttaaggt gaccaacgca 11821 atatgttcat ttttaacagt aaaaagaata gaatctccca ttgtatgcgt cctccctttt 11881 atcaagatga tttaaacacc tgtaaatttc tgctcggcag cggtttgccc attttttctt 11941 caatccattt ggccgcagat agcagttttt ctagctttac atttgttttg atatccatct 12001 gttcaagcat gtacacgata tcctcagttg cggcgtttcc tgatgaacct ggcgcatatg 12061 ggcatccccc aagcccgcct gccgagccgt cgaacaccgt gatgcccatt tggagtgctg 12121 tgaccatgtt ggccagagcg gttcctctcg tatcatgaaa atgcaaggca atttgattag 12181 ccgggaatcg tgccaaaaga gcttcaagta cagtttccac ttgggcggga ttagccgctc 12241 caatcgtatc tccaagcgaa agttcagaaa tcccaaattc aaatagagct tctgaaaggc 12301 gaatgacttg ttcaatgggg acatcttttt cgtacggaca gccgaaaaca gtcgagaggt 12361 aggctcttgt tgtgaggttt gctttttgtg cgtcgttgtt tacttgtttg agtatatgaa 12421 gggattcaga agtggattta ttgatgtttt ttctgttgtg cgtctcgctg gcggacataa 12481 aaacgcaagc ctcgttaatg cctccttcaa gtgcattctc cagtcctctt tgattcggga 12541 caagtgccgc gtacgttacc ccttttaaac ggtcgatgcc ttttgctacg tcgatagcat 12601 ctcgaagcgc cggaatccat ttcgggtgaa cgaaggatgt gatttcaata tacgaaagcc 12661 ctgtccggga aagctggttg atccaggtta ttttatcctc tgttgcgatc catacgggct 12721 cgttttgtaa gccgtcacgc gggccgactt ctttgattgt cactttttta ggatatgaca 12781 tgttcttcct ccaaattatt gagtggaatc gctcagttcg agcagtacgt ctccttcatt 12841 tacaaagtcg ccttcatttt ttttgacttc ttttacgatt ccgcttctat ctgcaacgat 12901 cgggatttcc attttcatcg attccaaaat ggctacctcc tggccctttt cgatttggtc 12961 gccggctttg acgtggactt tccacaggtt tcctgccatt tgtatgctaa ccgtcatgac 13021 aactgcctcc tttataggtg ttgtttcaaa aagtcagtcg tgacatctcc ttctttaaat 13081 gcctttgttg ccgcagcctg tatgagaagc ggaagatttg ttttgattcc ctctacacga 13141 tagtcgcgaa gcgctgtctc tagtttttca attgcttctg ttctggtttg gcctttgaca 13201 atcatcttag cgatcatcgg gtcataaaaa ggggtaacgg tgctgtcttt tgctaccgca 13261 cattcgtgtc tgactccttt ttggtcagga agtaaaaacg cagtgatcgt acctggtgac 13321 gggaagaagg tcttgggatc ttccgcgtat attcgaacct ctatcgcatg cccgttccgt 13381 tggatgtctt tttgggagaa tgtgagtgta tggcccgcag caatccgcag ctgctgctca 13441 actaagtcca ggcctgttat ttcttcagtc acggggtgtt caacttgcag tctcgtattc 13501 atttcgagga aataaaaatt ttgcttctgg tcaactataa attcgatggt acctgcgttc 13561 gtatagccga ttgccttcgc tgcttttacc gctgtttgcc cgatcttcat tcttagttca 13621 tcgtctacaa atggagacgg tgcttcttca atgacttttt ggtggcgcct ctgaacagag 13681 caatcacgtt caaacagatg tactgtatgg ccgtgttgat cggccaaaag ctgaacctcg 13741 atgtgacgcg catgttcaat aactttttct atatacatcg acccgtcacc gaaaaaatct 13801 gctgcgcgct ttttgtttcc ctcgtacgct ttttttaatg cttcttcatt