Select genomic region:
Overview
1.1
6.1
8.1
13.1
16.1
28.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaIMNAJMDP_1 (original name was: gnl|Prokka|IMNAJMDP_1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NI-siderophore | 1 | 18,312 |

gnlProkkaIMNAJMDP_6 (original name was: gnl|Prokka|IMNAJMDP_6)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 6.1 | RiPP-like | 1 | 5,498 |

gnlProkkaIMNAJMDP_8 (original name was: gnl|Prokka|IMNAJMDP_8)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 8.1 | T3PKS | 139,154 | 168,226 |

gnlProkkaIMNAJMDP_13 (original name was: gnl|Prokka|IMNAJMDP_13)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 13.1 | HR-T2PKS,hglE-KS | 60,429 | 106,993 | cinnapeptin | NRP | 7%

gnlProkkaIMNAJMDP_16 (original name was: gnl|Prokka|IMNAJMDP_16)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 16.1 | ectoine,lanthipeptide-class-iii | 53,827 | 77,590 | ectoine | Other | 75%

gnlProkkaIMNAJMDP_28 (original name was: gnl|Prokka|IMNAJMDP_28)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 28.1 | cyclic-lactone-autoinducer | 1 | 19,749 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | NI-siderophore | 1 | 18,312 |
Region 6.1 | RiPP-like | 1 | 5,498 |
Region 8.1 | T3PKS | 139,154 | 168,226 |
Region 13.1 | HR-T2PKS,hglE-KS | 60,429 | 106,993 | cinnapeptin | NRP | 7%
Region 16.1 | ectoine,lanthipeptide-class-iii | 53,827 | 77,590 | ectoine | Other | 75%
Region 28.1 | cyclic-lactone-autoinducer | 1 | 19,749 |

No secondary metabolite regions were found in these records:
  gnlProkkaIMNAJMDP_2 (original name was: gnl|Prokka|IMNAJMDP_2)
  gnlProkkaIMNAJMDP_3 (original name was: gnl|Prokka|IMNAJMDP_3)
  gnlProkkaIMNAJMDP_4 (original name was: gnl|Prokka|IMNAJMDP_4)
  gnlProkkaIMNAJMDP_5 (original name was: gnl|Prokka|IMNAJMDP_5)
  gnlProkkaIMNAJMDP_7 (original name was: gnl|Prokka|IMNAJMDP_7)
  gnlProkkaIMNAJMDP_9 (original name was: gnl|Prokka|IMNAJMDP_9)
  gnlProkkaIMNAJMDP_10 (original name was: gnl|Prokka|IMNAJMDP_10)
  gnlProkkaIMNAJMDP_11 (original name was: gnl|Prokka|IMNAJMDP_11)
  gnlProkkaIMNAJMDP_12 (original name was: gnl|Prokka|IMNAJMDP_12)
  gnlProkkaIMNAJMDP_14 (original name was: gnl|Prokka|IMNAJMDP_14)
  gnlProkkaIMNAJMDP_15 (original name was: gnl|Prokka|IMNAJMDP_15)
  gnlProkkaIMNAJMDP_17 (original name was: gnl|Prokka|IMNAJMDP_17)
  gnlProkkaIMNAJMDP_18 (original name was: gnl|Prokka|IMNAJMDP_18)
  gnlProkkaIMNAJMDP_19 (original name was: gnl|Prokka|IMNAJMDP_19)
  gnlProkkaIMNAJMDP_20 (original name was: gnl|Prokka|IMNAJMDP_20)
  gnlProkkaIMNAJMDP_21 (original name was: gnl|Prokka|IMNAJMDP_21)
  gnlProkkaIMNAJMDP_22 (original name was: gnl|Prokka|IMNAJMDP_22)
  gnlProkkaIMNAJMDP_23 (original name was: gnl|Prokka|IMNAJMDP_23)
  gnlProkkaIMNAJMDP_24 (original name was: gnl|Prokka|IMNAJMDP_24)
  gnlProkkaIMNAJMDP_25 (original name was: gnl|Prokka|IMNAJMDP_25)
  gnlProkkaIMNAJMDP_26 (original name was: gnl|Prokka|IMNAJMDP_26)
  gnlProkkaIMNAJMDP_27 (original name was: gnl|Prokka|IMNAJMDP_27)
  gnlProkkaIMNAJMDP_29 (original name was: gnl|Prokka|IMNAJMDP_29)
  gnlProkkaIMNAJMDP_30 (original name was: gnl|Prokka|IMNAJMDP_30)
  gnlProkkaIMNAJMDP_31 (original name was: gnl|Prokka|IMNAJMDP_31)
  gnlProkkaIMNAJMDP_32 (original name was: gnl|Prokka|IMNAJMDP_32)
  gnlProkkaIMNAJMDP_33 (original name was: gnl|Prokka|IMNAJMDP_33)
  gnlProkkaIMNAJMDP_34 (original name was: gnl|Prokka|IMNAJMDP_34)
  gnlProkkaIMNAJMDP_35 (original name was: gnl|Prokka|IMNAJMDP_35)
  gnlProkkaIMNAJMDP_36 (original name was: gnl|Prokka|IMNAJMDP_36)
  gnlProkkaIMNAJMDP_37 (original name was: gnl|Prokka|IMNAJMDP_37)
  gnlProkkaIMNAJMDP_38 (original name was: gnl|Prokka|IMNAJMDP_38)
  gnlProkkaIMNAJMDP_39 (original name was: gnl|Prokka|IMNAJMDP_39)
  gnlProkkaIMNAJMDP_40 (original name was: gnl|Prokka|IMNAJMDP_40)
  gnlProkkaIMNAJMDP_41 (original name was: gnl|Prokka|IMNAJMDP_41)