ttcaacacgc 13861 tgcattccga tgccccctcc gcccgctgaa gctttcagca tgacaggata gccgatttga 13921 cttgcggtgc ggcaggctgc ctctatatct ccgagggatt cagaaacgcc cggcaccaca 13981 gggacacctg cagcctccat tgcttttcgc gcttcaattt tgctgcccat ctttgcgatg 14041 atatcaggtg agggtccgat aaacacgatg ttttcttgct tgcagcgttc agcgaaccgg 14101 ctgttttctg ataacaatcc atatcccggg tggatcgcgt cggcatttgc ttttttcgcc 14161 gtctttatga ttctctctat atttaaataa ctttcactga ctctcgattc cccgatcaaa 14221 taagcctctg tagcggcttt tgtatggagc gcgtccttgt ctgcttctga ataaaccgcg 14281 accgttttaa tgccgagacg gctgcatgtt cggataattc tcattgcaat ttctccgcgg 14341 ttggcgatca gtacttttgt aaacatgatt tcacctcatt gacttgatga taggttgaac 14401 atttcaatcg ttttttctcg cagtttatat ttttgaattt tgcctgaggc cgtcatcgga 14461 tagtcatccg taaaaataac atagcgcgga attttgtggc gggcgatttt ccctttgcaa 14521 taggctttaa gatcatcagg tgaaacgctt ttaccgtctt tcagtttaat ccaggctgca 14581 gcttcctccc cgaatttggc gtcaggcaca ccaacgacct gtacatctaa aacagcggga 14641 tgccggtata aaaattcttc aatttcccgc ggataaatgt tctctccgcc tctgatgagc 14701 atatctttta atcttcctgt gatgcggcag tacccgtctt catccatgac agcaagatct 14761 ccggtaaaca gccatccgtc atgattgatt gcttttctgg tcgcatcttt gtctttataa 14821 tagcctttca tgacgtgata gccacgggtg cacagttctc cctgcatgcc tctttgaact 14881 tcttgacatg tcccaggttc tacaattttc acctcagtat gtggcagggc gcggccggtt 14941 gtttcgactc ttcttatgaa ggaatcattt gctctcgttt gtgtaatgac tggcgaggct 15001 tcggtttgtc cataggcgat cgtaatgtct ttcatgccca tcctttcaat cacagctttc 15061 atcacttcac ttggacaggg agagccggcc atgattcctg ttcggagcgt cgatagatca 15121 tatgcatcaa aatccggatg atgcagctcg gcgataaaca tggtaggcac accatggagc 15181 gctgtgcatt tctctttttc taccgtttta aggacggtaa cgggatcaaa ttcttgcacg 15241 ggtatcatgg ctgccccgac ggatacacat gccaaaaccc caagcacgca tccaaagcag 15301 tgaaaaaacg gaaccgggat gcacatgcgg tcttgagagg ataaagccat acattcagcg 15361 atattggcag cgttattgat gacattgaaa tgggtcagca tcacgccttt tggaaaccct 15421 gtcgttcctg atgtgtattg catattaatc acatcgtctt tatccaggct gttcattctt 15481 tcttccagct cagcatctgt cactgttttc gccaatatct ctatatcgtc ccaatgatac 15541 atgccagaca atcgtttatt gccaatatag atcagcgttt ttaaaaaggg atagcgttca 15601 gatttcagtt ggccgggctt tgcttcttgc agttctggaa ttaaactgtt cacgatgtct 15661 ggataagaag tgcccctgta tgaatccatg atgataagtg cggcggcatc cgattgcttt 15721 aacaagtaat caagctcgtg tgcttgataa ttggtattga cagttacgag cacggctccg 15781 atctttgcag ttgcgaactg gacgacaagc cattcaggga tattagaagc ccatatggcg 15841 acgtggtctc cttttccaat ccccatccgc ataagacctt tagcggtttg acggcacaga 15901 ctgtcaaatt gagcgtacgt atagcggata tttcggtctg gatacacaac agcatctcga 15961 tcgggatacg catcagctgt ttgttccagc agcctgccga ttgtggaatg gatgagttca 16021 gccattcatt gttcctcctt tcttaatgat aggaaagcgt ttacattttt attttaaaag 16081 ctgtctggcg atcacgagac gctgaatttc agatgtgcct tcaccgattt ccattaattt 16141 tgcgtcccgc agcatccgtt ccaccccata ctctttcata tagcctgaac ctccatggat 16201 ttgaatggct tgattgcaag ctcttgtcgc catttcagat gcgaatagct tggcgtacgc 16261 cgcttctttg gtgaacgggc ggttatggtc tttcagccag gcggctttta acaccatttg 16321 ccgtgccaga tcaatttcca tcgccatgtc agcaagctta aattgaatcg cttgaaagga 16381 agaaatcggc tgtccaaact gctttcgttc tttcgcatat gccaatgatg cgtcaagggc 16441 cgcttgggca atgccgactg caagagcagc gatggagatt cgccctccgt ccagcgtata 16501 tagaaactgt ttaaaccctt ttgttggatc gccaagtaag ttggccgcag gcactcttac 16561 atcctcaagc aaaatttccg ctgtattcga accgcggacg cccattttat cgtacgggct 16621 cgtaatcgta agtcctggtg tgtcagttgg cacgattaat gcggagatga tgttttttcc 16681 gtctttgttt ttgtctgtta cggcggttac aataactgtg cgtgcgtagc ttgcattagt 16741 gatccagcac ttttcgccgt tgattacata ctcgtcacca tttgaaatcg cttttgtttg 16801 agtgcctcct gcatctgagc cggcatttgg ctccgtcagg ccgaatgatc cgagtgctgt 16861 gcctgaagcc agcggcgtca aatgcgtctg tttttgctct tctgttccga agtagtaaag 16921 agggcttgcg cctagcgaga ccgctgcagc atagcttaat ccagtactgc cgcaggcttt 16981 gccgacttct tcaaccgcta aggcatatga aatcgtatca ccgccagatc cgccatattc 17041 ttctggaaat ggaataccca tcagaccgag ttcacccatt ttttcaaatg tttgcatcgg 17101 gaactcgcct gtttgatcta catgttcagc gtgaggagca atttcttttt tcgcaaaatc 17161 ttttaccatt tcacgcacca tttgttgttc ttttgtcagc tcaaaattca catcgtttcc 17221 tccttcacat ctttgtaaca tcctattagg cgagttctat aatcattccc tgacaagaaa 17281 agtctgaaaa ttaaaactga atcatttttt atgtgataat ttcagcggaa tgagcaaata 17341 catgcagtag gcgcatacca tccatatcgc aaacgcaata acttggccct ttgataaagc 17401 cgggaggatg aggggatgat tccaaaggga aatcgtatca atcaataaac cgaccgctga 17461 tccccatata cctagcttga tcactgcgaa ctgtgataga tcgagttttt gatagagaaa 17521 gaacacaaag cataaaacaa gagcggtgcc cgctctcaag agaagaaagt tcggcaaaaa 17581 ggcttcttca gccggatcag tcaacacagc atcttcgaac agcacaaaaa ataatgtggc 17641 acctaaccag actagaaatg aaaacgtaaa acacgtcctg tacgtgtttc tcttcgattt 17701 tacttagtac tagcttctca gattccaata atggaaaatg tccaaacacc gcctacagcg 17761 gtttaccatc atttcctgtc tccaaaatca cttttaaaaa aagacgactt agaaagccgt 17821 ccttctcatt tcttattttg ttgttcgttt ggaagccttg ctttcgttat gaagccggtc 17881 tgctgaagtg acataatacg tatatttctt gttaggatct gccgtgttat ctaagaaggt 17941 