Compact view
gnlProkkaIMNAJMDP_1 - Region 1 - NI-siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 18,312 nt. (total: 18,312 nt) Show pHMM detection rules used
Region on contig edge.
NI-siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaIMNAJMDP_6 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 5,498 nt. (total: 5,498 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaIMNAJMDP_8 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 139,154 - 168,226 nt. (total: 29,073 nt) Show pHMM detection rules used
Region on contig edge.
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

gnlProkkaIMNAJMDP_13 - Region 1 - HR-T2PKS,hglE-KS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 60,429 - 106,993 nt. (total: 46,565 nt) Show pHMM detection rules used
Region on contig edge.
HR-T2PKS: (hr-t2pks-ksa and (t2fas or APE_KS2 or ketoacyl-synt))
hglE-KS: (hglE or hglD)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 60428 - 106993:
Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:
  (mal)
Non-colinear ordering:
  ctg13_88 + ctg13_87

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg13_88: mal
  PKS_AT (574..872): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 75.0%
    inactive: 66.7%
    2-Rhyd-Malonyl-CoA: 54.2%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 99.3
    Methoxymalonyl-CoA: 51.6
    Methylmalonyl-CoA: 33.3
    inactive: 30.2
    Propionyl-CoA: 18.5
    CHC-CoA: 12.5
    trans-1,2-CPDA: 0.0
    fatty_acid: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0

gnlProkkaIMNAJMDP_16 - Region 1 - ectoine,lanthipeptide-class-iii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 53,827 - 77,590 nt. (total: 23,764 nt) Show pHMM detection rules used
Region on contig edge.
ectoine: ectoine_synt
lanthipeptide-class-iii: (micKC and not PKS_KS)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg16_61

ctg16_62
Leader:
MNQVLELQKLSYNEESGQPAVD
Core:
K T P T T F T T T T T I T T L S T V S N N C
Core with dehydrations:
K Dhb P Dhb Dhb F Dhb Dhb Dhb Dhb Dhb I Dhb Dhb L Dha Dhb V Dha N N Cys

#### MIBiG 3.1 matches for ctg16_62

31.8% BGC0000582 (ADR72962.1): Linaridin: cypemycin
1
K T P T T F T T T T T I T T L S T V S N N C
22
T P T T + S T+ C
1
A T P A T P T V A Q F V I Q G S T I C L V C
22
26.1% BGC0002111 (EVG22_32245)and 1 other:
BGC0002111 (multiple genes) Lanthipeptide: andalusicin A or andalusicin B
Lanthipeptide: andalusicin A or andalusicin B
16
S T V S N N C
22
S T+S N N C
17
S T I S N N C
23