ttgctgctca tgtgtttttc tttgcgttgc cagcaatgtt ctctgctttt tcccttcggc 18001 tctgtatatc gcataatagg ctgtttcttt cgttttttga tttgatgggt gatctttaat 18061 ctgcagaaga ttgccgtttt tgtcttcggt gactttcgta agcttcggtt tttttggggc 18121 agtattgtca agccaaggca tttgcggaac cagtgccggc ttgctgtaaa gatcggtgct 18181 gagcctgtct ttgatgccaa gcggattttt gttgaggtcc ttgaggctga aatgcatgct 18241 tcctttcacc agttcaagct ggcggttcaa agtgatttgc cgcacatatt cctcagggtc 18301 ggaccaaggc ggatcaaaat tgttattgat tttatatgct gcctggccaa tatataagtg 18361 aacaggccta tttttgactt cattgctcca ccaatcagcc agcacgtcgt aagccgctgc 18421 gttaaagccg atactccaat aaatttgcgg agcaatataa tcgatgtcgc cttcttggat 18481 ccaatgtctt gtgtctgcat atagatcgtc ataatttctg acgcctgctt ttgtattcga 18541 tccggtcggg tcatctgcgg cgtttctcca tactccaaag ggactgatgc cgaatttgac 18601 atacggtttt gcagctttaa ttgtttggtt gatttgtttg acaagctggt tcacattgtc 18661 ccgccgccag tcatcgatat tagaaaaagc gtcttttccg tattgttcat actgtgcttg 18721 atcaggaaat tcctgtcctg ctattttata agggtaaaaa taatcatcca tatgaacagc 18781 atcgatatca taatgtttta cgacttcttc aatgcctttg acgataaaat ctctcgcttc 18841 tggaatgcct ggattataat acagctggtt tccgtaggcg gcaacccaat ctggatgttt 18901 tcttgccggg tgactctcag acaatttatt aagatctgta tgattcattg taatacggta 18961 agggttaaac cacgcgtgaa attccaaatt tcgtttatga gtttcttcaa tcataaatgc 19021 aagaggatca tagcccgggt ccttcccttg gacaccggtt aagtattccg accaaggccc 19081 gtaagctgac ggataaaagg catcagccgt cggtttaatc tgaacgataa cggcattcat 19141 tcccattttt tgcacatcgt ccagcagttt gctatactcc tgtttttgct ctttcacaga 19201 taaccctttt ttggacggcc aatcaatatt taatacggaa gcaatccata cggctctcag 19261 ctccctgtca gactgcgcat tggccataaa cggaacggaa atgacaaacg ttccgatgat 19321 caagctgaca aggaaacgga caatcgactt ttggcaaacc ttcattctgt ttcttctccc 19381 ccattacatc actttcacta ttcgctatta cggtattccc gggctataaa agggtgatta 19441 acagaatgtc tatctcacta aataaacgaa aaaagtccta aagcatgttg tgaaccgctt 19501 ttaggacttt ttatcattca tcatggtttg cagacttttt aacacgtcaa taagttttac 19561 gccgacaccg acagccgttt caaggatcgc ttgtgctccg gcaatagcta aaataaagat 19621 cagcggtatt gcaatacgag gcaaaaaaag atagccaagt ccgatcaaga tggcacacca 19681 aacaccggca caccagtagc aattgagcat gtatccaaag ttagaagccg gcacgctttt 19741 ttcatctaca tgcccgtttt gatcaacagt ccttttcttt ttcataaaag gttttcggat 19801 aaattctgtg attttgtcga atacaatcaa atgtgtcagc ctgtaactgg ctagaatcag 19861 catgataaac gtaagaaaag atagatgatc catgacaagc ctccaagaaa aaggatgatg 19921 ttatcattcc ctagtgtcat cgatccattc tttgatacaa aaagaagcgg acagagaatg 19981 cctctgtccg cgaatctgtt ctattgtttg tgcgggattg ctttatttga agtgatcttt 20041 tctaaaatgt caaggatgat gtcagcattc ttttcagcat atgttccttc cagcatgtct 20101 ttatgagcgc caaaacccgt gtactcgctg tagtttccac aggcgccttc ccatttcgtt 20161 aagcttgtat tctcgctggt ttcgatttga attccagctt cgatgaaatg aatgcttgct 20221 ttgatgtgcc cttcattcag caattgtgcc caatattctt gatagtttct ttttttcttc 20281 atcacctttt ctctgactgc ttcaggcaga tatgctgcag attcgtcatt cccggtatca 20341 ataggcaaag gctgttcttt tagataagcg tccacgataa tgaagtcgct gacttctaat 20401 cctttgcgct ccatagcctg tgccacttca aaagccaggt ttccgcctgc agagtagcct 20461 aataaaacgt atgggccctc aggctgtatg tccgtcatgc aattaacata ttgttcaatg 20521 cgggtgtctt gttcaataaa gtgaaacccg tatacggctg ccttctcatt cagcaataaa 20581 gcaaggtctt taaaataaat gccaaatccc gatatcggcg ggaagcagaa aagattttgc 20641 gcgccgtgct ggttcagttt gatcacatgc tgttcatctg ccgctgtcag ctgtttagaa 20701 taaagttttt cggcaagctg agcgattgtc ggatgttcga acaagaaatc aatcggtatg 20761 tcaatgttct gctgatgttt tagtgtatgt atgacttgca gtgcttttag tgaatgtccg 20821 ccaatagcaa agaagtcatc atcaatactg attgtgttaa caccgaggac ttgcttccaa 20881 atgttcgcca attcttcttc aaccaagttt cttggcaata tgatgttctg tcgtttggca 20941 ggcttatttt ctggaatagg cagcgcgctg cggtctattt ttccgtttcc ggtaagcggc 21001 atccgctcca cacgcaccca gtgctgcggg atcatatagt ctggaagcac acgcgccaaa 21061 tcggcgcgaa aatccgtatc tgtttttttg tgatcaccga cgtaatgagt gtacagctgc 21121 gcctctccat ctttttctct caatgtcact gctgcttctt gaacgccttc catttctaac 21181 agtcgcgctt ctatttcggc aggctcaatt cgttttccgc ggattttcat ttgcctgtca 21241 attctgctga tgtattctaa gtttccatca ggcagccagc gcgccaaatc accggtacgg 21301 tatattcttt ctccaggcaa gaaaggatga ggagaaaaca cagcatttgt caggtcatct 21361 ttgttcaaat agcctttagc gaccccatca ccgccaacac aaagctcgcc gggaacgcct 21421 attggcaaaa gacgtccttt tgtatctaag atgtaagcgg tgctattgct gattggtttt 21481 ccgatcggaa tcggccccgc atagtctctc tttaattcaa aaaaggctga aaaagtcgtg 21541 ttttccgtag gcccgtaaat attatgaagc gcgagatctg ggcaggcgtg cctgacagca 21601 ttcatcagag caggcgaaag tgcttctcct ccgacatata acgtatggag tccgcgaaac 21661 atatcagatc gtacctgtgc cagctgatta aaaagagctg tcgttaaaaa tagcactgtg 21721 atgtcatttt caagcaaata cgctccaaac cgatcaggtg tcagcattgt cgatttatca 21781 atgatatgaa ggcttgcgcc atgtaaaagt gacccgaaca tttcaaaggt gacggcgtca 21841 aagctgatag atccagtcag aataaaccgg tcatcaccgg acgcagacgt gtaattgctg 21901 tttctgacaa gggacacgac attgcgattc gtgatcatga cccctttcgg ccggcctgtt 21961 gatcctgagg tatacatgat atatgcaaga tcgtctggac tggagatggt gttgatagga 22021 aaatggttct ctcccatcaa