#### antiSMASH-DB 4.0 matches for ctg16_62

100.0% NZ_CP019985.1: Lanthipeptides: BC8716_RS22585_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S N N C
22
K T P T T F T T T T T I T T L S T V S N N C
1
K T P T T F T T T T T I T T L S T V S N N C
22
95.5% NZ_CP019985.1: Lanthipeptides: BC8716_RS22580_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S N N C
22
K T P T T F T T T T T I T T L S T V S N C
1
K T P T T F T T T T T I T T L S T V S Q N C
22
54.5% NZ_JAFFJY010000011.1: Lanthipeptides: JVX89_RS12320_lanthipeptide
2
T P T T F T T T T T I T T L S T V S N N C
22
T P T T T T L S T+S N C
4
T P T T V T T V G----L S T I S N G C
20
with 16 more sequence matches
50.0% NZ_CP003923.1 and 4 others:
NZ_CP042163.1 Lanthipeptides: FPV17_RS21690_lanthipeptide NZ_CP117834.1 Lanthipeptides: PQ477_RS10645_lanthipeptide NZ_KV917380.1 Lanthipeptides: BK583_RS20900_lanthipeptide NZ_SNUX01000002.1 Lanthipeptides: E2L03_RS20345_lanthipeptide
Lanthipeptides: BLEG1_RS21175_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S N N C
22
K+P T T T T T T S T S N C
5
K S P A T I T T T T T A V G W S T A S N G C
26
50.0% NZ_FOHE01000012.1 and 1 other:
NZ_FOHE01000012.1 Lanthipeptides: BMX40_RS20540_lanthipeptide
Lanthipeptides: BMX40_RS20545_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
+T T T I L S T V S N+C
3
W T W T V T I F-L S T V S N H C
18
46.2% NZ_CP003923.1 and 4 others:
NZ_CP042163.1 Lanthipeptides: FPV17_RS21685_lanthipeptide NZ_CP117834.1 Lanthipeptides: PQ477_RS10640_lanthipeptide NZ_KV917380.1 Lanthipeptides: BK583_RS20905_lanthipeptide NZ_SNUX01000002.1 Lanthipeptides: E2L03_RS20340_lanthipeptide
Lanthipeptides: BLEG1_RS21170_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S N N C
22
K+P T T T T T+ S T S N+C
5
K S P A T I T T T R T V I G W S T A S N S C
26
45.5% NC_014551.1 and 5 others:
NC_017188.1 Lanthipeptides: BAMTA208_RS20930_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20755_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03870_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20395_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19840_lanthipeptide
Lanthipeptides: BAMF_RS41655_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
T T T I S T+S N N C
2
L T L I T T I V G S S T I S N N C
18
45.5% NZ_CP026010.1 and 18 others:
NZ_CP026010.1 Lanthipeptides: BS11774_RS22075_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21845_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21825_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04870_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04850_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19000_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19020_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21930_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21925_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21920_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21910_lanthipeptide NZ_JALAPV010000012.1 Lanthipeptides: MOC91_RS19790_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18885_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18865_lanthipeptide NZ_JALAVZ010000001.1 Lanthipeptides: MOF00_RS00410_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19510_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19505_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19490_lanthipeptide
Lanthipeptides: BS11774_RS22085_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
T T T I S T+S N N C
2
L T L I T T I V G T S T I S N N C
18
41.4% NZ_FOHE01000012.1: Lanthipeptides: BMX40_RS20340_lanthipeptide
3
P T T F T T T T T I T T L-S T V S N N C
22
P T T + +T T S T V S N N C
5
P T I T T V S A I L T T F W S T V S N N C
25
40.9% NC_014551.1 and 27 others:
NC_014551.1 Lanthipeptides: BAMF_RS41665_lanthipeptide NC_014551.1 Lanthipeptides: BAMF_RS41670_lanthipeptide NC_017188.1 Lanthipeptides: BAMTA208_RS20950_lanthipeptide NC_017188.1 Lanthipeptides: BAMTA208_RS20940_lanthipeptide NC_017188.1 Lanthipeptides: BAMTA208_RS20945_lanthipeptide NZ_CP026010.1 Lanthipeptides: BS11774_RS22090_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20775_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20765_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20770_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21840_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21835_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04865_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04860_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03890_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03880_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03885_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19010_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19005_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20385_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20380_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18880_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18875_lanthipeptide NZ_JALAUK010000033.1 Lanthipeptides: MOE38_RS18580_lanthipeptide NZ_JALAVZ010000001.1 Lanthipeptides: MOF00_RS00405_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19500_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19860_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19855_lanthipeptide