tgcctgcgca tctgcaatca tacatgttcc tgagaacgca 22081 gcattttgct ccagcccctt ttgaacaatc agcatttttg cttgcgtttc ctcaagcata 22141 aagctgactc gttcaggcgg aagctcctca tcaagcggga ggtatgctcc ccctgctttt 22201 aatacggcaa gcacactgat catgaattcg ggagaatgtg cagccaatat tccggctgtc 22261 tcgtttttcc gaaatccctt ttgaattaac tctctggcga gcgcattaga gcgtttatca 22321 agctctttat atgaaataga catattgcca tacacaagtg cggtatggtc tggcgtcttt 22381 tctgcttgtt cgcgaaataa atcgataatt gtatgattct ttggatactc cgtttttgta 22441 ttgttgaact gtgtgacaat ctgctctttt tctgttgcat caagaaaaga aaaatcagca 22501 attggcatat gagggtgctg tgcagctgtg ctaagcgctt gtgtaaattg cctcttgata 22561 cagctgatcc aggcagcatc gtaaacgaat gcattatagc tgaacttgac gacaagctct 22621 tcgccgggag caacgacaag attaaagtta tatcctgatt gctcggatac ttgaacttga 22681 tcgatttgca gcggtgaatc ggtttgatca gcggaatcgg cgattttctg ctgtaacgga 22741 tagttttcaa agacgataat gtgatcaatc agttcctgtt ttaatgcggt gtttgcctga 22801 atatcaaata aaggctggca ggtaaacggc tcagcttcca gcatttcttt ctggcatcgt 22861 atgagcagtt cttgaaacgt ttcgtcttga tgtgttttaa ttcgaatcgg tatggtattg 22921 ataaacaacc ctatcatttg ctccacgccc gggatttctg acggtcttcc tgatacaact 22981 gcgccaaaca caacgtcgtc tgtgcggtta tattgctgca gcatcacacc ccagaccgcc 23041 tgaattaggg tagcgagcgt gacgccgtgt tgtttggcag tctctttcag cttgtctgtc 23101 agtggtttat ttaatgaaaa tatcaaatct tcacggtgat aaccttcttt tgtttcttta 23161 tcagacacac gaggcagagg tgatggagtg ctgtagtttt ttaaataggt atcccagtag 23221 gctgctgctt tttctttgtc tcggtttgtc agccaggaaa tataggtgct gtacggacgg 23281 acagggtcta atgaaagcgg ccttcctgca tgaatcgatt gataaatttg cataaattcc 23341 tgcataacaa tacctaggca ccatccgtcc attaaaatat gatggtgact ccagatacag 23401 acatgttcat ctttagctgt tttgaataga gaaatccgca tcagcatgtc tttttgcaga 23461 tcaaagcctt tttgcttgtc cttctcttta aagcgttcaa tatactcatt ctgatcgttt 23521 gttggcagat gggaaatgtc ttcgctgtac aaatggaatt cacgttctgt catcacgact 23581 tgccgaggtc ccgacaaatg cgggacgtgc ggcaaaaaca cggttctgaa aatatcatgg 23641 cggtcgataa tggcttgaat gctgcgctga aaccattcat agctgaggct tcctttaatg 23701 gtgaagagcg actgctcaac gtatgccccc tcctctttac ggaggaagga atgaaacagc 23761 attccctcct gcatatgact cagaggataa atgttcttga tttttttgat gttatccata 23821 gtgtctgcac ctttcttcac ggtttcatta gtgaaaactg agcatatcag caatctcttg 23881 cagggcgtcc tcggtcagtt cttgatcatc ataatcgctg atcgtttttt ctgtttcgct 23941 tttgttctgg cagtgttcga tcagctgtaa taaaaattga cggcatgttt cgctaagctg 24001 ttcgatggtt ttgcgctgaa aacgggtagt gtcataagtc atattgacag tcattttccc 24061 ttctgcagcg attgcactga t //