Lanthipeptides: BAMF_RS41675_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
T T T+ S T+S N N C
2
L T L I T T V V G T S T I S N N C
18
40.9% NZ_LN868937.1: Lanthipeptides: BN2144_RS19915_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
F T+ T + T S T+S N+C
6
F T S V T L L V T T S T I S N H C
22
40.0% NZ_CP003923.1 and 13 others:
NZ_CP003923.1 Lanthipeptides: BLEG1_RS21185_lanthipeptide NZ_CP042163.1 Lanthipeptides: FPV17_RS21700_lanthipeptide NZ_CP042163.1 Lanthipeptides: FPV17_RS21695_lanthipeptide NZ_CP042163.1 Lanthipeptides: FPV17_RS21680_lanthipeptide NZ_CP117834.1 Lanthipeptides: PQ477_RS10655_lanthipeptide NZ_CP117834.1 Lanthipeptides: PQ477_RS10650_lanthipeptide NZ_CP117834.1 Lanthipeptides: PQ477_RS10635_lanthipeptide NZ_KV917380.1 Lanthipeptides: BK583_RS20910_lanthipeptide NZ_KV917380.1 Lanthipeptides: BK583_RS20895_lanthipeptide NZ_KV917380.1 Lanthipeptides: BK583_RS20890_lanthipeptide NZ_SNUX01000002.1 Lanthipeptides: E2L03_RS20350_lanthipeptide NZ_SNUX01000002.1 Lanthipeptides: E2L03_RS20335_lanthipeptide NZ_SNUX01000002.1 Lanthipeptides: E2L03_RS20355_lanthipeptide
Lanthipeptides: BLEG1_RS21165_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S N N C
22
K+P T T T T T S T S N+C
9
K S P A T V T I T T T A V G W S T A S N D C
30
39.1% NZ_LN868937.1 and 1 other:
NZ_LN868937.1 Lanthipeptides: BN2144_RS20100_lanthipeptide
Lanthipeptides: BN2144_RS20095_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
+T T T+ S T+S N N C
5
Y T I F T T L I G T S T I S N N C
21
36.4% NC_014551.1 and 13 others:
NC_017188.1 Lanthipeptides: BAMTA208_RS20935_lanthipeptide NZ_CP026010.1 Lanthipeptides: BS11774_RS22080_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20760_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21830_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04855_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03875_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19015_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20390_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21915_lanthipeptide NZ_JALAPV010000012.1 Lanthipeptides: MOC91_RS19785_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18870_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19495_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19845_lanthipeptide
Lanthipeptides: BAMF_RS41660_lanthipeptide
6
F T T T T T I T T L S T V S N N C
22
+T T T+ S T+S N+C
4
W T L L T T L I G T S T I S N S C
20
31.8% NZ_BMVC01000018.1 and 5 others:
NZ_BMVC01000018.1 Lanthipeptides: IE282_RS34445_lanthipeptide NZ_BMVC01000018.1 Lanthipeptides: IE282_RS34455_lanthipeptide NZ_JALMDK010000006.1 Lanthipeptides: MZC64_RS26320_lanthipeptide NZ_JANBBG010000004.1 Lanthipeptides: allorf_1567890_1567982_lanthipeptide NZ_JANBBG010000004.1 Lanthipeptides: allorf_1567737_1567829_lanthipeptide
Lanthipeptides: IE282_RS34450_lanthipeptide
16
S T V S N N C
22
S T V S N N C
3
S T V S N N C
9
31.8% NZ_CP066711.1: Lanthipeptides: JGZ56_RS07825_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S N N C
22
K +T + S T+S N+C
1
K G G R G L S T L L S F L G G S T I S N H C
22
30.0% NZ_CP066711.1: Lanthipeptides: allorf_1652598_1652744_lanthipeptide
5
T F T T T T T I T T L S T V S N N C
22
T T T+ L S T+S N C
8
T V E I T M T V Y G L S T I S N K C
25
27.3% NZ_CP014222.1: Lanthipeptides: VN23_RS10390_lanthipeptide
11
T I T T L S T V S N N C
22
+ S T V S N+C
2
Q V A D W S T V S N H C
13
26.1% NZ_CP035727.2 and 6 others:
NZ_CP035727.2 Lanthipeptides: EVG22_RS16235_lanthipeptide NZ_CP035727.2 Lanthipeptides: EVG22_RS16230_lanthipeptide NZ_CP035727.2 Lanthipeptides: EVG22_RS16225_lanthipeptide NZ_CP035727.2 Lanthipeptides: EVG22_RS16220_lanthipeptide NZ_CP035727.2 Lanthipeptides: EVG22_RS16215_lanthipeptide NZ_CP035727.2 Lanthipeptides: EVG22_RS16210_lanthipeptide
Lanthipeptides: EVG22_RS16240_lanthipeptide
16
S T V S N N C
22
S T+S N N C
17
S T I S N N C
23
ctg16_63
Leader:
MNQVLELQKLSYNEESGQPAVD
Core:
K T P T T F T T T T T I T T L S T V S Q N C
Core with dehydrations:
K Dhb P Dhb Dhb F Dhb Dhb Dhb Dhb Dhb I Dhb Dhb L Dha Dhb V Dha Q N Cys

#### MIBiG 3.1 matches for ctg16_63

31.8% BGC0000582 (ADR72962.1): Linaridin: cypemycin
1
K T P T T F T T T T T I T T L S T V S Q N C
22
T P T T + S T+ C
1
A T P A T P T V A Q F V I Q G S T I C L V C
22
30.4% BGC0002111 (EVG22_32245): Lanthipeptide: andalusicin A or andalusicin B
10
T T I T T L S T V S Q N C
22
T T S T+S N C
11
T T G A W A S T I S N N C
23
30.4% BGC0002111 (multiple genes): Lanthipeptide: andalusicin A or andalusicin B
10
T T I T T L S T V S Q N C
22
T T S T+S N C
11
T T G V W A S T I S N N C
23

#### antiSMASH-DB 4.0 matches for ctg16_63

100.0% NZ_CP019985.1: Lanthipeptides: BC8716_RS22580_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S Q N C
22
K T P T T F T T T T T I T T L S T V S Q N C
1
K T P T T F T T T T T I T T L S T V S Q N C
22
95.5% NZ_CP019985.1: Lanthipeptides: BC8716_RS22585_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S Q N C
22
K T P T T F T T T T T I T T L S T V S N C
1
K T P T T F T T T T T I T T L S T V S N N C
22
42.3% NZ_CP003923.1 and 4 others:
NZ_CP042163.1 Lanthipeptides: FPV17_RS21685_lanthipeptide NZ_CP117834.1 Lanthipeptides: PQ477_RS10640_lanthipeptide NZ_KV917380.1 Lanthipeptides: BK583_RS20905_lanthipeptide NZ_SNUX01000002.1 Lanthipeptides: E2L03_RS20340_lanthipeptide
Lanthipeptides: BLEG1_RS21170_lanthipeptide
1
K T P T T F T T T T T I T T L S T V S Q N C
22
K+P T T T T T+ S T S +C
5
K S P A T I T T T R T V I G W S T A S N S C
26
with 7 more sequence matches
40.9% NC_014551.1 and 5 others:
NC_017188.1 Lanthipeptides: BAMTA208_RS20930_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20755_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03870_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20395_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19840_lanthipeptide
Lanthipeptides: BAMF_RS41655_lanthipeptide
6
F T T T T T I T T L S T V S Q N C
22
T T T I S T+S N C
2
L T L I T T I V G S S T I S N N C
18
40.9% NZ_CP026010.1 and 18 others:
NZ_CP026010.1 Lanthipeptides: BS11774_RS22075_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21845_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21825_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04870_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04850_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19000_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19020_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21930_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21925_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21920_lanthipeptide NZ_JAHVOC010000011.1 Lanthipeptides: KXD37_RS21910_lanthipeptide NZ_JALAPV010000012.1 Lanthipeptides: MOC91_RS19790_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18885_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18865_lanthipeptide NZ_JALAVZ010000001.1 Lanthipeptides: MOF00_RS00410_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19510_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19505_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19490_lanthipeptide
Lanthipeptides: BS11774_RS22085_lanthipeptide
6
F T T T T T I T T L S T V S Q N C
22
T T T I S T+S N C
2
L T L I T T I V G T S T I S N N C
18
37.9% NZ_FOHE01000012.1: Lanthipeptides: BMX40_RS20340_lanthipeptide
3
P T T F T T T T T I T T L-S T V S Q N C
22
P T T + +T T S T V S N C
5
P T I T T V S A I L T T F W S T V S N N C
25
36.4% NC_014551.1 and 27 others:
NC_014551.1 Lanthipeptides: BAMF_RS41665_lanthipeptide NC_014551.1 Lanthipeptides: BAMF_RS41670_lanthipeptide NC_017188.1 Lanthipeptides: BAMTA208_RS20950_lanthipeptide NC_017188.1 Lanthipeptides: BAMTA208_RS20940_lanthipeptide NC_017188.1 Lanthipeptides: BAMTA208_RS20945_lanthipeptide NZ_CP026010.1 Lanthipeptides: BS11774_RS22090_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20775_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20765_lanthipeptide NZ_CP032146.1 Lanthipeptides: D2M30_RS20770_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21840_lanthipeptide NZ_CP054584.1 Lanthipeptides: HT135_RS21835_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04865_lanthipeptide NZ_CP061284.1 Lanthipeptides: ICJ61_RS04860_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03890_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03880_lanthipeptide NZ_CP062984.1 Lanthipeptides: IL989_RS03885_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19010_lanthipeptide NZ_CP065858.1 Lanthipeptides: I7X10_RS19005_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20385_lanthipeptide NZ_DF836084.1 Lanthipeptides: CMW1_RS20380_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18880_lanthipeptide NZ_JALAQA010000009.1 Lanthipeptides: MOD07_RS18875_lanthipeptide NZ_JALAUK010000033.1 Lanthipeptides: MOE38_RS18580_lanthipeptide NZ_JALAVZ010000001.1 Lanthipeptides: MOF00_RS00405_lanthipeptide NZ_JANDGG010000010.1 Lanthipeptides: NKU38_RS19500_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19860_lanthipeptide NZ_KQ236689.1 Lanthipeptides: AD710_RS19855_lanthipeptide
Lanthipeptides: BAMF_RS41675_lanthipeptide
6
F T T T T T I T T L S T V S Q N C
22
T T T+ S T+S N C
2
L T L I T T V V G T S T I S N N C
18
36.4% NZ_LN868937.1: Lanthipeptides: BN2144_RS19915_lanthipeptide
6
F T T T T T I T T L S T V S Q N C
22
F T+ T + T S T+S +C
6
F T S V T L L V T T S T I S N H C
22
34.8% NZ_LN868937.1 and 1 other:
NZ_LN868937.1 Lanthipeptides: BN2144_RS20100_lanthipeptide
Lanthipeptides: BN2144_RS20095_lanthipeptide
6
F T T T T T I T T L S T V S Q N C
22
+T T T+ S T+S N C
5
Y T I F T T L I G T S T I S N N C
21
31.8% NZ_GL545262.1: Lanthipeptides: HMPREF0798_RS11830_lanthipeptide
7
T T T T T I T T L S T V S Q N C
22
+ +T + L S T+S Q+C
1
S I S T L V A F L S T I S Q H C
16

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg16_62 - Class III
  Cleavage pHMM score: 2.60
  RODEO score: 0
  Monoisotopic mass: 2098.1 Da
  Molecular weight: 2099.3 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2117.3 Da N = 1
    2135.3 Da N = 2
    2153.4 Da N = 3
    2171.4 Da N = 4
    2189.4 Da N = 5
    2207.4 Da N = 6
    2225.4 Da N = 7
    2243.5 Da N = 8
    2261.5 Da N = 9
    2279.5 Da N = 10
    2297.5 Da N = 11
    2315.5 Da N = 12
ctg16_63 - Class III
  Cleavage pHMM score: 2.60
  RODEO score: 0
  Monoisotopic mass: 2112.2 Da
  Molecular weight: 2113.3 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2131.4 Da N = 1
    2149.4 Da N = 2
    2167.4 Da N = 3
    2185.4 Da N = 4
    2203.4 Da N = 5
    2221.5 Da N = 6
    2239.5 Da N = 7
    2257.5 Da N = 8
    2275.5 Da N = 9
    2293.5 Da N = 10
    2311.6 Da N = 11
    2329.6 Da N = 12

gnlProkkaIMNAJMDP_28 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1 - 19,749 nt. (total: 19,749 nt) Show pHMM detection rules used
Region on contig edge.
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
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Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

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Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
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No matches found.